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Denise Hilfiker-Kleiner

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Julie Halkein; Denise Hilfiker-Kleiner; Vincent Lambert; Ludovic Malvaux; Joseph A Martial; Ngoc-Quynh-Nhu Nguyen; Agnes Noel; Melanie Ricke-Hoch; Michaela Scherr; Karen Sliwa; Karolien Castermans; Arash Haghikia; Sebastien P Tabruyn; Marc Thiry; Ingrid Struman
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy.
Raja El Hasnaoui-Saadani; Brigitte Escoubet; Denise Hilfiker-Kleiner; Melanie Hoch; Clément Journé; Dominique Marchant; Mylène Pezet; Isabelle Pham; Aurélien Pichon; P Quidu; Jean-Paul Richalet; Nicolas Voituron; Fabrice Favret
Epo deficiency alters cardiac adaptation to chronic hypoxia.
Lori A Blauwet; Olaf Forster; Denise Hilfiker-Kleiner; Elena Libhaber; Alex Mebazaa; Kemi Tibazarwa; Karen Sliwa
Predictors of outcome in 176 South African patients with peripartum cardiomyopathy.

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2013: Julie Halkein; Denise Hilfiker-Kleiner; Vincent Lambert; Ludovic Malvaux; Joseph A Martial; Ngoc-Quynh-Nhu Nguyen; Agnes Noel; Melanie Ricke-Hoch; Michaela Scherr; Karen Sliwa; Karolien Castermans; Arash Haghikia; Sebastien P Tabruyn; Marc Thiry; Ingrid Struman
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy.
The Journal of clinical investigation 2013;123(5):2143-54.
2013: Raja El Hasnaoui-Saadani; Brigitte Escoubet; Denise Hilfiker-Kleiner; Melanie Hoch; Clément Journé; Dominique Marchant; Mylène Pezet; Isabelle Pham; Aurélien Pichon; P Quidu; Jean-Paul Richalet; Nicolas Voituron; Fabrice Favret
Epo deficiency alters cardiac adaptation to chronic hypoxia.
Respiratory physiology & neurobiology 2013;186(2):146-54.
2013: Lori A Blauwet; Olaf Forster; Denise Hilfiker-Kleiner; Elena Libhaber; Alex Mebazaa; Kemi Tibazarwa; Karen Sliwa
Predictors of outcome in 176 South African patients with peripartum cardiomyopathy.
Heart (British Cardiac Society) 2013;99(5):308-13.
2013: Sandra Eifert; Jeanette Erdmann; Denise Hilfiker-Kleiner
Gendered innovation in cardiovascular science: implementation of sex and gender into clinical and biomedical research.
The Thoracic and cardiovascular surgeon 2013;61(1):4-6.
2012: Denise Hilfiker-Kleiner; Melanie Hoch; Edith Podewski; Ingrid Struman; Karen Sliwa
16-kDa prolactin and bromocriptine in postpartum cardiomyopathy.
Current heart failure reports 2012;9(3):174-82.
2012: Katrin Walenta; Erik B Friedrich; Denise Hilfiker-Kleiner; Ingrid Kindermann; Saida Labidi; Stephan H Schirmer; Viktoria Schwarz; Karen Sliwa; Erich Franz Solomayer; Michael Böhm
Circulating microparticles as indicators of peripartum cardiomyopathy.
European heart journal 2012;33(12):1469-79.
2012: Ian S Patten; Sarosh Rana; Julie S Rhee; Glenn C Rowe; Sajid Shahul; Igor Tudorache; Johann Bauersachs; Suzanne D Burke; Federica del Monte; Caitlin Farrell; Michele R Hacker; Philip Hess; Denise Hilfiker-Kleiner; Cholsoon Jang; S Ananth Karumanchi; Eliyahu V Khankin; Nicole Koulisis; Laura Liu; Feroze Mahmood; John Mitchell; Zoltan Arany
Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
Nature 2012;485(7398):333-8.
2012: Diana Lindner; Katharina Marggraf; Matthias Pauschinger; Heinz-Peter Schultheiss; Carsten Tschöpe; P Moritz Becher; Moritz Hilbrandt; Denise Hilfiker-Kleiner; Karin Klingel; Dirk Westermann
Protective Function of STAT3 in CVB3-Induced Myocarditis.
Cardiology research and practice 2012;2012():437623.
2012: Arne Yndestad; Erik Oie; Øystein Sandanger; Geir Christensen; Christen P Dahl; Jan Kristian Damås; Kenneth Dickstein; Arnt E Fiane; Alexandra Vanessa Finsen; Lars Gullestad; Denise Hilfiker-Kleiner; Cathrine Husberg; John Kjekshus; Martin Lipp; Trine Ranheim; Ivar Sjaastad; Thor Ueland; Leif Erik Vinge; Pål Aukrust
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.
PloS one 2012;7(3):e33038.
2011: Ling Li; Rong Li; Christian Mühlfeld; Bernd Niemann; Ruping Pan; Ying Chen; Denise Hilfiker-Kleiner; Susanne Rohrbach
Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle.
Basic research in cardiology 2011;106(6):1221-34.
2011: Frank Echtermeyer; Andrea Grund; Thomas Harendza; Jörg Heineke; Christine Herzog; Denise Hilfiker-Kleiner; Svenja Hubrich; Jan Larmann; Ralf Lichtinghagen; Anika Lorenz; Martin Mueller; Bernhard Schieffer; Martina Schmitz; Jörg Stypmann; Kai C Wollert; Gregor Theilmeier
Syndecan-4 signalling inhibits apoptosis and controls NFAT activity during myocardial damage and remodelling.
Cardiovascular research 2011;92(1):123-31.
2011: Melanie Hoch; Ewa Missol-Kolka; Michaela Scherr; Karin Schuster-Gossler; Belaid Sekkali; Britta Stapel; Jean-Luc Balligand; Thomas Braun; Helmut Drexler; Matthias Eder; Fabrice Favret; Philipp Fischer; Achim Gossler; Andres Hilfiker; Denise Hilfiker-Kleiner
Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies.
Cell stem cell 2011;9(2):131-43.
2011: Ralph Knöll; Adelino F Leite-Moreira; Peter H Sugden; Guido Tarone; Jean-Luc Balligand; Johann Bauersachs; Denise Hilfiker-Kleiner; Guido Iaccarino
Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC.
European journal of heart failure 2011;13(8):811-9.
2011: Saida Labidi; Denise Hilfiker-Kleiner; Gunnar Klein
Left bundle branch block during pregnancy as a sign of imminent peripartum cardiomyopathy.
European heart journal 2011;32(9):1076.
2011: Arash Haghikia; Ewa Missol-Kolka; Dimitrios Tsikas; Letizia Venturini; Stephanie Brundiers; Mirko Castoldi; Martina U Muckenthaler; Matthias Eder; Britta Stapel; Thomas Thum; Aiden Haghikia; Elisabeth Petrasch-Parwez; Helmut Drexler; Denise Hilfiker-Kleiner; Michaela Scherr
Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes.
European heart journal 2011;32(10):1287-97.
2011: Karen Sliwa; Olaf Forster; Kemi Tibazarwa; Elena Libhaber; Anthony Becker; Anthony Yip; Denise Hilfiker-Kleiner
Long-term outcome of peripartum cardiomyopathy in a population with high seropositivity for human immunodeficiency virus.
International journal of cardiology 2011;147(2):202-8.
2011: Sajoscha A Sorrentino; Carola Doerries; Costantina Manes; Thimoteus Speer; Chantal Dessy; Irina Lobysheva; Wazma Mohmand; Razma Akbar; Ferdinand Bahlmann; Christian Besler; Arnd Schaefer; Denise Hilfiker-Kleiner; Thomas F Lüscher; Jean-Luc Balligand; Helmut Drexler; Ulf Landmesser
Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional β1-blockade.
Journal of the American College of Cardiology 2011;57(5):601-11.
2011: Anne Waehre; Bente Halvorsen; Arne Yndestad; Cathrine Husberg; Ivar Sjaastad; Ståle Nygård; Christen P Dahl; M Shakil Ahmed; Alexandra V Finsen; Henrik Reims; William E Louch; Denise Hilfiker-Kleiner; Leif Erik Vinge; Borghild Roald; Håvard Attramadal; Martin Lipp; Lars Gullestad; Pål Aukrust; Geir Christensen
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload.
PloS one 2011;6(4):e18668.
2011: Thomas Eschenhagen; Thomas Force; Michael S Ewer; Gilles W De Keulenaer; Thomas M Suter; Stefan D Anker; Metin Avkiran; Evandro de Azambuja; Jean-Luc Balligand; Dirk L Brutsaert; Gianluigi Condorelli; Arne Hansen; Stephane Heymans; Joseph A Hill; Emilio Hirsch; Denise Hilfiker-Kleiner; Stefan Janssens; Steven de Jong; Gitte Neubauer; Burkert Pieske; Piotr Ponikowski; Munir Pirmohamed; Mathias Rauchhaus; Douglas Sawyer; Peter H Sugden; Johann Wojta; Faiez Zannad; Ajay M Shah
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.
European journal of heart failure 2011;13(1):1-10.
2011: Arash Haghikia; Britta Stapel; Melanie Hoch; Denise Hilfiker-Kleiner
STAT3 and cardiac remodeling.
Heart failure reviews 2011;16(1):35-47.
2010: Madlen Rother; Stefanie Krohn; Gabriela Kania; Davy Vanhoutte; Andreas Eisenreich; Xiaomin Wang; Dirk Westermann; Kostas Savvatis; Nadine Dannemann; Carsten Skurk; Denise Hilfiker-Kleiner; Toni Cathomen; Henry Fechner; Ursula Rauch; Heinz-Peter Schultheiss; Stephane Heymans; Urs Eriksson; Carmen Scheibenbogen; Wolfgang Poller
Matricellular signaling molecule CCN1 attenuates experimental autoimmune myocarditis by acting as a novel immune cell migration modulator.
Circulation 2010;122(25):2688-98.
2010: Kerstin Boengler; Denise Hilfiker-Kleiner; Gerd Heusch; Rainer Schulz
Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion.
Basic research in cardiology 2010;105(6):771-85.
2010: Hatice Yamac; Insa Bultmann; Karen Sliwa; Denise Hilfiker-Kleiner
Prolactin: a new therapeutic target in peripartum cardiomyopathy.
Heart (British Cardiac Society) 2010;96(17):1352-7.
2010: Karen Sliwa; Denise Hilfiker-Kleiner; Mark C Petrie; Alexandre Mebazaa; Burkert Pieske; Eckhart Buchmann; Vera Regitz-Zagrosek; Maria Schaufelberger; Luigi Tavazzi; Dirk J van Veldhuisen; Hugh Watkins; Ajay J Shah; Petar M Seferovic; Uri Elkayam; Sabine Pankuweit; Zoltan Papp; Frederic Mouquet; John J V McMurray
Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy.
European journal of heart failure 2010;12(8):767-78.
2010: Denise Hilfiker-Kleiner; Praphulla Shukla; Gunnar Klein; Arnd Schaefer; Britta Stapel; Melanie Hoch; Werner Muller; Michaela Scherr; Gregor Theilmeier; Matthias Ernst; Andres Hilfiker; Helmut Drexler
Continuous glycoprotein-130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction.
Circulation 2010;122(2):145-55.
2010: Karen Sliwa; Lori Blauwet; Kemi Tibazarwa; Elena Libhaber; Jan-Peter Smedema; Anthony Becker; John McMurray; Hatice Yamac; Saida Labidi; Ingrid Struman; Ingrid Struhman; Denise Hilfiker-Kleiner
Evaluation of bromocriptine in the treatment of acute severe peripartum cardiomyopathy: a proof-of-concept pilot study.
Circulation 2010;121(13):1465-73.
2010: Antonia Bär; Suzanne E Dorfman; Philipp Fischer; Denise Hilfiker-Kleiner; Serghei Cebotari; Igor Tudorache; Marc Suprunov; Axel Haverich; Andres Hilfiker
The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro.
Cardiovascular research 2010;85(4):806-13.
2010: Gerd Peter Meyer; Saida Labidi; Edith Podewski; Karen Sliwa; Helmut Drexler; Denise Hilfiker-Kleiner
Bromocriptine treatment associated with recovery from peripartum cardiomyopathy in siblings: two case reports.
Journal of medical case reports 2010;4():80.
2009: Sylvia Gunkel; Jörg Heineke; Denise Hilfiker-Kleiner; Ralph Knöll
MLP: a stress sensor goes nuclear.
Journal of molecular and cellular cardiology 2009;47(4):423-5.
2009: Arash Haghikia; Denise Hilfiker-Kleiner
MiRNA-21: a key to controlling the cardiac fibroblast compartment?
Cardiovascular research 2009;82(1):1-3.
2009: Tina Selle; Isabelle Renger; Saida Labidi; Insa Bultmann; Denise Hilfiker-Kleiner
Reviewing peripartum cardiomyopathy: current state of knowledge.
Future cardiology 2009;5(2):175-89.
2009: Stephane Heymans; Emilio Hirsch; Stefan D Anker; Pal Aukrust; Jean-Luc Balligand; Jan Willem Cohen-Tervaert; Helmut Drexler; Gerasimos Filippatos; Stephan B Felix; Lars Gullestad; Denise Hilfiker-Kleiner; Stefan Janssens; Roberto Latini; Gitte Neubauer; Walter J Paulus; Burkert Pieske; Piotr Ponikowski; Blanche Schroen; Heinz-Peter Schultheiss; Carsten Tschöpe; Marc van Bilsen; Faiez Zannad; John McMurray; Ajay M Shah
Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology.
European journal of heart failure 2009;11(2):119-29.
2008: Karen Sliwa; Kemi Tibazarwa; Denise Hilfiker-Kleiner
Management of peripartum cardiomyopathy.
Current heart failure reports 2008;5(4):238-44.
2008: Kerstin Boengler; Denise Hilfiker-Kleiner; Helmut Drexler; Gerd Heusch; Rainer Schulz
The myocardial JAK/STAT pathway: from protection to failure.
Pharmacology & therapeutics 2008;120(2):172-85.
2008: Denise Hilfiker-Kleiner; Elisabeth Schieffer; Gerd Peter Meyer; Edith Podewski; Helmut Drexler
Postpartum cardiomyopathy: a cardiac emergency for gynecologists, general practitioners, internists, pulmonologists, and cardiologists.
Deutsches Ärzteblatt international 2008;105(44):751-6.
2008: Boriana G Jahns; Werner Stein; Denise Hilfiker-Kleiner; Burkert Pieske; Günter Emons
Peripartum cardiomyopathy--a new treatment option by inhibition of prolactin secretion.
American journal of obstetrics and gynecology 2008;199(4):e5-6.
2008: Olaf Forster; Denise Hilfiker-Kleiner; Aftab A Ansari; J Bruce Sundstrom; Elena Libhaber; Winnie Tshani; Anthony Becker; Anthony Yip; Gunnar Klein; Karen Sliwa
Reversal of IFN-gamma, oxLDL and prolactin serum levels correlate with clinical improvement in patients with peripartum cardiomyopathy.
European journal of heart failure 2008;10(9):861-8.
2008: Christian Templin; Daniel Kotlarz; Jörg Faulhaber; Sabine Schnabel; Karsten Grote; Gustavo Salguero; Maren Luchtefeld; Karl-Heinz Hiller; Peter Jakob; Hassan Y Naim; Bernhard Schieffer; Denise Hilfiker-Kleiner; Ulf Landmesser; Florian P Limbourg; Helmut Drexler
Ex vivo expanded hematopoietic progenitor cells improve cardiac function after myocardial infarction: role of beta-catenin transduction and cell dose.
Journal of molecular and cellular cardiology 2008;45(3):394-403.
2008: Denise Hilfiker-Kleiner; Karen Sliwa; Helmut Drexler
Peripartum cardiomyopathy: recent insights in its pathophysiology.
Trends in cardiovascular medicine 2008;18(5):173-9.
2008: Mechthild Westhoff-Bleck; Denise Hilfiker-Kleiner; Hans-Heinrich Günter; E Schieffer; Helmut Drexler
[Management of heart diseases in pregnancy: rheumatic and congenital heart disease, myocardial infarction and post partum cardiomyopathy].
Der Internist 2008;49(7):805-10.
2008: Denise Hilfiker-Kleiner; Ralph Knöll
Disease-modifying mutations in familial hypertrophic cardiomyopathy: complexity from simplicity.
Circulation 2008;117(14):1775-7.
2008: P Fischer; Denise Hilfiker-Kleiner
Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects.
British journal of pharmacology 2008;153 Suppl 1():S414-27.
2008: Kerstin Boengler; Astrid Buechert; Yvonne Heinen; Christin Roeskes; Denise Hilfiker-Kleiner; Gerd Heusch; Rainer Schulz
Cardioprotection by ischemic postconditioning is lost in aged and STAT3-deficient mice.
Circulation research 2008;102(1):131-5.
2007: Denise Hilfiker-Kleiner; Gerd Peter Meyer; Elisabeth Schieffer; Britta Goldmann; Edith Podewski; Ingrid Struman; Philipp Fischer; Helmut Drexler
Recovery from postpartum cardiomyopathy in 2 patients by blocking prolactin release with bromocriptine.
Journal of the American College of Cardiology 2007;50(24):2354-5.
2007: Philipp Fischer; Denise Hilfiker-Kleiner
Survival pathways in hypertrophy and heart failure: the gp130-STAT axis.
Basic research in cardiology 2007;102(5):393-411.
2007: Dieter Fischer; Ulf Landmesser; Stephan Spiekermann; Denise Hilfiker-Kleiner; Marian Hospely; Maja Müller; Rudi Busse; Ingrid Fleming; Helmut Drexler
Cytochrome P450 2C9 is involved in flow-dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure.
European journal of heart failure 2007;9(8):770-5.
2007: Carola Doerries; Karsten Grote; Denise Hilfiker-Kleiner; Maren Luchtefeld; Arnd Schaefer; Steven M Holland; Sajoscha Sorrentino; Costantina Manes; Bernhard Schieffer; Helmut Drexler; Ulf Landmesser
Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.
Circulation research 2007;100(6):894-903.
2007: Denise Hilfiker-Kleiner; Karol Kaminski; Edith Podewski; Tomasz Bonda; Arnd Schaefer; Karen Sliwa; Olaf Forster; Anja Quint; Ulf Landmesser; Carola Doerries; Maren Luchtefeld; Valeria Poli; Michael D Schneider; Jean-Luc Balligand; Fanny Desjardins; Aftab A Ansari; Ingrid Struman; Ngoc Q N Nguyen; Nils H Zschemisch; Gunnar Klein; Gerd Heusch; Rainer Schulz; Andres Hilfiker; Helmut Drexler
A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy.
Cell 2007;128(3):589-600.
2006: Artur Lichtenberg; Igor Tudorache; Serghei Cebotari; Mark Suprunov; Greta Tudorache; Heidi Goerler; Joon-Keun Park; Denise Hilfiker-Kleiner; Stefanie Ringes-Lichtenberg; Matthias Karck; Gudrun Brandes; Andres Hilfiker; Axel Haverich
Preclinical testing of tissue-engineered heart valves re-endothelialized under simulated physiological conditions.
Circulation 2006;114(1 Suppl):I559-65.
2006: Christian Templin; Daniel Kotlarz; Frederik Marquart; Joerg Faulhaber; Vanessa Brendecke; Arnd Schaefer; Dimitrios Tsikas; Tomasz Bonda; Denise Hilfiker-Kleiner; Lars Ohl; Hassan Y Naim; Reinhold Foerster; Helmut Drexler; Florian P Limbourg
Transcoronary delivery of bone marrow cells to the infarcted murine myocardium: feasibility, cellular kinetics, and improvement in cardiac function.
Basic research in cardiology 2006;101(4):301-10.
2006: Denise Hilfiker-Kleiner; Andres Hilfiker; Marc Castellazzi; Kai C Wollert; Christian Trautwein; Heribert Schunkert; Helmut Drexler
JunD attenuates phenylephrine-mediated cardiomyocyte hypertrophy by negatively regulating AP-1 transcriptional activity.
Cardiovascular research 2006;71(1):108-17.
2006: Sabine Connert; Simone Wienand; Cora Thiel; Maria Krikunova; Nataliya Glyvuk; Yaroslav Tsytsyura; Denise Hilfiker-Kleiner; Joerg Walter Bartsch; Jurgen Klingauf; Jürgen Wienands
SH3P7/mAbp1 deficiency leads to tissue and behavioral abnormalities and impaired vesicle transport.
The EMBO journal 2006;25(8):1611-22.
2006: Karen Sliwa; Olaf Förster; Elena Libhaber; James D Fett; Jay Bruce Sundstrom; Denise Hilfiker-Kleiner; Aftab A Ansari
Peripartum cardiomyopathy: inflammatory markers as predictors of outcome in 100 prospectively studied patients.
European heart journal 2006;27(4):441-6.
2005: Arnd Schaefer; Gerd Peter Meyer; Denise Hilfiker-Kleiner; Birgit Brand; Helmut Drexler; Gunnar Klein
Evaluation of Tissue Doppler Tei index for global left ventricular function in mice after myocardial infarction: comparison with Pulsed Doppler Tei index.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2005;6(5):367-75.
2005: Denise Hilfiker-Kleiner; Andres Hilfiker; Karol Kaminski; Arnd Schaefer; Joon-Keun Park; Kim Michel; Anja Quint; moshe yaniv; Jonathan B Weitzman; Helmut Drexler
Lack of JunD promotes pressure overload-induced apoptosis, hypertrophic growth, and angiogenesis in the heart.
Circulation 2005;112(10):1470-7.
2005: Arnd Schaefer; Gerd Peter Meyer; Birgit Brand; Denise Hilfiker-Kleiner; Helmut Drexler; Gunnar Klein
Effects of anesthesia on diastolic function in mice assessed by echocardiography.
Echocardiography (Mount Kisco, N.Y.) 2005;22(8):665-70.
2005: Florian P Limbourg; Stefanie Ringes-Lichtenberg; Arnd Schaefer; Christoph Jacoby; Yasmin Mehraein; Mark D Jäger; Anne Limbourg; Martin Fuchs; Gunnar Klein; Matthias Ballmaier; Hans J Schlitt; Juergen Schrader; Denise Hilfiker-Kleiner; Helmut Drexler
Haematopoietic stem cells improve cardiac function after infarction without permanent cardiac engraftment.
European journal of heart failure 2005;7(5):722-9.
2005: Denise Hilfiker-Kleiner; Andres Hilfiker; Helmut Drexler
Many good reasons to have STAT3 in the heart.
Pharmacology & therapeutics 2005;107(1):131-7.
2005: Denise Hilfiker-Kleiner; Anne Limbourg; Helmut Drexler
STAT3-mediated activation of myocardial capillary growth.
Trends in cardiovascular medicine 2005;15(4):152-7.
2005: Gunnar Klein; Arnd Schaefer; Denise Hilfiker-Kleiner; Dagmar Oppermann; Praphulla Shukla; Anja Quint; Edith Podewski; Andres Hilfiker; Frank Schröder; Michael Leitges; Helmut Drexler
Increased collagen deposition and diastolic dysfunction but preserved myocardial hypertrophy after pressure overload in mice lacking PKCepsilon.
Circulation research 2005;96(7):748-55.
2005: Jörg Heineke; Hartmut Ruetten; Christian Willenbockel; Sandra C Gross; Marian Naguib; Arnd Schaefer; Tibor Kempf; Denise Hilfiker-Kleiner; Pico Caroni; Theresia Kraft; Robert A Kaiser; Jeffery D Molkentin; Helmut Drexler; Kai C Wollert
Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1655-60.
2004: Karsten Grote; Udo Bavendiek; Christina Grothusen; Inna Flach; Denise Hilfiker-Kleiner; Helmut Drexler; Bernhard Schieffer
Stretch-inducible expression of the angiogenic factor CCN1 in vascular smooth muscle cells is mediated by Egr-1.
The Journal of biological chemistry 2004;279(53):55675-81.
2004: Bernhard Schieffer; Tina Selle; Andres Hilfiker; Denise Hilfiker-Kleiner; Karsten Grote; Uwe J F Tietge; Christian Trautwein; Maren Luchtefeld; Christian Schmittkamp; Sylvia Heeneman; Mat J A P Daemen; Helmut Drexler
Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis.
Circulation 2004;110(22):3493-500.
2004: Niels Engberding; Stephan Spiekermann; Arnd Schaefer; André Heineke; Antje Wiencke; Maja Müller; Martin Fuchs; Denise Hilfiker-Kleiner; Burkhard Hornig; Helmut Drexler; Ulf Landmesser
Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug?
Circulation 2004;110(15):2175-9.
2004: Ulf Landmesser; Niels Engberding; Ferdinand H Bahlmann; Arnd Schaefer; Antje Wiencke; Andre Heineke; Stephan Spiekermann; Denise Hilfiker-Kleiner; Christian Templin; Daniel Kotlarz; Maja Mueller; Martin Fuchs; Burkhard Hornig; Hermann Haller; Helmut Drexler
Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase.
Circulation 2004;110(14):1933-9.
2004: Denise Hilfiker-Kleiner; Andres Hilfiker; Martin Fuchs; Karol Kaminski; Arnd Schaefer; Bernhard Schieffer; Anja Hillmer; Andreas Schmiedl; Zhaoping Ding; Edith Podewski; Eva Podewski; Valeria Poli; Michael D Schneider; Rainer Schulz; Joon-Keun Park; Kai C Wollert; Helmut Drexler
Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury.
Circulation research 2004;95(2):187-95.
2004: Denise Hilfiker-Kleiner; Karol Kaminski; Agnieszka Kaminska; Martin Fuchs; Gunnar Klein; Edith Podewski; Karsten Grote; Ioulia Kiian; Kai C Wollert; Andres Hilfiker; Helmut Drexler
Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation.
Circulation 2004;109(18):2227-33.
2004: Monika Hediger; Géza Burghardt; Christina Siegenthaler; Nathalie Buser; Denise Hilfiker-Kleiner; Andreas Dübendorfer; Daniel Bopp
Sex determination in Drosophila melanogaster and Musca domestica converges at the level of the terminal regulator doublesex.
Development genes and evolution 2004;214(1):29-42.
2003: Martin Fuchs; Andres Hilfiker; Karol Kaminski; Denise Hilfiker-Kleiner; Zeynep Guener; Gunnar Klein; Edith Podewski; Bernhard Schieffer; Stefan Rose-John; Helmut Drexler
Role of interleukin-6 for LV remodeling and survival after experimental myocardial infarction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(14):2118-20.
2003: Edith Podewski; Denise Hilfiker-Kleiner; Andres Hilfiker; Henning Morawietz; Artur Lichtenberg; Kai C Wollert; Helmut Drexler
Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy.
Circulation 2003;107(6):798-802.
2002: Denise Hilfiker-Kleiner; Helmut Drexler
ACE inhibition improves cardiac force generation after myocardial infarction.
Journal of molecular and cellular cardiology 2002;34(9):1127-30.
2002: Andres Hilfiker; Denise Hilfiker-Kleiner; Martin Fuchs; Karol Kaminski; Artur Lichtenberg; Hermann-Josef Rothkötter; Bernhard Schieffer; Helmut Drexler
Expression of CYR61, an angiogenic immediate early gene, in arteriosclerosis and its regulation by angiotensin II.
Circulation 2002;106(2):254-60.
2002: Denise Hilfiker-Kleiner; Andres Hilfiker; Bernhard Schieffer; David Engel; Douglas L Mann; Kai C Wollert; Helmut Drexler
TNFalpha decreases alphaMHC expression by a NO mediated pathway: role of E-box transcription factors for cardiomyocyte specific gene regulation.
Cardiovascular research 2002;53(2):460-9.
2000: Bernhard Schieffer; Maren Luchtefeld; S Braun; Andres Hilfiker; Denise Hilfiker-Kleiner; Helmut Drexler
Role of NAD(P)H oxidase in angiotensin II-induced JAK/STAT signaling and cytokine induction.
Circulation research 2000;87(12):1195-201.
2000: Bernhard Schieffer; E Schieffer; Denise Hilfiker-Kleiner; Andres Hilfiker; Petri Kovanen; M Kaartinen; J Nussberger; Wolfgang Harringer; Helmut Drexler
Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability.
Circulation 2000;101(12):1372-8.
1998: Monika Hediger; A D Minet; Markus Niessen; R Schmidt; Denise Hilfiker-Kleiner; S Cakir; Rolf Nöthiger; Andreas Dübendorfer
The male-determining activity on the Y chromosome of the housefly (Musca domestica L.) consists of separable elements.
Genetics 1998;150(2):651-61.
1998: M Meise; Denise Hilfiker-Kleiner; Andreas Dübendorfer; C Brunner; Rolf Nöthiger; Daniel Bopp
Sex-lethal, the master sex-determining gene in Drosophila, is not sex-specifically regulated in Musca domestica.
Development (Cambridge, England) 1998;125(8):1487-94.
1997: Andres Hilfiker; Denise Hilfiker-Kleiner; Antonio Pannuti; John C Lucchesi
mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila.
The EMBO journal 1997;16(8):2054-60.
1994: Denise Hilfiker-Kleiner; Andreas Dübendorfer; A Hilfiker; Rolf Nöthiger
Genetic control of sex determination in the germ line and soma of the housefly, Musca domestica.
Development (Cambridge, England) 1994;120(9):2531-8.
1993: Denise Hilfiker-Kleiner; Andreas Dübendorfer; A Hilfiker; Rolf Nöthiger
Developmental analysis of two sex-determining genes, M and F, in the housefly, Musca domestica.
Genetics 1993;134(4):1187-94.