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Jitsuo Higaki

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Akiyoshi Ogimoto; Jitsuo Higaki
[Pleiotropic effects of new generation calcium channel blockers on cardiovascular protections].
Haruhiko Higashi; Akiyoshi Ogimoto; Makoto Saito; Toyofumi Yoshii; Jun Aono; Jitsuo Higaki
Frequent urination caused by a giant iliac artery aneurysm.
Takafumi Okura; Jitsuo Higaki
[Onset of atrial fibrillation and hypertensive treatment].

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2013: Akiyoshi Ogimoto; Jitsuo Higaki
[Pleiotropic effects of new generation calcium channel blockers on cardiovascular protections].
Clinical calcium 2013;23(4):569-74.
2013: Haruhiko Higashi; Akiyoshi Ogimoto; Makoto Saito; Toyofumi Yoshii; Jun Aono; Jitsuo Higaki
Frequent urination caused by a giant iliac artery aneurysm.
Journal of the American College of Cardiology 2013;61(10):e151.
2013: Takafumi Okura; Jitsuo Higaki
[Onset of atrial fibrillation and hypertensive treatment].
Nihon rinsho. Japanese journal of clinical medicine 2013;71(1):167-73.
2013: Seigo Miyoshi; Norihiko Nakanishi; Takafumi Okura; Toshimitsu Suwaki; Mayuki Aibiki; Kentaro Dote; Hironobu Hamada; Kazunori Irifune; Ryoji Ito; Takanori Kanematsu; Hitoshi Katayama; Jitsuo Higaki
Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis.
Drug design, development and therapy 2013;7():305-16.
2013: Katsuji Inoue; Takayuki Nagai; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Makoto Saito; Yuji Shigematsu; Takumi Sumimoto; Jun Suzuki; Toyofumi Yoshii; Jun-ichi Funada; Mareomi Hamada; Go Hiasa; Jitsuo Higaki
Impact of septal curvature on regional strain in patients with hypertrophic cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2013;77(4):1040-5.
2012: Kousei Ohshima; Kana Tsukuda; Jitsuo Higaki; Jun Iwanami; Fei Jing; Harumi Kanno; Li-Juan Min; Masaki Mogi; Hirotomo Nakaoka; Akiyoshi Ogimoto; Masatsugu Horiuchi
Inhibition of MCP-1/CCR2 signaling pathway is involved in synergistic inhibitory effects of irbesartan with rosuvastatin on vascular remodeling.
Journal of the American Society of Hypertension : JASH 2012;6(6):375-84.
2012: Haruhiko Higashi; Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Makoto Saito; Toyofumi Yoshii; Go Hiasa; Jitsuo Higaki
Acute effects of adaptive servo ventilation on hemodynamics, coronary flow, and flow reserve in a patient with idiopathic dilated cardiomyopathy.
The Canadian journal of cardiology 2012;28(5):611.e11-3.
2012: Makoto Saito; Takumi Sumimoto; Toyofumi Yoshii; Go Hiasa; Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Jitsuo Higaki
Carotid arterial circumferential strain by two-dimensional speckle tracking: a novel parameter of arterial elasticity.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(9):897-902.
2012: Shinji Inaba; Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Makoto Saito; Takumi Sumimoto; Yasunori Takata; Toyofumi Yoshii; Jun-ichi Funada; Go Hiasa; Haruhiko Higashi; Jitsuo Higaki
Impact of type 2 diabetes on serial changes in tissue characteristics of coronary plaques: an integrated backscatter intravascular ultrasound analysis.
European heart journal cardiovascular Imaging 2012;13(9):717-23.
2012: Jun Suzuki; Jitsuo Higaki
[ACE inhibitor, ARB, renin inhibitor].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 6():253-8.
2012: Seigo Miyoshi; Takafumi Okura; Hironobu Hamada; Naohiko Hamaguchi; Kazunori Irifune; Ryoji Ito; Hitoshi Katayama; Aki Kato; Tatsuhiko Miyazaki; Jitsuo Higaki
Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo.
International journal of oncology 2012;41(2):449-56.
2012: Makoto Saito; Yuji Shigematsu; Takumi Sumimoto; Toyofumi Yoshii; Haruhiko Higashi; Shinji Inaba; Katsuji Inoue; Hiroe Morioka; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Mareomi Hamada; Go Hiasa; Jitsuo Higaki
Clinical significance of global two-dimensional strain as a surrogate parameter of myocardial fibrosis and cardiac events in patients with hypertrophic cardiomyopathy.
European heart journal cardiovascular Imaging 2012;13(7):617-23.
2012: Jun Aono; Masatsugu Horiuchi; Katsuji Inoue; Masaru Iwai; Takayuki Nagai; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Jun Suzuki; Jitsuo Higaki
Deletion of the angiotensin II type 1a receptor prevents atherosclerotic plaque rupture in apolipoprotein E-/- mice.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(6):1453-9.
2012: Toshio Ogihara; Yasuo Ohashi; Hiromi Rakugi; Takao Saruta; Kazuyuki Shimada; Kazuaki Shimamoto; Hiromichi Suzuki; Seiji Umemoto; Jitsuo Higaki; Sadayoshi Ito; Akira Kamiya; Hiroaki Matsuoka; Masunori Matsuzaki
Combination therapy for hypertension in the elderly: a sub-analysis of the Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) Trial.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(4):441-8.
2012: Shinji Inaba; Teruhito Kido; Teruhito Mochizuki; Hideki Okayama; Jitsuo Higaki
Natural history of a coronary plaque followed by computed tomography.
European heart journal cardiovascular Imaging 2012;13(3):242.
2012: Kousei Ohshima; Kana Tsukuda; Jitsuo Higaki; Jun Iwanami; Fei Jing; Li-Juan Min; Masaki Mogi; Masatsugu Horiuchi
Roles of interleukin 17 in angiotensin II type 1 receptor-mediated insulin resistance.
Hypertension 2012;59(2):493-9.
2012: Mie Kurata; Tatsuhiko Miyazaki; Toshinori Nakahara; Jitsuo Higaki; Yoshiaki Kumon; Takafumi Okura; Masahiko Tagawa; Hideaki Watanabe; Masato Nose
Plasma thrombin-cleaved osteopontin elevation after carotid artery stenting in symptomatic ischemic stroke patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2012;35(2):207-12.
2012: Ryo Ogawa; Takafumi Okura; Jun Irita; Masanori Jotoku; Ken-ichi Miyoshi; Tomoaki Nagao; Jitsuo Higaki
[Ultrastructure of glomerular podocyts in the incipient phase of minimal change nephrotic syndrome with thin basement membrane disease].
Nihon Jinzo Gakkai shi 2012;54(8):1192-6.
2012: Kousei Ohshima; Ulrike Muscha Steckelings; Kana Tsukuda; Tomas Unger; Jun Iwanami; Fei Jing; Li-Juan Min; Masaki Mogi; Akiyoshi Ogimoto; Björn Dahlöf; Jitsuo Higaki; Masatsugu Horiuchi
Direct angiotensin II type 2 receptor stimulation ameliorates insulin resistance in type 2 diabetes mice with PPARγ activation.
PloS one 2012;7(11):e48387.
2012: Akiyoshi Ogimoto; Hideki Okayama; Yuji Shigematsu; Jun Suzuki; Yasuharu Tabara; Katsuji Inoue; Tetsuro Miki; Takayuki Nagai; Kazuhisa Nishimura; Jitsuo Higaki
Impact of synergistic polymorphisms in adrenergic receptor-related genes and cardiovascular events in patients with dilated cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(8):2003-8.
2012: Tomoaki Nagao; Takafumi Okura; Toshimitsu Uede; Veena Rasika Desilva; Daijiro Enomoto; Jun Irita; Masanori Jotoku; Mie Kurata; Yutaka Matsui; Ken-Ichi Miyoshi; Jitsuo Higaki
Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy.
Nephron extra 2012;2(1):87-103.
2012: Daijiro Enomoto; Jun Irita; Masanori Jotoku; Ken-Ichi Miyoshi; Tomoaki Nagao; Takafumi Okura; Jitsuo Higaki
Relationship between renal hemodynamics and urinary type IV collagen in patients with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2012;34(8):612-6.
2011: Shinji Inaba; Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Tatsunori Takahashi; Haruhiko Higashi; Jitsuo Higaki
A cluster of black holes and multiple plaque ruptures on optical coherence tomography 13 years after bare-metal stent implantation.
International journal of cardiology 2011;152(3):e47-8.
2011: Takafumi Okura; Jitsuo Higaki
[Evidence from large clinical trials for Japanese hypertensive patients].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(11):1934-40.
2011: Shinji Inaba; Masaru Iwai; Harumi Kanno; Masaki Mogi; Hideki Okayama; Izumi Senba; Megumi Furuno; Jitsuo Higaki; Masatsugu Horiuchi
Role of angiotensin-converting enzyme 2 in cardiac hypertrophy induced by nitric oxide synthase inhibition.
Journal of hypertension 2011;29(11):2236-45.
2011: Haruhiko Higashi; Shinji Inaba; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Yohei Fujita; Tomoko Hamagami; Jitsuo Higaki
Usefulness of adjunctive pulse infusion thrombolysis after failed aspiration for massive intracoronary thrombus.
The Canadian journal of cardiology 2011;27(6):869.e1-2.
2011: Jun Irita; Masanori Jotoku; Mie Kurata; Yutaka Matsui; Ken-Ichi Miyoshi; Tomoaki Nagao; Takafumi Okura; Susan R Rittiling; Toshimitsu Uede; David T Denhardt; Veena Rasika Desilva; Daijiro Enomoto; Jitsuo Higaki
Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney.
American journal of physiology. Renal physiology 2011;301(4):F833-44.
2011: Shinji Inaba; Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Kousei Ohshima; Jitsuo Higaki; Haruhiko Higashi; Hideki Okayama
Coronary steal detected by transthoracic Doppler echocardiography.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2011;12(9):E36.
2011: Kazuhisa Nishimura; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Hideki Okayama; Makoto Saito; Yuji Shigematsu; Takumi Sumimoto; Toyofumi Yoshii; Jun-ichi Funada; Go Hiasa; Shinji Inaba; Katsuji Inoue; Jitsuo Higaki
Usefulness of the MOSAIC (measurement of stenosis by aliasing coronary flow) method using transthoracic color Doppler echocardiography in unstable angina patients.
International journal of cardiology 2011;151(2):170-4.
2011: Takayuki Nagai; Michitsugu Nakamura; Kazuhisa Nishimura; Jun Suzuki; Akira Fujii; Jitsuo Higaki; Katsuji Inoue; Hironori Izutani; Kanji Kawachi; Teruhito Kido; Yuji Matsumoto; Teruhito Mochizuki; Akiyoshi Ogimoto
Large thrombus originating from left atrial diverticulum: a new concern for catheter ablation of atrial fibrillation.
Circulation 2011;124(9):1086-8.
2011: Makoto Saito; Yuji Shigematsu; Takumi Sumimoto; Toyofumi Yoshii; Shinji Inaba; Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Hideki Okayama; Jun-ichi Funada; Go Hiasa; Jitsuo Higaki
The differences in left ventricular torsional behavior between patients with hypertrophic cardiomyopathy and hypertensive heart disease.
International journal of cardiology 2011;150(3):301-6.
2011: Masunori Matsuzaki; Toshio Ogihara; Yasuo Ohashi; Hiromi Rakugi; Takao Saruta; Kazuyuki Shimada; Hiromichi Suzuki; Norihiro Suzuki; Chuwa Tei; Seiji Umemoto; Keishi Abe; Tanenao Eto; Jitsuo Higaki; Sadayoshi Ito; Akira Kamiya; Kenjiro Kikuchi; Hiroaki Matsuoka
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial.
Journal of hypertension 2011;29(8):1649-59.
2011: Yuji Shigematsu; Jun Suzuki; Mareomi Hamada; Katsuji Inoue; Takayuki Nagai; Kazuhisa Nishimura; Akiyoshi Ogimoto; Jitsuo Higaki
Risk for atrial fibrillation in patients with hypertrophic cardiomyopathy: association with insulin resistance.
Journal of cardiology 2011;58(1):18-25.
2011: Kazunori Irifune; Ryoji Ito; Hitoshi Katayama; Aki Kato; Seigo Miyoshi; Kazutaka Nishimura; Ryo Toyozawa; Akira Watanabe; Masahiro Abe; Hironobu Hamada; Naohiko Hamaguchi; Sachiko Hamaguchi; Jitsuo Higaki
Antitussive effect of bakumondoto a fixed kampo medicine (six herbal components) for treatment of post-infectious prolonged cough: controlled clinical pilot study with 19 patients.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;18(8-9):630-3.
2011: Shinji Inaba; Masaru Iwai; Megumi Furuno; Harumi Kanno; Izumi Senba; Hideki Okayama; Masaki Mogi; Jitsuo Higaki; Masatsugu Horiuchi
Temporary treatment with AT1 receptor blocker, valsartan, from early stage of hypertension prevented vascular remodeling.
American journal of hypertension 2011;24(5):550-6.
2011: Mie Kurata; Takafumi Okura; Jun Irita; D Enomoto; T Nagao; M Jotoku; Ken-ichi Miyoshi; V R Desilva; Jitsuo Higaki
Angiotensin II receptor blockade with valsartan decreases plasma osteopontin levels in patients with essential hypertension.
Journal of human hypertension 2011;25(5):334-9.
2011: Shinji Inaba; Hideki Okayama; Haruhiko Higashi; Kazuhisa Nishimura; Katsuji Inoue; Akiyoshi Ogimoto; Jitsuo Higaki
Usefulness of transthoracic Doppler echocardiography for noninvasive assessment of coronary blood flow in a patient with symptomatic myocardial bridging.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2011;12(3):E15.
2011: Jitsuo Higaki; Takuya Tsuchihashi; Nobuyuki Ura; Masaaki Miyakawa; Masayoshi Kukida
[Discussion meeting on optimization of antihypertensive treatment in the JSH2009 era].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(2):453-70.
2011: Takafumi Okura; Jitsuo Higaki
[Chronic renal disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(2):385-93.
2011: Makoto Saito; Hideki Okayama; Toyofumi Yoshii; Go Hiasa; Takumi Sumimoto; Shinji Inaba; Kazuhisa Nishimura; Katsuji Inoue; Akiyoshi Ogimoto; Yuji Shigematsu; Jun-ichi Funada; Mareomi Hamada; Jitsuo Higaki
Myocardial fibrosis attenuates the effect of cibenzoline on left ventricular diastolic function in patients with hypertrophic cardiomyopathy.
Journal of cardiovascular pharmacology 2011;57(2):207-12.
2011: Kazuki Ohno; Yasushi Amano; Hirotoshi Kakuta; Tatsuya Niimi; Shoji Takakura; Masaya Orita; Keiji Miyata; Hitoshi Sakashita; Makoto Takeuchi; Issei Komuro; Jitsuo Higaki; Masatsugu Horiuchi; Shokei Kim-Mitsuyama; Yutaka Mori; Ryuichi Morishita; Sho-ichi Yamagishi
Unique "delta lock" structure of telmisartan is involved in its strongest binding affinity to angiotensin II type 1 receptor.
Biochemical and biophysical research communications 2011;404(1):434-7.
2011: Takafumi Okura; Daijiro Enomoto; Jun Irita; Ryoji Ito; Masanori Jotoku; Ken-ichi Miyoshi; Tomoaki Nagao; Jitsuo Higaki
A patient with myeloperoxidase antineutrophil cytoplasmic antibody-positive polyangiitis who developed sensorineural hearing loss and scleritis.
Internal medicine (Tokyo, Japan) 2011;50(16):1725-8.
2011: Yuji Shigematsu; Jitsuo Higaki
[Evidences of ARB interventional studies that prevent the progression of hypertension and hypertensive target organ damage].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 1():597-600.
2011: Kohei Hosokawa; Hiroshi Imagawa; Kanji Kawachi; Teruhito Kido; Tomoyuki Kido; Akira Kurata; Jitsuo Higaki; Hiroshi Higashino; Akiyoshi Ogimoto; Fumiaki Shikata; Teruhito Mochizuki
Transmural perfusion gradient in adenosine triphosphate stress myocardial perfusion computed tomography.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(8):1905-12.
2011: Katsuji Inoue; Kazuhisa Nishimura; Akiyoshi Ogimoto; Hideki Okayama; Makoto Saito; Takumi Sumimoto; Jun Suzuki; Toyofumi Yoshii; Jun-ichi Funada; Go Hiasa; Shinji Inaba; Jitsuo Higaki
Right ventricular septal pacing preserves global left ventricular longitudinal function in comparison with apical pacing: analysis of speckle tracking echocardiography.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(7):1609-15.
2010: Takafumi Okura; Masanori Jotoku; Jun Irita; Daijiro Enomoto; Tomoaki Nagao; Veena Rasika Desilva; Shiho Yamane; Zuowei Pei; Shiho Kojima; Yasuyuki Hamano; Shinichi Mashiba; Mie Kurata; Ken-ichi Miyoshi; Jitsuo Higaki
Association between cystatin C and inflammation in patients with essential hypertension.
Clinical and experimental nephrology 2010;14(6):584-8.
2010: Shinji Inaba; Hideki Okayama; Jun-ichi Funada; Hidetoshi Hashida; Go Hiasa; Takumi Sumimoto; Yasunori Takata; Kazuhisa Nishimura; Katsuji Inoue; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Jitsuo Higaki
Relationship between smaller calcifications and lipid-rich plaques on integrated backscatter-intravascular ultrasound.
International journal of cardiology 2010;145(2):347-8.
2010: Akiyoshi Ogimoto; Jitsuo Higaki
Smoking wears away happiness: new concept, 'smoking creates thunderclouds'.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(11):1104-5.
2010: Shinji Inaba; Takashi Higaki; Mitsugi Nagashima; Kazuhisa Nishimura; Akiyoshi Ogimoto; Jitsuo Higaki; Hideki Okayama
Successful revascularization by pulse infusion thrombolysis in a patient with Kawasaki disease combined with acute myocardial infarction.
JACC. Cardiovascular interventions 2010;3(10):1091-2.
2010: Naohiko Hamaguchi; Hironobu Hamada; Seigo Miyoshi; Kazunori Irifune; Ryoji Ito; Tatsuhiko Miyazaki; Jitsuo Higaki
In vitro and in vivo therapeutic efficacy of the PPAR-γ agonist troglitazone in combination with cisplatin against malignant pleural mesothelioma cell growth.
Cancer science 2010;101(9):1955-64.
2010: Norikatsu Morioka; Jun-ichi Funada; Yasunori Takata; Hidetoshi Hashida; Takeru Iwata; Jitsuo Higaki; Hideki Okayama
Influence of meal intake on pulse wave indices in type 2 diabetes.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(7):743-7.
2010: Takayuki Nagai; Jitsuo Higaki; Hideki Okayama
Cardiovascular flashlight. Atrial tachycardia in congenital left atrial appendage aneurysm: three-dimensional computed tomography imaging with electro-anatomical mapping.
European heart journal 2010;31(13):1590.
2010: Seigo Miyoshi; Hironobu Hamada; Toru Kadowaki; Naohiko Hamaguchi; Ryoji Ito; Kazunori Irifune; Jitsuo Higaki
Comparative evaluation of serum markers in pulmonary sarcoidosis.
Chest 2010;137(6):1391-7.
2010: Akiyoshi Ogimoto; Hideki Okayama; Takayuki Nagai; Tomoaki Ohtsuka; Jun Suzuki; Katsuji Inoue; Kazuhisa Nishimura; Makoto Saito; Yuji Shigematsu; Mareomi Hamada; Tetsuro Miki; Jitsuo Higaki
Pharmacogenetic interactions between Angiotensin-converting enzyme insertion/deletion polymorphism and response to cibenzoline in patients with hypertrophic obstructive cardiomyopathy.
Journal of cardiovascular pharmacology 2010;55(5):506-10.
2010: Jun-ichi Funada; Yasunori Takata; Hidetoshi Hashida; Yuji Matsumoto; Sumiko Sato; Go Hiasa; Katsuji Inoue; Jitsuo Higaki; Hideki Okayama
Dysfunctional central hemodynamic regulation after daily meal intake in metabolic syndrome.
Atherosclerosis 2010;210(1):268-73.
2010: Yuma Inoue; Xiaomei Yang; Michinobu Nagao; Hiroshi Higashino; Kohei Hosokawa; Teruhito Kido; Akira Kurata; Hideki Okayama; Jitsuo Higaki; Teruhito Mochizuki; Kenya Murase
Peri-infarct dysfunction in post-myocardial infarction: assessment of 3-T tagged and late enhancement MRI.
European radiology 2010;20(5):1139-48.
2010: Takafumi Okura; Mie Kurata; Jun Irita; Daijiro Enomoto; Masanori Jotoku; Tomoaki Nagao; Mitsuko Koresawa; Shiho Kojima; Yasuyuki Hamano; Shinichi Mashiba; Ken-Ichi Miyoshi; Jitsuo Higaki
Renal resistance index is a marker of future renal dysfunction in patients with essential hypertension.
Journal of nephrology 2010;23(2):175-80.
2010: Katsuji Inoue; Hideki Okayama; Kazuhisa Nishimura; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Makoto Saito; Go Hiasa; Toyofumi Yoshii; Takumi Sumimoto; Junichi Funada; Jitsuo Higaki
Right ventricular pacing from the septum avoids the acute exacerbation in left ventricular dyssynchrony and torsional behavior seen with pacing from the apex.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2010;23(2):195-200.
2010: Mie Kurata; Takafumi Okura; Jun Irita; Daijiro Enomoto; Tomoaki Nagao; Masanori Jotoku; Ken-ichi Miyoshi; Jitsuo Higaki
The relationship between osteopontin and adiponectin in patients with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2010;32(6):358-63.
2010: Seigo Miyoshi; Hironobu Hamada; Hitoshi Katayama; Naohiko Hamaguchi; Kazunori Irifune; Ryoji Ito; Yuji Ohtsuki; Tadashi Yoshino; Jitsuo Higaki
A case of pulmonary nodular lymphoid hyperplasia with a resected cavity, followed by spontaneous regression of the remaining lesions.
Internal medicine (Tokyo, Japan) 2010;49(15):1617-21.
2010: Takafumi Okura; Mie Kurata; Daijiro Enomoto; Masanori Jotoku; Tomoaki Nagao; Veena Rasika Desilva; Jun Irita; Ken-Ichi Miyoshi; Jitsuo Higaki
Undercarboxylated osteocalcin is a biomarker of carotid calcification in patients with essential hypertension.
Kidney & blood pressure research 2010;33(1):66-71.
2010: Kazuhisa Nishimura; Hideki Okayama; Katsuji Inoue; Makoto Saito; Takayuki Nagai; Jun Suzuki; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Jitsuo Higaki
Visualization of traumatic tricuspid insufficiency by three-dimensional echocardiography.
Journal of cardiology 2010;55(1):143-6.
2010: Hiroshi Matsuoka; Hideo Kawakami; Akira Ohshita; Tamami Kohno; Susumu Shigemi; Hideki Okayama; Jitsuo Higaki
Bare metal stent implantation for in-stent restenosis with a drug-eluting stent.
Journal of cardiology 2010;55(1):135-8.
2010: Takafumi Okura; Jitsuo Higaki
[Calcium antagonists: current and future applications based on new evidence. Calcium channel blockers and single-pill combination].
Clinical calcium 2010;20(1):61-8.
2009: Jitsuo Higaki
The ideal combination of anti-hypertensive drugs.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(12):1059.
2009: Toru Kadowaki; Hironobu Hamada; Ai Fujiwara; Seigo Miyoshi; Naohiko Hamaguchi; Ryoji Ito; Jitsuo Higaki
Bacterial tracheobronchitis. A rare cause of adult airway stenosis.
Respirology (Carlton, Vic.) 2009;14(8):1214-6.
2009: Akiyoshi Ogimoto; Hideki Okayama; Takayuki Nagai; Tomoaki Ohtsuka; Jun Suzuki; Katsuji Inoue; Kazuhisa Nishimura; Yuji Shigematsu; Yasuharu Tabara; Katsuhiko Kohara; Tetsuro Miki; Jitsuo Higaki
Association of monocyte chemoattractant protein 1 gene polymorphism with susceptibility to nonfamilial idiopathic dilated cardiomyopathy.
Journal of cardiology 2009;54(1):66-70.
2009: Yuji Shigematsu; Sadako Norimatsu; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Hideki Okayama; Jitsuo Higaki
The influence of insulin resistance and obesity on left atrial size in Japanese hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(6):500-4.
2009: Takafumi Okura; Jitsuo Higaki; Mie Kurata; Jun Irita; Ken-ichi Miyoshi; Tsutomu Yamazaki; Doubun Hayashi; Takahide Kohro; Ryozo Nagai
Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis: subanalysis of the Japanese Coronary Artery Disease (JCAD) Study.
Circulation journal : official journal of the Japanese Circulation Society 2009;73(5):885-91.
2009: Teruyoshi Uetani; Hironao Nakayama; Hideki Okayama; Takafumi Okura; Jitsuo Higaki; Hirofumi Inoue; Shigeki Higashiyama
Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase.
The Journal of biological chemistry 2009;284(18):12399-409.
2009: Takafumi Okura; Jitsuo Higaki
[Combination therapy of ARB with other class of antihypertensive agents (including fixed combination)].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(4):819-25.
2009: Toshio Ogihara; Takao Saruta; Hiromi Rakugi; Akira Fujimoto; Kenji Ueshima; Shinji Yasuno; Koji Oba; Kazuo Takeda; Jitsuo Higaki; Kazuwa Nakao
Relationship between the achieved blood pressure and the incidence of cardiovascular events in Japanese hypertensive patients with complications: a sub-analysis of the CASE-J trial.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(4):248-54.
2009: Teppei Fujita; Masaki Mogi; Li-Juan Min; Jun Iwanami; Kana Tsukuda; Akiko Sakata; Hideki Okayama; Masaru Iwai; Clara Nahmias; Jitsuo Higaki; Masatsugu Horiuchi
Attenuation of cuff-induced neointimal formation by overexpression of angiotensin II type 2 receptor-interacting protein 1.
Hypertension 2009;53(4):688-93.
2009: Takafumi Okura; Masanori Jotoku; Ken-ichi Miyoshi; Daijiro Enomoto; Mie Kurata; Jun Irita; Tomoaki Nagao; Tomoaki Ohtsuka; Jitsuo Higaki
Case of membranoproliferative glomerulonephritis due to essential cryoglobulinemia without hepatitis C virus infection.
Geriatrics & gerontology international 2009;9(1):92-6.
2009: Toshio Ogihara; Takao Saruta; Hiromi Rakugi; Kazuaki Shimamoto; Sadayoshi Ito; Hiroaki Matsuoka; Masatsugu Horiuchi; Tsutomu Imaizumi; Shuichi Takishita; Jitsuo Higaki; Shigehiro Katayama; Ikuo Saito; Kazuyuki Shimada
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(2):163-7.
2009: Shinji Inaba; Masaru Iwai; Yumiko Tomono; Izumi Senba; Megumi Furuno; Harumi Kanno; Hideki Okayama; Masaki Mogi; Jitsuo Higaki; Masatsugu Horiuchi
Prevention of vascular injury by combination of an AT1 receptor blocker, olmesartan, with various calcium antagonists.
American journal of hypertension 2009;22(2):145-50.
2009: Shinji Inaba; Masaru Iwai; Megumi Furuno; Yumiko Tomono; Harumi Kanno; Izumi Senba; Hideki Okayama; Masaki Mogi; Jitsuo Higaki; Masatsugu Horiuchi
Continuous activation of renin-angiotensin system impairs cognitive function in renin/angiotensinogen transgenic mice.
Hypertension 2009;53(2):356-62.
2009: Shinji Inaba; Masaru Iwai; Yumiko Tomono; Izumi Senba; Megumi Furuno; Harumi Kanno; Hideki Okayama; Masaki Mogi; Jitsuo Higaki; Masatsugu Horiuchi
Exaggeration of focal cerebral ischemia in transgenic mice carrying human Renin and human angiotensinogen genes.
Stroke; a journal of cerebral circulation 2009;40(2):597-603.
2009: M Saito; Hideki Okayama; K Nishimura; Akiyoshi Ogimoto; Tomoaki Ohtsuka; K Inoue; Go Hiasa; T Sumimoto; Jun-ichi Funada; Yuji Shigematsu; Jitsuo Higaki
Determinants of left ventricular untwisting behaviour in patients with dilated cardiomyopathy: analysis by two-dimensional speckle tracking.
Heart (British Cardiac Society) 2009;95(4):290-6.
2009: Makoto Saito; Hideki Okayama; Jitsuo Higaki
Coronary flow dynamics associated with ventricular tachycardia in a patient with hypertrophic cardiomyopathy.
Journal of cardiovascular electrophysiology 2009;20(2):224-5.
2009: Masanori Jotoku; Takafumi Okura; Tomoaki Nagao; Daijiro Enomoto; Jun Irita; Ken-ichi Miyoshi; Mie Kurata; Tomikazu Fukuoka; Jitsuo Higaki
[Case of 131I-meta-iodobenzylguanidine (MIBG) scintigraphy-negative and 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET)-positive pheochromocytoma].
Nihon Jinzo Gakkai shi 2009;51(5):563-8.
2009: Toshio Ogihara; Kenjiro Kikuchi; Hiroaki Matsuoka; Toshiro Fujita; Jitsuo Higaki; Masatsugu Horiuchi; Yutaka Imai; Tsutomu Imaizumi; Sadayoshi Ito; Hiroshi Iwao; Kazuomi Kario; Yuhei Kawano; Shokei Kim-Mitsuyama; Genjiro Kimura; Hiroaki Matsubara; Hideo Matsuura; Mitsuhide Naruse; Ikuo Saito; Kazuyuki Shimada; Kazuaki Shimamoto; Hiromichi Suzuki; Shuichi Takishita; Norio Tanahashi; Takuya Tsuchihashi; Makoto Uchiyama; Shinichiro Ueda; Hirotsugu Ueshima; Satoshi Umemura; Toshihiko Ishimitsu; Hiromi Rakugi
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009).
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(1):3-107.
2009: Takafumi Okura; Ken-ichi Miyoshi; Tomoaki Nagao; Masanori Jotoku; Daijiro Enomoto; Jun Irita; Mie Kurata; Jitsuo Higaki
Light chain deposition disease developing 15 years following the diagnosis of monoclonal gammopathy of undetermined significance.
Internal medicine (Tokyo, Japan) 2009;48(2):101-4.
2009: Takayuki Nagai; Wataru Shimizu; Akiyoshi Ogimoto; Jitsuo Higaki; Hideki Okayama
Ventricular fibrillation induced by a narrow QRS complex tachycardia in a patient with Brugada syndrome.
Journal of cardiovascular electrophysiology 2009;20(1):106-7.
2008: Takafumi Okura; Jitsuo Higaki
[Mild hypertension in middle aged adults].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(8):1481-5.
2008: Takafumi Okura; Sanae Watanabe; Mie Kurata; Mitsuko Koresawa; Jun Irita; Daijiro Enomoto; Masanori Jotoku; Ken-ichi Miyoshi; Tomikazu Fukuoka; Jitsuo Higaki
Long-term effects of angiotensin II receptor blockade with valsartan on carotid arterial stiffness and hemodynamic alterations in patients with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2008;30(5):415-22.
2008: Teruhito Kido; Akira Kurata; Hiroshi Higashino; Yuma Inoue; Rene Epunza Kanza; Hideki Okayama; Jitsuo Higaki; Kenya Murase; Teruhito Mochizuki
Quantification of regional myocardial blood flow using first-pass multidetector-row computed tomography and adenosine triphosphate in coronary artery disease.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(7):1086-91.
2008: M Saito; Hideki Okayama; K Nishimura; Akiyoshi Ogimoto; Tomoaki Ohtsuka; K Inoue; Go Hiasa; T Sumimoto; Jitsuo Higaki
Possible link between large artery stiffness and coronary flow velocity reserve.
Heart (British Cardiac Society) 2008;94(6):e20.
2008: Hideki Okayama; Kazuhisa Nishimura; Makoto Saito; Katsuji Inoue; Go Hiasa; Takumi Sumimoto; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Yuji Shigematsu; Jitsuo Higaki
Significance of the distal to proximal coronary flow velocity ratio by transthoracic Doppler echocardiography for diagnosis of proximal left coronary artery stenosis.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2008;21(6):756-60.
2008: Seigo Miyoshi; Hironobu Hamada; Ryoji Ito; Naohiko Hamaguchi; Toru Kadowaki; Jitsuo Higaki
[Successful treatment of non-small cell lung cancer by gefitinib in an elderly patient with poor performance status].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2008;45(3):338-42.
2008: Takafumi Okura; Jun Irita; Daijiro Enomoto; Seiko Manabe; Mie Kurata; Ken-Ichi Miyoshi; Tomikazu Fukuoka; Jitsuo Higaki
A case of hyperreninemic hypertension with bilateral positive captopril renography but without renovascular stenosis.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(2):383-6.
2008: Yasunori Takata; Haruhiko Osawa; Mie Kurata; Maki Kurokawa; Junko Yamauchi; Masaaki Ochi; Wataru Nishida; Takafumi Okura; Jitsuo Higaki; Hideichi Makino
Hyperresistinemia is associated with coexistence of hypertension and type 2 diabetes.
Hypertension 2008;51(2):534-9.
2008: Jun Irita; Takafumi Okura; Mie Kurata; Ken-ichi Miyoshi; Tomikazu Fukuoka; Jitsuo Higaki
Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone.
Hypertension 2008;51(2):507-13.
2008: Toru Kadowaki; Hironobu Hamada; Seigo Miyoshi; Naohiko Hamaguchi; Kimiko Sakai; Ryoji Ito; Miki Yasutake-Oshima; Jitsuo Higaki; Katsumi Kito
Refractory pneumothorax secondary to lung cancer in a patient with idiopathic pulmonary fibrosis.
Internal medicine (Tokyo, Japan) 2008;47(13):1251-4.
2007: Koji Mitsuiki; Atsumi Harada; Takafumi Okura; Jitsuo Higaki
Histologically advanced IgA nephropathy treated successfully with prednisolone and cyclophosphamide.
Clinical and experimental nephrology 2007;11(4):297-303.
2007: Takayuki Nagai; Akiyoshi Ogimoto; Hideki Okayama; Tomoaki Ohtsuka; Yuji Shigematsu; Mareomi Hamada; Tetsuro Miki; Jitsuo Higaki
A985G polymorphism of the endothelin-2 gene and atrial fibrillation in patients with hypertrophic cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(12):1932-6.
2007: Tomoaki Ohtsuka; Kazuhisa Nishimura; Akira Kurata; Akiyoshi Ogimoto; Hideki Okayama; Jitsuo Higaki
Serum matrix metalloproteinase-3 as a novel marker for risk stratification of patients with nonischemic dilated cardiomyopathy.
Journal of cardiac failure 2007;13(9):752-8.
2007: Yoshiharu Horie; Jitsuo Higaki; Masahiro Takeuchi
Design, statistical analysis and sample size calculation of dose response study of telmisartan and hydrochlorothiazide.
Contemporary clinical trials 2007;28(5):647-53.
2007: Hironobu Hamada; Kazunori Irifune; Ryoji Ito; Kimiko Sakai; Toru Kadowaki; Hitoshi Katayama; Masahiro Abe; Masahiro Shiode; Kazutaka Nishimura; Jitsuo Higaki
Docetaxel and cisplatin as second-line chemotherapy for advanced non-small cell lung cancer.
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(8):1235-9.
2007: Seiko Manabe; Takafumi Okura; Tomikazu Fukuoka; Jitsuo Higaki
Antioxidative effects of azelnidipine on mesangial cell proliferation induced by highly concentrated insulin.
European journal of pharmacology 2007;567(3):252-7.
2007: Hironobu Hamada; Jitsuo Higaki
[Major drug-induced lung diseases: effects of drugs for the circulatory system].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2007;96(6):1109-16.
2007: Takafumi Okura; Jitsuo Higaki
Inhibition of matrix metalloproteinase and hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(6):477-8.
2007: Takafumi Okura; Sanae Watanabe; Mie Kurata; Seiko Manabe; Mitsuko Koresawa; Jun Irita; Daijiro Enomoto; Ken-ichi Miyoshi; Tomikazu Fukuoka; Jitsuo Higaki
Relationship between cardio-ankle vascular index (CAVI) and carotid atherosclerosis in patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(4):335-40.
2007: Toru Kadowaki; Hironobu Hamada; Ryoji Ito; Naohiko Hamaguchi; Kimiko Sakai; Jitsuo Higaki
[Chronic necrotizing pulmonary aspergillosis in the surgically treated lung].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2007;45(4):372-6.
2007: Ken-ichi Miyoshi; Takafumi Okura; Tomikazu Fukuoka; Jitsuo Higaki
CCAAT/enhancer-binding protein-delta is induced in mesangial area during the early stages of anti-Thy1.1 glomerulonephritis and regulates cell proliferation and inflammatory gene expression in cultured rat mesangial cells.
Clinical and experimental nephrology 2007;11(1):26-33.
2007: Takafumi Okura; Jitsuo Higaki
[Etiology of essential hypertension].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2007;96(1):4-8.
2007: Toru Kadowaki; Hironobu Hamada; Akihito Yokoyama; Masahiro Abe; Kazutaka Nishimura; Nobuoki Kohno; Junya Inata; Toshihiko Kuraoka; Chie Moritani; Jitsuo Higaki
Significance of serum uric acid in patients with chronic respiratory failure treated with non-invasive positive pressure ventilation.
Internal medicine (Tokyo, Japan) 2007;46(11):691-7.
2007: Teruhito Kido; Akira Kurata; Hiroshi Higashino; Yoshifumi Sugawara; Hideki Okayama; Jitsuo Higaki; Hirofumi Anno; Kazuhiro Katada; Shinichiro Mori; Shuji Tanada; Masahiro Endo; Teruhito Mochizuki
Cardiac imaging using 256-detector row four-dimensional CT: preliminary clinical report.
Radiation medicine 2007;25(1):38-44.
2006: Jitsuo Higaki
[Antihypertensive therapy in very-old patients].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2006;43(6):697-9.
2006: Mie Kurata; Takafumi Okura; Sanae Watanabe; Tomikazu Fukuoka; Jitsuo Higaki
Osteopontin and carotid atherosclerosis in patients with essential hypertension.
Clinical science (London, England : 1979) 2006;111(5):319-24.
2006: Sanae Watanabe; Takafumi Okura; Mie Kurata; Jun Irita; Seiko Manabe; Ken-ichi Miyoshi; Tomikazu Fukuoka; Kazuo Murakami; Jitsuo Higaki
The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension.
Clinical therapeutics 2006;28(10):1677-85.
2006: Akira Oshita; Masaru Iwai; Rui Chen; Ayumi Ide; Midori Okumura; Shiori Fukunaga; Toyofumi Yoshii; Masaki Mogi; Jitsuo Higaki; Masatsugu Horiuchi
Attenuation of inflammatory vascular remodeling by angiotensin II type 1 receptor-associated protein.
Hypertension 2006;48(4):671-6.
2006: Koichi Moriguchi; Hiromi Rakugi; Shinya Nagata; Ryuji Nagai; Atsushi Moriguchi; Atsunori Okamura; Mitsuru Ohishi; Jitsuo Higaki; Toshio Ogihara
Impairment of instantaneous autonomic regulation relates to blood pressure fall immediately after standing in the elderly and hypertensives.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(8):557-66.
2006: Takafumi Okura; Jitsuo Higaki
[VALUE].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 6():419-24.
2006: Yuji Shigematsu; Sadako Norimatsu; Tomoaki Ohtsuka; Hideki Okayama; Jitsuo Higaki
Sex-related differences in the relations of insulin resistance and obesity to left ventricular hypertrophy in Japanese hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(7):499-504.
2006: Akiyoshi Ogimoto; Jitsuo Higaki
[Guanine nucleotide-binding protein beta 3 subunit (GNB3) gene polymorphism].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():450-4.
2006: Sanae Watanabe; Takafumi Okura; Mie Kurata; Jun Irita; Seiko Manabe; Ken-ichi Miyoshi; Tomikazu Fukuoka; Akiko Gotoh; Kazuo Uchida; Jitsuo Higaki
Valsartan reduces serum cystatin C and the renal vascular resistance in patients with essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2006;28(5):451-61.
2006: Toyofumi Yoshii; Masaru Iwai; Zhen Li; Rui Chen; Ayumi Ide; Shiori Fukunaga; Akira Oshita; Masaki Mogi; Jitsuo Higaki; Masatsugu Horiuchi
Regression of atherosclerosis by amlodipine via anti-inflammatory and anti-oxidative stress actions.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(6):457-66.
2006: Takafumi Okura; Ken-ichi Miyoshi; Sanae Watanabe; Mie Kurata; Jun Irita; Seiko Manabe; Tomikazu Fukuoka; Jitsuo Higaki; Hironobu Sasano
Coexistence of three distinct adrenal tumors in the same adrenal gland in a patient with primary aldosteronism and preclinical Cushing's syndrome.
Clinical and experimental nephrology 2006;10(2):127-30.
2006: Jitsuo Higaki
Arteriosclerosis and C-reactive protein gene.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(5):299.
2006: Toyoaki Haraikawa; Hiroshi Higashino; Yoshifumi Sugawara; Hitoshi Miki; Akira Kurata; Jitsuo Higaki; Teruhito Mochizuki
Assessment of left ventricular wall motion using 16-channel multislice computed tomography: comparison with left ventriculography.
Radiation medicine 2006;24(3):159-64.
2006: Jun Suzuki; Masaru Iwai; Masaki Mogi; Akira Oshita; Toyofumi Yoshii; Jitsuo Higaki; Masatsugu Horiuchi
Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):917-21.
2006: Ryoji Ito; Akihito Yokoyama; Hironobu Hamada; Yoshifumi Yasuhara; Nobuoki Kohno; Jitsuo Higaki
Effect of inhaled bronchodilators on air trapping in patients with stable asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 2006;43(2):125-9.
2006: Jun Irita; Takafumi Okura; Seiko Manabe; Mie Kurata; Ken-ichi Miyoshi; Sanae Watanabe; Tomikazu Fukuoka; Jitsuo Higaki
Plasma osteopontin levels are higher in patients with primary aldosteronism than in patients with essential hypertension.
American journal of hypertension 2006;19(3):293-7.
2006: Jitsuo Higaki
[Increasing menace of cardiovascular diseases in the era of obesity].
Rinsho byori. The Japanese journal of clinical pathology 2006;54(2):170-5.
2006: Hiroshi Higashino; Teruhito Mochizuki; Toyoaki Haraikawa; Akira Kurata; Teruhito Kido; Shigeru Nakata; Yoshifumi Sugawara; Masao Miyagawa; Hitoshi Miki; Yasushi Koyama; Hideki Okayama; Jitsuo Higaki
Image fusion of coronary tree and regional cardiac function image using multislice computed tomography.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(1):105-9.
2005: Seiko Manabe; Takafumi Okura; Sanae Watanabe; Tomikazu Fukuoka; Jitsuo Higaki
Effects of angiotensin II receptor blockade with valsartan on pro-inflammatory cytokines in patients with essential hypertension.
Journal of cardiovascular pharmacology 2005;46(6):735-9.
2005: Toru Kadowaki; Hironobu Hamada; Akihito Yokoyama; Hitoshi Katayama; Takayoshi Aramoto; Norifumi Ueda; Hiromi Tomioka; Jitsuo Higaki
Thymic carcinoma originating from the mid-posterior mediastinum.
Respirology (Carlton, Vic.) 2005;10(5):689-91.
2005: Yasunori Takata; Van Chu; Alan R Collins; Christopher J Lyon; Wei Wang; Florian Blaschke; Dennis Bruemmer; Evren Caglayan; William Daley; Jitsuo Higaki; Michael C Fishbein; Rajendra K Tangirala; Ronald E Law; Willa A Hsueh
Transcriptional repression of ATP-binding cassette transporter A1 gene in macrophages: a novel atherosclerotic effect of angiotensin II.
Circulation research 2005;97(9):e88-96.
2005: Akiyoshi Ogimoto; Yuji Shigematsu; Yuji Hara; Tomoaki Ohtsuka; Tetsuro Miki; Jitsuo Higaki
Black pearl in the LIFE study: angiotensin-II receptor blockade on atrial fibrillation for future personalized medicine.
Journal of the American College of Cardiology 2005;46(8):1585; author reply 1585-6.
2005: Mie Kurata; Takafumi Okura; Sanae Watanabe; Jitsuo Higaki
Association between carotid hemodynamics and asymptomatic white and gray matter lesions in patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(10):797-803.
2005: Seiko Manabe; Takafumi Okura; Sanae Watanabe; Jitsuo Higaki
Association between carotid haemodynamics and inflammation in patients with essential hypertension.
Journal of human hypertension 2005;19(10):787-91.
2005: Aki Kato; Hitoshi Katayama; Hironobu Hamada; Tomoaki Nagao; Toru Kadowaki; Ryoji Ito; Kazunori Irifune; Jitsuo Higaki
[A case of small cell lung cancer with intramedullary spinal cord metastasis].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2005;42(5):567-70.
2005: Tomoaki Nagao; Takafumi Okura; Ken-ichi Miyoshi; Sanae Watanabe; Seiko Manabe; Mie Kurata; Jun Irita; Tomikazu Fukuoka; Jitsuo Higaki
Fibrillary glomerulonephritis associated with monoclonal gammopathy of undetermined significance showing lambda-type Bence Jones protein.
Clinical and experimental nephrology 2005;9(3):247-51.
2005: Mareomi Hamada; Yuji Shigematsu; Shinji Inaba; Jun Aono; Shuntaro Ikeda; Kouki Watanabe; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Yuji Hara; Jitsuo Higaki
Antiarrhythmic drug cibenzoline attenuates left ventricular pressure gradient and improves transmitral Doppler flow pattern in patients with hypertrophic obstructive cardiomyopathy caused by midventricular obstruction.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(8):940-5.
2005: Akiyoshi Ogimoto; Yuji Shigematsu; Jun Nakura; Yuji Hara; Tomoaki Ohtsuka; Katsuhiko Kohara; Mareomi Hamada; Tetsuro Miki; Jitsuo Higaki
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with coexistent hypertrophic cardiomyopathy and coronary spastic angina.
Journal of molecular medicine (Berlin, Germany) 2005;83(8):619-25.
2005: Akiyoshi Ogimoto; Mareomi Hamada; Tetsuro Miki; Jitsuo Higaki
Angiotensin I-converting enzyme insertion/insertion genotype as a genetic risk factor for cardiovascular disease.
American heart journal 2005;150(1):e1; author reply e3.
2005: Toru Kadowaki; Hironobu Hamada; Akihito Yokoyama; Hitoshi Katayama; Masahiro Abe; Kazutaka Nishimura; Noriyuki Tomiyama; Katsumi Kito; Tatsuhiko Miyazaki; Jitsuo Higaki
Two cases of primary pulmonary osteosarcoma.
Internal medicine (Tokyo, Japan) 2005;44(6):632-7.
2005: Jitsuo Higaki
[Future medicine for hypertension in the elderly].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(6):1067-70.
2005: Tomoaki Ohtsuka; Katsuji Inoue; Yuji Hara; Norikatsu Morioka; Kiyotaka Ohshima; Jun Suzuki; Akiyoshi Ogimoto; Yuji Shigematsu; Jitsuo Higaki
Serum markers of angiogenesis and myocardial ultrasonic tissue characterization in patients with dilated cardiomyopathy.
European journal of heart failure 2005;7(4):689-95.
2005: Norikatsu Morioka; Yuji Shigematsu; Mareomi Hamada; Jitsuo Higaki
Circulating levels of heart-type fatty acid-binding protein and its relation to thallium-201 perfusion defects in patients with hypertrophic cardiomyopathy.
The American journal of cardiology 2005;95(11):1334-7.
2005: Yasushi Koyama; Hiroshi Matsuoka; Teruhito Mochizuki; Hiroshi Higashino; Hideo Kawakami; Shigeru Nakata; Jun Aono; Taketoshi Ito; Makiko Naka; Yasuo Ohashi; Jitsuo Higaki
Assessment of reperfused acute myocardial infarction with two-phase contrast-enhanced helical CT: prediction of left ventricular function and wall thickness.
Radiology 2005;235(3):804-11.
2005: Akira Kurata; Teruhito Mochizuki; Yasushi Koyama; Toyoaki Haraikawa; Jun Suzuki; Yuji Shigematsu; Jitsuo Higaki
Myocardial perfusion imaging using adenosine triphosphate stress multi-slice spiral computed tomography: alternative to stress myocardial perfusion scintigraphy.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(5):550-7.
2005: Toru Kadowaki; Hironobu Hamada; Akihito Yokoyama; Ryoji Ito; Sanae Ishimaru; Hiroshi Ohnishi; Hitoshi Katayama; Miki Oshima; Takafumi Okura; Katsumi Kito; Jitsuo Higaki
Hemoperitoneum secondary to spontaneous rupture of hepatic metastasis from lung cancer.
Internal medicine (Tokyo, Japan) 2005;44(4):290-3.
2005: Seigo Miyoshi; Yuji Hara; Yuji Shigenmatsu; Tomoaki Ohtsuka; Akiyoshi Ogimoto; Takafumi Ohkura; Jitsuo Higaki
Separate origins of three coronary arteries arising from the right sinus of Valsalva.
The Canadian journal of cardiology 2005;21(5):451-2.
2005: Yuji Shigematsu; Yuji Hara; Tomoaki Ohtsuka; Akiyoshi Ohgimoto; Katsuji Inoue; Jitsuo Higaki
Relation of genetic predisposition and insulin resistance to left ventricular hypertrophy in hypertension.
American journal of hypertension 2005;18(4 Pt 1):457-63.
2005: Kazunori Irifune; Akihito Yokoyama; Kimiko Sakai; A Watanabe; Hitoshi Katayama; Hiroshi Ohnishi; Hironobu Hamada; M Nakajima; Nobuoki Kohno; Jitsuo Higaki
Adoptive transfer of T-helper cell type 1 clones attenuates an asthmatic phenotype in mice.
The European respiratory journal 2005;25(4):653-9.
2005: Akiyoshi Ogimoto; Yuji Shigematsu; Jitsuo Higaki; Tetsuro Miki
Angiotensin-converting enzyme inhibitors as a new therapy for atrial fibrillation? Controversy.
American heart journal 2005;149(3):566.
2005: Akiyoshi Ogimoto; Jitsuo Higaki
[Genome-wide analysis of single nucleotide polymorphisms].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2005;125(3):148-52.
2005: Sanae Watanabe; Takafumi Okura; Jitsuo Higaki
[11Beta-hydroxylase deficiency].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():288-91.
2005: Takafumi Okura; Jitsuo Higaki
[Atherosclerosis].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 3():161-6.
2005: Akira Kurata; Yuji Shigematsu; Jitsuo Higaki
Sex-related differences in relations of uric acid to left ventricular hypertrophy and remodeling in Japanese hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2005;28(2):133-9.
2005: Ryoji Ito; Hironobu Hamada; Akihito Yokoyama; Miki Oshima; Hitoshi Katayama; Hiroshi Ohnishi; Toru Kadowaki; Sanae Ishimaru; Kazunori Irifune; Jitsuo Higaki
Successful treatment of obstructive sleep apnea syndrome improves autonomic nervous system dysfunction.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2005;27(2-3):259-67.
2005: Hiroshi Imagawa; Kanji Kawachi; Shinji Takano; Nobuo Tsunooka; Fumiaki Shikata; Toyoaki Haraigawa; Satoshi Hosoi; Teruhito Mochizuki; Jitsuo Higaki; Susumu Nakano
Impact of multi-detector row computed tomography on the tactics of cardiovascular surgery: from qualitative evaluation to quantitative assessment.
The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi 2005;53(2):78-83.
2005: Akiyoshi Ogimoto; Takeshi Mizobuchi; Yuji Shigematsu; Yuji Hara; Tomoaki Ohtsuka; Tomikazu Fukuoka; Takafumi Okura; Jitsuo Higaki
Exercise-related syncope induced by vasodilator therapy in an elderly hypertensive patient.
Journal of the American Geriatrics Society 2005;53(2):351-2.
2005: Yuji Hara; Katsuji Inoue; Akiyoshi Ogimoto; Tomoaki Ohtsuka; Yuji Shigematsu; Shigeru Nakata; Jitsuo Higaki
Effect of beta-blocker therapy on myocardial perfusion defects in thallium-201 scintigraphy in patients with dilated cardiomyopathy.
Cardiology 2005;104(1):16-21.
2005: Tamami Kono; Akiyoshi Ogimoto; Yuji Shigematsu; Yuji Hara; Takafumi Okura; Katsuji Inoue; Jitsuo Higaki
[A 73-year-old man with primary pulmonary hypertension].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2005;42(1):116-20.
2005: Seigo Miyoshi; Yuji Hara; Akiyoshi Ogimoto; Yuji Shigematsu; Takafumi Okura; Jitsuo Higaki
[Repeated changes of electrocardiogram caused by Takotsubo-type cardiomyopathy: a case with hypertrophic nonobstructive cardiomyopathy].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2005;42(1):112-5.
2005: Hiroshi Ohnishi; Masahiro Abe; Hironobu Hamada; Akihito Yokoyama; Takeru Hirayama; Ryoji Ito; Kazutaka Nishimura; Jitsuo Higaki
Metastatic renal cell carcinoma presenting as multiple pleural tumours.
Respirology (Carlton, Vic.) 2005;10(1):128-31.
2004: Hitoshi Katayama; Hironobu Hamada; Akihito Yokoyama; Toru Kadowaki; Ryoji Ito; Jitsuo Higaki
[A case of interstitial pneumonia caused by gosha-jinki-gan].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2004;41(6):675-8.
2004: Sanae Ishimaru; Hitoshi Katayama; Hironobu Hamada; Akihito Yokoyama; Toru Kadowaki; Ryoji Ito; Yasuo Iwamoto; Teruomi Miyazawa; Jitsuo Higaki
[A case of primary adenocarcinoma of the trachea].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2004;42(11):966-9.
2004: Akiyoshi Ogimoto; Jitsuo Higaki; Tetsuro Miki
Polymorphism of inhibitory renin-angiotensin system as a genetic risk factor for atrial fibrillation.
Circulation 2004;110(13):e329; author reply e329.
2004: Ken-ichi Miyoshi; Takafumi Okura; Seiko Manabe; Sanae Watanabe; Tomikazu Fukuoka; Jitsuo Higaki
Granulomatous interstitial nephritis due to isolated renal sarcoidosis.
Clinical and experimental nephrology 2004;8(3):279-82.
2004: Florian Blaschke; Dennis Bruemmer; Fen Yin; Yasunori Takata; Wei Wang; Michael C Fishbein; Takafumi Okura; Jitsuo Higaki; Kristof Graf; Eckart Fleck; Willa A Hsueh; Ronald E Law
C-reactive protein induces apoptosis in human coronary vascular smooth muscle cells.
Circulation 2004;110(5):579-87.
2004: Tomoaki Ohtsuka; Mareomi Hamada; Katsuji Inoue; Kiyotaka Ohshima; Jun Sujzuki; Tsuyoshi Matsunaka; Akiyoshi Ogimoto; Yuji Hara; Yuji Shigematsu; Jitsuo Higaki
Relation of circulating interleukin-6 to left ventricular remodeling in patients with reperfused anterior myocardial infarction.
Clinical cardiology 2004;27(7):417-20.
2004: Kazuo Murakami; Yuji Shigematsu; Mareomi Hamada; Jitsuo Higaki
Insulin resistance in patients with hypertrophic cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(7):650-5.
2004: Katsuji Inoue; Mareomi Hamada; Tomoaki Ohtsuka; Yuji Hara; Yuji Shigematsu; Shigeru Nakata; Jitsuo Higaki
Myocardial microvascular abnormalities observed by intravenous myocardial contrast echocardiography in patients with hypertrophic cardiomyopathy.
The American journal of cardiology 2004;94(1):55-8.
2004: Yasushi Koyama; Teruhito Mochizuki; Jitsuo Higaki
Computed tomography assessment of myocardial perfusion, viability, and function.
Journal of magnetic resonance imaging : JMRI 2004;19(6):800-15.
2004: Hiroshi Ohnishi; Masahiro Abe; Akihito Yokoyama; Hironobu Hamada; Ryoji Ito; Takeru Hirayama; Kazutaka Nishimura; Jitsuo Higaki
Clarithromycin-induced eosinophilic pneumonia.
Internal medicine (Tokyo, Japan) 2004;43(3):231-5.
2004: Takafumi Okura; Sanae Watanabe; Ken-ichi Miyoshi; Tomikazu Fukuoka; Jitsuo Higaki
Intrarenal and carotid hemodynamics in patients with essential hypertension.
American journal of hypertension 2004;17(3):240-4.
2004: Kei Kamide; Hiromi Rakugi; Michiko Nagai; Shin Takiuchi; Naomichi Matsukawa; Jitsuo Higaki; Yuhei Kawano; Toshio Ogihara; Michael L Tuck
Insulin-mediated regulation of the endothelial renin-angiotensin system and vascular cell growth.
Journal of hypertension 2004;22(1):121-7.
2004: Akiyoshi Ogimoto; Mareomi Hamada; Yuji Shigematsu; Yuji Hara; Hideyuki Saeki; Hitoshi Katayama; Hironobu Hamada; Jitsuo Higaki
[Cardiac tamponade with paroxysmal atrial flutter controlled by antituberculous therapy].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2004;41(1):112-6.
2004: Katsuji Inoue; Mareomi Hamada; Tomoaki Ohtsuka; Jitsuo Higaki
Relation of myocardial blood volume to left ventricular function and future cardiac events in patients with idiopathic dilated cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(1):53-8.
2003: Tsuguya Fukui; Mahbubur Rahman; Koichi Hayashi; Kazuo Takeda; Jitsuo Higaki; Tosiya Sato; Masanori Fukushima; Junichi Sakamoto; Satoshi Morita; Toshio Ogihara; Kohshiro Fukiyama; Masatoshi Fujishima; Takao Saruta
Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial of cardiovascular events in high-risk hypertensive patients: rationale, design, and methods.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(12):979-90.
2003: Shin Takiuchi; Hiromi Rakugi; Hideki Fujii; Kei Kamide; Takeshi Horio; Satoshi Nakatani; Yuhei Kawano; Jitsuo Higaki; Toshio Ogihara
Carotid intima-media thickness is correlated with impairment of coronary flow reserve in hypertensive patients without coronary artery disease.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(12):945-51.
2003: Sanae Watanabe; Takafumi Okura; Jun Liu; Ken-ichi Miyoshi; Tomikazu Fukuoka; Kunio Hiwada; Jitsuo Higaki
Serum cystatin C level is a marker of end-organ damage in patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(11):895-9.
2003: Yuji Hara; Mareomi Hamada; Yuji Shigematsu; Tomoaki Ohtsuka; Akiyoshi Ogimoto; Jun Suzuki; Jitsuo Higaki
Effect of beta-blocker therapy in elderly patients with dilated cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2003;67(10):826-9.
2003: Hiroshi Ohnishi; Akihito Yokoyama; Yoshifumi Yasuhara; Akira Watanabe; T Naka; Hironobu Hamada; Masahiro Abe; Kazutaka Nishimura; Jitsuo Higaki; Junpei Ikezoe; Nobuoki Kohno
Circulating KL-6 levels in patients with drug induced pneumonitis.
Thorax 2003;58(10):872-5.
2003: Akiyoshi Ogimoto; Mareomi Hamada; Tomoaki Ohtsuka; Yuji Hara; Yuji Shigematsu; Akihito Yokoyama; Hiroshi Imagawa; Kanji Kawachi; Katsumi Kito; Jitsuo Higaki
Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis.
Internal medicine (Tokyo, Japan) 2003;42(9):827-30.
2003: Hitoshi Katayama; Akihito Yokoyama; Hironobu Hamada; Jun Irita; Toru Kadowaki; Ryoji Ito; Hiroshi Onishi; Akira Watanabe; Yasushi Mutsukado; Hitoshi Kukita; Kunio Hiwada; Jitsuo Higaki
[Successful treatment of bronchiolitis obliterans organizing pneumonia with cyclosporin and steroids].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2003;41(8):551-5.
2003: Yuji Hara; Mareomi Hamada; Yuji Shigematsu; Tomoaki Ohtsuka; Akiyoshi Ogimoto; Jitsuo Higaki
Effect of beta-blockers on insulin resistance in patients with dilated cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society 2003;67(8):701-4.
2003: Tsuyoshi Matsunaka; Mareomi Hamada; Yuji Matsumoto; Jitsuo Higaki
First-pass myocardial perfusion defect and delayed contrast enhancement in hypertrophic cardiomyopathy assessed with MRI.
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine 2003;2(2):61-9.
2003: Ryuji Nagai; Shinya Nagata; Fumiyo Fukuya; Jitsuo Higaki; Hiromi Rakugi; Toshio Ogihara
Changes in autonomic activity and baroreflex sensitivity with the hypertension process and age in rats.
Clinical and experimental pharmacology & physiology 2003;30(5-6):419-25.
2003: Jun Suzuki; Jitsuo Higaki; Masatsugu Horiuchi
[Tissue renin-angiotensin system and ischemic heart diseases].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 5():837-42.
2003: Tomoaki Ohtsuka; Mareomi Hamada; Hideyuki Saeki; Akiyoshi Ogimoto; Yuji Hara; Yuji Shigematsu; Jitsuo Higaki
Serum levels of matrix metalloproteinases and tumor necrosis factor-alpha in patients with idiopathic dilated cardiomyopathy and effect of carvedilol on these levels.
The American journal of cardiology 2003;91(8):1024-7, A8.
2003: Keiko Matsumoto; Ryuichi Morishita; Naruya Tomita; Atsushi Moriguchi; Norio Komai; Motokuni Aoki; Kunio Matsumoto; Toshikazu Nakamura; Jitsuo Higaki; Toshio Ogihara
Improvement of endothelial dysfunction by angiotensin II blockade accompanied by induction of vascular hepatocyte growth factor system in diabetic spontaneously hypertensive rats.
Heart and vessels 2003;18(1):18-25.
2003: Michiko Nagai; Kei Kamide; Hiromi Rakugi; Shin Takiuchi; Michio Imai; Iwao Kida; Naomichi Matsukawa; Jitsuo Higaki; Toshio Ogihara
Role of endothelin-1 induced by insulin in the regulation of vascular cell growth.
American journal of hypertension 2003;16(3):223-8.
2002: Hiroshi Ohnishi; Akihito Yokoyama; Hironobu Hamada; Seiko Manabe; Ryoji Ito; Akira Watanabe; Hitoshi Katayama; Yoshifumi Yasuhara; Junpei Ikezoe; Jitsuo Higaki
Humidifier lung: possible contribution of endotoxin-induced lung injury.
Internal medicine (Tokyo, Japan) 2002;41(12):1179-82.
2002: Shin Takiuchi; Hiromi Rakugi; Tohru Masuyama; Hiroshi Ikegami; Tomoko Nishikage; Maki Shintani; Norio Komai; Michiko Nagai; Kei Kamide; Jitsuo Higaki; Toshio Ogihara
Hypertension attenuates the efficacy of hypoglycemic therapy for preserving coronary flow reserve in patients with type 2 diabetes.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(6):893-900.
2002: Tomohiro Katsuya; Shunroku Baba; Kazuhiko Ishikawa; Toshifumi Mannami; Yuxiao Fu; Nozomu Inamoto; Takashi Asai; Masayuki Fukuda; Jitsuo Higaki; Jun Ogata; Toshio Ogihara
Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: the Suita Study.
Journal of hypertension 2002;20(10):2017-21.
2002: Naruya Tomita; Ryuichi Morishita; Kei Yamamoto; Jitsuo Higaki; Victor J Dzau; Toshio Ogihara; Yasufumi Kaneda
Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes.
The journal of gene medicine 2002;4(5):527-35.
2002: Norio Komai; Ryuichi Morishita; Shingo Yamada; Mitsuru Oishi; Sota Iguchi; Motokuni Aoki; Minako Sasaki; Ikunosuke Sakurabayashi; Jitsuo Higaki; Toshio Ogihara
Mitogenic activity of oxidized lipoprotein (a) on human vascular smooth muscle cells.
Hypertension 2002;40(3):310-4.
2002: Ken Sugimoto; Atsushi Hozawa; Tomohiro Katsuya; Mitsunobu Matsubara; Takayoshi Ohkubo; Ichiro Tsuji; Masaharu Motone; Jitsuo Higaki; Shigeru Hisamachi; Yutaka Imai; Toshio Ogihara
alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study.
Journal of hypertension 2002;20(9):1779-84.
2002: Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara
[Examination of genetic susceptibility for essential hypertension].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2002;39(4):378-80.
2002: Tohru Fujiwara; Tomohiro Katsuya; Mitsunobu Matsubara; Tadayoshi Mikami; Kazuhiko Ishikawa; Masahiro Kikuya; Takayoshi Ohkubo; Atsushi Hozawa; Mari Michimata; Michiko Suzuki; Hirohito Metoki; Kei Asayama; Tsutomu Araki; Ichiro Tsuji; Jitsuo Higaki; Hiroshi Satoh; Shigeru Hisamichi; Toshio Ogihara; Yutaka Imai
T+31C polymorphism of angiotensinogen gene and nocturnal blood pressure decline: the Ohasama study.
American journal of hypertension 2002;15(7 Pt 1):628-32.
2002: Norio Komai; Mitsuru Ohishi; Ryuichi Morishita; Atsushi Moriguchi; Masaharu Kaibe; Keiko Matsumoto; Hiromi Rakugi; Jitsuo Higaki; Toshio Ogihara
Serum hepatocyte growth factor concentration is correlated with the forearm vasodilator response in hypertensive patients.
American journal of hypertension 2002;15(6):499-506.
2002: Maki Shintani; Hiroshi Ikegami; Tomomi Fujisawa; Yoshihiko Kawaguchi; Mitsuru Ohishi; Tomohiro Katsuya; Jitsuo Higaki; Kazuaki Shimamoto; Toshio Ogihara
Leptin gene polymorphism is associated with hypertension independent of obesity.
The Journal of clinical endocrinology and metabolism 2002;87(6):2909-12.
2002: Mitsunobu Matsubara; Michiko Suzuki; Tohru Fujiwara; Masahiro Kikuya; Hirohito Metoki; Mari Michimata; Tsutomu Araki; Itsuro Kazama; Tomomi Satoh; Junichiro Hashimoto; Atsushi Hozawa; Takayoshi Ohkubo; Ichiro Tsuji; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara; Hiroshi Satoh; Yutaka Imai
Angiotensin-converting enzyme I/D polymorphism and hypertension: the Ohasama study.
Journal of hypertension 2002;20(6):1121-6.
2002: Tomohiko Okuda; Toshiki Sumiya; Ken-ichi Mizutani; Naomi Tago; Toshiyuki Miyata; Tadashi Tanabe; Hisao Kato; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara; Yasuyuki Tsujita; Naoharu Iwai; Ken-ichi Muzutani; Hiroshi Kato
Analyses of differential gene expression in genetic hypertensive rats by microarray.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(2):249-55.
2002: Masayuki Fukuda; Takayoshi Ohkubo; Tomohiro Katsuya; Atsushi Hozawa; Takashi Asai; Mitsunobu Matsubara; Hirofumi Kitaoka; Ichiro Tsuji; Tsutomu Araki; Hiroshi Satoh; Jitsuo Higaki; Shigeru Hisamichi; Yutaka Imai; Toshio Ogihara
Association of a mast cell chymase gene variant with HDL cholesterol, but not with blood pressure in the Ohasama study.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(2):179-84.
2002: Norio Komai; Mitsuru Ohishi; Atsushi Moriguchi; Yoshihiro Yanagitani; Toyohisa Jinno; Keiko Matsumoto; Tomohiro Katsuya; Hiromi Rakugi; Jitsuo Higaki; Toshio Ogihara
Low-dose doxazosin improved aortic stiffness and endothelial dysfunction as measured by noninvasive evaluation.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(1):5-10.
2002: Ken-ichi Mizutani; Ken Sugimoto; Tomohiko Okuda; Tomohiro Katsuya; Toshiyuki Miyata; Tadashi Tanabe; Jitsuo Higaki; Toshio Ogihara; Yukio Yamori; Yasuyuki Tsujita; Naomi Tago; Naoharu Iwai
Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(1):135-40.
2002: Kei Kamide; Hiromi Rakugi; Jitsuo Higaki; Atsunori Okamura; Michiko Nagai; Kouichi Moriguchi; Mitsuru Ohishi; Noriyuki Satoh; Michael L Tuck; Toshio Ogihara
The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats.
American journal of hypertension 2002;15(1 Pt 1):66-71.
2002: Naoharu Iwai; Tomohiro Katsuya; Toshifumi Mannami; Jitsuo Higaki; Toshio Ogihara; Koichi Kokame; Jun Ogata; Shunroku Baba
Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension.
Circulation 2002;105(1):41-7.
2001: T Asai; T Ohkubo; Tomohiro Katsuya; Jitsuo Higaki; Yuxiao Fu; M Fukuda; A Hozawa; M Matsubara; H Kitaoka; I Tsuji; T Araki; H Satoh; S Hisamichi; Y Imai; Toshio Ogihara
Endothelin-1 gene variant associates with blood pressure in obese Japanese subjects: the Ohasama Study.
Hypertension 2001;38(6):1321-4.
2001: Mitsunobu Matsubara; Masahiro Kikuya; Takayoshi Ohkubo; Hirohito Metoki; F Omori; Tohru Fujiwara; Michiko Suzuki; Mari Michimata; Atsushi Hozawa; Tomohiro Katsuya; Jitsuo Higaki; Ichiro Tsuji; Tsutomu Araki; Toshio Ogihara; Hiroshi Satoh; Shigeru Hisamichi; Kenichi Nagai; H Kitaoka; Yutaka Imai
Aldosterone synthase gene (CYP11B2) C-334T polymorphism, ambulatory blood pressure and nocturnal decline in blood pressure in the general Japanese population: the Ohasama Study.
Journal of hypertension 2001;19(12):2179-84.
2001: Yasuyuki Tsujita; Shunroku Baba; R Yamauchi; Toshifumi Mannami; M Kinoshita; R Yamamoto; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara; J Ogata; Naoharu Iwai
Association analyses between genetic polymorphisms of endothelial nitric oxide synthase gene and hypertension in Japanese: The Suita Study.
Journal of hypertension 2001;19(11):1941-8.
2001: Y Maekawa; K Sugimoto; M Ohishi; A Moriguchi; Hiromi Rakugi; K Iegushi; H Orita; Jitsuo Higaki; Toshio Ogihara
[A case of severe systemic edema in an elderly hypertensive patient with systemic lupus erythematodes during long-term treatment with anti-hypertensive drugs].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2001;38(5):696-9.
2001: Tomohiro Katsuya; Yoshio Iwashima; Ken Sugimoto; Masaharu Motone; Takashi Asai; Masayuki Fukuda; Yuxiao Fu; Y Hatanaka; Mitsuru Ohishi; Hiromi Rakugi; Jitsuo Higaki; Toshio Ogihara
Effects of antihypertensive drugs and gene variants in the renin-angiotensin system.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(4):463-7.
2001: Naruya Tomita; Atsushi Moriguchi; Keita Yamasaki; Yoshiaki Taniyama; Noriko Kotani; Naotaka Hashiya; M Yoshida; M Yao; Jitsuo Higaki; Toshio Ogihara
A family with von Hippel-Lindau disease revealed by pheochromocytoma.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(4):445-50.
2001: N Iwai; Shunroku Baba; Toshifumi Mannami; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara; J Ogata
Association of sodium channel gamma-subunit promoter variant with blood pressure.
Hypertension 2001;38(1):86-9.
2001: Toshifumi Mannami; Tomohiro Katsuya; Shunroku Baba; Nozomu Inamoto; Kazuhiko Ishikawa; Jitsuo Higaki; Toshio Ogihara; Jun Ogata
Low potentiality of angiotensin-converting enzyme gene insertion/deletion polymorphism as a useful predictive marker for carotid atherogenesis in a large general population of a Japanese city: the Suita study.
Stroke; a journal of cerebral circulation 2001;32(6):1250-6.
2001: Yuxiao Fu; Tomohiro Katsuya; Takashi Asai; Masayuki Fukuda; Nozomu Inamoto; Yoshio Iwashima; Ken Sugimoto; Hiromi Rakugi; Jitsuo Higaki; Toshio Ogihara
Lack of correlation between Mbo I restriction fragment length polymorphism of renin gene and essential hypertension in Japanese.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(3):295-8.
2001: Jitsuo Higaki; Tomohiro Katsuya; Toshio Ogihara
[Genetic polymorphisms of the renin-angiotensin system].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(5):847-52.
2001: Atsunori Okamura; Hiromi Rakugi; Mitsuru Ohishi; Yoshihiro Yanagitani; M Shimizu; T Nishii; Yoshiaki Taniyama; T Asai; Shin Takiuchi; Kouichi Moriguchi; M Ohkuro; Norio Komai; K Yamada; Nozomu Inamoto; A Otsuka; Jitsuo Higaki; Toshio Ogihara
Additive effects of nicorandil on coronary blood flow during continuous administration of nitroglycerin.
Journal of the American College of Cardiology 2001;37(3):719-25.
2001: Yasuyuki Tsujita; Naoharu Iwai; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara; S Tamaki; M Kinoshita; Toshifumi Mannami; J Ogata; Shunroku Baba
Lack of association between genetic polymorphism of CYP11B2 and hypertension in Japanese: the Suita Study.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(2):105-9.
2001: Y Fu; Tomohiro Katsuya; Jitsuo Higaki; T Asai; M Fukuda; Shin Takiuchi; Y Hatanaka; Hiromi Rakugi; Toshio Ogihara
A common mutation of low-density lipoprotein receptor gene is associated with essential hypertension among Japanese.
Journal of human hypertension 2001;15(2):125-30.
2001: Jitsuo Higaki; Tomohiro Katsuya; Ryuichi Morishita; Toshio Ogihara
Symposium on the etiology of hypertension--summarizing studies in 20th century. 1. Hypertension and genes.
Internal medicine (Tokyo, Japan) 2001;40(2):144-7.
2001: Kazuhiko Ishikawa; Shunroku Baba; Tomohiro Katsuya; N Iwai; T Asai; M Fukuda; Shin Takiuchi; Yuxiao Fu; Toshifumi Mannami; J Ogata; Jitsuo Higaki; Toshio Ogihara
T+31C polymorphism of angiotensinogen gene and essential hypertension.
Hypertension 2001;37(2):281-5.
2001: Kunihiro Matsumoto; Ryuichi Morishita; Atsushi Moriguchi; Naruya Tomita; Motokuni Aoki; H Sakonjo; K Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Inhibition of neointima by angiotensin-converting enzyme inhibitor in porcine coronary artery balloon-injury model.
Hypertension 2001;37(2):270-4.
2000: Naoyuki Sato; Tomohiro Katsuya; T Nakagawa; Kazuhiko Ishikawa; Yuxiao Fu; T Asai; M Fukuda; F Suzuki; Y Nakamura; Jitsuo Higaki; Toshio Ogihara
Nine polymorphisms of angiotensinogen gene in the susceptibility to essential hypertension.
Life sciences 2000;68(3):259-72.
2000: Hironori Nakagami; Ryuichi Morishita; Kazuhiro Yamamoto; Yoshiaki Taniyama; Motokuni Aoki; S Kim; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Anti-apoptotic action of hepatocyte growth factor through mitogen-activated protein kinase on human aortic endothelial cells.
Journal of hypertension 2000;18(10):1411-20.
2000: Kazuhiro Yamamoto; Ryuichi Morishita; Naruya Tomita; T Shimozato; Hironori Nakagami; A Kikuchi; Motokuni Aoki; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model: potential application of ribozyme strategy to treat cardiovascular disease.
Circulation 2000;102(11):1308-14.
2000: Shin Takiuchi; Hiromi Rakugi; K Honda; Tohru Masuyama; N Hirata; Hiroshi Ito; K Sugimoto; Yoshihiro Yanagitani; Kouichi Moriguchi; Atsunori Okamura; Jitsuo Higaki; Toshio Ogihara
Quantitative ultrasonic tissue characterization can identify high-risk atherosclerotic alteration in human carotid arteries.
Circulation 2000;102(7):766-70.
2000: Naruya Tomita; Ryuichi Morishita; S Tomita; Gary H Gibbons; L Zhang; M Horiuchi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara; Victor J Dzau
Transcription factor decoy for NFkappaB inhibits TNF-alpha-induced cytokine and adhesion molecule expression in vivo.
Gene therapy 2000;7(15):1326-32.
2000: Yoshiaki Taniyama; Ryuichi Morishita; Hironori Nakagami; Atsushi Moriguchi; H Sakonjo; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters.
Circulation 2000;102(2):246-52.
2000: Mitsunobu Matsubara; Takayoshi Ohkubo; Mari Michimata; Atsushi Hozawa; K Ishikawa; Tomohiro Katsuya; Kenichi Nagai; Ichiro Tsuji; Jitsuo Higaki; Tsutomu Araki; Hiroshi Satoh; Shigeru Hisamichi; Sadayoshi Ito; Toshio Ogihara; Yutaka Imai
Japanese individuals do not harbor the T594M mutation but do have the P592S mutation in the C-terminus of the beta-subunit of the epithelial sodium channel: the Ohasama study.
Journal of hypertension 2000;18(7):861-6.
2000: Mitsuru Ohishi; Hiromi Rakugi; T Miki; Tomohiro Katsuya; Atsunori Okamura; K Kamide; Y Nakata; S Takami; Hiroshi Ikegami; Yoshihiro Yanagitani; Y Tabuchi; Y Kumahara; Jitsuo Higaki; Toshio Ogihara
Deletion polymorphism of angiotensin-converting enzyme gene is associated with postprandial hyperglycaemia in individuals undergoing general check-up.
Clinical and experimental pharmacology & physiology 2000;27(7):483-7.
2000: Naruya Tomita; Ryuichi Morishita; H Y Lan; Kazuhiro Yamamoto; M Hashizume; M Notake; K Toyosawa; Buichi Fujitani; W Mu; D J Nikolic-Paterson; R C Atkins; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo administration of a nuclear transcription factor-kappaB decoy suppresses experimental crescentic glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2000;11(7):1244-52.
2000: H Matsushita; Ryuichi Morishita; T Nata; Motokuni Aoki; Hironori Nakagami; Yoshiaki Taniyama; K Yamamoto; Jitsuo Higaki; Kaneda Yasufumi; Toshio Ogihara
Hypoxia-induced endothelial apoptosis through nuclear factor-kappaB (NF-kappaB)-mediated bcl-2 suppression: in vivo evidence of the importance of NF-kappaB in endothelial cell regulation.
Circulation research 2000;86(9):974-81.
2000: Jitsuo Higaki; Shunroku Baba; Tomohiro Katsuya; Naoyuki Sato; K Ishikawa; Toshifumi Mannami; J Ogata; Toshio Ogihara
Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men : the Suita Study.
Circulation 2000;101(17):2060-5.
2000: Ryuichi Morishita; Motokuni Aoki; Shun Nakamura; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
Gene therapy for cardiovascular disease using hepatocyte growth factor.
Annals of the New York Academy of Sciences 2000;902():369-76.
2000: Toshio Ogihara; Tomohiro Katsuya; Jitsuo Higaki
Genetic analysis of essential hypertension in Japanese populations.
Annals of the New York Academy of Sciences 2000;902():8-16.
2000: Tomohiro Katsuya; Naoyuki Sato; Takashi Asai; Masayuki Fukuda; Shin Takiuchi; Yuxiao Fu; Rikinari Hanayama; Atsushi Moriguchi; Hiromi Rakugi; Jitsuo Higaki; Toshio Ogihara
Association of polymorphism in the promoter region of the apolipoprotein E gene with diastolic blood pressure in normotensive Japanese.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(3):271-5.
2000: H Matsushita; Ryuichi Morishita; Motokuni Aoki; Naruya Tomita; Yoshiaki Taniyama; Hironori Nakagami; T Shimozato; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells.
Circulation 2000;101(12):1447-52.
2000: Atsushi Moriguchi; Hironori Nakagami; Noriko Kotani; Jitsuo Higaki; Toshio Ogihara
Contribution of cardiovascular hypersensitivity to orthostatic hypertension and the extreme dipper phenomenon.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(2):119-23.
2000: Motokuni Aoki; Ryuichi Morishita; Yoshiaki Taniyama; Iwao Kida; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.
Gene therapy 2000;7(5):417-27.
2000: Shin Takiuchi; Hiromi Rakugi; Tohru Masuyama; Yoshihiro Yanagitani; Kouichi Moriguchi; Jitsuo Higaki; Toshio Ogihara; T Masuyama
[Clinical implications of ultrasonic tissue characterization for atherosclerotic carotid intima-media].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2000;37(2):137-42.
2000: Kazuhiko Ishikawa; Y Imai; Tomohiro Katsuya; T Ohkubo; I Tsuji; K Nagai; S Takami; Y Nakata; H Satoh; Shigeru Hisamichi; Jitsuo Higaki; Toshio Ogihara
Human G-protein beta3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure.
American journal of hypertension 2000;13(2):140-5.
2000: S Takami; Y Imai; Tomohiro Katsuya; T Ohkubo; I Tsuji; K Nagai; H Satoh; Shigeru Hisamichi; Jitsuo Higaki; Toshio Ogihara
Gene polymorphism of the renin-angiotensin system associates with risk for lacunar infarction. The Ohasama study.
American journal of hypertension 2000;13(2):121-7.
2000: Jitsuo Higaki; M Aoki; Ryuichi Morishita; Iwao Kida; Y Taniyama; Naruya Tomita; K Yamamoto; Atsushi Moriguchi; Yasufumi Kaneda; Toshio Ogihara
In vivo evidence of the importance of cardiac angiotensin-converting enzyme in the pathogenesis of cardiac hypertrophy.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):428-34.
2000: Naruya Tomita; Ryuichi Morishita; Jitsuo Higaki; Toshio Ogihara
Novel molecular therapeutic approach to cardiovascular disease based on hepatocyte growth factor.
Journal of atherosclerosis and thrombosis 2000;7(1):1-7.
2000: Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara
[Angiotensin II type 1 receptor gene].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():514-8.
2000: Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara
[Genetics of essential hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():497-501.
2000: Kei Kamide; Jitsuo Higaki; Toshio Ogihara
[Insulin].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():98-102.
2000: Jitsuo Higaki; Toshio Ogihara
[Regulation of the circulation system].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():13-8.
2000: Seiji Hayashi; Ryuichi Morishita; H Matsushita; Hironori Nakagami; Yoshiaki Taniyama; Tadashi Nakamura; Motokuni Aoki; Kazuhiro Yamamoto; Jitsuo Higaki; Toshio Ogihara
Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21.
Hypertension 2000;35(1 Pt 2):237-43.
1999: Seiji Hayashi; Ryuichi Morishita; Shun Nakamura; Kazuhiro Yamamoto; Atsushi Moriguchi; T Nagano; Mutsuo Taiji; H Noguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells.
Circulation 1999;100(19 Suppl):II301-8.
1999: Atsunori Okamura; Mitsuru Ohishi; Hiromi Rakugi; Tomohiro Katsuya; Yoshihiro Yanagitani; Shin Takiuchi; Yoshiaki Taniyama; Kouichi Moriguchi; Hiroshi Ito; Yorihiko Higashino; Kenshi Fujii; Jitsuo Higaki; Toshio Ogihara
Pharmacogenetic analysis of the effect of angiotensin-converting enzyme inhibitor on restenosis after percutaneous transluminal coronary angioplasty.
Angiology 1999;50(10):811-22.
1999: Ryuichi Morishita; Atsushi Moriguchi; Jitsuo Higaki; Toshio Ogihara
Hepatocyte growth factor (HGF) as a potential index of severity of hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(3):161-7.
1999: T Nishii; A Moriguchi; Ryuichi Morishita; K Yamada; S Nakamura; N Tomita; Yasufumi Kaneda; A Fukamizu; H Mikami; Jitsuo Higaki; Toshio Ogihara
Angiotensinogen gene-activating elements regulate blood pressure in the brain.
Circulation research 1999;85(3):257-63.
1999: Tomohiro Katsuya; Jitsuo Higaki; Kazuhiko Ishikawa; Naoyuki Sato; Toshio Ogihara
[Genetic analysis of candidate gene polymorphisms in elderly hypertension].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1999;36(8):547-52.
1999: Shun Nakamura; Atsushi Moriguchi; Ryuichi Morishita; K Yamada; T Nishii; Naruya Tomita; Mitsuru Ohishi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats.
Hypertension 1999;34(2):302-8.
1999: Kunihiro Matsumoto; Ryuichi Morishita; Atsushi Moriguchi; Naruya Tomita; Yoshikage Yo; T Nishii; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats.
Hypertension 1999;34(2):279-84.
1999: Motokuni Aoki; Ryuichi Morishita; H Matsushita; Seiji Hayashi; Hironori Nakagami; Kazuhiro Yamamoto; Atsushi Moriguchi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth.
Hypertension 1999;34(2):192-200.
1999: Ryuichi Morishita; Shun Nakamura; Seiji Hayashi; Yoshiaki Taniyama; Atsushi Moriguchi; T Nagano; Mutsuo Taiji; H Noguchi; S Takeshita; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy.
Hypertension 1999;33(6):1379-84.
1999: Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara
[Gene loci and polymorphisms of angiotensin II receptor].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(5):1020-7.
1999: Mitsuru Ohishi; M Ueda; Hiromi Rakugi; T Naruko; A Kojima; Atsunori Okamura; Jitsuo Higaki; Toshio Ogihara
Relative localization of angiotensin-converting enzyme, chymase and angiotensin II in human coronary atherosclerotic lesions.
Journal of hypertension 1999;17(4):547-53.
1999: Atsunori Okamura; Hiromi Rakugi; Mitsuru Ohishi; Yoshihiro Yanagitani; Shin Takiuchi; Kouichi Moriguchi; P A Fennessy; Jitsuo Higaki; Toshio Ogihara
Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages.
Journal of hypertension 1999;17(4):537-45.
1999: N Okuda; K Kohara; H Mikami; A Moriguchi; K Yamada; Jitsuo Higaki; Toshio Ogihara
Effect of propranolol on central neurotransmitter release in Wistar rats analysed by brain microdialysis.
Clinical and experimental pharmacology & physiology 1999;26(3):220-4.
1999: Yoshihiro Yanagitani; Hiromi Rakugi; Atsunori Okamura; Kouichi Moriguchi; Shin Takiuchi; Mitsuru Ohishi; Keiichiro Suzuki; Jitsuo Higaki; Toshio Ogihara
Angiotensin II type 1 receptor-mediated peroxide production in human macrophages.
Hypertension 1999;33(1 Pt 2):335-9.
1998: Shun Nakamura; Ryuichi Morishita; Atsushi Moriguchi; Yoshikage Yo; Y Nakamura; Seiji Hayashi; Kunihiro Matsumoto; K Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Hepatocyte growth factor as a potential index of complication in diabetes mellitus.
Journal of hypertension 1998;16(12 Pt 2):2019-26.
1998: Ryuichi Morishita; Shingo Yamada; Kazuhiro Yamamoto; Naruya Tomita; Iwao Kida; Ikunosuke Sakurabayashi; A Kikuchi; Yasufumi Kaneda; R Lawn; Jitsuo Higaki; Toshio Ogihara
Novel therapeutic strategy for atherosclerosis: ribozyme oligonucleotides against apolipoprotein(a) selectively inhibit apolipoprotein(a) but not plasminogen gene expression.
Circulation 1998;98(18):1898-904.
1998: Hiromi Rakugi; Y Nakamura; Mitsuru Ohishi; Atsunori Okamura; Yoshihiro Yanagitani; Jitsuo Higaki; Toshio Ogihara
[Vascular endothelial cells and renin-angiotensin system].
Rinsho byori. The Japanese journal of clinical pathology 1998;46(11):1135-41.
1998: Yoshikage Yo; Ryuichi Morishita; Shun Nakamura; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of hepatocyte growth factor in the maintenance of renal structure: anti-apoptotic action of HGF on epithelial cells.
Kidney international 1998;54(4):1128-38.
1998: N Nakano; Ryuichi Morishita; Atsushi Moriguchi; Y Nakamura; Seiji Hayashi; Motokuni Aoki; Iwao Kida; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Negative regulation of local hepatocyte growth factor expression by angiotensin II and transforming growth factor-beta in blood vessels: potential role of HGF in cardiovascular disease.
Hypertension 1998;32(3):444-51.
1998: Ryuichi Morishita; Kazuhiro Yamamoto; Shingo Yamada; H Matsushita; Naruya Tomita; Ikunosuke Sakurabayashi; Yasufumi Kaneda; Atsushi Moriguchi; Jitsuo Higaki; Toshio Ogihara
Stimulatory effect of lipoprotein (a) on proliferation of human mesangial cells: role of lipoprotein (a) in renal disease.
Biochemical and biophysical research communications 1998;249(2):313-20.
1998: Ryuichi Morishita; Shingo Yamada; Jitsuo Higaki; Naruya Tomita; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; Seiji Hayashi; Ikunosuke Sakurabayashi; Yasufumi Kaneda; Toshio Ogihara
Conditioned medium from HepG2 cells transfected with human apolipoprotein(a) gene stimulates growth of human vascular smooth muscle cells: effects of overexpression of human apolipoprotein(a) gene.
Hypertension 1998;32(2):215-22.
1998: Y Nakata; Tomohiro Katsuya; S Takami; Naoyuki Sato; Y Fu; Kazuhiko Ishikawa; Shin Takiuchi; Hiromi Rakugi; T Miki; Jitsuo Higaki; Toshio Ogihara
Methylenetetrahydrofolate reductase gene polymorphism: relation to blood pressure and cerebrovascular disease.
American journal of hypertension 1998;11(8 Pt 1):1019-23.
1998: Naruya Tomita; Ryuichi Morishita; S Tomita; Kazuhiro Yamamoto; Motokuni Aoki; H Matsushita; Seiji Hayashi; Jitsuo Higaki; Toshio Ogihara
Transcription factor decoy for nuclear factor-kappaB inhibits tumor necrosis factor-alpha-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells.
Journal of hypertension 1998;16(7):993-1000.
1998: H Bai; Ryuichi Morishita; Iwao Kida; T Yamakawa; W Zhang; Motokuni Aoki; H Matsushita; A Noda; R Nagai; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara; Yoshiki Sawa; Hikaru Matsuda
Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene.
Gene therapy 1998;5(6):761-9.
1998: Ryuichi Morishita; Jitsuo Higaki; N Tomita; Toshio Ogihara
Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease.
Circulation research 1998;82(10):1023-8.
1998: Kazuhiko Ishikawa; Tomohiro Katsuya; Naoyuki Sato; Y Nakata; S Takami; Shin Takiuchi; Y Fu; Jitsuo Higaki; Toshio Ogihara
No association between alpha-adducin 460 polymorphism and essential hypertension in a Japanese population.
American journal of hypertension 1998;11(4 Pt 1):502-6.
1998: Mitsuru Ohishi; M Ueda; Hiromi Rakugi; Atsunori Okamura; T Naruko; A E Becker; Kunio Hiwada; Akihito Kamitani; K Kamide; Jitsuo Higaki; Toshio Ogihara
[Upregulation of angiotensin-converting enzyme during the healing process after injury at the site of percutaneous transluminal coronary angioplasty in humans].
Journal of cardiology 1998;31(3):185-6.
1998: S Takami; Tomohiro Katsuya; Hiromi Rakugi; Naoyuki Sato; Y Nakata; Akihito Kamitani; T Miki; Jitsuo Higaki; Toshio Ogihara
Angiotensin II type 1 receptor gene polymorphism is associated with increase of left ventricular mass but not with hypertension.
American journal of hypertension 1998;11(3 Pt 1):316-21.
1998: Shun Nakamura; Atsushi Moriguchi; Ryuichi Morishita; Motokuni Aoki; Yoshikage Yo; Seiji Hayashi; N Nakano; Tomohiro Katsuya; S Nakata; S Takami; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
A novel vascular modulator, hepatocyte growth factor (HGF), as a potential index of the severity of hypertension.
Biochemical and biophysical research communications 1998;242(1):238-43.
1998: Ryuichi Morishita; Shun Nakamura; Seiji Hayashi; Motokuni Aoki; H Matsushita; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; Jitsuo Higaki; Toshio Ogihara
Contribution of a vascular modulator, hepatocyte growth factor (HGF), to the pathogenesis of cardiovascular disease.
Journal of atherosclerosis and thrombosis 1998;4(3):128-34.
1998: H Matsushita; Ryuichi Morishita; Iwao Kida; Motokuni Aoki; Seiji Hayashi; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; A Noda; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Inhibition of growth of human vascular smooth muscle cells by overexpression of p21 gene through induction of apoptosis.
Hypertension 1998;31(1 Pt 2):493-8.
1998: Yoshikage Yo; Ryuichi Morishita; Kazuhiro Yamamoto; Naruya Tomita; Iwao Kida; Seiji Hayashi; Atsushi Moriguchi; S Kato; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Actions of hepatocyte growth factor as a local modulator in the kidney: potential role in pathogenesis of renal disease.
Kidney international 1998;53(1):50-8.
1998: D N Zhu; A Moriguchi; H Mikami; Jitsuo Higaki; Toshio Ogihara
Central amino acids mediate cardiovascular response to angiotensin II in the rat.
Brain research bulletin 1998;45(2):189-97.
1997: Y Nakata; Tomohiro Katsuya; Hiromi Rakugi; S Takami; Naoyuki Sato; Kei Kamide; Mitsuru Ohishi; T Miki; Jitsuo Higaki; Toshio Ogihara
Polymorphism of angiotensin converting enzyme, angiotensinogen, and apolipoprotein E genes in a Japanese population with cerebrovascular disease.
American journal of hypertension 1997;10(12 Pt 1):1391-5.
1997: N Nakano; Atsushi Moriguchi; Ryuichi Morishita; Iwao Kida; Naruya Tomita; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats.
Hypertension 1997;30(6):1448-54.
1997: Mitsuru Ohishi; M Ueda; Hiromi Rakugi; Atsunori Okamura; T Naruko; A E Becker; Kunio Hiwada; Akihito Kamitani; K Kamide; Jitsuo Higaki; Toshio Ogihara
Upregulation of angiotensin-converting enzyme during the healing process after injury at the site of percutaneous transluminal coronary angioplasty in humans.
Circulation 1997;96(10):3328-37.
1997: Kei Kamide; Hiromi Rakugi; N Nakano; Mitsuru Ohishi; Y Nakata; S Takami; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara
Insulin resistance is related to silent cerebral infarction in patients with essential hypertension.
American journal of hypertension 1997;10(11):1245-9.
1997: Mitsuru Ohishi; M Ueda; Hiromi Rakugi; T Naruko; A Kojima; Atsunori Okamura; Jitsuo Higaki; Toshio Ogihara
Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans.
Journal of hypertension 1997;15(11):1295-302.
1997: Naoyuki Sato; Tomohiro Katsuya; Hiromi Rakugi; S Takami; Y Nakata; T Miki; Jitsuo Higaki; Toshio Ogihara
Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese.
Hypertension 1997;30(3 Pt 1):321-5.
1997: Ryuichi Morishita; Jitsuo Higaki; Seiji Hayashi; Yoshikage Yo; Motokuni Aoki; Shun Nakamura; Atsushi Moriguchi; H Matsushita; Kunihiro Matsumoto; Tadashi Nakamura; Toshio Ogihara
Role of hepatocyte growth factor in endothelial regulation: prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor.
Diabetologia 1997;40(9):1053-61.
1997: GQ Shen; Hiroshi Ikegami; Tomomi Fujisawa; Yoshinosuke Hamada; Kei Kamide; Hiromi Rakugi; Jitsuo Higaki; H Murakami; Kazuaki Shimamoto; Toshio Ogihara
Asp905Tyr polymorphism of protein phosphatase 1 G subunit gene in hypertension.
Hypertension 1997;30(2 Pt 1):236-9.
1997: Ryuichi Morishita; T Sugimoto; Motokuni Aoki; Iwao Kida; Naruya Tomita; Atsushi Moriguchi; K Maeda; Yoshiki Sawa; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction.
Nature medicine 1997;3(8):894-9.
1997: Kei Kamide; Hiromi Rakugi; M Nagano; N Nakano; Mitsuru Ohishi; Jitsuo Higaki; Toshio Ogihara
Influence of aging on progression of cardiovascular complications associated with insulin resistance in patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 1997;20(2):127-32.
1997: Motokuni Aoki; Ryuichi Morishita; A Muraishi; Atsushi Moriguchi; T Sugimoto; K Maeda; Victor J Dzau; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (Hemagglutinating Virus of Japan)--liposome method.
Journal of molecular and cellular cardiology 1997;29(3):949-59.
1997: Hiromi Rakugi; Atsunori Okamura; Kei Kamide; Mitsuru Ohishi; H Sasamura; Ryuichi Morishita; Jitsuo Higaki; Toshio Ogihara
Recognition of tissue- and subtype-specific modulation of angiotensin II receptors using antibodies against AT1 and AT2 receptors.
Hypertension research : official journal of the Japanese Society of Hypertension 1997;20(1):51-5.
1997: Motokuni Aoki; Ryuichi Morishita; Jitsuo Higaki; Atsushi Moriguchi; Iwao Kida; Seiji Hayashi; H Matsushita; Yasufumi Kaneda; Toshio Ogihara
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method.
Biochemical and biophysical research communications 1997;231(3):540-5.
1997: Motokuni Aoki; Ryuichi Morishita; Jitsuo Higaki; Atsushi Moriguchi; Seiji Hayashi; H Matsushita; Iwao Kida; Naruya Tomita; Yoshiki Sawa; Yasufumi Kaneda; Toshio Ogihara
Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area.
Gene therapy 1997;4(2):120-7.
1997: Ryuichi Morishita; Motokuni Aoki; Shun Nakamura; H Matsushita; Naruya Tomita; Seiji Hayashi; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of a novel vascular modulator, hepatocyte growth factor (HGF), in cardiovascular disease: characterization and regulation of local HGF system.
Journal of atherosclerosis and thrombosis 1997;4(1):12-9.
1997: Motokuni Aoki; Ryuichi Morishita; H Matsushita; N Nakano; S Hayashi; Naruya Tomita; K Yamamoto; Atsushi Moriguchi; Jitsuo Higaki; Toshio Ogihara
Serum deprivation-induced apoptosis accompanied by up-regulation of p53 and bax in human aortic vascular smooth muscle cells.
Heart and vessels 1997;Suppl 12():71-5.
1997: Yoshikage Yo; Atsushi Moriguchi; Jitsuo Higaki; M Nagano; N Nakano; Kei Kamide; H Yu; H Mikami; Toshio Ogihara
Renal effects of an angiotensin II antagonist in stroke-prone spontaneously hypertensive rat.
Nephron 1997;76(4):466-71.
1997: Tomomi Fujisawa; Hiroshi Ikegami; Eiji Yamato; Y Hamada; Kei Kamide; Hiromi Rakugi; Jitsuo Higaki; H Murakami; Kazuaki Shimamoto; Toshio Ogihara
Trp64Arg mutation of beta3-adrenergic receptor in essential hypertension: insulin resistance and the adrenergic system.
American journal of hypertension 1997;10(1):101-5.
1997: Ryuichi Morishita; Shun Nakamura; Y Nakamura; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; Yoshikage Yo; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of an endothelium-specific growth factor, hepatocyte growth factor, on endothelial damage in diabetes.
Diabetes 1997;46(1):138-42.
1996: Kei Kamide; M Nagano; N Nakano; Yoshikage Yo; R Kobayashi; Hiromi Rakugi; Jitsuo Higaki; Toshio Ogihara
Insulin resistance and cardiovascular complications in patients with essential hypertension.
American journal of hypertension 1996;9(12 Pt 1):1165-71.
1996: K Yamada; Atsushi Moriguchi; Ryuichi Morishita; Motokuni Aoki; Y Nakamura; Hiroshi Mikami; T Oshima; M Ninomiya; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system.
The American journal of physiology 1996;271(5 Pt 2):R1212-20.
1996: Seiji Hayashi; Ryuichi Morishita; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; M Nakajima; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid.
Gene therapy 1996;3(10):878-85.
1996: K Iiyama; M Nagano; Yoshikage Yo; N Nagano; Kei Kamide; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Impaired endothelial function with essential hypertension assessed by ultrasonography.
American heart journal 1996;132(4):779-82.
1996: Y Nakamura; Ryuichi Morishita; Jitsuo Higaki; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; K Yamada; Seiji Hayashi; Yoshikage Yo; H Nakano; K Matsumoto; Tadashi Nakamura; Toshio Ogihara
Hepatocyte growth factor is a novel member of the endothelium-specific growth factors: additive stimulatory effect of hepatocyte growth factor with basic fibroblast growth factor but not with vascular endothelial growth factor.
Journal of hypertension 1996;14(9):1067-72.
1996: Y Nakamura; Ryuichi Morishita; Shun Nakamura; Motokuni Aoki; Atsushi Moriguchi; K Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
A vascular modulator, hepatocyte growth factor, is associated with systolic pressure.
Hypertension 1996;28(3):409-13.
1996: Yoshikage Yo; M Nagano; Atsushi Moriguchi; F Nakamura; R Kobayashi; N Okuda; Akihito Kamitani; Y Nakamura; Kei Kamide; Tomomi Fujisawa; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Predominance of nocturnal sympathetic nervous activity in salt-sensitive normotensive subjects.
American journal of hypertension 1996;9(8):726-31.
1996: N Tomita; Ryuichi Morishita; Jitsuo Higaki; S Tomita; Motokuni Aoki; Yasufumi Kaneda; Toshio Ogihara
Sustained transgene expression by transfection of renin gene into liver of neonates.
Biochemical and biophysical research communications 1996;224(1):43-9.
1996: Hiromi Rakugi; H Yu; Akihito Kamitani; Y Nakamura; Mitsuru Ohishi; Kei Kamide; Y Nakata; S Takami; Jitsuo Higaki; Toshio Ogihara
Links between hypertension and myocardial infarction.
American heart journal 1996;132(1 Pt 2 Su):213-21.
1996: Hiroshi Ikegami; Eiji Yamato; Tomomi Fujisawa; Yoshinosuke Hamada; Y Fujioka; Hiromi Rakugi; Jitsuo Higaki; H Murakami; K Shimamoto; Toshio Ogihara
Analysis of candidate genes for insulin resistance in essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 1996;19 Suppl 1():S31-4.
1996: N Tomita; Ryuichi Morishita; Jitsuo Higaki; S Tomita; Motokuni Aoki; Toshio Ogihara; Yasufumi Kaneda
In vivo gene transfer of insulin gene into neonatal rats by the HVJ-liposome method resulted in sustained transgene expression.
Gene therapy 1996;3(6):477-82.
1996: Y Nakata; Tomohiro Katsuya; Hiromi Rakugi; S Takami; Mitsuru Ohishi; K Kamino; Jitsuo Higaki; Y Tabuchi; Y Kumahara; T Miki; Toshio Ogihara
Polymorphism of the apolipoprotein E and angiotensin-converting enzyme genes in Japanese subjects with silent myocardial ischemia.
Hypertension 1996;27(6):1205-9.
1996: Seiji Hayashi; Ryuichi Morishita; Jitsuo Higaki; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; S Yoshiki; K Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells.
Biochemical and biophysical research communications 1996;220(3):539-45.
1996: Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara
[Bartter syndrome].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(3):801-6.
1996: S Takami; Jitsuo Higaki; T Miki; Tomohiro Katsuya; Y Nakata; Hiromi Rakugi; T Serikawa; Toshio Ogihara
Analysis and comparison of new candidate loci for hypertension between genetic hypertensive rat strains.
Hypertension research : official journal of the Japanese Society of Hypertension 1996;19(1):51-6.
1996: Ryuichi Morishita; Jitsuo Higaki; N Tomita; Motokuni Aoki; Atsushi Moriguchi; K Tamura; K Murakami; Yasufumi Kaneda; Toshio Ogihara
Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation.
Hypertension 1996;27(3 Pt 2):502-7.
1996: Ryuichi Morishita; Jitsuo Higaki; M Aoki; S Hayashi; Iwao Kida; Yasufumi Kaneda; Toshio Ogihara
Novel strategy of gene therapy in cardiovascular disease with HVJ-liposome method.
Contributions to nephrology 1996;118():254-64.
1995: N Tomita; Ryuichi Morishita; Jitsuo Higaki; S Tomita; Motokuni Aoki; Yasufumi Kaneda; Toshio Ogihara
Effect of angiotensinogen on blood pressure regulation in normotensive rats: application of a loss of function approach.
Journal of hypertension 1995;13(12 Pt 2):1767-74.
1995: K Yamada; Atsushi Moriguchi; Hiroshi Mikami; N Okuda; Jitsuo Higaki; Toshio Ogihara
The effect of central amino acid neurotransmitters on the antihypertensive response to angiotensin blockade in spontaneous hypertension.
Journal of hypertension 1995;13(12 Pt 2):1624-30.
1995: Y Nakamura; Ryuichi Morishita; Jitsuo Higaki; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; K Yamada; Seiji Hayashi; Yoshikage Yo; K Matsumoto
Expression of local hepatocyte growth factor system in vascular tissues.
Biochemical and biophysical research communications 1995;215(2):483-8.
1995: Toshio Ogihara; M Nagano; Jitsuo Higaki; K Kohara; Hiroshi Mikami
Persistent inhibition of the pressor and aldosterone responses to angiotensin-II by TCV-116 in normotensive subjects.
Journal of cardiovascular pharmacology 1995;26(3):490-4.
1995: Ryuichi Morishita; Jitsuo Higaki; Y Nakamura; M Aoki; K Yamada; Atsushi Moriguchi; Hiromi Rakugi; N Tomita; S Tomita; H Yu
Effect of an antihypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 1995;22(9):665-9.
1995: Tomomi Fujisawa; Hiroshi Ikegami; GQ Shen; Eiji Yamato; K Takekawa; Youji Nakagawa; Yoshinosuke Hamada; H Ueda; Hiromi Rakugi; Jitsuo Higaki
Angiotensin I-converting enzyme gene polymorphism is associated with myocardial infarction, but not with retinopathy or nephropathy, in NIDDM.
Diabetes care 1995;18(7):983-5.
1995: N Tomita; R Morishita; Jitsuo Higaki; M Aoki; Y Nakamura; Hiroshi Mikami; A Fukamizu; K Murakami; Y Kaneda; T Ogihara
Transient decrease in high blood pressure by in vivo transfer of antisense oligodeoxynucleotides against rat angiotensinogen.
Hypertension 1995;26(1):131-6.
1995: Akihito Kamitani; Hiromi Rakugi; Jitsuo Higaki; Mitsuru Ohishi; S J Shi; S Takami; Y Nakata; Yorihiko Higashino; K Fujii; Hiroshi Mikami
Enhanced predictability of myocardial infarction in Japanese by combined genotype analysis.
Hypertension 1995;25(5):950-3.
1995: Tomohiro Katsuya; S Takami; Jitsuo Higaki; T Serikawa; Hiroshi Mikami; T Miki; Toshio Ogihara
Gap junction protein locus on chromosome 18 cosegregates with body weight in the spontaneously hypertensive rat.
Hypertension research : official journal of the Japanese Society of Hypertension 1995;18(1):63-7.
1994: F Nakamura; M Nagano; R Kobayashi; Jitsuo Higaki; Hiroshi Mikami; N Kawaguchi; S Onishi; Toshio Ogihara
Chronic administration of angiotensin II receptor antagonist, TCV-116, in cardiomyopathic hamsters.
The American journal of physiology 1994;267(6 Pt 2):H2297-304.
1994: S J Shi; Hiromi Rakugi; K Higashimori; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Augmentation of angiotensin II release from isolated mesenteric arteries of Wistar-Kyoto and spontaneously hypertensive rats following nephrectomy.
Clinical and experimental pharmacology & physiology 1994;21(10):767-73.
1994: Shigeto Morimoto; E Koh; Keisuke Fukuo; Jitsuo Higaki; Hiroshi Ikegami; T Miki; T Hata; Toshio Ogihara
Long-term effects of pravastatin on serum lipid levels in elderly patients with hypercholesterolemia.
Clinical therapeutics 1994;16(5):793-803.
1994: S J Shi; Hiromi Rakugi; K Higashimori; B B Jiang; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Augmentation by converting enzyme inhibition of accelerated endothelin release from rat mesenteric arteries following nephrectomy.
Biochemical and biophysical research communications 1994;202(1):246-51.
1994: Akihito Kamitani; Hiromi Rakugi; Jitsuo Higaki; Z Yi; Hiroshi Mikami; T Miki; Toshio Ogihara
Association analysis of a polymorphism of the angiotensinogen gene with essential hypertension in Japanese.
Journal of human hypertension 1994;8(7):521-4.
1994: N Nagano; M Nagano; Yoshikage Yo; K Iiyama; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Role of glucose intolerance in cardiac diastolic function in essential hypertension.
Hypertension 1994;23(6 Pt 2):1002-5.
1994: K Iiyama; M Nagano; N Nagano; Yoshikage Yo; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
[Risk factors related to the wall thickness of carotid artery assessed by ultrasonography].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1994;31(4):303-9.
1994: Akihito Kamitani; K Higashimori; K Kohara; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
The effects of central administration of angiotensin II type-1 receptor antagonist, CV-11974, in nephrectomized spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 1994;21(4):271-6.
1994: Yoshikage Yo; M Nagano; N Nagano; K Iiyama; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Effects of age and hypertension on autonomic nervous regulation during passive head-up tilt.
Hypertension 1994;23(1 Suppl):I82-6.
1994: Toshio Ogihara; M Nagano; Hiroshi Mikami; Jitsuo Higaki; K Kohara; J Azuma; T Aoki; Y Hamanaka
Effects of the angiotensin II receptor antagonist, TCV-116, on blood pressure and the renin-angiotensin system in healthy subjects.
Clinical therapeutics 1994;16(1):74-86.
1994: S J Shi; Hiromi Rakugi; K Higashimori; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Activated angiotensin II generation and regulation in rat mesenteric arteries following nephrectomy.
Blood pressure. Supplement 1994;5():27-31.
1994: M Nagano; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Role of the renin-angiotensin system in hypertension in the elderly.
Blood pressure. Supplement 1994;5():130-3.
1994: N Tomita; Jitsuo Higaki; Toshio Ogihara; T Kondo; Yasufumi Kaneda
A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes.
Cancer detection and prevention 1994;18(6):485-91.
1993: H Yu; Hiromi Rakugi; Jitsuo Higaki; Ryuichi Morishita; Hiroshi Mikami; Toshio Ogihara
The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats.
Journal of hypertension 1993;11(12):1347-55.
1993: N Tomita; Jitsuo Higaki; Yasufumi Kaneda; H Yu; Ryuichi Morishita; Hiroshi Mikami; Toshio Ogihara
Hypertensive rats produced by in vivo introduction of the human renin gene.
Circulation research 1993;73(5):898-905.
1993: K Kohara; Hiroshi Mikami; N Okuda; Jitsuo Higaki; Toshio Ogihara
Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat.
Hypertension 1993;21(6 Pt 2):975-9.
1993: R Kobayashi; M Nagano; F Nakamura; Jitsuo Higaki; Y Fujioka; Hiroshi Ikegami; Hiroshi Mikami; N Kawaguchi; S Onishi; Toshio Ogihara
Role of angiotensin II in high fructose-induced left ventricular hypertrophy in rats.
Hypertension 1993;21(6 Pt 2):1051-5.
1993: Toshio Ogihara; M Nagano; Jitsuo Higaki; K Higashimori; Kazuko Masuo; Hiroshi Mikami
Antihypertensive efficacy of FK906, a novel human renin inhibitor.
Clinical therapeutics 1993;15(3):539-48.
1993: N Matsukawa; Yasuki Nonaka; Jitsuo Higaki; M Nagano; Hiroshi Mikami; Toshio Ogihara; M Okamoto
Dahl's salt-resistant normotensive rat has mutations in cytochrome P450(11 beta), but the salt-sensitive hypertensive rat does not.
The Journal of biological chemistry 1993;268(12):9117-21.
1993: Tomohiro Katsuya; Jitsuo Higaki; Y Zhao; T Miki; Hiroshi Mikami; T Serikawa; Toshio Ogihara
A neuropeptide Y locus on chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat.
Biochemical and biophysical research communications 1993;192(1):261-7.
1993: K Higashimori; Y Zhao; Jitsuo Higaki; Akihito Kamitani; Tomohiro Katsuya; J Nakura; T Miki; Hiroshi Mikami; Toshio Ogihara
Association analysis of a polymorphism of the angiotensin converting enzyme gene with essential hypertension in the Japanese population.
Biochemical and biophysical research communications 1993;191(2):399-404.
1993: F Nakamura; M Nagano; Jitsuo Higaki; K Higashimori; Ryuichi Morishita; Hiroshi Mikami; Toshio Ogihara
The angiotensin-converting enzyme inhibitor, perindopril, prevents cardiac hypertrophy in low-renin hypertensive rats.
Clinical and experimental pharmacology & physiology 1993;20(3):135-40.
1993: Ryuichi Morishita; Jitsuo Higaki; H Okunishi; F Nakamura; M Nagano; Hiroshi Mikami; K Ishii; M Miyazaki; Toshio Ogihara
Role of tissue renin angiotensin system in two-kidney, one-clip hypertensive rats.
The American journal of physiology 1993;264(3 Pt 2):F510-4.
1993: Ryuichi Morishita; Jitsuo Higaki; M Nagano; F Nakamura; N Tomita; Y Zhao; Hiroshi Mikami; M Miyazaki; Toshio Ogihara
Discrepancy between renin mRNA and plasma renin level in angiotensin-converting enzyme inhibitor-treated rats.
Clinical and experimental pharmacology & physiology 1993;20(1):15-20.
1993: Jitsuo Higaki; Toshio Ogihara
[Congenital adrenal hypoplasia].
Ryōikibetsu shōkōgun shirīzu 1993;(1):489-91.
1992: Jitsuo Higaki; Toshio Ogihara
[Renin gene analysis of familial Bartter's syndrome].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(12):3106-9.
1992: N Tomita; Jitsuo Higaki; Yasufumi Kaneda; Toshio Ogihara
[Direct in vivo gene introduction into rat kidney].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(12):2874-8.
1992: Tomohiro Katsuya; Jitsuo Higaki; T Miki; K Kohara; H Yagisawa; H Tanase; Hiroshi Mikami; T Serikawa; Hiroshi Nojima; Toshio Ogihara
Hypotensive effect associated with a phospholipase C-delta 1 gene mutation in the spontaneously hypertensive rat.
Biochemical and biophysical research communications 1992;187(3):1359-66.
1992: N Tomita; Jitsuo Higaki; Ryuichi Morishita; K Kato; Hiroshi Mikami; Yasufumi Kaneda; Toshio Ogihara
Direct in vivo gene introduction into rat kidney.
Biochemical and biophysical research communications 1992;186(1):129-34.
1992: M Nagano; Jitsuo Higaki; F Nakamura; K Higashimori; N Nagano; Hiroshi Mikami; Toshio Ogihara
Role of cardiac angiotensin II in isoproterenol-induced left ventricular hypertrophy.
Hypertension 1992;19(6 Pt 2):708-12.
1992: Jitsuo Higaki; Toshio Ogihara
[Pituitary hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():655-61.
1992: Ryuichi Morishita; Jitsuo Higaki; M Miyazaki; Toshio Ogihara
Possible role of the vascular renin-angiotensin system in hypertension and vascular hypertrophy.
Hypertension 1992;19(2 Suppl):II62-7.
1992: M Ohishi; S Kitano; Jitsuo Higaki; Shigeto Morimoto; Hiroshi Ikegami; H Tanabe; Toshio Ogihara
[A case of late-onset Pick's disease with polyuria].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1992;29(2):135-9.
1992: Ryuichi Morishita; Jitsuo Higaki; Hiroshi Mikami; N Matsukawa; Toshio Ogihara
Effect of aging on the renin angiotensin system in patients with renovascular hypertension.
Methods and findings in experimental and clinical pharmacology 1992;14(1):17-21.
1992: K Higashimori; Jitsuo Higaki; T Miki; Akihito Kamitani; Hiroshi Mikami; Y Kumahara; Toshio Ogihara
Analysis of the apolipoprotein B3' hypervariable region in patients with essential hypertension.
Clinical and experimental pharmacology & physiology. Supplement 1992;20():21-3.
1992: Ryuichi Morishita; Jitsuo Higaki; F Nakamura; N Tomita; H Yu; M Nagano; Hiroshi Mikami; Toshio Ogihara
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat.
Blood pressure. Supplement 1992;3():41-7.
1991: F Nakamura; M Nagano; Jitsuo Higaki; K Higashimori; K Katahira; Ryuichi Morishita; Hiroshi Mikami; Toshio Ogihara
Regression of left ventricular hypertrophy by angiotensin converting enzyme inhibitor in reduced renal mass hypertensive rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S398-9.
1991: M Nagano; Jitsuo Higaki; Hiroshi Mikami; M Nakamaru; K Higashimori; K Katahira; Y Tabuchi; Atsushi Moriguchi; F Nakamura; Toshio Ogihara
Converting enzyme inhibitors regressed cardiac hypertrophy and reduced tissue angiotensin II in spontaneously hypertensive rats.
Journal of hypertension 1991;9(7):595-9.
1991: Jitsuo Higaki; A Miya; T Miki; Ryuichi Morishita; Hiroshi Mikami; Shin-ichiro Takai; Toshio Ogihara
Contribution of the activation of the ras oncogene to the evolution of aldosterone- and renin-secreting tumors.
Journal of hypertension 1991;9(2):135-7.
1990: H Tsuchiya; A Otsuka; Hiroshi Mikami; K Katahira; T Tsunetoshi; K Kohara; Jitsuo Higaki; C A Nugent; Toshio Ogihara
Increased atrial natriuretic factor secretion after endothelin injection in dogs.
Methods and findings in experimental and clinical pharmacology 1990;12(6):379-83.
1990: N Matsukawa; Yasuki Nonaka; Z Ying; Jitsuo Higaki; Toshio Ogihara; M Okamoto
Molecular cloning and expression of cDNAS encoding rat aldosterone synthase: variants of cytochrome P-450(11 beta).
Biochemical and biophysical research communications 1990;169(1):245-52.
1990: Ryuichi Morishita; Jitsuo Higaki; Hiroshi Mikami; Toshio Ogihara
Effect of cyclosporin A on aldosterone production by dispersed rabbit adreno-capsular cells.
Life sciences 1990;46(26):1985-9.
1989: Jitsuo Higaki; M Okuno; M Nakamaru; Ryuichi Morishita; S Himeno; Toshio Ogihara
Changes in plasma active renin and prorenin after endoscopic retrograde pancreatography.
Methods and findings in experimental and clinical pharmacology 1989;11(11):703-5.
1989: Jitsuo Higaki; Toshio Ogihara; M Ogawa
Proteolytic activation of aldosterone biosynthesis in rabbit adrenal capsular cells by alpha-chymotrypsin.
Methods and findings in experimental and clinical pharmacology 1989;11(9):555-8.
1989: Ryuichi Morishita; Jitsuo Higaki; Toshio Ogihara
Endothelin stimulates aldosterone biosynthesis by dispersed rabbit adreno-capsular cells.
Biochemical and biophysical research communications 1989;160(2):628-32.
1989: Jitsuo Higaki; Ryuichi Morishita; Toshio Ogihara
Measurements of enzyme activity and immunoreactivity of plasma renin. Limitations of the conventional method for assay of plasma renin catalytic activity.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie 1989;27(4):201-4.
1988: Jitsuo Higaki; Toshio Ogihara; Y Kumahara
Effects of frusemide and captopril on the relationship between biologically and immunologically active renin in human plasma.
Clinical science (London, England : 1979) 1988;75(6):669-72.
1988: Hiromi Rakugi; M Nakamaru; H Saito; Jitsuo Higaki; Toshio Ogihara
Endothelin inhibits renin release from isolated rat glomeruli.
Biochemical and biophysical research communications 1988;155(3):1244-7.