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Marielle Hijmans

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

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Chemicals & Drugs

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Cloning, Molecular

Physiology

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Publications

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Katrien Berns; Hugo Horlings; Bryan T. J. Hennessy; Mandy Madiredjo; E Marielle Hijmans; Karin Beelen; Sabine C Linn; Ana M Gonzalez-Angulo; Katherine Stemke-Hale; Michael Hauptmann; Roderick L Beijersbergen; Gordon B Mills; Marc J van de Vijver; René Bernards
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Sebastian M B Nijman; E Marielle Hijmans; Selma El Messaoudi; Miranda M W van Dongen; Claude Sardet; René Bernards
A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.
A Milton; K Luoto; L Ingram; Shonagh Munro; Nicola Logan; A L Graham; Thijn R Brummelkamp; E Marielle Hijmans; René Bernards; Nicholas B La Thangue
A functionally distinct member of the DP family of E2F subunits.

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All Publications

2007: Katrien Berns; Hugo Horlings; Bryan T. J. Hennessy; Mandy Madiredjo; E Marielle Hijmans; Karin Beelen; Sabine C Linn; Ana M Gonzalez-Angulo; Katherine Stemke-Hale; Michael Hauptmann; Roderick L Beijersbergen; Gordon B Mills; Marc J van de Vijver; René Bernards
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Cancer cell 2007;12(4):395-402.
2006: Sebastian M B Nijman; E Marielle Hijmans; Selma El Messaoudi; Miranda M W van Dongen; Claude Sardet; René Bernards
A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.
The Journal of biological chemistry 2006;281(31):21582-7.
2006: A Milton; K Luoto; L Ingram; Shonagh Munro; Nicola Logan; A L Graham; Thijn R Brummelkamp; E Marielle Hijmans; René Bernards; Nicholas B La Thangue
A functionally distinct member of the DP family of E2F subunits.
Oncogene 2006;25(22):3212-8.
2005: Menno P Creyghton; Giulietta Roël; Pieter J A Eichhorn; E Marielle Hijmans; Irma Maurer; Olivier Destrée; René Bernards
PR72, a novel regulator of Wnt signaling required for Naked cuticle function.
Genes & development 2005;19(3):376-86.
2004: Nicola Logan; Laurent Delavaine; Anne Graham; Carmel Reilly; Jon Wilson; Thijn R Brummelkamp; E Marielle Hijmans; René Bernards; Nicholas B La Thangue
E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains.
Oncogene 2004;23(30):5138-50.
2004: Katrien Berns; E Marielle Hijmans; Jasper Mullenders; Thijn R Brummelkamp; Arno Velds; Mike Heimerikx; Ron Kerkhoven; Mandy Madiredjo; Wouter Nijkamp; Britta Weigelt; Reuven Agami; Wei Ge; Guy Cavet; Peter Linsley; Roderick L Beijersbergen; René Bernards
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Nature 2004;428(6981):431-7.
2004: Thijn R Brummelkamp; Katrien Berns; E Marielle Hijmans; Jasper Mullenders; A Fabius; Mike Heimerikx; Arno Velds; Ron Kerkhoven; Mandy Madiredjo; René Bernards; Roderick L Beijersbergen
Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.
Cold Spring Harbor symposia on quantitative biology 2004;69():439-45.
2000: Katrien Berns; E Marielle Hijmans; Eugene Koh; George Q Daley; René Bernards
A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts.
Oncogene 2000;19(29):3330-4.
1999: P Mathijs Voorhoeve; E Marielle Hijmans; René Bernards
Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein.
Oncogene 1999;18(2):515-24.
1998: R M Zwijsen; R S Buckle; E Marielle Hijmans; C J Loomans; René Bernards
Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1.
Genes & development 1998;12(22):3488-98.
1997: Katrien Berns; E Marielle Hijmans; René Bernards
Repression of c-Myc responsive genes in cycling cells causes G1 arrest through reduction of cyclin E/CDK2 kinase activity.
Oncogene 1997;15(11):1347-56.
1996: G Hateboer; E Marielle Hijmans; J B Nooij; S Schlenker; Stefan Jentsch; René Bernards
mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect.
The Journal of biological chemistry 1996;271(42):25906-11.
1996: B Smith-Sørensen; E Marielle Hijmans; R L Beijersbergen; René Bernards
Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.
The Journal of biological chemistry 1996;271(10):5513-8.
1995: Vicky Buck; K E Allen; T Sørensen; A Bybee; E Marielle Hijmans; P Mathijs Voorhoeve; René Bernards; Nicholas B La Thangue
Molecular and functional characterisation of E2F-5, a new member of the E2F family.
Oncogene 1995;11(1):31-8.
1995: E Marielle Hijmans; P Mathijs Voorhoeve; R L Beijersbergen; Laura J van 't Veer; René Bernards
E2F-5, a new E2F family member that interacts with p130 in vivo.
Molecular and cellular biology 1995;15(6):3082-9.
1994: R L Beijersbergen; E Marielle Hijmans; Liang Zhu; René Bernards
Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.
The EMBO journal 1994;13(17):4080-6.