Rami Hershkoviz

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Sela Uri; Sharabi Amir; Dayan Molly; Hershkoviz Rami; Mozes Edna
The role of dendritic cells in the mechanism of action of a peptide that ameliorates lupus in murine models.
Sela Uri; Dayan Molly; Hershkoviz Rami; Lider Ofer; Mozes Edna
A peptide that ameliorates lupus up-regulates the diminished expression of early growth response factors 2 and 3.
Sela Uri; Brill Alexander; Kalchenko Vyacheslav; Dashevsky Olga; Hershkoviz Rami
Allicin inhibits blood vessel growth and downregulates Akt phosphorylation and actin polymerization.

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All Publications

2009: Sela Uri; Sharabi Amir; Dayan Molly; Hershkoviz Rami; Mozes Edna
The role of dendritic cells in the mechanism of action of a peptide that ameliorates lupus in murine models.
Immunology 2009;128(1 Suppl):e395-405.
2008: Sela Uri; Dayan Molly; Hershkoviz Rami; Lider Ofer; Mozes Edna
A peptide that ameliorates lupus up-regulates the diminished expression of early growth response factors 2 and 3.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1584-91.
2008: Sela Uri; Brill Alexander; Kalchenko Vyacheslav; Dashevsky Olga; Hershkoviz Rami
Allicin inhibits blood vessel growth and downregulates Akt phosphorylation and actin polymerization.
Nutrition and cancer 2008;60(3):412-20.
2006: Sela Uri; Dayan Molly; Hershkoviz Rami; Cahalon Liora; Lider Ofer; Mozes Edna
The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses.
European journal of immunology 2006;36(11):2971-80.
2005: Sela Uri; Mauermann Nora; Hershkoviz Rami; Zinger Heidy; Dayan Molly; Cahalon Liora; Liu Jian Ping; Mozes Edna; Lider Ofer
The inhibition of autoreactive T cell functions by a peptide based on the CDR1 of an anti-DNA autoantibody is via TGF-beta-mediated suppression of LFA-1 and CD44 expression and function.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7255-63.
2005: Bruck Rafael; Aeed Hussein; Brazovsky Eli; Noor Talia; Hershkoviz Rami
Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(3):613-21.
2005: Zanin-Zhorov Alexandra; Bruck Rafael; Tal Guy; Oren Shirly; Aeed Hussein; Hershkoviz Rami; Cohen Irun R; Lider Ofer
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3227-36.
2005: Abdul-Hai A; Hershkoviz R; Weiss L; Lider O; Slavin S
Effect of Linomide on adhesion molecules, TNF-alpha, nitrogen oxide, and cell adhesion.
International immunopharmacology 2005;5(2):231-9.
2005: Sela Uri; Hershkoviz Rami; Cahalon Liora; Lider Ofer; Mozes Edna
Down-regulation of stromal cell-derived factor-1alpha-induced T cell chemotaxis by a peptide based on the complementarity-determining region 1 of an anti-DNA autoantibody via up-regulation of TGF-beta secretion.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):302-9.
2004: Brill A; Baram D; Sela U; Salamon P; Mekori Y A; Hershkoviz R
Induction of mast cell interactions with blood vessel wall components by direct contact with intact T cells or T cell membranes in vitro.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(11):1725-31.
2004: Lang Alon; Lahav Maor; Sakhnini Emad; Barshack Iris; Fidder Herma H; Avidan Benjamin; Bardan Eitan; Hershkoviz Rami; Bar-Meir Simon; Chowers Yehuda
Allicin inhibits spontaneous and TNF-alpha induced secretion of proinflammatory cytokines and chemokines from intestinal epithelial cells.
Clinical nutrition (Edinburgh, Scotland) 2004;23(5):1199-208.
2004: Hecht Iris; Hershkoviz Rami; Shivtiel Shoham; Lapidot Tzvi; Cohen Irun R; Lider Ofer; Cahalon Liora
Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling.
Journal of leukocyte biology 2004;75(6):1139-46.
2004: Sotnikov Ilya; Hershkoviz Rami; Grabovsky Valentin; Ilan Neta; Cahalon Liora; Vlodavsky Israel; Alon Ronen; Lider Ofer
Enzymatically quiescent heparanase augments T cell interactions with VCAM-1 and extracellular matrix components under versatile dynamic contexts.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5185-93.
2004: Avigdor Abraham; Goichberg Polina; Shivtiel Shoham; Dar Ayelet; Peled Amnon; Samira Sarit; Kollet Orit; Hershkoviz Rami; Alon Ronen; Hardan Izhar; Ben-Hur Herzl; Naor David; Nagler Arnon; Lapidot Tsvee
CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow.
Blood 2004;103(8):2981-9.
2004: Sela Uri; Ganor Sharon; Hecht Iris; Brill Alexander; Miron Talia; Rabinkov Aharon; Wilchek Meir; Mirelman David; Lider Ofer; Hershkoviz Rami
Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression.
Immunology 2004;111(4):391-9.
2003: Zanin-Zhorov Alexandra; Hershkoviz Rami; Hecht Iris; Cahalon Liora; Lider Ofer
Fibronectin-associated Fas ligand rapidly induces opposing and time-dependent effects on the activation and apoptosis of T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5882-9.
2003: Bruck Rafael; Wardi Joram; Aeed Hussein; Avni Yona; Shirin Haim; Avinoach Ilana; Shahmurov Mark; Hershkoviz Rami
Glycine modulates cytokine secretion, inhibits hepatic damage and improves survival in a model of endotoxemia in mice.
Liver international : official journal of the International Association for the Study of the Liver 2003;23(4):276-82.
2003: Milo Olga; Cotter Gad; Kaluski Edo; Brill Alex; Blatt Alex; Krakover Ricardo; Vered Zvi; Hershkoviz Rami
Comparison of inflammatory and neurohormonal activation in cardiogenic pulmonary edema secondary to ischemic versus nonischemic causes.
The American journal of cardiology 2003;92(2):222-6.
2003: Hecht Iris; Cahalon Liora; Hershkoviz Rami; Lahat Adi; Franitza Suzanne; Lider Ofer
Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis.
International immunology 2003;15(1):29-38.
2002: Ariel Amiram; Novick Daniela; Rubinstein Menachem; Dinarello Charles A; Lider Ofer; Hershkoviz Rami
IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.
Journal of leukocyte biology 2002;72(1):192-8.
2002: Flaishon Liat; Topilski Ian; Shoseyov David; Hershkoviz Rami; Fireman Elizabeth; Levo Yoram; Marmor Sylvia; Shachar Idit
Cutting edge: anti-inflammatory properties of low levels of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3707-11.
2002: Matza Didi; Lantner Frida; Bogoch Yoel; Flaishon Liat; Hershkoviz Rami; Shachar Idit
Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3018-23.
2001: Flaishon L; Lantner F; Hershkoviz R; Levo Y; Shachar I
Low levels of IFN-gamma down-regulate the integrin-dependent adhesion of B cells by activating a pathway that interferes with cytoskeleton rearrangement.
The Journal of biological chemistry 2001;276(50):46701-6.
2001: Brill A; Franitza S; Lider O; Hershkoviz R
Regulation of T-cell interaction with fibronectin by transforming growth factor-beta is associated with altered Pyk2 phosphorylation.
Immunology 2001;104(2):149-56.
2001: Dotan I; Hallak A; Arber N; Santo M; Alexandrowitz A; Knaani Y; Hershkoviz R; Brazowski E; Halpern Z
Low-dose low-molecular weight heparin (enoxaparin) is effective as adjuvant treatment in active ulcerative colitis: an open trial.
Digestive diseases and sciences 2001;46(10):2239-44.
2001: Baram D; Vaday G G; Salamon P; Drucker I; Hershkoviz R; Mekori Y A
Human mast cells release metalloproteinase-9 on contact with activated T cells: juxtacrine regulation by TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):4008-16.
2001: Dotan I; Hershkoviz R; Karmeli F; Brazowski E; Peled Y; Rachmilewitz D; Halpern Z
Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats.
Alimentary pharmacology & therapeutics 2001;15(10):1687-97.
2001: Kenet G; Wardi J; Avni Y; Aeed H; Shirin H; Zaidel L; Hershkoviz R; Bruck R
Amelioration of experimental colitis by thalidomide.
The Israel Medical Association journal : IMAJ 2001;3(9):644-8.
2001: Vaday G G; Franitza S; Schor H; Hecht I; Brill A; Cahalon L; Hershkoviz R; Lider O
Combinatorial signals by inflammatory cytokines and chemokines mediate leukocyte interactions with extracellular matrix.
Journal of leukocyte biology 2001;69(6):885-92.
2001: Brill A; Hershkoviz R; Vaday G G; Chowers Y; Lider O
Augmentation of RANTES-induced extracellular signal-regulated kinase mediated signaling and T cell adhesion by elastase-treated fibronectin.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7121-7.
2001: Kollet O; Spiegel A; Peled A; Petit I; Byk T; Hershkoviz R; Guetta E; Barkai G; Nagler A; Lapidot T
Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice.
Blood 2001;97(10):3283-91.
2001: Ariel A; Hershkoviz R; Altbaum-Weiss I; Ganor S; Lider O
Cell surface-expressed moesin-like receptor regulates T cell interactions with tissue components and binds an adhesion-modulating IL-2 peptide generated by elastase.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3052-60.
2000: Vaday G G; Baram D; Salamon P; Drucker I; Hershkoviz R; Mekori Y A
Cytokine production and matrix metalloproteinase (MMP)-9 release by human mast cells following cell-to-cell contact with activated T cells.
The Israel Medical Association journal : IMAJ 2000;2 Suppl():26.
2000: Vaday G G; Hershkoviz R; Rahat M A; Lahat N; Cahalon L; Lider O
Fibronectin-bound TNF-alpha stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis.
Journal of leukocyte biology 2000;68(5):737-47.
2000: Flaishon L; Hershkoviz R; Lantner F; Lider O; Alon R; Levo Y; Flavell R A; Shachar I
Autocrine secretion of interferon gamma negatively regulates homing of immature B cells.
The Journal of experimental medicine 2000;192(9):1381-8.
2000: Franitza S; Hershkoviz R; Kam N; Lichtenstein N; Vaday G G; Alon R; Lider O
TNF-alpha associated with extracellular matrix fibronectin provides a stop signal for chemotactically migrating T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2738-47.
2000: Ariel A; Lider O; Brill A; Cahalon L; Savion N; Varon D; Hershkoviz R
Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators.
Immunology 2000;100(3):345-51.
2000: Bruck R; Hershkoviz R; Lider O; Shirin H; Aeed H; Halpern Z
Non-peptidic analogs of the cell adhesion motif RGD prevent experimental liver injury.
The Israel Medical Association journal : IMAJ 2000;2 Suppl():74-80.
2000: Zeltzer E; Bernheim J; Korzets Z; Zeeli D; Rathaus M; Mekori Y A; Hershkoviz R
Diminished chemokine and cytokine-induced adhesion of CD4+ T cells to extracellular matrix ligands in patients with end-stage renal failure.
The Israel Medical Association journal : IMAJ 2000;2(4):282-6.
2000: Levite M; Cahalon L; Peretz A; Hershkoviz R; Sobko A; Ariel A; Desai R; Attali B; Lider O
Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins.
The Journal of experimental medicine 2000;191(7):1167-76.
2000: Hershkoviz R; Schor H; Ariel A; Hecht I; Cohen I R; Lider O; Cahalon L
Disaccharides generated from heparan sulphate or heparin modulate chemokine-induced T-cell adhesion to extracellular matrix.
Immunology 2000;99(1):87-93.
1999: Hershkoviz R; Bruck R; Aeed H; Shirin H; Halpern Z
Treatment of concanavalin A-induced hepatitis in mice with low molecular weight heparin.
Journal of hepatology 1999;31(5):834-40.
1999: Rabinovich G A; Ariel A; Hershkoviz R; Hirabayashi J; Kasai K I; Lider O
Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1.
Immunology 1999;97(1):100-6.
1998: Ariel A; Yavin E J; Hershkoviz R; Avron A; Franitza S; Hardan I; Cahalon L; Fridkin M; Lider O
IL-2 induces T cell adherence to extracellular matrix: inhibition of adherence and migration by IL-2 peptides generated by leukocyte elastase.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2465-72.
1998: Shirin H; Bruck R; Aeed H; Frenkel D; Kenet G; Zaidel L; Avni Y; Halpern Z; Hershkoviz R
Pentoxifylline prevents concanavalin A-induced hepatitis by reducing tumor necrosis factor alpha levels and inhibiting adhesion of T lymphocytes to extracellular matrix.
Journal of hepatology 1998;29(1):60-7.
1998: Levite M; Cahalon L; Hershkoviz R; Steinman L; Lider O
Neuropeptides, via specific receptors, regulate T cell adhesion to fibronectin.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):993-1000.
1997: Shirin H; Bruck R; Aeed H; Hershkoviz R; Lider O; Kenet G; Avni Y; Halpern Z
Effects of intravenous immunoglobulins on T-cell mediated, concanavalin A-induced hepatitis in mice.
Liver 1997;17(6):275-80.
1997: Zeltzer E; Bernheim J; Korzets Z; Rathaus M; Mekori Y A; Hershkoviz R
Diminished adhesion of CD4+ T cells from dialysis patients to extracellular matrix and its components fibronectin and laminin.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1997;12(12):2618-22.
1997: Baram D; Rashkovsky M; Hershkoviz R; Drucker I; Reshef T; Ben-Shitrit S; Mekori Y A
Inhibitory effects of low molecular weight heparin on mediator release by mast cells: preferential inhibition of cytokine production and mast cell-dependent cutaneous inflammation.
Clinical and experimental immunology 1997;110(3):485-91.
1997: Ariel A; Hershkoviz R; Cahalon L; Williams D E; Akiyama S K; Yamada K M; Chen C; Alon R; Lapidot T; Lider O
Induction of T cell adhesion to extracellular matrix or endothelial cell ligands by soluble or matrix-bound interleukin-7.
European journal of immunology 1997;27(10):2562-70.
1997: Cahalon L; Lider O; Schor H; Avron A; Gilat D; Hershkoviz R; Margalit R; Eshel A; Shoseyev O; Cohen I R
Heparin disaccharides inhibit tumor necrosis factor-alpha production by macrophages and arrest immune inflammation in rodents.
International immunology 1997;9(10):1517-22.
1997: Miron S; Kachalsky S G; Hershkoviz R; Lider O
Pervanadate-induced adhesion of CD4+ T cell to fibronectin is associated with tyrosine phosphorylation of paxillin.
Journal of leukocyte biology 1997;62(3):405-13.
1997: Bruck R; Hershkoviz R; Lider O; Shirin H; Aeed H; Halpern Z
The use of synthetic analogues of Arg-Gly-Asp (RGD) and soluble receptor of tumor necrosis factor to prevent acute and chronic experimental liver injury.
The Yale journal of biology and medicine 1997;70(4):391-402.
1997: Hershkoviz R; Preciado-Patt L; Lider O; Fridkin M; Dastych J; Metcalfe D D; Mekori Y A
Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion.
The American journal of physiology 1997;273(1 Pt 1):C179-87.
1997: Hershkoviz R; Preciado-Patt L; Lider O; Fridkin M; Mekori Y A
Mast cell adhesion to extracellular matrix: local effects of acute phase reactants.
International archives of allergy and immunology 1997;113(1-3):295-6.
1997: Bruck R; Shirin H; Hershkoviz R; Lider O; Kenet G; Aeed H; Matas Z; Zaidel L; Halpern Z
Analysis of Arg-Gly-Asp mimetics and soluble receptor of tumour necrosis factor as therapeutic modalities for concanavalin A induced hepatitis in mice.
Gut 1997;40(1):133-8.
1996: Frankel G; Lider O; Hershkoviz R; Mould A P; Kachalsky S G; Candy D C; Cahalon L; Humphries M J; Dougan G
The cell-binding domain of intimin from enteropathogenic Escherichia coli binds to beta1 integrins.
The Journal of biological chemistry 1996;271(34):20359-64.
1996: Bruck R; Hershkoviz R; Lider O; Aeed H; Zaidel L; Matas Z; Barg J; Halpern Z
Inhibition of experimentally-induced liver cirrhosis in rats by a nonpeptidic mimetic of the extracellular matrix-associated Arg-Gly-Asp epitope.
Journal of hepatology 1996;24(6):731-8.
1996: Hershkoviz R; Marikovsky M; Gilat D; Lider O
Keratinocytes-associated chemokines and enzymatically quiescent heparanase induce the binding of resting CD4+ T cells.
The Journal of investigative dermatology 1996;106(2):243-8.
1996: Preciado-Patt L; Hershkoviz R; Fridkin M; Lider O
Serum amyloid A binds specific extracellular matrix glycoproteins and induces the adhesion of resting CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1189-95.
1996: Gilat D; Cahalon L; Hershkoviz R; Lider O
Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix.
Immunology today 1996;17(1):16-20.
1995: Hershkoviz R; Korzets Z; Rathaus M; Gilat D; Drucker I; Mekori Y A; Bernheim J
Inhibition by uraemic sera of CD4+ T-cell adhesion to extracellular matrix components.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1995;10(11):2065-9.
1995: Hershkoviz R; Mor F; Miao H Q; Vlodavsky I; Lider O
Differential effects of polysulfated polysaccharide on experimental encephalomyelitis, proliferation of autoimmune T cells, and inhibition of heparanase activity.
Journal of autoimmunity 1995;8(5):741-50.
1995: Lider O; Cahalon L; Gilat D; Hershkoviz R; Siegel D; Margalit R; Shoseyov O; Cohen I R
A disaccharide that inhibits tumor necrosis factor alpha is formed from the extracellular matrix by the enzyme heparanase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5037-41.
1995: Gilat D; Hershkoviz R; Goldkorn I; Cahalon L; Korner G; Vlodavsky I; Lider O
Molecular behavior adapts to context: heparanase functions as an extracellular matrix-degrading enzyme or as a T cell adhesion molecule, depending on the local pH.
The Journal of experimental medicine 1995;181(5):1929-34.
1995: Hershkoviz R; Goldkorn I; Lider O
Tumour necrosis factor-alpha interacts with laminin and functions as a pro-adhesive cytokine.
Immunology 1995;85(1):125-30.
1995: Hershkoviz R; Lider O; Bruck R; Aeed H; Greenspoon N; Halpern Z
Treatment of immune cell-mediated liver damage by nonpeptidic mimetics of the extracellular matrix-associated Arg-Gly-Asp epitope.
Journal of hepatology 1995;22(2):158-64.
1995: Lider O; Hershkoviz R; Kachalsky S G
Interactions of migrating T lymphocytes, inflammatory mediators, and the extracellular matrix.
Critical reviews in immunology 1995;15(3-4):271-83.
1994: Gilat D; Hershkoviz R; Mekori Y A; Vlodavsky I; Lider O
Regulation of adhesion of CD4+ T lymphocytes to intact or heparinase-treated subendothelial extracellular matrix by diffusible or anchored RANTES and MIP-1 beta.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(11):4899-906.
1994: Hershkoviz R; Lider O; Baram D; Reshef T; Miron S; Mekori Y A
Inhibition of T cell adhesion to extracellular matrix glycoproteins by histamine: a role for mast cell degranulation products.
Journal of leukocyte biology 1994;56(4):495-501.
1994: Preciado-Patt L; Levartowsky D; Prass M; Hershkoviz R; Lider O; Fridkin M
Inhibition of cell adhesion to glycoproteins of the extracellular matrix by peptides corresponding to serum amyloid A. Toward understanding the physiological role of an enigmatic protein.
European journal of biochemistry / FEBS 1994;223(1):35-42.
1994: Cahalon L; Hershkoviz R; Gilat D; Miller A; Akiyama S K; Yamada K M; Lider O
Functional interactions of fibronectin and TNF alpha: a paradigm of physiological linkage between cytokines and extracellular matrix moieties.
Cell adhesion and communication 1994;2(3):269-73.
1994: Hershkoviz R; Cahalon L; Miron S; Alon R; Sapir T; Akiyama S K; Yamada K M; Lider O
TNF-alpha associated with fibronectin enhances phorbol myristate acetate- or antigen-mediated integrin-dependent adhesion of CD4+ T cells via protein tyrosine phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(2):554-65.
1994: Greenspoon N; Hershkoviz R; Alon R; Gershonov E; Lavie B; Lider O
Novel psi-S-CH2 peptide-bond replacement and its utilization in the synthesis of nonpeptidic surrogates of the Leu-Asp-Val sequence that exhibit specific inhibitory activities on CD4+ T cell binding to fibronectin.
International journal of peptide and protein research 1994;43(5):417-24.
1994: Hershkoviz R; Melamed S; Greenspoon N; Lider O
Nonpeptidic analogues of the Arg-Gly-Asp (RGD) sequence specifically inhibit the adhesion of human tenon's capsule fibroblasts to fibronectin.
Investigative ophthalmology & visual science 1994;35(5):2585-91.
1994: Achiron A; Margalit R; Hershkoviz R; Markovits D; Reshef T; Melamed E; Cohen I R; Lider O
Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor alpha secretion.
The Journal of clinical investigation 1994;93(2):600-5.
1994: Hershkoviz R; Greenspoon N; Mekori Y A; Hadari R; Alon R; Kapustina G; Lider O
Inhibition of CD4+ T lymphocyte binding to fibronectin and immune-cell accumulation in inflammatory sites by non-peptidic mimetics of Arg-Gly-Asp.
Clinical and experimental immunology 1994;95(2):270-6.
1994: Alon R; Cahalon L; Hershkoviz R; Elbaz D; Reizis B; Wallach D; Akiyama S K; Yamada K M; Lider O
TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):1304-13.
1993: Varon D; Lider O; Dardik R; Shenkman B; Alon R; Hershkoviz R; Kapustina G; Savion N; Martinowitz U; Greenspoon N
Inhibition of integrin-mediated platelet aggregation, fibrinogen-binding, and interactions with extracellular matrix by nonpeptidic mimetics of Arg-Gly-Asp.
Thrombosis and haemostasis 1993;70(6):1030-6.
1993: Hardan I; Weiss L; Hershkoviz R; Greenspoon N; Alon R; Cahalon L; Reich S; Slavin S; Lider O
Inhibition of metastatic cell colonization in murine lungs and tumor-induced morbidity by non-peptidic Arg-Gly-Asp mimetics.
International journal of cancer. Journal international du cancer 1993;55(6):1023-8.
1993: Lider O; Hershkoviz R; Alon R; Greenspoon N
Structure-function analysis of integrin-mediated cell functions by novel nonpeptidic conformational mimetics of the Arg-Gly-Asp and Leu-Asp-Val amino acid sequences.
Annals of the New York Academy of Sciences 1993;696():402-3.
1993: Hershkoviz R; Alon R; Mekori Y A; Gilat D; Cahalon L; Miller A; Lider O
Heat-stressed CD4+ T lymphocytes: differential modulations of adhesiveness to extracellular matrix glycoproteins, proliferative responses and tumour necrosis factor-alpha secretion.
Immunology 1993;79(2):241-7.
1993: Alon R; Hershkoviz R; Bayer E A; Wilchek M; Lider O
Streptavidin blocks immune reactions mediated by fibronectin-VLA-5 recognition through an Arg-Gly-Asp mimicking site.
European journal of immunology 1993;23(4):893-8.
1993: Greenspoon N; Hershkoviz R; Alon R; Varon D; Shenkman B; Marx G; Federman S; Kapustina G; Lider O
Structural analysis of integrin recognition and the inhibition of integrin-mediated cell functions by novel nonpeptidic surrogates of the Arg-Gly-Asp sequence.
Biochemistry 1993;32(4):1001-8.
1993: Hershkoviz R; Gilat D; Miron S; Mekori Y A; Aderka D; Wallach D; Vlodavsky I; Cohen I R; Lider O
Extracellular matrix induces tumour necrosis factor-alpha secretion by an interaction between resting rat CD4+ T cells and macrophages.
Immunology 1993;78(1):50-7.
1993: Hershkoviz R; Cahalon L; Gilat D; Miron S; Miller A; Lider O
Physically damaged extracellular matrix induces TNF-alpha secretion by interacting resting CD4+ T cells and macrophages.
Scandinavian journal of immunology 1993;37(1):111-5.
1992: Miron S; Hershkoviz R; Tirosh I; Schechter Y; Yayun A; Lider O
Involvement of a protein kinase C and protein phosphatases in adhesion of CD4+ T cells to and detachment from extracellular matrix proteins.
Cellular immunology 1992;144(1):182-9.
1992: Hershkoviz R; Alon R; Gilat D; Lider O
Activated T lymphocytes and macrophages secrete fibronectin which strongly supports cell adhesion.
Cellular immunology 1992;141(2):352-61.
1992: Hershkoviz R; Mor F; Gilat D; Cohen I R; Lider O
T cells in the spinal cord in experimental autoimmune encephalomyelitis are matrix adherent and secrete tumor necrosis factor alpha.
Journal of neuroimmunology 1992;37(1-2):161-6.
1992: Hershkoviz R; Miron S; Cohen I R; Miller A; Lider O
T lymphocyte adhesion to the fibronectin and laminin components of the extracellular matrix is regulated by the CD4 molecule.
European journal of immunology 1992;22(1):7-13.
1991: Lider O; Miller A; Miron S; Hershkoviz R; Weiner H L; Zhang X M; Heber-Katz E
Nonencephalitogenic CD4-CD8- V alpha 2V beta 8.2+ anti-myelin basic protein rat T lymphocytes inhibit disease induction.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(4):1208-13.

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Rami Hershkoviz

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Physiology

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