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Arthur Hilliker

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Sepehr Bahadorani; Spencer Mukai; Dieter Egli; Arthur J Hilliker
Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity.
Sepehr Bahadorani; Peyman Bahadorani; Edyta Marcon; David W Walker; Arthur J Hilliker
A Drosophila model of Menkes disease reveals a role for DmATP7 in copper absorption and neurodevelopment.
Shawna Wicks; Nathan Bain; Atanu Duttaroy; Arthur J Hilliker; John P Phillips
Hypoxia rescues early mortality conferred by superoxide dismutase deficiency.

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All Publications

2010: Sepehr Bahadorani; Spencer Mukai; Dieter Egli; Arthur J Hilliker
Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity.
Neurobiology of aging 2010;31(7):1215-26.
2010: Sepehr Bahadorani; Peyman Bahadorani; Edyta Marcon; David W Walker; Arthur J Hilliker
A Drosophila model of Menkes disease reveals a role for DmATP7 in copper absorption and neurodevelopment.
Disease models & mechanisms 2010;3(1-2):84-91.
2009: Shawna Wicks; Nathan Bain; Atanu Duttaroy; Arthur J Hilliker; John P Phillips
Hypoxia rescues early mortality conferred by superoxide dismutase deficiency.
Free radical biology & medicine 2009;46(2):176-81.
2008: Benjamin R Strub; Tony L Parkes; Spencer T Mukai; Sepehr Bahadorani; Alistair B Coulthard; Nichole Hall; John P Phillips; Arthur J Hilliker
Mutations of the withered (whd) gene in Drosophila melanogaster confer hypersensitivity to oxidative stress and are lesions of the carnitine palmitoyltransferase I (CPT I) gene.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2008;51(6):409-20.
2008: Sepehr Bahadorani; Arthur J Hilliker
Antioxidants cannot suppress the lethal phenotype of a Drosophila melanogaster model of Huntington's disease.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2008;51(5):392-5.
2008: Peter R Anderson; Kim Kirby; William C Orr; Arthur J Hilliker; John P Phillips
Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):611-6.
2008: Sepehr Bahadorani; Peyman Bahadorani; John P Phillips; Arthur J Hilliker
The effects of vitamin supplementation on Drosophila life span under normoxia and under oxidative stress.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(1):35-42.
2007: J D J Labonne; Arthur J Hilliker; Joel S Shore
Meiotic recombination in Turnera (Turneraceae): extreme sexual difference in rates, but no evidence for recombination suppression associated with the distyly (S) locus.
Heredity 2007;98(6):411-8.
2007: Jerry Machado; Parween Abdulla; W J Brad Hanna; Arthur J Hilliker; Imogen R Coe
Genomic analysis of nucleoside transporters in Diptera and functional characterization of DmENT2, a Drosophila equilibrative nucleoside transporter.
Physiological genomics 2007;28(3):337-47.
2005: Peter R Anderson; Kim Kirby; Arthur J Hilliker; John P Phillips
RNAi-mediated suppression of the mitochondrial iron chaperone, frataxin, in Drosophila.
Human molecular genetics 2005;14(22):3397-405.
2005: Alistair B Coulthard; Nadia Nolan; John B Bell; Arthur J Hilliker
Transvection at the vestigial locus of Drosophila melanogaster.
Genetics 2005;170(4):1711-21.
2005: F Tamari; D Khosravi; Arthur J Hilliker; Joel S Shore
Inheritance of spontaneous mutant homostyles in Turnera subulata x krapovickasii and in autotetraploid T. scabra (Turneraceae).
Heredity 2005;94(2):207-16.
2004: R C Woodruff; John P Phillips; Arthur J Hilliker
Increased spontaneous DNA damage in Cu/Zn superoxide dismutase (SOD1) deficient Drosophila.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2004;47(6):1029-35.
2004: George J Bikopoulos; Rolando B Ceddia; Gary Sweeney; Arthur J Hilliker
Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells.
Cell proliferation 2004;37(4):307-16.
2003: Rolando B Ceddia; George J Bikopoulos; Arthur J Hilliker; Gary Sweeney
Insulin stimulates glucose metabolism via the pentose phosphate pathway in Drosophila Kc cells.
FEBS letters 2003;555(2):307-10.
2003: Fanis Missirlis; Jianguo Hu; Kim Kirby; Arthur J Hilliker; Tracey A Rouault; John P Phillips
Compartment-specific protection of iron-sulfur proteins by superoxide dismutase.
The Journal of biological chemistry 2003;278(48):47365-9.
2003: Alistair B Coulthard; Daniel F Eberl; Cecil B Sharp; Arthur J Hilliker
Genetic analysis of the second chromosome centromeric heterochromatin of Drosophila melanogaster.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2003;46(3):343-52.
2003: Fanis Missirlis; Stefan Rahlfs; Nikolaos Dimopoulos; Holger Bauer; Katja Becker; Arthur J Hilliker; John P Phillips; Herbert Jäckle
A putative glutathione peroxidase of Drosophila encodes a thioredoxin peroxidase that provides resistance against oxidative stress but fails to complement a lack of catalase activity.
Biological chemistry 2003;384(3):463-72.
2002: Kim Kirby; Jianguo Hu; Arthur J Hilliker; John P Phillips
RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16162-7.
2002: Narendra Sankar; Jerry Machado; Parween Abdulla; Arthur J Hilliker; Imogen R Coe
Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity.
Nucleic acids research 2002;30(20):4339-50.
2000: SA Shaver; C A Riedl; TL Parkes; Marla B Sokolowski; Arthur J Hilliker
Isolation of larval behavioral mutants in Drosophila melanogaster.
Journal of neurogenetics 2000;14(4):193-205.
2000: John P Phillips; TL Parkes; Arthur J Hilliker
Targeted neuronal gene expression and longevity in Drosophila.
Experimental gerontology 2000;35(9-10):1157-64.
2000: J W Wang; J M Humphreys; John P Phillips; Arthur J Hilliker; Chun-Fang Wu
A novel leg-shaking Drosophila mutant defective in a voltage-gated K(+)current and hypersensitive to reactive oxygen species.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(16):5958-64.
2000: P Yang; SA Shaver; Arthur J Hilliker; Marla B Sokolowski
Abnormal turning behavior in Drosophila larvae. Identification and molecular analysis of scribbler (sbb).
Genetics 2000;155(3):1161-74.
1999: TL Parkes; Arthur J Hilliker; John P Phillips
Motorneurons, reactive oxygen, and life span in Drosophila.
Neurobiology of aging 1999;20(5):531-5.
1999: A J Elia; TL Parkes; K Kirby; Peter St George-Hyslop; Gabrielle L Boulianne; J P Phillips; Arthur J Hilliker
Expression of human FALS SOD in motorneurons of Drosophila.
Free radical biology & medicine 1999;26(9-10):1332-8.
1998: TL Parkes; Kim Kirby; John P Phillips; Arthur J Hilliker
Transgenic analysis of the cSOD-null phenotypic syndrome in Drosophila.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1998;41(5):642-51.
1998: SA Shaver; C J Varnam; Arthur J Hilliker; Marla B Sokolowski
The foraging gene affects adult but not larval olfactory-related behavior in Drosophila melanogaster.
Behavioural brain research 1998;95(1):23-9.
1998: TL Parkes; A J Elia; Dale A Dickinson; Arthur J Hilliker; John P Phillips; Gabrielle L Boulianne
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.
Nature genetics 1998;19(2):171-4.
1997: A Duttaroy; TL Parkes; P Emtage; Kim Kirby; Gabrielle L Boulianne; X Wang; Arthur J Hilliker; John P Phillips
The manganese superoxide dismutase gene of Drosophila: structure, expression, and evidence for regulation by MAP kinase.
DNA and cell biology 1997;16(4):391-9.
1996: J M Humphreys; B Duyf; M L Joiner; John P Phillips; Arthur J Hilliker
Genetic analysis of oxygen defense mechanisms in Drosophila melanogaster and identification of a novel behavioural mutant with a Shaker phenotype.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1996;39(4):749-57.
1995: John P Phillips; J A Tainer; E D Getzoff; Gabrielle L Boulianne; Kim Kirby; Arthur J Hilliker
Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8574-8.
1994: Arthur J Hilliker; George Harauz; A G Reaume; M Gray; S H Clark; A Chovnick
Meiotic gene conversion tract length distribution within the rosy locus of Drosophila melanogaster.
Genetics 1994;137(4):1019-26.
1994: A Duttaroy; R Meidinger; Kim Kirby; S Carmichael; Arthur J Hilliker; J Phillips
A manganese superoxide dismutase-encoding cDNA from Drosophila melanogaster.
Gene 1994;143(2):223-5.
1994: I Reveillaud; J Phillips; B Duyf; Arthur J Hilliker; A Kongpachith; J E Fleming
Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.
Molecular and cellular biology 1994;14(2):1302-7.
1993: TL Parkes; Arthur J Hilliker; John P Phillips
Genetic and biochemical analysis of glutathione-S-transferase in the oxygen defense system of Drosophila melanogaster.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1993;36(6):1007-14.
1993: D F Eberl; B J Duyf; Arthur J Hilliker
The role of heterochromatin in the expression of a heterochromatic gene, the rolled locus of Drosophila melanogaster.
Genetics 1993;134(1):277-92.
1993: J M Humphreys; Arthur J Hilliker; John P Phillips
Paraquat selection identifies X-linked oxygen defense genes in Drosophila melanogaster.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1993;36(1):162-5.
1992: Arthur J Hilliker; B Duyf; D Evans; John P Phillips
Urate-null rosy mutants of Drosophila melanogaster are hypersensitive to oxygen stress.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4343-7.
1992: D F Eberl; L A Perkins; M Engelstein; Arthur J Hilliker; N Perrimon
Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster.
Genetics 1992;130(3):569-83.
1991: Arthur J Hilliker; S H Clark; A Chovnick
The effect of DNA sequence polymorphisms on intragenic recombination in the rosy locus of Drosophila melanogaster.
Genetics 1991;129(3):779-81.
1991: B E Staveley; Arthur J Hilliker; John P Phillips
Genetic organization of the cSOD microregion of Drosophila melanogaster.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1991;34(2):279-82.
1990: B E Staveley; John P Phillips; Arthur J Hilliker
Phenotypic consequences of copper-zinc superoxide dismutase overexpression in Drosophila melanogaster.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1990;33(6):867-72.
1990: C B Sharp; Arthur J Hilliker
Segregation ratios within Segregation Distorter lines of Drosophila melanogaster conform to a beta-binomial distribution.
Genetical research 1990;55(3):165-70.
1990: John P Phillips; Arthur J Hilliker
Genetic analysis of oxygen defense mechanisms in Drosophila melanogaster.
Advances in genetics 1990;28():43-71.
1989: Arthur J Hilliker; R Appels
The arrangement of interphase chromosomes: structural and functional aspects.
Experimental cell research 1989;185(2):267-318.
1989: D F Eberl; Arthur J Hilliker; C B Sharp; S N Trusis-Coulter
Further observations on the nature of radiation-induced chromosomal interchanges recovered from Drosophila sperm.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;32(5):847-55.
1989: C B Sharp; Arthur J Hilliker
Linkage and segregation distortion in Drosophila melanogaster.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;32(5):840-6.
1989: John P Phillips; S D Campbell; D Michaud; M Charbonneau; Arthur J Hilliker
Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2761-5.
1988: S H Clark; Arthur J Hilliker; A Chovnick
Recombination can initiate and terminate at a large number of sites within the rosy locus of Drosophila melanogaster.
Genetics 1988;118(2):261-6.
1988: D F Eberl; Arthur J Hilliker
Characterization of X-linked recessive lethal mutations affecting embryonic morphogenesis in Drosophila melanogaster.
Genetics 1988;118(1):109-20.
1987: Arthur J Hilliker; S N Trusis-Coulter
Analysis of the functional significance of linkage group conservation in Drosophila.
Genetics 1987;117(2):233-44.
1986: S H Clark; Arthur J Hilliker; A Chovnick
Genetic analysis of the right (3') end of the rosy locus in Drosophila melanogaster.
Genetical research 1986;47(2):109-16.
1986: S D Campbell; Arthur J Hilliker; John P Phillips
Cytogenetic analysis of the cSOD microregion in Drosophila melanogaster.
Genetics 1986;112(2):205-15.
1984: S H Clark; S Daniels; C A Rushlow; Arthur J Hilliker; A Chovnick
Tissue-specific and pretranslational character of variants of the rosy locus control element in Drosophila melanogaster.
Genetics 1984;108(4):953-68.
1982: Arthur J Hilliker; D G Holm; R Appels
The relationship between heterochromatic homology and meiotic segregation of compound second autosomes during spermatogenesis in Drosophila melanogaster.
Genetical research 1982;39(2):157-68.
1982: R Appels; Arthur J Hilliker
The cytogenetic boundaries of the rDNA region within heterochromatin in the X chromosome of Drosophila melanogaster and their relation to male meiotic pairing sites.
Genetical research 1982;39(2):149-56.
1982: Arthur J Hilliker; R Appels
Pleiotropic effects associated with the deletion of heterochromatin surrounding rDNA on the X chromosome of Drosophila.
Chromosoma 1982;86(4):469-90.
1981: Arthur J Hilliker; A Chovnick
Further observations on intragenic recombination in Drosophila melanogaster.
Genetical research 1981;38(3):281-96.
1980: Arthur J Hilliker; R Appels; A Schalet
The genetic analysis of D. melanogaster heterochromatin.
Cell 1980;21(3):607-19.
1980: Arthur J Hilliker; S H Clark; A Chovnick; W M Gelbart
Cytogenetic analysis of the chromosomal region immediately adjacent to the rosy locus in Drosophila melanogaster.
Genetics 1980;95(1):95-110.
1980: A Chovnick; M McCarron; S H Clark; Arthur J Hilliker; C A Rushlow
Structural and functional organization of a gene in Drosophila melanogaster.
Basic life sciences 1980;16():3-23.