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James Higginbotham

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Michelle Demory Beckler; Jeffrey L Franklin; Patrick J Halvey; Amy-Joan Ham; James N Higginbotham; Imade E Imasuen; Ming Li; Daniel C Liebler; Corbin Whitwell; Robert J Coffey
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
David A Shifrin; Robert J Coffey; James N Higginbotham; Russell E McConnell; Rajalakshmi Nambiar; Matthew J Tyska
Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions.
Anne E Powell; Nripesh Prasad; Yu Shyr; Yang Wang; Mary K Washington; Bruce J Aronow; Jeffrey L Franklin; Yan Guo; Kevin M Haigis; James N Higginbotham; Alwin Juchheim; Shawn E Levy; Yina Li; Anna L Means; Emily J Poulin; Robert J Coffey
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor.

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2013: Michelle Demory Beckler; Jeffrey L Franklin; Patrick J Halvey; Amy-Joan Ham; James N Higginbotham; Imade E Imasuen; Ming Li; Daniel C Liebler; Corbin Whitwell; Robert J Coffey
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Molecular & cellular proteomics : MCP 2013;12(2):343-55.
2012: David A Shifrin; Robert J Coffey; James N Higginbotham; Russell E McConnell; Rajalakshmi Nambiar; Matthew J Tyska
Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions.
Current biology : CB 2012;22(7):627-31.
2012: Anne E Powell; Nripesh Prasad; Yu Shyr; Yang Wang; Mary K Washington; Bruce J Aronow; Jeffrey L Franklin; Yan Guo; Kevin M Haigis; James N Higginbotham; Alwin Juchheim; Shawn E Levy; Yina Li; Anna L Means; Emily J Poulin; Robert J Coffey
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor.
Cell 2012;149(1):146-58.
2011: James N Higginbotham; Michelle Demory Beckler; Jonathan D Gephart; Jeffrey L Franklin; Galina Bogatcheva; Gert-Jan Kremers; David W Piston; Gregory D Ayers; Russell E McConnell; Matthew J Tyska; Robert J Coffey
Amphiregulin exosomes increase cancer cell invasion.
Current biology : CB 2011;21(9):779-86.
2008: Cuixia Tian; Grace K Luskin; Kevin M Dischert; James N Higginbotham; Bryan E Shepherd; James Crowe
Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3279-88.
2007: Sean M Hartig; Rachel R Greene; Gianluca Carlesso; James N Higginbotham; Wasif Khan; Ales Prokop; Jeffrey M Davidson
Kinetic analysis of nanoparticulate polyelectrolyte complex interactions with endothelial cells.
Biomaterials 2007;28(26):3843-55.
2007: Martin L Moore; Michael H Chi; Weisong Zhou; Kasia Goleniewska; Jamye F O'Neal; James N Higginbotham; R Stokes Peebles
Cutting Edge: Oseltamivir decreases T cell GM1 expression and inhibits clearance of respiratory syncytial virus: potential role of endogenous sialidase in antiviral immunity.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2651-4.
2007: Cuixia Tian; Grace K Luskin; Kevin M Dischert; James N Higginbotham; Bryan E Shepherd; James Crowe
Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells.
Molecular immunology 2007;44(9):2173-83.
2006: Cuixia Tian; Grace K Kron; Kevin M Dischert; James N Higginbotham; James Crowe
Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells.
Immunology 2006;119(1):54-62.
2006: Edna F Choo; Daniel Kurnik; Mordechai Muszkat; Tadashi Ohkubo; Sheila D Shay; James N Higginbotham; Hartmut Glaeser; Richard B Kim; Alastair J J Wood; Grant R Wilkinson
Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1012-8.