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David Hinton

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Timothy W Phares; Stephen A Stohlman; David R Hinton; Cornelia C Bergmann
Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis.
Shikun He; Nymph Chan; Xiaohua Li; David R Hinton
Review: Epigenetic mechanisms in ocular disease.
Parameswaran G Sreekumar; Rinku Baid; Paresh Chothe; Vadivel Ganapathy; Nandini Kannan; Ram Kannan; Uday Kompella; Christina Manh; Stephen J Ryan; Krishna K Sharma; Christine Spee; David R Hinton
Antiapoptotic Properties of α-Crystallin-Derived Peptide Chaperones and Characterization of Their Uptake Transporters in Human RPE Cells.

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All Publications

2013: Timothy W Phares; Stephen A Stohlman; David R Hinton; Cornelia C Bergmann
Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis.
Journal of virology 2013;87(6):3382-92.
2013: Shikun He; Nymph Chan; Xiaohua Li; David R Hinton
Review: Epigenetic mechanisms in ocular disease.
Molecular vision 2013;19():665-74.
2013: Parameswaran G Sreekumar; Rinku Baid; Paresh Chothe; Vadivel Ganapathy; Nandini Kannan; Ram Kannan; Uday Kompella; Christina Manh; Stephen J Ryan; Krishna K Sharma; Christine Spee; David R Hinton
Antiapoptotic Properties of α-Crystallin-Derived Peptide Chaperones and Characterization of Their Uptake Transporters in Human RPE Cells.
Investigative ophthalmology & visual science 2013;54(4):2787-98.
2012: Ram Kannan; Parameswaran G Sreekumar; David R Hinton
Novel roles for α-crystallins in retinal function and disease.
Progress in retinal and eye research 2012;31(6):576-604.
2012: Guorui Dou; Shikun He; Ram Kannan; Stephen J Ryan; Christine Spee; Parameswaran G Sreekumar; David R Hinton
Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction.
Free radical biology & medicine 2012;53(5):1111-22.
2012: Jing Xu; Danhong Zhu; Shikun He; Stephen J Ryan; Shozo Sonoda; Christine Spee; David R Hinton
Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9.
Angiogenesis 2012;15(2):213-27.
2012: Timothy W Phares; Stephen A Stohlman; David R Hinton; Cornelia C Bergmann
Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis.
Journal of neuroinflammation 2012;9():269.
2012: Yuntao Hu; Ashish K Ahuja; Dennis O Clegg; Bruno Diniz; Sherry T Hikita; David R Hinton; Lincoln V Johnson; Laura Liu; Bo Lu; Ramiro Ribeiro; Yu-Chong Tai; Biju B Thomas; Padmaja B Thomas; Danhong Zhu; Mark S Humayun
A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer.
Ophthalmic research 2012;48(4):186-91.
2012: Claudia Hindinger; David R Hinton; Shabbir Hussain; Gabriel I Parra; Timothy W Phares; Carine Savarin; Roscoe D Atkinson; Cornelia C Bergmann; Stephen A Stohlman
IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.
PloS one 2012;7(7):e42088.
2012: Carine Savarin; Stephen A Stohlman; Daniel J Cua; David R Hinton; Richard M Ransohoff; Cornelia C Bergmann
IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils.
Journal of neuroinflammation 2012;9():104.
2012: Parameswaran G Sreekumar; Susan P C Cole; Ram Kannan; Stephen J Ryan; Christine Spee; David R Hinton
Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux.
PloS one 2012;7(3):e33420.
2011: Ram Kannan; Parameswaran G Sreekumar; David R Hinton
VEGF and PEDF secretion in ARPE-19 and fhRPE cells.
Investigative ophthalmology & visual science 2011;52(12):9047.
2011: Parameswaran G Sreekumar; David R Hinton; Ram Kannan
Methionine sulfoxide reductase A: Structure, function and role in ocular pathology.
World journal of biological chemistry 2011;2(8):184-92.
2011: Shweta S Puntambekar; Carine Savarin; Cornelia C Bergmann; David R Hinton; Christopher L Karp; Gabriel I Parra; Timothy W Phares; Stephen A Stohlman
Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis.
Journal of virology 2011;85(13):6702-13.
2011: Cristina P Marques; Stephen L Nutt; Timothy W Phares; Richard M Ransohoff; Stephen A Stohlman; Claudia Hindinger; David R Hinton; Parul Kapil; Cornelia C Bergmann
CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis.
Journal of virology 2011;85(13):6136-47.
2011: Jing Xu; Danhong Zhu; Shikun He; Stephen J Ryan; Christine Spee; David R Hinton
Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(7):2221-33.
2011: Theodore R Sadler; Peter T Nguyen; Jun Yang; Tina K Givrad; Emeran A Mayer; Jean-Michel I Maarek; David R Hinton; Daniel P Holschneider
Antenatal maternal stress alters functional brain responses in adult offspring during conditioned fear.
Brain research 2011;1385():163-74.
2011: Timothy W Phares; Cristina P Marques; Stephen A Stohlman; David R Hinton; Cornelia C Bergmann
Factors supporting intrathecal humoral responses following viral encephalomyelitis.
Journal of virology 2011;85(6):2589-98.
2011: Paresh P Chothe; Jaya P Gnana-Prakasam; Sudha Ananth; Pamela Moore Martin; Ram Kannan; David R Hinton; Sylvia B Smith; Vadivel Ganapathy
Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis.
Biochemical and biophysical research communications 2011;405(2):244-9.
2010: Risheng Ye; Olga A Mareninova; Ernesto Barron; Miao Wang; David R Hinton; Stephen J Pandol; Amy S Lee
Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis.
The American journal of pathology 2010;177(6):2827-36.
2010: Usha Gundimeda; Tom McNeill; Jason E Schiffman; David R Hinton; Rayudu Gopalakrishna
Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
Journal of neuroscience research 2010;88(16):3644-55.
2010: Timothy W Phares; Stephen A Stohlman; David R Hinton; Roscoe Atkinson; Cornelia C Bergmann
Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5607-18.
2010: DanHong Zhu; Parameswaran G Sreekumar; David R Hinton; Ram Kannan
Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.
Vision research 2010;50(7):643-51.
2010: Gabriel I Parra; Cornelia C Bergmann; Timothy W Phares; David R Hinton; Roscoe Atkinson; Stephen A Stohlman
Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection.
Journal of virology 2010;84(6):3111-5.
2010: M Wang; R Ye; Ernesto Barron; Peter Baumeister; Changhui Mao; Shengzhan Luo; Y Fu; B Luo; L Dubeau; David R Hinton; Amy S Lee
Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.
Cell death and differentiation 2010;17(3):488-98.
2010: Parameswaran G Sreekumar; Ram Kannan; Mizuki Kitamura; Christine Spee; Ernesto Barron; Stephen J Ryan; David R Hinton
αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells.
PloS one 2010;5(10):e12578.
2010: Shozo Sonoda; Parameswaran G Sreekumar; Satoru Kase; Christine Spee; Stephen J Ryan; Ram Kannan; David R Hinton
Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration.
Aging 2010;2(1):28-42.
2010: Jiehao Zhou; Shikun He; Ning Zhang; Christine Spee; Peng Zhou; Stephen J Ryan; Ram Kannan; David R Hinton
Neutrophils compromise retinal pigment epithelial barrier integrity.
Journal of biomedicine & biotechnology 2010;2010():289360.
2010: Shikun He; S Ram Kumar; Peng Zhou; Valery Krasnoperov; Stephen J Ryan; parkash Gill; David R Hinton
Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro.
Investigative ophthalmology & visual science 2010;51(1):543-52.
2010: Paresh P Chothe; Santoshanand V Thakkar; Jaya P Gnana-Prakasam; Sudha Ananth; David R Hinton; Ram Kannan; Sylvia B Smith; Pamela Moore Martin; Vadivel Ganapathy
Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2010;51(1):413-20.
2009: Danhong Zhu; Xuemei Deng; Jing Xu; David R Hinton
What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence.
Aging 2009;1(8):740-5.
2009: Yeong Hoon Kim; Shikun He; Satoru Kase; Mizuki Kitamura; Stephen J Ryan; David R Hinton
Regulated secretion of complement factor H by RPE and its role in RPE migration.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2009;247(5):651-9.
2009: Danhong Zhu; Jian Wu; Christine Spee; Stephen J Ryan; David R Hinton
BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.
The Journal of biological chemistry 2009;284(14):9529-39.
2009: Parameswaran G Sreekumar; Yi Ding; Stephen J Ryan; Ram Kannan; David R Hinton
Regulation of thioredoxin by ceramide in retinal pigment epithelial cells.
Experimental eye research 2009;88(3):410-7.
2009: Aditi Ray; Leonardo Colodetti; James David Weiland; David R Hinton; Mark S Humayun; Eun-Jin Lee
Immunocytochemical analysis of retinal neurons under electrical stimulation.
Brain research 2009;1255():89-97.
2009: Shozo Sonoda; Christine Spee; Ernesto Barron; Stephen J Ryan; Ram Kannan; David R Hinton
A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells.
Nature protocols 2009;4(5):662-73.
2008: Carine Savarin; Cornelia C Bergmann; David R Hinton; Richard M Ransohoff; Stephen A Stohlman
Memory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis.
Journal of virology 2008;82(24):12432-40.
2008: J Li; M Ni; B Lee; Ernesto Barron; David R Hinton; A S Lee
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells.
Cell death and differentiation 2008;15(9):1460-71.
2008: Shikun He; Youxin Chen; Rima Khankan; Ernesto Barron; Richard Burton; Danhong Zhu; Stephen J Ryan; Noelynn Oliver; David R Hinton
Connective tissue growth factor as a mediator of intraocular fibrosis.
Investigative ophthalmology & visual science 2008;49(9):4078-88.
2008: Shikun He; Jennifer Yaung; Yeong Hoon Kim; Ernesto Barron; Stephen J Ryan; David R Hinton
Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2008;246(5):677-83.
2008: Parameswaran G Sreekumar; Jiehao Zhou; Joonhong Sohn; Christine Spee; Stephen J Ryan; Barry J Maurer; Ram Kannan; David R Hinton
N-(4-hydroxyphenyl) retinamide augments laser-induced choroidal neovascularization in mice.
Investigative ophthalmology & visual science 2008;49(3):1210-20.
2008: Stephen A Stohlman; David R Hinton; Beatriz Parra; Roscoe Atkinson; Cornelia C Bergmann
CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus.
Journal of virology 2008;82(5):2130-9.
2008: Jennifer Yaung; Ram Kannan; Eric F Wawrousek; Christine Spee; Parameswaran G Sreekumar; David R Hinton
Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia.
Experimental eye research 2008;86(2):355-65.
2007: L Colodetti; James David Weiland; S Colodetti; A Ray; Magdalene J Seiler; David R Hinton; Mark S Humayun
Pathology of damaging electrical stimulation in the retina.
Experimental eye research 2007;85(1):23-33.
2007: Jennifer Yaung; Manlin Jin; Ernesto Barron; Christine Spee; Eric F Wawrousek; Ram Kannan; David R Hinton
alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress.
Molecular vision 2007;13():566-77.
2007: Rajat Agrawal; Shikun He; Christine Spee; Jing Z Cui; Stephen J Ryan; David R Hinton
In vivo models of proliferative vitreoretinopathy.
Nature protocols 2007;2(1):67-77.
2007: Nicole Tedeschi-Blok; Jonathan Buckley; Rohit Varma; Timothy Triche; David R Hinton
Population-based study of early age-related macular degeneration: role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease.
Ophthalmology 2007;114(1):99-103.
2006: Shikun He; Francesca Incardona; Manlin Jin; Stephen J Ryan; David R Hinton
Thrombospondin-1 expression in RPE and choroidal neovascular membranes.
Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu 2006;22(4):265-74.
2006: Claudia Hindinger; David R Hinton; Stefanie J Kirwin; Roscoe D Atkinson; Margaret E Burnett; Cornelia C Bergmann; Stephen A Stohlman
Liver X receptor activation decreases the severity of experimental autoimmune encephalomyelitis.
Journal of neuroscience research 2006;84(6):1225-34.
2006: Stefanie J Kirwin; Kennichi C Dowdell; Claudia Hindinger; Ni Feng; Cornelia C Bergmann; David R Hinton; Stephen A Stohlman
Altered neuroantigen-specific cytokine secretion in a Th2 environment reduces experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2006;178(1-2):30-9.
2006: Parameswaran G Sreekumar; Ram Kannan; Aruni T de Silva; Richard Burton; Stephen J Ryan; David R Hinton
Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells.
Biochemical and biophysical research communications 2006;346(4):1200-6.
2006: Maria-Andreea Gamulescu; Youxin Chen; Shikun He; Christine Spee; Manlin Jin; Stephen J Ryan; David R Hinton
Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor.
Experimental eye research 2006;83(1):212-22.
2006: Jun Zuo; Stephen A Stohlman; Jason B Hoskin; David R Hinton; Roscoe Atkinson; Cornelia C Bergmann
Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells.
Virology 2006;350(1):206-15.
2006: Stephan Hoffmann; Shikun He; Marianne Ehren; Stephen J Ryan; Peter Wiedemann; David R Hinton
MMP-2 and MMP-9 secretion by rpe is stimulated by angiogenic molecules found in choroidal neovascular membranes.
Retina (Philadelphia, Pa.) 2006;26(4):454-61.
2006: John M González; Cornelia C Bergmann; John M Gonzalez; David R Hinton; Roscoe Atkinson; Jason Hoskin; Wendy B Macklin; Stephen A Stohlman
Inhibition of interferon-gamma signaling in oligodendroglia delays coronavirus clearance without altering demyelination.
The American journal of pathology 2006;168(3):796-804.
2006: Shuen-Ing Tschen; Stephen A Stohlman; Chandran Ramakrishna; David R Hinton; Roscoe D Atkinson; Cornelia C Bergmann
CNS viral infection diverts homing of antibody-secreting cells from lymphoid organs to the CNS.
European journal of immunology 2006;36(3):603-12.
2006: Masanori Hangai; Shikun He; Stephan Hoffmann; Jennifer I Lim; Stephen J Ryan; David R Hinton
Sequential induction of angiogenic growth factors by TNF-alpha in choroidal endothelial cells.
Journal of neuroimmunology 2006;171(1-2):45-56.
2006: Ram Kannan; Ning Zhang; Parameswaran G Sreekumar; Christine Spee; Anthony Rodriguez; Ernesto Barron; David R Hinton
Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells.
Molecular vision 2006;12():1649-59.
2006: Ning Zhang; Ram Kannan; Curtis T Okamoto; Stephen J Ryan; Vincent H L Lee; David R Hinton
Characterization of brimonidine transport in retinal pigment epithelium.
Investigative ophthalmology & visual science 2006;47(1):287-94.
2005: Jennifer I Lim; Christine Spee; Masanori Hangai; Jorge Rocha; Howard S Ying; Stephen J Ryan; David R Hinton
Neuropilin-1 expression by endothelial cells and retinal pigment epithelial cells in choroidal neovascular membranes.
American journal of ophthalmology 2005;140(6):1044-1050.
2005: Shikun He; Yi Ding; Jiehao Zhou; Valery Krasnoperov; Sergey Zozulya; S Ram Kumar; Stephen J Ryan; parkash Gill; David R Hinton
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization.
Investigative ophthalmology & visual science 2005;46(12):4772-9.
2005: Manlin Jin; Jennifer Yaung; Ram Kannan; Shikun He; Stephen J Ryan; David R Hinton
Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion.
Investigative ophthalmology & visual science 2005;46(11):4311-9.
2005: Judong Pan; Musaad Al-Dubaib; Chun-Peng Liao; Yasuhito Fujino; David R Hinton; Kathleen A Hayes; Lawrence E Mathes; Pradip Roy-Burman
In vivo expression of GFP transgene delivered via a replicating feline leukemia virus.
Veterinary microbiology 2005;110(3-4):181-95.
2005: John M Gonzalez; John M Gonzalez; Cornelia C Bergmann; Babette Fuss; David R Hinton; Roscoe D Atkinson; Wendy B Macklin; Stephen A Stohlman
Astrocyte expression of a dominant-negative interferon-gamma receptor.
Journal of neuroscience research 2005;82(1):20-31.
2005: Parameswaran G Sreekumar; Ram Kannan; Jennifer Yaung; Christine Spee; Stephen J Ryan; David R Hinton
Protection from oxidative stress by methionine sulfoxide reductases in RPE cells.
Biochemical and biophysical research communications 2005;334(1):245-53.
2005: John M González; Cornelia C Bergmann; Babette Fuss; David R Hinton; John M Gonzalez; Wendy B Macklin; Stephen A Stohlman
Expression of a dominant negative IFN-gammareceptor on mouse oligodendrocytes.
Glia 2005;51(1):22-34.
2005: Candy K Chan; Lucia N Pham; Jiehao Zhou; Christine Spee; Stephen J Ryan; David R Hinton
Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization.
Laboratory investigation; a journal of technical methods and pathology 2005;85(6):721-33.
2005: Jiehao Zhou; Norman W Marten; Cornelia C Bergmann; Wendy B Macklin; David R Hinton; Stephen A Stohlman
Expression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.
Journal of virology 2005;79(8):4764-73.
2005: Jiehao Zhou; Lucia N Pham; Ning Zhang; Shikun He; Maria-Andreea Gamulescu; Christine Spee; Stephen J Ryan; David R Hinton
Neutrophils promote experimental choroidal neovascularization.
Molecular vision 2005;11():414-24.
2005: Stephan Hoffmann; Shikun He; Manlin Jin; Marianne Ehren; Peter Wiedemann; Stephen J Ryan; David R Hinton
A selective cyclic integrin antagonist blocks the integrin receptors alphavbeta3 and alphavbeta5 and inhibits retinal pigment epithelium cell attachment, migration and invasion.
BMC ophthalmology 2005;5():16.
2005: Jiehao Zhou; David R Hinton; Stephen A Stohlman; Chih-Pin Liu; Lingwen Zhong; Norman W Marten
Maintenance of CD8+ T cells during acute viral infection of the central nervous system requires CD4+ T cells but not interleukin-2.
Viral immunology 2005;18(1):162-9.
2004: Chandran Ramakrishna; Stephen A Stohlman; Roscoe A Atkinson; David R Hinton; Cornelia C Bergmann
Differential regulation of primary and secondary CD8+ T cells in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6265-73.
2004: Ram Kannan; ManLin Jin; Maria-Andreea Gamulescu; David R Hinton
Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor.
Free radical biology & medicine 2004;37(2):166-75.
2004: Leslie P Weiner; Katherine A Louie; Lilly R Atalla; Harold H Kochounian; Jing Du; Wenqiang Wei; David R Hinton; Erlinda M Gordon; W French Anderson; Minnie McMillan
Gene therapy in a murine model for clinical application to multiple sclerosis.
Annals of neurology 2004;55(3):390-9.
2004: David R Hinton; Christine Spee; Shikun He; Stephen Weitz; William Usinger; Laurie Labree; Noelynn Oliver; Jennifer I Lim
Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy.
Diabetes care 2004;27(3):758-64.
2004: Cornelia C Bergmann; Beatriz Parra; David R Hinton; Chandran Ramakrishna; Kennichi C Dowdell; Stephen A Stohlman
Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cells.
Journal of virology 2004;78(4):1739-50.
2004: Candy K Chan; Lucia N Pham; Cynthia Chinn; Christine Spee; Stephen J Ryan; Rosemary J Akhurst; David R Hinton
Mouse strain-dependent heterogeneity of resting limbal vasculature.
Investigative ophthalmology & visual science 2004;45(2):441-7.
2004: Manlin Jin; Youxin Chen; Shikun He; Stephen J Ryan; David R Hinton
Hepatocyte growth factor and its role in the pathogenesis of retinal detachment.
Investigative ophthalmology & visual science 2004;45(1):323-9.
2003: Zarir E Karanjawala; David R Hinton; Euikyun Oh; Chih-Lin Hsieh; Michael R Lieber
Developmental retinal apoptosis in Ku86-/- mice.
DNA repair 2003;2(12):1429-34.
2003: Shikun He; Man Lin Jin; Vanessa Worpel; David R Hinton
A role for connective tissue growth factor in the pathogenesis of choroidal neovascularization.
Archives of ophthalmology 2003;121(9):1283-8.
2003: Jiehao Zhou; Stephen A Stohlman; David R Hinton; Norman W Marten
Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3331-6.
2003: Cornelia C Bergmann; Beatriz Parra; David R Hinton; Ramakrishna Chandran; Maureen Morrison; Stephen A Stohlman
Perforin-mediated effector function within the central nervous system requires IFN-gamma-mediated MHC up-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):3204-13.
2002: Stephen A Stohlman; Chandran Ramakrishna; Shuen-Ing Tschen; David R Hinton; Cornelia C Bergmann
The art of survival during viral persistence.
Journal of neurovirology 2002;8 Suppl 2():53-8.
2002: Manlin Jin; Ernesto Barron; Shikun He; Stephen J Ryan; David R Hinton
Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor.
Investigative ophthalmology & visual science 2002;43(8):2782-90.
2002: Jiehao Zhou; Stephen A Stohlman; Roscoe Atkinson; David R Hinton; Norman W Marten
Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection.
Journal of virology 2002;76(15):7374-84.
2002: David R Hinton; Shikun He; Man Lin Jin; Ernesto Barron; Stephen J Ryan
Novel growth factors involved in the pathogenesis of proliferative vitreoretinopathy.
Eye (London, England) 2002;16(4):422-8.
2002: Zarir E Karanjawala; Niamh Murphy; David R Hinton; Chih-Lin Hsieh; Michael R Lieber
Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants.
Current biology : CB 2002;12(5):397-402.
2001: Rizwan Masood; Jie Cai; T Zheng; D Lynne Smith; David R Hinton; parkash Gill
Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors.
Blood 2001;98(6):1904-13.
2001: Masanori Hangai; Y S Moon; N Kitaya; Candy K Chan; D Y Wu; K G Peters; Stephen J Ryan; David R Hinton
Systemically expressed soluble Tie2 inhibits intraocular neovascularization.
Human gene therapy 2001;12(10):1311-21.
2001: Masanori Hangai; T Murata; N Miyawaki; Christine Spee; Jennifer I Lim; Shikun He; David R Hinton; Stephen J Ryan
Angiopoietin-1 upregulation by vascular endothelial growth factor in human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2001;42(7):1617-25.
2001: T Murata; Y Hata; T Ishibashi; S Kim; Willa A Hsueh; Ronald E Law; David R Hinton
Response of experimental retinal neovascularization to thiazolidinediones.
Archives of ophthalmology 2001;119(5):709-17.
2001: Erlinda M Gordon; ZH Chen; L Liu; MD Whitley; L Liu; D Wei; Susan Groshen; David R Hinton; W French Anderson; Robert W Beart; Frederick L Hall
Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice.
Human gene therapy 2001;12(2):193-204.
2001: Norman W Marten; M Hohman; Stephen A Stohlman; Roscoe D Atkinson; David R Hinton; Cornelia C Bergmann
Acute CNS infection is insufficient to mediate chronic T cell retention.
Advances in experimental medicine and biology 2001;494():349-54.
2001: Beatriz Parra; Cornelia C Bergmann; David R Hinton; Roscoe Atkinson; Stephen A Stohlman
IFN-gamma secreted by virus-specific CD8+ T cells contribute to CNS viral clearance.
Advances in experimental medicine and biology 2001;494():335-40.
2001: Jiehao Zhou; Stephen A Stohlman; Norman W Marten; David R Hinton
Regulation of matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) genes during JHMV infection of the central nervous system.
Advances in experimental medicine and biology 2001;494():329-34.
2001: Cornelia C Bergmann; Norman W Marten; David R Hinton; Beatriz Parra; Stephen A Stohlman
CD8 T cell mediated immunity to neurotropic MHV infection.
Advances in experimental medicine and biology 2001;494():299-308.
2001: Stephen A Stohlman; David R Hinton
Viral induced demyelination.
Brain pathology (Zurich, Switzerland) 2001;11(1):92-106.
2000: Manlin Jin; Shikun He; V Wörpel; Stephen J Ryan; David R Hinton
Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha.
Investigative ophthalmology & visual science 2000;41(13):4324-32.
2000: Erlinda M Gordon; Peng X Liu; ZH Chen; L Liu; MD Whitley; C Gee; Susan Groshen; David R Hinton; Robert W Beart; Frederick L Hall
Inhibition of metastatic tumor growth in nude mice by portal vein infusions of matrix-targeted retroviral vectors bearing a cytocidal cyclin G1 construct.
Cancer research 2000;60(13):3343-7.
2000: S Hoffmann; R Masood; Y Zhang; S He; Stephen J Ryan; P Gill; David R Hinton
Selective killing of RPE with a vascular endothelial growth factor chimeric toxin.
Investigative ophthalmology & visual science 2000;41(8):2389-93.
2000: T Murata; Shikun He; Masanori Hangai; T Ishibashi; XP Xi; Sangduk Kim; Willa A Hsueh; Stephen J Ryan; Ronald E Law; David R Hinton
Peroxisome proliferator-activated receptor-gamma ligands inhibit choroidal neovascularization.
Investigative ophthalmology & visual science 2000;41(8):2309-17.
2000: T Murata; J Cui; K E Taba; J Y Oh; Christine Spee; David R Hinton; Stephen J Ryan
The possibility of gene therapy for the treatment of choroidal neovascularization.
Ophthalmology 2000;107(7):1364-73.
2000: Norman W Marten; Stephen A Stohlman; Roscoe D Atkinson; David R Hinton; J O Fleming; Cornelia C Bergmann
Contributions of CD8+ T cells and viral spread to demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4080-8.
2000: Jing Z Cui; H Kimura; Christine Spee; Gabriele Thumann; David R Hinton; Stephen J Ryan
Natural history of choroidal neovascularization induced by vascular endothelial growth factor in the primate.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2000;238(4):326-33.
2000: Beatriz Parra; MT Lin; Stephen A Stohlman; Cornelia C Bergmann; Roscoe Atkinson; David R Hinton
Contributions of Fas-Fas ligand interactions to the pathogenesis of mouse hepatitis virus in the central nervous system.
Journal of virology 2000;74(5):2447-50.
2000: Jie Cai; T Zheng; Rizwan Masood; D Lynne Smith; David R Hinton; C N Kim; G Fang; Kapil N Bhalla; parkash Gill
Paclitaxel Induces Apoptosis in AIDS-Related Kaposi's Sarcoma Cells.
Sarcoma 2000;4(1-2):37-45.
1999: Stephen A Stohlman; L Pei; Daniel J Cua; Z Li; David R Hinton
Activation of regulatory cells suppresses experimental allergic encephalomyelitis via secretion of IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):6338-44.
1999: M W Zhao; Man Lin Jin; Shikun He; Christine Spee; Stephen J Ryan; David R Hinton
A distinct integrin-mediated phagocytic pathway for extracellular matrix remodeling by RPE cells.
Investigative ophthalmology & visual science 1999;40(11):2713-23.
1999: RK Kundu; Frank O Sangiorgi; Lan-Ying Wu; Paul K Pattengale; David R Hinton; parkash Gill; Robert E Maxson
Expression of the human immunodeficiency virus-Tat gene in lymphoid tissues of transgenic mice is associated with B-cell lymphoma.
Blood 1999;94(1):275-82.
1999: MT Lin; David R Hinton; Norman W Marten; Cornelia C Bergmann; Stephen A Stohlman
Antibody prevents virus reactivation within the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7358-68.
1999: A M Casella; K E Taba; H Kimura; Christine Spee; J A Cardillo; Stephen J Ryan; David R Hinton
Retinal pigment epithelial cells are heterogeneous in their expression of MHC-II after stimulation with interferon-gamma.
Experimental eye research 1999;68(4):423-30.
1999: Florence M Hofman; P Chen; Francesca Incardona; Raphael Zidovetzki; David R Hinton
HIV-1 tat protein induces the production of interleukin-8 by human brain-derived endothelial cells.
Journal of neuroimmunology 1999;94(1-2):28-39.
1999: Beatriz Parra; David R Hinton; Norman W Marten; Cornelia C Bergmann; MT Lin; C S Yang; Stephen A Stohlman
IFN-gamma is required for viral clearance from central nervous system oligodendroglia.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1641-7.
1999: H Kimura; Christine Spee; Taiji Sakamoto; David R Hinton; Y Ogura; Y Tabata; Y Ikada; Stephen J Ryan
Cellular response in subretinal neovascularization induced by bFGF-impregnated microspheres.
Investigative ophthalmology & visual science 1999;40(2):524-8.
1998: T Murata; Masanori Hangai; T Ishibashi; Christine Spee; Erlinda M Gordon; W French Anderson; David R Hinton; Stephen J Ryan
Retrovirus-mediated gene transfer to photocoagulation-induced choroidal neovascular membranes.
Investigative ophthalmology & visual science 1998;39(12):2474-8.
1998: S Hoffmann; Christine Spee; T Murata; Jing Z Cui; Stephen J Ryan; David R Hinton
Rapid isolation of choriocapillary endothelial cells by Lycopersicon esculentum-coated Dynabeads.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(10):779-84.
1998: P M He; Shikun He; Judy A Garner; Stephen J Ryan; David R Hinton
Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor.
Biochemical and biophysical research communications 1998;249(1):253-7.
1998: S Hoffman; Rayudu Gopalakrishna; Usha Gundimeda; T Murata; Christine Spee; Stephen J Ryan; David R Hinton
Verapamil inhibits proliferation, migration and protein kinase C activity in human retinal pigment epithelial cells.
Experimental eye research 1998;67(1):45-52.
1998: MT Lin; David R Hinton; Beatriz Parra; Stephen A Stohlman; Roel C van der Veen
The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis.
Virology 1998;245(2):270-80.
1998: Stephen A Stohlman; Cornelia C Bergmann; MT Lin; Daniel J Cua; David R Hinton
CTL effector function within the central nervous system requires CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2896-904.
1998: T Sakamoto; Christine Spee; Z Scuric; Erlinda M Gordon; David R Hinton; W F Anderson; Stephen J Ryan
Ability of retroviral transduction to modify the angiogenic characteristics of RPE cells.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(3):220-9.
1998: X Zhang; David R Hinton; S Park; Beatriz Parra; C L Liao; Michael M C Lai; Stephen A Stohlman
Expression of hemagglutinin/esterase by a mouse hepatitis virus coronavirus defective-interfering RNA alters viral pathogenesis.
Virology 1998;242(1):170-83.
1998: David R Hinton; Shikun He; PF Lopez
Apoptosis in surgically excised choroidal neovascular membranes in age-related macular degeneration.
Archives of ophthalmology 1998;116(2):203-9.
1998: T C Chen; David R Hinton; Raphael Zidovetzki; Florence M Hofman
Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas.
Laboratory investigation; a journal of technical methods and pathology 1998;78(2):165-74.
1998: MT Lin; David R Hinton; Stephen A Stohlman
Mechanisms of viral clearance in perforin-deficient mice.
Advances in experimental medicine and biology 1998;440():431-6.
1998: Stephen A Stohlman; Cornelia C Bergmann; Daniel J Cua; MT Lin; S Ho; W Wei; David R Hinton
Apoptosis of JHMV-specific CTL in the CNS in the absence of CD4+ T cells.
Advances in experimental medicine and biology 1998;440():425-30.
1998: Ilan Shimon; David R Hinton; M H Weiss; Shlomo Melmed
Prolactinomas express human heparin-binding secretory transforming gene (hst) protein product: marker of tumour invasiveness.
Clinical endocrinology 1998;48(1):23-9.
1997: H Kimura; M S Harris; Taiji Sakamoto; Rayudu Gopalakrishna; Usha Gundimeda; Jing Z Cui; Christine Spee; David R Hinton; Stephen J Ryan
Hypericin inhibits choroidal endothelial cell proliferation and cord formation in vitro.
Current eye research 1997;16(10):967-72.
1997: D S Chen; Nian-Ling Zhu; Gene Hung; MJ Skotzko; David R Hinton; Vernon T Tolo; Frederick L Hall; W French Anderson; Erlinda M Gordon
Retroviral vector-mediated transfer of an antisense cyclin G1 construct inhibits osteosarcoma tumor growth in nude mice.
Human gene therapy 1997;8(14):1667-74.
1997: X Zhang; David R Hinton; Daniel J Cua; Stephen A Stohlman; Michael M C Lai
Expression of interferon-gamma by a coronavirus defective-interfering RNA vector and its effect on viral replication, spread, and pathogenicity.
Virology 1997;233(2):327-38.
1997: Beatriz Parra; David R Hinton; MT Lin; Daniel J Cua; Stephen A Stohlman
Kinetics of cytokine mRNA expression in the central nervous system following lethal and nonlethal coronavirus-induced acute encephalomyelitis.
Virology 1997;233(2):260-70.
1997: J A Cardillo; J Timothy Stout; L LaBree; S P Azen; L Omphroy; Jing Z Cui; H Kimura; David R Hinton; Stephen J Ryan
Post-traumatic proliferative vitreoretinopathy. The epidemiologic profile, onset, risk factors, and visual outcome.
Ophthalmology 1997;104(7):1166-73.
1997: C A Schubert; H Kimura; Christine Spee; David R Hinton; Erlinda M Gordon; W F Anderson; Stephen J Ryan
Retrovirus-mediated transfer of the suicide gene into retinal pigment epithelial cells in vitro.
Current eye research 1997;16(7):656-62.
1997: Roel C van der Veen; David R Hinton; F Incardonna; Florence M Hofman
Extensive peroxynitrite activity during progressive stages of central nervous system inflammation.
Journal of neuroimmunology 1997;77(1):1-7.
1997: Stephen A Stohlman; M Lin; Beatriz Parra; Cornelia C Bergmann; David R Hinton
Immune regulation of coronavirus-induced demyelinating encephalomyelitis.
Journal of neurovirology 1997;3 Suppl 1():S56-7.
1997: T C Chen; David R Hinton; B D Sippy; Florence M Hofman
Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas.
Journal of neuropathology and experimental neurology 1997;56(5):541-50.
1997: T C Chen; David R Hinton; V W Yong; Florence M Hofman
TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells.
Journal of neuroimmunology 1997;73(1-2):155-61.
1997: J S Yoo; Taiji Sakamoto; Christine Spee; H Kimura; M S Harris; David R Hinton; EunDuck P Kay; Stephen J Ryan
cis-Hydroxyproline inhibits proliferation, collagen synthesis, attachment, and migration of cultured bovine retinal pigment epithelial cells.
Investigative ophthalmology & visual science 1997;38(2):520-8.
1997: T Murata; H Kimura; T Sakamoto; R Osusky; Christine Spee; T J Stout; David R Hinton; Stephen J Ryan
Ocular gene therapy: experimental studies and clinical possibilities.
Ophthalmic research 1997;29(5):242-51.
1997: David R Hinton; R K Polk; Klaus D Linse; Martin H Weiss; K Kovacs; Judy A Garner
Characterization of spherical amyloid protein from a prolactin-producing pituitary adenoma.
Acta neuropathologica 1997;93(1):43-9.
1997: MT Lin; Stephen A Stohlman; David R Hinton
Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.
Journal of virology 1997;71(1):383-91.
1996: B D Sippy; Florence M Hofman; A D Wright; S He; Stephen J Ryan; David R Hinton
Soluble tumor necrosis factor receptors are present in human vitreous and shed by retinal pigment epithelial cells.
Experimental eye research 1996;63(3):311-7.
1996: H B Hamilton; David R Hinton; Ronald E Law; Rayudu Gopalakrishna; Y Z Su; Z H Chen; Martin H Weiss; W T Couldwell
Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application.
Journal of neurosurgery 1996;85(2):329-34.
1996: W Zhang; L Anker; Ronald E Law; David R Hinton; Rayudu Gopalakrishna; Q Pu; Usha Gundimeda; Martin H Weiss; W T Couldwell
Enhancement of radiosensitivity in human malignant glioma cells by hypericin in vitro.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(5):843-6.
1996: H Kimura; Taiji Sakamoto; J A Cardillo; Christine Spee; David R Hinton; Erlinda M Gordon; W French Anderson; Stephen J Ryan
Retrovirus-mediated suicide gene transduction in the vitreous cavity of the eye: feasibility in prevention of proliferative vitreoretinopathy.
Human gene therapy 1996;7(7):799-808.
1996: W T Couldwell; David R Hinton; A A Surnock; Christopher M DeGiorgio; L P Weiner; Michael L J Apuzzo; LS Masri; Ronald E Law; Martin H Weiss
Treatment of recurrent malignant gliomas with chronic oral high-dose tamoxifen.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(4):619-22.
1996: PF Lopez; B D Sippy; HM Lambert; Allen B Thach; David R Hinton
Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes.
Investigative ophthalmology & visual science 1996;37(5):855-68.
1996: W Zhang; David R Hinton; A A Surnock; W T Couldwell
Malignant glioma sensitivity to radiotherapy, high-dose tamoxifen, and hypericin: corroborating clinical response in vitro: case report.
Neurosurgery 1996;38(3):587-90; discussion 590-1.
1996: Taiji Sakamoto; David R Hinton; H Kimura; Christine Spee; Rayudu Gopalakrishna; Stephen J Ryan
Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(3):186-92.
1996: M S Harris; Taiji Sakamoto; H Kimura; S He; Christine Spee; Rayudu Gopalakrishna; Usha Gundimeda; J S Yoo; David R Hinton; Stephen J Ryan
Hypericin inhibits cell growth and induces apoptosis in retinal pigment epithelial cells: possible involvement of protein kinase C.
Current eye research 1996;15(3):255-62.
1996: B D Sippy; Florence M Hofman; A D Wright; J L Wang; Rayudu Gopalakrishna; Usha Gundimeda; S He; Stephen J Ryan; David R Hinton
Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 1996;37(4):597-606.
1996: W T Couldwell; Ronald E Law; David R Hinton; Rayudu Gopalakrishna; V W Yong; Martin H Weiss
Protein kinase C and growth regulation of pituitary adenomas.
Acta neurochirurgica. Supplement 1996;65():22-6.
1995: B D Sippy; Florence M Hofman; D Wallach; David R Hinton
Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1995;10(5):511-21.
1995: Daniel J Cua; David R Hinton; Stephen A Stohlman
Self-antigen-induced Th2 responses in experimental allergic encephalomyelitis (EAE)-resistant mice. Th2-mediated suppression of autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(8):4052-9.
1995: Taiji Sakamoto; H Kimura; Z Scuric; Christine Spee; Erlinda M Gordon; David R Hinton; W French Anderson; Stephen J Ryan
Inhibition of experimental proliferative vitreoretinopathy by retroviral vector-mediated transfer of suicide gene. Can proliferative vitreoretinopathy be a target of gene therapy?
Ophthalmology 1995;102(10):1417-24.
1995: H Kimura; Taiji Sakamoto; David R Hinton; Christine Spee; Y Ogura; Y Tabata; Y Ikada; Stephen J Ryan
A new model of subretinal neovascularization in the rabbit.
Investigative ophthalmology & visual science 1995;36(10):2110-9.
1995: Stephen A Stohlman; David R Hinton; Daniel J Cua; E Dimacali; J Sensintaffar; F M Hofman; Stanley Tahara; Q Yao
Tumor necrosis factor expression during mouse hepatitis virus-induced demyelinating encephalomyelitis.
Journal of virology 1995;69(9):5898-903.
1995: Taiji Sakamoto; H Sakamoto; David R Hinton; Christine Spee; T Ishibashi; Stephen J Ryan
In vitro studies of human choroidal endothelial cells.
Current eye research 1995;14(8):621-7.
1995: Daniel J Cua; David R Hinton; L Kirkman; Stephen A Stohlman
Macrophages regulate induction of delayed-type hypersensitivity and experimental allergic encephalomyelitis in SJL mice.
European journal of immunology 1995;25(8):2318-24.
1995: T L Murphy; Taiji Sakamoto; David R Hinton; Christine Spee; Usha Gundimeda; D Soriano; Rayudu Gopalakrishna; Stephen J Ryan
Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C.
Experimental eye research 1995;60(6):683-95.
1995: B D Sippy; Florence M Hofman; S He; R Osusky; S J Sheu; S M Walker; Stephen J Ryan; David R Hinton
SV40-immortalized and primary cultured human retinal pigment epithelial cells share similar patterns of cytokine-receptor expression and cytokine responsiveness.
Current eye research 1995;14(6):495-503.
1995: Taiji Sakamoto; T Ishibashi; H Kimura; H Yoshikawa; Christine Spee; M S Harris; David R Hinton; Stephen J Ryan
Effect of tecogalan sodium on angiogenesis in vitro by choroidal endothelial cells.
Investigative ophthalmology & visual science 1995;36(6):1076-83.
1995: J Ahmadi; G S Meyers; H D Segall; O P Sharma; David R Hinton
Lymphocytic adenohypophysitis: contrast-enhanced MR imaging in five cases.
Radiology 1995;195(1):30-4.
1995: Taiji Sakamoto; H Sakamoto; T L Murphy; Christine Spee; D Soriano; T Ishibashi; David R Hinton; Stephen J Ryan
Vessel formation by choroidal endothelial cells in vitro is modulated by retinal pigment epithelial cells.
Archives of ophthalmology 1995;113(4):512-20.
1995: W T Couldwell; Martin H Weiss; Ronald E Law; David R Hinton
Paradoxical elevation of Ki-67 labeling with protein kinase inhibition in malignant gliomas.
Journal of neurosurgery 1995;82(3):461-8.
1995: Chi-Shing Zee; T Chen; David R Hinton; M Tan; H D Segall; Michael L J Apuzzo
Magnetic resonance imaging of cystic meningiomas and its surgical implications.
Neurosurgery 1995;36(3):482-8.
1995: Taiji Sakamoto; D Soriano; J Nassaralla; T L Murphy; A Oganesian; Christine Spee; David R Hinton; Stephen J Ryan
Effect of intravitreal administration of indomethacin on experimental subretinal neovascularization in the subhuman primate.
Archives of ophthalmology 1995;113(2):222-6.
1995: Stephen A Stohlman; Q Yao; Cornelia C Bergmann; Stanley Tahara; S Kyuwa; David R Hinton
Transcription and translation of proinflammatory cytokines following JHMV infection.
Advances in experimental medicine and biology 1995;380():173-8.
1995: Taiji Sakamoto; David R Hinton; H Sakamoto; Rayudu Gopalakrishna; Stephen J Ryan; Peter J McDonnell
Thrombin induced cytoskeletal change in cultured bovine corneal endothelial cells mediated via protein kinase C pathway.
Current eye research 1995;14(1):35-45.
1994: K D Jones; W T Couldwell; David R Hinton; Y Su; S He; L Anker; Ronald E Law
Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells.
Biochemical and biophysical research communications 1994;205(3):1681-7.
1994: K Gabrielian; R Osusky; B D Sippy; Stephen J Ryan; David R Hinton
Effect of TGF-beta on interferon-gamma-induced HLA-DR expression in human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 1994;35(13):4253-9.
1994: T C Chen; David R Hinton; Lawrence Leichman; R D Atkinson; Michael L J Apuzzo; W T Couldwell
Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report.
Neurosurgery 1994;35(6):1138-42; discussion 1142-3.
1994: S A Kureshi; F M Hofman; J H Schneider; Lawrence S Chin; Michael L J Apuzzo; David R Hinton
Cytokine expression in radiation-induced delayed cerebral injury.
Neurosurgery 1994;35(5):822-9; discussion 829-30.
1994: S J Sheu; Taiji Sakamoto; R Osusky; H M Wang; T E Ogden; Stephen J Ryan; David R Hinton; Rayudu Gopalakrishna
Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1994;232(11):695-701.
1994: W T Couldwell; Rayudu Gopalakrishna; David R Hinton; S He; Martin H Weiss; Ronald E Law; Michael L J Apuzzo; R E Law
Hypericin: a potential antiglioma therapy.
Neurosurgery 1994;35(4):705-9; discussion 709-10.
1994: Florence M Hofman; M M Dohadwala; A D Wright; David R Hinton; S M Walker
Exogenous tat protein activates central nervous system-derived endothelial cells.
Journal of neuroimmunology 1994;54(1-2):19-28.
1994: J Ahmadi; David R Hinton; H D Segall; W T Couldwell
Surgical implications of magnetic resonance-enhanced dura.
Neurosurgery 1994;35(3):370-7;discussion 377.
1994: S Destian; H Tung; R Gray; David R Hinton; J Day; T Fukushima
Giant infectious intracavernous carotid artery aneurysm presenting as intractable epistaxis.
Surgical neurology 1994;41(6):472-6.
1994: Taiji Sakamoto; David R Hinton; H Sakamoto; A Oganesian; Leon Kohen; R Gopalakrishna; Stephen J Ryan
Collagen gel contraction induced by retinal pigment epithelial cells and choroidal fibroblasts involves the protein kinase C pathway.
Current eye research 1994;13(6):451-9.
1994: W T Couldwell; David R Hinton; S He; T C Chen; I Sebat; Martin H Weiss; Ronald E Law
Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines.
FEBS letters 1994;345(1):43-6.
1994: D L Robinson; S Destian; David R Hinton
Synovial sarcoma of the neck: radiographic findings with a review of the literature.
American journal of otolaryngology 1994;15(1):46-53.
1993: Lawrence S Chin; C H Rabb; David R Hinton; Michael L J Apuzzo
Hemangiopericytoma of the temporal bone presenting as a retroauricular mass.
Neurosurgery 1993;33(4):728-31; discussion 731-2.
1993: J Ahmadi; David R Hinton; H D Segall; W T Couldwell; Robert B Stanley
Dural invasion by craniofacial and calvarial neoplasms: MR imaging and histopathologic evaluation.
Radiology 1993;188(3):747-9.
1993: W T Couldwell; Martin H Weiss; Christopher M DeGiorgio; L P Weiner; David R Hinton; G R Ehresmann; Peter S Conti; Michael L J Apuzzo
Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen.
Neurosurgery 1993;32(3):485-9; discussion 489-90.
1993: J O Fleming; F I Wang; Melvin D Trousdale; David R Hinton; Stephen A Stohlman
Interaction of immune and central nervous systems: contribution of anti-viral Thy-1+ cells to demyelination induced by coronavirus JHM.
Regional immunology 1993;5(1):37-43.
1993: T C Chen; David R Hinton; Michael L J Apuzzo; F M Hofman
Differential effects of tumor necrosis factor-alpha on proliferation, cell surface antigen expression, and cytokine interactions in malignant gliomas.
Neurosurgery 1993;32(1):85-94.
1992: J Schneider; F M Hofman; M L Apuzzo; David R Hinton
Cytokines and immunoregulatory molecules in malignant glial neoplasms.
Journal of neurosurgery 1992;77(2):265-73.
1992: F I Wang; David R Hinton; Wendy Gilmore; Melvin D Trousdale; J O Fleming
Sequential infection of glial cells by the murine hepatitis virus JHM strain (MHV-4) leads to a characteristic distribution of demyelination.
Laboratory investigation; a journal of technical methods and pathology 1992;66(6):744-54.
1992: Florence M Hofman; David R Hinton
Tumor necrosis factor-alpha in the retina in acquired immune deficiency syndrome.
Investigative ophthalmology & visual science 1992;33(6):1829-35.
1992: M S Gee; K E Kliewer; David R Hinton
Nucleolar organizer regions in paragangliomas of the head and neck.
Archives of otolaryngology--head & neck surgery 1992;118(4):380-3.
1991: Lawrence S Chin; David R Hinton
The standardized assessment of argyrophilic nucleolar organizer regions in meningeal tumors.
Journal of neurosurgery 1991;74(4):590-6.
1990: A J Appley; P L Fitzgibbons; P T Chandrasoma; David R Hinton; Michael L J Apuzzo
Multiparameter flow cytometric analysis of neoplasms of the central nervous system: correlation of nuclear antigen p105 and DNA content with clinical behavior.
Neurosurgery 1990;27(1):83-96.
1990: J O Fleming; F I Wang; Melvin D Trousdale; David R Hinton; Stephen A Stohlman
Immunopathogenesis of demyelination induced by MHV-4.
Advances in experimental medicine and biology 1990;276():565-72.
1990: F M Hofman; David R Hinton
Cytokine interactions in the central nervous system.
Regional immunology 1990;3(5):268-78.