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Ole Hindsgaul

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bent petersen; Ole Olsen; Sophie R Beeren; Ole Hindsgaul; Sebastian Meier
Monitoring pathways of β-glucan degradation by enzyme mixtures in situ.
Richard B Keithley; Monica M Palcic; Alison S Rosenthal; Hidenori Tanaka; Yayoi Yoshimura; David C Essaka; Ole Hindsgaul; Norman J Dovichi
Capillary electrophoresis with three-color fluorescence detection for the analysis of glycosphingolipid metabolism.
Hidenori Tanaka; Yayoi Yoshimura; Jose A Cuesta-Seijo; Malene R Jørgensen; Ole Hindsgaul
A simple synthesis of sugar nucleoside diphosphates by chemical coupling in water.

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2013: bent petersen; Ole Olsen; Sophie R Beeren; Ole Hindsgaul; Sebastian Meier
Monitoring pathways of β-glucan degradation by enzyme mixtures in situ.
Carbohydrate research 2013;368():47-51.
2013: Richard B Keithley; Monica M Palcic; Alison S Rosenthal; Hidenori Tanaka; Yayoi Yoshimura; David C Essaka; Ole Hindsgaul; Norman J Dovichi
Capillary electrophoresis with three-color fluorescence detection for the analysis of glycosphingolipid metabolism.
The Analyst 2013;138(1):164-70.
2012: Hidenori Tanaka; Yayoi Yoshimura; Jose A Cuesta-Seijo; Malene R Jørgensen; Ole Hindsgaul
A simple synthesis of sugar nucleoside diphosphates by chemical coupling in water.
Angewandte Chemie (International ed. in English) 2012;51(46):11531-4.
2012: Dietlind Adlercreutz; Eric P Bennett; Norman J Dovichi; Ole Hindsgaul; Karin Mannerstedt; Warren W Wakarchuk; Yayoi Yoshimura; Monica M Palcic
Thiogalactopyranosides are resistant to hydrolysis by α-galactosidases.
Chembiochem : a European journal of chemical biology 2012;13(11):1673-9.
2012: David C Essaka; Ole Hindsgaul; Richard B Keithley; Monica M Palcic; Jillian Prendergast; Ronald Schnaar; Norman J Dovichi
Single cell ganglioside catabolism in primary cerebellar neurons and glia.
Neurochemical research 2012;37(6):1308-14.
2012: Sine A Johannesen; Byung Y Yang; Sophie R Beeren; Dennis Blank; Rudolf Geyer; Ole Hindsgaul
Glycan analysis via derivatization with a fluorogenic pyrylium dye.
Carbohydrate research 2012;352():94-100.
2012: David C Essaka; Ole Hindsgaul; Richard B Keithley; Monica M Palcic; Jillian Prendergast; Ronald Schnaar; Norman J Dovichi
Metabolic cytometry: capillary electrophoresis with two-color fluorescence detection for the simultaneous study of two glycosphingolipid metabolic pathways in single primary neurons.
Analytical chemistry 2012;84(6):2799-804.
2012: Scott A Sarver; Hidenori Tanaka; Yayoi Yoshimura; David C Essaka; Ole Hindsgaul; Richard B Keithley; Monica M Palcic; Norman J Dovichi
Preparation and electrophoretic separation of Bodipy-Fl-labeled glycosphingolipids.
Journal of chromatography. A 2012;1229():268-73.
2012: Yayoi Yoshimura; Aaron S Nudelman; Hans Wandall; Eric P Bennett; Henrik Clausen; Ole Hindsgaul; Steven B Levery; Shin-ichiro Nishimura
Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates.
Glycobiology 2012;22(3):429-38.
2011: Oluwatosin O Dada; David C Essaka; Ole Hindsgaul; Monica M Palcic; Jillian Prendergast; Ronald Schnaar; Norman J Dovichi
Nine orders of magnitude dynamic range: picomolar to millimolar concentration measurement in capillary electrophoresis with laser induced fluorescence detection employing cascaded avalanche photodiode photon counters.
Analytical chemistry 2011;83(7):2748-53.
2011: Jennifer A Harrison; K P Ravindranathan Kartha; Eric J L Fournier; Todd L Lowary; Carles Malet; Ulf J Nilsson; Ole Hindsgaul; Sergio Schenkman; James H Naismith; Robert A Field
Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries.
Organic & biomolecular chemistry 2011;9(5):1653-60.
2010: David C Essaka; John White; Pradip Rathod; Colin D Whitmore; Ole Hindsgaul; Monica M Palcic; Norman J Dovichi
Monitoring the uptake of glycosphingolipids in Plasmodium falciparum-infected erythrocytes using both fluorescence microscopy and capillary electrophoresis with laser-induced fluorescence detection.
Analytical chemistry 2010;82(23):9955-8.
2010: Karin Mannerstedt; Anita M Jansson; Jody Weadge; Ole Hindsgaul
Small-molecule sensing: a direct enzyme-linked immunosorbent assay for the monosaccharide Kdo.
Angewandte Chemie (International ed. in English) 2010;49(44):8173-6.
2010: Mikkel B Thygesen; Henrik Munch; Jørgen Sauer; Emiliano Cló; Malene R Jørgensen; Ole Hindsgaul; Knud J Jensen
Nucleophilic catalysis of carbohydrate oxime formation by anilines.
The Journal of organic chemistry 2010;75(5):1752-5.
2009: Junya Mitoma; Tatsuo Miyazaki; Mark Sutton-Smith; Misa Suzuki; Hideo Saito; Jiunn-Chern Yeh; Takehiro Kawano; Ole Hindsgaul; Peter H Seeberger; Maria Panico; Stuart M Haslam; Howard R Morris; Richard D Cummings; Anne Dell; Minoru Fukuda
The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells.
Glycoconjugate journal 2009;26(5):511-23.
2008: Linda J Olson; Ole Hindsgaul; Nancy M Dahms; Jung-Ja P Kim
Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor.
The Journal of biological chemistry 2008;283(15):10124-34.
2008: Karin Mannerstedt; Ole Hindsgaul
Synthesis and photolytic activation of 6''-O-2-nitrobenzyl uridine-5'-diphosphogalactose: a 'caged' UDP-Gal derivative.
Carbohydrate research 2008;343(5):875-81.
2008: Tatsuo Miyazaki; Kiyohiko Angata; Peter H Seeberger; Ole Hindsgaul; Minoru Fukuda
CMP substitutions preferentially inhibit polysialic acid synthesis.
Glycobiology 2008;18(2):187-94.
2008: Inka Brockhausen; E Andreas Larsson; Ole Hindsgaul
A very simple synthesis of GlcNAc-alpha-pyrophosphoryl-decanol: a substrate for the assay of a bacterial galactosyltransferase.
Bioorganic & medicinal chemistry letters 2008;18(2):804-7.
2008: Daniella Cohen; Jane A Dickerson; Colin D Whitmore; Emily H Turner; Monica Palcic; Ole Hindsgaul; Norman J Dovichi
Chemical cytometry: fluorescence-based single-cell analysis.
Annual review of analytical chemistry (Palo Alto, Calif.) 2008;1():165-90.
2007: Colin D Whitmore; Ulf Olsson; E Andreas Larsson; Ole Hindsgaul; Monica Palcic; Norman J Dovichi
Yoctomole analysis of ganglioside metabolism in PC12 cellular homogenates.
Electrophoresis 2007;28(17):3100-4.
2007: Colin D Whitmore; Ole Hindsgaul; Monica Palcic; Ronald Schnaar; Norman J Dovichi
Metabolic cytometry. Glycosphingolipid metabolism in single cells.
Analytical chemistry 2007;79(14):5139-42.
2007: E Andreas Larsson; Ulf Olsson; Colin D Whitmore; Rita Martins; Guido Tettamanti; Ronald Schnaar; Norman J Dovichi; Monica Palcic; Ole Hindsgaul
Synthesis of reference standards to enable single cell metabolomic studies of tetramethylrhodamine-labeled ganglioside GM1.
Carbohydrate research 2007;342(3-4):482-9.
2007: Ella S M Ng; Nora W C Chan; Darren F Lewis; Ole Hindsgaul; David C Schriemer
Frontal affinity chromatography-mass spectrometry.
Nature protocols 2007;2(8):1907-17.
2007: Mads D Sørensen; Rita Martins; Ole Hindsgaul
Assessing the terminal glycosylation of a glycoprotein by the naked eye.
Angewandte Chemie (International ed. in English) 2007;46(14):2403-7.
2006: Taku Nakahara; Ole Hindsgaul; Monica Palcic; Shin-Ichiro Nishimura
Computational design and experimental evaluation of glycosyltransferase mutants: engineering of a blood type B galactosyltransferase with enhanced glucosyltransferase activity.
Protein engineering, design & selection : PEDS 2006;19(12):571-8.
2006: Sébastien Fort; Hyo-Sun Kim; Ole Hindsgaul
Screening for galectin-3 inhibitors from synthetic lacto-N-biose libraries using microscale affinity chromatography coupled to mass spectrometry.
The Journal of organic chemistry 2006;71(19):7146-54.
2006: Frank Schweizer; Ole Hindsgaul
Synthesis of a galacto-configured C-ketoside-based gamma-sugar-amino acid and its use in peptide coupling reactions.
Carbohydrate research 2006;341(10):1730-6.
2006: Anders Lohse; Rita Martins; Malene Ryborg Jørgensen; Ole Hindsgaul
Solid-phase oligosaccharide tagging (SPOT): Validation on glycolipid-derived structures.
Angewandte Chemie (International ed. in English) 2006;45(25):4167-72.
2005: Meenakshi Dowlut; Dennis G Hall; Ole Hindsgaul
Investigation of nonspecific effects of different dyes in the screening of labeled carbohydrates against immobilized proteins.
The Journal of organic chemistry 2005;70(24):9809-13.
2005: Ella S M Ng; Feng Yang; Akihiko Kameyama; Monica Palcic; Ole Hindsgaul; David C Schriemer
High-throughput screening for enzyme inhibitors using frontal affinity chromatography with liquid chromatography and mass spectrometry.
Analytical chemistry 2005;77(19):6125-33.
2005: Brian E Coggins; Amanda McClerren; Ling Jiang; Xuechen Li; Johannes Rudolph; Ole Hindsgaul; Christian R H Raetz; Pei Zhou
Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design.
Biochemistry 2005;44(4):1114-26.
2004: Shiro Nozawa; Daisuke Aoki; Katsumi Tsukazaki; Nobuyuki Susumu; Motoko Sakayori; Nao Suzuki; Atsushi Suzuki; Rie Wakita; Makio Mukai; Yuko Egami; Kyoko Kojima-Aikawa; Isao Ishida; Frederic Belot; Ole Hindsgaul; Minoru Fukuda; Michiko N Fukuda
HMMC-1: a humanized monoclonal antibody with therapeutic potential against Müllerian duct-related carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):7071-8.
2004: Brian E Coggins; Xuechen Li; Ole Hindsgaul; Christian R H Raetz; Pei Zhou
Assignment of the 1H, 13C and 15N resonances of the LpxC deacetylase from Aquifex aeolicus in complex with the substrate-analog inhibitor TU-514.
Journal of biomolecular NMR 2004;28(2):201-2.
2003: Brian E Coggins; Xuechen Li; Amanda McClerren; Ole Hindsgaul; Christian R H Raetz; Pei Zhou
Structure of the LpxC deacetylase with a bound substrate-analog inhibitor.
Nature structural biology 2003;10(8):645-51.
2003: Xuechen Li; Taketo Uchiyama; Christian R H Raetz; Ole Hindsgaul
Synthesis of a carbohydrate-derived hydroxamic acid inhibitor of the bacterial enzyme (LpxC) involved in lipid A biosynthesis.
Organic letters 2003;5(4):539-41.
2003: Monica Palcic; Boyan Zhang; Xiangping Qian; Brian Rempel; Ole Hindsgaul
Evaluating carbohydrate-protein binding interactions using frontal affinity chromatography coupled to mass spectrometry.
Methods in enzymology 2003;362():369-76.
2002: Linfeng Fan; Ole Hindsgaul
Synthesis of novel cyclic oligosaccharides: beta-1,6-thio-linked cycloglucopyranosides.
Organic letters 2002;4(25):4503-6.
2002: David Rabuka; Ole Hindsgaul
Synthesis and NMR characterization of the six regioisomeric monophosphates of octyl beta-D-galactopyranosyl-(1 --> 4)-2-acetamido-2-deoxy-beta-D-glucopyranoside.
Carbohydrate research 2002;337(21-23):2127-51.
2002: Tomoya O Akama; Anup K Misra; Ole Hindsgaul; Michiko N Fukuda
Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate.
The Journal of biological chemistry 2002;277(45):42505-13.
2002: Joseph C McAuliffe; David Rabuka; Ole Hindsgaul
Synthesis of O-glycolyl-linked neuraminic acids through a spirocyclic intermediate.
Organic letters 2002;4(18):3067-9.
2002: Nora W C Chan; Darren F Lewis; S Hewko; Ole Hindsgaul; David C Schriemer
Frontal affinity chromatography for the screening of mixtures.
Combinatorial chemistry & high throughput screening 2002;5(5):395-406.
2002: Anders Lohse; Frank Schweizer; Ole Hindsgaul
Synthesis of a 56 component library of sugar beta-peptides.
Combinatorial chemistry & high throughput screening 2002;5(5):389-94.
2002: Edgar Ong; Misa Suzuki; Frederic Belot; Jiunn-Chern Yeh; Isabelle Franceschini; Kiyohiko Angata; Ole Hindsgaul; Minoru Fukuda
Biosynthesis of HNK-1 glycans on O-linked oligosaccharides attached to the neural cell adhesion molecule (NCAM): the requirement for core 2 beta 1,6-N-acetylglucosaminyltransferase and the muscle-specific domain in NCAM.
The Journal of biological chemistry 2002;277(20):18182-90.
2002: Brian P Rempel; Harry C Winter; Irwin J Goldstein; Ole Hindsgaul
Characterization of the recognition of blood group B trisaccharide derivatives by the lectin from Marasmius oreades using frontal affinity chromatography-mass spectrometry.
Glycoconjugate journal 2002;19(3):175-80.
2001: B Zhang; Monica Palcic; David C Schriemer; Gerardo Alvarez-Manilla; James Michael Pierce; Ole Hindsgaul
Frontal affinity chromatography coupled to mass spectrometry for screening mixtures of enzyme inhibitors.
Analytical biochemistry 2001;299(2):173-82.
2001: Anup K Misra; Michiko N Fukuda; Ole Hindsgaul
Efficient synthesis of lactosaminylated core-2 O-glycans.
Bioorganic & medicinal chemistry letters 2001;11(20):2667-9.
2001: Monica Palcic; Nina O L Seto; Ole Hindsgaul
Natural and recombinant A and B gene encoded glycosyltransferases.
Transfusion medicine (Oxford, England) 2001;11(4):315-23.
2001: Jonathon W Homeister; A D Thall; Bronislawa Petryniak; P Malý; Clare E Rogers; Peter L Smith; Reagan J Kelly; K M Gersten; S W Askari; G Cheng; GM Smithson; Rory M Marks; A K Misra; Ole Hindsgaul; Ulrich H von Andrian; John B Lowe
The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.
Immunity 2001;15(1):115-26.
2001: Jiunn-Chern Yeh; Nobuyoshi Hiraoka; Bronislawa Petryniak; Jun Nakayama; Lesley G Ellies; David Rabuka; Ole Hindsgaul; Jamey D Marth; John B Lowe; Michiko N Fukuda
Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase.
Cell 2001;105(7):957-69.
2001: Atsushi Suzuki; Nobuyoshi Hiraoka; Misa Suzuki; Kiyohiko Angata; Anup K Misra; J McAuliffe; Ole Hindsgaul; Michiko N Fukuda
Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans.
The Journal of biological chemistry 2001;276(26):24388-95.
2001: Nobuyoshi Hiraoka; A Misra; Frederic Belot; Ole Hindsgaul; Michiko N Fukuda
Molecular cloning and expression of two distinct human N-acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1-->4GlcNAc beta 1-->R in both N- and O-glycans.
Glycobiology 2001;11(6):495-504.
2001: Tomoya O Akama; Jun Nakayama; Kohji Nishida; Nobuyoshi Hiraoka; Misa Suzuki; J McAuliffe; Ole Hindsgaul; Michiko N Fukuda; M N Fukuda
Human corneal GlcNac 6-O-sulfotransferase and mouse intestinal GlcNac 6-O-sulfotransferase both produce keratan sulfate.
The Journal of biological chemistry 2001;276(19):16271-8.
2001: B Zhang; Monica Palcic; H Mo; Irwin J Goldstein; Ole Hindsgaul
Rapid determination of the binding affinity and specificity of the mushroom Polyporus squamosus lectin using frontal affinity chromatography coupled to electrospray mass spectrometry.
Glycobiology 2001;11(2):141-7.
2001: Keykavous Parang; E J Fournier; Ole Hindsgaul
A solid phase reagent for the capture phosphorylation of carbohydrates and nucleosides.
Organic letters 2001;3(2):307-9.
2001: Anup K Misra; M Ujita; Michiko N Fukuda; Ole Hindsgaul
Synthesis and enzymatic evaluation of mucin type core 4 O-glycan.
Carbohydrate letters 2001;4(2):71-6.
2000: Anup K Misra; Y Ding; J B Lowe; Ole Hindsgaul
A concise synthesis of the 6-O- and 6'-O-sulfated analogues of the sialyl Lewis X tetrasaccharide.
Bioorganic & medicinal chemistry letters 2000;10(14):1505-9.
2000: Kiyohiko Angata; Misa Suzuki; J McAuliffe; Y Ding; Ole Hindsgaul; Michiko N Fukuda
Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III.
The Journal of biological chemistry 2000;275(24):18594-601.
2000: M Ujita; Anup K Misra; J McAuliffe; Ole Hindsgaul; Michiko N Fukuda
Poly-N-acetyllactosamine extension in N-glycans and core 2- and core 4-branched O-glycans is differentially controlled by i-extension enzyme and different members of the beta 1,4-galactosyltransferase gene family.
The Journal of biological chemistry 2000;275(21):15868-75.
2000: A Mukherjee; Monica Palcic; Ole Hindsgaul
Synthesis and enzymatic evaluation of modified acceptors of recombinant blood group A and B glycosyltransferases.
Carbohydrate research 2000;326(1):1-21.
2000: Jane E Jackman; Carol A Fierke; L Nathan Tumey; Michael C Pirrung; T Uchiyama; S H Tahir; Ole Hindsgaul; Christian R H Raetz
Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs.
The Journal of biological chemistry 2000;275(15):11002-9.
2000: Shigeru Tsuboi; O P Srivastava; Monica Palcic; Ole Hindsgaul; Michiko N Fukuda
Acquisition of P-selectin binding activity by en bloc transfer of sulfo Le(x) trisaccharide to the cell surface: comparison to a sialyl Le(x) tetrasaccharide transferred on the cell surface.
Archives of biochemistry and biophysics 2000;374(1):100-6.
1999: J C McAuliffe; M Ujita; Michiko N Fukuda; Ole Hindsgaul
Synthesis of selectively radiolabeled hexasaccharides for the determination of enzymatic regioselectivity.
Glycoconjugate journal 1999;16(12):767-72.
1999: UJ Nilsson; E J Fournier; E J Fryz; Ole Hindsgaul
Parallel solution synthesis of a "Carbohybrid" library designed to inhibit galactose-binding proteins.
Combinatorial chemistry & high throughput screening 1999;2(6):335-52.
1999: J C McAuliffe; Michiko N Fukuda; Ole Hindsgaul
Expedient synthesis of a series of N-acetyllactosamines.
Bioorganic & medicinal chemistry letters 1999;9(19):2855-8.
1999: Vivekanand P Kamath; Nina O L Seto; CA Compston; Ole Hindsgaul; Monica Palcic
Synthesis of the acceptor analog alphaFuc(1-->2)alphaGal-O(CH2)7 CH3: a probe for the kinetic mechanism of recombinant human blood group B glycosyltransferase.
Glycoconjugate journal 1999;16(10):599-606.
1999: Edgar Ong; Jiunn-Chern Yeh; Y Ding; Ole Hindsgaul; L C Pedersen; M Negishi; Michiko N Fukuda
Structure and function of HNK-1 sulfotransferase. Identification of donor and acceptor binding sites by site-directed mutagenesis.
The Journal of biological chemistry 1999;274(36):25608-12.
1999: C L Stults; Bruce A Macher; R Bhatti; O P Srivastava; Ole Hindsgaul
Characterization of the substrate specificity of alpha1,3galactosyltransferase utilizing modified N-acetyllactosamine disaccharides.
Glycobiology 1999;9(7):661-8.
1999: M Ujita; J McAuliffe; Ole Hindsgaul; K Sasaki; M N Fukuda; Michiko N Fukuda
Poly-N-acetyllactosamine synthesis in branched N-glycans is controlled by complemental branch specificity of I-extension enzyme and beta1,4-galactosyltransferase I.
The Journal of biological chemistry 1999;274(24):16717-26.
1999: Frank Schweizer; Ole Hindsgaul
Combinatorial synthesis of carbohydrates.
Current opinion in chemical biology 1999;3(3):291-8.
1999: M Ujita; J McAuliffe; Misa Suzuki; Ole Hindsgaul; Henrik Clausen; M N Fukuda; Michiko N Fukuda
Regulation of I-branched poly-N-acetyllactosamine synthesis. Concerted actions by I-extension enzyme, I-branching enzyme, and beta1,4-galactosyltransferase I.
The Journal of biological chemistry 1999;274(14):9296-304.
1999: X C Le; W Tan; Christine Scaman; Adam Szpacenko; Edgar A Arriaga; Y Zhang; Norman J Dovichi; Ole Hindsgaul; Monica Palcic
Single cell studies of enzymatic hydrolysis of a tetramethylrhodamine labeled triglucoside in yeast.
Glycobiology 1999;9(3):219-25.
1999: Albin Otter; R U Lemieux; R G Ball; A P Venot; Ole Hindsgaul; David R Bundle
Crystal state and solution conformation of the B blood group trisaccharide alpha-L-Fucp-(1-->2)-[alpha-D-Galp]-(1-->3)]-beta-D-Galp-OCH3.
European journal of biochemistry / FEBS 1999;259(1-2):295-303.
1998: M Ujita; J McAuliffe; Tilo Schwientek; Raquel Almeida; Ole Hindsgaul; Henrik Clausen; Michiko N Fukuda
Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans. The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase.
The Journal of biological chemistry 1998;273(52):34843-9.
1998: David C Schriemer; Ole Hindsgaul
Deconvolution approaches in screening compound mixtures.
Combinatorial chemistry & high throughput screening 1998;1(4):155-70.
1998: Y Ding; Ole Hindsgaul; Huiying Li; Monica Palcic
beta Gal(1-->S-4)beta GlcNac--OR: a galactosidase-stable substrate for alpha(1-->3)fucosyltransferase.
Bioorganic & medicinal chemistry letters 1998;8(22):3199-202.
1998: UJ Nilsson; E J Fournier; Ole Hindsgaul
Solid-phase extraction on C18 silica as a purification strategy in the solution synthesis of a 1-thio-beta-D-galactopyranoside library.
Bioorganic & medicinal chemistry 1998;6(9):1563-75.
1998: Frank Schweizer; H Jiao; Ole Hindsgaul; Wah Y Wong; Randall T Irvin
Interaction between the pili of Pseudomonas aeruginosa PAK and its carbohydrate receptor beta-D-GalNAc(1-->4)beta-D-Gal analogs.
Canadian journal of microbiology 1998;44(3):307-11.
1998: Edgar Ong; Jiunn-Chern Yeh; Y Ding; Ole Hindsgaul; Michiko N Fukuda
Expression cloning of a human sulfotransferase that directs the synthesis of the HNK-1 glycan on the neural cell adhesion molecule and glycolipids.
The Journal of biological chemistry 1998;273(9):5190-5.
1998: Z G Wang; Ole Hindsgaul
Combinatorial carbohydrate chemistry.
Advances in experimental medicine and biology 1998;435():219-36.
1997: K Stangier; Monica Palcic; David R Bundle; Ole Hindsgaul; Joachim Thiem
Fucosyltransferase-catalyzed formation of L-galactosylated Lewis structures.
Carbohydrate research 1997;305(3-4):511-5.
1997: Keiko Sujino; C Malet; Ole Hindsgaul; Monica Palcic
Acceptor hydroxyl group mapping for calf thymus alpha-(1-->3)-galactosyltransferase and enzymatic synthesis of alpha-D-Galp-(1-->3)-beta-D-Galp-(1-->4)-beta D-GlcpNAc analogs.
Carbohydrate research 1997;305(3-4):483-9.
1997: Y Dai; Randy M Whittal; C A Bridges; Y Isogai; Ole Hindsgaul; Liang Li
Matrix-assisted laser desorption ionization mass spectrometry for the analysis of monosulfated oligosaccharides.
Carbohydrate research 1997;304(1):1-9.
1997: P P Lu; Ole Hindsgaul; Huiying Li; Monica Palcic
Synthesis and evaluation of eight aminodeoxy trisaccharide inhibitors for N-acetylglucosaminyltransferase-V.
Carbohydrate research 1997;303(3):283-91.
1997: X Chris Le; Y Zhang; Norman J Dovichi; CA Compston; Monica Palcic; R J Beever; Ole Hindsgaul
Study of the enzymatic transformation of fluorescently labeled oligosaccharides in human epidermoid cells using capillary electrophoresis with laser-induced fluorescence detection.
Journal of chromatography. A 1997;781(1-2):515-22.
1997: UJ Nilsson; L D Heerze; Y C Liu; Glen D Armstrong; Monica Palcic; Ole Hindsgaul
Immobilization of reducing sugars as toxin binding agents.
Bioconjugate chemistry 1997;8(4):466-71.
1997: A Patricia Campbell; Wah Y Wong; M Houston; Frank Schweizer; PJ Cachia; Randall T Irvin; Ole Hindsgaul; Robert S Hodges; Brian D Sykes
Interaction of the receptor binding domains of Pseudomonas aeruginosa pili strains PAK, PAO, KB7 and P1 to a cross-reactive antibody and receptor analog: implications for synthetic vaccine design.
Journal of molecular biology 1997;267(2):382-402.
1996: Christine Scaman; Ole Hindsgaul; Monica Palcic; O P Srivastava
Synthesis of alpha-D-Glcp-(1-->2)-alpha-D-Glcp-(1-->3) -alpha-D-Glcp-O-(CH2)8 COOCH3 for use in the assay of alpha-glucosidase I activity.
Carbohydrate research 1996;296():203-13.
1996: P P Lu; Ole Hindsgaul; CA Compston; Monica Palcic
New synthetic trisaccharide inhibitors for N-acetylglucosaminyltransferase-V.
Bioorganic & medicinal chemistry 1996;4(11):2011-22.
1996: Shigeru Tsuboi; Y Isogai; N Hada; J K King; Ole Hindsgaul; Michiko N Fukuda
6'-Sulfo sialyl Lex but not 6-sulfo sialyl Lex expressed on the cell surface supports L-selectin-mediated adhesion.
The Journal of biological chemistry 1996;271(44):27213-6.
1996: M Du; Ole Hindsgaul
Recognition of beta-D-Gal p-(1-->3)-beta-D-Glc pNAc-OR acceptor analogues by the Lewis alpha-(1-->3/4)-fucosyltransferase from human milk.
Carbohydrate research 1996;286():87-105.
1996: Y Ding; J Labbe; Osamu Kanie; Ole Hindsgaul
Towards oligosaccharide libraries: a study of the random galactosylation of unprotected N-acetylglucosamine.
Bioorganic & medicinal chemistry 1996;4(5):683-92.
1996: V P Kamath; P Diedrich; Ole Hindsgaul
Use of diethyl squarate for the coupling of oligosaccharide amines to carrier proteins and characterization of the resulting neoglycoproteins by MALDI-TOF mass spectrometry.
Glycoconjugate journal 1996;13(2):315-9.
1996: V P Kamath; Ole Hindsgaul
Synthesis of alpha- and beta-L-Fuc p-(1-->2)-alpha-L-Fuc p-(1-->3)- beta-D-Gal pNAc glycosides identified as termini of Schistosoma mansoni oligosaccharides.
Carbohydrate research 1996;280(2):323-30.
1995: X Chris Le; C Scaman; Y Zhang; J Zhang; Norman J Dovichi; Ole Hindsgaul; Monica Palcic
Analysis by capillary electrophoresis-laser-induced fluorescence detection of oligosaccharides produced from enzyme reactions.
Journal of chromatography. A 1995;716(1-2):215-20.
1995: Nina O L Seto; Monica Palcic; Ole Hindsgaul; David R Bundle; Saran Narang
Expression of a recombinant human glycosyltransferase from a synthetic gene and its utilization for synthesis of the human blood group B trisaccharide.
European journal of biochemistry / FEBS 1995;234(1):323-8.
1995: R A Field; Albin Otter; W Fu; Ole Hindsgaul
Synthesis and 1H NMR characterization of the six isomeric mono-O-sulfates of 8-methoxycarbonyloct-1-yl O-beta-D-galactopyranosyl-(1-->4)-2-acetamido-2-deoxy-beta-D-glucopyran oside.
Carbohydrate research 1995;276(2):347-63.
1995: A C Helland; Ole Hindsgaul; Monica Palcic; C L Stults; Bruce A Macher
Methyl 3-amino-3-deoxy-beta-D-galactopyranosyl-(1-->4)-2-acetamido-2- deoxy-beta-D-glucopyranoside: an inhibitor of UDP-D-galactose: beta-D-galactopyranosyl-(1-->4)-2-acetamido-2-deoxy-D-glucose (1-->3)-alpha-D-galactopyranosyltransferase.
Carbohydrate research 1995;276(1):91-8.
1995: Albin Otter; Ole Hindsgaul; David R Bundle
Gradient-enhanced homonuclear 2D NMR techniques applied to oligosaccharides containing manno-hexoses provide improved correlations for protons coupled by small 3J.
Carbohydrate research 1995;275(2):381-9.
1995: Randy M Whittal; Monica Palcic; Ole Hindsgaul; Liang Li
Direct analysis of enzymatic reactions of oligosaccharides in human serum using matrix-assisted laser desorption ionization mass spectrometry.
Analytical chemistry 1995;67(19):3509-14.
1995: Seiichiro Ogawa; T Furuya; H Tsunoda; Ole Hindsgaul; K Stangier; Monica Palcic
Synthesis of beta-D-GlcpNAc-(1-->2)-5a-carba-alpha-D-Man p-(1-->6)-beta-D- Glcp-O(CH2)7CH3: a reactive acceptor analog for N-acetylglucosaminyltransferase-V.
Carbohydrate research 1995;271(2):197-205.
1995: Y Zhang; X Chris Le; Norman J Dovichi; CA Compston; Monica Palcic; P Diedrich; Ole Hindsgaul
Monitoring biosynthetic transformations of N-acetyllactosamine using fluorescently labeled oligosaccharides and capillary electrophoretic separation.
Analytical biochemistry 1995;227(2):368-76.
1995: Y Ding; Osamu Kanie; J Labbe; Monica Palcic; B Ernst; Ole Hindsgaul
Synthesis and biological activity of oligosaccharide libraries.
Advances in experimental medicine and biology 1995;376():261-9.
1994: Osamu Kanie; S C Crawley; Monica Palcic; Ole Hindsgaul
Key involvement of all three GlcNAc hydroxyl groups in the recognition of beta-D-GlcpNAc-(1-->2)-alpha-D-Manp-(1-->6)-beta-D-Glcp-OR by N-acetylglucosaminyltransferase-V.
Bioorganic & medicinal chemistry 1994;2(11):1231-41.
1994: S H Khan; CA Compston; Monica Palcic; Ole Hindsgaul
Synthesis of a di-O-methylated pentasaccharide for use in the assay of N-acetylglucosaminyltransferase III activity.
Carbohydrate research 1994;262(2):283-95.
1994: J Y Zhao; P Diedrich; Y Zhang; Ole Hindsgaul; Norman J Dovichi
Separation of aminated monosaccharides by capillary zone electrophoresis with laser-induced fluorescence detection.
Journal of chromatography. B, Biomedical applications 1994;657(2):307-13.
1994: C Hällgren; Ole Hindsgaul
Synthesis of octyl 2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranoside, its 6'-phosphate and the corresponding monomethyl phosphodiester: intermediate structures in the biosynthesis of N-linked oligosaccharides in Dictyostelium discoidium.
Carbohydrate research 1994;260(1):63-71.
1994: L Yu; KK Lee; H B Sheth; P Lane-Bell; G Srivastava; Ole Hindsgaul; W Paranchych; Robert S Hodges; Randall T Irvin
Fimbria-mediated adherence of Candida albicans to glycosphingolipid receptors on human buccal epithelial cells.
Infection and immunity 1994;62(7):2843-8.
1994: Gwen Y Alton; G Srivastava; kanwal jeet kaur; Ole Hindsgaul
Use of N-acetylglucosaminyltransferases I and II in the synthesis of a dideoxypentasaccharide.
Bioorganic & medicinal chemistry 1994;2(7):675-80.
1994: T L Lowary; S J Swiedler; Ole Hindsgaul
Recognition of synthetic analogues of the acceptor, beta-D-Gal p-OR, by the blood-group H gene-specified glycosyltransferase.
Carbohydrate research 1994;256(2):257-73.
1994: J Y Zhao; Norman J Dovichi; Ole Hindsgaul; S Gosselin; Monica Palcic
Detection of 100 molecules of product formed in a fucosyltransferase reaction.
Glycobiology 1994;4(2):239-42.
1994: H B Sheth; KK Lee; Wah Y Wong; G Srivastava; Ole Hindsgaul; Robert S Hodges; W Paranchych; Randall T Irvin
The pili of Pseudomonas aeruginosa strains PAK and PAO bind specifically to the carbohydrate sequence beta GalNAc(1-4)beta Gal found in glycosphingolipids asialo-GM1 and asialo-GM2.
Molecular microbiology 1994;11(4):715-23.
1994: T L Lowary; Ole Hindsgaul
Recognition of synthetic O-methyl, epimeric, and amino analogues of the acceptor alpha-L-Fuc p-(1-->2)-beta-D-Gal p-OR by the blood-group A and B gene-specified glycosyltransferases.
Carbohydrate research 1994;251():33-67.
1994: Monica Palcic; James Michael Pierce; Ole Hindsgaul
Synthetic neoglycoconjugates in glycosyltransferase assay and purification.
Methods in enzymology 1994;247():215-27.
1993: T L Lowary; Ole Hindsgaul
Recognition of synthetic deoxy and deoxyfluoro analogs of the acceptor alpha-L-Fuc p-(1-->2)-beta-D-Gal p-OR by the blood-group A and B gene-specified glycosyltransferases.
Carbohydrate research 1993;249(1):163-95.
1993: T Linker; S C Crawley; Ole Hindsgaul
Recognition of the acceptor beta-D-GlcpNAc-(1-->2)-alpha-D-Manp- (1-->6)-beta-D-Glcp-OR by N-acetyl-glucosaminyltransferase-V: none of the hydroxyl groups on the Glc-residue are important.
Carbohydrate research 1993;245(2):323-31.
1993: G Srivastava; Ole Hindsgaul; Monica Palcic
Chemical synthesis and kinetic characterization of UDP-2-deoxy-D-lyxo-hexose("UDP-2-deoxy-D-galactose"), a donor-substrate for beta-(1-->4)-D-galactosyltransferase.
Carbohydrate research 1993;245(1):137-44.
1993: R Oehrlein; Ole Hindsgaul; Monica Palcic
Use of the "core-2"-N-acetylglucosaminyltransferase in the chemical-enzymatic synthesis of a sialyl-LeX-containing hexasaccharide found on O-linked glycoproteins.
Carbohydrate research 1993;244(1):149-59.
1993: Osamu Kanie; S C Crawley; Monica Palcic; Ole Hindsgaul
Acceptor-substrate recognition by N-acetylglucosaminyltransferase-V: critical role of the 4"-hydroxyl group in beta-D-GlcpNAc-(1-->2)-alpha-D-Manp(1-->6)-beta-D-Glcp-OR.
Carbohydrate research 1993;243(1):139-64.
1993: S H Khan; S C Crawley; Osamu Kanie; Ole Hindsgaul
A trisaccharide acceptor analog for N-acetylglucosaminyltransferase V which binds to the enzyme but sterically precludes the transfer reaction.
The Journal of biological chemistry 1993;268(4):2468-73.
1992: G Srivastava; kanwal jeet kaur; Ole Hindsgaul; Monica Palcic
Enzymatic transfer of a preassembled trisaccharide antigen to cell surfaces using a fucosyltransferase.
The Journal of biological chemistry 1992;267(31):22356-61.
1992: kanwal jeet kaur; Ole Hindsgaul
Combined chemical-enzymic synthesis of a dideoxypentasaccharide for use in a study of the specificity of N-acetyl-glucosaminyltransferase-III.
Carbohydrate research 1992;226(2):219-31.
1992: M G Shoreibah; Ole Hindsgaul; James Michael Pierce
Purification and characterization of rat kidney UDP-N-acetylglucosamine: alpha-6-D-mannoside beta-1,6-N-acetylglucosaminyltransferase.
The Journal of biological chemistry 1992;267(5):2920-7.
1992: G Srivastava; Ole Hindsgaul
Synthesis of a tetrasaccharide acceptor for use in the assay of UDP-GlcpNAc:beta-D-Galp-(1----4)-beta-D-GlcpNAc (GlcNAc to Gal) beta(1----3)-N-acetylglucosaminyltransferase activity and the pentasaccharide product that would be formed by its enzymic glycosylation.
Carbohydrate research 1992;224():83-93.
1992: L M Keshvara; E M Newton; A H Good; Ole Hindsgaul; Monica Palcic
Enzyme-linked immunosorbent assays for the measurement of blood group A and B glycosyltransferase activities.
Glycoconjugate journal 1992;9(1):16-20.
1991: Ole Hindsgaul
Synthesis of carbohydrates for applications in glycobiology.
Seminars in cell biology 1991;2(5):319-26.
1991: Ole Hindsgaul; kanwal jeet kaur; G Srivastava; M Blaszczyk-Thurin; S C Crawley; L D Heerze; Monica Palcic
Evaluation of deoxygenated oligosaccharide acceptor analogs as specific inhibitors of glycosyltransferases.
The Journal of biological chemistry 1991;266(27):17858-62.
1991: kanwal jeet kaur; Ole Hindsgaul
A simple synthesis of octyl 3,6-di-O-(alpha-D-mannopyranosyl)-beta-D-mannopyranoside and its use as an acceptor for the assay of N-acetylglucosaminyltransferase-I activity.
Glycoconjugate journal 1991;8(2):90-4.
1991: kanwal jeet kaur; Gwen Y Alton; Ole Hindsgaul
Use of N-acetylglucosaminyltransferases I and II in the preparative synthesis of oligosaccharides.
Carbohydrate research 1991;210():145-53.
1991: Monica Palcic; Ole Hindsgaul
Flexibility in the donor substrate specificity of beta 1,4-galactosyltransferase: application in the synthesis of complex carbohydrates.
Glycobiology 1991;1(2):205-9.
1990: G Srivastava; Gwen Y Alton; Ole Hindsgaul
Combined chemical-enzymic synthesis of deoxygenated oligosaccharide analogs: transfer of deoxygenated D-GlcpNAc residues from their UDP-GlcpNAc derivatives using N-acetylglucosaminyltransferase I.
Carbohydrate research 1990;207(2):259-76.
1990: Monica Palcic; J Ripka; kanwal jeet kaur; M Shoreibah; Ole Hindsgaul; James Michael Pierce
Regulation of N-acetylglucosaminyltransferase V activity. Kinetic comparisons of parental, Rous sarcoma virus-transformed BHK, and L-phytohemagglutinin-resistant BHK cells using synthetic substrates and an inhibitory substrate analog.
The Journal of biological chemistry 1990;265(12):6759-69.
1990: Monica Palcic; R M Ratcliffe; L R Lamontagne; A H Good; Gwen Y Alton; Ole Hindsgaul
An enzyme-linked immunosorbent assay for the measurement of Lewis blood-group alpha-(1----4)-fucosyltransferase activity.
Carbohydrate research 1990;196():133-40.
1990: S C Crawley; Ole Hindsgaul; Gwen Y Alton; James Michael Pierce; Monica Palcic
An enzyme-linked immunosorbent assay for N-acetylglucosaminyltransferase-V.
Analytical biochemistry 1990;185(1):112-7.
1989: A A Coleman; Ole Hindsgaul; Monica Palcic
Stereochemistry of copper amine oxidase reactions.
The Journal of biological chemistry 1989;264(33):19500-5.
1989: S C Crawley; Ole Hindsgaul; R M Ratcliffe; L R Lamontagne; Monica Palcic
A plant fucosyltransferase with human Lewis blood-group specificity.
Carbohydrate research 1989;193():249-56.
1989: Monica Palcic; L D Heerze; O P Srivastava; Ole Hindsgaul
A bisubstrate analog inhibitor for alpha(1----2)-fucosyltransferase.
The Journal of biological chemistry 1989;264(29):17174-81.
1989: Monica Palcic; A P Venot; R M Ratcliffe; Ole Hindsgaul
Enzymic synthesis of oligosaccharides terminating in the tumor-associated sialyl-Lewis-a determinant.
Carbohydrate research 1989;190(1):1-11.
1989: V Srivastava; Ole Hindsgaul
Synthesis of the 3"-sulfate ester of beta-D-GalpNAc-(1----4)-beta-D-GlcpNAc-(1----2)-alpha-D-Manp.
Carbohydrate research 1989;185(1):163-9.
1988: O P Srivastava; Ole Hindsgaul; M Shoreibah; James Michael Pierce
Recognition of oligosaccharide substrates by N-acetyl-glucosaminyltransferase-V.
Carbohydrate research 1988;179():137-61.
1988: R U Lemieux; Ole Hindsgaul; P Bird; S Narasimhan; W W Young
The binding of the Lewis-a human blood group determinant by two hybridoma monoclonal anti-Lea antibodies.
Carbohydrate research 1988;178():293-305.
1988: Ole Hindsgaul; S H Tahir; O P Srivastava; James Michael Pierce
The trisaccharide beta-D-GlcpNAc-(1----2)-alpha-D-Manp-(1----6)-beta-D-Manp, as its 8-methoxycarbonyloctyl glycoside, is an acceptor selective for N-acetylglucosaminyltransferase V.
Carbohydrate research 1988;173(2):263-72.
1987: James Michael Pierce; J Arango; S H Tahir; Ole Hindsgaul
Activity of UDP-GlcNAc:alpha-mannoside beta(1,6)N-acetylglucosaminyltransferase (GnT V) in cultured cells using a synthetic trisaccharide acceptor.
Biochemical and biophysical research communications 1987;146(2):679-84.
1983: W W Young; H S Johnson; Y Tamura; K A Karlsson; G Larson; J M Parker; D P Khare; U Spohr; D A Baker; Ole Hindsgaul; R U Lemieux
Characterization of monoclonal antibodies specific for the Lewis a human blood group determinant.
The Journal of biological chemistry 1983;258(8):4890-4.