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Jean-Paul Achkar

Research Profile

Disorders

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Gati A Goel; Ahmed Kandiel; Jean-Paul Achkar; Bret Lashner
Molecular pathways underlying IBD-associated colorectal neoplasia: therapeutic implications.
Tasneem Ahmed; Florian Rieder; Claudio Fiocchi; Jean-Paul Achkar
Pathogenesis of postoperative recurrence in Crohn's disease.
Craig R Homer; Amy L Richmond; Nancy A Rebert; Jean-Paul Achkar; Christine McDonald
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.

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All Publications

2011: Gati A Goel; Ahmed Kandiel; Jean-Paul Achkar; Bret Lashner
Molecular pathways underlying IBD-associated colorectal neoplasia: therapeutic implications.
The American journal of gastroenterology 2011;106(4):719-30.
2011: Tasneem Ahmed; Florian Rieder; Claudio Fiocchi; Jean-Paul Achkar
Pathogenesis of postoperative recurrence in Crohn's disease.
Gut 2011;60(4):553-62.
2010: Craig R Homer; Amy L Richmond; Nancy A Rebert; Jean-Paul Achkar; Christine McDonald
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.
Gastroenterology 2010;139(5):1630-41, 1641.e1-2.
2010: Genevieve B Melton; Ravi P Kiran; Victor W Fazio; J He; Bo Shen; John R Goldblum; Jean-Paul Achkar; Ian C Lavery; Feza H Remzi
Do preoperative factors predict subsequent diagnosis of Crohn's disease after ileal pouch-anal anastomosis for ulcerative or indeterminate colitis?
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 2010;12(10):1026-32.
2010: Brian C Allen; Mark E Baker; David M Einstein; Erick M Remer; Brian R Herts; Jean-Paul Achkar; William Davros; Eric Novak; Nancy A Obuchowski
Effect of altering automatic exposure control settings and quality reference mAs on radiation dose, image quality, and diagnostic efficacy in MDCT enterography of active inflammatory Crohn's disease.
AJR. American journal of roentgenology 2010;195(1):89-100.
2009: Richard R Sharp; Jean-Paul Achkar; Margaret A Brinich; Ruth M Farrell
Helping patients make informed choices about probiotics: a need for research.
The American journal of gastroenterology 2009;104(4):809-13.
2009: Mark E Baker; James Walter; Nancy A Obuchowski; Jean-Paul Achkar; David M Einstein; Joseph C Veniero; Jon Vogel; Luca Stocchi
Mural attenuation in normal small bowel and active inflammatory Crohn's disease on CT enterography: location, absolute attenuation, relative attenuation, and the effect of wall thickness.
AJR. American journal of roentgenology 2009;192(2):417-23.
2008: Genevieve B Melton; Victor W Fazio; Ravi P Kiran; Jin He; Ian C Lavery; Bo Shen; Jean-Paul Achkar; James M Church; Feza H Remzi
Long-term outcomes with ileal pouch-anal anastomosis and Crohn's disease: pouch retention and implications of delayed diagnosis.
Annals of surgery 2008;248(4):608-16.
2008: Ashish Atreja; Jean-Paul Achkar; Anil Jain; C Martin Harris; Bret A Lashner
Using technology to promote gastrointestinal outcomes research: a case for electronic health records.
The American journal of gastroenterology 2008;103(9):2171-8.
2008: Jean-Paul Achkar; Richard Duerr
The expanding universe of inflammatory bowel disease genetics.
Current opinion in gastroenterology 2008;24(4):429-34.
2007: Jean-Paul Achkar
Ulcerative colitis: responding to the challenges.
Cleveland Clinic journal of medicine 2007;74(9):657-60.
2007: Themistocles Dassopoulos; Geoffrey C Nguyen; Alain Bitton; Gillian P Bromfield; L Philip Schumm; Yahong Wu; Abdul Elkadri; Miguel Regueiro; Benjamin Siemanowski; Esther A Torres; Federico J Gregory; Sunanda V Kane; Laura E Harrell; Denis Franchimont; Jean-Paul Achkar; Anne Griffiths; Steven R Brant; John D Rioux; Kent D Taylor; Richard H Duerr; Mark S Silverberg; Judy H Cho; A Hillary Steinhart
Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC).
Inflammatory bowel diseases 2007;13(8):975-83.
2007: Zhenwen Zhao; Yijin Xiao; Paul Elson; Haiyan Tan; Sarah J Plummer; Michael Berk; Phyu P Aung; Ian C Lavery; Jean-Paul Achkar; Li Li; Graham Casey; Yan Xu
Plasma lysophosphatidylcholine levels: potential biomarkers for colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(19):2696-701.
2006: Jean-Paul Achkar; Themistocles Dassopoulos; Mark S Silverberg; Jeffrey A Tuvlin; Richard H Duerr; Steven R Brant; Katherine A Siminovitch; Deepa Reddy; Lisa Datta; Theodore M Bayless; Leilei Zhang; M. Michael Barmada; John D Rioux; A Hillary Steinhart; Robin S McLeod; Anne M Griffiths; Zane Cohen; Huiying Yang; Gillian P Bromfield; Phil Schumm; Stephen B Hanauer; Judy H Cho; Dan L Nicolae
Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus.
The American journal of gastroenterology 2006;101(3):572-80.
2006: Bo Shen; Victor W Fazio; Feza H Remzi; Aaron Brzezinski; Ana E Bennett; Rocio Lopez; Jeffrey P Hammel; Jean-Paul Achkar; Charles L Bevins; Ian C Lavery; Scott A Strong; Conor P Delaney; Wendy Liu; Marlene L Bambrick; Kerry K Sherman; Bret A Lashner
Risk factors for diseases of ileal pouch-anal anastomosis after restorative proctocolectomy for ulcerative colitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006;4(1):81-9; quiz 2-3.
2005: Bo Shen; Aaron Brzezinski; Victor W Fazio; Feza H Remzi; Jean-Paul Achkar; Ana E Bennett; K Sherman; Bret A Lashner
Maintenance therapy with a probiotic in antibiotic-dependent pouchitis: experience in clinical practice.
Alimentary pharmacology & therapeutics 2005;22(8):721-8.
2005: Ravi P Kiran; Bridget O'Brien-Ermlich; Jean-Paul Achkar; Victor W Fazio; Conor P Delaney
Management of peristomal pyoderma gangrenosum.
Diseases of the colon and rectum 2005;48(7):1397-403.
2005: Bo Shen; Victor W Fazio; Feza H Remzi; Conor P Delaney; Ana E Bennett; Jean-Paul Achkar; Aaron Brzezinski; Farah Khandwala; Wendy Liu; Marlene L Bambrick; Jane Bast; Bret A Lashner
Comprehensive evaluation of inflammatory and noninflammatory sequelae of ileal pouch-anal anastomoses.
The American journal of gastroenterology 2005;100(1):93-101.
2005: Jean-Paul Achkar; Mohammad Al-Haddad; Bret A Lashner; Feza H Remzi; Aaron Brzezinski; Bo Shen; Farah Khandwala; Victor Fazio
Differentiating risk factors for acute and chronic pouchitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(1):60-6.
2004: Bo Shen; Victor W Fazio; Feza H Remzi; Conor P Delaney; Jean-Paul Achkar; Anna Bennett; Farah Khandwala; Aaron Brzezinski; Jhony Doumit; Wendy Liu; Bret A Lashner
Endoscopic balloon dilation of ileal pouch strictures.
The American journal of gastroenterology 2004;99(12):2340-7.
2004: Tyler Stevens; Jean-Paul Achkar; Kirk Easley; Aaron Brzezinski; Bret A Lashner
Azathioprine formulation optimizes metabolite profile in inflammatory bowel disease.
Alimentary pharmacology & therapeutics 2004;20(6):601-6.
2004: M. Michael Barmada; Steven R Brant; Dan L Nicolae; Jean-Paul Achkar; Carolien I Panhuysen; Theodore M Bayless; Judy H Cho; Richard H Duerr
A genome scan in 260 inflammatory bowel disease-affected relative pairs.
Inflammatory bowel diseases 2004;10(5):513-20.
2004: Bo Shen; Bret A Lashner; Ana E Bennett; Feza H Remzi; Aaron Brzezinski; Jean-Paul Achkar; Jane Bast; Marlene L Bambrick; Victor W Fazio
Treatment of rectal cuff inflammation (cuffitis) in patients with ulcerative colitis following restorative proctocolectomy and ileal pouch-anal anastomosis.
The American journal of gastroenterology 2004;99(8):1527-31.
2004: Jean-Paul Achkar; Tyler Stevens; Kirk Easley; Aaron Brzezinski; Douglas L Seidner; Bret A Lashner
Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel disease.
Inflammatory bowel diseases 2004;10(4):339-45.
2004: Jason M Wolf; Jean-Paul Achkar; Bret A Lashner; Conor P Delaney; Robert E Petras; John R Goldblum; Jason Connor; Feza H Remzi; Victor W Fazio
Afferent limb ulcers predict Crohn's disease in patients with ileal pouch-anal anastomosis.
Gastroenterology 2004;126(7):1686-91.
2004: Mansour A Parsi; Bo Shen; Jean-Paul Achkar; Feza F Remzi; John R Goldblum; James Boone; Dahai Lin; Jason Connor; Victor W Fazio; Bret A Lashner
Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis.
Gastroenterology 2004;126(5):1280-6.
2004: Mansour A Parsi; Bret A Lashner; Jean-Paul Achkar; Jason Connor; Aaron Brzezinski
Type of fistula determines response to infliximab in patients with fistulous Crohn's disease.
The American journal of gastroenterology 2004;99(3):445-9.
2004: M. Michael Barmada; Steven R Brant; Dan L Nicolae; Jean-Paul Achkar; Carolien I Panhuysen; Theodore M Bayless; Judy H Cho; Richard H Duerr
A genome scan in 260 inflammatory bowel disease-affected relative pairs.
Inflammatory bowel diseases 2004;10(1):15-22.
2004: Amir Karban; Toshihiko Okazaki; Carolien I Panhuysen; Thomas Gallegos; James J Potter; Joan E Bailey-Wilson; Mark S Silverberg; Richard H Duerr; Judy H Cho; Peter K Gregersen; Yuqiong Wu; Jean-Paul Achkar; Themistocles Dassopoulos; Esteban Mezey; Theodore M Bayless; Franklin J Nouvet; Steven R Brant
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis.
Human molecular genetics 2004;13(1):35-45.
2003: Steven R Brant; Carolien I Panhuysen; Dan L Nicolae; Deepthi M Reddy; Denise K Bonen; Reda Karaliukas; Leilei Zhang; Eric Swanson; Lisa Datta; Thomas Moran; Geoffrey Ravenhill; Richard H Duerr; Jean-Paul Achkar; Amir Karban; Judy H Cho
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.
American journal of human genetics 2003;73(6):1282-92.
2003: Bo Shen; Kenneth M Shermock; Victor W Fazio; Jean-Paul Achkar; Aaron Brzezinski; Charles L Bevins; Marlene L Bambrick; Feza H Remzi; Bret A Lashner
A cost-effectiveness analysis of diagnostic strategies for symptomatic patients with ileal pouch-anal anastomosis.
The American journal of gastroenterology 2003;98(11):2460-7.
2003: Steven R Brant; Michael F Picco; Jean-Paul Achkar; Theodore M Bayless; Sunanda V Kane; Aaron Brzezinski; Franklin J Nouvet; Denise K Bonen; Amir Karban; Themistocles Dassopoulos; Reda Karaliukas; Terri H beaty; Stephen B Hanauer; Richard H Duerr; Judy H Cho
Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes.
Inflammatory bowel diseases 2003;9(5):281-9.
2003: Bo Shen; Jean-Paul Achkar; Jason Connor; Adrian Ormsby; Feza H Remzi; Charles L Bevins; Aaron Brzezinski; Marlene L Bambrick; Victor W Fazio; Bret A Lashner
Modified pouchitis disease activity index: a simplified approach to the diagnosis of pouchitis.
Diseases of the colon and rectum 2003;46(6):748-53.
2002: Richard H Duerr; M. Michael Barmada; Leilei Zhang; Jean-Paul Achkar; Judy H Cho; Stephen B Hanauer; Steven R Brant; Theodore M Bayless; Robert N Baldassano; Daniel E Weeks
Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage.
Human molecular genetics 2002;11(21):2599-606.
2002: Jean-Paul Achkar; M. Michael Barmada; Richard H Duerr
Perinuclear neutrophil antibodies are not markers for genetic susceptibility or indicators of genetic heterogeneity in familial ulcerative colitis.
The American journal of gastroenterology 2002;97(9):2343-9.
2002: Mansour A Parsi; Jean-Paul Achkar; Scott Richardson; Jeffry Katz; Jeffrey P Hammel; Bret A Lashner; Aaron Brzezinski
Predictors of response to infliximab in patients with Crohn's disease.
Gastroenterology 2002;123(3):707-13.
2002: Bo Shen; Jean-Paul Achkar; Bret A Lashner; Adrian Ormsby; Aaron Brzezinski; Edy E Soffer; Feza H Remzi; Charles L Bevins; Victor W Fazio
Irritable pouch syndrome: a new category of diagnosis for symptomatic patients with ileal pouch-anal anastomosis.
The American journal of gastroenterology 2002;97(4):972-7.
2001: Jean-Paul Achkar; Bo Shen
Medical management of postoperative complications of inflammatory bowel disease: pouchitis and Crohn's disease recurrence.
Current gastroenterology reports 2001;3(6):484-90.
2001: Bo Shen; Jean-Paul Achkar; Bret A Lashner; Adrian Ormsby; Feza H Remzi; Aaron Brzezinski; Charles L Bevins; Marlene L Bambrick; Douglas L Seidner; Victor W Fazio
A randomized clinical trial of ciprofloxacin and metronidazole to treat acute pouchitis.
Inflammatory bowel diseases 2001;7(4):301-5.
2001: Bo Shen; Jean-Paul Achkar; Bret A Lashner; Adrian Ormsby; Feza H Remzi; Charles L Bevins; Aaron Brzezinski; Robert E Petras; Victor W Fazio
Endoscopic and histologic evaluation together with symptom assessment are required to diagnose pouchitis.
Gastroenterology 2001;121(2):261-7.
2001: Yasunori Ogura; Denise K Bonen; Naohiro Inohara; Dan L Nicolae; Felicia F Chen; R Ramos; H Britton; Thomas Moran; R Karaliuskas; Richard H Duerr; Jean-Paul Achkar; Steven R Brant; Theodore M Bayless; Barbara S Kirschner; Stephen B Hanauer; Gabriel Nuñez; Judy H Cho
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.
Nature 2001;411(6837):603-6.
2000: Edy E Soffer; KR Kongara; Jean-Paul Achkar; J Gannon
Colonic motor function in humans is not affected by gender.
Digestive diseases and sciences 2000;45(7):1281-4.
2000: Jean-Paul Achkar; Stephen B Hanauer
Medical therapy to reduce postoperative Crohn's disease recurrence.
The American journal of gastroenterology 2000;95(5):1139-46.
1998: Jean-Paul Achkar; Victor R Araya; Richard L Baron; J W Marsh; Igor Dvorchik; Jorge Rakela
Undetected hepatocellular carcinoma: clinical features and outcome after liver transplantation.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1998;4(6):477-82.