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Philip Hieter

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Saccharomyces cerevisiae

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TOP 3
Sue Jinks-Robertson; Philip Hieter
The 2013 Thomas hunt morgan medal: Thomas douglas petes.
Nigel J O'Neil; Derek M van Pel; Philip Hieter
Synthetic lethality and cancer: cohesin and PARP at the replication fork.
Sean W Minaker; Shay Ben-Aroya; Megan C Filiatrault; Philip Hieter; Peter C Stirling
Biogenesis of RNA polymerases II and III requires the conserved GPN small GTPases in Saccharomyces cerevisiae.

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All Publications

2013: Sue Jinks-Robertson; Philip Hieter
The 2013 Thomas hunt morgan medal: Thomas douglas petes.
Genetics 2013;194(1):1-4.
2013: Nigel J O'Neil; Derek M van Pel; Philip Hieter
Synthetic lethality and cancer: cohesin and PARP at the replication fork.
Trends in genetics : TIG 2013;29(5):290-7.
2013: Sean W Minaker; Shay Ben-Aroya; Megan C Filiatrault; Philip Hieter; Peter C Stirling
Biogenesis of RNA polymerases II and III requires the conserved GPN small GTPases in Saccharomyces cerevisiae.
Genetics 2013;193(3):853-64.
2013: Derek M van Pel; Sean W Minaker; Payal Sipahimalani; Peter C Stirling; Philip Hieter
Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork.
G3 (Bethesda, Md.) 2013;3(2):273-82.
2013: Derek M van Pel; Irene Barrett; Brent J Guppy; Kirk J McManus; Tom Pfeifer; Babu V Sajesh; Yoko Shimizu; Philip Hieter
An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development.
PLoS genetics 2013;9(1):e1003254.
2012: Matthieu Le Gallo; Maria J Merino; James C Mullikin; Andrea J O'Hara; Nigel J O'Neil; Jessica C Price; Meghan L Rudd; Dennis C Sgroi; Mary Ellen Urick; Suiyuan Zhang; Bryant M England; Andrew K Godwin; Nancy F Hansen; Philip Hieter; Daphne W Bell
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.
Nature genetics 2012;44(12):1310-5.
2012: Peter C Stirling; Cheryl M Tucker; Forrest Spencer; Munira A Basrai; Matthew J Crisp; Maitreya J Dunham; Philip Hieter
Mutability and mutational spectrum of chromosome transmission fidelity genes.
Chromosoma 2012;121(3):263-75.
2012: Peter C Stirling; Michael S Kobor; Sean W Minaker; Payal Sipahimalani; Maria J Aristizabal; Irene Barrett; Yujia A Chan; Philip Hieter
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.
Genes & development 2012;26(2):163-75.
2012: Jessica L McLellan; Nigel J O'Neil; Ann M Rose; Payal Sipahimalani; Kevin Ushey; Derek M van Pel; Irene Barrett; Jennifer Bryan; Elizabeth Ferree; Philip Hieter
Synthetic lethality of cohesins with PARPs and replication fork mediators.
PLoS genetics 2012;8(3):e1002574.
2011: Peter C Stirling; Michelle S Bloom; Tejomayee Solanki-Patil; Stephanie Smith; Payal Sipahimalani; Zhijian Li; Megan Kofoed; Shay Ben-Aroya; Kyungjae Myung; Philip Hieter
The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components.
PLoS genetics 2011;7(4):e1002057.
2010: Shay Ben-Aroya; Neta Agmon; Karen Yuen; Teresa Kwok; Kirk McManus; Martin Kupiec; Philip Hieter
Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair.
PLoS genetics 2010;6(2):e1000852.
2010: Yearit Fridman; Niv Palgi; Daniel Dovrat; Shay Ben-Aroya; Philip Hieter; Amir Aharoni
Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair.
PLoS biology 2010;8(10):e1000507.
2010: Shay Ben-Aroya; Xuewen Pan; Jef Boeke; Philip Hieter
Making temperature-sensitive mutants.
Methods in enzymology 2010;470():181-204.
2009: Jessica McLellan; Nigel O'Neil; Sanja Tarailo; Jan Stoepel; Jennifer Bryan; Ann Rose; Philip Hieter
Synthetic lethal genetic interactions that decrease somatic cell proliferation in Caenorhabditis elegans identify the alternative RFC CTF18 as a candidate cancer drug target.
Molecular biology of the cell 2009;20(24):5306-13.
2009: Kirk J McManus; Irene Barrett; Yasaman Nouhi; Philip Hieter
Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3276-81.
2008: Shay Ben-Aroya; Candice Coombes; Teresa Kwok; Kathryn A O'Donnell; Jef Boeke; Philip Hieter
Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae.
Molecular cell 2008;30(2):248-58.
2008: Thomas D Barber; Kirk McManus; Karen W Y Yuen; Marcelo Reis; Giovanni Parmigiani; Dong Shen; Irene Barrett; Yasaman Nouhi; Forrest Spencer; Sanford Markowitz; Victor E Velculescu; Kenneth W Kinzler; Bert Vogelstein; Christoph Lengauer; Philip Hieter
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(9):3443-8.
2008: Sanja Rogic; Ben Montpetit; Holger H Hoos; Alan K Mackworth; B F Francis Ouellette; Philip Hieter
Correlation between the secondary structure of pre-mRNA introns and the efficiency of splicing in Saccharomyces cerevisiae.
BMC genomics 2008;9():355.
2007: Sean R Collins; Kyle M Miller; Nancy L Maas; Assen Roguev; Jeffrey Fillingham; Clement S Chu; Maya Schuldiner; Marinella Gebbia; Judith Recht; Michael Shales; Huiming Ding; Hong Xu; Junhong Han; Kristin Ingvarsdottir; Benjamin Cheng; Brenda Andrews; Charles Boone; Shelley L Berger; Philip Hieter; Zhiguo Zhang; Grant W Brown; C James Ingles; Andrew Emili; C David Allis; David P Toczyski; Jonathan S Weissman; Jack F Greenblatt; Nevan J Krogan
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.
Nature 2007;446(7137):806-10.
2007: Karen W Y Yuen; Cheryl D Warren; Ou Chen; Teresa Kwok; Philip Hieter; Forrest Spencer
Systematic genome instability screens in yeast and their potential relevance to cancer.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3925-30.
2006: David Martin; Kristin Baetz; Xiaobing Shi; Kay L Walter; Vicki E MacDonald; Martin J Wlodarski; Or Gozani; Philip Hieter; LeAnn Howe
The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.
Molecular and cellular biology 2006;26(21):7871-9.
2006: Ben Montpetit; Tony R Hazbun; Stanley Fields; Philip Hieter
Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation.
The Journal of cell biology 2006;174(5):653-63.
2006: ALLAN SPRADLING; Barry Ganetsky; Philip Hieter; Mark Johnston; Maynard Olson; Terry L. Orr-Weaver; Janet Rossant; Alejandro Sanchez; Robert Waterston
New roles for model genetic organisms in understanding and treating human disease: report from the 2006 Genetics Society of America meeting.
Genetics 2006;172(4):2025-32.
2005: Karen W Y Yuen; Ben Montpetit; Philip Hieter
The kinetochore and cancer: what's the connection?
Current opinion in cell biology 2005;17(6):576-82.
2005: Jan Stoepel; Michelle Ottey; Cornelia Kurischko; Philip Hieter; Francis C Luca
The mitotic exit network Mob1p-Dbf2p kinase complex localizes to the nucleus and regulates passenger protein localization.
Molecular biology of the cell 2005;16(12):5465-79.
2005: Isabelle Pot; James Knockleby; Victoria Aneliunas; Thao Nguyen; Sonia Ah-Kye; Gregory Liszt; Michael Snyder; Philip Hieter; Jackie Vogel
Spindle checkpoint maintenance requires Ame1 and Okp1.
Cell cycle (Georgetown, Tex.) 2005;4(10):1448-56.
2005: Ben Montpetit; Ken Thorne; Irene Barrett; Kim Andrews; Ravi Jadusingh; Philip Hieter; Vivien Measday
Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.
Genetics 2005;171(2):489-501.
2005: Vivien Measday; Kristin Baetz; Julie Guzzo; Karen Yuen; Teresa Kwok; Bilal Sheikh; Huiming Ding; Ryo Ueta; Trinh Hoac; Benjamin Cheng; Isabelle Pot; Amy Tong; Yuko Yamaguchi-Iwai; Charles Boone; Philip Hieter; Brenda Andrews
Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13956-61.
2005: Andrew M Page; Vicky Aneliunas; john lamb; Philip Hieter
In vivo characterization of the nonessential budding yeast anaphase-promoting complex/cyclosome components Swm1p, Mnd2p and Apc9p.
Genetics 2005;170(3):1045-62.
2005: Eugene C Yi; Xiao-Jun Li; Kelly Cooke; Hookeun Lee; Brian Raught; Andrew Page; Victoria Aneliunas; Philip Hieter; David R Goodlett; Ruedi Aebersold
Increased quantitative proteome coverage with (13)C/(12)C-based, acid-cleavable isotope-coded affinity tag reagent and modified data acquisition scheme.
Proteomics 2005;5(2):380-7.
2005: Doug Bassett; James C Morrell; Gregory J Gatto; Jianwu Bai; Brian V Geisbrecht; Philip Hieter; Stephen J Gould
Detecting patterns of protein distribution and gene expression in silico.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):516.
2004: Xuewen Pan; Daniel S Yuan; Dong Xiang; Xiaoling Wang; Sharon Sookhai-Mahadeo; Joel S Bader; Philip Hieter; Forrest Spencer; Jef Boeke
A robust toolkit for functional profiling of the yeast genome.
Molecular cell 2004;16(3):487-96.
2004: Nevan J Krogan; Kristin Baetz; Michael-Christopher Keogh; Nira Datta; Chika Sawa; Trevor C Y Kwok; Natalie J Thompson; Michael G Davey; Jeff Pootoolal; Timothy R Hughes; Andrew Emili; Stephen Buratowski; Philip Hieter; Jack F Greenblatt
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(37):13513-8.
2004: Melanie L Mayer; Isabelle Pot; Michael Chang; Hong Xu; Victoria Aneliunas; Teresa Kwok; Rick Newitt; Ruedi Aebersold; Charles Boone; Grant W Brown; Philip Hieter
Identification of protein complexes required for efficient sister chromatid cohesion.
Molecular biology of the cell 2004;15(4):1736-45.
2004: Kristin Baetz; Lianne M McHardy; Ken Gable; Tamsin Tarling; Delphine Rebérioux; Jenny Bryan; Raymond J Andersen; Teresa Dunn; Philip Hieter; Michel Roberge
Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4525-30.
2004: Vivien Measday; Philip Hieter
Kinetochore sub-structure comes to MIND.
Nature cell biology 2004;6(2):94-5.
2004: Kristin Baetz; Nevan J Krogan; Andrew Emili; Jack Greenblatt; Philip Hieter
The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion.
Molecular and cellular biology 2004;24(3):1232-44.
2003: Katsumi Kitagawa; Rashid Abdulle; Parmil K Bansal; Gerard Cagney; Stanley Fields; Philip Hieter
Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint.
Molecular cell 2003;11(5):1201-13.
2003: Isabelle Pot; Vivien Measday; Brian E Snydsman; Gerard Cagney; Stanley Fields; Trisha Davis; Eric G D Muller; Philip Hieter
Chl4p and iml3p are two new members of the budding yeast outer kinetochore.
Molecular biology of the cell 2003;14(2):460-76.
2002: Teri Melese; Philip Hieter
From genetics and genomics to drug discovery: yeast rises to the challenge.
Trends in pharmacological sciences 2002;23(12):544-7.
2002: Kevin Schadick; H Matthew Fourcade; Peter Boumenot; Jeffrey J Seitz; Jennifer L Morrell; Louise Chang; Kathleen L Gould; Janet F Partridge; Robin C Allshire; Katsumi Kitagawa; Philip Hieter; Charles Hoffman
Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation.
Eukaryotic cell 2002;1(4):558-67.
2002: Leana M Topper; Michael S Campbell; Tugendreich Stuart; John R Daum; Daniel J Burke; Philip Hieter; Gary J Gorbsky
The dephosphorylated form of the anaphase-promoting complex protein Cdc27/Apc3 concentrates on kinetochores and chromosome arms in mitosis.
Cell cycle (Georgetown, Tex.) 2002;1(4):282-92.
2002: Nasrin Sarafan-Vasseur; Aude Lamy; Jeannette Bourguignon; Florence Le Pessot; Philip Hieter; Richard Sesboüé; Christian Bastard; Thierry Frébourg; Jean-Michel Flaman
Overexpression of B-type cyclins alters chromosomal segregation.
Oncogene 2002;21(13):2051-7.
2002: Munira A Basrai; Philip Hieter
Transcriptome analysis of Saccharomyces cerevisiae using serial analysis of gene expression.
Methods in enzymology 2002;350():414-44.
2002: Vivien Measday; Philip Hieter
Synthetic dosage lethality.
Methods in enzymology 2002;350():316-26.
2002: Vivien Measday; Dale W Hailey; Isabelle Pot; Scott A Givan; Katherine M Hyland; Gerard Cagney; Stanley Fields; Trisha Davis; Philip Hieter
Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.
Genes & development 2002;16(1):101-13.
2001: M L Mayer; Steven P Gygi; R Aebersold; Philip Hieter
Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae.
Molecular cell 2001;7(5):959-70.
2001: Oliver Kerscher; Philip Hieter; Mark Winey; Munira A Basrai
Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation.
Genetics 2001;157(4):1543-53.
2000: John R Daum; Tugendreich Stuart; Leana M Topper; P M Jorgensen; C Hoog; Philip Hieter; Gary J Gorbsky
The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome.
Current biology : CB 2000;10(23):R850-2.
2000: JD Leverson; Claudio A P Joazeiro; Andrew M Page; H k Huang; Philip Hieter; Tony Hunter
The APC11 RING-H2 finger mediates E2-dependent ubiquitination.
Molecular biology of the cell 2000;11(7):2315-25.
2000: R Ploger; J Zhang; D Bassett; Roger H Reeves; Philip Hieter; Mark S Boguski; Forrest Spencer
XREFdb: cross-referencing the genetics and genes of mammals and model organisms.
Nucleic acids research 2000;28(1):120-2.
1999: Munira A Basrai; Victor E Velculescu; Kenneth W Kinzler; Philip Hieter
NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.
Molecular and cellular biology 1999;19(10):7041-9.
1999: Philip Hieter; T Griffiths
Polyploidy--more is more or less.
Science (New York, N.Y.) 1999;285(5425):210-1.
1999: Katsumi Kitagawa; Dorota Skowyra; Stephen J Elledge; J Wade Harper; Philip Hieter
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.
Molecular cell 1999;4(1):21-33.
1999: K M Hyland; J Kingsbury; Douglas Koshland; Philip Hieter
Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle.
The Journal of cell biology 1999;145(1):15-28.
1999: Michael T Geraghty; D Bassett; James C Morrell; Gregory J Gatto; Jianwu Bai; Brian V Geisbrecht; Philip Hieter; Stephen J Gould
Detecting patterns of protein distribution and gene expression in silico.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2937-42.
1999: Robert V Skibbens; LB Corson; Douglas Koshland; Philip Hieter
Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery.
Genes & development 1999;13(3):307-19.
1999: Andrew M Page; Philip Hieter
The anaphase-promoting complex: new subunits and regulators.
Annual review of biochemistry 1999;68():583-609.
1998: H Yu; J M Peters; Randall W King; Andrew M Page; Philip Hieter; Marc W Kirschner
Identification of a cullin homology region in a subunit of the anaphase-promoting complex.
Science (New York, N.Y.) 1998;279(5354):1219-22.
1998: S Kotani; Tugendreich Stuart; M Fujii; P M Jorgensen; N Watanabe; C Hoog; Philip Hieter; Kazuo Todokoro
PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.
Molecular cell 1998;1(3):371-80.
1998: Robert V Skibbens; Philip Hieter
Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery.
Annual review of genetics 1998;32():307-37.
1997: Philip Hieter; Mark S Boguski
Functional genomics: it's all how you read it.
Science (New York, N.Y.) 1997;278(5338):601-2.
1997: T Woodage; Munira A Basrai; Andreas D Baxevanis; Philip Hieter; Francis S Collins
Characterization of the CHD family of proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11472-7.
1997: D M Morrow; C Connelly; Philip Hieter
"Break copy" duplication: a model for chromosome fragment formation in Saccharomyces cerevisiae.
Genetics 1997;147(2):371-82.
1997: Munira A Basrai; Philip Hieter; Jef Boeke
Small open reading frames: beautiful needles in the haystack.
Genome research 1997;7(8):768-71.
1997: D E Bassett; Mark S Boguski; Forrest Spencer; Roger H Reeves; S Kim; T Weaver; Philip Hieter
Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease.
Nature genetics 1997;15(4):339-44.
1997: Victor E Velculescu; Lin Zhang; Wei Zhou; J Vogelstein; Munira A Basrai; D E Bassett; Philip Hieter; Bert Vogelstein; Kenneth W Kinzler
Characterization of the yeast transcriptome.
Cell 1997;88(2):243-51.
1997: Andrew M Page; Philip Hieter
The anaphase promoting complex.
Cancer surveys 1997;29():133-50.
1997: D E Bassett; Mark S Boguski; Philip Hieter
Identifying human homologs of cell cycle genes using dbEST and XREFdb.
Methods in enzymology 1997;283():128-40.
1996: George S Brush; D M Morrow; Philip Hieter; Thomas J Kelly
The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(26):15075-80.
1996: D E Bassett; Munira A Basrai; C Connelly; K M Hyland; Katsumi Kitagawa; M L Mayer; D M Morrow; Andrew M Page; V A Resto; Robert V Skibbens; Philip Hieter
Exploiting the complete yeast genome sequence.
Current opinion in genetics & development 1996;6(6):763-6.
1996: C Connelly; Philip Hieter
Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression.
Cell 1996;86(2):275-85.
1996: Philip Hieter; D E Bassett; David Valle
The yeast genome--a common currency.
Nature genetics 1996;13(3):253-5.
1996: Grant A Hartzog; Munira A Basrai; S L Ricupero-Hovasse; Philip Hieter; fred winston
Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.
Molecular and cellular biology 1996;16(6):2848-56.
1996: Munira A Basrai; J Kingsbury; Douglas Koshland; Forrest Spencer; Philip Hieter
Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae.
Molecular and cellular biology 1996;16(6):2838-47.
1996: E S Kroll; K M Hyland; Philip Hieter; J J Li
Establishing genetic interactions by a synthetic dosage lethality phenotype.
Genetics 1996;143(1):95-102.
1995: Peter K Sorger; Kimberly F Doheny; Philip Hieter; K M Kopski; T C Huffaker; Anthony A Hyman
Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12026-30.
1995: D M Morrow; D A Tagle; Y Shiloh; Francis S Collins; Philip Hieter
TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1.
Cell 1995;82(5):831-40.
1995: D E Bassett; Mark S Boguski; Forrest Spencer; Roger H Reeves; M Goebl; Philip Hieter
Comparative genomics, genome cross-referencing and XREFdb.
Trends in genetics : TIG 1995;11(9):372-3.
1995: Munira A Basrai; Philip Hieter
Is there a unique form of chromatin at the Saccharomyces cerevisiae centromeres?
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(8):669-72.
1995: john lamb; Tugendreich Stuart; Philip Hieter
Tetratrico peptide repeat interactions: to TPR or not to TPR?
Trends in biochemical sciences 1995;20(7):257-9.
1995: Randall W King; J M Peters; Tugendreich Stuart; M Rolfe; Philip Hieter; Marc W Kirschner
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B.
Cell 1995;81(2):279-88.
1995: Tugendreich Stuart; John E Tomkiel; William C Earnshaw; Philip Hieter
CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition.
Cell 1995;81(2):261-8.
1995: R S Sikorski; W A Michaud; Tugendreich Stuart; Philip Hieter
Allele shuffling: conjugational transfer, plasmid shuffling and suppressor analysis in Saccharomyces cerevisiae.
Gene 1995;155(1):51-9.
1995: Dorothy Sears; Johannes H Hegemann; J H Shero; Philip Hieter
Cis-acting determinants affecting centromere function, sister-chromatid cohesion and reciprocal recombination during meiosis in Saccharomyces cerevisiae.
Genetics 1995;139(3):1159-73.
1994: Dorothy Sears; Philip Hieter; Giora Simchen
An implanted recombination hot spot stimulates recombination and enhances sister chromatid cohesion of heterologous YACs during yeast meiosis.
Genetics 1994;138(4):1055-65.
1994: john lamb; W A Michaud; R S Sikorski; Philip Hieter
Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis.
The EMBO journal 1994;13(18):4321-8.
1994: Forrest Spencer; Y Hugerat; Giora Simchen; O Hurko; C Connelly; Philip Hieter
Yeast kar1 mutants provide an effective method for YAC transfer to new hosts.
Genomics 1994;22(1):118-26.
1994: Gary Ketner; Forrest Spencer; Tugendreich Stuart; C Connelly; Philip Hieter
Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6186-90.
1994: J W Puziss; T A Hardy; R B Johnson; P J Roach; Philip Hieter
MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase 3.
Molecular and cellular biology 1994;14(1):831-9.
1994: Tugendreich Stuart; D E Bassett; Victor A McKusick; Mark S Boguski; Philip Hieter
Genes conserved in yeast and humans.
Human molecular genetics 1994;3 Spec No():1509-17.
1993: Tugendreich Stuart; Mark S Boguski; Michael F Seldin; Philip Hieter
Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10031-5.
1993: I L Gonzalez; Tugendreich Stuart; Philip Hieter; J E Sylvester
Fixation times of retroposons in the ribosomal DNA spacer of human and other primates.
Genomics 1993;18(1):29-36.
1993: Kimberly F Doheny; Peter K Sorger; Anthony A Hyman; Tugendreich Stuart; Forrest Spencer; Philip Hieter
Identification of essential components of the S. cerevisiae kinetochore.
Cell 1993;73(4):761-74.
1993: R S Sikorski; W A Michaud; Philip Hieter
p62cdc23 of Saccharomyces cerevisiae: a nuclear tetratricopeptide repeat protein with two mutable domains.
Molecular and cellular biology 1993;13(2):1212-21.
1993: Natalay Kouprina; A Tsouladze; M Koryabin; Philip Hieter; Forrest Spencer; Vladimir Larionov
Identification and genetic mapping of CHL genes controlling mitotic chromosome transmission in yeast.
Yeast (Chichester, England) 1993;9(1):11-9.
1992: Natalay Kouprina; E Kroll; V Bannikov; V Bliskovsky; Rinat Z Gizatullin; A Kirillov; B Shestopalov; V Zakharyev; Philip Hieter; Forrest Spencer
CTF4 (CHL15) mutants exhibit defective DNA metabolism in the yeast Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(12):5736-47.
1992: Forrest Spencer; Philip Hieter
Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):8908-12.
1992: Dorothy Sears; Johannes H Hegemann; Philip Hieter
Meiotic recombination and segregation of human-derived artificial chromosomes in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5296-300.
1992: T W Christianson; R S Sikorski; M Dante; J H Shero; Philip Hieter
Multifunctional yeast high-copy-number shuttle vectors.
Gene 1992;110(1):119-22.
1992: Roger H Reeves; william pavan; Philip Hieter
Yeast artificial chromosome modification and manipulation.
Methods in enzymology 1992;216():584-603.
1991: william pavan; Philip Hieter; D Sears; A Burkhoff; Roger H Reeves
High-efficiency yeast artificial chromosome fragmentation vectors.
Gene 1991;106(1):125-7.
1991: J H Shero; M K McCormick; S E Antonarakis; Philip Hieter
Yeast artificial chromosome vectors for efficient clone manipulation and mapping.
Genomics 1991;10(2):505-8.
1991: C Connelly; M K McCormick; J Shero; Philip Hieter
Polyamines eliminate an extreme size bias against transformation of large yeast artificial chromosome DNA.
Genomics 1991;10(1):10-6.
1991: J H Shero; Philip Hieter
A suppressor of a centromere DNA mutation encodes a putative protein kinase (MCK1).
Genes & development 1991;5(4):549-60.
1991: J H Shero; Michael Koval; Forrest Spencer; R E Palmer; Philip Hieter; Douglas Koshland
Analysis of chromosome segregation in Saccharomyces cerevisiae.
Methods in enzymology 1991;194():749-73.
1991: S L Gerring; C Connelly; Philip Hieter
Positional mapping of genes by chromosome blotting and chromosome fragmentation.
Methods in enzymology 1991;194():57-77.
1991: R S Sikorski; W A Michaud; J C Wootton; M S Boguski; C Connelly; Philip Hieter
TPR proteins as essential components of the yeast cell cycle.
Cold Spring Harbor symposia on quantitative biology 1991;56():663-73.
1990: S L Gerring; Forrest Spencer; Philip Hieter
The CHL 1 (CTF 1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2/M.
The EMBO journal 1990;9(13):4347-58.
1990: M K McCormick; S E Antonarakis; Philip Hieter
YAC cloning of DNA embedded in an agarose matrix.
Genetic analysis, techniques and applications 1990;7(5):114-8.
1990: Roger H Reeves; william pavan; Philip Hieter
Modification and manipulation of mammalian DNA cloned as YACs.
Genetic analysis, techniques and applications 1990;7(5):107-13.
1990: william pavan; Philip Hieter; Roger H Reeves
Modification and transfer into an embryonal carcinoma cell line of a 360-kilobase human-derived yeast artificial chromosome.
Molecular and cellular biology 1990;10(8):4163-9.
1990: Forrest Spencer; S L Gerring; C Connelly; Philip Hieter
Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae.
Genetics 1990;124(2):237-49.
1990: william pavan; Philip Hieter; Roger H Reeves
Generation of deletion derivatives by targeted transformation of human-derived yeast artificial chromosomes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1300-4.
1990: R S Sikorski; M S Boguski; M Goebl; Philip Hieter
A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis.
Cell 1990;60(2):307-17.
1989: M K McCormick; J H Shero; M C Cheung; Y W Kan; Philip Hieter; S E Antonarakis
Construction of human chromosome 21-specific yeast artificial chromosomes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9991-5.
1989: G Cottarel; J H Shero; Philip Hieter; Johannes H Hegemann
A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic centromere functions in Saccharomyces cerevisiae.
Molecular and cellular biology 1989;9(8):3342-9.
1989: R S Sikorski; Philip Hieter
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.
Genetics 1989;122(1):19-27.
1989: Forrest Spencer; C Connelly; S Gerring; J Shero; R Sikorski; Philip Hieter
Chromosomal aneuploidy in Saccharomyces cerevisiae.
Progress in clinical and biological research 1989;318():293-306.
1989: S E Antonarakis; AC Warren; M K McCormick; J G Lewis; Philip Hieter; Aravinda Chakravarti
Molecular mapping of chromosome 21 and the region responsible for Down syndrome.
Progress in clinical and biological research 1989;311():29-43.
1988: Johannes H Hegemann; J H Shero; G Cottarel; Peter Philippsen; Philip Hieter
Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.
Molecular and cellular biology 1988;8(6):2523-35.
1985: Philip Hieter; D Pridmore; Johannes H Hegemann; M Thomas; R W Davis; Peter Philippsen
Functional selection and analysis of yeast centromeric DNA.
Cell 1985;42(3):913-21.