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Kenneth Hillan

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Oligonucleotide Array Sequence Analysis

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Brock A Peters; Zhengyan Kan; Dragan Sebisanovic; Kanan Pujara; Zhiyong Wang; Peter Hong; Bernard Chow; Jeremy Stinson; Victoria E H Carlton; Thinh Q Pham; Howard M Stern; Paul Waring; Kenneth J Hillan; David A Eberhard; Frederic J de Sauvage; Jianbiao Zheng; Malek Faham; Somasekar Seshagiri
Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.
Adrian M Jubb; Sreedevi Chalasani; Gretchen D Frantz; R Smits; Heike Grabsch; V Kavi; Nicola Joanne Maughan; Kenneth J Hillan; Philip Quirke; Hartmut Koeppen
Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia.
Michael Scott; W Glenn McCluggage; Kenneth J Hillan; Peter A Hall; S E Hilary Russell
Altered patterns of transcription of the septin gene, SEPT9, in ovarian tumorigenesis.

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2007: Brock A Peters; Zhengyan Kan; Dragan Sebisanovic; Kanan Pujara; Zhiyong Wang; Peter Hong; Bernard Chow; Jeremy Stinson; Victoria E H Carlton; Thinh Q Pham; Howard M Stern; Paul Waring; Kenneth J Hillan; David A Eberhard; Frederic J de Sauvage; Jianbiao Zheng; Malek Faham; Somasekar Seshagiri
Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection.
Nature methods 2007;4(9):713-5.
2006: Adrian M Jubb; Sreedevi Chalasani; Gretchen D Frantz; R Smits; Heike Grabsch; V Kavi; Nicola Joanne Maughan; Kenneth J Hillan; Philip Quirke; Hartmut Koeppen
Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia.
Oncogene 2006;25(24):3445-57.
2006: Michael Scott; W Glenn McCluggage; Kenneth J Hillan; Peter A Hall; S E Hilary Russell
Altered patterns of transcription of the septin gene, SEPT9, in ovarian tumorigenesis.
International journal of cancer. Journal international du cancer 2006;118(5):1325-9.
2006: Adrian M Jubb; Herbert I Hurwitz; Wei Bai; Eric Holmgren; Patti Tobin; A Steven Guerrero; Fairooz Kabbinavar; Scott N Holden; William F Novotny; Gretchen D Frantz; Kenneth J Hillan; Hartmut Koeppen
Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(2):217-27.
2006: Adrian M Jubb; Thinh Q Pham; Gretchen D Frantz; Franklin Peale; Kenneth J Hillan
Quantitative in situ hybridization of tissue microarrays.
Methods in molecular biology (Clifton, N.J.) 2006;326():255-64.
2005: Peter A Hall; Christopher B Todd; Paula L Hyland; Simon S McDade; Heike Grabsch; Mit Dattani; Kenneth J Hillan; S E Hilary Russell
The septin-binding protein anillin is overexpressed in diverse human tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 1):6780-6.
2005: David A Eberhard; Bruce E Johnson; Lukas C Amler; Audrey D Goddard; Sherry L Heldens; Roy S Herbst; William L Ince; Pasi A Janne; Thomas Januario; David H Johnson; Pam Klein; Vincent A Miller; Michael A Ostland; David A Ramies; Dragan Sebisanovic; Jeremy Stinson; Yu R Zhang; Somasekar Seshagiri; Kenneth J Hillan
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(25):5900-9.
2005: Napoleone Ferrara; Kenneth J Hillan; William F Novotny
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy.
Biochemical and biophysical research communications 2005;333(2):328-35.
2005: Michael Scott; Paula L Hyland; Gordon McGregor; Kenneth J Hillan; S E Hilary Russell; Peter A Hall
Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours.
Oncogene 2005;24(29):4688-700.
2005: William L Ince; Adrian M Jubb; Scott N Holden; Eric Holmgren; Patti Tobin; Meera Sridhar; Herbert I Hurwitz; Fairooz Kabbinavar; William F Novotny; Kenneth J Hillan; Hartmut Koeppen
Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab.
Journal of the National Cancer Institute 2005;97(13):981-9.
2005: Peter A Hall; Kenneth Jung; Kenneth J Hillan; S E Hilary Russell
Expression profiling the human septin gene family.
The Journal of pathology 2005;206(3):269-78.
2005: Lukas C Amler; Audrey D Goddard; Kenneth J Hillan
Predicting clinical benefit in non-small-cell lung cancer patients treated with epidermal growth factor tyrosine kinase inhibitors.
Cold Spring Harbor symposia on quantitative biology 2005;70():483-8.
2004: Yan Zhang; David A Eberhard; Gretchen D Frantz; Patrick Dowd; Thomas D Wu; Yan Zhou; Colin Watanabe; Shiuh-Ming Luoh; Paul Polakis; Kenneth J Hillan; William I Wood; Zemin Zhang
GEPIS--quantitative gene expression profiling in normal and cancer tissues.
Bioinformatics (Oxford, England) 2004;20(15):2390-8.
2004: Napoleone Ferrara; Kenneth J Hillan; Hans-Peter Gerber; William F Novotny
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer.
Nature reviews. Drug discovery 2004;3(5):391-400.
2004: Adrian M Jubb; Thinh Q Pham; A M Hanby; Gretchen D Frantz; Franklin Peale; Thomas D Wu; H W Koeppen; Kenneth J Hillan
Expression of vascular endothelial growth factor, hypoxia inducible factor 1alpha, and carbonic anhydrase IX in human tumours.
Journal of clinical pathology 2004;57(5):504-12.
2004: Leon H Parker; Maike Schmidt; Suk-Won Jin; Alane M Gray; Dimitris Beis; Thinh Pham; Gretchen D Frantz; Susan Palmieri; Kenneth J Hillan; Didier Y R Stainier; Frederic J de Sauvage; Weilan Ye
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation.
Nature 2004;428(6984):754-8.
2003: Guido Sauter; Ronald Simon; Kenneth J Hillan
Tissue microarrays in drug discovery.
Nature reviews. Drug discovery 2003;2(12):962-72.
2003: Fiona Oakley; Nathan Trim; Christothea M Constandinou; Weilan Ye; Alane M Gray; Gretchen D Frantz; Kenneth J Hillan; Timothy Kendall; R Christopher Benyon; Derek A Mann; John P Iredale
Hepatocytes express nerve growth factor during liver injury: evidence for paracrine regulation of hepatic stellate cell apoptosis.
The American journal of pathology 2003;163(5):1849-58.
2003: Adrian M Jubb; T H Landon; J Burwick; Thinh Q Pham; Gretchen D Frantz; B Cairns; Philip Quirke; Franklin Peale; Kenneth J Hillan
Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization.
The Journal of pathology 2003;200(5):577-88.
2003: Jennifer LeCouter; Rui Lin; Gretchen D Frantz; Zemin Zhang; Kenneth J Hillan; Napoleone Ferrara
Mouse endocrine gland-derived vascular endothelial growth factor: a distinct expression pattern from its human ortholog suggests different roles as a regulator of organ-specific angiogenesis.
Endocrinology 2003;144(6):2606-16.
2003: Jennifer LeCouter; Rui Lin; Max Tejada; Gretchen D Frantz; Franklin Peale; Kenneth J Hillan; Napoleone Ferrara
The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2685-90.
2003: Jennifer LeCouter; Dirk R Moritz; Bing Li; Gail Lewis Phillips; Xiao Huan Liang; Hans-Peter Gerber; Kenneth J Hillan; Napoleone Ferrara
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.
Science (New York, N.Y.) 2003;299(5608):890-3.
2002: Katrina Nicholes; Susan Guillet; Elizabeth Tomlinson; Kenneth J Hillan; Barbara Wright; Gretchen D Frantz; Thinh A Pham; Lisa Dillard-Telm; Siao Ping Tsai; Jean-Philippe Stephan; Jeremy Stinson; Timothy Stewart; Dorothy M French
A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice.
The American journal of pathology 2002;160(6):2295-307.
2002: Sarajane Ross; Susan D Spencer; Ilona Holcomb; Christine Tan; Jo-Anne Hongo; Brigitte Devaux; Linda Rangell; Gilbert A Keller; Peter Schow; Rita M Steeves; Robert J Lutz; Gretchen D Frantz; Kenneth J Hillan; Franklin Peale; Patti Tobin; David A Eberhard; Mark A Rubin; Laurence A Lasky; Hartmut Koeppen
Prostate stem cell antigen as therapy target: tissue expression and in vivo efficacy of an immunoconjugate.
Cancer research 2002;62(9):2546-53.
2001: Liping Cai; Jian Ping Yin; Melissa A Starovasnik; Deborah A Hogue; Kenneth J Hillan; J S Mort; Ellen H Filvaroff
Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo.
Cytokine 2001;16(1):10-21.
2001: Gretchen D Frantz; Thinh Q Pham; Franklin Peale; Kenneth J Hillan
Detection of novel gene expression in paraffin-embedded tissues by isotopic in situ hybridization in tissue microarrays.
The Journal of pathology 2001;195(1):87-96.
2001: F Lewis; Nicola Joanne Maughan; V Smith; Kenneth J Hillan; Philip Quirke
Unlocking the archive--gene expression in paraffin-embedded tissue.
The Journal of pathology 2001;195(1):66-71.
2001: Kenneth J Hillan; Philip Quirke
Preface to genomic pathology--a new frontier.
The Journal of pathology 2001;195(1):1-2.
2001: Jennifer LeCouter; Joe Kowalski; J Foster; Philip E Hass; Zemin Zhang; Lisa Dillard-Telm; Gretchen D Frantz; Linda Rangell; L DeGuzman; Gilbert A Keller; Franklin Peale; Austin Gurney; Kenneth J Hillan; Napoleone Ferrara
Identification of an angiogenic mitogen selective for endocrine gland endothelium.
Nature 2001;412(6850):877-84.
2001: David Lawrence; Zahra Shahrokh; Scot A Marsters; K Achilles; D Shih; B Mounho; Kenneth J Hillan; Klara Totpal; Laura E DeForge; Peter Schow; J Hooley; Steven Sherwood; R Pai; S Leung; L Khan; B Gliniak; J Bussiere; C A Smith; S S Strom; S Kelley; Judith A Fox; D Thomas; Avi Ashkenazi
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions.
Nature medicine 2001;7(4):383-5.
2001: Hartmut Koeppen; B D Wright; A D Burt; Philip Quirke; Anne McNicol; Noel Dybdal; M X Sliwkowski; Kenneth J Hillan
Overexpression of HER2/neu in solid tumours: an immunohistochemical survey.
Histopathology 2001;38(2):96-104.
2000: PD Sehl; J T Tai; Kenneth J Hillan; L A Brown; A Goddard; R Yang; H Jin; DG Lowe
Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury.
Circulation 2000;101(16):1990-9.
1999: Kenneth J Hillan; KE Hagler; R N MacSween; AM Ryan; ME Renz; Henry H Chiu; R K Ferrier; G L Bird; A P Dhillon; L D Ferrell; Sherman Fong
Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease.
Liver 1999;19(6):509-18.
1999: Ming-Hong Xie; I Holcomb; B Deuel; Patrick Dowd; A Huang; A Vagts; Jessica Foster; J Liang; J Brush; Q Gu; Kenneth J Hillan; A Goddard; Austin Gurney
FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4.
Cytokine 1999;11(10):729-35.
1999: Richard A Shimkets; DG Lowe; J T Tai; PD Sehl; H Jin; R Yang; Paul Predki; B E Rothberg; M T Murtha; M E Roth; SG Shenoy; A Windemuth; JW Simpson; Jan Fredrik Simons; M P Daley; S A Gold; McKenna Michael; Kenneth J Hillan; G T Went; Jonathan M Rothberg
Gene expression analysis by transcript profiling coupled to a gene database query.
Nature biotechnology 1999;17(8):798-803.
1999: Hans-Peter Gerber; Kenneth J Hillan; AM Ryan; Joe Kowalski; Gilbert A Keller; Linda Rangell; B D Wright; Freddy Radtke; Michel Aguet; Napoleone Ferrara
VEGF is required for growth and survival in neonatal mice.
Development (Cambridge, England) 1999;126(6):1149-59.
1998: Robert M Pitti; Scot A Marsters; David A Lawrence; M Roy; Frank Kischkel; Patrick Dowd; A Huang; C J Donahue; S W Sherwood; DT Baldwin; Paul J Godowski; William I Wood; Austin Gurney; Kenneth J Hillan; R L Cohen; Audrey D Goddard; D Botstein; Avi Ashkenazi
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer.
Nature 1998;396(6712):699-703.
1998: Diane Pennica; T A Swanson; J W Welsh; M A Roy; David A Lawrence; Asuka Morimoto; J Brush; Lisa Anne Taneyhill; B Deuel; M Lew; C Watanabe; R L Cohen; M F Melhem; G G Finley; Philip Quirke; Audrey D Goddard; Kenneth J Hillan; Austin Gurney; D Botstein; Arnold J Levine
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14717-22.
1998: Napoleone Ferrara; H Chen; T Davis-Smyth; Hans-Peter Gerber; T N Nguyen; DH Peers; V Chisholm; Kenneth J Hillan; Ralph Schwall
Vascular endothelial growth factor is essential for corpus luteum angiogenesis.
Nature medicine 1998;4(3):336-40.
1997: D Zhang; M X Sliwkowski; M Mark; Gretchen D Frantz; Robert W Akita; Y Sun; Kenneth J Hillan; Craig W Crowley; J Brush; Paul J Godowski
Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9562-7.
1996: A W Burr; Kenneth J Hillan; K E McLaughlin; Rhona Ferrier; C Chapman; J Mathew; Alastair D Burt
Hepatocyte growth factor levels in liver and serum increase during chemical hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 1996;24(5):1282-7.
1996: J L Viney; S Jones; Henry H Chiu; B Lagrimas; ME Renz; Leonard G Presta; D Jackson; Kenneth J Hillan; S Lew; Sherman Fong
Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2488-97.
1996: E A McCruden; Kenneth J Hillan; I C McKay; M T Cassidy; J C Clark
Hepatitis virus infection and liver disease in injecting drug users who died suddenly.
Journal of clinical pathology 1996;49(7):552-5.
1996: R H Schwall; L Y Chang; Paul J Godowski; D W Kahn; Kenneth J Hillan; K D Bauer; Thomas F Zioncheck
Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.
The Journal of cell biology 1996;133(3):709-18.
1996: Napoleone Ferrara; K Carver-Moore; H Chen; M Dowd; L Lu; K Sue O'Shea; Lyn Powell-Braxton; Kenneth J Hillan; M W Moore
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene.
Nature 1996;380(6573):439-42.
1996: Kenneth J Hillan; M C Logan; R K Ferrier; G L Bird; G L Bennett; I C McKay; R N MacSween
Hepatocyte proliferation and serum hepatocyte growth factor levels in patients with alcoholic hepatitis.
Journal of hepatology 1996;24(4):385-90.
1996: J Nagy; G W Curry; Kenneth J Hillan; I C McKay; EA Mallon; AD Purushotham; W David George
Hepatocyte growth factor/scatter factor expression and c-met in primary breast cancer.
Surgical oncology 1996;5(1):15-21.
1995: S E Doughty; R K Ferrier; Kenneth J Hillan; D G Jackson
The effects of ZENECA ZD8731, an angiotensin II antagonist, on renin expression by juxtaglomerular cells in the rat: comparison of protein and mRNA expression as detected by immunohistochemistry and in situ hybridization.
Toxicologic pathology 1995;23(3):256-61.
1995: G L Bird; C J Tibbs; D Orton; Kenneth J Hillan; R N MacSween; R Williams; Peter R Mills
Does hepatitis C contribute to liver injury in alcohol abusers in the west of Scotland?
European journal of gastroenterology & hepatology 1995;7(2):161-3.
1995: G L Bird; E Spence; Kenneth J Hillan; R N MacSween; D Frame; P Yap; B Dow; F McOmish; Peter R Mills
Genotypic variation, clinical and histological characteristics of chronic hepatitis C detected at blood donor screening.
Journal of viral hepatitis 1995;2(5):261-5.
1989: Kenneth J Hillan; Alastair D Burt; W David George; R N MacSween; M R Griffiths; J A Bradley
Intrasplenic hepatocyte transplantation in rats with experimental liver injury: morphological and morphometric studies.
The Journal of pathology 1989;159(1):67-73.