Thomas Hintze

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TOP 3
Song Su; Burleson Paul D; Passo Stanley; Messina Edward J; Levine Norman; Thompson Carl I; Belloni Francis L; Recchia Fabio A; Ojaimi Caroline; Kaley Gabor; Hintze Thomas H
Cardiac structure and function in humans: a new cardiovascular physiology laboratory.
Gupte Sachin A; Kaminski Pawel M; George Shimran; Kouznestova Lioubov; Olson Susan C; Mathew Rajamma; Hintze Thomas H; Wolin Michael S
Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction.
Zhao Gong; Serpllion Sabrina; Shryock John; Messina Eric; Xu Xiaobin; Ochoa Manuel; Belardinelli Luiz; Hintze Thomas H
Regadenoson, a novel pharmacologic stress agent for use in myocardial perfusion imaging, does not have a direct effect on the QT interval in conscious dogs.

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All Publications

2009: Song Su; Burleson Paul D; Passo Stanley; Messina Edward J; Levine Norman; Thompson Carl I; Belloni Francis L; Recchia Fabio A; Ojaimi Caroline; Kaley Gabor; Hintze Thomas H
Cardiac structure and function in humans: a new cardiovascular physiology laboratory.
Advances in physiology education 2009;33(3):221-9.
2009: Gupte Sachin A; Kaminski Pawel M; George Shimran; Kouznestova Lioubov; Olson Susan C; Mathew Rajamma; Hintze Thomas H; Wolin Michael S
Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction.
American journal of physiology. Heart and circulatory physiology 2009;296(4):H1048-57.
2008: Zhao Gong; Serpllion Sabrina; Shryock John; Messina Eric; Xu Xiaobin; Ochoa Manuel; Belardinelli Luiz; Hintze Thomas H
Regadenoson, a novel pharmacologic stress agent for use in myocardial perfusion imaging, does not have a direct effect on the QT interval in conscious dogs.
Journal of cardiovascular pharmacology 2008;52(5):467-73.
2008: Williams Jeffrey G; Ojaimi Caroline; Qanud Khaled; Zhang Suhua; Xu Xiaobin; Recchia Fabio A; Hintze Thomas H
Coronary nitric oxide production controls cardiac substrate metabolism during pregnancy in the dog.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2516-23.
2007: Csiszar Anna; Labinskyy Nazar; Zhao Xiangmin; Hu Furong; Serpillon Sabrina; Huang Zhishan; Ballabh Praveen; Levy Richard J; Hintze Thomas H; Wolin Michael S; Austad Steven N; Podlutsky Andrej; Ungvari Zoltan
Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity.
Aging cell 2007;6(6):783-97.
2007: Ojaimi Caroline; Qanud Khaled; Hintze Thomas H; Recchia Fabio A
Altered expression of a limited number of genes contributes to cardiac decompensation during chronic ventricular tachypacing in dogs.
Physiological genomics 2007;29(1):76-83.
2007: Suematsu Nobuhiro; Ojaimi Caroline; Kinugawa Shintaro; Wang Zipping; Xu Xiaobin; Koller Akos; Recchia Fabio A; Hintze Thomas H
Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress.
Circulation 2007;115(2):255-62.
2006: Zhao Gong; Messina Eric; Xu Xiaobin; Ochoa Manuel; Serpillon Sobrina; Shryock John; Belardinelli Luiz; Hintze Thomas H
Ranolazine, a novel anti-anginal agent, does not alter isosorbide dinitrate- or sildenafil-induced changes in blood pressure in conscious dogs.
European journal of pharmacology 2006;541(3):171-6.
2006: Zhang Xiao-Ping; Hintze Thomas H
cAMP signal transduction induces eNOS activation by promoting PKB phosphorylation.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2376-84.
2006: Ferrarini Matteo; Arsic Nikola; Recchia Fabio A; Zentilin Lorena; Zacchigna Serena; Xu Xiaobin; Linke Axel; Giacca Mauro; Hintze Thomas H
Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs.
Circulation research 2006;98(7):954-61.
2006: d'Agostino Chiara; Labinskyy Volodymyr; Lionetti Vincenzo; Chandler Margaret P; Lei Biao; Matsuo Ken; Bellomo Michelle; Xu Xiaobin; Hintze Thomas H; Stanley William C; Recchia Fabio A
Altered cardiac metabolic phenotype after prolonged inhibition of NO synthesis in chronically instrumented dogs.
American journal of physiology. Heart and circulatory physiology 2006;290(4):H1721-6.
2005: Ojaimi Caroline; Li Wei; Kinugawa Shintaro; Post Heiner; Csiszar Anna; Pacher Pal; Kaley Gabor; Hintze Thomas H
Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.
American journal of physiology. Heart and circulatory physiology 2005;289(4):H1399-407.
2005: Kinugawa Shintaro; Zhang Juhua; Messina Eric; Walsh Erin; Huang Harer; Kaminski Pawel M; Wolin Michael S; Hintze Thomas H
gp91phox-containing NAD(P)H oxidase mediates attenuation of nitric oxide-dependent control of myocardial oxygen consumption by ANG II.
American journal of physiology. Heart and circulatory physiology 2005;289(2):H862-7.
2005: Lionetti Vincenzo; Linke Axel; Chandler Margaret P; Young Martin E; Penn Marc S; Gupte Sachin; d'Agostino Chiara; Hintze Thomas H; Stanley William C; Recchia Fabio A
Carnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure.
Cardiovascular research 2005;66(3):454-61.
2005: Lei Biao; Matsuo Ken; Labinskyy Volodymyr; Sharma Naveen; Chandler Margaret P; Ahn Anna; Hintze Thomas H; Stanley William C; Recchia Fabio A
Exogenous nitric oxide reduces glucose transporters translocation and lactate production in ischemic myocardium in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(19):6966-71.
2005: Yan Changdong; Huang An; Wu Zhiping; Kaminski Pawel M; Wolin Michael S; Hintze Thomas H; Kaley Gabor; Sun Dong
Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice.
American journal of physiology. Heart and circulatory physiology 2005;288(5):H2225-31.
2005: Becker Justin S; Adler Alexandra; Schneeberger Aaron; Huang Harer; Wang Zipping; Walsh Erin; Koller Akos; Hintze Thomas H
Hyperhomocysteinemia, a cardiac metabolic disease: role of nitric oxide and the p22phox subunit of NADPH oxidase.
Circulation 2005;111(16):2112-8.
2005: Kinugawa Shintaro; Wang Ziping; Kaminski Pawel M; Wolin Michael S; Edwards John G; Kaley Gabor; Hintze Thomas H
Limited exercise capacity in heterozygous manganese superoxide dismutase gene-knockout mice: roles of superoxide anion and nitric oxide.
Circulation 2005;111(12):1480-6.
2005: Kinugawa Shintaro; Huang Harer; Wang Ziping; Kaminski Pawel M; Wolin Michael S; Hintze Thomas H
A defect of neuronal nitric oxide synthase increases xanthine oxidase-derived superoxide anion and attenuates the control of myocardial oxygen consumption by nitric oxide derived from endothelial nitric oxide synthase.
Circulation research 2005;96(3):355-62.
2004: Walsh E K; Huang H; Wang Z; Williams J; de Crom R; van Haperen R; Thompson C I; Lefer D J; Hintze T H
Control of myocardial oxygen consumption in transgenic mice overexpressing vascular eNOS.
American journal of physiology. Heart and circulatory physiology 2004;287(5):H2115-21.
2004: Li Wei; Mital Seema; Ojaimi Caroline; Csiszar Anna; Kaley Gabor; Hintze Thomas H
Premature death and age-related cardiac dysfunction in male eNOS-knockout mice.
Journal of molecular and cellular cardiology 2004;37(3):671-80.
2004: Adler Alexandra; Huang Harer; Wang Zipping; Conetta Joseph; Levee Ellen; Zhang Xiaoping; Hintze Thomas H
Endocardial endothelium in the avascular frog heart: role for diffusion of NO in control of cardiac O2 consumption.
American journal of physiology. Heart and circulatory physiology 2004;287(1):H14-21.
2004: Lei Biao; Lionetti Vincenzo; Young Martin E; Chandler Margaret P; d'Agostino Chiara; Kang Elaine; Altarejos Martin; Matsuo Ken; Hintze Thomas H; Stanley William C; Recchia Fabio A
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure.
Journal of molecular and cellular cardiology 2004;36(4):567-76.
2004: Mital Seema; Loke Kit E; Chen Jonathan M; Mosca Ralph S; Quaegebeur Jan M; Addonizio Linda J; Hintze Thomas H
Mitochondrial respiratory abnormalities in patients with end-stage congenital heart disease.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2004;23(1):72-9.
2004: Li Wei; Jue Thomas; Edwards John; Wang Xipping; Hintze Thomas H
Changes in NO bioavailability regulate cardiac O2 consumption: control by intramitochondrial SOD2 and intracellular myoglobin.
American journal of physiology. Heart and circulatory physiology 2004;286(1):H47-54.
2003: Kinugawa Shintaro; Post Heiner; Kaminski Pawel M; Zhang Xiaoping; Xu Xiaobin; Huang Harer; Recchia Fabio A; Ochoa Manuel; Wolin Michael S; Kaley Gabor; Hintze Thomas H
Coronary microvascular endothelial stunning after acute pressure overload in the conscious dog is caused by oxidant processes: the role of angiotensin II type 1 receptor and NAD(P)H oxidase.
Circulation 2003;108(23):2934-40.
2003: Trochu Jean-Noel; Mital Seema; Zhang Xiao ping; Xu Xiaobin; Ochoa Manuel; Liao James K; Recchia Fabio A; Hintze Thomas H
Preservation of NO production by statins in the treatment of heart failure.
Cardiovascular research 2003;60(2):250-8.
2003: Zhao Gong; Linke Axel; Xu Xiaobin; Ochoa Manuel; Belloni Francis; Belardinelli Luiz; Hintze Thomas H
Comparative profile of vasodilation by CVT-3146, a novel A2A receptor agonist, and adenosine in conscious dogs.
The Journal of pharmacology and experimental therapeutics 2003;307(1):182-9.
2003: Post Heiner; d'Agostino Chiara; Lionetti Vincenzo; Castellari Michele; Kang Elaine Y; Altarejos Martin; Xu Xiaobin; Hintze Thomas H; Recchia Fabio A
Reduced left ventricular compliance and mechanical efficiency after prolonged inhibition of NO synthesis in conscious dogs.
The Journal of physiology 2003;552(Pt 1):233-9.
2003: Post Heiner; Kajstura Jan; Lei Biao; Sessa William C; Byrne Barry; Anversa Piero; Hintze Thomas H; Recchia Fabio A
Adeno-associated virus mediated gene delivery into coronary microvessels of chronically instrumented dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(4):1688-94.
2003: Adler Alexandra; Messina Eric; Sherman Ben; Wang Zipping; Huang Harer; Linke Axel; Hintze Thomas H
NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1015-22.
2003: Linke Axel; Zhao Gong; Recchia Fabio A; Williams Jeffrey; Xu Xiaobin; Hintze Thomas H
Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1007-14.
2003: Linke Axel; Recchia Fabio; Zhang Xiaoping; Hintze Thomas H
Acute and chronic endothelial dysfunction: implications for the development of heart failure.
Heart failure reviews 2003;8(1):87-97.
2003: Trochu Jean-Noël; Zhao Gong; Post Heiner; Xu Xiaobin; Belardinelli Luiz; Belloni Francis L; Hintze Thomas H
Selective A2A adenosine receptor agonist as a coronary vasodilator in conscious dogs: potential for use in myocardial perfusion imaging.
Journal of cardiovascular pharmacology 2003;41(1):132-9.
2002: Hintze Thomas H; Shesely Edward G
Is a mouse like any other mouse?
Journal of molecular and cellular cardiology 2002;34(10):1283-6.
2002: Linke Axel; Li Wei; Huang Harer; Wang Ziping; Hintze Thomas H
Role of cardiac eNOS expression during pregnancy in the coupling of myocardial oxygen consumption to cardiac work.
American journal of physiology. Heart and circulatory physiology 2002;283(3):H1208-14.
2002: Zhang Xiao-Ping; Tada Hideo; Wang Ziping; Hintze Thomas H
cAMP signal transduction, a potential compensatory pathway for coronary endothelial NO production after heart failure.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1273-8.
2002: Osorio Juan Carlos; Stanley William C; Linke Axel; Castellari Michele; Diep Quy N; Panchal Ashish R; Hintze Thomas H; Lopaschuk Gary D; Recchia Fabio A
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure.
Circulation 2002;106(5):606-12.
2002: Sun Dong; Huang An; Mital Seema; Kichuk Maryanne R; Marboe Charles C; Addonizio Linda J; Michler Robert E; Koller Akos; Hintze Thomas H; Kaley Gabor
Norepinephrine elicits beta2-receptor-mediated dilation of isolated human coronary arterioles.
Circulation 2002;106(5):550-5.
2002: Mital Seema; Barbone Alessandro; Addonizio Linda J; Quaegebeur Jan M; Mosca Ralph J; Oz Mehmet C; Hintze Thomas H
Endogenous endothelium-derived nitric oxide inhibits myocardial caspase activity: implications for treatment of end-stage heart failure.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2002;21(5):576-85.
2002: Zhang Xiao-Ping; Loke Kit Ee; Mital Seema; Chahwala Suresh; Hintze Thomas H
Paradoxical release of nitric oxide by an L-type calcium channel antagonist, the R+ enantiomer of amlodipine.
Journal of cardiovascular pharmacology 2002;39(2):208-14.
2002: Recchia Fabio A; Osorio Juan Carlos; Chandler Margaret P; Xu Xiaobin; Panchal Ashish R; Lopaschuk Gary D; Hintze Thomas H; Stanley William C
Reduced synthesis of NO causes marked alterations in myocardial substrate metabolism in conscious dogs.
American journal of physiology. Endocrinology and metabolism 2002;282(1):E197-206.
2001: Hintze T H
Prologue: Nitric oxide--hormones, metabolism, and function.
American journal of physiology. Heart and circulatory physiology 2001;281(6):H2253-5.
2001: Adler S; Huang H; Trochu J N; Xu X; Gupta S; Hintze T H
Simvastatin reverses impaired regulation of renal oxygen consumption in congestive heart failure.
American journal of physiology. Renal physiology 2001;281(5):F802-9.
2001: Cesselli D; Jakoniuk I; Barlucchi L; Beltrami A P; Hintze T H; Nadal-Ginard B; Kajstura J; Leri A; Anversa P
Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy.
Circulation research 2001;89(3):279-86.
2001: Leri A; Barlucchi L; Limana F; Deptala A; Darzynkiewicz Z; Hintze T H; Kajstura J; Nadal-Ginard B; Anversa P
Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8626-31.
2001: Zhang X; Hintze T H
cAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(5):797-803.
2001: Adler S; Huang H; Loke K E; Xu X; Tada H; Laumas A; Hintze T H
Endothelial nitric oxide synthase plays an essential role in regulation of renal oxygen consumption by NO.
American journal of physiology. Renal physiology 2001;280(5):F838-43.
2001: Adler S; Huang H; Loke K; Xu X; Laumas A; Hintze T H
Modulation of renal oxygen consumption by nitric oxide is impaired after development of congestive heart failure in dogs.
Journal of cardiovascular pharmacology 2001;37(3):301-9.
2001: Barlucchi L; Leri A; Dostal D E; Fiordaliso F; Tada H; Hintze T H; Kajstura J; Nadal-Ginard B; Anversa P
Canine ventricular myocytes possess a renin-angiotensin system that is upregulated with heart failure.
Circulation research 2001;88(3):298-304.
2001: Osorio J C; Xu X; Vogel T; Ochoa M; Laycock S; Hintze T H
Plasma nitrate accumulation during the development of pacing-induced dilated cardiac myopathy in conscious dogs is due to renal impairment.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2001;5(1):7-17.
2001: Loke K E; Messina E J; Shesely E G; Kaley G; Hintze T H
Potential role of eNOS in the therapeutic control of myocardial oxygen consumption by ACE inhibitors and amlodipine.
Cardiovascular research 2001;49(1):86-93.
2000: Loke K E; Messina E J; Mital S; Hintze T H
Impaired nitric oxide modulation of myocardial oxygen consumption in genetically cardiomyopathic hamsters.
Journal of molecular and cellular cardiology 2000;32(12):2299-306.
2000: Trochu J N; Bouhour J B; Kaley G; Hintze T H
Role of endothelium-derived nitric oxide in the regulation of cardiac oxygen metabolism: implications in health and disease.
Circulation research 2000;87(12):1108-17.
2000: Mital S; Zhang X; Zhao G; Bernstein R D; Smith C J; Fulton D L; Sessa W C; Liao J K; Hintze T H
Simvastatin upregulates coronary vascular endothelial nitric oxide production in conscious dogs.
American journal of physiology. Heart and circulatory physiology 2000;279(6):H2649-57.
2000: Mital S; Loke K E; Addonizio L J; Oz M C; Hintze T H
Left ventricular assist device implantation augments nitric oxide dependent control of mitochondrial respiration in failing human hearts.
Journal of the American College of Cardiology 2000;36(6):1897-902.
2000: Mital S; Magneson A; Loke K E; Liao J; Forfia P R; Hintze T H
Simvastatin acts synergistically with ACE inhibitors or amlodipine to decrease oxygen consumption in rat hearts.
Journal of cardiovascular pharmacology 2000;36(2):248-54.
2000: Recchia F A; Vogel T R; Hintze T H
NO metabolites accumulate in erythrocytes in proportion to carbon dioxide and bicarbonate concentration.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H852-6.
2000: Zhao G; Zhang X; Xu X; Wolin M S; Hintze T H
Depressed modulation of oxygen consumption by endogenous nitric oxide in cardiac muscle from diabetic dogs.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H520-7.
2000: Pittis M; Zhang X; Loke K E; Mital S; Kaley G; Hintze T H
Canine coronary microvessel NO production regulates oxygen consumption in ecNOS knockout mouse heart.
Journal of molecular and cellular cardiology 2000;32(7):1141-6.
2000: Shen W; Xu X; Ochoa M; Zhao G; Bernstein R D; Forfia P; Hintze T H
Endogenous nitric oxide in the control of skeletal muscle oxygen extraction during exercise.
Acta physiologica Scandinavica 2000;168(4):675-86.
2000: Tada H; Thompson C I; Recchia F A; Loke K E; Ochoa M; Smith C J; Shesely E G; Kaley G; Hintze T H
Myocardial glucose uptake is regulated by nitric oxide via endothelial nitric oxide synthase in Langendorff mouse heart.
Circulation research 2000;86(3):270-4.
2000: Zhang X; Xu X; Nasjletti A; Hintze T H
Amlodipine enhances NO production induced by an ACE inhibitor through a kinin-mediated mechanism in canine coronary microvessels.
Journal of cardiovascular pharmacology 2000;35(2):195-202.
2000: Sun D; Huang A; Zhao G; Bernstein R; Forfia P; Xu X; Koller A; Kaley G; Hintze T H
Reduced NO-dependent arteriolar dilation during the development of cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2000;278(2):H461-8.
2000: Recchia F A; Bernstein R D; Sehgal P B; Ferreri N R; Hintze T H
Cytokines are not a requisite part of the pathophysiology leading to cardiac decompensation.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 2000;223(1):47-52.
2000: Loke K E; Forfia P R; Recchia F A; Xu X; Osorio J C; Ochoa M; Gawryl M; Hintze T H
Bovine polymerized hemoglobin increases cardiac oxygen consumption and alters myocardial substrate metabolism in conscious dogs: role of nitric oxide.
Journal of cardiovascular pharmacology 2000;35(1):84-92.
1999: Recchia F A; McConnell P I; Loke K E; Xu X; Ochoa M; Hintze T H
Nitric oxide controls cardiac substrate utilization in the conscious dog.
Cardiovascular research 1999;44(2):325-32.
1999: Loke K E; Curran C M; Messina E J; Laycock S K; Shesely E G; Carretero O A; Hintze T H
Role of nitric oxide in the control of cardiac oxygen consumption in B(2)-kinin receptor knockout mice.
Hypertension 1999;34(4 Pt 1):563-7.
1999: Loke K E; Laycock S K; Mital S; Wolin M S; Bernstein R; Oz M; Addonizio L; Kaley G; Hintze T H
Nitric oxide modulates mitochondrial respiration in failing human heart.
Circulation 1999;100(12):1291-7.
1999: Zhang X; Kichuk M R; Mital S; Oz M; Michler R; Nasjletti A; Kaley G; Hintze T H
Amlodipine promotes kinin-mediated nitric oxide production in coronary microvessels of failing human hearts.
The American journal of cardiology 1999;84(4A):27L-33L.
1999: Zhao G; Bernstein R D; Hintze T H
Nitric oxide and oxygen utilization: exercise, heart failure and diabetes.
Coronary artery disease 1999;10(5):315-20.
1999: Zhao G; Zhang X; Smith C J; Xu X; Ochoa M; Greenhouse D; Vogel T; Curran C; Hintze T H
Reduced coronary NO production in conscious dogs after the development of alloxan-induced diabetes.
The American journal of physiology 1999;277(1 Pt 2):H268-78.
1999: Mital S; Loke K E; Slater J P; Addonizio L; Gersony W M; Hintze T H
Synergy of amlodipine and angiotensin-converting enzyme inhibitors in regulating myocardial oxygen consumption in normal canine and failing human hearts.
The American journal of cardiology 1999;83(12A):92H-98H.
1999: Forfia P R; Zhang X; Knight D R; Smith A H; Doe C P; Wolfgang E A; Flynn D M; Wolin M S; Hintze T H
NO modulates myocardial O2 consumption in the nonhuman primate: an additional mechanism of action of amlodipine.
The American journal of physiology 1999;276(6 Pt 2):H2069-75.
1999: Loke K E; McConnell P I; Tuzman J M; Shesely E G; Smith C J; Stackpole C J; Thompson C I; Kaley G; Wolin M S; Hintze T H
Endogenous endothelial nitric oxide synthase-derived nitric oxide is a physiological regulator of myocardial oxygen consumption.
Circulation research 1999;84(7):840-5.
1999: Zhang X; Recchia F A; Bernstein R; Xu X; Nasjletti A; Hintze T H
Kinin-mediated coronary nitric oxide production contributes to the therapeutic action of angiotensin-converting enzyme and neutral endopeptidase inhibitors and amlodipine in the treatment in heart failure.
The Journal of pharmacology and experimental therapeutics 1999;288(2):742-51.
1999: Wolin M S; Xie Y W; Hintze T H
Nitric oxide as a regulator of tissue oxygen consumption.
Current opinion in nephrology and hypertension 1999;8(1):97-103.
1999: Forfia P R; Hintze T H; Wolin M S; Kaley G
Role of nitric oxide in the control of mitochondrial function.
Advances in experimental medicine and biology 1999;471():381-8.
1998: Recchia F A; McConnell P I; Bernstein R D; Vogel T R; Xu X; Hintze T H
Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog.
Circulation research 1998;83(10):969-79.
1998: Laycock S K; Vogel T; Forfia P R; Tuzman J; Xu X; Ochoa M; Thompson C I; Nasjletti A; Hintze T H
Role of nitric oxide in the control of renal oxygen consumption and the regulation of chemical work in the kidney.
Circulation research 1998;82(12):1263-71.
1998: Zhang X; Nasjletti A; Xu X; Hintze T H
Neutral endopeptidase and angiotensin-converting enzyme inhibitors increase nitric oxide production in isolated canine coronary microvessels by a kinin-dependent mechanism.
Journal of cardiovascular pharmacology 1998;31(4):623-9.
1998: Stewart J M; Xu X; Ochoa M; Hintze T H
Exercise reduces epicardial coronary artery wall stiffness: roles of cGMP and cAMP.
Medicine and science in sports and exercise 1998;30(2):220-8.
1998: Zhang X; Hintze T H
Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent.
Circulation 1998;97(6):576-80.
1998: Sakakibara T; Hintze T H; Nasjletti A
Determinants of kinin release in isolated rat hindquarters.
The American journal of physiology 1998;274(1 Pt 2):R120-5.
1998: Forfia P R; Zhang X; Ochoa F; Ochoa M; Xu X; Bernstein R; Sehgal P B; Ferreri N R; Hintze T H
Relationship between plasma NOx and cardiac and vascular dysfunction after LPS injection in anesthetized dogs.
The American journal of physiology 1998;274(1 Pt 2):H193-201.
1998: Leri A; Liu Y; Malhotra A; Li Q; Stiegler P; Claudio P P; Giordano A; Kajstura J; Hintze T H; Anversa P
Pacing-induced heart failure in dogs enhances the expression of p53 and p53-dependent genes in ventricular myocytes.
Circulation 1998;97(2):194-203.
1997: Zhang X; Scicli G A; Xu X; Nasjletti A; Hintze T H
Role of endothelial kinins in control of coronary nitric oxide production.
Hypertension 1997;30(5):1105-11.
1997: Bernstein R D; Zhang X; Zhao G; Forfia P; Tuzman J; Ochoa F; Ochoa M; Vogel T; Hintze T H
Mechanisms of nitrate accumulation in plasma during pacing-induced heart failure in conscious dogs.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(5):386-96.
1997: Shen W; Wolin M S; Hintze T H
Defective endogenous nitric oxide-mediated modulation of cellular respiration in canine skeletal muscle after the development of heart failure.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1997;16(10):1026-34.
1997: Wolin M S; Hintze T H; Shen W; Mohazzab-H K M; Xie Y W
Involvement of reactive oxygen and nitrogen species in signalling mechanisms that control tissue respiration in muscle.
Biochemical Society transactions 1997;25(3):934-9.
1997: Kichuk M R; Zhang X; Oz M; Michler R; Kaley G; Nasjletti A; Hintze T H
Angiotensin-converting enzyme inhibitors promote nitric oxide production in coronary microvessels from failing explanted human hearts.
The American journal of cardiology 1997;80(3A):137A-142A.
1997: Zhao G; Zhang X; Xu X; Ochoa M; Hintze T H
Short-term exercise training enhances reflex cholinergic nitric oxide-dependent coronary vasodilation in conscious dogs.
Circulation research 1997;80(6):868-76.
1997: Zhang X; Xie Y W; Nasjletti A; Xu X; Wolin M S; Hintze T H
ACE inhibitors promote nitric oxide accumulation to modulate myocardial oxygen consumption.
Circulation 1997;95(1):176-82.
1996: Zhao G; Xu X; Ochoa M; Shen W; Hintze T H
Interaction between prostacyclin and nitric oxide in the reflex control of the coronary circulation in conscious dogs.
Cardiovascular research 1996;32(5):940-8.
1996: Bernstein R D; Ochoa F Y; Xu X; Forfia P; Shen W; Thompson C I; Hintze T H
Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise.
Circulation research 1996;79(4):840-8.
1996: Xie Y W; Shen W; Zhao G; Xu X; Wolin M S; Hintze T H
Role of endothelium-derived nitric oxide in the modulation of canine myocardial mitochondrial respiration in vitro. Implications for the development of heart failure.
Circulation research 1996;79(3):381-7.
1996: Kichuk M R; Seyedi N; Zhang X; Marboe C C; Michler R E; Addonizio L J; Kaley G; Nasjletti A; Hintze T H
Regulation of nitric oxide production in human coronary microvessels and the contribution of local kinin formation.
Circulation 1996;94(1):44-51.
1996: Shen W; Xu X; Ochoa M; Zeballos G A; Stewart J M; Hintze T H
Contribution of the ventricles and the atrial appendages to the elevation of plasma atrial natriuretic factor (ANF) during pacing-induced heart failure in conscious dogs.
Basic research in cardiology 1996;91(4):319-28.
1996: Zhao G; Hintze T H; Kaley G
Neural regulation of coronary vascular resistance: role of nitric oxide in reflex cholinergic coronary vasodilation in normal and pathophysiologic states.
EXS 1996;76():1-19.
1995: Shen W; Hintze T H; Wolin M S
Nitric oxide. An important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption.
Circulation 1995;92(12):3505-12.
1995: Shen W; Zhang X; Zhao G; Wolin M S; Sessa W; Hintze T H
Nitric oxide production and NO synthase gene expression contribute to vascular regulation during exercise.
Medicine and science in sports and exercise 1995;27(8):1125-34.
1995: Seyedi N; Xu X; Nasjletti A; Hintze T H
Coronary kinin generation mediates nitric oxide release after angiotensin receptor stimulation.
Hypertension 1995;26(1):164-70.
1995: Zeballos G A; Bernstein R D; Thompson C I; Forfia P R; Seyedi N; Shen W; Kaminiski P M; Wolin M S; Hintze T H
Pharmacodynamics of plasma nitrate/nitrite as an indication of nitric oxide formation in conscious dogs.
Circulation 1995;91(12):2982-8.
1995: Zhao G; Shen W; Xu X; Ochoa M; Bernstein R; Hintze T H
Selective impairment of vagally mediated, nitric oxide-dependent coronary vasodilation in conscious dogs after pacing-induced heart failure.
Circulation 1995;91(10):2655-63.
1994: Stewart J M; Wang J; Hintze T H
Role of EDRF in the regulation of shear rate in large coronary arteries in conscious dogs.
Journal of molecular and cellular cardiology 1994;26(12):1625-33.
1994: Shen W; Xu X; Ochoa M; Zhao G; Wolin M S; Hintze T H
Role of nitric oxide in the regulation of oxygen consumption in conscious dogs.
Circulation research 1994;75(6):1086-95.
1994: Shen W; Ochoa M; Xu X; Wang J; Hintze T H
Role of EDRF/NO in parasympathetic coronary vasodilation following carotid chemoreflex activation in conscious dogs.
The American journal of physiology 1994;267(2 Pt 2):H605-13.
1994: Shen W; Lundborg M; Wang J; Stewart J M; Xu X; Ochoa M; Hintze T H
Role of EDRF in the regulation of regional blood flow and vascular resistance at rest and during exercise in conscious dogs.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;77(1):165-72.
1994: Wang J; Seyedi N; Xu X B; Wolin M S; Hintze T H
Defective endothelium-mediated control of coronary circulation in conscious dogs after heart failure.
The American journal of physiology 1994;266(2 Pt 2):H670-80.
1994: Sessa W C; Pritchard K; Seyedi N; Wang J; Hintze T H
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression.
Circulation research 1994;74(2):349-53.
1993: Wang J; Wolin M S; Hintze T H
Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs.
Circulation research 1993;73(5):829-38.
1993: Stewart J M; Wang J; Zeballos G A; Ochoa M; Schustek M; Hintze T H
Role of tachycardia and V wave wall stress in the release of ANF during volume loading.
The American journal of physiology 1993;264(1 Pt 2):H217-23.
1993: Wang J; Zhao G; Shen W; Ochoa M; Moore D; Hubbard J W; Hintze T H
Effects of an orally active NO-releasing agent, CAS 936, and its active metabolite, 3754, on cardiac and coronary dynamics in normal conscious dogs and after pacing-induced heart failure.
Journal of cardiovascular pharmacology 1993;22 Suppl 7():S51-8.
1992: Stewart J M; Dean R; Brown M; Diasparra D; Zeballos G A; Schustek M; Gewitz M H; Thompson C I; Hintze T H
Bilateral atrial appendectomy abolishes increased plasma atrial natriuretic peptide release and blunts sodium and water excretion during volume loading in conscious dogs.
Circulation research 1992;70(4):724-32.
1992: Belloni F L; Wang J; Hintze T H
Adenosine causes bradycardia in pacing-induced cardiac failure.
Circulation 1992;85(3):1118-24.
1992: Stewart J M; Patel M B; Wang J; Ochoa M; Gewitz M; Loud A V; Anversa P; Hintze T H
Chronic elevation of norepinephrine in conscious dogs produces hypertrophy with no loss of LV reserve.
The American journal of physiology 1992;262(2 Pt 2):H331-9.
1991: Wang J; Zeballos G A; Kaley G; Hintze T H
Dilation and constriction of large coronary arteries in conscious dogs by endothelin.
The American journal of physiology 1991;261(5 Pt 2):H1379-86.
1991: Patel M B; Stewart J M; Loud A V; Anversa P; Wang J; Fiegel L; Hintze T H
Altered function and structure of the heart in dogs with chronic elevation in plasma norepinephrine.
Circulation 1991;84(5):2091-100.
1991: Belloni F L; Hintze T H
Glibenclamide attenuates adenosine-induced bradycardia and coronary vasodilatation.
The American journal of physiology 1991;261(3 Pt 2):H720-7.
1991: Stewart J M; O'Dea D J; Shapiro G C; Patel M B; McIntyre J T; Gewitz M H; Hoegler C T; Shapiro J T; Zeballos G A; Hintze T H
Atrial compliance determines the nature of passive atrial stretch and plasma atrial natriuretic factor in the conscious dog.
Cardiovascular research 1991;25(9):784-92.
1991: Wang J; Ochoa M; Patel M B; Zucker I H; Loud A V; Zeballos G A; Hintze T H
Carotid baroreceptor function in dogs with chronic norepinephrine infusion.
Hypertension 1991;17(6 Pt 1):745-54.
1990: Stewart J M; Wang J; Singer A; Zeballos G A; Ochoa M; Patel M B; Gewitz M H; Hintze T H
Regulation of plasma ANF after increases in afterload in conscious dogs.
The American journal of physiology 1990;259(6 Pt 2):H1736-42.
1990: Hintze T H; Wang J; Patel M; Schustek M; Ochoa M; Dean R; Chiruzzo F; Zeballos G
Dynamics of atrial peptide secretion in the coronary circulation of the conscious dog.
Circulation research 1990;67(3):609-14.
1990: Nganele D M; Hintze T H
Cardiac chemical reflex control of preload in conscious dogs.
The American journal of physiology 1990;258(4 Pt 2):H1055-63.
1990: Patel M B; Hintze T H
Atriopeptin 24 regulates myocardial function via Frank-Starling mechanism in conscious dogs.
The American journal of physiology 1990;258(1 Pt 2):H183-90.
1989: Patel M B; Loud A V; King B D; Anversa P; Sack D; Hintze T H
Global myocardial hypertrophy in conscious dogs with chronic elevation of plasma norepinephrine levels.
Journal of molecular and cellular cardiology 1989;21 Suppl 5():49-61.
1989: Hoegler C; McIntyre J; Zeballos G; Shapiro J; DeLeonardis M; Needleman P; Hintze T
Relationship between plasma atriopeptin concentration and function in the conscious primate.
The Journal of pharmacology and experimental therapeutics 1989;251(3):929-36.
1989: Belloni F L; Belardinelli L; Halperin C; Hintze T H
An unusual receptor mediates adenosine-induced SA nodal bradycardia in dogs.
The American journal of physiology 1989;256(6 Pt 2):H1553-64.
1989: Belloni F L; Brown I; Hintze T H
Mechanism of the apparent parasympathetic inhibition of adenosine induced heart rate slowing in the dog.
Cardiovascular research 1989;23(3):239-48.
1989: Hintze T H; McIntyre J J; Patel M B; Shapiro J T; DeLeonardis M; Zeballos G A; Loud A V
Atrial wall function and plasma atriopeptin during volume expansion in conscious dogs.
The American journal of physiology 1989;256(3 Pt 2):H713-9.
1988: Hintze T H
Significance of renal vasodilation after administration of atrial natriuretic factor in the conscious dog.
Hypertension 1988;12(2):143-51.
1988: Panzenbeck M J; Hintze T H; Kaley G
6-Keto-prostaglandin E1 is a potent coronary vasodilator and stimulates a vagal reflex in dogs.
The Journal of pharmacology and experimental therapeutics 1988;244(3):814-9.
1988: Nganele D M; DeLeonardis V M; Hintze T H
Celiprolol: a positive inotropic beta-adrenoceptor blocking agent in conscious dogs.
British journal of pharmacology 1988;93(3):501-8.
1987: Nganele D M; Hintze T H
Prostacyclin reduces "preload" in conscious dogs via a vagal reflex mechanism.
The American journal of physiology 1987;253(6 Pt 2):H1477-83.
1987: Nganele D M; Hintze T H
Stimulation of prostaglandin synthesis reduces preload via a vagal reflex in conscious dogs.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17A():414-7.
1985: Hintze T H; Kichuk M R; Stern H; Kaley G
Dilation of large coronary arteries in conscious dogs by prostacyclin.
Advances in prostaglandin, thromboxane, and leukotriene research 1985;13():341-4.
1985: Kaley G; Hintze T H; Panzenbeck M; Messina E J
Role of prostaglandins in microcirculatory function.
Advances in prostaglandin, thromboxane, and leukotriene research 1985;13():27-35.
1984: Hintze T H; Kaley G; Panzenbeck M J
Mechanisms of reflex bradycardia and hypotension by metabolites of arachidonic acid in the cat.
British journal of pharmacology 1984;82(1):117-25.
1981: Hintze T H; Panzenbeck M J; Messina E J; Kaley G
Prostacyclin (PGI2) lowers heart rate in the conscious dog.
Cardiovascular research 1981;15(9):538-46.

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