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Ann Hill

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Lila A Farrington; Finn E Grey; Ann B Hill; Tameka A Smith; Christopher M Snyder
Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection.
Christopher M Snyder; Jane E Allan; Elizabeth L Bonnett; Kathy S Cho; Ann B Hill
Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.
Timothy E Schlub; Joseph C Sun; Senta M Walton; Laurent Brossay; Ann B Hill; Michael W Munks; Annette Oxenius; Amelia K Pinto; Scott H Robbins; Miles P Davenport
Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection.

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All Publications

2013: Lila A Farrington; Finn E Grey; Ann B Hill; Tameka A Smith; Christopher M Snyder
Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3410-6.
2011: Christopher M Snyder; Jane E Allan; Elizabeth L Bonnett; Kathy S Cho; Ann B Hill
Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.
PLoS pathogens 2011;7(10):e1002295.
2011: Timothy E Schlub; Joseph C Sun; Senta M Walton; Laurent Brossay; Ann B Hill; Michael W Munks; Annette Oxenius; Amelia K Pinto; Scott H Robbins; Miles P Davenport
Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(3):1385-92.
2010: Christopher M Snyder; Jane E Allan; Elizabeth L Bonnett; Carmen M Doom; Ann B Hill
Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells.
PloS one 2010;5(3):e9681.
2009: Carmen Doom; Holly M Turula; Ann B Hill
Investigation of the impact of the common animal facility contaminant murine norovirus on experimental murine cytomegalovirus infection.
Virology 2009;392(2):153-61.
2009: Christopher M Snyder; Andrea Loewendorf; Elizabeth L Bonnett; Michael Croft; Chris A Benedict; Ann B Hill
CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):3932-41.
2009: Agnieszka Kielczewska; Michal Pyzik; Tianhe Sun; Astrid Krmpotic; Melissa B Lodoen; Michael W Munks; Marina Babic; Ann B Hill; Ulrich H Koszinowski; Stipan Jonjic; Lewis L Lanier; Silvia M Vidal
Ly49P recognition of cytomegalovirus-infected cells expressing H2-Dk and CMV-encoded m04 correlates with the NK cell antiviral response.
The Journal of experimental medicine 2009;206(3):515-23.
2008: Christopher M Snyder; Kathy Cho; Elizabeth L Bonnett; Serani van Dommelen; Geoffrey R Shellam; Ann B Hill
Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells.
Immunity 2008;29(4):650-9.
2008: Senta M Walton; Philippe Wyrsch; Michael W Munks; Albert Zimmermann; Hartmut Hengel; Ann B Hill; Annette Oxenius
The dynamics of mouse cytomegalovirus-specific CD4 T cell responses during acute and latent infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1128-34.
2008: Rafaela Holtappels; Christian O Simon; Michael W Munks; Doris Thomas; Petra Deegen; Birgit Kühnapfel; Torsten Däubner; Simone F Emde; Jürgen Podlech; Natascha K A Grzimek; Silke A Oehrlein-Karpi; Ann B Hill; Matthias J Reddehase
Subdominant CD8 T-cell epitopes account for protection against cytomegalovirus independent of immunodomination.
Journal of virology 2008;82(12):5781-96.
2008: Carmen Doom; Ann B Hill
MHC class I immune evasion in MCMV infection.
Medical microbiology and immunology 2008;197(2):191-204.
2008: Kathy Cho; Ann B Hill
T cell acquisition of APC membrane can impact interpretation of adoptive transfer experiments using CD45 congenic mouse strains.
Journal of immunological methods 2008;330(1-2):137-45.
2007: Amelia K Pinto; Amanda M Jamieson; David H Raulet; Ann B Hill
The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the Murine cytomegalovirus immunoevasin m152/gp40.
Journal of virology 2007;81(22):12564-71.
2007: Christopher S Morello; Laura A Kelley; Michael W Munks; Ann B Hill; Deborah H Spector
DNA immunization using highly conserved murine cytomegalovirus genes encoding homologs of human cytomegalovirus UL54 (DNA polymerase) and UL105 (helicase) elicits strong CD8 T-cell responses and is protective against systemic challenge.
Journal of virology 2007;81(14):7766-75.
2007: Michael W Munks; Amelia K Pinto; Carmen Doom; Ann B Hill
Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7235-41.
2006: Amelia K Pinto; Michael W Munks; Ulrich H Koszinowski; Ann B Hill
Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):3225-34.
2006: Michael W Munks; Kathy Cho; Amelia K Pinto; Sophie Sierro; Paul Klenerman; Ann B Hill
Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):450-8.
2006: Xiuju Lu; Daniel G Kavanagh; Ann B Hill
Cellular and molecular requirements for association of the murine cytomegalovirus protein m4/gp34 with major histocompatibility complex class I molecules.
Journal of virology 2006;80(12):6048-55.
2006: Xiuju Lu; Amelia K Pinto; Ann M Kelly; Kathy Cho; Ann B Hill
Murine cytomegalovirus interference with antigen presentation contributes to the inability of CD8 T cells to control virus in the salivary gland.
Journal of virology 2006;80(8):4200-2.
2006: Michael W Munks; Marielle C Gold; Allison L Zajac; Carmen Doom; Christopher S Morello; Deborah H Spector; Ann B Hill
Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3760-6.
2005: Paul Klenerman; Ann B Hill
T cells and viral persistence: lessons from diverse infections.
Nature immunology 2005;6(9):873-9.
2005: Amelia K Pinto; Ann B Hill
Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus.
Viral immunology 2005;18(3):434-44.
2004: Michael W Munks; Dan V Mourich; Robert S Mittler; Andrew D Weinberg; Ann B Hill
4-1BB and OX40 stimulation enhance CD8 and CD4 T-cell responses to a DNA prime, poxvirus boost vaccine.
Immunology 2004;112(4):559-66.
2004: Marielle C Gold; Michael W Munks; Markus Wagner; Christopher W McMahon; Ann Kelly; Daniel G Kavanagh; Mark K Slifka; Ulrich H Koszinowski; David H Raulet; Ann B Hill
Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6944-53.
2003: Dan V Mourich; Michael W Munks; Jason C Murphy; Richard C Willson; Ann B Hill
Spermine compaction is an efficient and economical method of producing vaccination-grade DNA.
Journal of immunological methods 2003;274(1-2):257-64.
2003: Diane M LoPiccolo; Marielle C Gold; Daniel G Kavanagh; Markus Wagner; Ulrich H Koszinowski; Ann B Hill
Effective inhibition of K(b)- and D(b)-restricted antigen presentation in primary macrophages by murine cytomegalovirus.
Journal of virology 2003;77(1):301-8.
2002: jon yewdell; Ann B Hill
Viral interference with antigen presentation.
Nature immunology 2002;3(11):1019-25.
2002: Marielle C Gold; Michael W Munks; Markus Wagner; Ulrich H Koszinowski; Ann B Hill; Steven P Fling
The murine cytomegalovirus immunomodulatory gene m152 prevents recognition of infected cells by M45-specific CTL but does not alter the immunodominance of the M45-specific CD8 T cell response in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):359-65.
2002: Hisashi Arase; Edward Mocarski; Ann E Campbell; Ann B Hill; Lewis L Lanier
Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors.
Science (New York, N.Y.) 2002;296(5571):1323-6.
2002: Bin Gao; Raju Adhikari; Mark Howarth; Kimitoshi Nakamura; Marielle C Gold; Ann B Hill; Rai Knee; Marek Michalak; Tim Elliott
Assembly and antigen-presenting function of MHC class I molecules in cells lacking the ER chaperone calreticulin.
Immunity 2002;16(1):99-109.
2001: Daniel G Kavanagh; Marielle C Gold; Markus Wagner; Ulrich H Koszinowski; Ann B Hill
The multiple immune-evasion genes of murine cytomegalovirus are not redundant: m4 and m152 inhibit antigen presentation in a complementary and cooperative fashion.
The Journal of experimental medicine 2001;194(7):967-78.
2001: Daniel G Kavanagh; Ulrich H Koszinowski; Ann B Hill
The murine cytomegalovirus immune evasion protein m4/gp34 forms biochemically distinct complexes with class I MHC at the cell surface and in a pre-Golgi compartment.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3894-902.
2001: Daniel G Kavanagh; Ann B Hill
Evasion of cytotoxic T lymphocytes by murine cytomegalovirus.
Seminars in immunology 2001;13(1):19-26.
1998: Susanne Hinkley; Ann B Hill; Subramaniam Srikumaran
Bovine herpesvirus-1 infection affects the peptide transport activity in bovine cells.
Virus research 1998;53(1):91-6.
1998: David C Johnson; Ann B Hill
Herpesvirus evasion of the immune system.
Current topics in microbiology and immunology 1998;232():149-77.
1997: EJ Wiertz; Ann B Hill; Domenico Tortorella; H Ploegh
Cytomegaloviruses use multiple mechanisms to elude the host immune response.
Immunology letters 1997;57(1-3):213-6.
1997: B Galocha; Ann B Hill; B C Barnett; Aidan Dolan; A Raimondi; R F Cook; J Brunner; Duncan J McGeoch; Hidde L Ploegh
The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues.
The Journal of experimental medicine 1997;185(9):1565-72.
1997: M F Kleijnen; JB Huppa; Pero Lucin; S Mukherjee; HE Farrell; Ann E Campbell; Ulrich H Koszinowski; Ann B Hill; Hidde L Ploegh
A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface.
The EMBO journal 1997;16(4):685-94.
1996: Ann B Hill
Mechanisms of interference with the MHC class I-restricted pathway of antigen presentation by herpesviruses.
Immunology and cell biology 1996;74(6):523-6.
1996: D J Schust; Ann B Hill; Hidde L Ploegh
Herpes simplex virus blocks intracellular transport of HLA-G in placentally derived human cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3375-80.
1996: Roman A Tomazin; Ann B Hill; P Jugovic; I York; P van Endert; Hidde L Ploegh; David W Andrews; David C Johnson
Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP.
The EMBO journal 1996;15(13):3256-66.
1995: Ann B Hill; P Jugovic; I York; G Russ; J Bennink; jon yewdell; Hidde L Ploegh; David C Johnson
Herpes simplex virus turns off the TAP to evade host immunity.
Nature 1995;375(6530):411-5.
1995: H Tomiyama; Y Takamiya; Ann B Hill; V Cerundolo; A Kelly; K Egawa; J Trowsdale; M Takiguchi
Isolation of a human allo-peptide presented by HLA-B51 molecules.
International immunology 1995;7(6):905-9.
1995: Ann B Hill; S P Lee; JS Haurum; N Murray; Q Y Yao; M Rowe; N Signoret; Alan B Rickinson; Andrew J McMichael
Class I major histocompatibility complex-restricted cytotoxic T lymphocytes specific for Epstein-Barr virus (EBV)-transformed B lymphoblastoid cell lines against which they were raised.
The Journal of experimental medicine 1995;181(6):2221-8.
1995: Ann B Hill; Hidde L Ploegh
Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):341-3.
1995: Ann B Hill; A Worth; Tim Elliott; S Rowland-Jones; J Brooks; Alan B Rickinson; Andrew McMichael
Characterization of two Epstein-Barr virus epitopes restricted by HLA-B7.
European journal of immunology 1995;25(1):18-24.
1994: Ann B Hill; B C Barnett; Andrew J McMichael; Duncan J McGeoch
HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2736-41.
1993: M J Browning; P Krausa; Andrew Rowan; Ann B Hill; D C Bicknell; JG Bodmer; W F Bodmer
Loss of human leukocyte antigen expression on colorectal tumor cell lines: implications for anti-tumor immunity and immunotherapy.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(3):163-8.
1993: S L Rowland-Jones; S H Powis; J Sutton; I Mockridge; F M Gotch; N Murray; Ann B Hill; W M Rosenberg; J Trowsdale; Andrew J McMichael
An antigen processing polymorphism revealed by HLA-B8-restricted cytotoxic T lymphocytes which does not correlate with TAP gene polymorphism.
European journal of immunology 1993;23(8):1999-2004.
1993: Ann B Hill; Arno Müllbacher; Robert V Blanden
Ir1 genes, peripheral cross-tolerance and immunodominance in MHC class I-restricted T-cell responses: an old quagmire revisited.
Immunological reviews 1993;133():75-91.
1993: Ann B Hill; M Takiguchi; Andrew McMichael
Different rates of HLA class I molecule assembly which are determined by amino acid sequence in the alpha 2 domain.
Immunogenetics 1993;37(2):95-101.
1992: Ann B Hill; Robert V Blanden; C R Parrish; Arno Müllbacher
Restimulated memory Tc cells have a higher apparent avidity of interaction with targets than primary virus-immune Tc cells as indicated by anti-CD8 blocking.
Immunology and cell biology 1992;70 ( Pt 4)():259-65.
1992: LG Kaklamanis; K C Gatter; Ann B Hill; Neil Mortensen; Adrian L Harris; P Krausa; Andrew McMichael; JG Bodmer; W F Bodmer
Loss of HLA class-I alleles, heavy chains and beta 2-microglobulin in colorectal cancer.
International journal of cancer. Journal international du cancer 1992;51(3):379-85.
1992: Ann B Hill; Arno Müllbacher; C Parrish; G Coia; E G Westaway; Robert V Blanden
Broad cross-reactivity with marked fine specificity in the cytotoxic T cell response to flaviviruses.
The Journal of general virology 1992;73 ( Pt 5)():1115-23.
1992: L Pazmany; S Rowland-Jones; S Huet; Ann B Hill; J Sutton; R Murray; J Brooks; Andrew McMichael
Genetic modulation of antigen presentation by HLA-B27 molecules.
The Journal of experimental medicine 1992;175(2):361-9.
1992: LG Kaklamanis; Ann B Hill
MHC loss in colorectal tumours: evidence for immunoselection?
Cancer surveys 1992;13():155-71.
1991: Arno Müllbacher; Ann B Hill; Robert V Blanden; William B Cowden; Nicholas J C King; R T Hla
Alloreactive cytotoxic T cells recognize MHC class I antigen without peptide specificity.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(6):1765-72.
1991: C R Parrish; G Coia; Ann B Hill; Arno Müllbacher; E G Westaway; Robert V Blanden
Preliminary analysis of murine cytotoxic T cell responses to the proteins of the flavivirus Kunjin using vaccinia virus expression.
The Journal of general virology 1991;72 ( Pt 7)():1645-53.
1987: Robert V Blanden; P D Hodgkin; Ann B Hill; V G Sinickas; Arno Müllbacher
Quantitative considerations of T-cell activation and self tolerance.
Immunological reviews 1987;98():75-93.