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Toshifumi Hibi

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Tadakazu Hisamatsu; Toshifumi Hibi
Innate immunity in the pathogenesis of inflammatory bowel disease.
Makoto Naganuma; Atsushi Sakuraba; Toshifumi Hibi
Ulcerative colitis: prevention of relapse.
Kazuaki Yoneno; Tadakazu Hisamatsu; Riko Ichikawa; Nobuhiko Kamada; Takanori Kanai; Mina T Kitazume; Kazutaka Koganei; Katsuyoshi Matsuoka; Maiko Mori; Yuka Namikawa; Toshiro Sato; Katsuyoshi Shimamura; Akira Sugita; Michihide Uo; Toshifumi Hibi
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.

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All Publications

2013: Tadakazu Hisamatsu; Toshifumi Hibi
Innate immunity in the pathogenesis of inflammatory bowel disease.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2013;110(5):753-63.
2013: Makoto Naganuma; Atsushi Sakuraba; Toshifumi Hibi
Ulcerative colitis: prevention of relapse.
Expert review of gastroenterology & hepatology 2013;7(4):341-51.
2013: Kazuaki Yoneno; Tadakazu Hisamatsu; Riko Ichikawa; Nobuhiko Kamada; Takanori Kanai; Mina T Kitazume; Kazutaka Koganei; Katsuyoshi Matsuoka; Maiko Mori; Yuka Namikawa; Toshiro Sato; Katsuyoshi Shimamura; Akira Sugita; Michihide Uo; Toshifumi Hibi
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.
Immunology 2013;139(1):19-29.
2013: Juntaro Matsuzaki; Hideki Mori; Sawako Okada; Shigeo Okuda; Hidekazu Suzuki; Toru Takebayashi; Akihiro Tanimoto; Hajime Higuchi; Kenro Hirata; Shigenari Hozawa; Sachio Kuribayashi; Tatsuhiro Masaoka; Keiko Asakura; Seiichiro Fukuhara; Toshifumi Hibi
Biliary findings assist in predicting enlargement of intraductal papillary mucinous neoplasms of the pancreas.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2013;11(5):548-54.
2013: Yoshimasa Saito; Hidekazu Suzuki; Hitoshi Tsugawa; Sana Hibino; Kenro Hirata; Hiroyuki Imaeda; Yae Kanai; Juntaro Matsuzaki; Hidetsugu Saito; Toshifumi Hibi
The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells.
International journal of cancer. Journal international du cancer 2013;132(8):1751-60.
2013: Yuji Nakamura; Keita Saeki; Hidetsugu Saito; Takahiro Suzuki; Miho Takabe; Toshiaki Teratani; Yoshiyuki Yamagishi; Hirotoshi Ebinuma; Hajime Higuchi; Tadakazu Hisamatsu; Shigenari Hozawa; Junichiro Irie; Hiroshi Itoh; Takanori Kanai; Yohei Mikami; Naoteru Miyata; Jun Miyoshi; Nobuhiro Nakamoto; Toshifumi Hibi
CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.
American journal of physiology. Gastrointestinal and liver physiology 2013;304(8):G700-7.
2013: Kenro Hirata; Eisuke Iwasaki; Tatsuhiro Masaoka; Juntaro Matsuzaki; Toshihiro Nishizawa; Sawako Okada; Yoshimasa Saito; Hidekazu Suzuki; Seiichiro Fukuhara; Toshifumi Hibi
Improvement of reflux symptom related quality of life after Helicobacter pylori eradication therapy.
Journal of clinical biochemistry and nutrition 2013;52(2):172-8.
2013: Tadakazu Hisamatsu; Takanori Kanai; Katsuyoshi Matsuoka; Yohei Mikami; Kazuaki Yoneno; Toshifumi Hibi
Immune aspects of the pathogenesis of inflammatory bowel disease.
Pharmacology & therapeutics 2013;137(3):283-97.
2013: Tomohisa Sujino; Hirotoshi Ebinuma; Yuuichirou Hayashi; Naoki Hosoe; Hiroyuki Imaeda; Takanori Kanai; Makio Mukai; Haruhiko Ogata; Susumu Okamoto; Toshifumi Hibi
Epstein-barr virus-associated gastritis: a case report.
Digestive diseases and sciences 2013;58(3):883-6.
2013: Tetsuro Takayama; Tomoharu Yajima; Tadakazu Hisamatsu; Yasushi Iwao; Takanaori Kanai; Katsuyoshi Matsuoka; Yohei Mikami; Haruhiko Ogata; Susumu Okamoto; Tomohisa Sujino; Toshifumi Hibi
Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy.
Journal of Crohn's & colitis 2013;7(2):e49-54.
2013: Tango Handa; Atsushi Hayashi; Tadakazu Hisamatsu; Takanori Kanai; Atsuhiro Matsumoto; Yohei Mikami; Shinta Mizuno; Toshiro Sato; Tomohisa Sujino; Toshifumi Hibi
Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice.
Immunology letters 2013;150(1-2):123-9.
2013: Ayano Kabashima-Niibe; Shigeyuki Kawachi; Yuko Kitagawa; Yo Mabuchi; Yohei Masugi; Yumi Matsuzaki; Michiie Sakamoto; Hiromasa Takaishi; Masayuki Adachi; Koichi Aiura; Shinsuke Funakoshi; Yasuo Hamamoto; Hajime Higuchi; Toshifumi Hibi
Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cells.
Cancer science 2013;104(2):157-64.
2013: Manabu Nakashita; Hidekazu Suzuki; Takao Taki; Keita Uehara; Soichiro Miura; Tohru Mizushima; Hiroshi Nagata; Toshifumi Hibi
Attenuation of acetic acid-induced gastric ulcer formation in rats by glucosylceramide synthase inhibitors.
Digestive diseases and sciences 2013;58(2):354-62.
2013: Atsuhiro Matsumoto; Yohei Mikami; Nobuhiro Nakamoto; Hidetsugu Saito; Toshiro Sato; Hideo Yagita; Po-Sung Chu; Hirotoshi Ebinuma; Takanori Kanai; Toshifumi Hibi
IL-22-Producing RORγt-Dependent Innate Lymphoid Cells Play a Novel Protective Role in Murine Acute Hepatitis.
PloS one 2013;8(4):e62853.
2013: Tetsufumi Takahashi; Kanji Tsuchimoto; Takao Imai; Hideyuki Okano; Shinsuke Shibata; Hidekazu Suzuki; Yoshiaki Tabuchi; Toshifumi Hibi
Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain-containing m-Numb protein expression in regenerating gastric mucosa.
PloS one 2013;8(1):e53540.
2013: Toshihiro Nishizawa; Hidekazu Suzuki; Masayuki Suzuki; Masahiko Takahashi; Hiroshi Kaneko; Toshifumi Hibi
Effect of ursodeoxycholic acid and endoscopic sphincterotomy in long-term stenting for common bile duct stones.
Journal of gastroenterology and hepatology 2013;28(1):63-7.
2013: Yuki Hirano; Toshifumi Hibi; Masahiro Niihara; Tomohiko Nishi; Kenshi Omagari; Takashi Oyama; Yoshiro Saikawa; Hiroyuki Sako; Hidekazu Suzuki; Hiroya Takeuchi; Yuko Kitagawa
Minimally invasive surgery for esophageal epiphrenic diverticulum: the results of 133 patients in 25 published series and our experience.
Surgery today 2013;43(1):1-7.
2013: Erika Kuwahara; Yuji Nishiwaki; Keiko Asakura; Toshifumi Hibi; Nagamu Inoue; Mamoru Watanabe; Toru Takebayashi
Reply to the letter by A. M. Bianco et al. regarding ''Effects of family history on IBD characteristics in Japanese patients''.
Journal of gastroenterology 2013;48(1):145-6.
2013: Hideko Akagi; Shinsuke Funakoshi; Yasuo Hamamoto; Masayuki Adachi; Hajime Higuchi; Toru Igarashi; Motoko Izumiya; Ayano Kabashima; Takanori Kanai; Yutaka Kawakami; Hiroyuki Mizuguchi; Shoko Nakamura; Gen Sakai; Hidetoshi Sumimoto; Hiromasa Takaishi; Toshifumi Hibi
Suppression of myeloid cell leukemia-1 (Mcl-1) enhances chemotherapy-associated apoptosis in gastric cancer cells.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2013;16(1):100-10.
2012: Yuji Koike; Yohei Mikami; Nobuhiro Nakamoto; Yuji Nakamura; Masaru Nakano; Keita Saeki; Yoshiyuki Yamagishi; Hirotoshi Ebinuma; Takanori Kanai; Toshifumi Hibi
MyD88-dependent interleukin-10 production from regulatory CD11b⁺Gr-1(high) cells suppresses development of acute cerulein pancreatitis in mice.
Immunology letters 2012;148(2):172-7.
2012: Hitoshi Tsugawa; Masanori Hatakeyama; Kenro Hirata; Toshiya Hirayama; Juntaro Matsuzaki; Osamu Nagano; Hideyuki Saya; Hidekazu Suzuki; Toshifumi Hibi
Reactive oxygen species-induced autophagic degradation of Helicobacter pylori CagA is specifically suppressed in cancer stem-like cells.
Cell host & microbe 2012;12(6):764-77.
2012: Hidekazu Suzuki; Hitoshi Tsugawa; Toshihiro Nishizawa; Toshifumi Hibi
Molecular approaches and modern clinical strategies for the management of Helicobacter pylori infection in Japan.
The Keio journal of medicine 2012;61(4):109-19.
2012: Erika Ohkura; Hiroshi Serizawa; Kanji Tsuchimoto; Satoshi Tsunematsu; Noriaki Watanabe; Tomoharu Yajima; Yukako Kato; Naoki Kumagai; Masaru Nakano; Toshifumi Hibi
[A case of small intestine type steroid-naïve Crohn disease in which osteomalacia was diagnosed by fractures on the transcervical bone].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2012;109(12):2082-7.
2012: Eisuke Iwasaki; Sachiko Mogami; Hidekazu Suzuki; Toshifumi Hibi
Enhanced gastric ghrelin-induced c-Kit protein expression in rats with gastric outlet obstruction.
Digestive diseases and sciences 2012;57(12):3308-9.
2012: Kayoko Kimura; Katsuyoshi Matsuoka; Yohei Mikami; Shinta Mizuno; Toshiro Sato; Tomohisa Sujino; Tango Handa; Atsushi Hayashi; Tadakazu Hisamatsu; Takanori Kanai; Toshifumi Hibi
Dysregulated balance of retinoid-related orphan receptor γt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis.
Biochemical and biophysical research communications 2012;427(4):694-700.
2012: Sota Oguro; Hidetsugu Saito; Minoru Tanabe; Tomoki Tanaka; Keiko Asakura; Hirotoshi Ebinuma; Subaru Hashimoto; Masanori Inoue; Shigeyuki Kawachi; Yuko Kitagawa; Sachio Kuribayashi; Seishi Nakatsuka; Toshifumi Hibi
Short-term therapeutic effects of transcatheter arterial chemoembolization using miriplatin-lipiodol suspension for hepatocellular carcinoma.
Japanese journal of radiology 2012;30(9):735-42.
2012: Yuichi Ono; Tomohisa Sujino; Hiromasa Takaishi; Mamoru Watanabe; Atsushi Hayashi; Tadakazu Hisamatsu; Takanori Kanai; Yasumasa Kanai; Atsuhiro Matsumoto; Katsuyoshi Matsuoka; Yohei Mikami; Yasuhiro Nemoto; Haruhiko Ogata; Toshifumi Hibi
T-helper 17 and interleukin-17-producing lymphoid tissue inducer-like cells make different contributions to colitis in mice.
Gastroenterology 2012;143(5):1288-97.
2012: Naoki Hosoe; Riko Ichikawa; Hiroyuki Imaeda; Nagamu Inoue; Takanori Kanai; Manabu Nakashita; Rieko Bessho; Toshifumi Hibi; Tomohisa Sujino; Haruhiko Ogata
Comparison of patient acceptance of sodium phosphate versus polyethylene glycol plus sodium picosulfate for colon cleansing in Japanese.
Journal of gastroenterology and hepatology 2012;27(10):1617-22.
2012: Hiromasa Nakamizo; Hidekazu Suzuki; Hideo Yoshida; Hiroshi Kishikawa; Hirofumi Matsui; Soichiro Miura; Sachiko Mogami; Toshifumi Hibi
Transmural pressure loading enhances gastric mucosal cell proliferation.
Digestive diseases and sciences 2012;57(10):2545-54.
2012: Kengo Tomita; Junji Yamamoto; Hirokazu Yokoyama; Yohko Yoshida; Hirotoshi Ebinuma; Kazuo Hatsuse; Ryota Hokari; Rie Irie; Takanori Kanai; Chie Kurihara; Norikazu Mataki; Tohru Minamino; Soichiro Miura; Kiyoshi Nishiyama; Yoshikiyo Okada; Tetsuya Oshikawa; Hidetsugu Saito; Katsuyoshi Shimamura; Ippei Shimizu; Kazuo Sugiyama; Takahiro Suzuki; Toshiaki Teratani; Toshifumi Hibi
p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.
Journal of hepatology 2012;57(4):837-43.
2012: Yoshimasa Saito; Hidekazu Suzuki; Toshiki Taya; Hitoshi Tsugawa; Kenro Hirata; Juntaro Matsuzaki; Masafumi Nishizawa; Hidetsugu Saito; Toshifumi Hibi
Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs.
Biochemical and biophysical research communications 2012;426(1):33-7.
2012: Tomomitsu Doi; Atsushi Hayashi; Li Jun; Takanori Kanai; Yohei Mikami; Yuichi Ono; Tomohisa Sujino; Toshifumi Hibi
IgA plasma cells express the negative regulatory co-stimulatory molecule programmed cell death 1 ligand and have a potential tolerogenic role in the intestine.
Biochemical and biophysical research communications 2012;425(4):918-23.
2012: Gen Sakai; Hiromasa Takaishi; Tomoharu Yajima; Masayuki Adachi; Hideko Akagi; Shinsuke Funakoshi; Yasuo Hamamoto; Hajime Higuchi; Motoko Izumiya; Takanori Kanai; Takehiko Mori; Makio Mukai; Shoko Nakamura; Shinichiro Okamoto; Toshifumi Hibi
Colon neoplastic cells do not originate from bone marrow-derived cells after sex-mismatched bone marrow transplantation.
Anticancer research 2012;32(9):4097-103.
2012: Motoko Izumiya; Ayano Kabashima; Shoko Nakamura; Gen Sakai; Hiromasa Takaishi; Masayuki Adachi; Shinsuke Funakoshi; Yasuo Hamamoto; Hajime Higuchi; Toru Igarashi; Hideko Iizuka; Toshifumi Hibi
Chemoresistance is associated with cancer stem cell-like properties and epithelial-to-mesenchymal transition in pancreatic cancer cells.
Anticancer research 2012;32(9):3847-53.
2012: Toshihiro Nishizawa; Hidekazu Suzuki; Masayuki Suzuki; Masahiko Takahashi; Toshifumi Hibi
Proton pump inhibitor-amoxicillin-clarithromycin versus proton pump inhibitor-amoxicillin-metronidazole as first-line Helicobacter pylori eradication therapy.
Journal of clinical biochemistry and nutrition 2012;51(2):114-6.
2012: Takahiro Mizukami; Toshiro Sato; Tomomitsu Doi; Tango Handa; Atsushi Hayashi; Tadakazu Hisamatsu; Li Jun; Takanori Kanai; Atsuhiro Matsumoto; Katsuyoshi Matsuoka; Yohei Mikami; Toshifumi Hibi
CCR9+ macrophages are required for eradication of peritoneal bacterial infections and prevention of polymicrobial sepsis.
Immunology letters 2012;147(1-2):75-9.
2012: Hiromasa Takaishi; Masao Takemura; Tomoharu Yajima; Shigeo Yoshizawa; Yasushi Iwao; Takanori Kanai; Atsushi Nakazawa; Akira Nikai; Shoichi Ozaki; Fumihiko Sugata; Shinsuke Funakoshi; Yasuo Hamamoto; Toshifumi Hibi
Anti-high mobility group box 1 and box 2 non-histone chromosomal proteins (HMGB1/HMGB2) antibodies and anti-Saccharomyces cerevisiae antibodies (ASCA): accuracy in differentially diagnosing UC and CD and correlation with inflammatory bowel disease phenotype.
Journal of gastroenterology 2012;47(9):969-77.
2012: Juntaro Matsuzaki; S Okada; Hidekazu Suzuki; S Fukuhara; Y Fukushima; K Hirata; Toshifumi Hibi
High frequency of overlap between functional dyspepsia and overactive bladder.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2012;24(9):821-7.
2012: Erika Kuwahara; Yuji Nishiwaki; Keiko Asakura; Toshifumi Hibi; Nagamu Inoue; Mamoru Watanabe; Toru Takebayashi
Effects of family history on inflammatory bowel disease characteristics in Japanese patients.
Journal of gastroenterology 2012;47(9):961-8.
2012: Shinta Mizuno; Nobuhiro Nakamoto; Yuichi Ono; Tomohisa Sujino; Hiromasa Takaishi; Tadakazu Hisamatsu; Takanori Kanai; Atsuhiro Matsumoto; Katsuyoshi Matsuoka; Yohei Mikami; Tango Handa; Atsushi Hayashi; Toshifumi Hibi
CCR9+ plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice.
Immunology letters 2012;146(1-2):64-9.
2012: Toshifumi Hibi; Ichiro Hirata; Hiroaki Ito; Kazuhiko Kawakami; Yoshitaka Kinouchi; Toshifumi Ashida; Takayuki Matsumoto; Takayuki Matsumoto; Kenta Motegi; Satoshi Motoya; Atsushi Sakuraba; Yasuo Suzuki; Masakazu Takazoe; Shinji Tanaka; Mamoru Watanabe; Toshiyuki Matsui
Retrieval of serum infliximab level by shortening the maintenance infusion interval is correlated with clinical efficacy in Crohn's disease.
Inflammatory bowel diseases 2012;18(8):1480-7.
2012: Yosuke Ida; Hiroyuki Imaeda; Takanori Kanai; Makoto Naganuma; Rieko Bessho; Toshifumi Hibi; Naoki Hosoe; Riko Ichikawa; Haruhiko Ogata
Effects of the oral administration of mosapride citrate on capsule endoscopy completion rate.
Gut and liver 2012;6(3):339-43.
2012: Naoteru Miyata; Keita Saeki; Akiko Yokoyama; Toshifumi Azuma; Hajime Higuchi; Shigenari Hozawa; Toru Igarashi; Ayano Kabashima; Toshifumi Hibi
Transforming growth factor β and Ras/MEK/ERK signaling regulate the expression level of a novel tumor suppressor Lefty.
Pancreas 2012;41(5):745-52.
2012: Atsushi Sakuraba; Toshiro Sato; Hiromasa Takaishi; Yasushi Iwao; Hidehiko Matsukawa; Haruhiko Ogata; Susumu Okamoto; Toshifumi Hibi
The use of infliximab in the prevention of postsurgical recurrence in polysurgery Crohn's disease patients: a pilot open-labeled prospective study.
International journal of colorectal disease 2012;27(7):947-52.
2012: Hiroyuki Imaeda; Yasushi Iwao; Takanori Kanai; Kazuhiro Kashiwagi; Hiromasa Nakamizo; Toshifumi Hibi; Naoki Hosoe; Yosuke Ida; Haruhiko Ogata
Novel technique of endoscopic submucosal dissection by using external forceps for early rectal cancer (with videos).
Gastrointestinal endoscopy 2012;75(6):1253-7.
2012: Atsushi Sakuraba; Toshiro Sato; Hiromasa Takaishi; Nagamu Inoue; Yasushi Iwao; Katsuyoshi Matsuoka; Yuichi Morohoshi; Haruhiko Ogata; Susumu Okamoto; Toshifumi Hibi
Intermittent granulocyte and monocyte apheresis versus mercaptopurine for maintaining remission of ulcerative colitis: a pilot study.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2012;16(3):213-8.
2012: Riko Ichikawa; Hiroshi Itoh; Nobuhiko Kamada; Takanori Kanai; Mina T Kitazume; Katsuyoshi Matsuoka; Tetsuro Takayama; Mitsuhiro Watanabe; Kazuaki Yoneno; Hajime Higuchi; Tadakazu Hisamatsu; Toshifumi Hibi
Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway.
Immunology 2012;136(2):153-62.
2012: Tadakazu Hisamatsu; Toshifumi Hibi
Is the dendritic cell a missing piece in the pathogenesis model of post-infectious irritable bowel syndrome?
Journal of gastroenterology and hepatology 2012;27(5):847-8.
2012: Hiroaki Yokomori; Kazunori Yoshimura; Masaya Oda; Toshifumi Hibi
Enhanced expressions of apelin on proliferative hepatic arterial capillaries in human cirrhotic liver.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(5):508-14.
2012: Haruhiko Ogata; Nobuyuki Hida; Fumihito Hirai; Jun Kato; Katsuyoshi Koyanagi; Toshiyuki Matsui; Takayuki Matsumoto; Toshifumi Hibi
Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis.
Inflammatory bowel diseases 2012;18(5):803-8.
2012: Ken Hatogai; Toshifumi Hibi; Naoki Hosoe; Yosuke Ida; Hiroyuki Imaeda; Yuka Ishibashi; Takanori Kanai; Kayoko Kimura; Sawako Okada; Jean-François Rey; Nobuhiro Tsukada; Shingo Usui; Kazuaki Yoneno; Haruhiko Ogata
Role of enhanced visibility in evaluating polyposis syndromes using a newly developed contrast image capsule endoscope.
Gut and liver 2012;6(2):218-22.
2012: Jun Miyoshi; Susumu Okamoto; Katsuyoshi Shimamura; Hiromasa Takaishi; Tomoharu Yajima; Shinsuke Funakoshi; Hajime Higuchi; Katsuyoshi Matsuoka; Toshifumi Hibi
5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis.
Anticancer research 2012;32(4):1193-202.
2012: Keita Saeki; Tomohisa Sujino; Hiromasa Takaishi; Kazuyoshi Takeda; Yoshiyuki Yamagishi; Akihiko Yoshimura; Shigenari Hozawa; Takanori Kanai; Naoteru Miyata; Yuji Nakamura; Masaru Nakano; Yuuichi Ono; Hirotoshi Ebinuma; Toshifumi Hibi
CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice.
Gastroenterology 2012;142(4):1010-1020.e9.
2012: Juntaro Matsuzaki; Hidekazu Suzuki; T Takebayashi; K Asakura; Y Fukushima; J M Inadomi; Toshifumi Hibi
Classification of functional dyspepsia based on concomitant bowel symptoms.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2012;24(4):325-e164.
2012: Eisuke Iwasaki; Kenji Kangawa; Tatsuhiro Masaoka; Toshihiro Nishizawa; Hidekazu Suzuki; Hiroshi Hosoda; Toshifumi Hibi
Enhanced gastric ghrelin production and secretion in rats with gastric outlet obstruction.
Digestive diseases and sciences 2012;57(4):858-64.
2012: Takanori Kanai; Katsuyoshi Matsuoka; Haruhiko Ogata; Tadakazu Hisamatsu; Yasushi Iwao; Toshifumi Hibi
[Mechanism and therapeutic strategy of second failure of infliximab treatment for Crohn's disease].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2012;109(3):364-9.
2012: Mamoru Watanabe; M Shamsul Alam; Anne Camez; Jingdong Chao; Toshifumi Hibi; Kathleen G Lomax; Susan K Paulson
Adalimumab for the induction and maintenance of clinical remission in Japanese patients with Crohn's disease.
Journal of Crohn's & colitis 2012;6(2):160-73.
2012: Katsuyoshi Matsuoka; Toshifumi Hibi
[Anti-viral therapy for ulcerative colitis complicated with cytomegalovirus colitis].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 1():387-9.
2012: Hidekazu Suzuki; Sawako Okada; Toshifumi Hibi
[Nervous and endocrine aspects of inflammatory bowel disease].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 1():106-11.
2012: Tadakazu Hisamatsu; Toshifumi Hibi
[Contribution of intestinal macrophage to gut immune homeostasis and its disruption in inflammatory bowel disease].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 1():85-90.
2012: Sachiko Mogami; Hidekazu Suzuki; Seiichiro Fukuhara; Kenji Kangawa; Juntaro Matsuzaki; Toshifumi Hibi
Reduced ghrelin production induced anorexia after rat gastric ischemia and reperfusion.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(3):G359-64.
2012: Nobuhiro Nakamoto; Keisuke Ojiro; Yuichi Ono; Hidetsugu Saito; Takanori Kanai; Martin Lipp; Paul E Love; Yohei Mikami; Po-Sung Chu; Hirotoshi Ebinuma; Toshifumi Hibi
CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.
Gastroenterology 2012;142(2):366-76.
2012: Naoki Hosoe; Riko Ichikawa; Yosuke Ida; Hiroyuki Imaeda; Takanori Kanai; Makoto Naganuma; Rieko Bessho; Toshifumi Hibi; Jean-François Rey; Haruhiko Ogata
Evaluations of capsule endoscopy software in reducing the reading time and the rate of false negatives by inexperienced endoscopists.
Clinics and research in hepatology and gastroenterology 2012;36(1):66-71.
2012: Yoshimasa Saito; Hidekazu Suzuki; Hitoshi Tsugawa; Kenro Hirata; Naoki Hosoe; Hiroyuki Imaeda; Juntaro Matsuzaki; Makio Mukai; Masahiko Nakamura; Hidetsugu Saito; Toshifumi Hibi
Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication.
PloS one 2012;7(11):e47396.
2012: Yuriko Maruyama; Katsuyoshi Matsuoka; Makoto Naganuma; Haruhiko Ogata; Tadakazu Hisamatsu; Nagamu Inoue; Yasushi Iwao; Takanori Kanai; Toshifumi Hibi
A case of intestinal Behçet's disease treated with infliximab monotherapy who successfully maintained clinical remission and complete mucosal healing for six years.
Internal medicine (Tokyo, Japan) 2012;51(16):2125-9.
2012: Aki Kawakami; Toshifumi Hibi; Yasushi Iwao; Makoto Naganuma; Ryota Ochiai; Makoto Tanaka; Keiko Kazuma
Difficulties in taking aminosalicylates for patients with ulcerative colitis.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 2012;35(1):24-31.
2012: Tadakazu Hisamatsu; Nagamu Inoue; Yasushi Iwao; Takanori Kanai; Mina T Kitazume; Katsuyoshi Matsuoka; Takahiko Muramatsu; Haruhiko Ogata; Susumu Okamoto; Nobukazu Ono; Ryosei Sakai; Manabu Suzuki; Michihide Uo; Tomoharu Yajima; Minoru Yamakado; Toshihiko Ando; Ayatoshi Andou; Masaki Hashimoto; Toshifumi Hibi
Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease.
PloS one 2012;7(1):e31131.
2012: Hidekazu Suzuki; Hitoshi Tsugawa; Sachiko Mogami; Toshihiro Nishizawa; Toshifumi Hibi
Roles of oxidative stress in stomach disorders.
Journal of clinical biochemistry and nutrition 2012;50(1):35-9.
2011: Kengo Tomita; Hirokazu Yokoyama; Hirotoshi Ebinuma; Ryota Hokari; Rie Irie; Soichiro Miura; Hidetsugu Saito; Takahiro Suzuki; Toshiaki Teratani; Toshifumi Hibi
Serum immunoglobulin a concentration is an independent predictor of liver fibrosis in nonalcoholic steatohepatitis before the cirrhotic stage.
Digestive diseases and sciences 2011;56(12):3648-54.
2011: Hiroaki Yokomori; Kazunori Yoshimura; Fumihiko Kaneko; Masaya Oda; Toshifumi Hibi
Aquaporin-1 associated with hepatic arterial capillary proliferation on hepatic sinusoid in human cirrhotic liver.
Liver international : official journal of the International Association for the Study of the Liver 2011;31(10):1554-64.
2011: Hiroshi Hirose; Shigenari Hozawa; Toshifumi Hibi; Tetsuro Takayama; Ikuo Saito
Prediction of metabolic syndrome using artificial neural network system based on clinical data including insulin resistance index and serum adiponectin.
Computers in biology and medicine 2011;41(11):1051-6.
2011: Toshihiro Nishizawa; Hidekazu Suzuki; Hitoshi Tsugawa; Kenro Hirata; Juntaro Matsuzaki; Hiroe Muraoka; Toshifumi Hibi
Helicobacter pylori resistance to rifabutin in the last 7 years.
Antimicrobial agents and chemotherapy 2011;55(11):5374-5.
2011: Hiroyuki Imaeda; Yasushi Iwao; Rieko Nakamura; Haruhiko Ogata; Yoshimasa Saito; Hidekazu Suzuki; Naoki Hosoe; Yosuke Ida; Toshifumi Hibi
Effect of lansoprazole versus roxatidine on prevention of bleeding and promotion of ulcer healing after endoscopic submucosal dissection for superficial gastric neoplasia.
Journal of gastroenterology 2011;46(11):1267-72.
2011: Hidekazu Suzuki; Toshifumi Hibi
Overlap syndrome of functional dyspepsia and irritable bowel syndrome - are both diseases mutually exclusive?
Journal of neurogastroenterology and motility 2011;17(4):360-5.
2011: Rieko Bessho; Naoki Hosoe; Nagamu Inoue; Takanori Kanai; Taku Kobayashi; Makio Mukai; Haruhiko Ogata; Tetsuro Takayama; Toshifumi Hibi
Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis.
Journal of gastroenterology 2011;46(10):1197-202.
2011: Hirotoshi Ebinuma; Po-sung Chu; Yuka Ishibashi; Takanori Kanai; Masahiro Kikuchi; Mina Komuta; Nobuhiro Nakamoto; Kiyoshi Ohkuma; Keisuke Ojiro; Hidetsugu Saito; Michiie Sakamoto; Tetsurou Takayama; Rumiko Umeda; Shingo Usui; Kanji Wakabayashi; Yoshiyuki Yamagishi; Toshifumi Hibi
Evaluation of liver fibrosis by transient elastography using acoustic radiation force impulse: comparison with Fibroscan(®).
Journal of gastroenterology 2011;46(10):1238-48.
2011: Kengo Tomita; Hirokazu Yokoyama; Hirotoshi Ebinuma; Ryota Hokari; Rie Irie; Soichiro Miura; Hidetsugu Saito; Takahiro Suzuki; Toshiaki Teratani; Toshifumi Hibi
Plasma free myristic acid proportion is a predictor of nonalcoholic steatohepatitis.
Digestive diseases and sciences 2011;56(10):3045-52.
2011: Hidekazu Suzuki; Juntaro Matsuzaki; Toshifumi Hibi
Metronidazole-based quadruple versus standard triple therapy: which is better as first-line therapy for Helicobacter pylori eradication?
Expert review of clinical pharmacology 2011;4(5):579-82.
2011: Naoki Hosoe; Yosuke Ida; Hiroyuki Imaeda; Takanori Kanai; Seiki Kobayashi; Rieko Bessho; Toshifumi Hibi; Susumu Okamoto; Riko Saito; Haruhiko Ogata
A case of beef tapeworm (Taenia saginata) infection observed by using video capsule endoscopy and radiography (with videos).
Gastrointestinal endoscopy 2011;74(3):690-1.
2011: Jun Miyoshi; Makio Mukai; Atsushi Nakazawa; Haruhiko Ogata; Susumu Okamoto; Katsuyoshi Shimamura; Tomoharu Yajima; Tadakazu Hisamatsu; Nagamu Inoue; Yasushi Iwao; Takanori Kanai; Katsuyoshi Matsuoka; Toshifumi Hibi
Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease.
Journal of gastroenterology 2011;46(9):1056-63.
2011: Tomohisa Sujino; Hiromasa Takaishi; Akihiko Yoshimura; Tomomitsu Doi; Atsushi Hayashi; Tadakazu Hisamatsu; Takanori Kanai; Dan R Littman; Katsuyoshi Matsuoka; Yohei Mikami; Haruhiko Ogata; Yuichi Ono; Toshifumi Hibi
Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells.
Gastroenterology 2011;141(3):1014-23.
2011: Makoto Naganuma; Minako Sako; Masakazu Takazoe; Toshifumi Hibi; Takaaki Kawaguchi; Hideaki Kimura; Reiko Kunisaki; Toshiyuki Matsui; Masakazu Nagahori; Hisae Yamamoto; Shojiro Yamamoto; Naoki Yoshimura; Mamoru Watanabe
Conception and pregnancy outcome in women with inflammatory bowel disease: A multicentre study from Japan.
Journal of Crohn's & colitis 2011;5(4):317-23.
2011: Motoko Izumiya; Shouko Nakamura; Tai Ohmori; Gen Sakai; Jin Sugiura; Hiromasa Takaishi; Yoshiyuki Yamagishi; Masayuki Adachi; Shinsuke Funakoshi; Hajime Higuchi; Eri Irie; Toshifumi Hibi
[A case of metastatic esophageal cancer - endoscopic resection of the primary site following systemic chemotherapies].
Gan to kagaku ryoho. Cancer & chemotherapy 2011;38(7):1167-70.
2011: Hidekazu Suzuki; Sawako Okada; Toshifumi Hibi
Proton-pump inhibitors for the treatment of functional dyspepsia.
Therapeutic advances in gastroenterology 2011;4(4):219-26.
2011: Maiko Takita; Kan Handa; Ken Hatogai; Toshifumi Hibi; Hajime Higuchi; Eisuke Iwasaki; Motoko Izumiya; Ryohei Kishino; Norio Maeda; Akira Mizuki; Kiyoshi Mukai; Atsushi Nakazawa; Eri Seki; Yutaka Shimoyama; Hiromasa Takaishi; Nobuhiro Tsukada
[Advanced gallbladder cancer that showed complete response to gemcitabine plus S-1 chemotherapy].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(7):1263-70.
2011: Hiroshi Ohara; Hiroshi Serizawa; Kanji Tsuchimoto; Satoshi Tsunematsu; Kanji Wakabayashi; Noriaki Watanabe; Yasuhisa Ishii; Yukako Kato; Naoki Kumagai; Masaru Nakano; Toshifumi Hibi
[A case of pneumatosis cystoides intestinalis induced by steroid pulse therapy for severe acute hepatitis B].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(7):1237-43.
2011: Yosuke Ida; Toshifumi Hibi
[Endoscopic findings and characteristics of NSAIDs-induced mucosal injuries in the upper/lower gastrointestinal tract].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(6):972-5.
2011: Toshihiro Nishizawa; Hidekazu Suzuki; Hitoshi Tsugawa; Hiroe Muraoka; Juntaro Matsuzaki; Kenro Hirata; Fumiaki Ikeda; Masahiko Takahashi; Toshifumi Hibi
Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication.
Antimicrobial agents and chemotherapy 2011;55(6):3012-4.
2011: Toshifumi Hibi; Keisuke Inaba; Hiroyuki Konno
[Q & A. Multiple arterial lesions discovered at the development of hemorrhage of the pancreatic head lesion].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(5):821, 825.
2011: Hidekazu Suzuki; Juntaro Matsuzaki; Toshifumi Hibi
What is the difference between Helicobacter pylori-associated dyspepsia and functional dyspepsia?
Journal of neurogastroenterology and motility 2011;17(2):124-30.
2011: Hidekazu Suzuki; Toshihiro Nishizawa; Toshifumi Hibi
Can Helicobacter pylori-associated dyspepsia be categorized as functional dyspepsia?
Journal of gastroenterology and hepatology 2011;26 Suppl 3():42-5.
2011: H Naruse; T Hisamatsu; Y Yamauchi; J E Chang; K Matsuoka; M T Kitazume; K Arai; S Ando; Takanori Kanai; N Kamada; Toshifumi Hibi
Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages.
Clinical and experimental immunology 2011;164(1):137-44.
2011: Tadakazu Hisamatsu; Toshifumi Hibi
[Long-term prognosis of Crohn's disease].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(3):373-80.
2011: Hidekazu Suzuki; Juntaro Matsuzaki; Toshifumi Hibi
Ghrelin and oxidative stress in gastrointestinal tract.
Journal of clinical biochemistry and nutrition 2011;48(2):122-5.
2011: Juntaro Matsuzaki; Hidekazu Suzuki; Keiko Asakura; Yoshimasa Saito; Kenro Hirata; Toru Takebayashi; Toshifumi Hibi
Etiological difference between ultrashort- and short-segment Barrett's esophagus.
Journal of gastroenterology 2011;46(3):332-8.
2011: Seiji Kawamata; Koichi Matsuzaki; Miki Murata; Toshihito Seki; Katsuyoshi Matsuoka; Yasushi Iwao; Toshifumi Hibi; Kazuichi Okazaki
Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis.
Inflammatory bowel diseases 2011;17(3):683-95.
2011: Makoto Naganuma; Mamoru Watanabe; Toshifumi Hibi
Safety and usefulness of balloon endoscopy in Crohn's disease patients with postoperative ileal lesions.
Journal of Crohn's & colitis 2011;5(1):73-4.
2011: Hiroaki Yokomori; Masaya Oda; Kazunori Yoshimura; Sanae Machida; Fumihiko Kaneko; Toshifumi Hibi
Overexpression of apelin receptor (APJ/AGTRL1) on hepatic stellate cells and sinusoidal angiogenesis in human cirrhotic liver.
Journal of gastroenterology 2011;46(2):222-31.
2011: Hitoshi Tsugawa; Hidekazu Suzuki; Hiroe Muraoka; Fumiaki Ikeda; Kenro Hirata; Juntaro Matsuzaki; Yoshimasa Saito; Toshifumi Hibi
Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pylori.
Biochemical and biophysical research communications 2011;404(2):656-60.
2011: Tadakazu Hisamatsu; Toshifumi Hibi
[Progress in management of Crohn's disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(1):85-95.
2011: Katsuyoshi Matsuoka; Toshifumi Hibi
[Viral infection of the small intestine].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(1):65-70.
2011: Yoshimasa Saito; Ayami Sato; Hidekazu Suzuki; Kana Yamada; Yusuke Kasai; Misa Matsuura; Hidetsugu Saito; Toshifumi Hibi
MicroRNAs in Hepatobiliary and Pancreatic Cancers.
Frontiers in genetics 2011;2():66.
2011: Tetsuro Takayama; Kanji Wakabayashi; Yoshiyuki Yamagishi; Hirotoshi Ebinuma; Toshifumi Hibi; Takanori Kanai; Keisuke Ojiro; Hidetsugu Saito; Shinichiro Tada
Prediction of effect of pegylated interferon alpha-2b plus ribavirin combination therapy in patients with chronic hepatitis C infection.
PloS one 2011;6(12):e27223.
2011: Hideaki Kanamori; Takao Kawakami; Yutaka Kyono; Yohei Masugi; Taisuke Mori; Keiko Nagasaka; Atsushi Ogiwara; Hidetsugu Saito; Wenlin Du; Hirotoshi Ebinuma; Kathryn Effendi; Toshifumi Hibi; Minoru Tanabe; Ken Yamazaki; Michiie Sakamoto
Identification by differential tissue proteome analysis of talin-1 as a novel molecular marker of progression of hepatocellular carcinoma.
Oncology 2011;80(5-6):406-15.
2011: R Ichikawa; Naoki Hosoe; Hiroyuki Imaeda; K Takabayashi; R Bessho; Y Ida; Makoto Naganuma; Tadakazu Hisamatsu; Nagamu Inoue; Takanori Kanai; Yasushi Iwao; Makio Mukai; Toshifumi Hibi; Haruhiko Ogata
Evaluation of small-intestinal abnormalities in adult patients with Henoch-Schönlein purpura using video capsule.
Endoscopy 2011;43 Suppl 2 UCTN():E162-3.
2011: Megumi Toyoda-Akui; Hiroaki Yokomori; Fumihiko Kaneko; Yuki Shimizu; Hajime Takeuchi; Kumiko Tahara; Tadashi Motoori; Makoto Ohbu; Masaya Oda; Toshifumi Hibi
A case of drug-induced hepatic injury associated with sitagliptin.
Internal medicine (Tokyo, Japan) 2011;50(9):1015-20.
2011: Yoshimasa Saito; Hidekazu Suzuki; Hitoshi Tsugawa; Sachiko Suzuki; Juntaro Matsuzaki; Kenro Hirata; Toshifumi Hibi
Dysfunctional gastric emptying with down-regulation of muscle-specific microRNAs in Helicobacter pylori-infected mice.
Gastroenterology 2011;140(1):189-98.
2011: Hitoshi Tsugawa; Hidekazu Suzuki; Kazue Satoh; Kenro Hirata; Juntaro Matsuzaki; Yoshimasa Saito; Makoto Suematsu; Toshifumi Hibi
Two amino acids mutation of ferric uptake regulator determines Helicobacter pylori resistance to metronidazole.
Antioxidants & redox signaling 2011;14(1):15-23.
2010: Hiroyuki Imaeda; Naoki Hosoe; Hiromasa Nakamizo; Kazuhiro Kashiwagi; Hidekazu Suzuki; Yoshimasa Saito; Kazuhiro Suganuma; Yosuke Ida; Juntaro Matsuzaki; Eisuke Iwasaki; Yasushi Iwao; Haruhiko Ogata; Toshifumi Hibi
Clinical results of observation of the upper gastrointestinal tract by transgastrostomic endoscopy using an ultrathin endoscope.
Journal of gastroenterology and hepatology 2010;25(12):1850-4.
2010: Juntaro Matsuzaki; Hidekazu Suzuki; Yuriko Minegishi; Etsuko Sugai; Hitoshi Tsugawa; Masato Yasui; Toshifumi Hibi
Acid suppression by proton pump inhibitors enhances aquaporin-4 and KCNQ1 expression in gastric fundic parietal cells in mouse.
Digestive diseases and sciences 2010;55(12):3339-48.
2010: Taku Kobayashi; Makoto Naganuma; Susumu Okamoto; Tadakazu Hisamatsu; Nagamu Inoue; Hitoshi Ichikawa; Tetsuro Takayama; Riko Saito; Tomohisa Sujino; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi
Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis.
Journal of gastroenterology 2010;45(11):1129-37.
2010: Yoshiyuki Yamagishi; Hajime Higuchi; Motoko Izumiya; Gen Sakai; Hideko Iizuka; Shoko Nakamura; Masayuki Adachi; Sigenari Hozawa; Hiromasa Takaishi; Toshifumi Hibi
Gemcitabine as first-line chemotherapy in elderly patients with unresectable pancreatic carcinoma.
Journal of gastroenterology 2010;45(11):1146-54.
2010: Takeshi Mizukami; Imaeda Hiroyuki; Toshifumi Hibi
Anchor clip technique helps in easy prevention of post-polypectomy hemorrhage of large colonic polyps.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2010;22(4):366-9.
2010: Tomonori Yaguchi; Hiroyuki Imaeda; Masahiro Kizaki; Naoki Hosoe; Hidekazu Suzuki; Haruhiko Ogata; Yasushi Iwao; Kaori Kameyama; Yasuo Ikeda; Toshifumi Hibi
Partial regression of duodenal lesions of intestinal follicular lymphoma after antibiotic treatment.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2010;22(4):316-8.
2010: Yukako Ono; Takehiko Mori; Jun Kato; Akiko Yamane; Tomoharu Yajima; Yasushi Iwao; Toshifumi Hibi; Shinichiro Okamoto
Hemorrhagic colonic ulcers caused by dasatinib for chronic myelogenous leukemia.
International journal of hematology 2010;92(3):556-8.
2010: Keisuke Ojiro; Hirotoshi Ebinuma; Nobuhiro Nakamoto; Kanji Wakabayashi; Yohei Mikami; Yuichi Ono; Chu Po-Sung; Shingo Usui; Rumiko Umeda; Hiromasa Takaishi; Yoshiyuki Yamagishi; Hidetsugu Saito; Takanori Kanai; Toshifumi Hibi
MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis.
Biochemical and biophysical research communications 2010;399(4):744-9.
2010: Yohei Mikami; Takanori Kanai; Tomohisa Sujino; Yuichi Ono; Atsushi Hayashi; Akira Okazawa; Nobuhiko Kamada; Katsuyoshi Matsuoka; Tadakazu Hisamatsu; Susumu Okamoto; Hiromasa Takaishi; Nagamu Inoue; Haruhiko Ogata; Toshifumi Hibi
Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.
European journal of immunology 2010;40(9):2409-22.
2010: Tetsuro Takayama; Nobuhiko Kamada; Hiroshi Chinen; Susumu Okamoto; Mina T Kitazume; Jonathan Chang; Yumi Matuzaki; Sadafumi Suzuki; Akira Sugita; Kazutaka Koganei; Tadakazu Hisamatsu; Takanori Kanai; Toshifumi Hibi
Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.
Gastroenterology 2010;139(3):882-92, 892.e1-3.
2010: Kaori Kameyama; Yasuhiro Nemoto; Takanori Kanai; Tamako Shinohara; Ryuichi Okamoto; Kiichiro Tsuchiya; Tetsuya Nakamura; Naoya Sakamoto; Teruji Totsuka; Toshifumi Hibi; Mamoru Watanabe
IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells in chronic colitis.
European journal of immunology 2010;40(9):2423-36.
2010: Naoki Hosoe; Taku Kobayashi; Takanori Kanai; Rieko Bessho; Tetsuro Takayama; Nagamu Inoue; Hiroyuki Imaeda; Yasushi Iwao; Seiki Kobayashi; Makio Mukai; Haruhiko Ogata; Toshifumi Hibi
In vivo visualization of trophozoites in patients with amoebic colitis by using a newly developed endocytoscope.
Gastrointestinal endoscopy 2010;72(3):643-6.
2010: Juntaro Matsuzaki; Hidekazu Suzuki; Eisuke Iwasaki; Hitoshi Yokoyama; Y Sugino; Toshifumi Hibi
Serum lipid levels are positively associated with non-erosive reflux disease, but not with functional heartburn.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2010;22(9):965-70, e251.
2010: Makoto Naganuma; Hitoshi Ichikawa; Nagamu Inoue; Taku Kobayashi; Susumu Okamoto; Tadakazu Hisamatsu; Takanori Kanai; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi
Novel endoscopic activity index is useful for choosing treatment in severe active ulcerative colitis patients.
Journal of gastroenterology 2010;45(9):936-43.
2010: Asaka Sato; Makoto Naganuma; Keiko Asakura; Yuji Nishiwaki; Tomoharu Yajima; Tadakazu Hisamatsu; Yasushi Iwao; Toru Takebayashi; Mamoru Watanabe; Toshifumi Hibi
Conception outcomes and opinions about pregnancy for men with inflammatory bowel disease.
Journal of Crohn's & colitis 2010;4(2):183-8.
2010: Hidekazu Suzuki; Toshifumi Hibi
Acotiamide (Z-338) as a possible candidate for the treatment of functional dyspepsia.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2010;22(6):595-9.
2010: Satoshi Kurita; Hajime Higuchi; Yoshimasa Saito; Nobuhiro Nakamoto; Hiromasa Takaishi; Shinichiro Tada; Hidetsugu Saito; Gregory J Gores; Toshifumi Hibi
DNMT1 and DNMT3b silencing sensitizes human hepatoma cells to TRAIL-mediated apoptosis via up-regulation of TRAIL-R2/DR5 and caspase-8.
Cancer science 2010;101(6):1431-9.
2010: Kenro Hirata; Hidekazu Suzuki; Toshihiro Nishizawa; Hitoshi Tsugawa; Hiroe Muraoka; Yoshimasa Saito; Juntaro Matsuzaki; Toshifumi Hibi
Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori.
Journal of gastroenterology and hepatology 2010;25 Suppl 1():S75-9.
2010: Juntaro Matsuzaki; Hidekazu Suzuki; Hitoshi Tsugawa; Toshihiro Nishizawa; Toshifumi Hibi
Homology model of the DNA gyrase enzyme of Helicobacter pylori, a target of quinolone-based eradication therapy.
Journal of gastroenterology and hepatology 2010;25 Suppl 1():S7-10.
2010: Masayuki Suzuki; Hidekazu Suzuki; Yuriko Minegishi; Kosei Ito; Toshihiro Nishizawa; Toshifumi Hibi
H. pylori-Eradication Therapy Increases RUNX3 Expression in the Glandular Epithelial Cells in Enlarged-Fold Gastritis.
Journal of clinical biochemistry and nutrition 2010;46(3):259-64.
2010: S Suzuki; Hidekazu Suzuki; K Horiguchi; Hitoshi Tsugawa; Juntaro Matsuzaki; T Takagi; Naoki Shimojima; Toshifumi Hibi
Delayed gastric emptying and disruption of the interstitial cells of Cajal network after gastric ischaemia and reperfusion.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2010;22(5):585-93, e126.
2010: Hiroyuki Imaeda; Naoki Hosoe; Kazuhiro Kashiwagi; Yosuke Ida; Yoshimasa Saito; Hidekazu Suzuki; Koichi Aiura; Haruhiko Ogata; Koichiro Kumai; Toshifumi Hibi
Autofluorescence videoendoscopy system using the SAFE-3000 for assessing superficial gastric neoplasia.
Journal of gastroenterology and hepatology 2010;25(4):706-11.
2010: Hidekazu Suzuki; Toshihiro Nishizawa; Toshifumi Hibi
Helicobacter pylori eradication therapy.
Future microbiology 2010;5(4):639-48.
2010: Nobuhiko Kamada; Tadakazu Hisamatsu; Haruki Honda; Taku Kobayashi; Hiroshi Chinen; Tetsuro Takayama; Mina T Kitazume; Susumu Okamoto; Kazutaka Koganei; Akira Sugita; Takanori Kanai; Toshifumi Hibi
TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease.
Inflammatory bowel diseases 2010;16(4):568-75.
2010: Yohsuke Makino; Hidekazu Suzuki; Toshihiro Nishizawa; Kaori Kameyama; Tadakazu Hisamatsu; Hiroyuki Imaeda; Makio Mukai; Toshifumi Hibi
Ileal Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma with a Large-Cell Component That Regressed Spontaneously.
Gut and liver 2010;4(1):117-21.
2010: Hiroaki Yokomori; Masaya Oda; Kazunori Yoshimura; Shu-ichi Watanabe; Toshifumi Hibi
Aberrant expressions of aquaporin-1 in association with capillarized sinusoidal endothelial cells in cirrhotic rat liver.
Medical molecular morphology 2010;43(1):6-12.
2010: Yasuhiro Takada; Tadakazu Hisamatsu; Nobuhiko Kamada; Mina T Kitazume; Haruki Honda; Yosuke Oshima; Riko Saito; Tetsuro Takayama; Taku Kobayashi; Hiroshi Chinen; Yohei Mikami; Takanori Kanai; Susumu Okamoto; Toshifumi Hibi
Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2671-6.
2010: Juntaro Matsuzaki; Hidekazu Suzuki; Keiko Asakura; Yoshimasa Saito; Kenro Hirata; Toru Takebayashi; Toshifumi Hibi
Gallstones increase the prevalence of Barrett's esophagus.
Journal of gastroenterology 2010;45(2):171-8.
2010: Hirokazu Yokoyama; Haruko Shiraishi-Yokoyama; Toshifumi Hibi
Structural features of the NAD-dependent in situ retinoic acid supply system in esophageal mucosa.
Alcoholism, clinical and experimental research 2010;34 Suppl 1():S39-44.
2010: Mitsuyasu Nakamura; Hidetsugu Saito; Masanori Ikeda; Ryota Hokari; Nobuyuki Kato; Toshifumi Hibi; Soichiro Miura
An antioxidant resveratrol significantly enhanced replication of hepatitis C virus.
World journal of gastroenterology : WJG 2010;16(2):184-92.
2010: Hidetsugu Saito; Hirotoshi Ebinuma; Keisuke Ojiro; Kanji Wakabayashi; Mika Inoue; Shinichiro Tada; Toshifumi Hibi
On-treatment predictions of success in peg-interferon/ribavirin treatment using a novel formula.
World journal of gastroenterology : WJG 2010;16(1):89-97.
2010: Rie Yamazaki; Takehiko Mori; Tomonori Nakazato; Yoshinobu Aisa; Hiroyuki Imaeda; Tadakazu Hisamatsu; Toshifumi Hibi; Shinichiro Okamoto
Non-tuberculous mycobacterial infection localized in small intestine developing after allogeneic bone marrow transplantation.
Internal medicine (Tokyo, Japan) 2010;49(12):1191-3.
2009: Yoshinori Horie; Masahiro Kikuchi; Yoshiyuki Yamagishi; Rumiko Umeda; Hirotoshi Ebinuma; Hidetsugu Saito; Shinzo Kato; Hiromasa Ishii; Toshifumi Hibi; Jing-Yan Han
Effect of a herbal medicine on fatty liver in rats fed ethanol chronically.
Nihon Arukōru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 2009;44(6):636-48.
2009: Takanori Kanai; Mamoru Watanabe; Toshifumi Hibi
Systemically circulating colitogenic memory CD4+T cells may be an ideal target for the treatment of inflammatory bowel diseases.
The Keio journal of medicine 2009;58(4):203-9.
2009: Hidekazu Suzuki; Juntaro Matsuzaki; Toshifumi Hibi
[Lifestyle-related diseases and H. pylori].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(12):2366-71.
2009: Atsushi Sakuraba; Satoshi Motoya; Kenji Watanabe; Masakazu Nishishita; Kazunari Kanke; Toshiyuki Matsui; Yasuo Suzuki; Tadayuki Oshima; Reiko Kunisaki; Takayuki Matsumoto; Hiroyuki Hanai; Ken Fukunaga; Naoki Yoshimura; Toshimi Chiba; Shinsuke Funakoshi; Nobuo Aoyama; Akira Andoh; Hiroshi Nakase; Yohei Mizuta; Ryoichi Suzuki; Taiji Akamatsu; Masahiro Iizuka; Toshifumi Ashida; Toshifumi Hibi
An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis as compared with routine weekly treatment.
The American journal of gastroenterology 2009;104(12):2990-5.
2009: Tadakazu Hisamatsu; Toshifumi Hibi
Pathogen-specific antibody: cause or effect?
Gastroenterology 2009;137(5):1570-3.
2009: Atsushi Sakuraba; Toshiro Sato; Nobuhiko Kamada; Mina Kitazume; Akira Sugita; Toshifumi Hibi
Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.
Gastroenterology 2009;137(5):1736-45.
2009: Hidekazu Suzuki; Masayuki Suzuki; Hiroyuki Imaeda; Toshifumi Hibi
Helicobacter pylori and microcirculation.
Microcirculation (New York, N.Y. : 1994) 2009;16(7):547-58.
2009: Takayuki Tomita; Takanori Kanai; Teruji Totsuka; Yasuhiro Nemoto; Ryuichi Okamoto; Kiichiro Tsuchiya; Naoya Sakamoto; Toshiaki Ohteki; Toshifumi Hibi; Mamoru Watanabe
IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4(+) memory T cells in chronic colitis.
European journal of immunology 2009;39(10):2737-47.
2009: Yasuyo Wada; Tadakazu Hisamatsu; Nobuhiko Kamada; Susumu Okamoto; Toshifumi Hibi
Retinoic acid contributes to the induction of IL-12-hypoproducing dendritic cells.
Inflammatory bowel diseases 2009;15(10):1548-56.
2009: Nobuhiko Kamada; Tadakazu Hisamatsu; Haruki Honda; Taku Kobayashi; Hiroshi Chinen; Mina Tokutake Kitazume; Tetsuro Takayama; Susumu Okamoto; Kazutaka Koganei; Akira Sugita; Takanori Kanai; Toshifumi Hibi
Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):1724-31.
2009: Y Saito; Hidekazu Suzuki; Hitoshi Tsugawa; I Nakagawa; Juntaro Matsuzaki; Y Kanai; Toshifumi Hibi
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.
Oncogene 2009;28(30):2738-44.
2009: Makoto Naganuma; Toshifumi Hibi
[Current treatment for severe ulcerative colitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2009;106(7):978-88.
2009: Hidekazu Suzuki; J M Inadomi; Toshifumi Hibi
Japanese herbal medicine in functional gastrointestinal disorders.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2009;21(7):688-96.
2009: Takanori Kanai; Yasuhiro Nemoto; Nobuhiko Kamada; Teruji Totsuka; Tadakazu Hisamatsu; Mamoru Watanabe; Toshifumi Hibi
Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease.
Current opinion in gastroenterology 2009;25(4):306-13.
2009: Ayano Kabashima; Hajime Higuchi; Hiromasa Takaishi; Yumi Matsuzaki; Sadafumi Suzuki; Motoko Izumiya; Hideko Iizuka; Gen Sakai; Shigenari Hozawa; Toshifumi Azuma; Toshifumi Hibi
Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion.
International journal of cancer. Journal international du cancer 2009;124(12):2771-9.
2009: Hidekazu Suzuki; Yoshimasa Saito; Toshifumi Hibi
Helicobacter pylori and Gastric Mucosa-associated Lymphoid Tissue (MALT) Lymphoma: Updated Review of Clinical Outcomes and the Molecular Pathogenesis.
Gut and liver 2009;3(2):81-7.
2009: Tadakazu Hisamatsu; Toshifumi Hibi
[Biologics in current therapy for inflammatory bowel disease].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2009;32(3):168-79.
2009: Takanori Kanai; Yasuhiro Nemoto; Takayuki Tomita; Teruji Totsuka; Mamoru Watanabe; Toshifumi Hibi
Persistent retention of colitogenic CD4+ memory T cells causes inflammatory bowel diseases to become intractable.
Inflammatory bowel diseases 2009;15(6):926-34.
2009: Takeshi Nishimura; Toshifumi Azuma; Akiko Yokoyama; Hiromi Ochiai; Hidetsugu Saito; Toshifumi Hibi
New mechanism of transforming growth factor-beta signaling in hepatoma: Dramatic up-regulation of tumor initiating cells and epidermal growth factor receptor expression.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(5):501-9.
2009: Hiroyuki Imaeda; Naoki Hosoe; Yosuke Ida; Kazuhiro Kashiwagi; Yuichi Morohoshi; Kazuhiro Suganuma; Shuichi Nagakubo; Koichi Komatsu; Hidekazu Suzuki; Yoshimasa Saito; Koichi Aiura; Haruhiko Ogata; Yasushi Iwao; Koichiro Kumai; Yuko Kitagawa; Toshifumi Hibi
Novel technique of endoscopic submucosal dissection using an external grasping forceps for superficial gastric neoplasia.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2009;21(2):122-7.
2009: Naoki Hosoe; Hiroyuki Imaeda; Kazuhiro Kashiwagi; Makoto Naganuma; Nagamu Inoue; Hidekazu Suzuki; Kazuhiro Suganuma; Yosuke Ida; Hiromasa Nakamizo; Koichi Aiura; Haruhiko Ogata; Yasushi Iwao; Koichiro Kumai; Toshifumi Hibi
Clinical results of endoscopic hemostasis using a short transparent hood and short hemoclips for non-variceal upper gastrointestinal bleeding.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2009;21(2):93-6.
2009: Yuko Iwakami; Atsushi Sakuraba; Toshiro Sato; Yasuhiro Takada; Motoko Izumiya; Hitoshi Ichikawa; Toshifumi Hibi
Granulocyte and monocyte adsorption apheresis therapy modulates monocyte-derived dendritic cell function in patients with ulcerative colitis.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2009;13(2):138-46.
2009: Toshihiro Nishizawa; Hidekazu Suzuki; Toshifumi Hibi
Quinolone-Based Third-Line Therapy for Helicobacter pylori Eradication.
Journal of clinical biochemistry and nutrition 2009;44(2):119-24.
2009: Masashi Tsuruta; Hirotoshi Hasegawa; Yoshiyuki Ishii; Takashi Endo; Hiroki Ochiai; Toshifumi Hibi; Yuko Kitagawa
Hand-assisted versus conventional laparoscopic restorative proctocolectomy for ulcerative colitis.
Surgical laparoscopy, endoscopy & percutaneous techniques 2009;19(1):52-6.
2009: Hiroaki Yokomori; Masaya Oda; Kazunori Yoshimura; Toshihiro Nagai; Kayo Fujimaki; Shuichi Watanabe; Toshifumi Hibi
Caveolin-1 and Rac regulate endothelial capillary-like tubular formation and fenestral contraction in sinusoidal endothelial cells.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(2):266-76.
2009: Shinichiro Tada; Hidetsugu Saito; Hirotoshi Ebinuma; Keisuke Ojiro; Yoshiyuki Yamagishi; Naoki Kumagai; Yasutaka Inagaki; Tetsuya Masuda; Jiro Nishida; Masahiko Takahashi; Hiroshi Nagata; Toshifumi Hibi
Treatment of hepatitis C virus with peg-interferon and ribavirin combination therapy significantly affects lipid metabolism.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(2):195-9.
2009: Ayatoshi Andou; Tadakazu Hisamatsu; Susumu Okamoto; Hiroshi Chinen; Nobuhiko Kamada; Taku Kobayashi; Masaki Hashimoto; Tomohisa Okutsu; Kazutaka Shimbo; Tomoko Takeda; Hideki Matsumoto; Atsushi Sato; Hiroshi Ohtsu; Manabu Suzuki; Toshifumi Hibi
Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages.
Gastroenterology 2009;136(2):564-74.e2.
2009: Makoto Tanaka; Yasushi Iwao; Susumu Okamoto; Haruhiko Ogata; Toshifumi Hibi; Keiko Kazuma
Coping strategy when patients with quiescent Crohn's disease recognize that their conditions are worsening.
Journal of gastroenterology 2009;44(11):1109-12.
2009: Hidekazu Suzuki; Eisuke Iwasaki; Toshifumi Hibi
Helicobacter pylori and gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2009;12(2):79-87.
2009: Yoshiyuki Yamagishi; Hidetsugu Saito; Hirotoshi Ebinuma; Masahiro Kikuchi; Keisuke Ojiro; Hideaki Kanamori; Shinichiro Tada; Yoshinori Horie; Shinzo Kato; Toshifumi Hibi
A new prognostic formula for adult acute liver failure using computer tomography-derived hepatic volumetric analysis.
Journal of gastroenterology 2009;44(6):615-23.
2009: Toshihiro Nishizawa; Hidekazu Suzuki; Izumi Nakagawa; Yuriko Minegishi; Tatsuhiro Masaoka; Eisuke Iwasaki; Toshifumi Hibi
Early Helicobacter pylori eradication restores sonic hedgehog expression in the gastric mucosa of Mongolian gerbils.
Digestion 2009;79(2):99-108.
2009: Yoshimasa Saito; Hidekazu Suzuki; Toshifumi Hibi
The role of microRNAs in gastrointestinal cancers.
Journal of gastroenterology 2009;44 Suppl 19():18-22.
2009: Shoji Suzuki; Hidekazu Suzuki; Toshihiro Nishizawa; Fumihiko Kaneko; Sumire Ootani; Hiroe Muraoka; Yoshimasa Saito; Intetsu Kobayashi; Toshifumi Hibi
Past rifampicin dosing determines rifabutin resistance of Helicobacter pylori.
Digestion 2009;79(1):1-4.
2009: Masahiro Kikuchi; Kengo Tomita; Tadaki Nakahara; Naoto Kitamura; Toshiaki Teratani; Rie Irie; Hirokazu Yokoyama; Takahiro Suzuki; Terufumi Yokoyama; Takashi Taguchi; Shinobu Tanaka; Masaaki Noguchi; Tamiko Ohkura; Toshifumi Hibi
Utility of quantitative 99mTc-phytate scintigraphy to diagnose early-stage non-alcoholic steatohepatitis.
Scandinavian journal of gastroenterology 2009;44(2):229-36.
2008: Takako Komiyama; Tomoharu Yajima; Rie Kubota; Yasushi Iwao; Atsushi Sakuraba; Shinsuke Funakoshi; Kenichi Negishi; Ikuko Minami; Yoichi Tanaka; Hiroshi Mae; Toshifumi Hibi
Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients.
Journal of Crohn's & colitis 2008;2(4):315-21.
2008: Eisuke Iwasaki; Hidekazu Suzuki; Yoshinori Sugino; Tsutomu Iida; Toshihiro Nishizawa; Tatsuhiro Masaoka; Hiroshi Hosoda; Kenji Kangawa; Toshifumi Hibi
Decreased levels of adiponectin in obese patients with gastroesophageal reflux evaluated by videoesophagography: possible relationship between gastroesophageal reflux and metabolic syndrome.
Journal of gastroenterology and hepatology 2008;23 Suppl 2():S216-21.
2008: Toshihiro Nishizawa; Hidekazu Suzuki; Izumi Nakagawa; Eisuke Iwasaki; Tatsuhiro Masaoka; Toshifumi Hibi
Gatifloxacin-based triple therapy as a third-line regimen for Helicobacter pylori eradication.
Journal of gastroenterology and hepatology 2008;23 Suppl 2():S167-70.
2008: Shigenari Hozawa; Tetsuya Nakamura; Masaru Nakano; Masayuki Adachi; Hirotoshi Tanaka; Yoko Takahashi; Mine Tetsuya; Naoteru Miyata; Hiromitsu Soma; Toshifumi Hibi
Induction of matrix metalloproteinase-1 gene transcription by tumour necrosis factor alpha via the p50/p50 homodimer of nuclear factor-kappa B in activated human hepatic stellate cells.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(10):1418-25.
2008: Kengo Tomita; Akihiro Tanimoto; Rie Irie; Masahiro Kikuchi; Hirokazu Yokoyama; Toshiaki Teratani; Takahiro Suzuki; Takashi Taguchi; Masaaki Noguchi; Tamiko Ohkura; Toshifumi Hibi
Evaluating the severity of nonalcoholic steatohepatitis with superparamagnetic iron oxide-enhanced magnetic resonance imaging.
Journal of magnetic resonance imaging : JMRI 2008;28(6):1444-50.
2008: Taku Kobayashi; Susumu Okamoto; Tadakazu Hisamatsu; Nobuhiko Kamada; Hiroshi Chinen; R Saito; M T Kitazume; A Nakazawa; A Sugita; K Koganei; K Isobe; Toshifumi Hibi
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease.
Gut 2008;57(12):1682-9.
2008: Hitoshi Tsugawa; Hidekazu Suzuki; Izumi Nakagawa; Toshihiro Nishizawa; Yoshimasa Saito; Makoto Suematsu; Toshifumi Hibi
Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori.
Biochemical and biophysical research communications 2008;376(1):46-51.
2008: Hitoshi Ichikawa; Susumu Okamoto; Nobuhiko Kamada; Hisashi Nagamoto; Mina T Kitazume; Taku Kobayashi; Hiroshi Chinen; Tadakazu Hisamatsu; Toshifumi Hibi
Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice.
Inflammatory bowel diseases 2008;14(11):1483-90.
2008: Fumihiko Kaneko; Hiroaki Yokomori; Aya Sato; Hajime Takeuchi; Kumiko Tahara; Yasunobu Sekiguchi; Shigehisa Mori; Tadashi Motoori; Hirobumi Kondo; Toshifumi Hibi
A case of primary hepatic non-Hodgkin's lymphoma with chronic hepatitis C.
Medical molecular morphology 2008;41(3):171-4.
2008: Makoto Naganuma; Atsushi Sakuraba; Tadakazu Hisamatsu; Hiroki Ochiai; Hirotoshi Hasegawa; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi
Efficacy of infliximab for induction and maintenance of remission in intestinal Behçet's disease.
Inflammatory bowel diseases 2008;14(9):1259-64.
2008: Kengo Tomita; Yuichi Oike; Toshiaki Teratani; Takashi Taguchi; Masaaki Noguchi; Takahiro Suzuki; Akiko Mizutani; Hirokazu Yokoyama; Rie Irie; Hidetoshi Sumimoto; Atsushi Takayanagi; Kiichi Miyashita; Masaki Akao; Mitsuhisa Tabata; Gen Tamiya; Tamiko Ohkura; Toshifumi Hibi
Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice.
Hepatology (Baltimore, Md.) 2008;48(2):458-73.
2008: Tadakazu Hisamatsu; Haruhiko Ogata; Toshifumi Hibi
Innate immunity in inflammatory bowel disease: state of the art.
Current opinion in gastroenterology 2008;24(4):448-54.
2008: Shigeo Yoshizawa; Toshifumi Hibi
[New therapy in inflammatory bowel disease (infliximab)].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(7):1279-85.
2008: Hiromasa Takaishi; Takahiro Matsuki; Atsushi Nakazawa; Toshihiko Takada; Shoichi Kado; Takashi Asahara; Nobuhiko Kamada; Atsushi Sakuraba; Tomoharu Yajima; Hajime Higuchi; Nagamu Inoue; Haruhiko Ogata; Yasushi Iwao; Koji Nomoto; Ryuichiro Tanaka; Toshifumi Hibi
Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease.
International journal of medical microbiology : IJMM 2008;298(5-6):463-72.
2008: Mitsuyasu Nakamura; Hidetsugu Saito; Toshifumi Hibi
Advances in genomic research on hepatitis C virus with a useful tool, replicon system.
The Keio journal of medicine 2008;57(2):75-83.
2008: Nobuhiko Kamada; Tadakazu Hisamatsu; Susumu Okamoto; Hiroshi Chinen; Taku Kobayashi; Toshiro Sato; Atsushi Sakuraba; Mina T Kitazume; Akira Sugita; Kazutaka Koganei; Kiyoko S Akagawa; Toshifumi Hibi
Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis.
The Journal of clinical investigation 2008;118(6):2269-80.
2008: Takehiko Mori; Yoshinobu Aisa; Reiko Watanabe; Rie Yamazaki; Jun Kato; Takayuki Shimizu; Naoyuki Shigematsu; Atsushi Kubo; Tomonaru Yajima; Toshifumi Hibi; Yasuo Ikeda; Shinichiro Okamoto
Long-term follow-up of allogeneic hematopoietic stem cell transplantation for de novo acute myelogenous leukemia with a conditioning regimen of total body irradiation and granulocyte colony-stimulating factor-combined high-dose cytarabine.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(6):651-7.
2008: Tatsuhiro Masaoka; Hidekazu Suzuki; Toshifumi Hibi
Gastric epithelial cell modality and proton pump inhibitor.
Journal of clinical biochemistry and nutrition 2008;42(3):191-6.
2008: Mitsuyasu Nakamura; Hidetsugu Saito; Masanori Ikeda; Shinichiro Tada; Naoki Kumagai; Nobuyuki Kato; Kunitada Shimotohno; Toshifumi Hibi
Possible molecular mechanism of the relationship between NS5B polymorphisms and early clearance of hepatitis C virus during interferon plus ribavirin treatment.
Journal of medical virology 2008;80(4):632-9.
2008: Masayuki Suzuki; Hidekazu Suzuki; Toshifumi Hibi
Proton pump inhibitors and gastritis.
Journal of clinical biochemistry and nutrition 2008;42(2):71-5.
2008: Takehiko Mori; Yoshinobu Aisa; Tomoharu Yajima; Takayuki Shimizu; Jun Kato; Tomonori Nakazato; Toshifumi Hibi; Yasuo Ikeda; Shinichiro Okamoto
Esophageal varices and portal hypertensive gastropathy associated with hepatic veno-occlusive disease after allogeneic hematopoietic stem cell transplantation.
International journal of hematology 2008;87(2):231-2.
2008: Masanobu Nanno; Yasuyoshi Kanari; Tomoaki Naito; Nagamu Inoue; Tadakazu Hisamatsu; Hiroshi Chinen; Ken Sugimoto; Yasuyo Shimomura; Hideo Yamagishi; Tetsuo Shiohara; Satoshi Ueha; Kouji Matsushima; Makoto Suematsu; Atsushi Mizoguchi; Toshifumi Hibi; Atul K Bhan; Hiromichi Ishikawa
Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.
Gastroenterology 2008;134(2):481-90.
2008: Keisuke Ojiro; Makoto Naganuma; Hirotoshi Ebinuma; Hiroyoshi Kunimoto; Shinichiro Tada; Haruhiko Ogata; Yasushi Iwao; Hidetsugu Saito; Toshifumi Hibi
Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab.
Journal of gastroenterology 2008;43(5):397-401.
2008: Masayuki Suzuki; Shin Tanaka; Koichi Suzuki; Tetsuji Kitahora; Tatsuhiro Masaoka; Hidekazu Suzuki; Toshifumi Hibi
Persistent oxidative stress in the corpus mucosa is evoked by long-term treatment of H. pylori-infected patients with proton pump inhibitors.
Hepato-gastroenterology 2008;55(81):138-41.
2008: Keita Saeki; Shigenari Hozawa; Naoteru Miyata; Toshihiro Nishizawa; Hiromitsu Soma; Yasushi Iwao; Kaori Kameyama; Toshifumi Hibi
IgG4-negative autoimmune pancreatitis with sclerosing cholangitis and colitis: possible association with primary sclerosing cholangitis?
Internal medicine (Tokyo, Japan) 2008;47(10):943-8.
2008: Haruhiko Ogata; Koichiro Kumai; Hiroyuki Imaeda; Koichi Aiura; Tadakazu Hisamatsu; Susumu Okamoto; Yasushi Iwao; Yoshinori Sugino; Masaki Kitajima; Toshifumi Hibi
Clinical impact of a newly developed capsule endoscope: usefulness of a real-time image viewer for gastric transit abnormality.
Journal of gastroenterology 2008;43(3):186-92.
2008: Atsushi Sakuraba; Toshiro Sato; Makoto Naganuma; Yuichi Morohoshi; Katsuyoshi Matsuoka; Nagamu Inoue; Hiromasa Takaishi; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi
A pilot open-labeled prospective randomized study between weekly and intensive treatment of granulocyte and monocyte adsorption apheresis for active ulcerative colitis.
Journal of gastroenterology 2008;43(1):51-6.
2008: Nobuhiko Kamada; Kenichi Maeda; Nagamu Inoue; Tadakazu Hisamatsu; Susumu Okamoto; Kyong Su Hong; Takaya Yamada; Noriaki Watanabe; Kanji Tsuchimoto; Haruhiko Ogata; Toshifumi Hibi
Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells.
Infection and immunity 2008;76(1):214-20.
2007: T Nishizawa; Hidekazu Suzuki; Tatsuhiro Masaoka; Toshifumi Hibi
Education and imaging. Gastrointestinal: enhanced gastric mucosal blood flow in aspirin intoxication.
Journal of gastroenterology and hepatology 2007;22(11):2037.
2007: Kumi Kitamura; Shinichiro Tada; Nobuhiro Nakamoto; Kyoko Toda; Hitomi Horikawa; Satoshi Kurita; Satoshi Tsunematsu; Naoki Kumagai; Hiromasa Ishii; Hidetsugu Saito; Toshifumi Hibi
Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis.
Journal of gastroenterology and hepatology 2007;22(11):2022-33.
2007: Yoichi Fujiyama; Ryota Hokari; Soichiro Miura; Chikako Watanabe; Shunsuke Komoto; Tokushige Oyama; Chie Kurihara; Hiroshi Nagata; Toshifumi Hibi
Butter feeding enhances TNF-alpha production from macrophages and lymphocyte adherence in murine small intestinal microvessels.
Journal of gastroenterology and hepatology 2007;22(11):1838-45.
2007: Hiroyuki Imaeda; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi; Koichiro Kumai
[Expectation of video capsule endoscopy for diagnosis of NSAID induced enteropathy].
Nihon rinsho. Japanese journal of clinical medicine 2007;65(10):1896-901.
2007: Yuriko Minegishi; Hidekazu Suzuki; M Arakawa; Y Fukushima; Tatsuhiro Masaoka; T Ishikawa; N A Wright; Toshifumi Hibi
Reduced Shh expression in TFF2-overexpressing lesions of the gastric fundus under hypochlorhydric conditions.
The Journal of pathology 2007;213(2):161-9.
2007: Tokushige Oyama; Soichiro Miura; Chikako Watanabe; Ryota Hokari; Yoichi Fujiyama; Shunsuke Komoto; Yoshikazu Tsuzuki; Naoki Hosoe; Hiroshi Nagata; Toshifumi Hibi
CXCL12 and CCL20 play a significant role in mucosal T-lymphocyte adherence to intestinal microvessels in mice.
Microcirculation (New York, N.Y. : 1994) 2007;14(7):753-66.
2007: Mamoru Arakawa; Hidekazu Suzuki; Yuriko Minegishi; Yasushi Fukushima; Tatsuhiro Masaoka; Takashi Ishikawa; Hiroshi Hosoda; Kenji Kangawa; Toshifumi Hibi
Enhanced ghrelin expression and subsequent acid secretion in mice with genetic H(2)-receptor knockout.
Journal of gastroenterology 2007;42(9):711-8.
2007: Tatsuhiro Masaoka; Hidekazu Suzuki; Shingo Hori; Naoki Aikawa; Toshifumi Hibi
Blatchford scoring system is a useful scoring system for detecting patients with upper gastrointestinal bleeding who do not need endoscopic intervention.
Journal of gastroenterology and hepatology 2007;22(9):1404-8.
2007: Toshihiro Nishizawa; Hidekazu Suzuki; Tatsuhiro Masaoka; Eisuke Iwasaki; Toshifumi Hibi
Reduced conscious blood flow in the stomach during non-steroidal anti-inflammatory drugs administration assessed by flash echo imaging.
Scandinavian journal of gastroenterology 2007;42(9):1040-4.
2007: Takehiko Mori; Yoshinobu Aisa; Takayuki Shimizu; Rie Yamazaki; Ai Mihara; Tomoharu Yajima; Toshifumi Hibi; Yasuo Ikeda; Shinichiro Okamoto
Hepatic veno-occlusive disease after tranexamic acid administration in patients undergoing allogeneic hematopoietic stem cell transplantation.
American journal of hematology 2007;82(9):838-9.
2007: Hiroshi Chinen; Katsuyoshi Matsuoka; Toshiro Sato; Nobuhiko Kamada; Susumu Okamoto; Tadakazu Hisamatsu; Taku Kobayashi; Hirotoshi Hasegawa; Akira Sugita; Fukunori Kinjo; Jiro Fujita; Toshifumi Hibi
Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells.
Gastroenterology 2007;133(2):559-73.
2007: Haruhiko Ogata; Toshifumi Hibi
[Inflammatory bowel disease: current progress and future aspect].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2007;104(8):1155-64.
2007: Naoki Kumagai; Fumihiko Kaneko; Satoshi Tsunematsu; Kanji Tsuchimoto; Shinichiro Tada; H Saito; Toshifumi Hibi
Complexity of the HVR-1 quasispecies and disease activity in patients with hepatitis C.
European journal of clinical investigation 2007;37(7):566-72.
2007: Michiko Miyagi; Hirokazu Yokoyama; Toshifumi Hibi
Sugar microanalysis by HPLC with benzoylation: improvement via introduction of a C-8 cartridge and a high efficiency ODS column.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;854(1-2):286-90.
2007: Shigeo Yoshizawa; Katsuyoshi Matsuoka; Nagamu Inoue; Hiromasa Takaishi; Haruhiko Ogata; Yasushi Iwao; Makio Mukai; Tomonobu Fujita; Yutaka Kawakami; Toshifumi Hibi
Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.
Inflammatory bowel diseases 2007;13(7):865-73.
2007: Taku Kobayashi; Susumu Okamoto; Yuko Iwakami; Atsushi Nakazawa; Tadakazu Hisamatsu; Hiroshi Chinen; Nobuhiko Kamada; Toshio Imai; Hidemi Goto; Toshifumi Hibi
Exclusive increase of CX3CR1+CD28-CD4+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes.
Inflammatory bowel diseases 2007;13(7):837-46.
2007: Masahiko Takahashi; Hidetsugu Saito; Makiko Higashimoto; Toshifumi Hibi
Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: A pilot study.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(6):405-9.
2007: Makoto Tanaka; Yasushi Iwao; Satoshi Sasaki; Susumu Okamoto; Haruhiko Ogata; Toshifumi Hibi; Keiko Kazuma
Moderate dietary temperance effectively prevents relapse of Crohn disease: a prospective study of patients in remission.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 2007;30(3):202-10.
2007: Hidekazu Suzuki; Eisuke Iwasaki; Toshifumi Hibi
[Endoscopic therapy for gastroesophageal reflux disease].
Nihon rinsho. Japanese journal of clinical medicine 2007;65(5):895-9.
2007: Toshihiro Nishizawa; Hidekazu Suzuki; Tatsuhiro Masaoka; Yuriko Minegishi; Eisuke Iwasahi; Toshifumi Hibi
Helicobacter pylori eradication restored sonic hedgehog expression in the stomach.
Hepato-gastroenterology 2007;54(75):697-700.
2007: Masahiko Nakamura; Somay Yamagata Murayama; Hiroshi Serizawa; Yukie Sekiya; Masahiro Eguchi; Shinichi Takahashi; Kaori Nishikawa; Tetsufumi Takahashi; Tsukasa Matsumoto; Haruki Yamada; Toshifumi Hibi; Kanji Tsuchimoto; Hidenori Matsui
"Candidatus Helicobacter heilmannii" from a cynomolgus monkey induces gastric mucosa-associated lymphoid tissue lymphomas in C57BL/6 mice.
Infection and immunity 2007;75(3):1214-22.
2007: Hiromichi Ishikawa; Tomoaki Naito; Toshihiko Iwanaga; Hiromi Takahashi-Iwanaga; Makoto Suematsu; Toshifumi Hibi; Masanobu Nanno
Curriculum vitae of intestinal intraepithelial T cells: their developmental and behavioral characteristics.
Immunological reviews 2007;215():154-65.
2007: Yoichi Fujiyama; Yoshiyuki Yamagishi; Masahiro Kikuchi; Kenichiro Shimoji; Shinzo Kato; Hiroshi Nagata; Hidetsugu Saito; Toshifumi Hibi; Syunji Mishiro
[A case of fulminant hepatitis E treated with artificial liver support].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2007;104(2):219-25.
2007: Katsuyoshi Matsuoka; Yasushi Iwao; Takeshi Mori; Atsushi Sakuraba; Tomoharu Yajima; Tadakazu Hisamatsu; Susumu Okamoto; Yuichi Morohoshi; Motoko Izumiya; Hitoshi Ichikawa; Toshiro Sato; Nagamu Inoue; Haruhiko Ogata; Toshifumi Hibi
Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients.
The American journal of gastroenterology 2007;102(2):331-7.
2007: Toshihiro Nishizawa; Hidekazu Suzuki; Ayako Umezawa; Hiroe Muraoka; Eisuke Iwasaki; Tatsuhiro Masaoka; Intetsu Kobayashi; Toshifumi Hibi
Rapid detection of point mutations conferring resistance to fluoroquinolone in gyrA of Helicobacter pylori by allele-specific PCR.
Journal of clinical microbiology 2007;45(2):303-5.
2007: Toshihiro Nishizawa; Hidekazu Suzuki; Tatsuhiro Masaoka; Eisuke Iwasaki; Toshifumi Hibi
A new eradication resistance index as a predictor of metronidazole-containing second-line treatment of Helicobacter pylori.
Digestion 2007;76(3-4):215-20.
2007: Hiroki Iwai; Tadakazu Hisamatsu; Hideko Iizuka; Tokunari Oyama; Hajime Higuchi; Hiroyuki Imaeda; Haruhiko Ogata; Hiroshi Nagata; Syuji Mikami; Makio Mukai; Toshifumi Hibi
Microscopic colitis with granuloma which responded to steroid therapy.
Internal medicine (Tokyo, Japan) 2007;46(18):1551-5.
2007: Hirokazu Yokoyama; Hirose Hiroshi; Hideki Ohgo; Toshifumi Hibi; Ikuo Saito
Effects of excessive ethanol consumption on the diagnosis of the metabolic syndrome using its clinical diagnostic criteria.
Internal medicine (Tokyo, Japan) 2007;46(17):1345-52.
2007: T Yokoi; S Yamashita; Toshifumi Hibi
The nucleotide sequence and genome organization of Magnaporthe oryzae virus 1.
Archives of virology 2007;152(12):2265-9.
2007: Hidekazu Suzuki; Toshifumi Hibi; Barry J Marshall
Helicobacter pylori: present status and future prospects in Japan.
Journal of gastroenterology 2007;42(1):1-15.
2007: Tadakazu Hisamatsu; Nagamu Inoue; Tomoharu Yajima; Motoko Izumiya; Hitoshi Ichikawa; Toshifumi Hibi
Psychological aspects of inflammatory bowel disease.
Journal of gastroenterology 2007;42 Suppl 17():34-40.
2007: Toshifumi Hibi; Haruhiko Ogata
3. Metabolic syndrome and inflammatory bowel disease.
Internal medicine (Tokyo, Japan) 2007;46(2):107-8.
2006: Hiroaki Yokomori; Kazunori Yoshimura; Susumu Ohshima; Toshihiro Nagai; Kayo Fujimaki; Masahiko Nomura; Masaya Oda; Toshifumi Hibi
The endothelin-1 receptor-mediated pathway is not involved in the endothelin-1-induced defenestration of liver sinusoidal endothelial cells.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(10):1268-76.
2006: Hidekazu Suzuki; Barry J Marshall; Toshifumi Hibi
Overview: Helicobacter pylori and extragastric disease.
International journal of hematology 2006;84(4):291-300.
2006: Toshihiro Nishizawa; Hajime Higuchi; Hiromasa Takaishi; Hideko Iizuka; Motoko Izumiya; Yoshiyuki Yamagishi; Tadakazu Hisamatsu; Hidekazu Suzuki; Tatsuhiro Masaoka; Eisuke Iwasaki; Hiroshi Nagata; Toshifumi Hibi
[A case of intrahepatic cholangiocarcinoma effectively treated by hepatic arterial infusion chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2006;33(11):1657-9.
2006: Hidetsugu Saito; Shinichiro Tada; Hirotoshi Ebinuma; Hiromasa Ishii; Kazuo Kashiwazaki; Masahiko Takahashi; Nobuhiro Tsukada; Jiro Nishida; Shin Tanaka; Hiroshi Shiozaki; Toshifumi Hibi
Role of erythrocytes as a reservoir for ribavirin and relationship with adverse reactions in the early phase of interferon combination therapy for chronic hepatitis C virus infections.
Journal of clinical microbiology 2006;44(10):3562-8.
2006: Hiroyuki Imaeda; Yasushi Iwao; Haruhiko Ogata; H Ichikawa; M Mori; N Hosoe; T Masaoka; M Nakashita; H Suzuki; N Inoue; Koichi Aiura; H Nagata; Koichiro Kumai; Toshifumi Hibi
A new technique for endoscopic submucosal dissection for early gastric cancer using an external grasping forceps.
Endoscopy 2006;38(10):1007-10.
2006: Hidetsugu Saito; Shinichiro Tada; Hirotoshi Ebinuma; Hiromasa Ishii; Kazuo Kashiwazaki; Jiro Nishida; Takeshi Yoshida; Shigeyuki Zeki; Hideo Yoshida; Masahiro Yoshioka; Yasutaka Inagaki; Naoki Kumagai; Toshifumi Hibi
Induction therapy with twice-daily interferon-beta does not improve the therapeutic efficacy of consensus interferon monotherapy for chronic hepatitis C.
The Keio journal of medicine 2006;55(3):111-7.
2006: Nobuhiro Nakamoto; Hajime Higuchi; Hideaki Kanamori; Satoshi Kurita; Shinichiro Tada; Hiromasa Takaishi; Kyoko Toda; Takaya Yamada; Naoki Kumagai; Hidetsugu Saito; Toshifumi Hibi
Cyclooxygenase-2 inhibitor and interferon-beta synergistically induce apoptosis in human hepatoma cells in vitro and in vivo.
International journal of oncology 2006;29(3):625-35.
2006: Haruhiko Ogata; T Matsui; M Nakamura; M Iida; M Takazoe; Y Suzuki; Toshifumi Hibi
A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.
Gut 2006;55(9):1255-62.
2006: Hidekazu Suzuki; Tatsuhiro Masaoka; Toshifumi Hibi
[Ghrelin - a novel appetite-stimulating hormone which also affects gastrointestinal functions].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2006;48(2):82-8.
2006: Yoshinori Horie; Toshifumi Hibi; Hiromasa Ishii
[Oxidative stress and liver disease].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2006;103(7):789-96.
2006: Hidekazu Suzuki; Toshihiro Nishizawa; Toshifumi Hibi
Therapeutic strategies for functional dyspepsia and the introduction of the Rome III classification.
Journal of gastroenterology 2006;41(6):513-23.
2006: Kengo Tomita; Toshifumi Hibi
[Drug therapy for non-alcoholic steatohepatitis].
Nihon rinsho. Japanese journal of clinical medicine 2006;64(6):1146-51.
2006: Hirokazu Yokoyama; Hideki Ohgo; Hiroshi Hirose; Susumu Moriya; Toshifumi Hibi; Ikuo Saito
An inverse association between serum gamma glutamyl transpeptidase activity and Breslow's Lifestyle Index; its practical application for screening of subjects with unhealthy lifestyles.
Journal of occupational health 2006;48(3):198-206.
2006: Takanori Kanai; Toshifumi Hibi; Mamoru Watanabe
The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease.
Expert opinion on biological therapy 2006;6(5):453-66.
2006: Yuichi Morohoshi; Katsuyoshi Matsuoka; Hiroshi Chinen; Nobuhiko Kamada; Toshiro Sato; Tadakazu Hisamatsu; Susumu Okamoto; Nagamu Inoue; Hiromasa Takaishi; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi
Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.
Journal of gastroenterology 2006;41(4):318-24.
2006: Toshihiro Nishizawa; Hidekazu Suzuki; Kumiko Kurabayashi; Tatsuhiro Masaoka; Hiroe Muraoka; Mikiji Mori; Eisuke Iwasaki; Intetsu Kobayashi; Toshifumi Hibi
Gatifloxacin resistance and mutations in gyra after unsuccessful Helicobacter pylori eradication in Japan.
Antimicrobial agents and chemotherapy 2006;50(4):1538-40.
2006: K Tomita; G Tamiya; S Ando; K Ohsumi; T Chiyo; A Mizutani; N Kitamura; K Toda; T Kaneko; Yoshinori Horie; Jing-Yan Han; Shinzo Kato; M Shimoda; Y Oike; M Tomizawa; S Makino; T Ohkura; Hidetsugu Saito; Naoki Kumagai; Hiroshi Nagata; Hiromasa Ishii; Toshifumi Hibi
Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice.
Gut 2006;55(3):415-24.
2006: Hiroshi Nagata; Yasutada Akiba; Hidekazu Suzuki; Hideyuki Okano; Toshifumi Hibi
Expression of Musashi-1 in the rat stomach and changes during mucosal injury and restitution.
FEBS letters 2006;580(1):27-33.
2006: Jing-Yan Han; Yoshinori Horie; Dan Li; Yasutada Akiba; Hiroshi Nagata; Soichiro Miura; Masaya Oda; Hiromasa Ishii; Toshifumi Hibi
Attenuating effect of Myakuryu on mesenteric microcirculatory disorders induced by ischemia and reperfusion.
Clinical hemorheology and microcirculation 2006;34(1-2):145-50.
2006: Hirotoshi Ebinuma; Hidetsugu Saito; Shinichiro Tada; Nobuhiro Nakamoto; Satoshi Kurita; Kumi Kitamaura; Hitomi Horikawa; Naoki Kumagai; Kanji Tsuchimoto; Hiromasa Ishii; Toshifumi Hibi
Efficacy of natural BALL-1 interferon-alpha treatment for patients with chronic hepatitis C and a possible enhancing effect of a twice-daily starting regimen with interferon-beta.
Hepato-gastroenterology 2006;53(67):94-9.
2006: Toshifumi Hibi; Haruhiko Ogata
Novel pathophysiological concepts of inflammatory bowel disease.
Journal of gastroenterology 2006;41(1):10-6.
2006: Hidetsugu Saito; Hirokazu Yokoyama; Toshifumi Hibi
[Superoxide anion and reactive oxygen species and redox regulation in the liver].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2006;103(1):15-22.
2006: Haruko Shiraishi-Yokoyama; Hirokazu Yokoyama; Michinaga Matsumoto; Hiroyuki Imaeda; Toshifumi Hibi
Acetaldehyde inhibits the formation of retinoic acid from retinal in the rat esophagus.
Scandinavian journal of gastroenterology 2006;41(1):80-6.
2005: Yoshinori Horie; Hiromasa Ishii; Toshifumi Hibi
Severe alcoholic hepatitis in Japan: prognosis and therapy.
Alcoholism, clinical and experimental research 2005;29(12 Suppl):251S-8S.
2005: Kengo Tomita; Gen Tamiya; Satoshi Ando; Naoto Kitamura; Haruna Koizumi; Shinzo Kato; Yoshinori Horie; Takehiko Kaneko; Toshifumi Azuma; Hiroshi Nagata; Hiromasa Ishii; Toshifumi Hibi
AICAR, an AMPK activator, has protective effects on alcohol-induced fatty liver in rats.
Alcoholism, clinical and experimental research 2005;29(12 Suppl):240S-5S.
2005: Yoshiyuki Yamagishi; Hidetsugu Saito; Shinichiro Tada; Yoshinori Horie; Shinzo Kato; Hiromasa Ishii; Naoki Shimojima; Junko Haga; Motohide Shimazu; Masaki Kitajima; Toshifumi Hibi
Value of computed tomography-derived estimated liver volume/standard liver volume ratio for predicting the prognosis of adult fulminant hepatic failure in Japan.
Journal of gastroenterology and hepatology 2005;20(12):1843-9.
2005: Nobuhiko Kamada; Tadakazu Hisamatsu; Susumu Okamoto; Toshiro Sato; Katsuyoshi Matsuoka; Kumiko Arai; Takaaki Nakai; Akira Hasegawa; Nagamu Inoue; Noriaki Watanabe; Kiyoko S Akagawa; Toshifumi Hibi
Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6900-8.
2005: Tatsuhiro Masaoka; Hidekazu Suzuki; Toshifumi Hibi
[Eradication therapy for the improvement of quality of life in cases of Helicobacter pylori-positive functional dyspepsia].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 11():474-7.
2005: Hidekazu Suzuki; Tatsuhiro Masaoka; Gen Sakai; Hiromasa Ishii; Toshifumi Hibi
Improvement of gastrointestinal quality of life scores in cases of Helicobacter pylori-positive functional dyspepsia after successful eradication therapy.
Journal of gastroenterology and hepatology 2005;20(11):1652-60.
2005: Osamu Hitotsumatsu; Hiromasa Hamada; Makoto Naganuma; Nagamu Inoue; Hiromasa Ishii; Toshifumi Hibi; Hiromichi Ishikawa
Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.
Journal of gastroenterology 2005;40(10):956-63.
2005: Hidehiko Matsukawa; Takanori Kanai; Makoto Naganuma; Nobuhiko Kamada; Tadakazu Hisamatsu; Hiromasa Takaishi; Haruhiko Ogata; Makio Mukai; Hiromasa Ishii; Tsuneyo Mimori; Mamoru Watanabe; Toshifumi Hibi
A novel apoptosis-inducing monoclonal antibody (anti-LHK) against a cell surface antigen on colon cancer cells.
Journal of gastroenterology 2005;40(10):945-55.
2005: Yoshimasa Saito; Hidetsugu Saito; Shinichiro Tada; Nobuhiro Nakamoto; Hitomi Horikawa; Satoshi Kurita; Kumi Kitamura; Hirotoshi Ebinuma; Hiromasa Ishii; Toshifumi Hibi
Effect of long-term interferon therapy for refractory chronic hepatitis c: preventive effect on hepatocarcinogenesis.
Hepato-gastroenterology 2005;52(65):1491-6.
2005: T Sato; T Nakai; N Tamura; Shin-ichiro Okamoto; Katsuyoshi Matsuoka; A Sakuraba; T Fukushima; T Uede; Toshifumi Hibi
Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.
Gut 2005;54(9):1254-62.
2005: Michinaga Matsumoto; Hirokazu Yokoyama; Hidekazu Suzuki; Haruko Shiraishi-Yokoyama; Toshifumi Hibi
Retinoic acid formation from retinol in the human gastric mucosa: role of class IV alcohol dehydrogenase and its relevance to morphological changes.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(3):G429-33.
2005: Yoshiyuki Yamagishi; Yasutada Akiba; Motoko Izumiya; Hajime Higuchi; Hideko Iizuka; Hiromasa Takaishi; Hiroshi Nagata; Toshifumi Hibi
[A case of advanced gastric cancer with lymphangitis carcinomatosa after operation of Krukenberg tumor treated by TS-1 plus CPT-11 as third-line chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(8):1167-70.
2005: Yuka Abiko; Hidekazu Suzuki; Tatsuhiro Masaoka; Sachiko Nomura; Kumiko Kurabayashi; Hiroshi Hosoda; Kenji Kangawa; Toshifumi Hibi
Enhanced plasma ghrelin levels in Helicobacter pylori-colonized, interleukin-1-receptor type 1-homozygous knockout (IL-1R1-/-) mice.
World journal of gastroenterology : WJG 2005;11(27):4148-53.
2005: Seiichiro Fukuhara; Hidekazu Suzuki; Tatsuhiro Masaoka; Mamoru Arakawa; Hiroshi Hosoda; Yuriko Minegishi; Kenji Kangawa; Hiromasa Ishii; Masaki Kitajima; Toshifumi Hibi
Enhanced ghrelin secretion in rats with cysteamine-induced duodenal ulcers.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(1):G138-45.
2005: Hiroaki Yokomori; Masaya Oda; Go Wakabayashi; Masaki Kitajima; Kazunori Yoshimura; Masahiko Nomura; Toshifumi Hibi
High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis.
World journal of gastroenterology : WJG 2005;11(24):3710-3.
2005: Tomoko Matsumoto; Ryuichi Okamoto; Tomoharu Yajima; Takehiko Mori; Shinichiro Okamoto; Yasuo Ikeda; Makio Mukai; Motomi Yamazaki; Shigeru Oshima; Kiichiro Tsuchiya; Tetsuya Nakamura; Takanori Kanai; Hideyuki Okano; Johji Inazawa; Toshifumi Hibi; Mamoru Watanabe
Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.
Gastroenterology 2005;128(7):1851-67.
2005: Hidekazu Suzuki; Yuriko Minegishi; Yohei Nomoto; Takayuki Ota; Tatsuhiro Masaoka; Gijs R van den Brink; Toshifumi Hibi
Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori-infected Mongolian gerbils.
The Journal of pathology 2005;206(2):186-97.
2005: Toshifumi Hibi; Atsushi Sakuraba
Is there a role for apheresis in gastrointestinal disorders?
Nature clinical practice. Gastroenterology & hepatology 2005;2(5):200-1.
2005: Katsuyoshi Matsuoka; Toshifumi Hibi
[Ulcerative colitis and Crohn's disease].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 5():507-11.
2005: Shinichiro Tada; Hidetsugu Saito; Toshifumi Hibi
[Primary sclerosing cholangitis].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 5():501-6.
2005: Tadakazu Hisamatsu; Toshifumi Hibi
[Immunosuppressants for therapy of patients with ulcerative colitis].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(5):831-5.
2005: Hideko Iizuka; Hiromasa Takaishi; Toshifumi Hibi
[Probiotics for inflammatory bowel disease].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(5):776-80.
2005: Yasushi Iwao; Katsuyoshi Matsuoka; Haruhiko Ogata; Toshifumi Hibi
[Endoscopic diagnosis of colitic cancer and dysplasia].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(5):738-9.
2005: Nobuhiko Kamada; Nagamu Inoue; Tadakazu Hisamatsu; Susumu Okamoto; Katsuyoshi Matsuoka; Toshiro Sato; Hiroshi Chinen; Kyong Su Hong; Takaya Yamada; Yumiko Suzuki; Tatsuo Suzuki; Noriaki Watanabe; Kanji Tsuchimoto; Toshifumi Hibi
Nonpathogenic Escherichia coli strain Nissle1917 prevents murine acute and chronic colitis.
Inflammatory bowel diseases 2005;11(5):455-63.
2005: Hidetsugu Saito; Shinichiro Tada; Nobuhiro Nakamoto; Kumi Kitamura; Hitomi Horikawa; Satoshi Kurita; Hirotoshi Ebinuma; Hiromasa Ishii; Masahiko Takahashi; Shin Tanaka; Toshifumi Hibi
Contribution of Irf-1 promoter polymorphisms to the Th1-type cell response and interferon-beta monotherapy for chronic hepatitis C.
Hepatology research : the official journal of the Japan Society of Hepatology 2005;32(1):25-32.
2005: Toshiyuki Tahara; Nagamu Inoue; Tadakazu Hisamatsu; Kazuhiro Kashiwagi; Hiromasa Takaishi; Takanori Kanai; Mamoru Watanabe; Hiromasa Ishii; Toshifumi Hibi
Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.
Journal of gastroenterology and hepatology 2005;20(5):710-5.
2005: Yoshiro Saikawa; Tetsuro Kubota; Tsunehiro Takahashi; Yukako Akatsu; Rieko Nakamura; Masashi Yoshida; Naoyuki Shigematsu; Yoshihide Otani; Koichiro Kumai; Toshifumi Hibi; Masaki Kitajima
Is chemoradiation effective or harmful for stage VI gastric cancer patients?
Oncology reports 2005;13(5):865-70.
2005: Shunsuke Komoto; Soichiro Miura; Seiichiro Koseki; M Goto; Satoshi Hachimura; Hitoshi Fujimori; Ryota Hokari; Yuriko Hara; Takashi Ogino; Chikako Watanabe; Hiroshi Nagata; Shuichi Kaminogawa; Toshifumi Hibi; Hiromasa Ishii
Effect of specific antigen stimulation on intraepithelial lymphocyte migration to small intestinal mucosa.
Clinical and experimental immunology 2005;140(2):249-57.
2005: Eriko Okada; Motomi Yamazaki; Masanobu Tanabe; Tsutomu Takeuchi; Masanobu Nanno; Shigeru Oshima; Ryuichi Okamoto; Kiichiro Tsuchiya; Tetsuya Nakamura; Takanori Kanai; Toshifumi Hibi; Mamoru Watanabe
IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(4):G745-54.
2005: Ken Teramoto; Soichiro Miura; Yoshikazu Tsuzuki; Ryota Hokari; Chikako Watanabe; T Inamura; T Ogawa; Naoki Hosoe; Hiroshi Nagata; Hiromasa Ishii; Toshifumi Hibi
Increased lymphocyte trafficking to colonic microvessels is dependent on MAdCAM-1 and C-C chemokine mLARC/CCL20 in DSS-induced mice colitis.
Clinical and experimental immunology 2005;139(3):421-8.
2005: Sachiko Nomura; Hidekazu Suzuki; Tatsuhiro Masaoka; Kumiko Kurabayashi; Hiromasa Ishii; Masaki Kitajima; Kikuo Nomoto; Toshifumi Hibi
Effect of dietary anti-urease immunoglobulin Y on Helicobacter pylori infection in Mongolian gerbils.
Helicobacter 2005;10(1):43-52.
2005: Yoshinori Horie; Jing-Yan Han; Shuka Mori; Masahiro Konishi; Mikio Kajihara; Takehiko Kaneko; Yoshiyuki Yamagishi; Shinzo Kato; Hiromasa Ishii; Toshifumi Hibi
Herbal cardiotonic pills prevent gut ischemia/reperfusion-induced hepatic microvascular dysfunction in rats fed ethanol chronically.
World journal of gastroenterology : WJG 2005;11(4):511-5.
2005: Tatsuhiro Masaoka; Hidekazu Suzuki; Hiroyuki Imaeda; Hiroshi Hosoda; Tadashi Ohara; Tetsuo Morishita; Hiromasa Ishii; Kenji Kangawa; Toshifumi Hibi
Long-term strict monitoring of plasma ghrelin and other serological markers of gastric diseases after Helicobacter pylori eradication.
Hepato-gastroenterology 2005;52(61):1-4.
2005: Hidekazu Suzuki; Toshifumi Hibi
Novel effects other than antisecretory action and off-label use of proton pump inhibitors.
Expert opinion on pharmacotherapy 2005;6(1):59-67.
2005: Kanji Wakabayashi; Hidetsugu Saito; Fumihiko Kaneko; Nobuhiro Nakamoto; Shinichiro Tada; Toshifumi Hibi
Gene expression associated with the decrease in malignant phenotype of human liver cancer cells following stimulation with a histone deacetylase inhibitor.
International journal of oncology 2005;26(1):233-9.
2004: Toshihiro Nagai; Hiroaki Yokomori; Kazunori Yoshimura; Kayo Fujimaki; Masahiko Nomura; Toshifumi Hibi; Masaya Oda
Actin filaments around endothelial fenestrae in rat hepatic sinusoidal endothelial cells.
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 2004;37(4):252-5.
2004: Hiroshi Nagata; Tsunenori Arai; Yusuke Soejima; Hidekazu Suzuki; Hiromasa Ishii; Toshifumi Hibi
Limited capability of regional lymph nodes to eradicate metastatic cancer cells.
Cancer research 2004;64(22):8239-48.
2004: Kengo Tomita; Toshifumi Azuma; Naoto Kitamura; Gen Tamiya; Satoshi Ando; Hiroshi Nagata; Shinzo Kato; Sayaka Inokuchi; Takeshi Nishimura; Hiromasa Ishii; Toshifumi Hibi
Leptin deficiency enhances sensitivity of rats to alcoholic steatohepatitis through suppression of metallothionein.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(5):G1078-85.
2004: Hidekazu Suzuki; Tatsuhiro Masaoka; Hiroshi Hosoda; Sachiko Nomura; Tadashi Ohara; Kenji Kangawa; Hiromasa Ishii; Toshifumi Hibi
Plasma ghrelin concentration correlates with the levels of serum pepsinogen I and pepsinogen I/II ratio--a possible novel and non-invasive marker for gastric atrophy.
Hepato-gastroenterology 2004;51(59):1249-54.
2004: Katsuyoshi Matsuoka; Nagamu Inoue; Toshiro Sato; Susumu Okamoto; Tadakazu Hisamatsu; Y Kishi; Atsushi Sakuraba; Osamu Hitotsumatsu; Haruhiko Ogata; K Koganei; T Fukushima; Takanori Kanai; Masahiko Watanabe; Hiromasa Ishii; Toshifumi Hibi
T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease.
Gut 2004;53(9):1303-8.
2004: Yasutada Akiba; Shinichi Kato; Ken-ichi Katsube; Masahiko Nakamura; Koji Takeuchi; Hiromasa Ishii; Toshifumi Hibi
Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats.
Biochemical and biophysical research communications 2004;321(1):219-25.
2004: Hidekazu Suzuki; S Nomura; Tatsuhiro Masaoka; H Goshima; N Kamata; Y Kodama; Hiromasa Ishii; Masaki Kitajima; K Nomoto; Toshifumi Hibi
Effect of dietary anti-Helicobacter pylori-urease immunoglobulin Y on Helicobacter pylori infection.
Alimentary pharmacology & therapeutics 2004;20 Suppl 1():185-92.
2004: Norio Maeda; Mamoru Watanabe; Susumu Okamoto; Takanori Kanai; Taketo Yamada; Jun-Ichi Hata; Nobumichi Hozumi; Asao Katsume; Hideko Nuriya; Jasbir Sandhu; Hiromasa Ishii; Michinori Kohara; Toshifumi Hibi
Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone.
Liver international : official journal of the International Association for the Study of the Liver 2004;24(3):259-67.
2004: Makoto Naganuma; Shinsuke Funakoshi; Atsushi Sakuraba; Hanae Takagi; Nagamu Inoue; Haruhiko Ogata; Yasushi Iwao; Hiromasa Ishi; Toshifumi Hibi
Granulocytapheresis is useful as an alternative therapy in patients with steroid-refractory or -dependent ulcerative colitis.
Inflammatory bowel diseases 2004;10(3):251-7.
2004: Akira Okazawa; Takanori Kanai; K Nakamaru; Toshiro Sato; Nagamu Inoue; Haruhiko Ogata; Yasushi Iwao; M Ikeda; T Kawamura; Shin Makita; Koji Uraushihara; Ryuichi Okamoto; Motomi Yamazaki; M Kurimoto; Hiromasa Ishii; Masahiko Watanabe; Toshifumi Hibi
Human intestinal epithelial cell-derived interleukin (IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.
Clinical and experimental immunology 2004;136(2):269-76.
2004: Yasutada Akiba; Yoshiyuki Yamagishi; Syuka Mori; Tomoki Ueda; Junji Suzuki; Naoki Hosoe; Motoko Izumiya; Hiromasa Takaishi; Hiroshi Nagata; Toshifumi Hibi; Hiromasa Ishii
[A case of recurrent pleural effusion and positive cytology of advanced gastric cancer treated by TS-1 plus weekly taxane as second-line chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(3):453-6.
2004: Toshiro Sato; Takanori Kanai; Mamoru Watanabe; Atsushi Sakuraba; Susumu Okamoto; Takaaki Nakai; Akira Okazawa; Nagamu Inoue; Teruji Totsuka; Motomi Yamazaki; Richard A Kroczek; Tsuneo Fukushima; Hiromasa Ishii; Toshifumi Hibi
Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.
Gastroenterology 2004;126(3):829-39.
2004: Toshifumi Hibi; Shigeo Yoshizawa
[Anti tumor necrosis factor-alpha antibody: biological significance and therapeutic target for Crohn's disease].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2004;27(1):16-21.
2004: Takehiko Mori; S Mori; Y Kanda; Kazuaki Yakushiji; Shin Mineishi; Yoichi Takaue; Hisashi Gondo; Mine Harada; H Sakamaki; Tomoharu Yajima; Yasushi Iwao; Toshifumi Hibi; Shinichiro Okamoto
Clinical significance of cytomegalovirus (CMV) antigenemia in the prediction and diagnosis of CMV gastrointestinal disease after allogeneic hematopoietic stem cell transplantation.
Bone marrow transplantation 2004;33(4):431-4.
2004: Hiroaki Nohara; Naoko Okayama; Nagamu Inoue; Yuji Koike; Kozue Fujimura; Yutaka Suehiro; Yuichiro Hamanaka; Shingo Higaki; Hideo Yanai; Tomoharu Yoshida; Toshifumi Hibi; Kiwamu Okita; Yuji Hinoda
Association of the -173 G/C polymorphism of the macrophage migration inhibitory factor gene with ulcerative colitis.
Journal of gastroenterology 2004;39(3):242-6.
2004: Shinichi Futei; Yoshinori Sugino; Sachio Kuribayashi; Yutaka Imai; Fumiaki Ueno; Toshifumi Hibi; Toru Mitsushima
[New preparation method for barium enema: efficacy and administration of oral intestinal lavage solution with gastrointestinal prokinetic agent].
Nihon Igaku Hōshasen Gakkai zasshi. Nippon acta radiologica 2004;64(1):22-30.
2003: Hiroaki Nohara; Nagamu Inoue; Toshifumi Hibi; Kiwamu Okita; Yuji Hinoda
Association between the interleukin-1 receptor antagonist polymorphism and ulcerative colitis with younger age at diagnosis.
Immunology letters 2003;90(1):53-7.
2003: Tsunehiro Takahashi; Yoshiro Saikawa; Tetsuro Kubota; Yasutada Akiba; Naoyuki Shigematsu; Masashi Yoshida; Yoshihide Otani; Koichiro Kumai; Toshifumi Hibi; Masaki Kitajima
Histological complete response in a case of advanced gastric cancer treated by chemotherapy with S-1 plus low-dose cisplatin and radiation.
Japanese journal of clinical oncology 2003;33(11):584-8.
2003: H Takagi; Takanori Kanai; Akira Okazawa; Y Kishi; Toshiro Sato; Hiromasa Takaishi; Nagamu Inoue; Haruhiko Ogata; Yasushi Iwao; K Hoshino; Kiyoshi Takeda; Shizuo Akira; Masahiko Watanabe; Hiromasa Ishii; Toshifumi Hibi
Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice.
Scandinavian journal of gastroenterology 2003;38(8):837-44.
2003: Motomi Yamazaki; Tomoharu Yajima; Masanobu Tanabe; Kazuto Fukui; Eriko Okada; Ryuichi Okamoto; Shigeru Oshima; Tetsuya Nakamura; Takanori Kanai; Masahiro Uehira; Tsutomu Takeuchi; Hiromichi Ishikawa; Toshifumi Hibi; Mamoru Watanabe
Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1556-63.
2003: Takahiro Ishikura; Takanori Kanai; Koji Uraushihara; Ryoichi Iiyama; Shin Makita; Teruji Totsuka; Motomi Yamazaki; Taisuke Sawada; Tetsuya Nakamura; Tatsuya Miyata; Tetsuji Kitahora; Toshifumi Hibi; Tomoaki Hoshino; Mamoru Watanabe
Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice.
Journal of gastroenterology and hepatology 2003;18(8):960-9.
2003: Motoko Izumiya; Tomoharu Yajima; Hiroshi Serizawa; Noriaki Watanabe; Yoshiki Hamada; Satoshi Tsunematsu; Naoki Kumagai; Kanji Tsuchimoto; Hajime Toyoda; Toshifumi Hibi; Hiromasa Ishii
[A case of Crohn's disease complicated with hepatocellular carcinoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2003;100(7):858-62.
2003: Toshihiko Ezaki; Mamoru Watanabe; Nagamu Inoue; Takanori Kanai; Haruhiko Ogata; Yasushi Iwao; Hiromasa Ishii; Toshifumi Hibi
A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.
Cancer research 2003;63(13):3747-9.
2003: Takanori Kanai; Koji Uraushihara; Teruji Totsuka; Akira Okazawa; Toshifumi Hibi; Shigeru Oshima; Tatsuya Miyata; Tetsuya Nakamura; Mamoru Watanabe
Macrophage-derived IL-18 targeting for the treatment of Crohn's disease.
Current drug targets. Inflammation and allergy 2003;2(2):131-6.
2003: Toshifumi Hibi
Molecular biological studies of the pathogenesis in inflammatory bowel disease.
Internal medicine (Tokyo, Japan) 2003;42(3):285-7.
2003: Toshifumi Hibi; Nagamu Inoue; Haruhiko Ogata; Makoto Naganuma
Introduction and overview: recent advances in the immunotherapy of inflammatory bowel disease.
Journal of gastroenterology 2003;38 Suppl 15():36-42.
2003: Yasutada Akiba; Chikako Watanabe; Yasuhiro Takada; Kotaro Naito; Daisuke Aoki; Makio Mukai; Shinzo Kato; Toshifumi Hibi; Hiromasa Ishii
[A case of type 4 gastric cancer, diagnosed after operation for Krukenberg's tumor, treated by TS-1 plus low-dose cisplatinum].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(2):277-81.
2003: Tadao Bamba; Takashi Shimoyama; Masaya Sasaki; Tomoyuki Tsujikawa; Yoshihiro Fukuda; Kazutaka Koganei; Toshifumi Hibi; Yasushi Iwao; Akihiro Munakata; Shinsaku Fukuda; Takayuki Matsumoto; Nobuhide Oshitani; Nobuo Hiwatashi; Tatsuo Oriuchi; Tetsuji Kitahora; Toshinori Utsunomiya; Yasushi Saitoh; Yasuo Suzuki; Mitsuyoshi Nakajima
Dietary fat attenuates the benefits of an elemental diet in active Crohn's disease: a randomized, controlled trial.
European journal of gastroenterology & hepatology 2003;15(2):151-7.
2003: Teruji Totsuka; Takanori Kanai; Ryoichi Iiyama; Koji Uraushihara; Motomi Yamazaki; Ryuichi Okamoto; Toshifumi Hibi; Katsunari Tezuka; Miyuki Azuma; Hisaya Akiba; Hideo Yagita; Ko Okumura; Mamoru Watanabe
Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis.
Gastroenterology 2003;124(2):410-21.
2003: Nobunari Yoshimizu; Yoshiro Saikawa; Tetsuro Kubota; Yasutada Akiba; Masashi Yoshida; Yoshihide Otani; Koichiro Kumai; Toshifumi Hibi; Masaki Kitajima
Complete response of a highly advanced gastric carcinoma to preoperative chemoradiotherapy with S-1 and low-dose cisplatin.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2003;6(3):185-90.
2003: Toshifumi Hibi; Makoto Naganuma; Tetsuji Kitahora; Fukunori Kinjyo; Takashi Shimoyama
Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis.
Journal of gastroenterology 2003;38(8):740-6.
2003: Haruhiko Ogata; Toshifumi Hibi
Cytokine and anti-cytokine therapies for inflammatory bowel disease.
Current pharmaceutical design 2003;9(14):1107-13.
2002: Akira Okazawa; Takanori Kanai; Mamoru Watanabe; Motomi Yamazaki; Nagamu Inoue; Masao Ikeda; Masashi Kurimoto; Hiromasa Ishii; Toshifumi Hibi
Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement.
The American journal of gastroenterology 2002;97(12):3108-17.
2002: Ryuichi Okamoto; Tomoharu Yajima; Motomi Yamazaki; Takanori Kanai; Makio Mukai; Shinichiro Okamoto; Yasuo Ikeda; Toshifumi Hibi; Johji Inazawa; Mamoru Watanabe
Damaged epithelia regenerated by bone marrow-derived cells in the human gastrointestinal tract.
Nature medicine 2002;8(9):1011-7.
2002: Masahiko Watanabe; Hirotoshi Hasegawa; Seiichiro Yamamoto; Toshifumi Hibi; Masaki Kitajima
Successful application of laparoscopic surgery to the treatment of Crohn's disease with fistulas.
Diseases of the colon and rectum 2002;45(8):1057-61.
2002: Koichi Kobayashi; Haruhiko Ogata; M Morikawa; S Iijima; N Harada; T Yoshida; W R Brown; Nagamu Inoue; Y Hamada; Hiromasa Ishii; Masahiko Watanabe; Toshifumi Hibi
Distribution and partial characterisation of IgG Fc binding protein in various mucin producing cells and body fluids.
Gut 2002;51(2):169-76.
2002: Makoto Naganuma; Mamoru Watanabe; Takanori Kanai; Yasushi Iwao; Makio Mukai; Hiromasa Ishii; Toshifumi Hibi
Characterization of structures with T-lymphocyte aggregates in ileal villi of Crohn's disease.
The American journal of gastroenterology 2002;97(7):1741-7.
2002: Nagamu Inoue; Kazuo Tamura; Yoshitaka Kinouchi; Yoshihiro Fukuda; Seiichi Takahashi; Yasunori Ogura; Naohiro Inohara; Gabriel Núñez; Yusuke Kishi; Yuji Koike; Tooru Shimosegawa; Takashi Shimoyama; Toshifumi Hibi
Lack of common NOD2 variants in Japanese patients with Crohn's disease.
Gastroenterology 2002;123(1):86-91.
2002: Takehiko Mori; Shinichiro Okamoto; Reiko Watanabe; Tomoharu Yajima; Yasushi Iwao; Rie Yamazaki; Tomonori Nakazato; N Sato; T Iguchi; H Nagayama; Nobuyuki Takayama; Toshifumi Hibi; Yasuo Ikeda
Dose-adjusted preemptive therapy for cytomegalovirus disease based on real-time polymerase chain reaction after allogeneic hematopoietic stem cell transplantation.
Bone marrow transplantation 2002;29(9):777-82.
2002: Toshifumi Hibi; Shigeo Yoshizawa
[Infliximab(chimeric monoclonal antibody to tumor necrosis factor alpha)].
Nihon rinsho. Japanese journal of clinical medicine 2002;60(3):480-6.
2002: Toshifumi Hibi; Haruhiko Ogata; Atsushi Sakuraba
Animal models of inflammatory bowel disease.
Journal of gastroenterology 2002;37(6):409-17.
2002: Makoto Naganuma; Yasushi Iwao; Kazuhiro Kashiwagi; Shinsuke Funakoshi; Hiromasa Ishii; Toshifumi Hibi
A case of Behçet's disease accompanied by colitis with longitudinal ulcers and granuloma.
Journal of gastroenterology and hepatology 2002;17(1):105-8.
2001: Takashi Sunagawa; Yoshimasa Yonamine; Fukunori Kinjo; Masahiko Watanabe; Toshifumi Hibi; Atsushi Saito
HLA class-I-restricted and colon-specific cytotoxic T cells from lamina propria lymphocytes of patients with ulcerative colitis.
Journal of clinical immunology 2001;21(6):381-9.
2001: Takanori Kanai; Masahiko Watanabe; Akira Okazawa; Toshiro Sato; Motomi Yamazaki; Shinichiro Okamoto; Hiromasa Ishii; Teruji Totsuka; Ryoichi Iiyama; Ryuichi Okamoto; M Ikeda; M Kurimoto; Kiyoshi Takeda; Shizuo Akira; Toshifumi Hibi
Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease.
Gastroenterology 2001;121(4):875-88.
2001: Makoto Naganuma; Yasushi Iwao; Haruhiko Ogata; Nagamu Inoue; Shinsuke Funakoshi; S Yamamoto; Y Nakamura; Hiromasa Ishii; Toshifumi Hibi
Measurement of colonic mucosal concentrations of 5-aminosalicylic acid is useful for estimating its therapeutic efficacy in distal ulcerative colitis: comparison of orally administered mesalamine and sulfasalazine.
Inflammatory bowel diseases 2001;7(3):221-5.
2001: Hitoshi Asakura; T Yao; T Matsui; Kazutaka Koganei; T Fukushima; Masakazu Takazoe; R Hobara; H Nakano; S Okamura; K Matsueda; H Kashida; K Makiyama; N Hiwatashi; K Kashiwagi; Toshifumi Hibi
Efficacy of treatment with chimeric monoclonal antibody (Infliximab) to tumor necrosis factor-alpha for Crohn's disease in Japan: evaluation by rapid turnover proteins, and radiologic and endoscopic findings.
Journal of gastroenterology and hepatology 2001;16(7):763-9.
2001: Nagamu Inoue; Masahiko Watanabe; Toshiro Sato; Akira Okazawa; Motomi Yamazaki; Takanori Kanai; Haruhiko Ogata; Yasushi Iwao; Hiromasa Ishii; Toshifumi Hibi
Restricted V(H) gene usage in lamina propria B cells producing anticolon antibody from patients with ulcerative colitis.
Gastroenterology 2001;121(1):15-23.
2001: A Nakazawa; Toshifumi Hibi
[Home nutrition therapy for Crohn's disease].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 5():884-8.
2001: Y Fukuda; Hiroshi Serizawa; T Yajima; Noriaki Watanabe; Yoshiki Hamada; Naoki Kumagai; Kanji Tsuchimoto; K Kameyama; Toshifumi Hibi; Hiromasa Ishii
[A case of ulcerative colitis complicated with rectovaginal fistula causing perianal abscess].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2001;98(5):544-8.
2001: Toshifumi Hibi; Nagamu Inoue
[The pathogenesis of inflammatory bowel disease viewed from immunological aspects].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2001;98(4):390-8.
2001: Makoto Naganuma; B Iizuka; A Torii; T Ogihara; Y Kawamura; M Ichinose; Y Kojima; Toshifumi Hibi
Appendectomy protects against the development of ulcerative colitis and reduces its recurrence: results of a multicenter case-controlled study in Japan.
The American journal of gastroenterology 2001;96(4):1123-6.
2001: Makoto Naganuma; Yasushi Iwao; Haruhiko Ogata; Shinsuke Funakoshi; H Takagi; M Nakano; Osamu Hitotsumatsu; T Ezaki; Tadakazu Hisamatsu; Nagamu Inoue; Toshifumi Hibi; Hiromasa Ishii
[Efficacy of mesalamine enema in the treatment of steroid-resistant or dependent distal ulcerative colitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2001;98(2):151-6.
2001: Takanori Kanai; Masahiko Watanabe; Akira Okazawa; Toshiro Sato; Toshifumi Hibi
Interleukin-18 and Crohn's disease.
Digestion 2001;63 Suppl 1():37-42.
2000: Toshiki Watanabe; Toshifumi Hibi
[RNA-dependent RNA polymerases of plant plus-sense single-stranded RNA viruses].
Uirusu 2000;50(2):217-32.
2000: Toshifumi Hibi; Takanori Kanai; Masahiko Watanabe; S Okazawa; Toshiro Sato
[The role of IL-18 on the pathogenesis of Crohn's disease].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2000;23(6):607-10.
2000: Takanori Kanai; Masahiko Watanabe; Akira Okazawa; K Nakamaru; M Okamoto; M Naganuma; Hiromasa Ishii; M Ikeda; M Kurimoto; Toshifumi Hibi
Interleukin 18 is a potent proliferative factor for intestinal mucosal lymphocytes in Crohn's disease.
Gastroenterology 2000;119(6):1514-23.
2000: K Suzuki; Takatoku Oida; Hiromasa Hamada; O Hitotsumatsu; Masahiko Watanabe; Toshifumi Hibi; Hiroshi Yamamoto; E Kubota; Shuichi Kaminogawa; Hiromichi Ishikawa
Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis.
Immunity 2000;13(5):691-702.
2000: Makoto Naganuma; Yasushi Iwao; Nagamu Inoue; Tadakazu Hisamatsu; Hiroyuki Imaeda; Hiromasa Ishii; Takanori Kanai; Masahiko Watanabe; Toshifumi Hibi
Analysis of clinical course and long-term prognosis of surgical and nonsurgical patients with intestinal Behçet's disease.
The American journal of gastroenterology 2000;95(10):2848-51.
2000: K Kashiwagi; Masahiko Watanabe; T Ezaki; Takanori Kanai; Hiromasa Ishii; Makio Mukai; Toshifumi Hibi
Clinical usefulness of microsatellite instability for the prediction of gastric adenoma or adenocarcinoma in patients with chronic gastritis.
British journal of cancer 2000;82(11):1814-8.
2000: Takanori Kanai; Masahiko Watanabe; A Hayashi; A Nakazawa; T Yajima; Akira Okazawa; Motomi Yamazaki; Hiromasa Ishii; Toshifumi Hibi
Regulatory effect of interleukin-4 and interleukin-13 on colon cancer cell adhesion.
British journal of cancer 2000;82(10):1717-23.
2000: Takehiko Mori; Shinichiro Okamoto; S Matsuoka; Tomoharu Yajima; M Wakui; Reiko Watanabe; Akaru Ishida; Yasushi Iwao; M Mukai; Toshifumi Hibi; Yasuo Ikeda
Risk-adapted pre-emptive therapy for cytomegalovirus disease in patients undergoing allogeneic bone marrow transplantation.
Bone marrow transplantation 2000;25(7):765-9.
2000: M Nakano; Toshifumi Hibi
[Crohn's disease].
Ryōikibetsu shōkōgun shirīzu 2000;(31):209-12.
2000: Toshifumi Hibi; H Takagi
[Ulcerative colitis].
Ryōikibetsu shōkōgun shirīzu 2000;(31):204-8.
2000: Y Takemoto; T Kanehira; M Shinohara; S Yamashita; Toshifumi Hibi
The nucleotide sequence and genome organization of Japanese iris necrotic ring virus, a new species in the genus Carmovirus.
Archives of virology 2000;145(3):651-7.
2000: K Toda; Naoki Kumagai; Kanji Tsuchimoto; H Inagaki; T Suzuki; T Oishi; Kazuhiro Atsukawa; Hidetsugu Saito; Toshio Morizane; Toshifumi Hibi; Hiromasa Ishii
Induction of hepatic stellate cell proliferation by LPS-stimulated peripheral blood mononuclear cells from patients with liver cirrhosis.
Journal of gastroenterology 2000;35(3):214-20.
2000: Hiromasa Takaishi; S Ohara; Kyoko Hotta; Tomoharu Yajima; Takanori Kanai; Nagamu Inoue; Yasushi Iwao; Masahiko Watanabe; Hiromasa Ishii; Toshifumi Hibi
Circulating autoantibodies against purified colonic mucin in ulcerative colitis.
Journal of gastroenterology 2000;35(1):20-7.
1999: Tadakazu Hisamatsu; Mamoru Watanabe; Haruhiko Ogata; T Ezaki; S Hozawa; Hiromasa Ishii; Takanori Kanai; Toshifumi Hibi
Interferon-inducible gene family 1-8U expression in colitis-associated colon cancer and severely inflamed mucosa in ulcerative colitis.
Cancer research 1999;59(23):5927-31.
1999: T Yokoi; Yutaka Takemoto; Masashi Suzuki; Shuichi Yamashita; Toshifumi Hibi
The nucleotide sequence and genome organization of Sclerophthora macrospora virus B.
Virology 1999;264(2):344-9.
1999: K Miyazaki; Tadakazu Hisamatsu; H Ebinuma; Kazuhiro Kashiwagi; Tomoharu Yajima; Hiromasa Takaishi; Yasushi Iwao; Masahiko Watanabe; Toshifumi Hibi; Hiromasa Ishii
[Intravenous cyclosporine therapy for ulcerative colitis refractory to steroid therapy].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1999;96(11):1290-4.
1999: A Nakazawa; Masahiko Watanabe; Takanori Kanai; Tomoharu Yajima; Motomi Yamazaki; Haruhiko Ogata; Hiromasa Ishii; M Azuma; Toshifumi Hibi
Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa.
Gastroenterology 1999;117(3):536-45.
1999: Masako Kohyama; Masanobu Nanno; M Kawaguchi-Miyashita; Shin-ichiro Shimada; Masahiko Watanabe; Toshifumi Hibi; Shuichi Kaminogawa; Hiromichi Ishikawa
Cytolytic and IFN-gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are T cell receptor-beta-chain dependent.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7451-5.
1999: Makoto Naganuma; Yasushi Iwao; Soichiro Miura; I Okamoto; Y Ohkura; Takanori Kanai; Masahiko Watanabe; Toshifumi Hibi; Hiromasa Ishii
[A case of well differentiated adenocarcinoma with ulcerative colitis resembling colitis cystica profunda].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1999;96(6):658-63.
1999: N Yasui; Masahiko Watanabe; Y Iwao; AA Sakaguchi; T Tahara; T Eramoto; Makio Mukai; Toshifumi Hibi; Masaki Kitajima
Laparoscopically assisted bowel resection for primary mucosa-associated lymphoid tissue lymphoma of the cecum.
Surgical laparoscopy, endoscopy & percutaneous techniques 1999;9(2):156-9.
1999: M Wakui; Shinichiro Okamoto; Akaru Ishida; H Kobayashi; Reiko Watanabe; Tomoharu Yajima; Yasushi Iwao; Tadakazu Hisamatsu; Toshifumi Hibi; Yasuo Ikeda
Prospective evaluation for upper gastrointestinal tract acute graft-versus-host disease after hematopoietic stem cell transplantation.
Bone marrow transplantation 1999;23(6):573-8.
1999: Masahiko Watanabe; M Ohgami; T Teramoto; Toshifumi Hibi; Masaki Kitajima
Laparoscopic ileocecal resection for Crohn's disease associated with intestinal stenosis and ileorectal fistula.
Surgery today 1999;29(5):446-8.
1999: Yoshimasa Yonamine; Masahiko Watanabe; Fukunori Kinjo; Toshifumi Hibi
Generation of MHC class I-restricted cytotoxic T cell lines and clones against colonic epithelial cells from ulcerative colitis.
Journal of clinical immunology 1999;19(1):77-85.
1999: S Okamoto; Masahiko Watanabe; M Yamazaki; T Yajima; T Hayashi; Hiromasa Ishii; M Mukai; T Yamada; N Watanabe; B A Jameson; Toshifumi Hibi
A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis.
European journal of immunology 1999;29(1):355-66.
1998: Masahiko Watanabe; Y Hosoda; S Okamoto; Motomi Yamazaki; N Inoue; Y Ueno; Y Iwao; Hiromasa Ishii; N Watanabe; Y Hamada; T Yamada; T Suzuki; Toshifumi Hibi
CD45RChighCD4+ intestinal mucosal lymphocytes infiltrating in the inflamed colonic mucosa of a novel rat colitis model induced by TNB immunization.
Clinical immunology and immunopathology 1998;88(1):46-55.
1998: T Yajima; H Takaishi; Takanori Kanai; Yasushi Iwao; Mamoru Watanabe; Hiromasa Ishii; Toshifumi Hibi
Predictive factors of response to leukocytapheresis therapy for ulcerative colitis.
Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis 1998;2(2):115-9.
1998: Hidekazu Suzuki; Masayuki Suzuki; Mikiji Mori; Tetsuji Kitahora; Hirokazu Yokoyama; Soichiro Miura; Toshifumi Hibi; Hiromasa Ishii
Augmented levels of gastric mucosal leucocyte activation by infection with cagA gene-positive Helicobacter pylori.
Journal of gastroenterology and hepatology 1998;13(3):294-300.
1998: Masahiko Watanabe; Y Ueno; Tomoharu Yajima; Susumu Okamoto; T Hayashi; Motomi Yamazaki; Yasushi Iwao; Hiromasa Ishii; S Habu; Masahiro Uehira; H Nishimoto; Hiromichi Ishikawa; J Hata; Toshifumi Hibi
Interleukin 7 transgenic mice develop chronic colitis with decreased interleukin 7 protein accumulation in the colonic mucosa.
The Journal of experimental medicine 1998;187(3):389-402.
1998: Xiaoyun Lu; S Yamamoto; M Tanaka; Toshifumi Hibi; Shigetou Namba
The genome organization of the broad bean necrosis virus (BBNV).
Archives of virology 1998;143(7):1335-48.
1997: K Yokoyama; T Amamiya; Y Kawai; Toshifumi Hibi; T Yajima; R Tanosaki; Nobuyuki Takayama; T Yamada; J Hata; Yasuo Ikeda
Acute lymphocytic leukemia associated with severe myelofibrosis.
The Keio journal of medicine 1997;46(4):196-204.
1997: K Kobayashi; Yoshiki Hamada; Hiroshi Serizawa; Noriaki Watanabe; H Takaishi; N Iwabuchi; Naoki Kumagai; Kanji Tsuchimoto; Y Yamada; S Miura; Toshifumi Hibi; Hiromasa Ishii; S Kuramochi
[A case report of ulcerative colitis complicated with protein losing enteropathy and colon cancer in a young female].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1997;94(11):772-7.
1997: K Toda; Naoki Kumagai; N Iwabuchi; T Suzuki; Hidetsugu Saito; Toshio Morizane; Toshifumi Hibi; Hiromasa Ishii; Kanji Tsuchimoto
[2-5 AS activity in serum and peripheral blood mononuclear cells for chronic active hepatitis C and the relationship to clinical outcome of interferon therapy].
Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology 1997;20(5):428-36.
1997: Masahiko Watanabe; N Watanabe; Y Iwao; H Ogata; Takanori Kanai; Y Ueno; M Tsuchiya; Hiromasa Ishii; S Aiso; S Habu; Toshifumi Hibi
The serum factor from patients with ulcerative colitis that induces T cell proliferation in the mouse thymus is interleukin-7.
Journal of clinical immunology 1997;17(4):282-92.
1996: N Inoue; Tadakazu Hisamatsu; Yasushi Iwao; M Watanabe; Hiromasa Ishii; Y Mizuno; Toshifumi Hibi
[Immunoglobulin heavy chain variable region(VH) genes in B cell clones producing anti-colon antibodies in ulcerative colitis].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(4):1176-81.
1996: M Watanabe; A Hayashi; Y Hosoda; M Ohara; Yasushi Iwao; Hiromasa Ishii; H Ishikawa; M Nanno; Toshifumi Hibi
Preferential activation of CD4+V beta 5.2/5.3+ intestinal intraepithelial lymphocytes in the inflamed lesions of Crohn's disease.
Clinical immunology and immunopathology 1996;78(2):130-9.
1995: Toshifumi Hibi; Yasushi Iwao; Tomoharu Yajima; N Inoue; Y Ueno; H Takaishi; M Watanabe; Hiromasa Ishii
Immunosuppressive agents in the treatment of Crohn's disease and ulcerative colitis.
Journal of gastroenterology 1995;30 Suppl 8():121-3.
1995: M Watanabe; Y Ueno; T Yajima; Y Iwao; M Tsuchiya; H Ishikawa; S Aiso; Toshifumi Hibi; Hiromasa Ishii
Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.
The Journal of clinical investigation 1995;95(6):2945-53.
1995: M Ohara; Toshifumi Hibi; N Watanabe; K Kobayashi; H Takaishi; A Hayashi; Y Hosoda; K Toda; Yasushi Iwao; M Watanabe
Immunoglobulin G subclass distribution of human anticolon antibodies in ulcerative colitis.
Journal of gastroenterology and hepatology 1995;10(2):158-64.
1994: H Suzuki; Toshifumi Hibi; M Oda; Y Hosoda; Mikiji Mori; Soichiro Miura; Shigeru Tanaka; M Watanabe; M Tsuchiya
Sulfhydryl blocker-induced colitis in the rat: immunological changes in thymus gland and colonic mucosa.
Journal of gastroenterology and hepatology 1994;9(6):544-50.
1994: M Sakamoto; H Serizawa; Toshifumi Hibi; Y Tsuzuki; N Hamamatsu; Soichiro Miura; Hiromasa Ishii; Masaki Kitajima; C Torikata; M Tsuchiya
[Two cases of metastasis of unknown origin syndrome: confirmed gallbladder origin by autopsy].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1994;91(4):938-43.
1994: Toshifumi Hibi; M Ohara; K Kobayashi; W R Brown; K Toda; H Takaishi; Y Hosoda; A Hayashi; Yasushi Iwao; M Watanabe
Enzyme linked immunosorbent assay (ELISA) and immunoprecipitation studies on anti-goblet cell antibody using a mucin producing cell line in patients with inflammatory bowel disease.
Gut 1994;35(2):224-30.
1993: Toshifumi Hibi; M Ohara; M Watanabe; Takanori Kanai; H Takaishi; A Hayashi; Y Hosoda; H Ogata; Yasushi Iwao; S Aiso
Interleukin 2 and interferon-gamma augment anticolon antibody dependent cellular cytotoxicity in ulcerative colitis.
Gut 1993;34(6):788-93.
1993: H Serizawa; Soichiro Miura; H Tashiro; H Imaeda; H Shiozaki; Shigeru Tanaka; M Yoshioka; M Ohara; Toshifumi Hibi; A Yamashita
Significant changes in intestinal lymphatic system and immune response elicited by Peyer's patch excision in adult rats.
Journal of gastroenterology and hepatology 1993;8(1):63-9.
1992: A Hara; Toshifumi Hibi; M Yoshioka; K Toda; N Watanabe; M Morita; T Suzuki; H Serizawa; H Saito; Yasushi Iwao
[Effect of serum factors on the differentiation of a colon cancer cell line Caco-2].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1992;89(3):588-95.
1992: Yasushi Iwao; Toshifumi Hibi; M Watanabe; H Takaishi; Y Hosoda; A Hayashi; M Ohara; H Ogata; S Aiso; K Toda
The mechanism of action of serum immunosuppressive factor in Crohn's disease: it blocks the growth of mitogen-stimulated lymphocytes in early G1 phase through an inhibition of transferrin receptor expression.
Journal of clinical & laboratory immunology 1992;38(1):15-27.
1990: Toshifumi Hibi; M Ohara; K Toda; A Hara; H Ogata; Yasushi Iwao; N Watanabe; M Watanabe; Y Hamada; K Kobayashi
In vitro anticolon antibody production by mucosal or peripheral blood lymphocytes from patients with ulcerative colitis.
Gut 1990;31(12):1371-6.
1990: Y Tsuzuki; H Serizawa; Soichiro Miura; I Kurose; Makoto Suematsu; Toshifumi Hibi; Hiromasa Ishii; Y Tashiro; S Kodaira; M Tsuchiya
[A case of Crohn's colitis with cecal perforation and abnormalities of coagulation and fibrinolytic system].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1990;87(9):1878-82.
1990: H Serizawa; Toshifumi Hibi; H Niwa; H Tashiro; Takanori Kanai; Soichiro Miura; Y Sugino; Y Tashiro; M Tsuchiya
[A case of enterocolitis with diffuse multiple aphthoid lesions in which non-caseous granulomas were demonstrated microscopically].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1990;87(8):1701-5.
1989: T Sugi; T Hashimoto; Toshifumi Hibi; Takeji Nishikawa
Production of human monoclonal anti-basement membrane zone (BMZ) antibodies from a patient with bullous pemphigoid (BP) by Epstein-Barr virus transformation. Analyses of the heterogeneity of anti-BMZ antibodies in BP sera using them.
The Journal of clinical investigation 1989;84(4):1050-5.
1989: M Watanabe; Toshifumi Hibi; Yasushi Iwao; Takanori Kanai; M Ohara; T Fujisawa; H Ogata; N Watanabe; H Asakura; S Aiso
Release of the serum immunosuppressive factor by monocytes in patients with Crohn's disease.
Journal of clinical & laboratory immunology 1989;29(4):161-6.
1989: Soichiro Miura; H Serizawa; Y Hamada; Shigeru Tanaka; M Yoshioka; Toshifumi Hibi; M Tsuchiya
Alterations of intestinal lymphatic system and mucosal immunity in CCl4-induced portal hypertensive rats.
Journal of gastroenterology and hepatology 1989;4 Suppl 1():71-4.
1988: K Kobayashi; H Asakura; Y Hamada; Toshifumi Hibi; M Watanabe; T Yoshida; N Watanabe; Soichiro Miura; S Aiso; M Tsuchiya
T lymphocyte subpopulations and immunoglobulin-containing cells in the colonic mucosa of ulcerative colitis; a morphometric and immunohistochemical study.
Journal of clinical & laboratory immunology 1988;25(2):63-8.
1987: Makoto Suematsu; Masayuki Suzuki; T Kitahora; Soichiro Miura; K Suzuki; Toshifumi Hibi; M Watanabe; H Nagata; H Asakura; M Tsuchiya
Increased respiratory burst of leukocytes in inflammatory bowel diseases--the analysis of free radical generation by using chemiluminescence probe.
Journal of clinical & laboratory immunology 1987;24(3):125-8.