Stephen High

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Physiology

Phenomena

Concepts & Ideas

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Ray-Sinha Arpita; Cross Benedict C S; Mironov Aleksandr; Wiertz Emmanuel; High Stephen
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein.
Roboti Peristera; Swanton Eileithyia; High Stephen
Differences in endoplasmic-reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein.
Rabu Catherine; Schmid Volker; Schwappach Blanche; High Stephen
Biogenesis of tail-anchored proteins: the beginning for the end?

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Stephen High (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Ray-Sinha Arpita; Cross Benedict C S; Mironov Aleksandr; Wiertz Emmanuel; High Stephen
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein.
Molecular membrane biology 2009;26(8):448-64.
2009: Roboti Peristera; Swanton Eileithyia; High Stephen
Differences in endoplasmic-reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein.
Journal of cell science 2009;122(Pt 21):3942-53.
2009: Rabu Catherine; Schmid Volker; Schwappach Blanche; High Stephen
Biogenesis of tail-anchored proteins: the beginning for the end?
Journal of cell science 2009;122(Pt 20):3605-12.
2009: Cross Benedict C S; High Stephen
Dissecting the physiological role of selective transmembrane-segment retention at the ER translocon.
Journal of cell science 2009;122(Pt 11):1768-77.
2009: Cross Benedict C S; Sinning Irmgard; Luirink Joen; High Stephen
Delivering proteins for export from the cytosol.
Nature reviews. Molecular cell biology 2009;10(4):255-64.
2008: Rabu Catherine; Wipf Peter; Brodsky Jeffrey L; High Stephen
A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum.
The Journal of biological chemistry 2008;283(41):27504-13.
2008: Wilson Cornelia M; Roebuck Quentin; High Stephen
Ribophorin I regulates substrate delivery to the oligosaccharyltransferase core.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9534-9.
2008: Ismail Nurzian; Crawshaw Samuel G; Cross Benedict C S; Haagsma Anna C; High Stephen
Specific transmembrane segments are selectively delayed at the ER translocon during opsin biogenesis.
The Biochemical journal 2008;411(3):495-506.
2007: Rabu Catherine; High Stephen
Membrane protein chaperones: a new twist in the tail?
Current biology : CB 2007;17(12):R472-4.
2007: Abell Benjamin M; Rabu Catherine; Leznicki Pawel; Young Jason C; High Stephen
Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones.
Journal of cell science 2007;120(Pt 10):1743-51.
2007: Crawshaw Samuel G; Cross Benedict C S; Wilson Cornelia M; High Stephen
The oligomeric state of Derlin-1 is modulated by endoplasmic reticulum stress.
Molecular membrane biology 2007;24(2):113-20.
2007: Wilson Cornelia M; High Stephen
Ribophorin I acts as a substrate-specific facilitator of N-glycosylation.
Journal of cell science 2007;120(Pt 4):648-57.
2007: Callan Anna C; Bunning Sandra; Jones Owen T; High Stephen; Swanton Eileithyia
Biosynthesis of the dystonia-associated AAA+ ATPase torsinA at the endoplasmic reticulum.
The Biochemical journal 2007;401(2):607-12.
2006: Swanton Eileithyia; High Stephen
ER targeting signals: more than meets the eye?
Cell 2006;127(5):877-9.
2006: Young Andrew R J; Chan Edmond Y W; Hu Xiao Wen; Köchl Robert; Crawshaw Samuel G; High Stephen; Hailey Dale W; Lippincott-Schwartz Jennifer; Tooze Sharon A
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes.
Journal of cell science 2006;119(Pt 18):3888-900.
2006: Ismail Nurzian; Crawshaw Samuel G; High Stephen
Active and passive displacement of transmembrane domains both occur during opsin biogenesis at the Sec61 translocon.
Journal of cell science 2006;119(Pt 13):2826-36.
2005: Swanton Eileithyia; Holland Andrew; High Stephen; Woodman Philip
Disease-associated mutations cause premature oligomerization of myelin proteolipid protein in the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4342-7.
2005: Lord J Michael; High Stephen
Polytopic proteins: preventing aggregation in the membrane.
Current biology : CB 2005;15(5):R169-71.
2005: Wilson Cornelia M; Kraft Claudine; Duggan Claire; Ismail Nurzian; Crawshaw Samuel G; High Stephen
Ribophorin I associates with a subset of membrane proteins after their integration at the sec61 translocon.
The Journal of biological chemistry 2005;280(6):4195-206.
2004: High S; Abell B M
Tail-anchored protein biosynthesis at the endoplasmic reticulum: the same but different.
Biochemical Society transactions 2004;32(Pt 5):659-62.
2004: Crawshaw Samuel G; Martoglio Bruno; Meacock Suzanna L; High Stephen
A misassembled transmembrane domain of a polytopic protein associates with signal peptide peptidase.
The Biochemical journal 2004;384(Pt 1):9-17.
2004: Abell Benjamin M; Pool Martin R; Schlenker Oliver; Sinning Irmgard; High Stephen
Signal recognition particle mediates post-translational targeting in eukaryotes.
The EMBO journal 2004;23(14):2755-64.
2004: Russell Sarah J; Ruddock Lloyd W; Salo Kirsi E H; Oliver Jason D; Roebuck Quentin P; Llewellyn David H; Roderick H Llewelyn; Koivunen Peppi; Myllyharju Johanna; High Stephen
The primary substrate binding site in the b' domain of ERp57 is adapted for endoplasmic reticulum lectin association.
The Journal of biological chemistry 2004;279(18):18861-9.
2003: Lecomte F J L; Ismail N; High S
Making membrane proteins at the mammalian endoplasmic reticulum.
Biochemical Society transactions 2003;31(Pt 6):1248-52.
2003: Swanton Eileithyia; High Stephen; Woodman Philip
Role of calnexin in the glycan-independent quality control of proteolipid protein.
The EMBO journal 2003;22(12):2948-58.
2003: Abell Benjamin M; Jung Martin; Oliver Jason D; Knight Bruce C; Tyedmers Jens; Zimmermann Richard; High Stephen
Tail-anchored and signal-anchored proteins utilize overlapping pathways during membrane insertion.
The Journal of biological chemistry 2003;278(8):5669-78.
2002: Meacock Suzanna L; Lecomte Fabienne J L; Crawshaw Samuel G; High Stephen
Different transmembrane domains associate with distinct endoplasmic reticulum components during membrane integration of a polytopic protein.
Molecular biology of the cell 2002;13(12):4114-29.
2002: Abell Ben M; High Stephen; Moloney Maurice M
Membrane protein topology of oleosin is constrained by its long hydrophobic domain.
The Journal of biological chemistry 2002;277(10):8602-10.
2001: Spurway T D; Dalley J A; High S; Bulleid N J
Early events in glycosylphosphatidylinositol anchor addition. substrate proteins associate with the transamidase subunit gpi8p.
The Journal of biological chemistry 2001;276(19):15975-82.
2000: High S; Lecomte F J; Russell S J; Abell B M; Oliver J D
Glycoprotein folding in the endoplasmic reticulum: a tale of three chaperones?
FEBS letters 2000;476(1-2):38-41.
2000: Swanton E; Bishop N; Sheehan J; High S; Woodman P
Disassembly of membrane-associated NSF 20S complexes is slow relative to vesicle fusion and is Ca(2+)-independent.
Journal of cell science 2000;113 ( Pt 10)():1783-91.
2000: Meacock S L; Greenfield J J; High S
Protein targeting and translocation at the endoplasmic reticulum membrane--through the eye of a needle?
Essays in biochemistry 2000;36():1-13.
1999: High S; Greenfield J J; Meacock S L; Oliver J D
Membrane-protein biosynthesis at the endoplasmic reticulum.
Biochemical Society transactions 1999;27(6):883-8.
1999: Oliver J D; Roderick H L; Llewellyn D H; High S
ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.
Molecular biology of the cell 1999;10(8):2573-82.
1999: Greenfield J J; High S
The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment.
Journal of cell science 1999;112 ( Pt 10)():1477-86.
1998: Van der Wal F J; Oliver J D; High S
The transient association of ERp57 with N-glycosylated proteins is regulated by glucose trimming.
European journal of biochemistry / FEBS 1998;256(1):51-9.
1998: Swanton E; Sheehan J; Bishop N; High S; Woodman P
Formation and turnover of NSF- and SNAP-containing "fusion" complexes occur on undocked, clathrin-coated vesicle-derived membranes.
Molecular biology of the cell 1998;9(7):1633-47.
1998: Valent Q A; Scotti P A; High S; de Gier J W; von Heijne G; Lentzen G; Wintermeyer W; Oudega B; Luirink J
The Escherichia coli SRP and SecB targeting pathways converge at the translocon.
The EMBO journal 1998;17(9):2504-12.
1998: Knight B C; High S
Membrane integration of Sec61alpha: a core component of the endoplasmic reticulum translocation complex.
The Biochemical journal 1998;331 ( Pt 1)():161-7.
1998: Elliott J G; Oliver J D; Volkmer J; Zimmermann R; High S
In vitro characterisation of the interaction between newly synthesised proteins and a pancreatic isoform of protein disulphide isomerase.
European journal of biochemistry / FEBS 1998;252(3):372-7.
1997: Elliott J G; Oliver J D; High S
The thiol-dependent reductase ERp57 interacts specifically with N-glycosylated integral membrane proteins.
The Journal of biological chemistry 1997;272(21):13849-55.
1997: High S; Henry R; Mould R M; Valent Q; Meacock S; Cline K; Gray J C; Luirink J
Chloroplast SRP54 interacts with a specific subset of thylakoid precursor proteins.
The Journal of biological chemistry 1997;272(17):11622-8.
1997: Laird V; High S
Discrete cross-linking products identified during membrane protein biosynthesis.
The Journal of biological chemistry 1997;272(3):1983-9.
1997: Oliver J D; van der Wal F J; Bulleid N J; High S
Interaction of the thiol-dependent reductase ERp57 with nascent glycoproteins.
Science (New York, N.Y.) 1997;275(5296):86-8.
1996: Oliver J D; Hresko R C; Mueckler M; High S
The glut 1 glucose transporter interacts with calnexin and calreticulin.
The Journal of biological chemistry 1996;271(23):13691-6.
1995: Valent Q A; Kendall D A; High S; Kusters R; Oudega B; Luirink J
Early events in preprotein recognition in E. coli: interaction of SRP and trigger factor with nascent polypeptides.
The EMBO journal 1995;14(22):5494-505.
1995: Wilson R; Allen A J; Oliver J; Brookman J L; High S; Bulleid N J
The translocation, folding, assembly and redox-dependent degradation of secretory and membrane proteins in semi-permeabilized mammalian cells.
The Biochemical journal 1995;307 ( Pt 3)():679-87.
1995: Oliver J; Jungnickel B; Görlich D; Rapoport T; High S
The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum.
FEBS letters 1995;362(2):126-30.
1995: High S
Protein translocation at the membrane of the endoplasmic reticulum.
Progress in biophysics and molecular biology 1995;63(2):233-50.
1994: Luirink J; ten Hagen-Jongman C M; van der Weijden C C; Oudega B; High S; Dobberstein B; Kusters R
An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY.
The EMBO journal 1994;13(10):2289-96.
1993: High S; Martoglio B; Görlich D; Andersen S S; Ashford A J; Giner A; Hartmann E; Prehn S; Rapoport T A; Dobberstein B
Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence.
The Journal of biological chemistry 1993;268(35):26745-51.
1993: High S; Stirling C J
Protein translocation across membranes: common themes in divergent organisms.
Trends in cell biology 1993;3(10):335-9.
1993: High S; Andersen S S; Görlich D; Hartmann E; Prehn S; Rapoport T A; Dobberstein B
Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion.
The Journal of cell biology 1993;121(4):743-50.
1992: Luirink J; High S; Wood H; Giner A; Tollervey D; Dobberstein B
Signal-sequence recognition by an Escherichia coli ribonucleoprotein complex.
Nature 1992;359(6397):741-3.
1992: High S; Dobberstein B
Mechanisms that determine the transmembrane disposition of proteins.
Current opinion in cell biology 1992;4(4):581-6.
1992: High S
Membrane protein insertion into the endoplasmic reticulum--another channel tunnel?
BioEssays : news and reviews in molecular, cellular and developmental biology 1992;14(8):535-40.
1992: Lütcke H; High S; Römisch K; Ashford A J; Dobberstein B
The methionine-rich domain of the 54 kDa subunit of signal recognition particle is sufficient for the interaction with signal sequences.
The EMBO journal 1992;11(4):1543-51.
1991: High S; Dobberstein B
The signal sequence interacts with the methionine-rich domain of the 54-kD protein of signal recognition particle.
The Journal of cell biology 1991;113(2):229-33.
1991: High S; Görlich D; Wiedmann M; Rapoport T A; Dobberstein B
The identification of proteins in the proximity of signal-anchor sequences during their targeting to and insertion into the membrane of the ER.
The Journal of cell biology 1991;113(1):35-44.
1991: High S; Flint N; Dobberstein B
Requirements for the membrane insertion of signal-anchor type proteins.
The Journal of cell biology 1991;113(1):25-34.
1990: Römisch K; Ribes V; High S; Lütcke H; Tollervey D; Dobberstein B
Structure and function of signal recognition particle (SRP).
Molecular biology reports 1990;14(2-3):71-2.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Stephen High

Research Profile (preview)

Anatomy

Chemicals & Drugs

Physiology

Phenomena

Concepts & Ideas

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Stephen High (preview)

All Publications