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Sakari Hietanen

Research Profile

Living Beings

Papillomaviridae

Anatomy

Procedures

Polymerase Chain Reaction

Chemicals & Drugs

Genes & Molecular Sequences

Genes, p53

Disorders

Physiology

Mutation

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Arto Leminen; Johanna Mäenpää; Ulla Puistola; Maarit Vuento; Piia Vuorela; Annika Auranen; Ralf Bützow; Sakari Hietanen; Marja Komulainen; Tapio Kuoppala; Merja Yliskoski
[Update on current care guidelines: ovarian cancer].
Riku Koivusalo; Antoine Mialon; Hanna Pitkänen; Jukka Westermarck; Sakari Hietanen
Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists.
Annika Auranen; Sakari Hietanen; Tuula Salmi; Seija Grénman
Hormonal treatments and epithelial ovarian cancer risk.

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All Publications

2012: Arto Leminen; Johanna Mäenpää; Ulla Puistola; Maarit Vuento; Piia Vuorela; Annika Auranen; Ralf Bützow; Sakari Hietanen; Marja Komulainen; Tapio Kuoppala; Merja Yliskoski
[Update on current care guidelines: ovarian cancer].
Duodecim; lääketieteellinen aikakauskirja 2012;128(12):1300-1.
2006: Riku Koivusalo; Antoine Mialon; Hanna Pitkänen; Jukka Westermarck; Sakari Hietanen
Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists.
Cancer research 2006;66(24):11817-24.
2005: Annika Auranen; Sakari Hietanen; Tuula Salmi; Seija Grénman
Hormonal treatments and epithelial ovarian cancer risk.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2005;15(5):692-700.
2005: Riku Koivusalo; Eberhard Krausz; Hans Helenius; Sakari Hietanen
Chemotherapy compounds in cervical cancer cells primed by reconstitution of p53 function after short interfering RNA-mediated degradation of human papillomavirus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs.
Molecular pharmacology 2005;68(2):372-82.
2005: Antoine Mialon; Matti Sankinen; Henrik Söderström; Teemu T Junttila; Tim H Holmström; Riku Koivusalo; Anastassios C Papageorgiou; Randall S Johnson; Sakari Hietanen; Klaus Elenius; Jukka Westermarck
DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation.
Molecular and cellular biology 2005;25(12):5040-51.
2004: Riku Koivusalo; Sakari Hietanen
The cytotoxicity of chemotherapy drugs varies in cervical cancer cells depending on the p53 status.
Cancer biology & therapy 2004;3(11):1177-83.
2004: Seija Meltomaa; Sakari Hietanen; Mikko O Taalikka; Mervi Haarala; Pentti Kiilholma; Juha I Mäkinen
Hysterectomy for gynaecological cancer: a follow-up study of subjective and objective outcome.
The Australian & New Zealand journal of obstetrics & gynaecology 2004;44(3):214-21.
2003: Pekka Klemi; Kalle Alanen; Sakari Hietanen; Seija Grénman; Matti Varpula; Tuula Salmi
Response of estrogen receptor-positive intraabdominal fibromatosis to aromatase inhibitor therapy.
Obstetrics and gynecology 2003;102(5 Pt 2):1155-8.
2002: Riku Koivusalo; Eberhard Krausz; Pertti Ruotsalainen; Hans Helenius; Sakari Hietanen
Chemoradiation of cervical cancer cells: targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand.
Cancer research 2002;62(24):7364-71.
2002: Virpi Rantanen; P Engblom; Misa Raitanen; Sakari Hietanen; M Haarala; Seija Grénman; Stina Syrjänen
Mutations of TP53 do not correlate with the sensitivity to paclitaxel--a study using 27 gynaecological cancer cell lines.
European journal of cancer (Oxford, England : 1990) 2002;38(13):1783-91.
2002: Panu Peitsaro; Sakari Hietanen; Bo Johansson; Taina Lakkala; Stina Syrjänen
Single copy heterozygote integration of HPV 33 in chromosomal band 5p14 is found in an epithelial cell clone with selective growth advantage.
Carcinogenesis 2002;23(6):1057-64.
2000: Sakari Hietanen; Sonia Lain; Eberhard Krausz; Christine Blattner; David P Lane
Activation of p53 in cervical carcinoma cells by small molecules.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8501-6.
1999: S Lu; Jaakko Tiekso; Sakari Hietanen; Kari Syrjänen; Väinö K Havu; Stina Syrjänen
Expression of cell-cycle proteins p53, p21 (WAF-1), PCNA and Ki-67 in benign, premalignant and malignant skin lesions with implicated HPV involvement.
Acta dermato-venereologica 1999;79(4):268-73.
1999: Nina Johansson; MO Vaalamo; Seija Grénman; Sakari Hietanen; Pekka Klemi; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.
The American journal of pathology 1999;154(2):469-80.
1998: Virpi Rantanen; Seija Grénman; Kaisa Kurvinen; Sakari Hietanen; Misa Raitanen; Stina Syrjänen
p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.
Gynecologic oncology 1998;71(3):352-8.
1998: Sakari Hietanen; E Auvinen; Kari Syrjänen; Stina Syrjänen
Anti-proliferative effect of retinoids and interferon-alpha-2a on vaginal cell lines derived from squamous intra-epithelial lesions.
International journal of cancer. Journal international du cancer 1998;78(3):338-45.
1998: Sakari Hietanen; Kari Syrjänen; Stina Syrjänen
Characterization of keratin and cell cycle protein expression in cell lines from squamous intraepithelial lesions progressing towards a malignant phenotype.
British journal of cancer 1998;77(5):766-75.
1998: E Auvinen; Sakari Hietanen; Lutz Gissmann; Angel Alonso
Human papillomavirus type 33 DNA and E6-E7 transcripts in late passages of the UT-DEC-1 vaginal keratinocyte cell line.
Molecular and cellular probes 1998;12(1):59-62.
1997: Sakari Hietanen; Ulla Ekblad; Tarja-Terttu Pelliniemi; Kari Syrjänen; Hans Helenius; Stina Syrjänen
Type I diabetic pregnancy and subclinical human papillomavirus infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;24(2):153-6.
1995: Sakari Hietanen; K Kurvinen; Kari Syrjänen; Seija Grénman; Thomas Carey; K McClatchey; Stina Syrjänen
Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells.
American journal of obstetrics and gynecology 1995;173(5):1477-82.
1995: Sakari Hietanen; Seija Grénman; Kari Syrjänen; K Lappalainen; J Kauppinen; Thomas Carey; Stina Syrjänen
Human papillomavirus in vulvar and vaginal carcinoma cell lines.
British journal of cancer 1995;72(1):134-9.
1995: K Kurvinen; Sakari Hietanen; Kari Syrjänen; Stina Syrjänen
Rapid and effective detection of mutations in the p53 gene using nonradioactive single-strand conformation polymorphism (SSCP) technique applied on PhastSystem.
Journal of virological methods 1995;51(1):43-53.
1992: Sakari Hietanen; E Auvinen; Seija Grénman; T Lakkala; Antti Sajantila; Pekka Klemi; J Mäenpää
Isolation of two keratinocyte cell lines derived from HPV-positive dysplastic vaginal lesions.
International journal of cancer. Journal international du cancer 1992;52(3):391-8.