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Peter Heutink

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Luba M Pardo; Patrizia Rizzu; Javier Simon Sanchez; Hazuki Takahashi; Wilma D J Van De Berg; Mark A van de Wiel; Morana Vitezic; piero carninci; Carsten O Daub; Margherita Francescatto; Abdullah Khamis; Gwenaël G R Leday; Yulia A Medvedeva; Peter Heutink
Regional differences in gene expression and promoter usage in aged human brains.
Sietske H Kevelam; Nienke L Postma; Chitra Prasad; Gajja S Salomons; Quinten Waisfisz; Nicole I Wolf; Truus E M Abbink; Ingrid M C Bakker; Ivo Baric; Susan Blaser; Marianna Bugiani; Annette Feigenbaum; Johannes Häberle; Peter Heutink; Warsha A Kanhai; Marjo S van der Knaap
Exome sequencing reveals mutated SLC19A3 in patients with an early-infantile, lethal encephalopathy.
Peter Holmans; Lesley Jones; Kari Majamaa; Maria Martinez; Florian Mittag; Huw R Morris; Valentina Moskvina; Michael A Nalls; Nayia Nicolaou; Mohamad Sadd; Claudia Schulte; Manu Sharma; Javier Simón-Sánchez; Andrew B Singleton; Hreinn Stefánsson; Alexey Vedernikov; Francesco Bettella; Jose M Bras; Alexis Brice; Finja Buchel; Alexandra Durr; Thomas Gasser; J Raphael Gibbs; Rita Guerreiro; John Hardy; Dena Hernandez; Peter Heutink; Nicholas W Wood; Nigel M Williams
A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.

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All Publications

2013: Luba M Pardo; Patrizia Rizzu; Javier Simon Sanchez; Hazuki Takahashi; Wilma D J Van De Berg; Mark A van de Wiel; Morana Vitezic; piero carninci; Carsten O Daub; Margherita Francescatto; Abdullah Khamis; Gwenaël G R Leday; Yulia A Medvedeva; Peter Heutink
Regional differences in gene expression and promoter usage in aged human brains.
Neurobiology of aging 2013;34(7):1825-36.
2013: Sietske H Kevelam; Nienke L Postma; Chitra Prasad; Gajja S Salomons; Quinten Waisfisz; Nicole I Wolf; Truus E M Abbink; Ingrid M C Bakker; Ivo Baric; Susan Blaser; Marianna Bugiani; Annette Feigenbaum; Johannes Häberle; Peter Heutink; Warsha A Kanhai; Marjo S van der Knaap
Exome sequencing reveals mutated SLC19A3 in patients with an early-infantile, lethal encephalopathy.
Brain : a journal of neurology 2013;136(Pt 5):1534-43.
2013: Peter Holmans; Lesley Jones; Kari Majamaa; Maria Martinez; Florian Mittag; Huw R Morris; Valentina Moskvina; Michael A Nalls; Nayia Nicolaou; Mohamad Sadd; Claudia Schulte; Manu Sharma; Javier Simón-Sánchez; Andrew B Singleton; Hreinn Stefánsson; Alexey Vedernikov; Francesco Bettella; Jose M Bras; Alexis Brice; Finja Buchel; Alexandra Durr; Thomas Gasser; J Raphael Gibbs; Rita Guerreiro; John Hardy; Dena Hernandez; Peter Heutink; Nicholas W Wood; Nigel M Williams
A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.
Human molecular genetics 2013;22(5):1039-49.
2013: Justus L Groen; Peter Heutink; Katja Ritz; Javier Simón-Sánchez; Majid Aramideh; Frank Baas; Zoltán Bochdanovits; Agnita J W Boon; Yue Fang; Bart P C van de Warrenburg; Jacobus J van Hilten; Marina A J Tijssen
Cervical dystonia and genetic common variation in the dopamine pathway.
Parkinsonism & related disorders 2013;19(3):346-9.
2012: Florian Mittag; Mike A Nalls; Mohamad Saad; Claudia Schulte; Manu Sharma; Javier Simón-Sánchez; Andrew B Singleton; Nicholas W Wood; Andreas Zell; Zoltan Bochdanovits; Alexis Brice; Finja Büchel; Thomas Gasser; J Raphael Gibbs; John Hardy; Dena G Hernandez; Peter Heutink; Andreas Jahn; Margaux Keller; Suzanne Lesage; Maria Martinez
Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities.
Human mutation 2012;33(12):1708-18.
2012: Margaux F Keller; Laura L Kilarski; Kari Majamaa; Maria Martinez; Florian Mittag; Huw R Morris; Valentina Moskvina; Michael A Nalls; Nayia Nicolaou; Mohamad Saad; Claudia Schulte; Manu Sharma; Javier Simón-Sánchez; Andrew B Singleton; Hreinn Stefánsson; Nigel Williams; Nicholas W Wood; Pauli Ylikotila; Francesco Bettella; Jose Bras; Alexis Brice; Finja Büchel; Alexandra Durr; Thomas Gasser; J Raphael Gibbs; Rita Guerreiro; John Hardy; Dena G Hernandez; Peter Heutink; Peter Holmans
Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease.
Human molecular genetics 2012;21(22):4996-5009.
2012: Peter Heutink; Matthijs Verhage
Neurodegeneration: new road leads back to the synapse.
Neuron 2012;75(6):935-8.
2012: Luba M Pardo; Giovanna Piras; Patrizia Rizzu; Andres Ruiz-Linares; Kristiaan J van der Gaag; Rosanna Asproni; Peter de Knijff; Attilio Gabbas; Maria Monne; Peter Heutink
Dissecting the genetic make-up of North-East Sardinia using a large set of haploid and autosomal markers.
European journal of human genetics : EJHG 2012;20(9):956-64.
2012: Javier Simón-Sánchez; Marion Smits; Leonard H Van den Berg; Natasja M van Schoor; Rob Willemsen; Petra E Cohn-Hokke; Christine E M De Die-Smulders; J Roos A de Graaf; Inge de Koning; Dorly J H Deeg; Elise G P Dopper; Peter Heutink; Renate K Hukema; Danielle Majoor-Krakauer; Nayia Nicolaou; Y A L Pijnenburg; Joost Raaphorst; Annemieke J M Rozemuller; H Jurgen Schelhaas; Harro Seelaar; John C van Swieten
The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
Brain : a journal of neurology 2012;135(Pt 3):723-35.
2012: Eva C Verbeek; Gonneke Willemsen; Ingrid M C Bakker; Marianna R Bevova; Zoltán Bochdanovits; Dorret I Boomsma; Eco J de Geus; Witte J G Hoogendijk; Brenda W Penninx; Patrizia Rizzu; Johannes H Smit; David Sondervan; Peter Heutink
A fine-mapping study of 7 top scoring genes from a GWAS for major depressive disorder.
PloS one 2012;7(5):e37384.
2012: Javier Simón-Sánchez; Andrew B Singleton; Nigel Williams; Nicholas W Wood; Michael A Nalls; Claudia Schulte; Alexis Brice; Thomas Gasser; John Hardy; Peter Heutink; Peter Holmans; Laura L Kilarski; Maria Martinez; Huw R Morris
Cooperative genome-wide analysis shows increased homozygosity in early onset Parkinson's disease.
PloS one 2012;7(3):e28787.
2012: Manuel Baron; Zoltan Bochdanovits; Isabel Gobernado; Estrella Gomez-Tortosa; Peter Heutink; David G Munoz; Alberto Rabano; Adriano Jimenez-Escrig
Extended kindred with recessive late-onset Alzheimer disease maps to locus 8p22-p21.2: a genome-wide linkage analysis.
Alzheimer disease and associated disorders 2012;26(1):91-5.
2012: Shushant Jain; Ronald E van Kesteren; Peter Heutink
High content screening in neurodegenerative diseases.
Journal of visualized experiments : JoVE 2012;(59):e3452.
2012: Lonneke M L de Lau; Peter Heutink; Johan Marinus; Dagmar Verbaan; Jacobus J van Hilten
Catechol-O-methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(1):132-5.
2012: Kin Mok; Gabriele Mora; Huw R Morris; Karen E Morrison; Liisa Myllykangas; Michael A Nalls; Richard W Orrell; Terhi Peuralinna; Stuart Pickering-Brown; Rosa Rademakers; Gabriella Restagno; Pamela Sara Rollinson; Jennifer C Schymick; Aleksey Shatunov; Pamela J Shaw; Javier Simón-Sánchez; Pentti J Tienari; Bryan Joseph Traynor; John C van Swieten; Adrian Waite; Nigel Williams; Ammar Al-Chalabi; Bradley F Boeve; Adam L Boxer; Adriano Chio; Mariely DeJesus-Hernandez; Peter Heutink; Hannu Laaksovirta; Ian R Mackenzie; John Hardy
Chromosome 9 ALS and FTD locus is probably derived from a single founder.
Neurobiology of aging 2012;33(1):209.e3-8.
2011: J Kenneth Baillie; Mark W Barnett; Paul M Brennan; piero carninci; Fioravante De Sapio; Mark Fell; Thomas C Freeman; Daniel J Gerhardt; Stefano Gustincich; Peter Heutink; David A Hume; Jeffrey A Jeddeloh; John S Mattick; Richmond Todd; Patrizia Rizzu; Sarah Smith; Richard T Talbot; Kyle R Upton; Geoffrey J Faulkner
Somatic retrotransposition alters the genetic landscape of the human brain.
Nature 2011;479(7374):534-7.
2011: Shushant Jain; Patrizia Rizzu; David Sondervan; Zoltán Bochdanovits; Daniel Caminada; Peter Heutink
The complete automation of cell culture: improvements for high-throughput and high-content screening.
Journal of biomolecular screening 2011;16(8):932-9.
2011: Javier Simón-Sánchez; Jacobus J van Hilten; Bart van de Warrenburg; Bart Post; Henk W Berendse; Sampath Arepalli; Dena G Hernandez; Rob M A de Bie; Daan Velseboer; Hans Scheffer; Bas Bloem; Karin D van Dijk; Fernando Rivadeneira; Albert Hofman; André G Uitterlinden; Patrizia Rizzu; Zoltán Bochdanovits; Andrew Singleton; Peter Heutink
Genome-wide association study confirms extant PD risk loci among the Dutch.
European journal of human genetics : EJHG 2011;19(6):655-61.
2011: Linda van den Berg; Olivier van Beekum; Peter Heutink; Bram A Felius; Monique P M van de Heijning; Stefan Strijbis; Rosalina Spaendonk; Daniela Piancatelli; Keith M Garner; Rajae El Aouad; Erik Sistermans; Roger A H Adan; Henriette A Delemarre-Van De Waal
Melanocortin-4 receptor gene mutations in a Dutch cohort of obese children.
Obesity (Silver Spring, Md.) 2011;19(3):604-11.
2011: Conceição Bettencourt; Paula Coutinho; Teresa Cymbron; Peter Heutink; Teresa Kay; Mafalda Raposo; Patrizia Rizzu; Cristina Santos; João Vasconcelos; Manuela Lima
Parkinsonian phenotype in Machado-Joseph disease (MJD/SCA3): a two-case report.
BMC neurology 2011;11():131.
2010: Shushant Jain; Peter Heutink
From single genes to gene networks: high-throughput-high-content screening for neurological disease.
Neuron 2010;68(2):207-17.
2010: Linda van den Berg; Henriette Delemarre-van de Waal; Joan C Han; Bauke Ylstra; Paul Eijk; Maria Nesterova; Peter Heutink; Constantine A Stratakis
Investigation of a patient with a partial trisomy 16q including the fat mass and obesity associated gene (FTO): fine mapping and FTO gene expression study.
American journal of medical genetics. Part A 2010;152A(3):630-7.
2010: Dina Ruano; Gonçalo R Abecasis; Beate Glaser; Esther S Lips; L Niels Cornelisse; Arthur P H de Jong; David M Evans; George Davey Smith; Nicolas J Timpson; August B Smit; Peter Heutink; Matthijs Verhage; Danielle Posthuma
Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability.
American journal of human genetics 2010;86(2):113-25.
2010: Hilga katerberg; Danielle C Cath; Damiaan Denys; Peter Heutink; Annemiek Polman; Filip C W van Nieuwerburgh; Dieter L D Deforce; Zoltán Bochdanovits; Anton J L M van Balkom; Johan A Den Boer
The role of the COMT Val(158)Met polymorphism in the phenotypic expression of obsessive-compulsive disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(1):167-76.
2010: Marieke E Teeuw; Lidewij Henneman; Zoltan Bochdanovits; Peter Heutink; Dirk J Kuik; Martina C Cornel; Leo P ten Kate
Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of a case-control study.
BMC medical genetics 2010;11():113.
2010: Raluca Mihaescu; Symone B Detmar; Martina C Cornel; Wiesje M van der Flier; Peter Heutink; Elly M Hol; Marcel G M Olde Rikkert; Cornelia M van Duijn; A Cecile J W Janssens
Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives.
Journal of Alzheimer's disease : JAD 2010;20(4):967-80.
2009: Hilga katerberg; Christine Lochner; Danielle C Cath; Peter de Jonge; Zoltán Bochdanovits; Johanna C Moolman-Smook; Sîan M J Hemmings; Paul D Carey; Dan Stein; David Sondervan; Johan A den Boer; Anton J L M van Balkom; Annemiek Polman; Peter Heutink
The role of the brain-derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive-compulsive disorder (OCD).
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(8):1050-62.
2009: L Donker Kaat; A J W Boon; Asma Azmani; Wouter Kamphorst; Monique Breteler; B Anar; Peter Heutink; John C van Swieten
Familial aggregation of parkinsonism in progressive supranuclear palsy.
Neurology 2009;73(2):98-105.
2009: Z Bochdanovits; M Verhage; A B Smit; E J C de Geus; Danielle Posthuma; Dorret I Boomsma; B W J H Penninx; Witte J G Hoogendijk; Peter Heutink
Joint reanalysis of 29 correlated SNPs supports the role of PCLO/Piccolo as a causal risk factor for major depressive disorder.
Molecular psychiatry 2009;14(7):650-2.
2009: Luba Pardo; Zoltán Bochdanovits; Eco de Geus; Jouke J Hottenga; Patrick F Sullivan; Danielle Posthuma; Brenda W J H Penninx; Dorret Boomsma; Peter Heutink
Global similarity with local differences in linkage disequilibrium between the Dutch and HapMap-CEU populations.
European journal of human genetics : EJHG 2009;17(6):802-10.
2009: Sara Rollinson; Patrizia Rizzu; Stephen Sikkink; Matthew Baker; Nicola Halliwell; Julie Snowden; Bryan Joseph Traynor; Dina Ruano; Nigel J Cairns; Jonathan D Rohrer; Simon Mead; John Collinge; Martin N Rossor; Ela Akay; Rita Guerreiro; Rosa Rademakers; Karen E Morrison; Pau Pastor; Elena Alonso; Pablo Martinez-Lage; Neil Graff-Radford; David Neary; Peter Heutink; D M A Mann; John Van Swieten; Stuart Pickering-Brown
Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration.
Neurobiology of aging 2009;30(4):656-65.
2009: Patrick F Sullivan; E J C de Geus; G Willemsen; M R James; J H Smit; T Zandbelt; V Arolt; B T Baune; D Blackwood; S Cichon; W L Coventry; K Domschke; A Farmer; M Fava; S D Gordon; Q He; A C Heath; Peter Heutink; F Holsboer; W J Hoogendijk; J J Hottenga; Y Hu; M Kohli; Danyu Lin; S Lucae; D J Macintyre; W Maier; K A McGhee; Peter McGuffin; G W Montgomery; W J Muir; W A Nolen; M M Nöthen; R H Perlis; K Pirlo; D Posthuma; M Rietschel; P Rizzu; A Schosser; A B Smit; J W Smoller; J-Y Tzeng; R van Dyck; M Verhage; F G Zitman; N G Martin; N R Wray; dorret boomsma; B W J H Penninx
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo.
Molecular psychiatry 2009;14(4):359-75.
2009: A C Ludolph; J Kassubek; B G Landwehrmeyer; Eva-Maria Mandelkow; Eckhard Mandelkow; David J Burn; D Caparros-Lefebvre; Kirk A Frey; J G de Yebenes; T Gasser; Peter Heutink; G Höglinger; Z Jamrozik; Kurt A Jellinger; A Kazantsev; Hans A Kretzschmar; Anthony E Lang; I Litvan; J J Lucas; Patrick L McGeer; S Melquist; Wolfgang H Oertel; M Otto; D Paviour; T Reum; A Saint-Raymond; J C Steele; M Tolnay; H Tumani; J C van Swieten; M T Vanier; J-P Vonsattel; S Wagner; Zbigniew K Wszolek
Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2009;16(3):297-309.
2009: Maria G Macedo; Dagmar Verbaan; Yue Fang; Stephanie M van Rooden; Martine Visser; Burcu Anar; Antonella Uras; Justus L Groen; Patrizia Rizzu; Jacobus J van Hilten; Peter Heutink
Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(2):196-203.
2009: Javier Simón-Sánchez; Harro Seelaar; Zoltán Bochdanovits; Dorly J H Deeg; John C van Swieten; Peter Heutink
Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population.
PloS one 2009;4(10):e7494.
2009: Iraad F Bronner; Zoltán Bochdanovits; Patrizia Rizzu; Wouter Kamphorst; Rivka Ravid; John C van Swieten; Peter Heutink
Comprehensive mRNA expression profiling distinguishes tauopathies and identifies shared molecular pathways.
PloS one 2009;4(8):e6826.
2009: Zoltán Bochdanovits; Florencia M Gosso; Linda van den Berg; Patrizia Rizzu; Tinca JC Polderman; Luba M Pardo; Lorna M Houlihan; Michelle Luciano; John M Starr; Sarah E Harris; Ian J Deary; Eco J C de Geus; dorret boomsma; Peter Heutink; Danielle Posthuma
A Functional polymorphism under positive evolutionary selection in ADRB2 is associated with human intelligence with opposite effects in the young and the elderly.
Behavior genetics 2009;39(1):15-23.
2008: Dagmar Verbaan; S Boesveldt; Stephanie M van Rooden; Martine Visser; Johan Marinus; M G Macedo; Y Fang; Peter Heutink; H W Berendse; Jacobus J van Hilten
Is olfactory impairment in Parkinson disease related to phenotypic or genotypic characteristics?
Neurology 2008;71(23):1877-82.
2008: John C van Swieten; Peter Heutink
Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia.
Lancet neurology 2008;7(10):965-74.
2008: M Florencia Gosso; Eco J C De Geus; Tinca J C Polderman; Dorret I Boomsma; Peter Heutink; Danielle Posthuma
Catechol O-methyl transferase and dopamine D2 receptor gene polymorphisms: evidence of positive heterosis and gene-gene interaction on working memory functioning.
European journal of human genetics : EJHG 2008;16(9):1075-82.
2008: Hilga katerberg; Danielle C Cath; Marina A J Tijssen; Anton J L M van Balkom; Yvonne L C van de Leemput; Johan A Den Boer; Peter Heutink; Frank Baas
Screening of the epsilon sarcoglycan gene in Tourette syndrome and obsessive compulsive disorder.
Psychiatric genetics 2008;18(2):98.
2008: Zoltán Bochdanovits; Peter Heutink; Aad van der Vaart
Empirical assessment of the validity of the 'fundamental theorem of the HapMap' in the light of 'cryptic' tagging of multiple susceptibility loci.
European journal of human genetics : EJHG 2008;16(4):525-9.
2008: M Florencia Gosso; Eco J C De Geus; Tinca JC Polderman; Dorret I Boomsma; Peter Heutink; Danielle Posthuma
Common variants underlying cognitive ability: further evidence for association between the SNAP-25 gene and cognition using a family-based study in two independent Dutch cohorts.
Genes, brain, and behavior 2008;7(3):355-64.
2008: Dorret I Boomsma; Gonneke Willemsen; Patrick F Sullivan; Peter Heutink; Piet Meijer; David Sondervan; Cornelis Kluft; Guus Smit; Willem A Nolen; Frans Zitman; Johannes H Smit; Witte J Hoogendijk; Richard van Dyck; Eco J C De Geus; Brenda W J H Penninx
Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects.
European journal of human genetics : EJHG 2008;16(3):335-42.
2008: Zoltán Bochdanovits; David Sondervan; Sophie Perillous; Toos van Beijsterveldt; Dorret Boomsma; Peter Heutink
Genome-wide prediction of functional gene-gene interactions inferred from patterns of genetic differentiation in mice and men.
PloS one 2008;3(2):e1593.
2008: Marja W Wessels; Bianca de Graaf; Titia E Cohen-Overbeek; Silja E Spitaels; Lotte E de Groot-de Laat; Folkert J Ten Cate; Ingrid F M Frohn-Mulder; Ronald R de Krijger; Margot M Bartelings; Nienke Essed; Jury W Wladimiroff; Martinus F Niermeijer; Peter Heutink; Ben A Oostra; Dennis Dooijes; Aida M Bertoli Avella; Patrick J Willems
A new syndrome with noncompaction cardiomyopathy, bradycardia, pulmonary stenosis, atrial septal defect and heterotaxy with suggestive linkage to chromosome 6p.
Human genetics 2008;122(6):595-603.
2008: Dina Ruano; Yurii Aulchenko; antonio macedo; Maria J Soares; José Valente; Maria H Azevedo; Mara H Hutz; Clarissa Severino Gama; Maria Inês Lobato; Paulo Belmonte-de-Abreu; Ann B Goodman; Carlos N Pato; Peter Heutink; Joana Almeida Palha
Association of the gene encoding neurogranin with schizophrenia in males.
Journal of psychiatric research 2008;42(2):125-33.
2007: Muhammad Mahajnah; Dov Inbar; Steinmetz Adam; Peter Heutink; G J Breedveld; Rachel Straussberg
Benign hereditary chorea: clinical, neuroimaging, and genetic findings.
Journal of child neurology 2007;22(10):1231-4.
2007: Dina Ruano; antonio macedo; Maria J Soares; José Valente; Maria H Azevedo; Mara H Hutz; Clarissa Severino Gama; Maria Inês Lobato; Paulo Belmonte-de-Abreu; Ann B Goodman; Carlos N Pato; Maria João Saraiva; Peter Heutink; Joana Almeida Palha
Transthyretin: no association between serum levels or gene variants and schizophrenia.
Journal of psychiatric research 2007;41(8):667-72.
2007: Bart P C van de Warrenburg; Hans Scheffer; Peter Heutink; Bastiaan R Bloem
[Parkinson's disease(s): recent insight into genetic factors].
Nederlands tijdschrift voor geneeskunde 2007;151(30):1665-8.
2007: Dina Ruano; antonio macedo; Maria João Soares; José Valente; Maria Helena Azevedo; Carlos N Pato; Mara Helena Hutz; Clarissa Severino Gama; Maria Inês Lobato; Paulo Belmonte-de-Abreu; Peter Heutink; Joana Almeida Palha
Family-based and case-control studies reveal no association of lipocalin-type prostaglandin D2 synthase with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(5):642-6.
2007: Fan Liu; Alejandro Arias-Vásquez; Kristel Sleegers; Yurii Aulchenko; Manfred Kayser; Pascual Sanchez-Juan; Bing-Jian Feng; Aida M Bertoli Avella; John C van Swieten; Tatiana I Axenovich; Peter Heutink; Christine Van Broeckhoven; Ben A Oostra; C.M. Duijn
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population.
American journal of human genetics 2007;81(1):17-31.
2007: Eco J C De Geus; Dennis van't Ent; Saskia P A Wolfensberger; Peter Heutink; Witte J G Hoogendijk; Dorret I Boomsma; Dick J Veltman
Intrapair differences in hippocampal volume in monozygotic twins discordant for the risk for anxiety and depression.
Biological psychiatry 2007;61(9):1062-71.
2007: Nitzan Mekel-Bobrov; Danielle Posthuma; Sandra L Gilbert; Penelope Lind; M Florencia Gosso; Michelle Luciano; Sarah E Harris; Timothy Bates; Tinca J C Polderman; lawrence whalley; Helen Fox; John M Starr; Patrick D Evans; Grant W Montgomery; Croydon Fernandes; Peter Heutink; Nicholas G Martin; Dorret I Boomsma; Ian J Deary; Margaret J Wright; Eco J C De Geus; Bruce T Lahn
The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence.
Human molecular genetics 2007;16(6):600-8.
2007: Carol F Lippa; J E Duda; Murray Grossman; Howard I Hurtig; Dag Aarsland; Bradley Boeve; David J Brooks; dennis dickson; Bruno Dubois; M Emre; Stanley Fahn; J M Farmer; Douglas Galasko; James E Galvin; Christopher G Goetz; John H Growdon; Katrina Gwinn-Hardy; John Hardy; Peter Heutink; Takeshi Iwatsubo; K Kosaka; Virginia M-Y Lee; James B Leverenz; Eliezer Masliah; Ian G McKeith; Robert L Nussbaum; C Warren Olanow; B M Ravina; Andrew Singleton; Caroline M Tanner; John Q Trojanowski; Zbigniew K Wszolek
DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers.
Neurology 2007;68(11):812-9.
2007: Iraad F Bronner; Patrizia Rizzu; Harro Seelaar; Saskia E van Mil; Burcu Anar; Asma Azmani; Laura Donker Kaat; Sonia M Rosso; Peter Heutink; John C van Swieten
Progranulin mutations in Dutch familial frontotemporal lobar degeneration.
European journal of human genetics : EJHG 2007;15(3):369-74.
2007: Florencia M Gosso; Eco J C De Geus; Tinca J C Polderman; Dorret I Boomsma; Danielle Posthuma; Peter Heutink
Exploring the functional role of the CHRM2 gene in human cognition: results from a dense genotyping and brain expression study.
BMC medical genetics 2007;8():66.
2007: John C van Swieten; Iraad F Bronner; Asma Azmani; Lies-Anne Severijnen; Wouter Kamphorst; Rivka Ravid; Patrizia Rizzu; Rob Willemsen; Peter Heutink
The DeltaK280 mutation in MAP tau favors exon 10 skipping in vivo.
Journal of neuropathology and experimental neurology 2007;66(1):17-25.
2007: Hanne Lehn; Eske Derks; James J Hudziak; Peter Heutink; Toos C E M van Beijsterveldt; Dorret I Boomsma
Attention problems and attention-deficit/hyperactivity disorder in discordant and concordant monozygotic twins: evidence of environmental mediators.
Journal of the American Academy of Child and Adolescent Psychiatry 2007;46(1):83-91.
2006: Patrizia Rizzu; Saskia E van Mil; Burcu Anar; Sonia M Rosso; Laura Donker Kaat; Peter Heutink; John C van Swieten
CHMP2B mutations are not a cause of dementia in Dutch patients with familial and sporadic frontotemporal dementia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(8):944-6.
2006: Tinca J C Polderman; M Florencia Gosso; Danielle Posthuma; Toos C E M van Beijsterveldt; Peter Heutink; Frank C Verhulst; Dorret I Boomsma
A longitudinal twin study on IQ, executive functioning, and attention problems during childhood and early adolescence.
Acta neurologica Belgica 2006;106(4):191-207.
2006: M Florencia Gosso; Martine J Van Belzen; Eco J C De Geus; J C Polderman; Peter Heutink; Dorret I Boomsma; Danielle Posthuma
Association between the CHRM2 gene and intelligence in a sample of 304 Dutch families.
Genes, brain, and behavior 2006;5(8):577-84.
2006: A J M H Verkerk; D C Cath; Herma C van der Linde; J Both; Peter Heutink; Guido J Breedveld; Yurii Aulchenko; Ben A Oostra
Genetic and clinical analysis of a large Dutch Gilles de la Tourette family.
Molecular psychiatry 2006;11(10):954-64.
2006: M Florencia Gosso; Eco J C De Geus; Martine J Van Belzen; Tinca J C Polderman; Peter Heutink; Dorret I Boomsma; Danielle Posthuma
The SNAP-25 gene is associated with cognitive ability: evidence from a family-based study in two independent Dutch cohorts.
Molecular psychiatry 2006;11(9):878-86.
2006: Nan Zhong; Christina Y Kim; Patrizia Rizzu; Changiz Geula; Douglas R Porter; Emmanuel N Pothos; Ferdinando Squitieri; Peter Heutink; Jin Xu
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor.
The Journal of biological chemistry 2006;281(30):20940-8.
2006: Alice S Brooks; P A Leegwater; Grzegorz Burzynski; Patrick J Willems; Bianca de Graaf; I van Langen; Peter Heutink; Ben A Oostra; Robert M W Hofstra; Aida M Bertoli Avella
A novel susceptibility locus for Hirschsprung's disease maps to 4q31.3-q32.3.
Journal of medical genetics 2006;43(7):e35.
2006: Guido J Breedveld; I F M de Coo; Maarten H Lequin; W F M Arts; Peter Heutink; Douglas B Gould; Simon W M John; Ben A Oostra; Grazia M S Mancini
Novel mutations in three families confirm a major role of COL4A1 in hereditary porencephaly.
Journal of medical genetics 2006;43(6):490-5.
2006: Susan K Service; Joseph DeYoung; Maria Karayiorgou; J Louw Roos; Herman Pretorious; Gabriel Bedoya; Jorge Ospina; Andres Ruiz-Linares; antonio macedo; Joana Almeida Palha; Peter Heutink; Yurii Aulchenko; Ben Oostra; C.M. Duijn; Marjo-Riitta Jarvelin; Teppo Varilo; Lynette Peddle; Proton Rahman; Giovanna Piras; Maria Monne; Sarah Murray; Luana Galver; Leena Peltonen; Chiara Sabatti; ANDREW COLLINS; Nelson B Freimer
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies.
Nature genetics 2006;38(5):556-60.
2006: Douglas B Gould; F Campbell Phalan; Saskia E van Mil; John P Sundberg; Katayoun Vahedi; Pascale Massin; Marie-Germaine Bousser; Peter Heutink; Jeffrey H Miner; Elisabeth Tournier-Lasserve; Simon W M John
Role of COL4A1 in small-vessel disease and hemorrhagic stroke.
The New England journal of medicine 2006;354(14):1489-96.
2006: Marjo S van der Knaap; Leo M E Smit; Frederik Barkhof; Y A L Pijnenburg; Sonja Zweegman; Hans W M Niessen; Saskia Imhof; Peter Heutink
Neonatal porencephaly and adult stroke related to mutations in collagen IV A1.
Annals of neurology 2006;59(3):504-11.
2006: Aida M Bertoli Avella; Marieke C J Dekker; Yurii Aulchenko; Jeanine J Houwing-Duistermaat; Erik J Simons; Leon Testers; Luba M Pardo; Tessa Rademaker-Havinga; Pieter J L M Snijders; John C van Swieten; Vincenzo Bonifati; Peter Heutink; C.M. Duijn; Ben A Oostra
Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands.
Human genetics 2006;119(1-2):51-60.
2006: Esther Brusse; Inge de Koning; anneke maat-kievit; Ben A Oostra; Peter Heutink; John C van Swieten
Spinocerebellar ataxia associated with a mutation in the fibroblast growth factor 14 gene (SCA27): A new phenotype.
Movement disorders : official journal of the Movement Disorder Society 2006;21(3):396-401.
2006: Peter Heutink
PINK-1 and DJ-1--new genes for autosomal recessive Parkinson's disease.
Journal of neural transmission. Supplementum 2006;(70):215-9.
2006: Martine J Van Belzen; Peter Heutink
Genetic analysis of psychiatric disorders in humans.
Genes, brain, and behavior 2006;5 Suppl 2():25-33.
2005: Iraad F Bronner; B C ter Meulen; Asma Azmani; Lies-Anne Severijnen; Rob Willemsen; Wouter Kamphorst; Rivka Ravid; Peter Heutink; John C van Swieten
Hereditary Pick's disease with the G272V tau mutation shows predominant three-repeat tau pathology.
Brain : a journal of neurology 2005;128(Pt 11):2645-53.
2005: Marc C Meulener; Alexander J Whitworth; Cecilia E Armstrong-Gold; Patrizia Rizzu; Peter Heutink; Paul D Wes; Leo J Pallanck; Nancy M Bonini
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.
Current biology : CB 2005;15(17):1572-7.
2005: Douglas B Gould; F Campbell Phalan; Guido J Breedveld; Saskia E van Mil; Richard S Smith; John C Schimenti; Umberto Aguglia; Marjo S van der Knaap; Peter Heutink; Simon W M John
Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.
Science (New York, N.Y.) 2005;308(5725):1167-71.
2005: Aida M Bertoli-Avella; José L Giroud-Benitez; Ali Akyol; Egberto Barbosa; Onno Schaap; Herma C van der Linde; Emilia Martignoni; Leonardo Lopiano; Paolo Lamberti; Emiliana Fincati; Angelo Antonini; Fabrizio Stocchi; Pasquale Montagna; Ferdinando Squitieri; Paolo Marini; Giovanni Abbruzzese; Giovanni Fabbrini; Roberto Marconi; Alessio Dalla Libera; Giorgio Trianni; Marco Guidi; Antonio De Gaetano; Gustavo Boff Maegawa; Antonino De Leo; Virgilio Gallai; Giulia de Rosa; Nicola Vanacore; Giuseppe Meco; C.M. Duijn; Ben A Oostra; Peter Heutink; Vincenzo Bonifati
Novel parkin mutations detected in patients with early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2005;20(4):424-31.
2004: Chantal Hoekstra; Piet Meijer; Cornelis Kluft; Peter Heutink; Guus Smit; Eco J C De Geus; Johannes H Smit; Angelique van Bruggen; Grant W Montgomery; Dorret I Boomsma
Genetics of dizygotic twinning: a feasibility study for a biobank.
Twin research : the official journal of the International Society for Twin Studies 2004;7(6):556-63.
2004: Marieke C J Dekker; R J H Galjaard; Pieter J L M Snijders; Peter Heutink; Ben A Oostra; C.M. Duijn
Brachydactyly and short stature in a kindred with early-onset parkinsonism.
American journal of medical genetics. Part A 2004;130A(1):102-4.
2004: Vincenzo Bonifati; Ben A Oostra; Peter Heutink
Unraveling the pathogenesis of Parkinson's disease--the contribution of monogenic forms.
Cellular and molecular life sciences : CMLS 2004;61(14):1729-50.
2004: Kristel Sleegers; Gerwin Roks; Jessie Theuns; Yurii Aulchenko; Rosa Rademakers; Marc Cruts; Willem A van Gool; Christine Van Broeckhoven; Peter Heutink; Ben A Oostra; John C van Swieten; C.M. Duijn
Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.
Brain : a journal of neurology 2004;127(Pt 7):1641-9.
2004: Yurii Aulchenko; Peter Heutink; Ian Mackay; Aida M Bertoli Avella; Jan Pullen; Norbert Vaessen; Tessa Rademaker-Havinga; Lodewijk A Sandkuijl; Lon Cardon; Ben A Oostra; C.M. Duijn
Linkage disequilibrium in young genetically isolated Dutch population.
European journal of human genetics : EJHG 2004;12(7):527-34.
2004: Umberto Aguglia; Antonio Gambardella; Guido J Breedveld; RL Oliveri; Emilio Le Piane; Demetrio Messina; Aldo Quattrone; Peter Heutink
Suggestive evidence for linkage to chromosome 13qter for autosomal dominant type 1 porencephaly.
Neurology 2004;62(9):1613-5.
2004: Aida M Bertoli Avella; Ben A Oostra; Peter Heutink
Chasing genes in Alzheimer's and Parkinson's disease.
Human genetics 2004;114(5):413-38.
2004: L Donker Kaat; A J W Boon; Peter Heutink; John C van Swieten
[Progressive supranuclear palsy; an unusual form of parkinsonism].
Nederlands tijdschrift voor geneeskunde 2004;148(11):519-23.
2004: Marijke J van Baren; Peter Heutink
The PCR suite.
Bioinformatics (Oxford, England) 2004;20(4):591-3.
2004: Vincenzo Bonifati; Ben A Oostra; Peter Heutink
Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease.
Journal of molecular medicine (Berlin, Germany) 2004;82(3):163-74.
2004: Katja Hedrich; Ana Djarmati; Nora Schäfer; Robert Hering; Claudia Wellenbrock; Peter H Weiss; Rüdiger Hilker; Peter Vieregge; Laurie J Ozelius; Peter Heutink; Vincenzo Bonifati; Eberhard Schwinger; Anthony E Lang; J Noth; Susan Bressman; Peter P Pramstaller; Olaf Riess; Christine Klein
DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease.
Neurology 2004;62(3):389-94.
2004: John C van Swieten; Sonia M Rosso; Esther van Herpen; Wouter Kamphorst; Rivka Ravid; Peter Heutink
Phenotypic variation in frontotemporal dementia and parkinsonism linked to chromosome 17.
Dementia and geriatric cognitive disorders 2004;17(4):261-4.
2004: Johannes Prudlo; Burkhard Alber; Vera Kalscheuer; Klaus Roemer; Thomas Martin; Jörn S Dullinger; Helmut Sittinger; Stephan Niemann; Peter Heutink; Albert C Ludolph; Hilger H Ropers; Klaus Zang; Thomas Meyer
Chromosomal translocation t(18;21)(q23;q22.1) indicates novel susceptibility loci for frontotemporal dementia with ALS.
Annals of neurology 2004;55(1):134-8.
2004: Patrizia Rizzu; David A Hinkle; Victoria Zhukareva; Vincenzo Bonifati; Lies-Anne Severijnen; Daniel Martinez; Rivka Ravid; Wouter Kamphorst; james eberwine; Virginia M-Y Lee; John Q Trojanowski; Peter Heutink
DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia.
Annals of neurology 2004;55(1):113-8.
2003: Yurii Aulchenko; Norbert Vaessen; Peter Heutink; Jan Pullen; Pieter J L M Snijders; Albert Hofman; Lodewijk A Sandkuijl; Jeanine J Houwing-Duistermaat; Mark Edwards; Simon Bennett; Ben A Oostra; C.M. Duijn
A genome-wide search for genes involved in type 2 diabetes in a recently genetically isolated population from the Netherlands.
Diabetes 2003;52(12):3001-4.
2003: Pablo Ibáñez; Giuseppe De Michele; Vincenzo Bonifati; Ebba Lohmann; Stéphane Thobois; Pierre Pollak; Yves Agid; Peter Heutink; Alexandra Dürr; Alexis Brice
Screening for DJ-1 mutations in early onset autosomal recessive parkinsonism.
Neurology 2003;61(10):1429-31.
2003: Aida M Bertoli Avella; Jose L Giroud-Benitez; Vincenzo Bonifati; Eduardo Alvarez-Gonzalez; Luis Heredero-Baute; C.M. Duijn; Peter Heutink
Suggestive linkage to chromosome 19 in a large Cuban family with late-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003;18(11):1240-9.
2003: David Nicholl; Michael Greenstone; Carl Clarke; Patrizia Rizzu; Daniel Crooks; Alex Crowe; John Q Trojanowski; Virginia M-Y Lee; Peter Heutink
An English kindred with a novel recessive tauopathy and respiratory failure.
Annals of neurology 2003;54(5):682-6.
2003: Esther van Herpen; Sonia M Rosso; Lies-Anne Serverijnen; Hirotaka Yoshida; Guido J Breedveld; Raoul van de Graaf; Wouter Kamphorst; Rivka Ravid; Rob Willemsen; Dennis Dooijes; Danielle Majoor-Krakauer; Johan M Kros; R Anthony Crowther; Michel Goedert; Peter Heutink; John C van Swieten
Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315R.
Annals of neurology 2003;54(5):573-81.
2003: Rosa Rademakers; Bart Dermaut; Karin Peeters; Marc Cruts; Peter Heutink; Alison Goate; Christine Van Broeckhoven
Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in Western Europe.
Human mutation 2003;22(5):409-11.
2003: Maria G Macedo; Burcu Anar; Iraad F Bronner; Milena Cannella; Ferdinando Squitieri; Vincenzo Bonifati; André Hoogeveen; Peter Heutink; Patrizia Rizzu
The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes.
Human molecular genetics 2003;12(21):2807-16.
2003: Vincenzo Bonifati; Patrizia Rizzu; Ferdinando Squitieri; Elmar Krieger; Nicola Vanacore; John C van Swieten; Alexis Brice; C.M. Duijn; Ben A Oostra; Giuseppe Meco; Peter Heutink
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2003;24(3):159-60.
2003: Marieke C J Dekker; John C van Swieten; Jeanine J Houwing-Duistermaat; Pieter J L M Snijders; E Boeren; Albert Hofman; Monique Breteler; Peter Heutink; Ben A Oostra; C.M. Duijn
A clinical-genetic study of Parkinson's disease in a genetically isolated community.
Journal of neurology 2003;250(9):1056-62.
2003: Sonia M Rosso; Esther van Herpen; Y A L Pijnenburg; Niki S M Schoonenboom; Philip scheltens; Peter Heutink; John C van Swieten
Total tau and phosphorylated tau 181 levels in the cerebrospinal fluid of patients with frontotemporal dementia due to P301L and G272V tau mutations.
Archives of neurology 2003;60(9):1209-13.
2003: Sonia M Rosso; Laura Donker Kaat; Timo Baks; Marijke Joosse; Inge de Koning; Y A L Pijnenburg; Danielle De Jong; Dennis Dooijes; Wouter Kamphorst; Rivka Ravid; Martinus F Niermeijer; Frans Verheij; H P H Kremer; Philip scheltens; C.M. Duijn; Peter Heutink; John C van Swieten
Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study.
Brain : a journal of neurology 2003;126(Pt 9):2016-22.
2003: R J H Galjaard; Herma C van der Linde; Bert H J Eussen; Bert B A de Vries; Cokkie H Wouters; Ben A Oostra; Esther de Graaff; Peter Heutink
Isolated postaxial polydactyly type B with mosaicism of a submicroscopic unbalanced translocation leading to an extended phenotype in offspring.
American journal of medical genetics. Part A 2003;121A(2):168-73.
2003: Stephen Hague; Ekaterina Rogaeva; Dena Hernandez; Cindy Gulick; Andrew Singleton; Melissa Hanson; Janel Johnson; Roberto Weiser; Marisol Gallardo; Bernard Ravina; Katrina Gwinn-Hardy; Anthony Crawley; Peter St George-Hyslop; Anthony E Lang; Peter Heutink; Vincenzo Bonifati; John Hardy; Andrew Singleton
Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation.
Annals of neurology 2003;54(2):271-4.
2003: AK Mostert; PF Dijkstra; B R H Jansen; JR van Horn; Bianca de Graaf; Peter Heutink; Dick Lindhout
Familial multiple epiphyseal dysplasia due to a matrilin-3 mutation: further delineation of the phenotype including 40 years follow-up.
American journal of medical genetics. Part A 2003;120A(4):490-7.
2003: Fusun Duzcan; Mehmet Zencir; Fatma Ozdemir; G Ozan Cetin; Huseyin Bagci; Peter Heutink; Vincenzo Bonifati; Türker Sahiner
Familial influence on parkinsonism in a rural area of Turkey (Kizilcaboluk-Denizli): a community-based case-control study.
Movement disorders : official journal of the Movement Disorder Society 2003;18(7):799-804.
2003: Marieke C J Dekker; Vincenzo Bonifati; John C van Swieten; Nico Leenders; R J H Galjaard; Pieter J L M Snijders; Martin Horstink; Peter Heutink; Ben A Oostra; C.M. Duijn
Clinical features and neuroimaging of PARK7-linked parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2003;18(7):751-7.
2003: Annemieke J M H Verkerk; Carol A Mathews; Marijke Joosse; Bert H J Eussen; Peter Heutink; Ben A Oostra
CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder.
Genomics 2003;82(1):1-9.
2003: R J H Galjaard; Arie P T Smits; Joep H A M Tuerlings; Aagje G Bais; Aida M Bertoli Avella; Guido J Breedveld; Esther de Graaff; Ben A Oostra; Peter Heutink
A new locus for postaxial polydactyly type A/B on chromosome 7q21-q34.
European journal of human genetics : EJHG 2003;11(5):409-15.
2003: Armand Savioz; Beat M Riederer; Peter Heutink; Patrizia Rizzu; Markus Tolnay; Enikö Kövari; Alphonse Probst; Irène M Riederer; Constantin Bouras; Geneviève Leuba
Tau and neurofilaments in a family with frontotemporal dementia unlinked to chromosome 17q21-22.
Neurobiology of disease 2003;12(1):46-55.
2003: Vincenzo Bonifati; Patrizia Rizzu; Marijke J van Baren; Onno Schaap; Guido J Breedveld; Elmar Krieger; Marieke C J Dekker; Ferdinando Squitieri; Pablo Ibanez; Marijke Joosse; Jeroen W F van Dongen; Nicola Vanacore; John C van Swieten; Alexis Brice; Giuseppe Meco; C.M. Duijn; Ben A Oostra; Peter Heutink
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Science (New York, N.Y.) 2003;299(5604):256-9.
2003: Taizo Horikoshi; Naoto Endo; Minoru Shibata; Peter Heutink; Robert E Hill; Sumihare Noji
Disruption of the C7orf2/Lmbr1 genic region is associated with preaxial polydactyly in humans and mice.
Journal of bone and mineral metabolism 2003;21(1):1-4.
2003: John C van Swieten; Esther Brusse; Bianca de Graaf; Elmar Krieger; Raoul van de Graaf; Inge de Koning; anneke maat-kievit; Peter Leegwater; Dennis Dooijes; Ben A Oostra; Peter Heutink
A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebellar ataxia [corrected].
American journal of human genetics 2003;72(1):191-9.
2002: Omer T Njajou; Gerard de Jong; Bianca Berghuis; Norbert Vaessen; Pieter J L M Snijders; Jan P Goossens; John H P Wilson; Martijn H Breuning; Ben A Oostra; Peter Heutink; Lodewijk A Sandkuijl; C.M. Duijn
Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics.
Blood cells, molecules & diseases 2002;29(3):439-43.
2002: Aida M Bertoli Avella; B Marcheco Teruel; J J Llibre Rodriguez; N Gomez Viera; I Borrajero Martinez; E A Severijnen; Marijke Joosse; C.M. Duijn; Luis Heredero-Baute; Peter Heutink
A novel presenilin 1 mutation (L174 M) in a large Cuban family with early onset Alzheimer disease.
Neurogenetics 2002;4(2):97-104.
2002: Peter Heutink; Ben A Oostra
Gene finding in genetically isolated populations.
Human molecular genetics 2002;11(20):2507-15.
2002: Vincenzo Bonifati; Marieke C J Dekker; Nicola Vanacore; Giovanni Fabbrini; Ferdinando Squitieri; Roberto Marconi; Angelo Antonini; P Brustenghi; A Dalla Libera; Michele De Mari; Fabrizio Stocchi; P Montagna; V Gallai; Patrizia Rizzu; John C van Swieten; Ben A Oostra; C.M. Duijn; Giuseppe Meco; Peter Heutink
Autosomal recessive early onset parkinsonism is linked to three loci: PARK2, PARK6, and PARK7.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2002;23 Suppl 2():S59-60.
2002: Bert B A de Vries; Guido J Breedveld; Wout Deelen; Martijn H Breuning; Martinus F Niermeijer; Peter Heutink
Another family with nonspecific X-linked mental retardation (MRX78) maps to Xp11.4-p11.23.
American journal of medical genetics 2002;111(4):443-5.
2002: Guido J Breedveld; Alan K Percy; Marcy E MacDonald; Bert B A de Vries; C Yapijakis; Leon S Dure; E F Ippel; Lodewijk A Sandkuijl; Peter Heutink; W F M Arts
Clinical and genetic heterogeneity in benign hereditary chorea.
Neurology 2002;59(4):579-84.
2002: Yong Tian; Guido J Breedveld; Shangzhi Huang; Ben A Oostra; Peter Heutink; Wilson H Y Lo
Characterization of ZNF333, a novel double KRAB domain containing zinc finger gene on human chromosome 19p13.1.
Biochimica et biophysica acta 2002;1577(1):121-5.
2002: AK Mostert; PF Dijkstra; JR van Horn; B R H Jansen; Peter Heutink; Dick Lindhout
[Radiologische Besonderheiten einer bilateral vererblichen Mikro-Epiphysendysplasie - deutliche Entität einer Skelettdysplasie].
RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 2002;174(7):887-92.
2002: S M Rosso; Gerwin Roks; Marc Cruts; Christine Van Broeckhoven; Peter Heutink; C.M. Duijn; John C van Swieten
Apolipoprotein E4 in the temporal variant of frontotemporal dementia.
Journal of neurology, neurosurgery, and psychiatry 2002;72(6):820.
2002: Laura A Lettice; Taizo Horikoshi; Simon J H Heaney; Marijke J van Baren; Herma C van der Linde; Guido J Breedveld; Marijke Joosse; Nurten Akarsu; Ben A Oostra; Naoto Endo; Minoru Shibata; Mikio Suzuki; Eiichi Takahashi; Toshikatsu Shinka; Yutaka Nakahori; Dai Ayusawa; Kazuhiko Nakabayashi; Stephen W Scherer; Peter Heutink; Robert E Hill; Sumihare Noji
Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7548-53.
2002: Guido J Breedveld; Jeroen W F van Dongen; Cesare Danesino; Andrea Guala; Alan K Percy; Leon S Dure; Peter Harper; Lazarus P Lazarou; Herma C van der Linde; Marijke Joosse; Annette Grüters; Marcy E MacDonald; Bert B A de Vries; W F M Arts; Ben A Oostra; Heiko Krude; Peter Heutink
Mutations in TITF-1 are associated with benign hereditary chorea.
Human molecular genetics 2002;11(8):971-9.
2002: Norbert Vaessen; Joop A M J L Janssen; Peter Heutink; Albert Hofman; Steven W J Lamberts; Ben A Oostra; Huibert A P Pols; C.M. Duijn
Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight.
Lancet 2002;359(9311):1036-7.
2002: Marijke J van Baren; Herma C van der Linde; Guido J Breedveld; Willy M Baarends; Patrizia Rizzu; Esther de Graaff; Ben A Oostra; Peter Heutink
A double RING-H2 domain in RNF32, a gene expressed during sperm formation.
Biochemical and biophysical research communications 2002;292(1):58-65.
2002: Hongshan Zhao; Yong Tian; Guido Breedveld; Shangzhi Huang; Ying Zou; Jue Y; Jinghua Chai; Hui Li; Mingyue Li; Ben A Oostra; Wilson H Y Lo; Peter Heutink
Postaxial polydactyly type A/B (PAP-A/B) is linked to chromosome 19p13.1-13.2 in a Chinese kindred.
European journal of human genetics : EJHG 2002;10(3):162-6.
2002: Omer T Njajou; Norbert Vaessen; Ben A Oostra; Peter Heutink; C.M. Duijn
The hemochromatosis N144H mutation of SLC11A3 gene in patients with type 2 diabetes.
Molecular genetics and metabolism 2002;75(3):290-1.
2002: Sonia M Rosso; Esther van Herpen; Wout Deelen; Wouter Kamphorst; Lies-Anne Severijnen; Rob Willemsen; Rivka Ravid; Martinus F Niermeijer; Dennis Dooijes; Michael J Smith; Michel Goedert; Peter Heutink; John C van Swieten
A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's disease.
Annals of neurology 2002;51(3):373-6.
2002: Norbert Vaessen; Peter Heutink; Jeanine J Houwing-Duistermaat; Pieter J L M Snijders; Tessa Rademaker-Havinga; Leon Testers; Manou R Batstra; Lodewijk A Sandkuijl; C.M. Duijn; Ben A Oostra
A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands.
Diabetes 2002;51(3):856-9.
2002: Vincenzo Bonifati; Guido J Breedveld; Ferdinando Squitieri; Nicola Vanacore; Pierluigi Brustenghi; Biswadjiet S Harhangi; Pasquale Montagna; Milena Cannella; Giovanni Fabbrini; Patrizia Rizzu; C.M. Duijn; Ben A Oostra; Giuseppe Meco; Peter Heutink
Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset.
Annals of neurology 2002;51(2):253-6.
2002: AK Mostert; B R H Jansen; PF Dijkstra; E Wesby-van Swaay; JR van Horn; Peter Heutink; Dick Lindhout
Bilateral hereditary micro-epiphyseal dysplasia: further delineation of the phenotype with 40 years follow-up.
International orthopaedics 2002;26(3):188-93.
2001: Sonia M Rosso; Wouter Kamphorst; Bianca de Graaf; Rob Willemsen; Rivka Ravid; Martinus F Niermeijer; Maria Grazia Spillantini; Peter Heutink; John C van Swieten
Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21-22.
Brain : a journal of neurology 2001;124(Pt 10):1948-57.
2001: R J H Galjaard; N Kostakoglu; Jeannette Hoogeboom; Guido J Breedveld; Herma C van der Linde; Steven E R Hovius; Ben A Oostra; Lodewijk A Sandkuijl; A N Akarsu; Peter Heutink
X-linked recessive inheritance of radial ray deficiencies in a family with four affected males.
European journal of human genetics : EJHG 2001;9(9):653-8.
2001: C.M. Duijn; Marieke C J Dekker; Vincenzo Bonifati; R J H Galjaard; Jeanine J Houwing-Duistermaat; Pieter J L M Snijders; Leon Testers; Guido J Breedveld; Martin Horstink; Lodewijk A Sandkuijl; John C van Swieten; Ben A Oostra; Peter Heutink
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.
American journal of human genetics 2001;69(3):629-34.
2001: Omer T Njajou; Norbert Vaessen; Marijke Joosse; B Berghuis; Jeroen W F van Dongen; Martijn H Breuning; Pieter J L M Snijders; W P Rutten; Lodewijk A Sandkuijl; Ben A Oostra; C.M. Duijn; Peter Heutink
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis.
Nature genetics 2001;28(3):213-4.
2001: Joost P H Drenth; W H Finley; Guido J Breedveld; Leon Testers; J J Michiels; G Guillet; Alain Taieb; R L Kirby; Peter Heutink
The primary erythermalgia-susceptibility gene is located on chromosome 2q31-32.
American journal of human genetics 2001;68(5):1277-82.
2001: Biswadjiet S Harhangi; Ben A Oostra; Peter Heutink; C.M. Duijn; Albert Hofman; Monique Breteler
CYP2D6 polymorphism in Parkinson's disease: the Rotterdam Study.
Movement disorders : official journal of the Movement Disorder Society 2001;16(2):290-3.
2001: Norbert Vaessen; Peter Heutink; Joop A M J L Janssen; Jacqueline C M Witteman; Leon Testers; Albert Hofman; Steven W J Lamberts; Ben A Oostra; Huibert A P Pols; C.M. Duijn
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction.
Diabetes 2001;50(3):637-42.
2001: Tomohiro Miyasaka; Maho Morishima-Kawashima; Rivka Ravid; Peter Heutink; J C van Swieten; Kazuo Nagashima; Yasuo Ihara
Molecular analysis of mutant and wild-type tau deposited in the brain affected by the FTDP-17 R406W mutation.
The American journal of pathology 2001;158(2):373-9.
2001: R J H Galjaard; L I van der Ham; N A Posch; PF Dijkstra; Ben A Oostra; Steven E R Hovius; E J Timmenga; GJ Sonneveld; A J Hoogeboom; Peter Heutink
Differences in complexity of isolated brachydactyly type C cannot be attributed to locus heterogeneity alone.
American journal of medical genetics 2001;98(3):256-62.
2001: HC Heus; A J M Luijsterburg; Marijke J van Baren; Guido J Breedveld; Marijke Joosse; Ingeborg M Nieuwenhuizen; Christl Vermeij-Keers; Ben A Oostra; Peter Heutink
Hemimelic extra toes and Hammer toe are distinct mutations that show a genetic interaction.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(1):77-9.
2001: Peter Ianakiev; Mark J Daly; sergio toledo; M G Cavalcanti; J C Neto; Elizabeth Silveira; A Freire-Maia; Peter Heutink; Michael W Kilpatrick; Petros Tsipouras
Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene.
American journal of human genetics 2001;68(1):38-45.
2000: Patrizia Rizzu; Marijke Joosse; Rivka Ravid; André Hoogeveen; Wouter Kamphorst; John C van Swieten; Rob Willemsen; Peter Heutink
Mutation-dependent aggregation of tau protein and its selective depletion from the soluble fraction in brain of P301L FTDP-17 patients.
Human molecular genetics 2000;9(20):3075-82.
2000: S M Rosso; Peter Heutink; Aad Tibben; M F Niermeijer; John C van Swieten
[New insights in frontotemporal dementia].
Nederlands tijdschrift voor geneeskunde 2000;144(33):1575-80.
2000: Peter Heutink
Untangling tau-related dementia.
Human molecular genetics 2000;9(6):979-86.
2000: Bert B A de Vries; W F M Arts; Guido J Breedveld; Jeannette Hoogeboom; Martinus F Niermeijer; Peter Heutink
Benign hereditary chorea of early onset maps to chromosome 14q.
American journal of human genetics 2000;66(1):136-42.
1999: Gerwin Roks; Bart Dermaut; Peter Heutink; Ann Julliams; Hubert Backhovens; M Van de Broeck; Sally Serneels; Albert Hofman; Christine Van Broeckhoven; C.M. Duijn; Marc Cruts
Mutation screening of the tau gene in patients with early-onset Alzheimer's disease.
Neuroscience letters 1999;277(2):137-9.
1999: Anne-Dorte Sperfeld; M B Collatz; H Baier; M Palmbach; Alexander Storch; Johannes Schwarz; K Tatsch; S Reske; M Joosse; Peter Heutink; Albert C Ludolph
FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation.
Annals of neurology 1999;46(5):708-15.
1999: Vincenzo Bonifati; Marijke Joosse; David Nicholl; Nicola Vanacore; P Bennett; Patrizia Rizzu; Giovanni Fabbrini; Roberto Marconi; Carlo Colosimo; Nicoletta Locuratolo; Fabrizio Stocchi; Ubaldo Bonuccelli; Michele De Mari; G Wenning; Peter Vieregge; Ben A Oostra; Giuseppe Meco; Peter Heutink
The tau gene in progressive supranuclear palsy: exclusion of mutations in coding exons and exon 10 splice sites, and identification of a new intronic variant of the disease-associated H1 haplotype in Italian cases.
Neuroscience letters 1999;274(1):61-5.
1999: John C van Swieten; M Stevens; Sonia M Rosso; Patrizia Rizzu; Marijke Joosse; Inge de Koning; Wouter Kamphorst; Rivka Ravid; Maria Grazia Spillantini; Peter Heutink
Phenotypic variation in hereditary frontotemporal dementia with tau mutations.
Annals of neurology 1999;46(4):617-26.
1999: Biswadjiet S Harhangi; Ben A Oostra; Peter Heutink; C.M. Duijn; Albert Hofman; Monique Breteler
N-acetyltransferase-2 polymorphism in Parkinson's disease: the Rotterdam study.
Journal of neurology, neurosurgery, and psychiatry 1999;67(4):518-20.
1999: S Froelich; Henry Houlden; Patrizia Rizzu; Sumi Chakraverty; Matt Baker; J Kwon; P Nowotny; A Isaacs; V Nowotny; E Wauters; Marijke J van Baren; Ben A Oostra; John Hardy; Lars Lannfelt; Alison Goate; Michael Hutton; Corinne Lendon; Peter Heutink
Construction of a detailed physical and transcript map of the FTDP-17 candidate region on chromosome 17q21.
Genomics 1999;60(2):129-36.
1999: M Kalff-Suske; A Wild; J Topp; M Wessling; E M Jacobsen; Dorothea Bornholdt; Hartmut Engel; H Heuer; Cora M Aalfs; Margreet G E M Ausems; R Barone; A Herzog; Peter Heutink; T Homfray; Gabriele Gillessen-Kaesbach; Rainer König; Jürgen Kunze; Peter Meinecke; D Müller; R Rizzo; S Strenge; andrea superti-furga; Karl-Heinz Grzeschik
Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome.
Human molecular genetics 1999;8(9):1769-77.
1999: HC Heus; A Hing; Marijke J van Baren; Marijke Joosse; Guido J Breedveld; J C Wang; A Burgess; H Donnis-Keller; C Berglund; J Zguricas; S W Scherer; J M Rommens; Ben A Oostra; Peter Heutink
A physical and transcriptional map of the preaxial polydactyly locus on chromosome 7q36.
Genomics 1999;57(3):342-51.
1999: Henry Houlden; Patrizia Rizzu; M Stevens; P de Knijff; C.M. Duijn; John C van Swieten; Peter Heutink; Jordi Perez-Tur; V Thomas; Matt Baker; H Morris; Martin N Rossor; J C Jannsen; Ronald C. Petersen; P Dodd; F Dark; Bradley Boeve; dennis dickson; Peter Davies; Stuart Pickering-Brown; D M A Mann; Jennifer Adamson; Timothy Lynch; Haydeh Payami; John Hardy
Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations.
Neuroscience letters 1999;260(3):193-5.
1999: Patrizia Rizzu; John C van Swieten; Marijke Joosse; M Hasegawa; M Stevens; Aad Tibben; Martinus F Niermeijer; M Hillebrand; Rivka Ravid; Ben A Oostra; Michel Goedert; C.M. Duijn; Peter Heutink
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands.
American journal of human genetics 1999;64(2):414-21.
1999: J Zguricas; HC Heus; E Morales-Peralta; Guido J Breedveld; B Kuyt; E F Mumcu; W Bakker; N Akarsu; S P Kay; Steven E R Hovius; L Heredero-Baute; Ben A Oostra; Peter Heutink
Clinical and genetic studies on 12 preaxial polydactyly families and refinement of the localisation of the gene responsible to a 1.9 cM region on chromosome 7q36.
Journal of medical genetics 1999;36(1):32-40.
1998: Maria Grazia Spillantini; R Anthony Crowther; Wouter Kamphorst; Peter Heutink; J C van Swieten
Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau.
The American journal of pathology 1998;153(5):1359-63.
1998: Michael Hutton; C L Lendon; P Rizzu; M Baker; S Froelich; H Houlden; S Pickering-Brown; S Chakraverty; A Isaacs; Andrew Grover; J Hackett; J Adamson; Sarah J Lincoln; dennis dickson; Peter Davies; Ronald C. Petersen; M Stevens; E de Graaff; E Wauters; J van Baren; M Hillebrand; M Joosse; J M Kwon; P Nowotny; L K Che; J Norton; John C Morris; L A Reed; John Q Trojanowski; Hans Basun; Lars Lannfelt; M Neystat; Stanley Fahn; F Dark; T Tannenberg; P R Dodd; N Hayward; J B Kwok; P R Schofield; A Andreadis; J Snowden; D Craufurd; David Neary; F Owen; B A Oostra; John Hardy; Alison Goate; J van Swieten; D M A Mann; T Lynch; Peter Heutink
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17.
Nature 1998;393(6686):702-5.
1998: M Stevens; C.M. Duijn; W Kamphorst; P de Knijff; Peter Heutink; W A van Gool; Philip scheltens; Rivka Ravid; B A Oostra; M F Niermeijer; John C van Swieten
Familial aggregation in frontotemporal dementia.
Neurology 1998;50(6):1541-5.
1998: J Zguricas; W F Bakker; HC Heus; Dick Lindhout; Peter Heutink; Steven E R Hovius
Genetics of limb development and congenital hand malformations.
Plastic and reconstructive surgery 1998;101(4):1126-35.
1998: Bernard Brais; Jean-Pierre Bouchard; Ya-Gang Xie; Daniel Rochefort; N Chrétien; Fernando M S Tomé; Ronald G Lafrenière; Johanna M Rommens; Eiichiro Uyama; O Nohira; Sergiu C Blumen; Amos D Korczyn; Peter Heutink; Jean Mathieu; André Duranceau; François Codère; M Fardeau; Guy Rouleau; A D Korcyn
Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy.
Nature genetics 1998;18(2):164-7.
1997: M Stevens; C.M. Duijn; P de Knijff; Christine Van Broeckhoven; Peter Heutink; B A Oostra; M F Niermeijer; John C van Swieten
Apolipoprotein E gene and sporadic frontal lobe dementia.
Neurology 1997;48(6):1526-9.
1997: Peter Heutink; M Stevens; Patrizia Rizzu; E Bakker; Johan M Kros; Aad Tibben; Martinus F Niermeijer; C.M. Duijn; Ben A Oostra; John C van Swieten
Hereditary frontotemporal dementia is linked to chromosome 17q21-q22: a genetic and clinicopathological study of three Dutch families.
Annals of neurology 1997;41(2):150-9.
1996: J Zguricas; Peter Heutink; L Heredero; J Deurloo; Ben A Oostra; P J Snijders; Dick Lindhout; Steven E R Hovius
Genetic aspects of polydactyly.
Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen 1996;28(4):171-5.
1996: Carel B Hoyng; Peter Heutink; L Testers; A Pinckers; August F Deutman; B A Oostra
Autosomal dominant central areolar choroidal dystrophy caused by a mutation in codon 142 in the peripherin/RDS gene.
American journal of ophthalmology 1996;121(6):623-9.
1995: Peter Heutink; Ben J van de Wetering; Andrew J Pakstis; Roger Kurlan; Paul Sandor; Ben A Oostra; Lodewijk A Sandkuijl
Linkage studies on Gilles de la Tourette syndrome: what is the strategy of choice?
American journal of human genetics 1995;57(2):465-73.
1995: Peter Heutink; Christl Vermeij-Keers; Ben A Oostra
The genetic background of craniosynostosis syndromes.
European journal of human genetics : EJHG 1995;3(5):312-23.
1994: Peter Heutink; T Haitjema; G J Breedveld; Bart Janssen; Lodewijk A Sandkuijl; Carola J M Bontekoe; C J Westerman; Ben A Oostra
Linkage of hereditary haemorrhagic telangiectasia to chromosome 9q34 and evidence for locus heterogeneity.
Journal of medical genetics 1994;31(12):933-6.
1994: J Zguricas; P J Snijders; Steven E R Hovius; Peter Heutink; Ben A Oostra; Dick Lindhout
Phenotypic analysis of triphalangeal thumb and associated hand malformations.
Journal of medical genetics 1994;31(6):462-7.
1994: Peter Heutink; J Zguricas; L van Oosterhout; G J Breedveld; L Testers; Lodewijk A Sandkuijl; P J Snijders; J Weissenbach; Dick Lindhout; Steven E R Hovius
The gene for triphalangeal thumb maps to the subtelomeric region of chromosome 7q.
Nature genetics 1994;6(3):287-92.
1994: Y Q Wu; Peter Heutink; Bert B A de Vries; Lodewijk A Sandkuijl; Ans M W van den Ouweland; Martinus F Niermeijer; H Galjaard; Edwin Reyniers; Patrick J Willems; D J J Halley
Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11.
Human molecular genetics 1994;3(1):167-71.
1994: Peter Heutink; EM van Schothorst; Andel G L van der Mey; A Bardoel; G Breedveld; J Pertijs; Lodewijk A Sandkuijl; Gert-Jan B van Ommen; Cees J Cornelisse; Ben A Oostra
Further localization of the gene for hereditary paragangliomas and evidence for linkage in unrelated families.
European journal of human genetics : EJHG 1994;2(3):148-58.
1993: Carola J M Bontekoe; Esther de Graaff; G J Breedveld; Ben A Oostra; Peter Heutink
Dinucleotide repeat polymorphism at D11S994 locus.
Human molecular genetics 1993;2(10):1747.
1993: Ben J van de Wetering; Peter Heutink
The genetics of the Gilles de la Tourette syndrome: a review.
The Journal of laboratory and clinical medicine 1993;121(5):638-45.
1993: N A van Biezen; R H Lekanne Deprez; A Thijs; Peter Heutink; Ben A Oostra; A H Geurts van Kessel; Ellen C Zwarthoff
Isolation and characterization of 25 unique DNA markers for human chromosome 22.
Genomics 1993;15(1):206-8.
1992: Peter Heutink; Andel G L van der Mey; Lodewijk A Sandkuijl; A P van Gils; A Bardoel; G J Breedveld; Marcel van Vliet; Gert-Jan B van Ommen; Cees J Cornelisse; Ben A Oostra
A gene subject to genomic imprinting and responsible for hereditary paragangliomas maps to chromosome 11q23-qter.
Human molecular genetics 1992;1(1):7-10.
1992: Peter Heutink; Ben J van de Wetering; G J Breedveld; Ben A Oostra
Genetic study on Tourette syndrome in The Netherlands.
Advances in neurology 1992;58():167-72.
1991: R H Lekanne Deprez; N A van Biezen; Peter Heutink; K R Boejharat; Annelies de Klein; A H Geurts van Kessel; Ellen C Zwarthoff
A new polymorphic probe on chromosome 22q: NB129 (D22S193).
Nucleic acids research 1991;19(3):687.
1991: R H Lekanne Deprez; N A van Biezen; Peter Heutink; K R Boejharat; Annelies de Klein; A H Geurts van Kessel; Ellen C Zwarthoff
A new polymorphic probe on chromosome 22: NB84 (D22S183).
Nucleic acids research 1991;19(3):687.
1991: R H Lekanne Deprez; N A van Biezen; Peter Heutink; K R Boejharat; Annelies de Klein; A H Geurts van Kessel; Ellen C Zwarthoff
A new polymorphic probe on chromosome 22: NB35 (D22S182).
Nucleic acids research 1991;19(3):686.
1991: R H Lekanne Deprez; N A van Biezen; Peter Heutink; K R Boejharat; Annelies de Klein; A H Geurts van Kessel; Ellen C Zwarthoff
A new polymorphic probe on chromosome 22: NB17 (D22S181).
Nucleic acids research 1991;19(3):686.
1991: Andrew J Pakstis; Peter Heutink; David L Pauls; Roger Kurlan; Ben J van de Wetering; James F Leckman; L A Sandkuyl; Judith R Kidd; G J Breedveld; C M Castiglione
Progress in the search for genetic linkage with Tourette syndrome: an exclusion map covering more than 50% of the autosomal genome.
American journal of human genetics 1991;48(2):281-94.
1991: Peter Heutink; L A Sandkuyl; Ben J van de Wetering; Ben A Oostra; J Weber; P Wilkie; E J Devor; Andrew J Pakstis; David L Pauls; K K Kidd
Linkage and Tourette syndrome.
Lancet 1991;337(8733):122-3.
1990: Peter Heutink; Ben J van de Wetering; G J Breedveld; J Weber; L A Sandkuyl; E J Devor; A Heiberg; Martinus F Niermeijer; Ben A Oostra
No evidence for genetic linkage of Gilles de la Tourette syndrome on chromosomes 7 and 18.
Journal of medical genetics 1990;27(7):433-6.
1988: W J Krone; CM Debouck; L G Epstein; Peter Heutink; R Meloen; Jaap Goudsmit
Natural antibodies to HIV-tat epitopes and expression of HIV-1 genes in vivo.
Journal of medical virology 1988;26(3):261-70.