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Jarmo Hietala

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Chemicals & Drugs

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Schizophrenia

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TOP 3
Antonietta Pepe; Ulla Ruotsalainen; Jarmo Hietala; Juha Koikkalainen; Lu Zhao; Jussi Tohka
Automatic statistical shape analysis of cerebral asymmetry in 3D T1-weighted magnetic resonance images at vertex-level: Application to neuroleptic-naïve schizophrenia.
Linnea Karlsson; Sami Leppämäki; Elina Sihvola; Maria Sipilä; Pekka Tani; Lauri Tuominen; Semi Helin; Jarmo Hietala; Jussi Hirvonen; Antti Huotarinen; Hasse Karlsson
Serotonin transporter in attention-deficit hyperactivity disorder - preliminary results from a positron emission tomography study.
L Tuominen; J Viikari; C R Cloninger; Jarmo Hietala; Jussi Hirvonen; E Isometsä; P Laine; T Melartin; Kjell Någren; O Raitakari; J Salo; L Keltikangas-Järvinen
Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort.

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All Publications

2013: Antonietta Pepe; Ulla Ruotsalainen; Jarmo Hietala; Juha Koikkalainen; Lu Zhao; Jussi Tohka
Automatic statistical shape analysis of cerebral asymmetry in 3D T1-weighted magnetic resonance images at vertex-level: Application to neuroleptic-naïve schizophrenia.
Magnetic resonance imaging 2013;31(5):676-87.
2013: Linnea Karlsson; Sami Leppämäki; Elina Sihvola; Maria Sipilä; Pekka Tani; Lauri Tuominen; Semi Helin; Jarmo Hietala; Jussi Hirvonen; Antti Huotarinen; Hasse Karlsson
Serotonin transporter in attention-deficit hyperactivity disorder - preliminary results from a positron emission tomography study.
Psychiatry research 2013;212(2):164-5.
2013: L Tuominen; J Viikari; C R Cloninger; Jarmo Hietala; Jussi Hirvonen; E Isometsä; P Laine; T Melartin; Kjell Någren; O Raitakari; J Salo; L Keltikangas-Järvinen
Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort.
Psychological medicine 2013;43(4):881-94.
2012: Nora Hagelberg; Jarmo Hietala; Sargo Aalto; Kjell Någren; Antti Pertovaara; Ullamari Pesonen; Harry Scheinin; Lauri Tuominen; Ilkka K Martikainen
Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects.
Neuroscience letters 2012;521(1):11-4.
2012: Lauri Tuominen; Jorma Viikari; Jussi Hirvonen; Erkki Isometsä; Liisa Keltikangas-Järvinen; Pauliina Laine; Tarja Melartin; Kjell Någren; Olli Raitakari; Johanna Salo; Jarmo Hietala
Temperament trait Harm Avoidance associates with μ-opioid receptor availability in frontal cortex: a PET study using [(11)C]carfentanil.
NeuroImage 2012;61(3):670-6.
2011: Jussi Hirvonen; Jaana Kajander; Sargo Aalto; Jarmo Hietala; Juha Markkula; Kjell Någren; Helena Rasi-Hakala; Jouko K Salminen; Hasse Karlsson
Effects of antidepressant drug treatment and psychotherapy on striatal and thalamic dopamine D2/3 receptors in major depressive disorder studied with [11C]raclopride PET.
Journal of psychopharmacology (Oxford, England) 2011;25(10):1329-36.
2011: Kim Kronström; Jouko K Salminen; Jarmo Hietala; Jaana Kajander; Tero Vahlberg; Juha Markkula; Helena Rasi-Hakala; Hasse Karlsson
Personality traits and recovery from major depressive disorder.
Nordic journal of psychiatry 2011;65(1):52-7.
2010: Lu Zhao; Ulla Ruotsalainen; Jussi Hirvonen; Jarmo Hietala; Jussi Tohka
Automatic cerebral and cerebellar hemisphere segmentation in 3D MRI: adaptive disconnection algorithm.
Medical image analysis 2010;14(3):360-72.
2010: Ville Lumme; Mika M Hirvonen; Tuula Ilonen; Jussi Hirvonen; Kjell Någren; Jarmo Hietala
Cortical dopamine D2/D3 receptors and verbal memory in man.
NeuroImage 2010;51(2):918-22.
2010: Mika M Hirvonen; Kjell Någren; Juha O Rinne; Ullamari Pesonen; Tero Vahlberg; Nora Hagelberg; Jarmo Hietala
COMT Val158Met genotype does not alter cortical or striatal dopamine D2 receptor availability in vivo.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(2):192-7.
2010: Hasse Karlsson; Jussi Hirvonen; Jaana Kajander; Juha Markkula; H Rasi-Hakala; Jouko K Salminen; Kjell Någren; Sargo Aalto; Jarmo Hietala
Research letter: Psychotherapy increases brain serotonin 5-HT1A receptors in patients with major depressive disorder.
Psychological medicine 2010;40(3):523-8.
2009: Harry Vilkman; Jaana Kajander; Sargo Aalto; Tero Vahlberg; Kjell Någren; Topias Allonen; Erkka Syvälahti; Jarmo Hietala
The effects of lorazepam on extrastriatal dopamine D(2/3)-receptors-A double-blind randomized placebo-controlled PET study.
Psychiatry research 2009;174(2):130-7.
2009: Mika M Hirvonen; Aki Laakso; Kjell Någren; Juha O Rinne; Tiina Pohjalainen; Jarmo Hietala
C957T polymorphism of dopamine D2 receptor gene affects striatal DRD2 in vivo availability by changing the receptor affinity.
Synapse (New York, N.Y.) 2009;63(10):907-12.
2009: Ilkka K Martikainen; Jussi Hirvonen; Ullamari Pesonen; Nora Hagelberg; Heikki Laurikainen; Heikki Tuikkala; Jaana Kajander; Kjell Någren; Jarmo Hietala; Antti Pertovaara
Differential associations between brain 5-HT(1A) receptor binding and response to pain versus touch.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(7):821-30.
2009: Mika M Hirvonen; Ville Lumme; Jussi Hirvonen; Ullamari Pesonen; Kjell Någren; Tero Vahlberg; Harry Scheinin; Jarmo Hietala
C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo.
Progress in neuro-psychopharmacology & biological psychiatry 2009;33(4):630-6.
2009: Raimo K R Salokangas; Markus Heinimaa; Tanja Svirskis; Tiina Laine; Jukka Huttunen; Terja Ristkari; Tuula Ilonen; Jyrki Korkeila; Leena Vaskelainen; Jaakko Rekola; Jarmo Hietala; Joachim Klosterkötter; Stephan Ruhrmann; Heinrich Graf von Reventlow; Don Linszen; Peter Dingemans; Max Birchwood; Paul Patterson
Perceived negative attitude of others as an early sign of psychosis.
European psychiatry : the journal of the Association of European Psychiatrists 2009;24(4):233-8.
2009: Sargo Aalto; Jussi Hirvonen; Valtteri Kaasinen; Nora Hagelberg; Jaana Kajander; Kjell Någren; Timo Seppälä; Juha O Rinne; Harry Scheinin; Jarmo Hietala
The effects of d-amphetamine on extrastriatal dopamine D2/D3 receptors: a randomized, double-blind, placebo-controlled PET study with [11C]FLB 457 in healthy subjects.
European journal of nuclear medicine and molecular imaging 2009;36(3):475-83.
2009: Lu Zhao; Jarmo Hietala; Jussi Tohka
Shape analysis of human brain interhemispheric fissure bending in MRI.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 2009;12(Pt 2):216-23.
2009: Ricardo J P C Farinha; Ulla Ruotsalainen; Jussi Hirvonen; Lauri Tuominen; Jarmo Hietala; José M Fonseca; Jussi Tohka
Segmentation of striatal brain structures from high resolution PET images.
International journal of biomedical imaging 2009;2009():156234.
2009: Kim Kronström; Jouko K Salminen; Jarmo Hietala; Jaana Kajander; Tero Vahlberg; Juha Markkula; Helena Rasi-Hakala; Hasse Karlsson
Does defense style or psychological mindedness predict treatement response in major depression?
Depression and anxiety 2009;26(7):689-95.
2008: Veronica Fagerholm; Johanna Rokka; Leena Nyman; Jukka Sallinen; Jari Tiihonen; Erkki Tupala; Merja Haaparanta; Jarmo Hietala
Autoradiographic characterization of alpha(2C)-adrenoceptors in the human striatum.
Synapse (New York, N.Y.) 2008;62(7):508-15.
2008: Jussi Hirvonen; Hasse Karlsson; Jaana Kajander; Antti Lepola; Juha Markkula; Helena Rasi-Hakala; Kjell Någren; Jouko K Salminen; Jarmo Hietala
Decreased brain serotonin 5-HT1A receptor availability in medication-naive patients with major depressive disorder: an in-vivo imaging study using PET and [carbonyl-11C]WAY-100635.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2008;11(4):465-76.
2008: Jussi Hirvonen; Hasse Karlsson; Jaana Kajander; Juha Markkula; Helena Rasi-Hakala; Kjell Någren; Jouko K Salminen; Jarmo Hietala
Striatal dopamine D2 receptors in medication-naive patients with major depressive disorder as assessed with [11C]raclopride PET.
Psychopharmacology 2008;197(4):581-90.
2008: Jussi Hirvonen; Jarkko Johansson; Mika Teräs; Vesa Oikonen; Ville Lumme; Pauliina Virsu; Anne Roivainen; Kjell Någren; Christer Halldin; Lars Farde; Jarmo Hietala
Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(5):1059-69.
2008: Jouko K Salminen; Hasse Karlsson; Jarmo Hietala; Jaana Kajander; Sargo Aalto; Juha Markkula; Helena Rasi-Hakala; Tuula Toikka
Short-term psychodynamic psychotherapy and fluoxetine in major depressive disorder: a randomized comparative study.
Psychotherapy and psychosomatics 2008;77(6):351-7.
2008: Esa Wallius; Jussi Tohka; Jussi Hirvonen; Jarmo Hietala; Ulla Ruotsalainen
Evaluation of the automatic three-dimensional delineation of caudate and putamen for PET receptor occupancy studies.
Nuclear medicine communications 2008;29(1):53-65.
2008: Jukka Huttunen; Markus Heinimaa; Tanja Svirskis; Mikko Nyman; Jaana Kajander; Sarita Forsback; Olof Solin; Tuula Ilonen; Jyrki Korkeila; Terja Ristkari; Thomas H McGlashan; Raimo K R Salokangas; Jarmo Hietala
Striatal dopamine synthesis in first-degree relatives of patients with schizophrenia.
Biological psychiatry 2008;63(1):114-7.
2007: Ville Lumme; Sargo Aalto; Tuula Ilonen; Kjell Någren; Jarmo Hietala
Dopamine D2/D3 receptor binding in the anterior cingulate cortex and executive functioning.
Psychiatry research 2007;156(1):69-74.
2007: Ilkka K Martikainen; Jussi Hirvonen; Jaana Kajander; Nora Hagelberg; Heikki Mansikka; Kjell Någren; Jarmo Hietala; Antti Pertovaara
Correlation of human cold pressor pain responses with 5-HT(1A) receptor binding in the brain.
Brain research 2007;1172():21-31.
2007: Esa Wallius; Mikko Nyman; Vesa Oikonen; Jarmo Hietala; Ulla Ruotsalainen
Voxel-based NK1 receptor occupancy measurements with [(18)F]SPA-RQ and positron emission tomography: a procedure for assessing errors from image reconstruction and physiological modeling.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2007;9(5):284-94.
2007: Raimo K R Salokangas; Teija Honkonen; Eija Stengård; Jarmo Hietala
Body mass index and functioning in long-term schizophrenia. Results of the DSP project.
European psychiatry : the journal of the Association of European Psychiatrists 2007;22(5):313-8.
2007: Mikko J Nyman; Olli Eskola; Jaana Kajander; Tero Vahlberg; Sandra Sanabria; Donald Burns; Richard Hargreaves; Olof Solin; Jarmo Hietala
Gender and age affect NK1 receptors in the human brain - a positron emission tomography study with [18F]SPA-RQ.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2007;10(2):219-29.
2007: Tanja Svirskis; Jyrki Korkeila; Markus Heinimaa; Jukka Huttunen; Tuula Ilonen; Terja Ristkari; Jarmo Hietala; Erkka Syvälahti; Thomas H McGlashan; Tero Vahlberg; Raimo K R Salokangas
Quality of life and functioning ability in subjects vulnerable to psychosis.
Comprehensive psychiatry 2007;48(2):155-60.
2007: Jussi Hirvonen; Jaana Kajander; Topias Allonen; Vesa Oikonen; Kjell Någren; Jarmo Hietala
Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-(11)C]WAY-100635-considerations on the validity of cerebellum as a reference region.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):185-95.
2006: Jussi Hirvonen; Theo G M van Erp; Jukka Huttunen; Sargo Aalto; Kjell Någren; Matti O Huttunen; Jouko Lönnqvist; Jaakko Kaprio; Tyrone D Cannon; Jarmo Hietala
Brain dopamine d1 receptors in twins discordant for schizophrenia.
The American journal of psychiatry 2006;163(10):1747-53.
2006: Raimo K R Salokangas; Teija Honkonen; Eija Stengård; Anna-Maija Koivisto; Jarmo Hietala
Cigarette smoking in long-term schizophrenia.
European psychiatry : the journal of the Association of European Psychiatrists 2006;21(4):219-23.
2006: Martin Keller; Stuart Montgomery; William Ball; Mary Morrison; Duane Snavely; Guanghan Liu; Richard Hargreaves; Jarmo Hietala; Christopher R Lines; Katherine Beebe; Scott A Reines
Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder.
Biological psychiatry 2006;59(3):216-23.
2006: Jussi Hirvonen; Theo G M van Erp; Jukka Huttunen; Kjell Någren; Matti O Huttunen; Sargo Aalto; Jouko Lönnqvist; Jaakko Kaprio; Tyrone D Cannon; Jarmo Hietala
Striatal dopamine D1 and D2 receptor balance in twins at increased genetic risk for schizophrenia.
Psychiatry research 2006;146(1):13-20.
2006: Erkka Syvälahti; Jani Penttilä; Hannu Majasuo; Esa-Pekka Pälvimäki; Aki Laakso; Jarmo Hietala
Combined treatment with citalopram and buspirone: effects on serotonin 5-HT2A and 5-HT2C receptors in the rat brain.
Pharmacopsychiatry 2006;39(1):1-8.
2005: Kimmo Ingman; Nora Hagelberg; Sargo Aalto; Kjell Någren; Auni Juhakoski; Sakari Karhuvaara; Antero Kallio; Vesa Oikonen; Jarmo Hietala; Harry Scheinin
Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(12):2245-53.
2005: Sargo Aalto; Jouni A Ihalainen; Jussi Hirvonen; Jaana Kajander; Harry Scheinin; Heikki Tanila; Kjell Någren; Harry Vilkman; Lars ´Gustafsson; Erkka Syvälahti; Jarmo Hietala
Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man.
Psychopharmacology 2005;182(3):375-83.
2005: Jani Penttilä; Jarmo Hietala
Proposed mechanisms of action of SSRIs.
Journal of the American Academy of Child and Adolescent Psychiatry 2005;44(10):968; discussion 969.
2005: Jarmo Hietala; Mikko J Nyman; Olli Eskola; Aki Laakso; Tove Grönroos; Vesa Oikonen; Jörgen Bergman; Merja Haaparanta; Sarita Forsback; Päivi Marjamäki; Pertti Lehikoinen; Michael Goldberg; Donald Burns; Terence G Hamill; Waisi Eng; Alexandre Coimbra; Richard Hargreaves; Olof Solin
Visualization and quantification of neurokinin-1 (NK1) receptors in the human brain.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(4):262-72.
2005: Aki Laakso; Tiina Pohjalainen; Jörgen Bergman; Jaana Kajander; Merja Haaparanta; Olof Solin; Erkka Syvälahti; Jarmo Hietala
The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.
Pharmacogenetics and genomics 2005;15(6):387-91.
2005: Esa-Pekka Pälvimäki; Hannu Majasuo; Erkka Syvälahti; Jarmo Hietala
Serotonin 5-HT2C receptor-mediated phosphoinositide hydrolysis in rat choroid plexus after fluoxetine and citalopram treatments.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;51(5):419-25.
2005: Jussi Hirvonen; Theo G M van Erp; Jukka Huttunen; Sargo Aalto; Kjell Någren; Matti O Huttunen; Jouko Lönnqvist; Jaakko Kaprio; Jarmo Hietala; Tyrone D Cannon
Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia.
Archives of general psychiatry 2005;62(4):371-8.
2005: Ilkka K Martikainen; Nora Hagelberg; Heikki Mansikka; Jarmo Hietala; Kjell Någren; Harry Scheinin; Antti Pertovaara
Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia.
Neuroscience letters 2005;376(3):149-53.
2004: Jani Penttilä; Jaana Kajander; Sargo Aalto; Jussi Hirvonen; Kjell Någren; Tuula Ilonen; Erkka Syvälahti; Jarmo Hietala
Effects of fluoxetine on dopamine D2 receptors in the human brain: a positron emission tomography study with [11C]raclopride.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(4):431-9.
2004: M Hirvonen; Aki Laakso; Kjell Någren; Juha O Rinne; Tiina Pohjalainen; Jarmo Hietala
C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo.
Molecular psychiatry 2004;9(12):1060-1.
2004: Olof Solin; Olli Eskola; Terence G Hamill; Jörgen Bergman; Pertti Lehikoinen; Tove Grönroos; Sarita Forsback; Merja Haaparanta; Tapio Viljanen; Christine Ryan; Raymond Gibson; Gerard Kieczykowski; Jarmo Hietala; Richard Hargreaves; H Donald Burns
Synthesis and characterization of a potent, selective, radiolabeled substance-P antagonist for NK1 receptor quantitation: ([18F]SPA-RQ).
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(6):373-84.
2004: Nora Hagelberg; Satu Jääskeläinen; Ilkka K Martikainen; Heikki Mansikka; Heli Forssell; Harry Scheinin; Jarmo Hietala; Antti Pertovaara
Striatal dopamine D2 receptors in modulation of pain in humans: a review.
European journal of pharmacology 2004;500(1-3):187-92.
2004: Antti Pertovaara; Ilkka K Martikainen; Nora Hagelberg; Heikki Mansikka; Kjell Någren; Jarmo Hietala; Harry Scheinin
Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain.
The European journal of neuroscience 2004;20(6):1587-92.
2004: Mats Bergström; Richard Hargreaves; H Donald Burns; Michael R Goldberg; David Sciberras; Scott A Reines; Petty Kevin; Mats Ogren; Gunnar Antoni; Bengt Långström; Olli Eskola; Mika Scheinin; Olof Solin; Anup K Majumdar; Marvin Constanzer; Wendy P Battisti; Thomas E Bradstreet; Cynthia Gargano; Jarmo Hietala
Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant.
Biological psychiatry 2004;55(10):1007-12.
2004: Nora Hagelberg; Sargo Aalto; Jaana Kajander; Vesa Oikonen; Susanna Hinkka; Kjell Någren; Jarmo Hietala; Harry Scheinin
Alfentanil increases cortical dopamine D2/D3 receptor binding in healthy subjects.
Pain 2004;109(1-2):86-93.
2004: Jari Tiihonen; Anna Keski-Rahkonen; Mari Löppönen; Maria Muhonen; Jaana Kajander; Topias Allonen; Kjell Någren; Jarmo Hietala; Aila Rissanen
Brain serotonin 1A receptor binding in bulimia nervosa.
Biological psychiatry 2004;55(8):871-3.
2004: Taina Nieminen-von Wendt; Liisa Metsähonkala; Tuula Kulomäki; Sargo Aalto; Taina Autti; Raija Vanhala; Olli Eskola; Jörgen Bergman; Jarmo Hietala; Lennart von Wendt
Increased presynaptic dopamine function in Asperger syndrome.
Neuroreport 2004;15(5):757-60.
2004: Jarmo Hietala
[Schizophrenia as a consequence of genetic modifications affecting brain development and plasticity].
Duodecim; lääketieteellinen aikakauskirja 2004;120(14):1715-6.
2003: Christian C Joyal; Mikko P Laakso; Jari Tiihonen; Erkka Syvälahti; Harry Vilkman; Aki Laakso; Birgitta Alakare; Viljo Räkköläinen; Raimo K R Salokangas; Jarmo Hietala
The amygdala and schizophrenia: a volumetric magnetic resonance imaging study in first-episode, neuroleptic-naive patients.
Biological psychiatry 2003;54(11):1302-4.
2003: Jussi Hirvonen; Sargo Aalto; V Lumme; Kjell Någren; Jaana Kajander; Harry Vilkman; Nora Hagelberg; Vesa Oikonen; Jarmo Hietala
Measurement of striatal and thalamic dopamine D2 receptor binding with 11C-raclopride.
Nuclear medicine communications 2003;24(12):1207-14.
2003: Jarmo Hietala; Tyrone D Cannon; Theo G M van Erp; Erkka Syvälahti; Harry Vilkman; Aki Laakso; Tero Vahlberg; Birgitta Alakare; Viljo Räkköläinen; Raimo K R Salokangas
Regional brain morphology and duration of illness in never-medicated first-episode patients with schizophrenia.
Schizophrenia research 2003;64(1):79-81.
2003: Tero Hallikainen; Jarmo Hietala; Jussi Kauhanen; Tiina Pohjalainen; Erkka Syvälahti; Jukka T Salonen; Jari Tiihonen
Ethanol consumption and DRD2 gene TaqI a polymorphism among socially drinking males.
American journal of medical genetics. Part A 2003;119A(2):152-5.
2003: Aki Laakso; Esa Wallius; Jaana Kajander; Jörgen Bergman; Olli Eskola; Olof Solin; Tuula Ilonen; Raimo K R Salokangas; Erkka Syvälahti; Jarmo Hietala
Personality traits and striatal dopamine synthesis capacity in healthy subjects.
The American journal of psychiatry 2003;160(5):904-10.
2003: Raimo K R Salokangas; Teija Honkonen; Eija Stengård; Anna-Maija Koivisto; Jarmo Hietala
Negative symptoms and neuroleptics in catatonic schizophrenia.
Schizophrenia research 2003;59(1):73-6.
2002: Sargo Aalto; Jussi Hirvonen; Jaana Kajander; Harry Scheinin; Kjell Någren; Harry Vilkman; Lars ´Gustafsson; Erkka Syvälahti; Jarmo Hietala
Ketamine does not decrease striatal dopamine D2 receptor binding in man.
Psychopharmacology 2002;164(4):401-6.
2002: Aki Laakso; Harry Vilkman; Jörgen Bergman; Merja Haaparanta; Olof Solin; Erkka Syvälahti; Raimo K R Salokangas; Jarmo Hietala
Sex differences in striatal presynaptic dopamine synthesis capacity in healthy subjects.
Biological psychiatry 2002;52(7):759-63.
2002: Raimo K R Salokangas; Tyrone Cannon; Theo G M van Erp; Tuula Ilonen; Tero Taiminen; Hasse Karlsson; Hannu Lauerma; Kirsi-Marja Leinonen; Elina Wallenius; Anne Kaljonen; Erkka Syvälahti; Harry Vilkman; Anna Alanen; Jarmo Hietala
Structural magnetic resonance imaging in patients with first-episode schizophrenia, psychotic and severe non-psychotic depression and healthy controls. Results of the schizophrenia and affective psychoses (SAP) project.
The British journal of psychiatry. Supplement 2002;43():s58-65.
2002: Nora Hagelberg; Ilkka K Martikainen; Heikki Mansikka; Susanna Hinkka; Kjell Någren; Jarmo Hietala; Harry Scheinin; Antti Pertovaara
Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity.
Pain 2002;99(1-2):273-9.
2002: Nora Hagelberg; Jaana Kajander; Kjell Någren; Susanna Hinkka; Jarmo Hietala; Harry Scheinin
Mu-receptor agonism with alfentanil increases striatal dopamine D2 receptor binding in man.
Synapse (New York, N.Y.) 2002;45(1):25-30.
2002: Christian C Joyal; Mikko P Laakso; Jari Tiihonen; Erkka Syvälahti; Harry Vilkman; Aki Laakso; Birgitta Alakare; Viljo Räkköläinen; Raimo K R Salokangas; Jarmo Hietala
A volumetric MRI study of the entorhinal cortex in first episode neuroleptic-naive schizophrenia.
Biological psychiatry 2002;51(12):1005-7.
2002: Takuya Saito; Herbert M Lachman; Libna Diaz; Tero Hallikainen; Jussi Kauhanen; Jukka T Salonen; Olli-Pekka Ryynänen; Matti K Karvonen; Erkka Syvälahti; Tiina Pohjalainen; Jarmo Hietala; Jari Tiihonen
Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics.
Psychiatry research 2002;109(2):113-9.
2001: Jussi Hirvonen; Kjell Någren; Jaana Kajander; Jarmo Hietala
Measurement of cortical dopamine d1 receptor binding with 11C[SCH23390]: a test-retest analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(10):1146-50.
2001: Aki Laakso; Jörgen Bergman; Merja Haaparanta; Harry Vilkman; Olof Solin; Erkka Syvälahti; Jarmo Hietala
Decreased striatal dopamine transporter binding in vivo in chronic schizophrenia.
Schizophrenia research 2001;52(1-2):115-20.
2001: Jarmo Hietala; M Kuonnamäki; Esa-Pekka Pälvimäki; Aki Laakso; Hannu Majasuo; Erkka Syvälahti
Sertindole is a serotonin 5-HT2c inverse agonist and decreases agonist but not antagonist binding to 5-HT2c receptors after chronic treatment.
Psychopharmacology 2001;157(2):180-7.
2001: Mikko P Laakso; Jari Tiihonen; Erkka Syvälahti; Harry Vilkman; Aki Laakso; Birgitta Alakare; Viljo Räkköläinen; Raimo K R Salokangas; E Koivisto; Jarmo Hietala
A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naïve schizophrenia.
Schizophrenia research 2001;50(1-2):3-7.
2001: TP Laine; Aapo Ahonen; Pirkko Räsänen; Tiina Pohjalainen; Jari Tiihonen; Jarmo Hietala
The A1 allele of the D2 dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics.
Alcohol and alcoholism (Oxford, Oxfordshire) 2001;36(3):262-5.
2001: Valtteri Kaasinen; Kjell Någren; Jarmo Hietala; Lars Farde; Juha O Rinne
Sex differences in extrastriatal dopamine d(2)-like receptors in the human brain.
The American journal of psychiatry 2001;158(2):308-11.
2000: Harry Vilkman; Jaana Kajander; Kjell Någren; Vesa Oikonen; Erkka Syvälahti; Jarmo Hietala
Measurement of extrastriatal D2-like receptor binding with [11C]FLB 457--a test-retest analysis.
European journal of nuclear medicine 2000;27(11):1666-73.
2000: Aki Laakso; Jarmo Hietala
PET studies of brain monoamine transporters.
Current pharmaceutical design 2000;6(16):1611-23.
2000: Valtteri Kaasinen; Harry Vilkman; Jarmo Hietala; Kjell Någren; Hans Helenius; H Olsson; Lars Farde; J Rinne
Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain.
Neurobiology of aging 2000;21(5):683-8.
2000: Vesa Oikonen; Topias Allonen; Kjell Någren; Jaana Kajander; Jarmo Hietala
Quantification of [Carbonyl-(11)C]WAY-100635 binding: considerations on the cerebellum.
Nuclear medicine and biology 2000;27(5):483-6.
2000: Erkka Syvälahti; Viljo Räkköläinen; Jukka Aaltonen; Ville Lehtinen; Jarmo Hietala
Striatal D(2) dopamine receptor density and psychotic symptoms in schizophrenia: a longitudinal study.
Schizophrenia research 2000;43(2-3):159-61.
2000: Tero Hallikainen; Herbert M Lachman; T Saito; Jan Volavka; Jussi Kauhanen; Jukka T Salonen; Olli-Pekka Ryynänen; Markku Koulu; Matti K Karvonen; Tiina Pohjalainen; Erkka Syvälahti; Jarmo Hietala; Jari Tiihonen
Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early-onset alcoholism associated with severe antisocial behavior.
American journal of medical genetics 2000;96(3):348-52.
2000: Valtteri Kaasinen; Kjell Någren; Jarmo Hietala; Vesa Oikonen; Harry Vilkman; Lars Farde; Christer Halldin; Juha O Rinne
Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson's disease.
Neurology 2000;54(7):1482-7.
2000: Raimo K R Salokangas; Harry Vilkman; Tuula Ilonen; Tero Taiminen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Anna Alanen; Erkka Syvälahti; Jarmo Hietala
High levels of dopamine activity in the basal ganglia of cigarette smokers.
The American journal of psychiatry 2000;157(4):632-4.
2000: Aki Laakso; Harry Vilkman; Jaana Kajander; Jörgen Bergman; M paranta; Olof Solin; Jarmo Hietala
Prediction of detached personality in healthy subjects by low dopamine transporter binding.
The American journal of psychiatry 2000;157(2):290-2.
2000: Aki Laakso; Harry Vilkman; Birgitta Alakare; Merja Haaparanta; Jörgen Bergman; Olof Solin; J Peurasaari; Viljo Räkköläinen; Erkka Syvälahti; Jarmo Hietala
Striatal dopamine transporter binding in neuroleptic-naive patients with schizophrenia studied with positron emission tomography.
The American journal of psychiatry 2000;157(2):269-71.
1999: Tiina Pohjalainen; Kjell Någren; Erkka Syvälahti; Jarmo Hietala
The dopamine D2 receptor 5'-flanking variant, -141C Ins/Del, is not associated with reduced dopamine D2 receptor density in vivo.
Pharmacogenetics 1999;9(4):505-9.
1999: Tero Hallikainen; T Saito; Herbert M Lachman; Jan Volavka; Tiina Pohjalainen; Olli-Pekka Ryynänen; Jussi Kauhanen; Erkka Syvälahti; Jarmo Hietala; Jari Tiihonen
Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior.
Molecular psychiatry 1999;4(4):385-8.
1999: Hanna Kanerva; Harry Vilkman; Kjell Någren; O Kilkku; M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Brain 5-HT2A receptor occupancy of deramciclane in humans after a single oral administration--a positron emission tomography study.
Psychopharmacology 1999;145(1):76-81.
1999: Jari Tiihonen; Tero Hallikainen; Herbert M Lachman; T Saito; Jan Volavka; Jussi Kauhanen; Jukka T Salonen; Olli-Pekka Ryynänen; Markku Koulu; Matti K Karvonen; Tiina Pohjalainen; Erkka Syvälahti; Jarmo Hietala
Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism.
Molecular psychiatry 1999;4(3):286-9.
1999: Jarmo Hietala; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; Erkka Syvälahti
Measurement of striatal D2 dopamine receptor density and affinity with [11C]-raclopride in vivo: a test-retest analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(2):210-7.
1999: Jarmo Hietala; Erkka Syvälahti; Harry Vilkman; K Vuorio; Viljo Räkköläinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; M Kuoppamäki; E Eronen; Ulla Ruotsalainen; Raimo K R Salokangas
Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophrenia.
Schizophrenia research 1999;35(1):41-50.
1998: Tiina Pohjalainen; Juha O Rinne; Kjell Någren; Erkka Syvälahti; Jarmo Hietala
Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo.
The American journal of psychiatry 1998;155(6):768-73.
1998: Tiina Pohjalainen; Juha O Rinne; Kjell Någren; Pertti Lehikoinen; K Anttila; Erkka Syvälahti; Jarmo Hietala
The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers.
Molecular psychiatry 1998;3(3):256-60.
1998: Jari Tiihonen; Harry Vilkman; Pirkko Räsänen; Olli-Pekka Ryynänen; Helinä Hakko; Jörgen Bergman; T Hämäläinen; Aki Laakso; M Haaparanta-Solin; Olof Solin; M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Striatal presynaptic dopamine function in type 1 alcoholics measured with positron emission tomography.
Molecular psychiatry 1998;3(2):156-61.
1998: Esa-Pekka Pälvimäki; Hannu Majasuo; M Kuoppamäki; P T Männistö; Erkka Syvälahti; Jarmo Hietala
Deramciclane, a putative anxiolytic drug, is a serotonin 5-HT2C receptor inverse agonist but fails to induce 5-HT2C receptor down-regulation.
Psychopharmacology 1998;136(2):99-104.
1998: Aki Laakso; Jörgen Bergman; Merja Haaparanta; Harry Vilkman; Olof Solin; Jarmo Hietala
[18F]CFT [(18F)WIN 35,428], a radioligand to study the dopamine transporter with PET: characterization in human subjects.
Synapse (New York, N.Y.) 1998;28(3):244-50.
1998: Erkka Syvälahti; Jarmo Hietala
[The use of imaging techniques in drug research].
Duodecim; lääketieteellinen aikakauskirja 1998;114(10):1019-26.
1997: Jarmo Hietala; M Kuoppamäki; Kjell Någren; Pertti Lehikoinen; Erkka Syvälahti
Effects of lorazepam administration on striatal dopamine D2 receptor binding characteristics in man--a positron emission tomography study.
Psychopharmacology 1997;132(4):361-5.
1997: Tiina Pohjalainen; A Cravchik; Pablo V Gejman; J Rinne; Kjell Någren; Erkka Syvälahti; Jarmo Hietala
Antagonist binding characteristics of the Ser311-->Cys variant of human dopamine D2 receptor in vivo and in vitro.
Biochemical and biophysical research communications 1997;232(1):143-6.
1997: Jarmo Hietala; Tiina Pohjalainen; U Heikkilä-Kallio; C West; M Salaspuro; Erkka Syvälahti
Allelic association between D2 but not D1 dopamine receptor gene and alcoholism in Finland.
Psychiatric genetics 1997;7(1):19-25.
1996: G Wong; M Kuoppamäki; Jarmo Hietala; Hartmut Lüddens; Erkka Syvälahti; Esa R Korpi
Effects of clozapine metabolites and chronic clozapine treatment on rat brain GABAA receptors.
European journal of pharmacology 1996;314(3):319-23.
1996: Jari Tiihonen; M Kuoppamäki; Kjell Någren; Jörgen Bergman; E Eronen; Erkka Syvälahti; Jarmo Hietala
Serotonergic modulation of striatal D2 dopamine receptor binding in humans measured with positron emission tomography.
Psychopharmacology 1996;126(4):277-80.
1996: E P Pälvimäki; Bryan L Roth; H Majasuo; Aki Laakso; M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor.
Psychopharmacology 1996;126(3):234-40.
1996: Merja Haaparanta; Jörgen Bergman; Aki Laakso; Jarmo Hietala; Olof Solin
[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: biodistribution in rats.
Synapse (New York, N.Y.) 1996;23(4):321-7.
1996: Aki Laakso; E P Pälvimäki; M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Chronic citalopram and fluoxetine treatments upregulate 5-HT2c receptors in the rat choroid plexus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(2):143-51.
1995: Jarmo Hietala; Erkka Syvälahti; K Vuorio; V Räkköläinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; M Kuoppamäki; Olli A Kirvelä; Ulla Ruotsalainen
Presynaptic dopamine function in striatum of neuroleptic-naive schizophrenic patients.
Lancet 1995;346(8983):1130-1.
1995: M Kuoppamäki; E P Pälvimäki; Jarmo Hietala; Erkka Syvälahti
Differential regulation of rat 5-HT2A and 5-HT2C receptors after chronic treatment with clozapine, chlorpromazine and three putative atypical antipsychotic drugs.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1995;13(2):139-50.
1994: Jarmo Hietala; C West; Erkka Syvälahti; Kjell Någren; Pertti Lehikoinen; Pirkko Sonninen; Ulla Ruotsalainen
Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence.
Psychopharmacology 1994;116(3):285-90.
1994: M Kuoppamäki; T Seppälä; Erkka Syvälahti; Jarmo Hietala
Regulation of serotonin 5-HT2C receptors in the rat choroid plexus after acute clozapine treatment.
European journal of pharmacology 1994;269(2):201-8.
1994: Erkka Syvälahti; Tiina Pohjalainen; Esa R Korpi; E P Pälvimäki; T Ovaska; M Kuoppamäki; Jarmo Hietala
Dopamine D2 receptor gene expression in rat lines selected for differences in voluntary alcohol consumption.
Alcoholism, clinical and experimental research 1994;18(4):1029-31.
1994: E P Pälvimäki; Aki Laakso; M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Up-regulation of beta 1-adrenergic receptors in rat brain after chronic citalopram and fluoxetine treatments.
Psychopharmacology 1994;115(4):543-6.
1994: M Kuoppamäki; E P Pälvimäki; Erkka Syvälahti; Jarmo Hietala
5-HT1C receptor-mediated phosphoinositide hydrolysis in the rat choroid plexus after chronic treatment with clozapine.
European journal of pharmacology 1994;255(1-3):91-7.
1994: Jarmo Hietala; Erkka Syvälahti; K Vuorio; Kjell Någren; Pertti Lehikoinen; Ulla Ruotsalainen; V Räkköläinen; Ville Lehtinen; U Wegelius
Striatal D2 dopamine receptor characteristics in neuroleptic-naive schizophrenic patients studied with positron emission tomography.
Archives of general psychiatry 1994;51(2):116-23.
1993: M Kuoppamäki; Erkka Syvälahti; Jarmo Hietala
Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists.
European journal of pharmacology 1993;245(2):179-82.
1993: Juha O Rinne; Jarmo Hietala; Ulla Ruotsalainen; E Säkö; A Laihinen; Kjell Någren; Pertti Lehikoinen; Vesa Oikonen; Erkka Syvälahti
Decrease in human striatal dopamine D2 receptor density with age: a PET study with [11C]raclopride.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(2):310-4.
1993: M Kuoppamäki; T Seppälä; Erkka Syvälahti; Jarmo Hietala
Chronic clozapine treatment decreases 5-hydroxytryptamine1C receptor density in the rat choroid plexus: comparison with haloperidol.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1262-7.
1992: Jarmo Hietala; Markku Koulu; M Kuoppamäki; J Lappalainen; Erkka Syvälahti
Chronic clozapine treatment down-regulates serotonin 5-HT-1c receptors in rat brain.
Progress in neuro-psychopharmacology & biological psychiatry 1992;16(5):727-32.
1992: J Lappalainen; Jarmo Hietala; Tiina Pohjalainen; Erkka Syvälahti
Regulation of dopamine D1 receptors by chronic administration of structurally different D1 receptor antagonists: a quantitative autoradiographic study.
European journal of pharmacology 1992;210(2):195-200.
1992: Jarmo Hietala; T Seppäla; J Lappalainen; Erkka Syvälahti
Quantification of SCH 39166, a novel selective D1 dopamine receptor antagonist, in rat brain and blood.
Psychopharmacology 1992;106(4):455-8.
1991: Jarmo Hietala; J Lappalainen; Erkka Syvälahti
Chronic D1-receptor blockade: effects on D2-receptor agonist-induced yawning in rats.
The Journal of pharmacy and pharmacology 1991;43(4):278-9.
1991: J Lappalainen; Jarmo Hietala; Markku Koulu; B Sjöholm; Erkka Syvälahti
Effects of acute administration of SCH 23390 on dopamine and serotonin turnover in major dopaminergic areas and mesencephalic raphe nuclei--comparison with ritanserin.
Progress in neuro-psychopharmacology & biological psychiatry 1991;15(6):861-72.
1990: J Lappalainen; Jarmo Hietala; Markku Koulu; Erkka Syvälahti
Neurochemical effects of chronic co-administration of ritanserin and haloperidol: comparison with clozapine effects.
European journal of pharmacology 1990;190(3):403-7.
1990: Jarmo Hietala; J Lappalainen; Markku Koulu; Erkka Syvälahti
Dopamine D1 receptor antagonism in schizophrenia: is there reduced risk of extrapyramidal side-effects?
Trends in pharmacological sciences 1990;11(10):406-10.
1990: Markku Koulu; J Lappalainen; Jarmo Hietala; B Sjöholm; Raine Virtanen
5-HT3 receptor antagonist ondansetron does not alter effects of amphetamine on DA metabolism.
Neuroreport 1990;1(2):126-8.
1990: J Lappalainen; Jarmo Hietala; B Sjöholm; Erkka Syvälahti
Effects of chronic SCH 23390 treatment on dopamine autoreceptor function in rat brain.
European journal of pharmacology 1990;179(3):315-21.
1990: J Lappalainen; Jarmo Hietala; Markku Koulu; T Seppälä; B Sjöholm; Erkka Syvälahti
Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain.
The Journal of pharmacology and experimental therapeutics 1990;252(2):845-52.
1990: Jarmo Hietala; I Salonen; J Lappalainen; Erkka Syvälahti
Ethanol administration does not alter dopamine D1 and D2 receptor characteristics in rat brain.
Neuroscience letters 1990;108(3):289-94.
1990: Markku Koulu; J Lappalainen; Jarmo Hietala; B Sjöholm
Effects of chronic administration of ondansetron (GR38032F), a selective 5-HT3 receptor antagonist, on monoamine metabolism in mesolimbic and nigrostriatal dopaminergic neurons and on striatal D2-receptor binding.
Psychopharmacology 1990;101(2):168-71.
1989: J Lappalainen; Jarmo Hietala; Erkka Syvälahti
Differential tolerance to cataleptic effects of SCH 23390 and haloperidol after repeated administration.
Psychopharmacology 1989;98(4):472-5.
1989: Jarmo Hietala; Erkka Syvälahti; M Röyttä
Dopamine D2 and muscarinic receptor binding characteristics in rat brain after withdrawal of subchronic fluphenazine and sulpiride treatment.
Progress in neuro-psychopharmacology & biological psychiatry 1989;13(1-2):247-58.
1988: Jarmo Hietala
Effects of DA-1- and DA-2-dopamine antagonists on apomorphine-induced inhibition of peripheral sympathetic neurotransmission.
Journal of autonomic pharmacology 1988;8(4):297-302.
1988: Markku Koulu; J Lappalainen; Ullamari Pesonen; Jarmo Hietala; Erkka Syvälahti
Chronic treatment with SCH 23390, a selective dopamine D-1 receptor antagonist, decreases dopamine metabolism in rat caudate nucleus.
European journal of pharmacology 1988;155(3):313-6.
1988: Erkka Syvälahti; Jarmo Hietala; M Röyttä; J Grönroos
Decrease in the number of rat brain dopamine and muscarinic receptors after chronic alcohol intake.
Pharmacology & toxicology 1988;62(4):210-2.
1988: Jarmo Hietala; Erkka Syvälahti; M Röyttä
Comparison of neuroleptic binding characteristics in rat striatum and renal cortex.
Journal of receptor research 1988;8(6):753-71.
1987: Mika Scheinin; R Lindberg; Erkka Syvälahti; Jarmo Hietala; KK Pihlajamäki; H Scheinin
Noradrenergic and dopaminergic effects of nomifensine in healthy volunteers.
Clinical pharmacology and therapeutics 1987;41(1):88-96.
1986: Erkka Syvälahti; E Säkö; Mika Scheinin; KK Pihlajamäki; Jarmo Hietala
Effects of intravenous and subcutaneous administration of apomorphine on the clinical symptoms of chronic schizophrenics.
The British journal of psychiatry : the journal of mental science 1986;148():204-8.
1985: Mika Scheinin; Erkka Syvälahti; Jarmo Hietala; R Huupponen; KK Pihlajamäki; O P Seppälä; E Säkö
Effects of apomorphine on blood levels of homovanillic acid, growth hormone and prolactin in medicated schizophrenics and healthy control subjects.
Progress in neuro-psychopharmacology & biological psychiatry 1985;9(4):441-9.