FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Aroon Hingorani

Research Profile

Concepts & Ideas

Physiology

Chemicals & Drugs

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Anatomy

Disorders

Procedures

Co-author Network

Publications

TOP 3
Reecha Sofat; Nick Wareham; Francesco D'Aiuto; J Ruth Gallimore; Tim Goodship; Svetlana Hakobyan; Timothy R Hughes; Claudia Langenberg; P Patrizia Mangione; B Paul Morgan; Mark B Pepys; Tina Shah; Aroon D Hingorani
Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay.
Philippa J Talmud; John Whittaker; Ros A Whittall; Jackie A Cooper; Olivier S Descamps; Fotios Drenos; Marta Futema; Seamus C Harrison; Aroon D Hingorani; Philip Howard; Frederik Karpe; Mika Kivimaki; Meena Kumari; Claudia Langenberg; Nicholas Lench; Kawah Li; H Andrew W Neil; Sonia Shah; Steve E Humphries
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.
Youna Hu; Gonçalo R Abecasis; Nan Bing; Margaret G Ehm; Aroon D Hingorani; Mika Kivimäki; Meena Kumari; Li Li; Matthew R Nelson; Kijoung Song; Cathie Spino; Philippa J Talmud; Dawn M Waterworth; John C Whittaker; Chun-Fang Xu; Hyun Min Kang
The benefits of using genetic information to design prevention trials.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Aroon Hingorani (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Reecha Sofat; Nick Wareham; Francesco D'Aiuto; J Ruth Gallimore; Tim Goodship; Svetlana Hakobyan; Timothy R Hughes; Claudia Langenberg; P Patrizia Mangione; B Paul Morgan; Mark B Pepys; Tina Shah; Aroon D Hingorani
Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay.
Journal of immunological methods 2013;390(1-2):63-73.
2013: Philippa J Talmud; John Whittaker; Ros A Whittall; Jackie A Cooper; Olivier S Descamps; Fotios Drenos; Marta Futema; Seamus C Harrison; Aroon D Hingorani; Philip Howard; Frederik Karpe; Mika Kivimaki; Meena Kumari; Claudia Langenberg; Nicholas Lench; Kawah Li; H Andrew W Neil; Sonia Shah; Steve E Humphries
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.
Lancet 2013;381(9874):1293-301.
2013: Youna Hu; Gonçalo R Abecasis; Nan Bing; Margaret G Ehm; Aroon D Hingorani; Mika Kivimäki; Meena Kumari; Li Li; Matthew R Nelson; Kijoung Song; Cathie Spino; Philippa J Talmud; Dawn M Waterworth; John C Whittaker; Chun-Fang Xu; Hyun Min Kang
The benefits of using genetic information to design prevention trials.
American journal of human genetics 2013;92(4):547-57.
2013: Tina Shah; Reecha Sofat; Daniel I Swerdlow; Philippa J Talmud; John Whittaker; Delilah Zabaneh; Ian N M Day; Tom R Gaunt; Aroon D Hingorani; Michael Holmes; Steve E Humphries; Mika Kivimaki; Meena Kumari; Sonia Shah; Juan P Casas
Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.
Circulation. Cardiovascular genetics 2013;6(2):163-70.
2013: Sonia Shah; Tina Shah; George Davey Smith; Reecha Sofat; Daniel I Swerdlow; Philippa J Talmud; John Whittaker; Delilah Zabaneh; Juan P Casas; Jackie Cooper; Ian N M Day; Fotios Drenos; Shah Ebrahim; Tom R Gaunt; Aroon D Hingorani; Mika Kivimaki; Meena Kumari; Debbie A Lawlor; Jutta Palmen; Steve E Humphries
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
European heart journal 2013;34(13):972-81.
2013: Sonia Shah; Rona J Strawbridge; Daniel I Swerdlow; Philippa J Talmud; Elena Tremoli; Fabrizio Veglia; Nick Wareham; John Whittaker; Damiano Baldassarre; Juan P Casas; Ulf de Faire; John Deanfield; Fotios Drenos; Karl Gertow; Bruna Gigante; Anders Hamsten; Michael V Holmes; Steve E Humphries; Mika Kivimaki; Meena Kumari; Claudia Langenberg; Bengt Sennblad; Aroon D Hingorani
Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.
Circulation. Cardiovascular genetics 2013;6(1):63-72.
2013: Usha Chakravarthy; Paulus T V M de Jong; Aroon D Hingorani; Gareth J McKay; Mati Rahu; Johan Seland; Reecha Sofat; Gisele SOUBRANE; Laura Tomazzoli; Fotis Topouzis; Johannes Vingerling; Jesús Vioque; Ian S Young; Astrid E Fletcher
ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.
Ophthalmology 2013;120(2):342-8.
2013: Aroon D Hingorani; Karel G M Moons; Richard D Riley; Willi Sauerbrei; Sara Schroter; Ewout W Steyerberg; Daniëlle A van der Windt; Keith Abrams; Douglas G Altman; Harry Hemingway
Prognosis research strategy (PROGRESS) 4: stratified medicine research.
BMJ (Clinical research ed.) 2013;346():e5793.
2012: Spiros C Denaxas; Julie George; Emily Herrett; Aroon D Hingorani; Dipak Kalra; Mika Kivimaki; Anoop D Shah; Liam Smeeth; Adam D Timmis; Harry Hemingway
Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER).
International journal of epidemiology 2012;41(6):1625-38.
2012: Tom R Gaunt; Jules C Hancox; Aroon D Hingorani; Steve E Humphries; Mika Kivimaki; Meena Kumari; Debbie A Lawlor; Peter W Macfarlane; Christopher P Nelson; Nilesh J Samani; Sonia Shah; Philippa J Talmud; Martin D Tobin; Maciej Tomaszewski; John Whittaker; Henggui Zhang; Ismail Adeniran; Antoinette Amuzu; Peter Braund; Paul R Burton; Juan P Casas; Fotios Drenos; Per Eriksson; Lasse Folkersen; Ian N M Day
Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.
Circulation. Cardiovascular genetics 2012;5(6):630-8.
2012: Eleonora Staines-Urias; Pat Doyle; Frank Dudbridge; Aroon D Hingorani; John P A Ioannidis; Brendan J Keating; María C Paez; Norma C Serrano; Juan P Casas
Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis.
International journal of epidemiology 2012;41(6):1764-75.
2012: Seán J Costelloe; Fotios Drenos; Julia S El-Sayed Moustafa; Anna-Liisa Hartikainen; Aroon D Hingorani; Steve E Humphries; Mika Kivimaki; Meena Kumari; Järvelin Marjo-Riitta; Jutta Palmen; Anneli Pouta; Li Qiao; Michael Thomas; Ioanna Tzoulaki; Robin G Walters; Stephen Whiting; Marjo-Riitta Järvelin; Qiao Li; Aimo Ruokonen; Ruokonen Aimo; Alexandra I F Blakemore; Lachlan J M Coin; Philippa J Talmud
Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.
Circulation. Cardiovascular genetics 2012;5(5):555-60.
2012: Aroon D Hingorani; Gordon D Lowe; Jennifer Mindell; Richard W Morris; Naveed Sattar; Reecha Sofat; Peter Whincup; Juan P Casas; Tina Shah
Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease?
European heart journal 2012;33(18):2258-64.
2012: Marcus R Munafò; Sandosh Padmanabhan; Tom M Palmer; David Prieto-Merino; Caroline Relton; Elio Riboli; Naveed Sattar; Maria N Timofeeva; Nicholas J Timpson; George R. Uhl; Mark N Upton; Paolo Vineis; Donna Walther; Graham Watt; Peter H Whincup; Antoinette Amuzu; Paul Aveyard; Paul Brennan; Juan P Casas; Shah Ebrahim; Aroon D Hingorani; Barbara J Jefferis; Paul C D Johnson; Elaine C Johnstone; Richard W Morris; George Davey Smith
Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure.
Journal of the National Cancer Institute 2012;104(10):740-8.
2012: Alexander Jones; Debbie A Lawlor; Stefano Masi; George Davey Smith; Ann E Donald; Emanuela Falaschetti; Nick Finer; Aroon D Hingorani; Marietta Charakida; John E Deanfield
Adipose and height growth through childhood and blood pressure status in a large prospective cohort study.
Hypertension 2012;59(5):919-25.
2012: Shailen Sutaria; Adam Timmis; Keith Abrams; Natalie K Fitzpatrick; Aroon D Hingorani; Santiago G Moreno; Peter Philipson; Harry Hemingway
Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease.
Heart (British Cardiac Society) 2012;98(8):615-22.
2012: Aroon D Hingorani; Juan Pablo Casas
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Lancet 2012;379(9822):1214-24.
2012: Andrew J P Smith; Stefan Stender; Philippa J Talmud; Anne Tybjaerg-Hansen; Per Eriksson; Lasse Folkersen; Claudia Giambartolomei; Aroon D Hingorani; Philip Howard; Meena Kumari; Jutta Palmen; Sonia Shah; Steve E Humphries
Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays.
PLoS genetics 2012;8(8):e1002908.
2012: Ian J Douglas; Stephen J W Evans; Anthony M Grosso; Harry Hemingway; Aroon D Hingorani; Adam Timmis; Liam Smeeth
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
BMJ (Clinical research ed.) 2012;345():e4388.
2012: Diane J Berry; Aroon D Hingorani; Karani S Vimaleswaran; John C Whittaker; Elina Hyppönen
Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.
PloS one 2012;7(5):e37465.
2012: Audrey C Papp; Carl J Pepine; Julia K Pinsonneault; Yan Gong; Aroon D Hingorani; Steve E Humphries; Julie A Johnson; Meena Kumari; Leslie C Newman; Sonia Shah; Philippa J Talmud; Danxin Wang; Wolfgang Sadee
Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.
PloS one 2012;7(3):e31930.
2012: Reecha Sofat; Juan P Casas; Anthony M Grosso; Raymond J MacAllister; Brian N C Prichard; Liam Smeeth; Aroon D Hingorani
Could NICE guidance on the choice of blood pressure lowering drugs be simplified?
BMJ (Clinical research ed.) 2012;344():d8078.
2011: Rachel M Freathy; Andrew T Hattersley; Anita Hill; Aroon D Hingorani; Claus Holst; Barbara J Jefferis; Paul C D Johnson; Gbenga R Kazeem; Sofia I I Kring; Debbie A Lawlor; Vincent Mooser; Richard W Morris; Sandosh Padmanabhan; Lavinia Paternoster; Martin Preisig; Susan M Ring; Naveed Sattar; Thorkild I A Sørensen; Federica Tozzi; Mark N Upton; Peter Vollenweider; Gerard Waeber; Graham Watt; Peter H Whincup; George Davey Smith; Shah Ebrahim; Timothy M Frayling; Marcus Munafò
Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index.
International journal of epidemiology 2011;40(6):1617-28.
2011: Delilah Zabaneh; Juan P Casas; Robert Clarke; Fotios Drenos; Gerry Fowkes; Aroon D Hingorani; Jemma Hopewell; Mika Kivimaki; Florian Kronenberg; Meena Kumari; Claudia Lamina; KaWah Li; Jutta Palmen; Theodore Papamarkou; Bernhard Paulweber; Jackie Price; Manj Sandhu; Shah Sonia; Tina Shah; Marlene Stewart; Monika Summerer; Philippa J Talmud; Nick Wainwright; Nick Wareham; John Whittaker; Steve E Humphries
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
Atherosclerosis 2011;217(2):447-51.
2011: Amy E Taylor; John E Deanfield; Jean Golding; Philip A I Guthrie; Aroon D Hingorani; Naveed Sattar; George Davey Smith; Ian N M Day
IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children.
Biological psychiatry 2011;70(2):152-8.
2011: Philippa J Talmud; J Whittaker; M Kivimaki; Meena Kumari; Debbie A Lawlor; Jutta Palmen; Shah Sonia; Tina Shah; J P Casas; Jackie A Cooper; Ian N M Day; Fotios Drenos; T Gaunt; Aroon D Hingorani; Michael Holmes; Steve E Humphries
Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies.
Diabetologia 2011;54(7):1710-9.
2011: Anoop D Shah; Adam D Timmis; Aroon D Hingorani; Owen Nicholas; Keith Abrams; Ruoling Chen; Gene Feder; Harry Hemingway
Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis.
PLoS medicine 2011;8(5):e1000439.
2011: Anders C Jensen; Adam Barker; Meena Kumari; Eric J Brunner; Mika Kivimäki; Aroon D Hingorani; Nicholas J Wareham; Adam G Tabák; Daniel R Witte; Claudia Langenberg
Associations of common genetic variants with age-related changes in fasting and postload glucose: evidence from 18 years of follow-up of the Whitehall II cohort.
Diabetes 2011;60(5):1617-23.
2011: Anthony Grosso; Ian Douglas; Raymond MacAllister; Irene Petersen; Liam Smeeth; Aroon D Hingorani
Use of the self-controlled case series method in drug safety assessment.
Expert opinion on drug safety 2011;10(3):337-40.
2011: Michael V Holmes; Seamus Harrison; Philippa J Talmud; Aroon D Hingorani; Steve E Humphries
Utility of genetic determinants of lipids and cardiovascular events in assessing risk.
Nature reviews. Cardiology 2011;8(4):207-21.
2011: Michael Holmes; Juan P Casas; Aroon D Hingorani
Putting genomics into practice.
BMJ (Clinical research ed.) 2011;343():d4953.
2011: Aroon D Hingorani; Harry Hemingway
How should we balance individual and population benefits of statins for preventing cardiovascular disease?
BMJ (Clinical research ed.) 2011;342():c6244.
2010: Emanuela Falaschetti; Aroon D Hingorani; Alexander Jones; Marietta Charakida; Nick Finer; Peter Whincup; Debbie A Lawlor; George Davey Smith; Naveed Sattar; John E Deanfield
Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children.
European heart journal 2010;31(24):3063-72.
2010: Lila Mayahi; Lydia Mason; Katherine Bleasdale-Barr; Ann Donald; Iris Trender-Gerhard; Mary G Sweeney; Mary B Davis; Nicholas Wood; Christopher J Mathias; Laura Watson; Denis Pellerin; Simon Heales; John E Deanfield; Kailash Bhatia; Judith Murray-Rust; Aroon D Hingorani
Endothelial, sympathetic, and cardiac function in inherited (6R)-L-erythro-5,6,7,8-tetrahydro-L-biopterin deficiency.
Circulation. Cardiovascular genetics 2010;3(6):513-22.
2010: Georgios Tsakos; Wael Sabbah; Aroon D Hingorani; Gopalakrishnan Netuveli; Nikos Donos; Richard G Watt; Francesco D'Aiuto
Is periodontal inflammation associated with raised blood pressure? Evidence from a National US survey.
Journal of hypertension 2010;28(12):2386-93.
2010: Gie Ken-Dror; Fotios Drenos; Steve E Humphries; Philippa J Talmud; Aroon D Hingorani; M Kivimäki; Meena Kumari; Kenneth A Bauer; James Morrissey; H A Ireland
Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.
Journal of thrombosis and haemostasis : JTH 2010;8(11):2394-403.
2010: Reecha Sofat; Juan P Casas; Meena Kumari; Philippa J Talmud; Helen Ireland; Mika Kivimaki; Michael Marmot; Alun D Hughes; Simon Thom; Shah Ebrahim; John C Whittaker; Liam Smeeth; Debbie A Lawlor; Steve E Humphries; Aroon D Hingorani
Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.
Atherosclerosis 2010;213(1):184-90.
2010: Caroline Minassian; Francesco D'Aiuto; Aroon D Hingorani; Liam Smeeth
Invasive dental treatment and risk for vascular events: a self-controlled case series.
Annals of internal medicine 2010;153(8):499-506.
2010: Tina Shah; Paul Newcombe; Liam Smeeth; Juliet Addo; Juan P Casas; John Whittaker; Michelle A Miller; Lorna Tinworth; Steve Jeffery; Pasquale Strazzullo; Francesco P Cappuccio; Aroon D Hingorani
Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction.
Circulation. Cardiovascular genetics 2010;3(5):436-44.
2010: Adrian Sayers; Nicholas J Timpson; Naveed Sattar; John Deanfield; Aroon D Hingorani; George Davey Smith; Jonathan H Tobias
Adiponectin and its association with bone mass accrual in childhood.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(10):2212-20.
2010: Muna Noori; Ann E Donald; Aspasia Angelakopoulou; Aroon D Hingorani; David J Williams
Prospective study of placental angiogenic factors and maternal vascular function before and after preeclampsia and gestational hypertension.
Circulation 2010;122(5):478-87.
2010: Liam Smeeth; Aroon D Hingorani
Short-term vascular risk: time to take notice?
Nature reviews. Cardiology 2010;7(7):409-11.
2010: Harry Hemingway; Peter Philipson; Ruoling Chen; Natalie K Fitzpatrick; Jacqueline Damant; Martin Shipley; Keith Abrams; Santiago Moreno; Kate S L McAllister; Stephen Palmer; Juan Carlos Kaski; Adam D Timmis; Aroon D Hingorani
Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease.
PLoS medicine 2010;7(6):e1000286.
2010: Juan P Casas; Ewa Ninio; Andrie Panayiotou; Jutta Palmen; Jackie A Cooper; Sally L Ricketts; Reecha Sofat; Andrew N Nicolaides; James P Corsetti; F Gerry R Fowkes; Ioanna Tzoulaki; Meena Kumari; Eric J Brunner; Mika Kivimaki; Michael G Marmot; Michael M Hoffmann; Karl Winkler; Winfred März; Shu Ye; Heide A Stirnadel; S Matthijs Boekholdt; Kay-Tee Khaw; Steve E Humphries; Manjinder S Sandhu; Aroon D Hingorani; Philippa J Talmud
PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.
Circulation 2010;121(21):2284-93.
2010: Ann E Donald; Marietta Charakida; Emanuela Falaschetti; Debbie A Lawlor; Julian P Halcox; Jean Golding; Aroon D Hingorani; George Davey Smith; John E Deanfield
Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC).
European heart journal 2010;31(12):1502-10.
2010: Nadeem Sarwar; Manjinder S Sandhu; Sally L Ricketts; Adam S Butterworth; Emanuele Di Angelantonio; S Matthijs Boekholdt; Willem H Ouwehand; Hugh Watkins; Nilesh J Samani; Danish Saleheen; Debbie Lawlor; Muredach P Reilly; Aroon D Hingorani; Philippa J Talmud; John Danesh
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.
Lancet 2010;375(9726):1634-9.
2010: Aroon D Hingorani; Tina Shah; Meena Kumari; Reecha Sofat; Liam Smeeth
Translating genomics into improved healthcare.
BMJ (Clinical research ed.) 2010;341():c5945.
2010: Norma C Serrano; Luis A Díaz; Juan P Casas; Aroon D Hingorani; Daniel Moreno de Lucca; María C Páez
Frequency of eNOS polymorphisms in the Colombian general population.
BMC genetics 2010;11():54.
2010: Martin Henriksson; Stephen Palmer; Ruoling Chen; Jacqueline Damant; Natalie K Fitzpatrick; Keith Abrams; Aroon D Hingorani; Ulf Stenestrand; Magnus Janzon; Gene Feder; Bruce Keogh; Martin J Shipley; Juan-Carlos Kaski; Adam Timmis; Mark Sculpher; Harry Hemingway
Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery.
BMJ (Clinical research ed.) 2010;340():b5606.
2010: Philippa J Talmud; Aroon D Hingorani; Jackie A Cooper; Michael G Marmot; Eric J Brunner; Meena Kumari; Mika Kivimäki; Steve E Humphries
Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.
BMJ (Clinical research ed.) 2010;340():b4838.
2010: Paul Welsh; Eliana Polisecki; Michele Robertson; Sabine Jahn; Brendan M Buckley; Anton J M de Craen; Ian Ford; J Wouter Jukema; Peter W Macfarlane; Chris J Packard; David J Stott; Rudi G J Westendorp; James Shepherd; Aroon D Hingorani; George Davey Smith; Ernst Schaefer; Naveed Sattar
Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach.
The Journal of clinical endocrinology and metabolism 2010;95(1):93-9.
2009: Aroon D Hingorani; Bruce M Psaty
Primary prevention of cardiovascular disease: time to get more or less personal?
JAMA : the journal of the American Medical Association 2009;302(19):2144-5.
2009: Anthony Grosso; Ian Douglas; Aroon D Hingorani; Raymond J MacAllister; Richard Hubbard; Liam Smeeth
Inhaled tiotropium bromide and risk of stroke.
British journal of clinical pharmacology 2009;68(5):731-6.
2009: Fotios Drenos; Philippa J Talmud; Juan P Casas; Liam Smeeth; Jutta Palmen; Steve E Humphries; Aroon D Hingorani
Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.
Human molecular genetics 2009;18(12):2305-16.
2009: Leanne Bellamy; Juan-Pablo Casas; Aroon D Hingorani; David Williams
Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis.
Lancet 2009;373(9677):1773-9.
2009: Paul J Newcombe; Claudio Verzilli; Juan P Casas; Aroon D Hingorani; Liam Smeeth; John C Whittaker
Multilocus Bayesian meta-analysis of gene-disease associations.
American journal of human genetics 2009;84(5):567-80.
2009: Sean G O'Neill; Jose M Pego-Reigosa; Aroon D Hingorani; Rupa Bessant; David A Isenberg; Anisur Rahman
Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus.
Rheumatology (Oxford, England) 2009;48(5):573-5.
2009: Naveed Sattar; Aroon D Hingorani
C-reactive protein and prognosis in diabetes: getting to the heart of the matter.
Diabetes 2009;58(4):798-9.
2009: Aroon D Hingorani; Tina Shah; Juan P Casas; Steve E Humphries; Philippa J Talmud
C-reactive protein and coronary heart disease: predictive test or therapeutic target?
Clinical chemistry 2009;55(2):239-55.
2009: Tina Shah; Juan P Casas; Jackie A Cooper; Ioanna Tzoulaki; Reecha Sofat; Valerie McCormack; Liam Smeeth; John E Deanfield; Gordon D Lowe; Ann Rumley; F Gerald R Fowkes; Steve E Humphries; Aroon D Hingorani
Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts.
International journal of epidemiology 2009;38(1):217-31.
2009: Michael V Holmes; Tina Shah; Christine Vickery; Liam Smeeth; Aroon D Hingorani; Juan P Casas
Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.
PloS one 2009;4(12):e7960.
2009: Hannah Kuper; Amanda Nicholson; Mika Kivimaki; Amina Aitsi-Selmi; Gianpiero Cavalleri; John E Deanfield; Peter Heuschmann; Xavier Jouven; Sofia Malyutina; Bongani M Mayosi; Susanna Sans; Troels Thomsen; Jacqueline C M Witteman; Aroon D Hingorani; Debbie A Lawlor; Harry Hemingway
Evaluating the causal relevance of diverse risk markers: horizontal systematic review.
BMJ (Clinical research ed.) 2009;339():b4265.
2008: Makrina D Savvidou; M Noori; J M Anderson; Aroon D Hingorani; Kypros H Nicolaides
Maternal endothelial function and serum concentrations of placental growth factor and soluble endoglin in women with abnormal placentation.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;32(7):871-6.
2008: Francesco D'Aiuto; Wael Sabbah; Gopalakrishnan Netuveli; Nikolaos Donos; Aroon D Hingorani; John Deanfield; Georgios Tsakos
Association of the metabolic syndrome with severe periodontitis in a large U.S. population-based survey.
The Journal of clinical endocrinology and metabolism 2008;93(10):3989-94.
2008: Eric Brunner; Mika Kivimäki; Daniel R Witte; Debbie A Lawlor; George Davey Smith; Jackie A Cooper; Michelle Miller; Gordon D O Lowe; Ann Rumley; Juan P Casas; Tina Shah; Steve E Humphries; Aroon D Hingorani; Michael G Marmot; Nicholas J Timpson; Meena Kumari
Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.
PLoS medicine 2008;5(8):e155.
2008: Claudio Verzilli; Tina Shah; Juan P Casas; Juliet Chapman; Manjinder Sandhu; Sally L Debenham; Matthijs S Boekholdt; Kay-Tee Khaw; Nicholas J Wareham; Richard Judson; Emelia Benjamin; Sekar Kathiresan; Martin G Larson; Jian Rong; Reecha Sofat; Steve E Humphries; Liam Smeeth; Gianpiero Cavalleri; John C Whittaker; Aroon D Hingorani
Bayesian meta-analysis of genetic association studies with different sets of markers.
American journal of human genetics 2008;82(4):859-72.
2008: Robert Clarke; Jonathan R Emberson; Elizabeth Breeze; Juan P Casas; Sarah Parish; Aroon D Hingorani; Astrid Fletcher; Rory Collins; Liam Smeeth
Biomarkers of inflammation predict both vascular and non-vascular mortality in older men.
European heart journal 2008;29(6):800-9.
2008: Aroon D Hingorani; Francesco D'Aiuto
Chronic inflammation, periodontitis and cardiovascular diseases.
Oral diseases 2008;14(2):102-4.
2008: Philippa J Talmud; Jackie A Cooper; Jutta Palmen; Ruth Lovering; Fotios Drenos; Aroon D Hingorani; Steve E Humphries
Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.
Clinical chemistry 2008;54(3):467-74.
2008: Mika Kivimäki; Debbie A Lawlor; George Davey Smith; Meena Kumari; Ann Donald; Annie Britton; Juan P Casas; Tina Shah; Eric Brunner; Nicholas J Timpson; julian halcox; Michelle A Miller; Steve E Humphries; John Deanfield; Michael G Marmot; Aroon D Hingorani
Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study.
PloS one 2008;3(8):e3013.
2007: Leanne Bellamy; Juan-Pablo Casas; Aroon D Hingorani; David J Williams
Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis.
BMJ (Clinical research ed.) 2007;335(7627):974.
2007: Lila Mayahi; Simon J R Heales; David Owen; Juan P Casas; Joanne Harris; Raymond J MacAllister; Aroon D Hingorani
(6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1334-9.
2007: Liam Smeeth; Juan P Casas; Aroon D Hingorani
The role of infection in cardiovascular disease: more support but many questions remain.
European heart journal 2007;28(10):1178-9.
2007: Roshan Ariyaratnam; Juan P Casas; John Whittaker; Liam Smeeth; Aroon D Hingorani; Pankaj Sharma
Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals.
PLoS medicine 2007;4(4):e131.
2007: Maurizio S Tonetti; Francesco D'Aiuto; Luigi Nibali; Ann Donald; Clare Storry; Mohamed Hussein Parkar; Jean Suvan; Aroon D Hingorani; Patrick Vallance; John Deanfield
Treatment of periodontitis and endothelial function.
The New England journal of medicine 2007;356(9):911-20.
2006: Norma C Serrano; Luis Alfonso Díaz; María-Carolina Páez; Clara M Mesa; Rodrigo Cifuentes; Alvaro Monterrosa; Adriana González; Liam Smeeth; Aroon D Hingorani; Juan P Casas
Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias.
PLoS medicine 2006;3(12):e520.
2006: Makrina D Savvidou; C K H Yu; Lisa C Harland; Aroon D Hingorani; Kypros H Nicolaides
Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction.
American journal of obstetrics and gynecology 2006;195(6):1668-73.
2006: Juan P Casas; Gianpiero L Cavalleri; Leonelo E Bautista; Liam Smeeth; Steve E Humphries; Aroon D Hingorani
Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review.
American journal of epidemiology 2006;164(10):921-35.
2006: Leonelo E Bautista; Liam Smeeth; Aroon D Hingorani; Juan P Casas
Estimation of bias in nongenetic observational studies using "mendelian triangulation".
Annals of epidemiology 2006;16(9):675-80.
2006: Juan P Casas; Tina Shah; Jackie Cooper; Emma Hawe; Alex D McMahon; Dairena Gaffney; Chris J Packard; Denis S O'Reilly; Irène Juhan-Vague; John S Yudkin; Elena Tremoli; Maurizio Margaglione; Giovanni Di Minno; Anders Hamsten; Teake Kooistra; Jeffrey W Stephens; Steven J Hurel; Shona J Livingstone; Helen M Colhoun; George J Miller; Leonelo E Bautista; Tom Meade; Naveed Sattar; Steve E Humphries; Aroon D Hingorani
Insight into the nature of the CRP-coronary event association using Mendelian randomization.
International journal of epidemiology 2006;35(4):922-31.
2006: Aroon D Hingorani; Tina Shah; Juan P Casas
Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk.
European heart journal 2006;27(11):1261-3.
2006: J Delgado Alves; Brian R Clapp; Ray Stidwill; P P Chen; Aroon D Hingorani; M Singer; D A Isenberg
Human monoclonal IgG anticardiolipin antibodies induce nitric oxide synthase expression.
Atherosclerosis 2006;185(2):246-53.
2006: Juan P Casas; Jackie Cooper; George J Miller; Aroon D Hingorani; Steve E Humphries
Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies.
Annals of human genetics 2006;70(Pt 2):145-69.
2006: C K H Yu; Juan P Casas; Makrina D Savvidou; Manpreet K Sahemey; Kypros H Nicolaides; Aroon D Hingorani
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis.
BMC pregnancy and childbirth 2006;6():7.
2005: Juan P Casas; Weiliang Chua; Stavros Loukogeorgakis; Patrick Vallance; Liam Smeeth; Aroon D Hingorani; Raymond J MacAllister
Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis.
Lancet 2005;366(9502):2026-33.
2005: LC Jones; Aroon D Hingorani
Genetic regulation of endothelial function.
Heart (British Cardiac Society) 2005;91(10):1275-7.
2005: Francesco D'Aiuto; Juan P Casas; Tina Shah; Steve E Humphries; Aroon D Hingorani; Maurizio S Tonetti
C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus.
Atherosclerosis 2005;179(2):413-7.
2005: Brian R Clapp; Gideon M Hirschfield; Clare Storry; J Ruth Gallimore; Ray Stidwill; Mervyn Singer; John E Deanfield; Raymond J MacAllister; Mark B Pepys; Patrick Vallance; Aroon D Hingorani
Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability.
Circulation 2005;111(12):1530-6.
2005: Juan P Casas; Leonelo E Bautista; Liam Smeeth; Pankaj Sharma; Aroon D Hingorani
Homocysteine and stroke: evidence on a causal link from mendelian randomisation.
Lancet 2005;365(9455):224-32.
2004: Juan P Casas; Aroon D Hingorani; Leonelo E Bautista; Pankaj Sharma
Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.
Archives of neurology 2004;61(11):1652-61.
2004: Norma C Serrano; Juan P Casas; Luis Alfonso Díaz; Carolina Páez; Clara M Mesa; Rodrigo Cifuentes; Alvaro Monterrosa; Alejandro Bautista; Emma Hawe; Aroon D Hingorani; Patrick Vallance; Patricio López-Jaramillo
Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study.
Hypertension 2004;44(5):702-7.
2004: Brian R Clapp; Aroon D Hingorani; Rajesh K Kharbanda; Vidya Mohamed-Ali; Jeffrey W Stephens; Patrick Vallance; Raymond J MacAllister
Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.
Cardiovascular research 2004;64(1):172-8.
2004: Daniel G Healy; Patrick M Abou-Sleiman; Andrew J Lees; Juan P Casas; Niall Quinn; K Bhatia; Aroon D Hingorani; Nicholas W Wood
Tau gene and Parkinson's disease: a case-control study and meta-analysis.
Journal of neurology, neurosurgery, and psychiatry 2004;75(7):962-5.
2004: Aroon D Hingorani
Diet, the endothelium and atherosclerosis.
Clinical science (London, England : 1979) 2004;106(5):447-8.
2004: Juan P Casas; Leonelo E Bautista; Steve E Humphries; Aroon D Hingorani
Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects.
Circulation 2004;109(11):1359-65.
2004: Raymond J MacAllister; Aroon D Hingorani; Juan P Casas
Ximelagatran or warfarin in atrial fibrillation?
Lancet 2004;363(9410):735-6; author reply 736.
2003: LC Jones; Cam T L Tran; James M Leiper; Aroon D Hingorani; Patrick Vallance
Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells.
Biochemical and biophysical research communications 2003;310(3):836-43.
2003: Makrina D Savvidou; Aroon D Hingorani; Dimitrios Tsikas; Juergen Dr.Froelich; Patrick Vallance; Kypros H Nicolaides
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia.
Lancet 2003;361(9368):1511-7.
2003: Aroon D Hingorani
Endothelial nitric oxide synthase polymorphisms and hypertension.
Current hypertension reports 2003;5(1):19-25.
2002: C P M Leeson; Aroon D Hingorani; Michael J Mullen; N Jeerooburkhan; Mia Kattenhorn; Tim J Cole; D P R Muller; Alan Lucas; Steve E Humphries; John E Deanfield
Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function.
Circulation research 2002;90(11):1153-8.
2002: Rajesh K Kharbanda; Benjamin Walton; Meredith Allen; Nigel Klein; Aroon D Hingorani; Raymond J MacAllister; Patrick Vallance
Prevention of inflammation-induced endothelial dysfunction: a novel vasculo-protective action of aspirin.
Circulation 2002;105(22):2600-4.
2002: Norman N Chan; Patrick Vallance; Helen M Colhoun; Raymond J MacAllister; Aroon D Hingorani; Gerard S Conway
The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome.
Clinical endocrinology 2002;56(5):615-20.
2002: Makrina D Savvidou; Christoph C Lees; Mauro Parra; Aroon D Hingorani; Kypros H Nicolaides
Levels of C-reactive protein in pregnant women who subsequently develop pre-eclampsia.
BJOG : an international journal of obstetrics and gynaecology 2002;109(3):297-301.
2001: Makrina D Savvidou; P J Vallance; Kypros H Nicolaides; Aroon D Hingorani
Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy.
Hypertension 2001;38(6):1289-93.
2001: Aroon D Hingorani; N N Chan
D-lactate encephalopathy.
Lancet 2001;358(9295):1814.
2001: N Jeerooburkhan; LC Jones; SR Bujac; Jackie A Cooper; George J Miller; Patrick Vallance; Steve E Humphries; Aroon D Hingorani
Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease.
Hypertension 2001;38(5):1054-61.
2001: Norman N Chan; Raymond J MacAllister; Helen M Colhoun; Patrick Vallance; Aroon D Hingorani
Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women.
The Journal of clinical endocrinology and metabolism 2001;86(6):2499-504.
2000: Aroon D Hingorani; J Cross; Rajesh K Kharbanda; Michael J Mullen; K Bhagat; M Taylor; Ann E Donald; M Palacios; G E Griffin; John E Deanfield; Raymond J MacAllister; Patrick Vallance
Acute systemic inflammation impairs endothelium-dependent dilatation in humans.
Circulation 2000;102(9):994-9.
2000: S Ulrich; Aroon D Hingorani; J Martin; P Vallance
What is the optimal age for starting lipid lowering treatment? A mathematical model.
BMJ (Clinical research ed.) 2000;320(7242):1134-40.
1999: K Bhagat; Aroon D Hingorani; M Palacios; Ian G Charles; Patrick Vallance
Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS.
Cardiovascular research 1999;41(3):754-64.