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Makoto Higuchi

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Ryuichi Harada; Makoto Higuchi; Ren Iwata; Yukitsuka Kudo; Masahiro Maruyama; Nobuyuki Okamura; Tetsuro Tago; Hiroyuki Arai; Shozo Furumoto; Takeo Yoshikawa; Kazuhiko Yanai
Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology.
Hironori Fujiwara; Masahiro Tabuchi; Takuji Yamaguchi; Koh Iwasaki; Katsutoshi Furukawa; Kyoji Sekiguchi; Yasushi Ikarashi; Yukitsuka Kudo; Makoto Higuchi; Takaomi C Saido; Sumihiro Maeda; Akihiko Takashima; Masahiko Hara; Nobuo Yaegashi; Yoshio Kase; Hiroyuki Arai
A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo.
M He; T Ohrui; M Maruyama; N Tomita; K Nakayama; Makoto Higuchi; K Furukawa; Hiroyuki Arai
ACE activity in CSF of patients with mild cognitive impairment and Alzheimer disease.

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All Publications

2013: Ryuichi Harada; Makoto Higuchi; Ren Iwata; Yukitsuka Kudo; Masahiro Maruyama; Nobuyuki Okamura; Tetsuro Tago; Hiroyuki Arai; Shozo Furumoto; Takeo Yoshikawa; Kazuhiko Yanai
Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology.
European journal of nuclear medicine and molecular imaging 2013;40(1):125-32.
2009: Hironori Fujiwara; Masahiro Tabuchi; Takuji Yamaguchi; Koh Iwasaki; Katsutoshi Furukawa; Kyoji Sekiguchi; Yasushi Ikarashi; Yukitsuka Kudo; Makoto Higuchi; Takaomi C Saido; Sumihiro Maeda; Akihiko Takashima; Masahiko Hara; Nobuo Yaegashi; Yoshio Kase; Hiroyuki Arai
A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo.
Journal of neurochemistry 2009;109(6):1648-57.
2006: M He; T Ohrui; M Maruyama; N Tomita; K Nakayama; Makoto Higuchi; K Furukawa; Hiroyuki Arai
ACE activity in CSF of patients with mild cognitive impairment and Alzheimer disease.
Neurology 2006;67(7):1309-10.
2005: Masahiro Maruyama; Makoto Higuchi; Yoshie Takaki; Yukio Matsuba; Haruko Tanji; Miyako Nemoto; Naoki Tomita; Toshifumi Matsui; Nobuhisa Iwata; Hiroaki Mizukami; Shin-ichi Muramatsu; Keiya Ozawa; Takaomi C Saido; Hiroyuki Arai; Hidetada Sasaki
Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease.
Annals of neurology 2005;57(6):832-42.
2002: XiaSheng Hu; Nobuyuki Okamura; Hiroyuki Arai; Makoto Higuchi; Masahiro Maruyama; Masatoshi Itoh; Keiichro Yamaguchi; Hidetada Sasaki
Neuroanatomical correlates of low body weight in Alzheimer's disease: a PET study.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(7-8):1285-9.
2002: Nobuyuki Okamura; Hiroyuki Arai; Masahiro Maruyama; Makoto Higuchi; Toshifumi Matsui; Haruko Tanji; Takashi Seki; Hisao Hirai; Hiroshi Chiba; Masatoshi Itoh; Hidetada Sasaki
Combined Analysis of CSF Tau Levels and [(123)I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer's Disease.
The American journal of psychiatry 2002;159(3):474-6.
2001: Masahiro Maruyama; Hiroyuki Arai; M Sugita; Haruko Tanji; Makoto Higuchi; Nobuyuki Okamura; Toshifumi Matsui; Susumu Higuchi; Sachio Matsushita; H Yoshida; Hidetada Sasaki
Cerebrospinal fluid amyloid beta(1-42) levels in the mild cognitive impairment stage of Alzheimer's disease.
Experimental neurology 2001;172(2):433-6.
2001: Nobuyuki Okamura; Hiroyuki Arai; Makoto Higuchi; M Tashiro; Toshifumi Matsui; X S Hu; Atsushi Takeda; M Itoh; Hidetada Sasaki
[18F]FDG-PET study in dementia with Lewy bodies and Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 2001;25(2):447-56.
2000: X S Hu; Nobuyuki Okamura; Hiroyuki Arai; Makoto Higuchi; Toshifumi Matsui; M Tashiro; Mitsutoshi Shinkawa; M Itoh; T Ido; Hidetada Sasaki
18F-fluorodopa PET study of striatal dopamine uptake in the diagnosis of dementia with Lewy bodies.
Neurology 2000;55(10):1575-7.
2000: Makoto Higuchi; M Tashiro; Hiroyuki Arai; Nobuyuki Okamura; S Hara; Susumu Higuchi; M Itoh; R W Shin; John Q Trojanowski; Hidetada Sasaki
Glucose hypometabolism and neuropathological correlates in brains of dementia with Lewy bodies.
Experimental neurology 2000;162(2):247-56.
2000: Makoto Higuchi; K Yanai; Nobuyuki Okamura; K Meguro; Hiroyuki Arai; M Itoh; R Iwata; T Ido; T Watanabe; Hidetada Sasaki
Histamine H(1) receptors in patients with Alzheimer's disease assessed by positron emission tomography.
Neuroscience 2000;99(4):721-9.
1999: Toshifumi Matsui; Makoto Higuchi; Nobuyuki Okamura; Hiroyuki Arai; Hidetada Sasaki
A practical method to predict rate of cognitive decline in mild to moderate Alzheimer's disease.
Neurology 1999;53(9):2208-9.
1997: Makoto Higuchi; Hiroyuki Arai; T Nakagawa; Susumu Higuchi; T Muramatsu; Sachio Matsushita; Y Kosaka; M Itoh; Hidetada Sasaki
Regional cerebral glucose utilization is modulated by the dosage of apolipoprotein E type 4 allele and alpha1-antichymotrypsin type A allele in Alzheimer's disease.
Neuroreport 1997;8(12):2639-43.