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Adnane Achour

Research Profile

Procedures

X Ray Crystallography

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

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Protein Binding

Anatomy

Killer Cells, Natural

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Publications

TOP 3
Davide Angeletti; Susanna M Bächle; Karin Blomqvist; María Del Pilar Quintana; Tatyana Sandalova; Alan Sawyer; Mats Wahlgren; Adnane Achour; Tahmina Akhter; Letusa Albrecht; Kirsten Moll
Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.
Chaithanya Madhurantakam; Tatyana Sandalova; John R Webb; Adil D Duru; Adnane Achour
Inflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complex.
Marie Borggren; Melissa J Churchill; Eva Maria Fenyö; Paul R Gorry; Anders Karlsson; Johanna Repits; Jasminka Sterjovski; Hannes Uchtenhagen; Adnane Achour; Jan Albert; Marianne Jansson
Increased sensitivity to broadly neutralizing antibodies of end-stage disease R5 HIV-1 correlates with evolution in Env glycosylation and charge.

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All Publications

2012: Davide Angeletti; Susanna M Bächle; Karin Blomqvist; María Del Pilar Quintana; Tatyana Sandalova; Alan Sawyer; Mats Wahlgren; Adnane Achour; Tahmina Akhter; Letusa Albrecht; Kirsten Moll
Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.
PloS one 2012;7(12):e50758.
2012: Chaithanya Madhurantakam; Tatyana Sandalova; John R Webb; Adil D Duru; Adnane Achour
Inflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complex.
PloS one 2012;7(3):e32805.
2011: Marie Borggren; Melissa J Churchill; Eva Maria Fenyö; Paul R Gorry; Anders Karlsson; Johanna Repits; Jasminka Sterjovski; Hannes Uchtenhagen; Adnane Achour; Jan Albert; Marianne Jansson
Increased sensitivity to broadly neutralizing antibodies of end-stage disease R5 HIV-1 correlates with evolution in Env glycosylation and charge.
PloS one 2011;6(6):e20135.
2010: Linn S Strandberg; Aurelie Ambrosi; Maja Jagodic; Vijole Dzikaite; Peter Janson; Mohsen Khademi; Stina Salomonsson; Lars Ottosson; Robert Klauninger; Ulrika Adén; Sven-Erik Sonesson; Maria Sunnerhagen; Katrien L de Graaf; Vijay K Kuchroo; Adnane Achour; Ola Winqvist; Tomas Olsson; Marie Wahren-Herlenius
Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(6):3574-82.
2010: Chaithanya Madhurantakam; Ola B Nilsson; Hannes Uchtenhagen; Jon Konradsen; Tiiu Saarne; Erik Högbom; Tatyana Sandalova; Hans Grönlund; Adnane Achour
Crystal structure of the dog lipocalin allergen Can f 2: implications for cross-reactivity to the cat allergen Fel d 4.
Journal of molecular biology 2010;401(1):68-83.
2010: Petter Brodin; Tadepally Lakshmikanth; Ramit Mehr; MH Johansson; Adil Doganay Duru; Adnane Achour; Mali Salmon-Divon; Klas Kärre; Petter Höglund; Sofia Johansson
Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice.
PloS one 2010;5(10):.
2010: Gülşen Ozkaya Sahin; Emma J Bowles; Joe Parker; Hannes Uchtenhagen; Enas Sheik-Khalil; Stephen Taylor; Oliver G Pybus; Barbro Mäkitalo; Lilian Walther-Jallow; Mats Spångberg; Rigmor Thorstensson; Adnane Achour; Eva Maria Fenyö; Guillaume B E Stewart-Jones; Anna-Lena Spetz
Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.
PLoS pathogens 2010;6(9):e1001084.
2009: Fabrice Neiers; Chaithanya Madhurantakam; Stefan Fälker; Clothilde Manzano; Andrea Dessen; Staffan Normark; Birgitta Henriques Normark; Adnane Achour
Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity.
Journal of molecular biology 2009;393(3):704-16.
2009: Marianne J B van Stipdonk; Daniel Badia-Martinez; Marjolein Sluijter; Rienk Offringa; Thorbald van Hall; Adnane Achour
Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.
Cancer research 2009;69(19):7784-92.
2009: Hannes Uchtenhagen; Samer Sourial; Rosmarie Friemann; Mariethe Ehnlund; Anna-Lena Spetz; Robert A Harris; Chaithanya Madhurantakam; Adnane Achour
Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 7):705-8.
2009: Chaithanya Madhurantakam; Ola B Nilsson; Klas Jönsson; Hans Grönlund; Adnane Achour
Production, crystallization and preliminary X-ray diffraction analysis of the allergen Can f 2 from Canis familiaris.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 5):467-71.
2008: Monica Vilhelmsson; Adam Woolf glaser; Daniel Badia Martinez; Margit Schmidt; Catharina Johansson; Claudio Rhyner; Kurt D Berndt; Annika Scheynius; Reto Crameri; Adnane Achour; Arezou Zargari
Mutational analysis of amino acid residues involved in IgE-binding to the Malassezia sympodialis allergen Mala s 11.
Molecular immunology 2008;46(2):294-303.
2008: Johanna Repits; Jasminka Sterjovski; Daniel Badia-Martinez; Mattias Mild; Lachlan Gray; Melissa J Churchill; Damian F J Purcell; Anders Karlsson; Jan Albert; Eva Maria Fenyö; Adnane Achour; Paul R Gorry; Marianne Jansson
Primary HIV-1 R5 isolates from end-stage disease display enhanced viral fitness in parallel with increased gp120 net charge.
Virology 2008;379(1):125-34.
2008: Claudia S Wagner; Hans-Gustaf Ljunggren; Adnane Achour
Immune modulation by the human cytomegalovirus-encoded molecule UL18, a mystery yet to be solved.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):19-24.
2008: Claudia S Wagner; Lilian Walther-Jallow; Eva Buentke; Hans-Gustaf Ljunggren; Adnane Achour; Benedict J Chambers
Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells.
Journal of leukocyte biology 2008;83(1):56-63.
2007: Claudia S Wagner; Alexander Rölle; David Cosman; Hans-Gustaf Ljunggren; Kurt D Berndt; Adnane Achour
Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1.
Journal of molecular biology 2007;373(3):695-705.
2007: Liselotte Kaiser; Tanja Cirkovic Velickovic; Daniel Badia-Martinez; Justus Adedoyin; Sarah Thunberg; Dan Hallén; Kurt Berndt; Hans Grönlund; Guro Gafvelin; Marianne van Hage; Adnane Achour
Structural characterization of the tetrameric form of the major cat allergen Fel d 1.
Journal of molecular biology 2007;370(4):714-27.
2007: Maja Wållberg; Jonas Bergquist; Adnane Achour; Esther Breij; Robert A Harris
Malondialdehyde modification of myelin oligodendrocyte glycoprotein leads to increased immunogenicity and encephalitogenicity.
European journal of immunology 2007;37(7):1986-95.
2007: Monica Vilhelmsson; Arezou Zargari; Reto Crameri; Omid Rasool; Adnane Achour; Annika Scheynius; B Martin Hallberg
Crystal structure of the major Malassezia sympodialis allergen Mala s 1 reveals a beta-propeller fold: a novel fold among allergens.
Journal of molecular biology 2007;369(4):1079-86.
2006: Samer Sourial; Charlotta Nilsson; Anette Wärnmark; Adnane Achour; Robert A Harris
Deletion of the V1/V2 region does not increase the accessibility of the V3 region of recombinant gp125.
Current HIV research 2006;4(2):229-37.
2006: Claudia Thilo; Peter Berglund; Steven E Applequist; jon yewdell; Hans-Gustaf Ljunggren; Adnane Achour
Dissection of the interaction of the human cytomegalovirus-derived US2 protein with major histocompatibility complex class I molecules: prominent role of a single arginine residue in human leukocyte antigen-A2.
The Journal of biological chemistry 2006;281(13):8950-7.
2006: Cristina Cerboni; Adnane Achour; Anette Wärnmark; Mehrdad Mousavi-Jazi; Tatyana Sandalova; Mei-Ling Hsu; David Cosman; Klas Kärre; Ennio Carbone
Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j.
European journal of immunology 2006;36(3):732-41.
2006: Adnane Achour; Jakob Michaëlsson; Robert A Harris; Hans-Gustaf Ljunggren; Klas Kärre; Gunter Schneider; Tatyana Sandalova
Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin.
Journal of molecular biology 2006;356(2):382-96.
2006: Monica Vilhelmsson; B Martin Hallberg; Omid Rasool; Arezou Zargari; Annika Scheynius; Adnane Achour
Crystallization and preliminary crystallographic study of the yeast Malassezia sympodialis allergen Mala s 1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 2):97-9.
2005: Tatyana Sandalova; Jakob Michaëlsson; Robert A Harris; Hans-Gustaf Ljunggren; Klas Kärre; Gunter Schneider; Adnane Achour
Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 12):1090-3.
2005: Tatyana Sandalova; Jakob Michaëlsson; Robert A Harris; Jacob Odeberg; Gunter Schneider; Klas Kärre; Adnane Achour
A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.
The Journal of biological chemistry 2005;280(29):27069-75.
2005: Samer Sourial; Anette Wärnmark; Charlotta Nilsson; Ewa Björling; Adnane Achour; Robert A Harris
Cloning, expression, and purification of HIV-2 gp125: A target for HIV vaccination.
Molecular biotechnology 2005;30(2):155-62.
2005: Liselotte Kaiser; Hans Grönlund; Marianne Van Hage-Hamsten; Adnane Achour
Crystallization and preliminary crystallographic data of a Fel d 1 (1+2) construct corresponding to the major allergen from cat.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 2):232-4.
2004: Lucas Malard Velloso; Jakob Michaëlsson; Hans-Gustaf Ljunggren; Gunter Schneider; Adnane Achour
Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5504-11.
2003: Liselotte Kaiser; Hans Grönlund; Tatyana Sandalova; Hans-Gustaf Ljunggren; Marianne Van Hage-Hamsten; Adnane Achour; Gunter Schneider
The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family.
The Journal of biological chemistry 2003;278(39):37730-5.
2003: Liselotte Kaiser; Hans Grönlund; Tatyana Sandalova; Hans-Gustaf Ljunggren; Adnane Achour; Gunter Schneider; Marianne Van Hage-Hamsten
Three-dimensional structure of Fel d 1, the major allergen in cat.
International archives of allergy and immunology 2003;132(1):25-6.
2003: Liselotte Kaiser; Hans Grönlund; Tatyana Sandalova; Hans-Gustaf Ljunggren; Gunter Schneider; Marianne Van Hage-Hamsten; Adnane Achour
Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d 1.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 6):1103-5.
2002: Jakob Michaëlsson; Cristina Teixeira de Matos; Adnane Achour; Lewis L Lanier; Klas Kärre; Kalle Söderström
A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.
The Journal of experimental medicine 2002;196(11):1403-14.
2002: Adnane Achour; Jakob Michaëlsson; Robert A Harris; Jacob Odeberg; Per Grufman; Johan K Sandberg; Victor Levitsky; Klas Kärre; Tatyana Sandalova; Gunter Schneider
A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses.
Immunity 2002;17(6):757-68.
2002: M Waldenström; Adnane Achour; J Michaelsson; Alexander Rölle; Klas Kärre
The role of an exposed loop in the alpha2 domain in the mouse MHC class I H-2Dd molecule for recognition by the monoclonal antibody 34-5-8S and the NK-cell receptor Ly49A.
Scandinavian journal of immunology 2002;55(2):129-39.
2002: Jonas Sundbäck; Adnane Achour; Jakob Michaëlsson; Hannah Lindström; Klas Kärre
NK cell inhibitory receptor Ly-49C residues involved in MHC class I binding.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):793-800.
2001: Jehad Charo; Annemieke Geluk; Maria Sundbäck; B Mirzai; Alexander Diehl; Karl-Johan Malmberg; Adnane Achour; S Huriguchi; Krista E van Meijgaarden; Jan Wouter Drijfhout; Nico J Beekman; Peter van Veelen; Ferry Ossendorp; T H Ottenhoff; Rolf Kiessling
The identification of a common pathogen-specific HLA class I A*0201-restricted cytotoxic T cell epitope encoded within the heat shock protein 65.
European journal of immunology 2001;31(12):3602-11.
2001: Jakob Michaëlsson; Adnane Achour; Alexander Rölle; Klas Kärre
MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7327-34.
2000: J K Sandberg; Ann-Charlotte Boström; Claudia Devito; B Kohleisen; Volker Erfle; Adnane Achour; M Levi; S Schwartz; Klas Kärre; Britta Wahren; Jorma Hinkula
Human immunodeficiency virus type 1 Nef epitopes recognized in HLA-A2 transgenic mice in response to DNA and peptide immunization.
Virology 2000;273(1):112-9.
2000: Johan K Sandberg; L Franksson; Jonas Sundbäck; J Michaelsson; M Petersson; Adnane Achour; Robert P A Wallin; N E Sherman; T Bergman; H Jörnvall; D F Hunt; Rolf Kiessling; Klas Kärre
T cell tolerance based on avidity thresholds rather than complete deletion allows maintenance of maximal repertoire diversity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):25-33.
2000: Jakob Michaëlsson; Adnane Achour; M Salcedo; A Kâse-Sjöström; Jonas Sundbäck; Robert A Harris; Klas Kärre
Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers.
European journal of immunology 2000;30(1):300-7.
1999: L Franksson; Jonas Sundbäck; Adnane Achour; J Bernlind; Rickard Glas; Klas Kärre
Peptide dependency and selectivity of the NK cell inhibitory receptor Ly-49C.
European journal of immunology 1999;29(9):2748-58.
1999: Andreas Mörner; Adnane Achour; Martin Norin; Rigmor Thorstensson; Ewa Björling
Fine characterization of a V3-region neutralizing epitope in human immunodeficiency virus type 2.
Virus research 1999;59(1):49-60.
1999: Pia Skott; Adnane Achour; Martin Norin; Rigmor Thorstensson; Ewa Björling
Characterization of neutralizing sites in the second variable and fourth variable region in gp125 and a conserved region in gp36 of human immunodeficiency virus type 2.
Viral immunology 1999;12(1):79-88.
1999: Adnane Achour; Robert A Harris; K Persson; Jonas Sundbäck; charles sentman; Gunter Schneider; Ylva Lindqvist; Klas Kärre
Murine class I major histocompatibility complex H-2Dd: expression, refolding and crystallization.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 1):260-2.
1998: M Waldenström; Jonas Sundbäck; MY Olsson-Alheim; Adnane Achour; Klas Kärre
Impaired MHC class I (H-2Dd)-mediated protection against Ly-49A+ NK cells after amino acid substitutions in the antigen binding cleft.
European journal of immunology 1998;28(9):2872-81.
1998: Adnane Achour; K Persson; Robert A Harris; Jonas Sundbäck; charles sentman; Ylva Lindqvist; Gunter Schneider; Klas Kärre
The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition.
Immunity 1998;9(2):199-208.
1998: B Fadeel; J Lindberg; Adnane Achour; Francesca Chiodi
A three-dimensional model of the Fas/APO-1 molecule: cross-reactivity of anti-Fas antibodies explained by structural mimicry of antigenic sites.
International immunology 1998;10(2):131-40.