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Itsuro Higuchi

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Chihiro Yonee; Sarah P Young; Itsuro Higuchi; Yoshihiro Maegaki; Shinsuke Maruyama; Eiji Nanba; Aya Narita; Kousaku Ohno; Mitsuo Toyoshima; Yoshifumi Kawano
Quantitative computed tomography for enzyme replacement therapy in Pompe disease.
Yukie Inamori; Teruhiko Inoue; Yoshio Mitsuyama; Ryuichi Okubo; Yusuke Sakiyama; Tadafumi Shiraishi; Kimiyoshi Arimura; Akihiro Hashiguchi; Keiko Higashi; Itsuro Higuchi; Hiroshi Takashima
Inclusion body myositis coexisting with hypertrophic cardiomyopathy: an autopsy study.
Itsuro Higuchi
[Collagen VI-related muscle disorders].

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2012: Chihiro Yonee; Sarah P Young; Itsuro Higuchi; Yoshihiro Maegaki; Shinsuke Maruyama; Eiji Nanba; Aya Narita; Kousaku Ohno; Mitsuo Toyoshima; Yoshifumi Kawano
Quantitative computed tomography for enzyme replacement therapy in Pompe disease.
Brain & development 2012;34(10):834-9.
2012: Yukie Inamori; Teruhiko Inoue; Yoshio Mitsuyama; Ryuichi Okubo; Yusuke Sakiyama; Tadafumi Shiraishi; Kimiyoshi Arimura; Akihiro Hashiguchi; Keiko Higashi; Itsuro Higuchi; Hiroshi Takashima
Inclusion body myositis coexisting with hypertrophic cardiomyopathy: an autopsy study.
Neuromuscular disorders : NMD 2012;22(8):747-54.
2011: Itsuro Higuchi
[Collagen VI-related muscle disorders].
Brain and nerve = Shinkei kenkyū no shinpo 2011;63(11):1169-78.
2011: Yuji Okamoto; Yusuke Sakiyama; Kimiyoshi Arimura; Itsuro Higuchi; Masanori Nakagawa; Shoko Tokunaga; Osamu Watanabe; Hiroshi Takashima
A new mitochondria-related disease showing myopathy with episodic hyper-creatine kinase-emia.
Annals of neurology 2011;70(3):486-92.
2011: Yusuke Sakiyama; Yuji Okamoto; Itsuro Higuchi; Yukie Inamori; Yoko Sangatsuda; Kumiko Michizono; Osamu Watanabe; Hideyuki Hatakeyama; Yu-ichi Goto; Kimiyoshi Arimura; Hiroshi Takashima
A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy.
Acta neuropathologica 2011;121(6):775-83.
2011: Maiko Kato; Masayuki Nakamura; Mio Ichiba; Akiyuki Tomiyasu; Hirochika Shimo; Itsuro Higuchi; Shu-ichi Ueno; Akira Sano
Mitochondrial DNA deletion mutations in patients with neuropsychiatric symptoms.
Neuroscience research 2011;69(4):331-6.
2008: Eiji Matsuura; Fujio Umehara; Hirohisa Nose; Itsuro Higuchi; E Matsuoka; Koutarou Izumi; Ryuji Kubota; Mineki Saito; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan.
Journal of neuropathology and experimental neurology 2008;67(1):41-9.
2007: Kimiyoshi Arimura; Yumiko Arimura; Arlene R Ng; Shun-Ichi Sakoda; Itsuro Higuchi
Muscle membrane excitability after exercise in thyrotoxic periodic paralysis and thyrotoxicosis without periodic paralysis.
Muscle & nerve 2007;36(6):784-8.
2007: Hirotou Moriyama; Masahito Ichiki; Takumi Arime; Akihiro Hashiguchi; Naoaki Kanda; Kenichi Ikeda; Hiroshi Takashima; Itsuro Higuchi; Mitsuhiro Osame; Kimiyoshi Arimura
[Mitochondrial encephalomyopathy with elderly onset of psychiatric disorder].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2007;96(11):2536-8.
2007: Itsuro Higuchi; Akihiro Hashiguchi; Eiji Matsuura; Keiko Higashi; Tadafumi Shiraishi; Noriko Hirata; Kimiyoshi Arimura; Mitsuhiro Osame
Different pattern of HSP47 expression in skeletal muscle of patients with neuromuscular diseases.
Neuromuscular disorders : NMD 2007;17(3):221-6.
2006: Fujio Umehara; Hideki Ookatsu; Daisuke Hayashi; Akifumi Uchida; Yukari Douchi; Hisashi Kawabata; Rina Goto; Akihiro Hashiguchi; Eiji Matsuura; Ryuichi Okubo; Itsuro Higuchi; Kimiyoshi Arimura; Yukifumi Nawa; Mitsuhiro Osame
MRI studies of spinal visceral larva migrans syndrome.
Journal of the neurological sciences 2006;249(1):7-12.
2006: Yuji Okamoto; Hiroshi Takashima; Itsuro Higuchi; Wataru Matsuyama; Masahito Suehara; Yasushi Nishihira; Akihiro Hashiguchi; Ryuki Hirano; Arlene R Ng; Masanori Nakagawa; Shuji Izumo; Mitsuhiro Osame; Kimiyoshi Arimura
Molecular mechanism of rigid spine with muscular dystrophy type 1 caused by novel mutations of selenoprotein N gene.
Neurogenetics 2006;7(3):175-83.
2006: Yoshiharu Takata; Tadafumi Shiraishi; Eiji Matsuura; Takayo Arisato; Ryuichi Okubo; Itsuro Higuchi; Fujio Umehara; Mitsuhiro Osame; Kimiyoshi Arimura; Kazuhide Hashiguchi
[n-Hexane polyneuropathy presenting with CIDP-like features].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2006;95(5):933-5.
2006: Arlene R Ng; Kimiyoshi Arimura; K Akataki; K Mita; Itsuro Higuchi; Mitsuhiro Osame
Mechanomyographic determination of post-activation potentiation in myopathies.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2006;117(1):232-9.
2006: Keiko Higashi; Itsuro Higuchi; Takahito Niiyama; Yuichi Uchida; Tadafumi Shiraishi; Akihiro Hashiguchi; Akiko Saito; Takashi Horikiri; Masahito Suehara; Kimiyoshi Arimura; Mitsuhiro Osame
Abnormal expression of proteoglycans in Ullrich's disease with collagen VI deficiency.
Muscle & nerve 2006;33(1):120-6.
2005: Konosuke Yamasaki; Shuitsu Harada; Itsuro Higuchi; Mitsuhiro Osame; Gakuji Ito
Fatigue and damage to the masseter muscle by prolonged low-frequency stimulation in the rat.
Archives of oral biology 2005;50(12):1005-13.
2005: Itsuro Higuchi
[Collagenopathy (Ullrich congenital muscular dystrophy, Bethlem myopathy)].
Rinshō shinkeigaku = Clinical neurology 2005;45(11):935-7.
2005: Yuko Kijima; Heiji Yoshinaka; Itsuro Higuchi; Tetsuhiro Owaki; Takashi Aikou
A case of amyotrophic lateral sclerosis and breast cancer.
Breast cancer (Tokyo, Japan) 2005;12(1):57-9.
2004: Yasuyuki Nobuhara; K Nakahara; Itsuro Higuchi; T Yoshida; S Fushiki; Mitsuhiro Osame; Kimiyoshi Arimura; Masanori Nakagawa
Juvenile form of Alexander disease with GFAP mutation and mitochondrial abnormality.
Neurology 2004;63(7):1302-4.
2003: Takahito Niiyama; Itsuro Higuchi; Teruto Hashiguchi; Masahito Suehara; Yuichi Uchida; Takashi Horikiri; Tadafumi Shiraishi; Akiko Saitou; Jing Hu; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Capillary changes in skeletal muscle of patients with Ullrich's disease with collagen VI deficiency.
Acta neuropathologica 2003;106(2):137-42.
2003: Itsuro Higuchi; Takashi Horikiri; Takahito Niiyama; Masahito Suehara; Tadafumi Shiraishi; Jing Hu; Yuichi Uchida; Akiko Saito; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Pathological characteristics of skeletal muscle in Ullrich's disease with collagen VI deficiency.
Neuromuscular disorders : NMD 2003;13(4):310-6.
2002: Takahito Niiyama; Itsuro Higuchi; Yuichi Uchida; Takashi Horikiri; Kimiyoshi Arimura; Mitsuhiro Osame
Skeletal muscle abnormalities in two patients with dystonia.
Acta neuropathologica 2002;104(6):670-3.
2002: Akiko Saito; Itsuro Higuchi; Masanori Nakagawa; Mineki Saito; Keiko Hirata; Masahito Suehara; Yoshihiro Yoshida; Toshiaki Takahashi; Masashi Aoki; Mitsuhiro Osame
Miyoshi myopathy patients with novel 5' splicing donor site mutations showed different dysferlin immunostaining at the sarcolemma.
Acta neuropathologica 2002;104(6):615-20.
2002: Jing Hu; Itsuro Higuchi; Tadafumi Shiraishi; Masahito Suehara; Takahito Niiyama; Takashi Horikiri; Yuichi Uchida; Akiko Saito; Mitsuhiro Osame
Fibronectin receptor reduction in skin and fibroblasts of patients with Ullrich's disease.
Muscle & nerve 2002;26(5):696-701.
2002: Mineki Saito; Itsuro Higuchi; Akiko Saito; Shuji Izumo; Koichiro Usuku; Charles R M Bangham; Mitsuhiro Osame
Molecular analysis of T cell clonotypes in muscle-infiltrating lymphocytes from patients with human T lymphotropic virus type 1 polymyositis.
The Journal of infectious diseases 2002;186(9):1231-41.
2002: Saeid Morovvati; Masanori Nakagawa; Y Sato; K Hamada; Itsuro Higuchi; Mitsuhiro Osame
Phenotypes and mitochondrial DNA substitutions in families with A3243G mutation.
Acta neurologica Scandinavica 2002;106(2):104-8.
2002: Misako Haraguchi; Hiroaki Tsujimoto; Masakazu Fukushima; Itsuro Higuchi; Hideto Kuribayashi; Hideo Utsumi; Atsuo Nakayama; Yoshio Hashizume; Junko Hirato; Hiroki Yoshida; Hiromitsu Hara; Shinjiro Hamano; Hiroaki Kawaguchi; Tatsuhiko Furukawa; Kohei Miyazono; Fuyuki Ishikawa; Hideo Toyoshima; Tadashi Kaname; Masaharu Komatsu; Zhe-Sheng Chen; Takenari Gotanda; Tokushi Tachiwada; Tomoyuki Sumizawa; Kazutaka Miyadera; Mitsuhiro Osame; Hiroki Yoshida; Tetsuo Noda; Yuji Yamada; Shin-ichi Akiyama
Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice.
Molecular and cellular biology 2002;22(14):5212-21.
2002: Takahito Niiyama; Itsuro Higuchi; Masahito Suehara; Teruto Hashiguchi; Tadafumi Shiraishi; Masanori Nakagawa; Kimiyoshi Arimura; Ikuro Maruyama; Mitsuhiro Osame
Electron microscopic abnormalities of skeletal muscle in patients with collagen VI deficiency in Ullrich's disease.
Acta neuropathologica 2002;104(1):67-71.
2002: Takayo Arisato; Itsuro Higuchi; Masanori Nakagawa
[Single deletion of mitochondrial DNA: CPEO, Kearns-Sayre syndrome].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():458-61.
2002: Masaru Inose; Itsuro Higuchi
[Autosomal recessive chronic progressive external ophthalmoplegia].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():455-7.
2002: Itsuro Higuchi; Masanori Nakagawa
[Autosomal dominant chronic progressive external ophthalmoplegia].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 4():450-4.
2002: Takahito Niiyama; Itsuro Higuchi; Shunichi Sakoda; Tsuyoshi Matsumura; Hidetoshi Fukunaga; Mitsuhiro Osame
Diagnosis of dystrophinopathy by skin biopsy.
Muscle & nerve 2002;25(3):398-401.
2002: Itsuro Higuchi; Kimiyoshi Arimura
[Polymyositis, dermatomyositis].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 1():364-70.
2002: Jing Hu; Itsuro Higuchi; Yoshihiro Yoshida; Tadafumi Shiraishi; Mitsuhiro Osame
Expression of midkine in regenerating skeletal muscle fibers and cultured myoblasts of human skeletal muscle.
European neurology 2002;47(1):20-5.
2002: Yoshihiro Sato; Masaru Inose; Itsuro Higuchi; Fujio Higuchi; Izumi Kondo
Changes in the supporting muscles of the fractured hip in elderly women.
Bone 2002;30(1):325-30.
2001: Itsuro Higuchi; Tadafumi Shiraishi; Teruto Hashiguchi; Masahito Suehara; Takahito Niiyama; Masanori Nakagawa; Kimiyoshi Arimura; Ikuro Maruyama; Mitsuhiro Osame
Frameshift mutation in the collagen VI gene causes Ullrich's disease.
Annals of neurology 2001;50(2):261-5.
2001: Toshio Matsuzaki; Masanori Nakagawa; Masahiro Nagai; Koichiro Usuku; Itsuro Higuchi; Kimiyoshi Arimura; H Kubota; Shuji Izumo; suminori akiba; Mitsuhiro Osame
HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years.
Journal of neurovirology 2001;7(3):228-34.
2001: Masanori Nakagawa; Toshio Matsuzaki; Masahito Suehara; N Kanzato; Hiroshi Takashima; Itsuro Higuchi; T Matsumura; K Goto; K Arahata; Mitsuhiro Osame
Phenotypic variation in a large Japanese family with Miyoshi myopathy with nonsense mutation in exon 19 of dysferlin gene.
Journal of the neurological sciences 2001;184(1):15-9.
2001: Itsuro Higuchi
[Myoadenylate deaminase deficiency].
Ryōikibetsu shōkōgun shirīzu 2001;(36):122-5.
2001: Masanori Nakagawa; Itsuro Higuchi
[Facioscapulohumeral muscular dystrophy].
Ryōikibetsu shōkōgun shirīzu 2001;(35):39-45.
2001: Takahito Niiyama; Itsuro Higuchi
[Eosinophilia myalgia syndrome, toxic oil syndrome].
Ryōikibetsu shōkōgun shirīzu 2001;(35):358-60.
2001: Akiko Saito; Itsuro Higuchi
[Eosinophilic polymyositis].
Ryōikibetsu shōkōgun shirīzu 2001;(35):350-3.
2001: Masaru Inose; Itsuro Higuchi
[Other viral myositis].
Ryōikibetsu shōkōgun shirīzu 2001;(35):174-7.
2000: Toshio Matsuzaki; Masanori Nakagawa; Masahiro Nagai; Yasuyuki Nobuhara; Koichiro Usuku; Itsuro Higuchi; K Takahashi; Takashi Moritoyo; Kimiyoshi Arimura; Shuji Izumo; suminori akiba; Mitsuhiro Osame
HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) with amyotrophic lateral sclerosis-like manifestations.
Journal of neurovirology 2000;6(6):544-8.
2000: Itsuro Higuchi; Takahito Niiyama; Yuichi Uchida; Masaru Inose; Jing Hu; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Microvascular endothelial abnormality in skeletal muscle from a patient with gastric cancer without dermatomyositis.
Acta neuropathologica 2000;100(6):718-22.
2000: M Abe; Itsuro Higuchi; H Morisaki; T Morisaki; Mitsuhiro Osame
Myoadenylate deaminase deficiency with progressive muscle weakness and atrophy caused by new missense mutations in AMPD1 gene: case report in a Japanese patient.
Neuromuscular disorders : NMD 2000;10(7):472-7.
2000: Munekazu Yamakuchi; Itsuro Higuchi; S Masuda; Y Ohira; T Kubo; Y Kato; Ikuro Maruyama; Isao Kitajima
Type I muscle atrophy caused by microgravity-induced decrease of myocyte enhancer factor 2C (MEF2C) protein expression.
FEBS letters 2000;477(1-2):135-40.
2000: Y Sato; M Nakagawa; Itsuro Higuchi; Mitsuhiro Osame; E Naito; K Oizumi
Mitochondrial myopathy and familial thiamine deficiency.
Muscle & nerve 2000;23(7):1069-75.
2000: Akiko Saito; Itsuro Higuchi; Masanori Nakagawa; M Saito; Yuichi Uchida; Masaru Inose; Takefumi Kasai; Takahito Niiyama; Hidetoshi Fukunaga; Kimiyoshi Arimura; Mitsuhiro Osame
An overexpression of fibroblast growth factor (FGF) and FGF receptor 4 in a severe clinical phenotype of facioscapulohumeral muscular dystrophy.
Muscle & nerve 2000;23(4):490-7.
2000: H Yamada; Masanori Nakagawa; Itsuro Higuchi; Takashi Horikiri; Mitsuhiro Osame
Detection of DNA fragmentation of myonuclei in myotonic dystrophy by double staining with anti-emerin antibody and by nick end-labeling.
Journal of the neurological sciences 2000;173(2):97-102.
2000: Jing Hu; Itsuro Higuchi; Masaru Inose; Takahito Niiyama; Yuichi Uchida; Mitsuhiro Osame
Characteristic expression of thrombomodulin in the muscle sarcoplasm in patients with the acute phase of rhabdomyolysis.
European neurology 2000;43(3):174-80.
1999: Takahito Niiyama; Itsuro Higuchi; Ikuro Maruyama; Mitsuhiro Osame
Expression of thrombomodulin, caveolin-3, and desmin on muscle fibers in neuromuscular diseases.
Muscle & nerve 1999;22(12):1713-6.
1999: Ryuichi Ohkubo; Masanori Nakagawa; Itsuro Higuchi; Y Utatsu; H Miyazato; Yoshihiko Atsuchi; Mitsuhiro Osame
Familial skeletal myopathy with atrioventricular block.
Internal medicine (Tokyo, Japan) 1999;38(11):856-60.
1999: Itsuro Higuchi; Takahito Niiyama; Yuichi Uchida; Masaru Inose; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Multiple episodes of thrombosis in a patient with Becker muscular dystrophy with marked expression of utrophin on the muscle cell membrane.
Acta neuropathologica 1999;98(3):313-6.
1999: Masaru Inose; Itsuro Higuchi; Kowa Yoshimine; Kimiyoshi Arimura; Mitsuhiro Osame; Shuji Izumo; Y Hokezu
[A study of clinical symptoms, muscle pathology, therapeutic response, and prognosis of myositis in patients with HTLV-1 associated myelopathy (HAM)].
Rinshō shinkeigaku = Clinical neurology 1999;39(8):807-11.
1999: Masaru Inose; Itsuro Higuchi; Masanori Nakagawa; N Kashio; Mitsuhiro Osame
Caveolin-3 and sarcoglycans in the vacuolar myopathies and centronuclear myopathy.
Muscle & nerve 1999;22(8):1080-6.
1999: Itsuro Higuchi; H Kawai; M Kawajiri; Hidetoshi Fukunaga; Takashi Horikiri; Takahito Niiyama; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Statistically significant differences in the number of CD24 positive muscle fibers and satellite cells between sarcoglycanopathy and age-matched Becker muscular dystrophy patients.
Internal medicine (Tokyo, Japan) 1999;38(5):412-5.
1999: T Kasai; Hitoshi Ikeda; Utano Tomaru; I Yamashita; Osamu Ohya; K Morita; A Wakisaka; E Matsuoka; Takashi Moritoyo; K Hashimoto; Itsuro Higuchi; Shuji Izumo; Mitsuhiro Osame; Takashi Yoshiki
A rat model of human T lymphocyte virus type I (HTLV-I) infection: in situ detection of HTLV-I provirus DNA in microglia/macrophages in affected spinal cords of rats with HTLV-I-induced chronic progressive myeloneuropathy.
Acta neuropathologica 1999;97(2):107-12.
1999: Keiko Hirata; Masanori Nakagawa; Itsuro Higuchi; K Hashimoto; K Hanada; K Takahashi; Takahito Niiyama; K Izumi; S Sakoda; H Yamada; Mitsuhiro Osame
Adult onset limb-girdle type mitochondrial myopathy with a mitochondrial DNA np8291 A-to-G substitution.
Journal of human genetics 1999;44(3):210-4.
1998: E Matsuoka; Norihiro Takenouchi; K Hashimoto; N Kashio; Takashi Moritoyo; Itsuro Higuchi; Yasushi Isashiki; Eiichi Sato; Mitsuhiro Osame; Shuji Izumo
Perivascular T cells are infected with HTLV-I in the spinal cord lesions with HTLV-I-associated myelopathy/tropical spastic paraparesis: double staining of immunohistochemistry and polymerase chain reaction in situ hybridization.
Acta neuropathologica 1998;96(4):340-6.
1998: K Nakahara; M Kuriyama; Yoshito Sonoda; H Yoshidome; H Nakagawa; J Fujiyama; Itsuro Higuchi; Mitsuhiro Osame
Myopathy induced by HMG-CoA reductase inhibitors in rabbits: a pathological, electrophysiological, and biochemical study.
Toxicology and applied pharmacology 1998;152(1):99-106.
1998: Itsuro Higuchi; H Kawai; Y Umaki; M Kawajiri; K Adachi; Hidetoshi Fukunaga; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Different manners of sarcoglycan expression in genetically proven alpha-sarcoglycan deficiency and gamma-sarcoglycan deficiency.
Acta neuropathologica 1998;96(2):202-6.
1998: K Hashimoto; Itsuro Higuchi; Mitsuhiro Osame; Shuji Izumo
Quantitative in situ PCR assay of HTLV-1 infected cells in peripheral blood lymphocytes of patients with ATL, HAM/TSP and asymptomatic carriers.
Journal of the neurological sciences 1998;159(1):67-72.
1998: Yasushi Isashiki; Masanori Nakagawa; Norio Ohba; K Kamimura; Y Sakoda; Itsuro Higuchi; S Izumo; Mitsuhiro Osame
Retinal manifestations in mitochondrial diseases associated with mitochondrial DNA mutation.
Acta ophthalmologica Scandinavica 1998;76(1):6-13.
1997: Itsuro Higuchi; H Iwaki; H Kawai; T Endo; M Kunishige; Hidetoshi Fukunaga; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
New missense mutation in the alpha-sarcoglycan gene in a Japanese patient with severe childhood autosomal recessive muscular dystrophy with incomplete alpha-sarcoglycan deficiency.
Journal of the neurological sciences 1997;153(1):100-5.
1997: Itsuro Higuchi; Mitsuhiro Osame
[Recent progress of molecular immunology on inflammatory myopathy].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(12):3331-5.
1997: Anat Achiron; Itsuro Higuchi; Norihiro Takenouchi; E Matsuoka; K Hashimoto; Shuji Izumo; Batya Shohat; Mitsuhiro Osame
Detection of HTLV type I provirus by in situ polymerase chain reaction in mouthwash mononuclear cells of HAM/TSP patients and HTLV type I carriers.
AIDS research and human retroviruses 1997;13(12):1067-70.
1997: Fujio Umehara; Itsuro Higuchi; K Tanaka; Takahito Niiyama; J Ezaki; E Kominami; Mitsuhiro Osame
Accumulation of mitochondrial ATP synthase subunit c in muscle in a patient with neuronal ceroid lipofuscinosis (late infantile form).
Acta neuropathologica 1997;93(6):628-32.
1997: Hiroshi Takashima; Masanori Nakagawa; K Nakahara; Masahito Suehara; Toshio Matsuzaki; Itsuro Higuchi; H Higa; Kimiyoshi Arimura; T Iwamasa; Shuji Izumo; Mitsuhiro Osame
A new type of hereditary motor and sensory neuropathy linked to chromosome 3.
Annals of neurology 1997;41(6):771-80.
1997: Masanori Nakagawa; Toshio Matsuzaki; Itsuro Higuchi; Hidetoshi Fukunaga; T Inui; S Nagamitsu; H Yamada; Kimiyoshi Arimura; Mitsuhiro Osame
Facioscapulohumeral muscular dystrophy: clinical diversity and genetic abnormalities in Japanese patients.
Internal medicine (Tokyo, Japan) 1997;36(5):333-9.
1997: Mitsuhiro Osame; Masanori Nakagawa; Fujio Umehara; Shinji Ijichi; Takashi Moritoyo; Itsuro Higuchi; Koichiro Usuku; Kimiyoshi Arimura; Shuji Izumo
Recent studies on the epidemiology, clinical features and pathogenic mechanisms of HTLV-I associated myelopathy (HAM/TSP) and other diseases associated to HTLV.
Journal of neurovirology 1997;3 Suppl 1():S50-1.
1997: Y Utatsu; Hiroshi Takashima; Kumiko Michizono; N Kanda; K Endou; Y Mitsuyama; T Fujimoto; Masahiro Nagai; Fujio Umehara; Itsuro Higuchi; Kimiyoshi Arimura; Masanori Nakagawa; Mitsuhiro Osame
Autosomal dominant early onset dementia and leukoencephalopathy in a Japanese family: clinical, neuroimaging and genetic studies.
Journal of the neurological sciences 1997;147(1):55-62.
1997: Kimiyoshi Arimura; Osamu Watanabe; Isao Kitajima; Masahito Suehara; S Minato; Yoshito Sonoda; Itsuro Higuchi; S Takenaga; Ikuro Maruyama; Mitsuhiro Osame
Antibodies to potassium channels of PC12 in serum of Isaacs' syndrome: Western blot and immunohistochemical studies.
Muscle & nerve 1997;20(3):299-305.
1996: Itsuro Higuchi; H Fukunaga; F Motokura; T Goto; N Niiyama; Masaru Inose; K Izumi; R Ohkubo; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Characteristic expression of cell adhesion molecules in adhalin deficiency.
Journal of the neurological sciences 1996;143(1-2):79-83.
1996: Masanori Nakagawa; K Nakahara; Y Maruyama; Masaharu Kawabata; Itsuro Higuchi; H Kubota; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.
Journal of neurovirology 1996;2(5):345-55.
1996: Itsuro Higuchi; K Hashimoto; E Matsuoka; R Rosales; Masanori Nakagawa; Kimiyoshi Arimura; Shuji Izumo; Mitsuhiro Osame
The main HTLV-I-harboring cells in the muscles of viral carriers with polymyositis are not macrophages but CD4+ lymphocytes.
Acta neuropathologica 1996;92(4):358-61.
1996: Masanori Nakagawa; Itsuro Higuchi; H Yoshidome; Yasushi Isashiki; R Ohkubo; S Kaseda; H Iwaki; H Fukunaga; Mitsuhiro Osame
Familial facioscapulohumeral muscular dystrophy: phenotypic diversity and genetic abnormality.
Acta neurologica Scandinavica 1996;93(2-3):189-92.
1996: Shinji Ijichi; Masanori Nakagawa; Fujio Umehara; Itsuro Higuchi; Kimiyoshi Arimura; Shuji Izumo; Mitsuhiro Osame
HAM/TSP: recent perspectives in Japan.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;13 Suppl 1():S26-32.
1995: H Yamada; Masanori Nakagawa; Itsuro Higuchi; R Ohkubo; Mitsuhiro Osame
Type II muscle fibers are stained by anti-Fas antibody.
Journal of the neurological sciences 1995;134(1-2):115-8.
1995: Itsuro Higuchi; H Fukunaga; K Matsumura; Masaru Inose; K Izumi; R Okubo; Masanori Nakagawa; T Shimizu; Mitsuhiro Osame
Abnormal expression of heparin sulfate proteoglycan on basal lamina of muscle fibers in two Japanese patients with adhalin deficiency.
Neuromuscular disorders : NMD 1995;5(6):467-74.
1995: Itsuro Higuchi; K Hashimoto; N Kashio; Shuji Izumo; Masaru Inose; K Izumi; R Ohkubo; Masanori Nakagawa; Kimiyoshi Arimura; Mitsuhiro Osame
Detection of HTLV-I provirus by in situ polymerase chain reaction in mononuclear inflammatory cells in skeletal muscle of viral carriers with polymyositis.
Muscle & nerve 1995;18(8):854-8.
1995: Masanori Nakagawa; Y Kaminishi; Yasushi Isashiki; H Yamada; Itsuro Higuchi; Y Uchida; Mitsuhiro Osame
Familial mitochondrial encephalomyopathy with deaf-mutism, ophthalmoplegia and leukodystrophy.
Acta neurologica Scandinavica 1995;92(1):102-8.
1995: M Maeda; Shoichiro Nakao; H Miyazato; M Setoguchi; S Arima; Itsuro Higuchi; Mitsuhiro Osame; A Taira; K Nomoto; Hitoshi Toda
Cardiac dystrophin abnormalities in Becker muscular dystrophy assessed by endomyocardial biopsy.
American heart journal 1995;129(4):702-7.
1995: R Anan; Masanori Nakagawa; M Miyata; Itsuro Higuchi; Shoichiro Nakao; Masahito Suehara; Mitsuhiro Osame; H Tanaka
Cardiac involvement in mitochondrial diseases. A study on 17 patients with documented mitochondrial DNA defects.
Circulation 1995;91(4):955-61.
1995: Itsuro Higuchi; K Hashimoto; N Kashio; Shuji Izumo; H Matsuoka; Masanori Nakagawa; Mitsuhiro Osame
In situ polymerase chain reaction detection of HTLV-I provirus and expression of the p53 tumor suppressor gene in infiltrating cells in skeletal muscle from a patient with adult T cell leukemia.
Acta neuropathologica 1995;90(3):323-7.
1995: H Arimura; M Kuriyama; Itsuro Higuchi; M Tokimura; Mitsuhiro Osame
[Paroxysmal dystonic choreoathetosis with chronic hemolytic anemia and morphologically abnormal erythrocytes].
Rinshō shinkeigaku = Clinical neurology 1995;35(1):29-33.
1994: F Usuki; S Takenaga; Itsuro Higuchi; N Kashio; Masanori Nakagawa; Mitsuhiro Osame
Morphologic findings in biopsied skeletal muscle and cultured fibroblasts from a female patient with Danon's disease (lysosomal glycogen storage disease without acid maltase deficiency).
Journal of the neurological sciences 1994;127(1):54-60.
1994: Itsuro Higuchi; H Yamada; H Fukunaga; H Iwaki; R Okubo; Masanori Nakagawa; Mitsuhiro Osame; S L Roberds; T Shimizu; K P Campbell
Abnormal expression of laminin suggests disturbance of sarcolemma-extracellular matrix interaction in Japanese patients with autosomal recessive muscular dystrophy deficient in adhalin.
The Journal of clinical investigation 1994;94(2):601-6.
1994: Youichi Hokezu; Itsuro Higuchi; S Yanai; M Nagai; Keiji Nagamatsu
[A family case of HAM and HTLV-I carrier including two sisters presenting with myositis].
Rinshō shinkeigaku = Clinical neurology 1994;34(6):563-8.
1994: Itsuro Higuchi; Takahito Niiyama; H Fukunaga; K Nakamura; Masanori Nakagawa; Mitsuhiro Osame
Dystrophin-related protein in Becker muscular dystrophy.
Internal medicine (Tokyo, Japan) 1994;33(6):334-6.
1993: Itsuro Higuchi; E S Montemayor; Shuji Izumo; Masaru Inose; Mitsuhiro Osame
Immunohistochemical characteristics of polymyositis in patients with HTLV-I-associated myelopathy and HTLV-I carriers.
Muscle & nerve 1993;16(5):472-6.
1993: Itsuro Higuchi; K Nakamura; Masanori Nakagawa; N Nakamura; F Usuki; Masaru Inose; Mitsuhiro Osame
Steroid-responsive myalgia in a patient with Becker muscular dystrophy.
Journal of the neurological sciences 1993;115(2):219-22.
1993: K Matsumuro; Shuji Izumo; Y Minauchi; Masaru Inose; Itsuro Higuchi; Mitsuhiro Osame
Chronic demyelinating neuropathy and intra-axonal polyglucosan bodies.
Acta neuropathologica 1993;86(1):95-9.
1993: K Matsumuro; Shuji Izumo; Itsuro Higuchi; A T Ronquillo; K Takahashi; Mitsuhiro Osame
Experimental germanium dioxide-induced neuropathy in rats.
Acta neuropathologica 1993;86(6):547-53.
1993: Itsuro Higuchi; T Yamano; M Kuriyama; Kiyoshige Niina; M Nakase; M Umemoto; H Take; Mitsuhiro Osame
Histochemical and ultrastructural pathology of skeletal muscle in a patient with abetalipoproteinemia.
Acta neuropathologica 1993;86(5):529-31.
1992: R Anan; Masanori Nakagawa; Itsuro Higuchi; Shoichiro Nakao; K Nomoto; H Tanaka
Deletion of mitochondrial DNA in the endomyocardial biopsy sample from a patient with Kearns-Sayre syndrome.
European heart journal 1992;13(12):1718-9.
1992: K Nakahara; M Kuriyama; H Yoshidome; K Nagata; T Nagado; Masanori Nakagawa; Kimiyoshi Arimura; Itsuro Higuchi; Mitsuhiro Osame
Experimental simvastatin-induced myopathy in rabbits.
Journal of the neurological sciences 1992;113(1):114-7.
1992: T Ijichi; Itsuro Higuchi; H Fukunaga; Shuji Izumo; Mitsuhiro Osame
Lymphocyte subsets in muscle biopsies of human T-lymphotropic virus type I carriers with polymyositis.
Internal medicine (Tokyo, Japan) 1992;31(8):973-7.
1992: Masaru Inose; Itsuro Higuchi; Kowa Yoshimine; Masahito Suehara; Shuji Izumo; Kimiyoshi Arimura; Mitsuhiro Osame
Pathological changes in skeletal muscle in HTLV-I-associated myelopathy.
Journal of the neurological sciences 1992;110(1-2):73-8.
1992: Itsuro Higuchi; H Fukunaga; F Usuki; Takashi Moritoyo; Mitsuhiro Osame
Phenotypic Duchenne muscular dystrophy with C-terminal domain.
Pediatric neurology 1992;8(4):310-2.
1992: Shuji Izumo; T Ijichi; Itsuro Higuchi; A Tashiro; K Takahashi; Mitsuhiro Osame
Neuropathology of HTLV-I-associated myelopathy--a report of two autopsy cases.
Acta paediatrica Japonica; Overseas edition 1992;34(3):358-64.
1992: H Fukunaga; Takashi Moritoyo; R Okubo; Itsuro Higuchi; Mitsuhiro Osame
[Clinical and histochemical findings in spinal muscular atrophy].
Nō to shinkei = Brain and nerve 1992;44(6):547-52.
1992: R Anan; Itsuro Higuchi; K Ichinari; K Kubota; Akira Kisanuki; S Arima; Shoichiro Nakao; Mitsuhiro Osame; H Tanaka
Myocardial patchy staining of dystrophin in Becker's muscular dystrophy associated with cardiomyopathy.
American heart journal 1992;123(4 Pt 1):1088-9.
1992: Y Honda; M Kuriyama; Itsuro Higuchi; J Fujiyama; H Yoshida; Mitsuhiro Osame
Muscular involvement in lysosomal acid lipase deficiency in rats.
Journal of the neurological sciences 1992;108(2):189-95.
1992: H Fukunaga; Itsuro Higuchi; F Usuki; Takashi Moritoyo; R Okubo
[Clinical significance of serum cardiac myosin light chain I in patients with Duchenne muscular dystrophy].
Nō to shinkei = Brain and nerve 1992;44(2):131-5.
1992: Itsuro Higuchi; M Nerenberg; Kowa Yoshimine; M Yoshida; H Fukunaga; K Tajima; Mitsuhiro Osame
Failure to detect HTLV-I by in situ hybridization in the biopsied muscles of viral carriers with polymyositis.
Muscle & nerve 1992;15(1):43-7.
1991: Itsuro Higuchi; M Nerenberg; T Ijichi; H Fukunaga; Kimiyoshi Arimura; F Usuki; M Kuriyama; Mitsuhiro Osame
Vacuolar myositis with expression of both MHC class I and class II antigens on skeletal muscle fibers.
Journal of the neurological sciences 1991;106(1):60-6.
1991: N Kashio; F Usuki; T Akamine; S Nakagawa; Itsuro Higuchi; K Nakahara; A Okada; Mitsuhiro Osame; Fusayoshi Murata
Cardiomyopathy, mental retardation, and autophagic vacuolar myopathy. Abnormal MRI findings in the head.
Journal of the neurological sciences 1991;105(1):1-5.
1991: Masanori Nakagawa; M Tokimura; M Kuriyama; Itsuro Higuchi; Mitsuhiro Osame
[Chronic progressive external ophthalmoplegia (CPEO); mitochondrial DNA deletion, brain MRI and electrophysiological studies].
Rinshō shinkeigaku = Clinical neurology 1991;31(9):981-6.
1991: T Ijichi; Shuji Izumo; K Takahashi; A Tashiro; Itsuro Higuchi; Mitsuhiro Osame
Lymphocyte subsets in sural nerves from patients with vasculitic neuropathy.
Muscle & nerve 1991;14(6):574-5.
1991: F Usuki; Itsuro Higuchi; Y Soejima; M Hattori; Ikuro Maruyama; Mitsuhiro Osame
Human acid maltase-deficient myogenic cell transformation with origin-defective SV40: characterization of a cloned line.
Muscle & nerve 1991;14(3):245-52.
1991: Itsuro Higuchi; K Takahashi; K Nakahara; Shuji Izumo; Masanori Nakagawa; Mitsuhiro Osame
Experimental germanium myopathy.
Acta neuropathologica 1991;82(1):55-9.
1991: Masanori Nakagawa; K Nakahara; H Yoshidome; Masahito Suehara; Itsuro Higuchi; J Fujiyama; A Nakamura; Ryuji Kubota; S Takenaga; K Arahata
Epidemiology of progressive muscular dystrophy in Okinawa, Japan. Classification with molecular biological techniques.
Neuroepidemiology 1991;10(4):185-91.
1989: Y Yoshida; R Hamada; H Kamitsuchibashi; K Yamamoto; Masanori Nakagawa; Shuji Izumo; Itsuro Higuchi; Y Soejima; Mitsuhiro Osame; A Igata
Determination of urine thiocyanate in patients with amyotrophic lateral sclerosis.
Acta neurologica Scandinavica 1989;80(5):444-50.
1989: Itsuro Higuchi; Shuji Izumo; M Kuriyama; Masahito Suehara; Masanori Nakagawa; H Fukunaga; Mitsuhiro Osame; S Ohtsubo; K Miyata
Germanium myopathy: clinical and experimental pathological studies.
Acta neuropathologica 1989;79(3):300-4.
1984: Y Yoshida; R Hamada; H Kamitsuchibashi; K Yamamoto; Shuji Izumo; Itsuro Higuchi; A Igata; S Kaneko; Y Sato
[Determination of urine thiocyanate in patients with amyotrophic lateral sclerosis].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1984;73(3):316-22.