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Yusuke Hirasawa

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Mineri Ishizuka; Toshio Kaneda; Ikumi Koga; A Hamid A Hadi; Yusuke Hirasawa; Kazumasa Zaima; Hiroshi Morita
Vasorelaxant effects on rat aortic artery by two types of indole alkaloids, naucline and cadamine.
Yuta Nagakura; Alfarius Eko Nugroho; Abdul Rahman; Noor Cholies Zaini; Yusuke Hirasawa; Takahiro Hosoya; Idha Kusumawati; Hiroshi Morita
Sanjecumins A and B: new limonoids from Sandoricum koetjape.
Fumie Yamasaki; Naoyuki Hagane; Yusuke Hirasawa; Toshio Kaneda; Shoko Machida; Asami Nakata; Alfarius Eko Nugroho; Osamu Shirota; Tadayoshi Sugizaki; Hiroshi Morita
Haworforbins A-C, new phenolics from Haworthia cymbiformis.

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2013: Mineri Ishizuka; Toshio Kaneda; Ikumi Koga; A Hamid A Hadi; Yusuke Hirasawa; Kazumasa Zaima; Hiroshi Morita
Vasorelaxant effects on rat aortic artery by two types of indole alkaloids, naucline and cadamine.
Journal of natural medicines 2013;67(2):399-403.
2013: Yuta Nagakura; Alfarius Eko Nugroho; Abdul Rahman; Noor Cholies Zaini; Yusuke Hirasawa; Takahiro Hosoya; Idha Kusumawati; Hiroshi Morita
Sanjecumins A and B: new limonoids from Sandoricum koetjape.
Journal of natural medicines 2013;67(2):381-5.
2013: Fumie Yamasaki; Naoyuki Hagane; Yusuke Hirasawa; Toshio Kaneda; Shoko Machida; Asami Nakata; Alfarius Eko Nugroho; Osamu Shirota; Tadayoshi Sugizaki; Hiroshi Morita
Haworforbins A-C, new phenolics from Haworthia cymbiformis.
Journal of natural medicines 2013;67(1):212-6.
2013: Kazumasa Zaima; Jun Deguchi; Yusuke Hirasawa; Toshio Kaneda; Yosuke Matsuno; Hiroshi Morita
Vasorelaxant effect of FR900359 from Ardisia crenata on rat aortic artery.
Journal of natural medicines 2013;67(1):196-201.
2013: Kazumasa Zaima; Yusuke Hirasawa; Takahiro Hosoya; Intan Safinar Ismail; Nobuhide Iwasawa; Toshio Kaneda; Ikumi Koga; Nordin Hj Lajis; Hiroshi Morita
Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma.
Journal of natural medicines 2013;67(1):9-16.
2012: Hiroshi Morita; Shiori Oshimi; Aty Widyawaruyanti; Jun Deguchi; Wiwied Ekasari; Yusuke Hirasawa; Reika Mori; A Hamid A Hadi
Antiplasmodial decarboxyportentol acetate and 3,4-dehydrotheaspirone from Laumoniera bruceadelpha.
Journal of natural medicines 2012;66(3):571-5.
2012: Chin Piow Wong; Alfarius Eko Nugroho; Shirota Osamu; Misae Shimada; A Hamid A Hadi; Yusuke Hirasawa; Toshio Kaneda; Hiroshi Morita
Ceramicines J-L, new limonoids from Chisocheton ceramicus.
Journal of natural medicines 2012;66(3):566-70.
2012: Hiroko Arai; Yusuke Hirasawa; Idha Kusumawati; Erika Mitsuta; Abdul Rahman; Aiko Saito; Haruka Tamamoto; Kazumasa Zaima; Noor Cholies Zaini; Hiroshi Morita
Alstiphyllanines I-O, ajmaline type alkaloids from Alstonia macrophylla showing vasorelaxant activity.
Bioorganic & medicinal chemistry 2012;20(11):3454-9.
2012: Alfarius E Nugroho; Wong Chin Piow; Osamu Shirota; Aty Widyawaruyanti; Wiwied Ekasari; A Hamid A Hadi; Yusuke Hirasawa; Toshio Kaneda; Hiroshi Morita
Antiplasmodial indole alkaloids from Leuconotis griffithii.
Journal of natural medicines 2012;66(2):350-3.
2012: Yoko Shimokawa; A Hamid A Hadi; Yusuke Hirasawa; Toshio Kaneda; Hiroshi Morita
Cuspidans A and B, two new stilbenoids from the bark of Gnetum cuspidatum.
Chemical & pharmaceutical bulletin 2012;60(6):790-2.
2012: Jun Deguchi; Wiwied Ekasari; Tomoe Hirahara; Yusuke Hirasawa; Motoo Shiro; Osamu Shirota; Aty Widyawaruyanti; Hiroshi Morita
New tricyclic alkaloids, cassiarins G, H, J, and K from leaves of Cassia siamea.
Chemical & pharmaceutical bulletin 2012;60(2):219-22.
2012: Fei He; Yusuke Hirasawa; Hiroshi Morita; Alfarius Eko Nugroho; Osamu Shirota; Chin Piow Wong; Haji Akber Aisa
Rupestines F-M, new guaipyridine sesquiterpene alkaloids from Artemisia rupestris.
Chemical & pharmaceutical bulletin 2012;60(2):213-8.
2011: Jun Deguchi; Wiwied Ekasari; Tomoe Hirahara; Yusuke Hirasawa; Toshio Honda; Shiori Oshimi; Osamu Shirota; Hiroshi Morita
Total synthesis of a novel tetracyclic alkaloid, cassiarin F from the flowers of Cassia siamea.
Organic letters 2011;13(16):4344-7.
2011: Hirotaka Matsuo; Yusuke Hirasawa; Intan Safinar Ismail; Nordin Hj Lajis; Ryuichi Okamoto; Kazumasa Zaima; Hiroshi Morita
New vasorelaxant indole alkaloids, villocarines A-D from Uncaria villosa.
Bioorganic & medicinal chemistry 2011;19(13):4075-9.
2011: Alfarius E Nugroho; Masatomo Sugai; Yusuke Hirasawa; Takahiro Hosoya; Khalijah Awang; A Hamid A Hadi; Wiwied Ekasari; Aty Widyawaruyanti; Hiroshi Morita
New antiplasmodial indole alkaloids from Hunteria zeylanica.
Bioorganic & medicinal chemistry letters 2011;21(11):3417-9.
2011: Adil Astulla; Yusuke Hirasawa; Abdul Rahman; Idha Kusumawati; Wiwied Ekasari; Aty Widyawaruyanti; Noor Cholies Zaini; Hiroshi Morita
Melidianolic acid A and B, new antimalarial acyclic diterpenes from Aphanamixis grandifolia.
Natural product communications 2011;6(3):323-6.
2011: Chin Piow Wong; Misae Shimada; Yuta Nagakura; Alfarius Eko Nugroho; Yusuke Hirasawa; Toshio Kaneda; Khalijah Awang; A Hamid A Hadi; Khalit Mohamad; Motoo Shiro; Hiroshi Morita
Ceramicines E-I, new limonoids from Chisocheton ceramicus.
Chemical & pharmaceutical bulletin 2011;59(3):407-11.
2011: Ahmad Kaleem Qureshi; Mat Ropi Mukhtar; Yusuke Hirasawa; Takahiro Hosoya; Alfarius Eko Nugroho; Hiroshi Morita; Osamu Shirota; Khalit Mohamad; A Hamid A Hadi; Marc Litaudon; Khalijah Awang
Neolamarckines A and B, new indole alkaloids from Neolamarckia cadamba.
Chemical & pharmaceutical bulletin 2011;59(2):291-3.
2010: Koichiro Koyama; Yusuke Hirasawa; Alfarius Eko Nugroho; Takahiro Hosoya; Teh Chin Hoe; Kit-Lam Chan; Hiroshi Morita
Alsmaphorazines A and B, novel indole alkaloids from Alstonia pneumatophora.
Organic letters 2010;12(18):4188-91.
2010: Yusuke Hirasawa; Mayumi Hara; Alfarius E Nugroho; Masatomo Sugai; Kazumasa Zaima; Nobuo Kawahara; Yukihiro Goda; Khalijah Awang; A Hamid A Hadi; Marc Litaudon; Hiroshi Morita
Bisnicalaterines B and C, atropisomeric bisindole alkaloids from Hunteria zeylanica, showing vasorelaxant activity.
The Journal of organic chemistry 2010;75(12):4218-23.
2010: Koichiro Koyama; Yusuke Hirasawa; Takahiro Hosoya; Teh Chin Hoe; Kit-Lam Chan; Hiroshi Morita
Alpneumines A-H, new anti-melanogenic indole alkaloids from Alstonia pneumatophora.
Bioorganic & medicinal chemistry 2010;18(12):4415-21.
2010: Hiroko Arai; Yusuke Hirasawa; Abdul Rahman; Idha Kusumawati; Noor Cholies Zaini; Seizo Sato; Chihiro Aoyama; Jiro Takeo; Hiroshi Morita
Alstiphyllanines E-H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter.
Bioorganic & medicinal chemistry 2010;18(6):2152-8.
2010: Yusuke Hirasawa; Tomokazu Shoji; Takashi Arai; Alfarius E Nugroho; Jun Deguchi; Takahiro Hosoya; Nahoko Uchiyama; Yukihiro Goda; Khalijah Awang; A Hamid A Hadi; Motoo Shiro; Hiroshi Morita
Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii.
Bioorganic & medicinal chemistry letters 2010;20(6):2021-4.
2010: Hiroshi Morita; Jun Deguchi; Yusuke Motegi; Seizo Sato; Chihiro Aoyama; Jiro Takeo; Motoo Shiro; Yusuke Hirasawa
Cyclic diarylheptanoids as Na+-glucose cotransporter (SGLT) inhibitors from Acer nikoense.
Bioorganic & medicinal chemistry letters 2010;20(3):1070-4.
2010: Takayuki Matsumoto; Tsuneo Kobayashi; Keiko Ishida; Yusuke Hirasawa; Hiroshi Morita; Toshio Honda; Katsuo Kamata
Vasodilator effect of Cassiarin A, a novel antiplasmodial alkaloid from Cassia siamea, in rat isolated mesenteric artery.
Biological & pharmaceutical bulletin 2010;33(5):844-8.
2009: Yusuke Hirasawa; Saori Miyama; Takahiro Hosoya; Koichiro Koyama; Abdul Rahman; Idha Kusumawati; Noor Cholies Zaini; Hiroshi Morita
Alasmontamine A, A first tetrakis monoterpene indole alkaloid from Tabernaemontana elegans.
Organic letters 2009;11(24):5718-21.
2009: Hiroshi Morita; Yuichiro Tomizawa; Jun Deguchi; Tokio Ishikawa; Hiroko Arai; Kazumasa Zaima; Takahiro Hosoya; Yusuke Hirasawa; Takayuki Matsumoto; Katsuo Kamata; Wiwied Ekasari; Aty Widyawaruyanti; Tutik Sri Wahyuni; Noor Cholies Zaini; Toshio Honda
Synthesis and structure-activity relationships of cassiarin A as potential antimalarials with vasorelaxant activity.
Bioorganic & medicinal chemistry 2009;17(24):8234-40.
2009: Intan Safinar Ismail; Yuta Nagakura; Yusuke Hirasawa; Takahiro Hosoya; Mohd Izwan Mohd Lazim; Nordin Hj Lajis; Motoo Shiro; Hiroshi Morita
Chrotacumines A-D, chromone alkaloids from Dysoxylum acutangulum.
Journal of natural products 2009;72(10):1879-83.
2009: Shiori Oshimi; Jun Deguchi; Yusuke Hirasawa; Wiwied Ekasari; Aty Widyawaruyanti; Tutik Sri Wahyuni; Noor Cholies Zaini; Osamu Shirota; Hiroshi Morita
Cassiarins C-E, antiplasmodial alkaloids from the flowers of Cassia siamea.
Journal of natural products 2009;72(10):1899-901.
2009: Kazumasa Zaima; Tomoko Hirata; Takahiro Hosoya; Yusuke Hirasawa; Koichiro Koyama; Abdul Rahman; Idha Kusumawati; Noor Cholies Zaini; Motoo Shiro; Hiroshi Morita
Biscarpamontamines A and B, an aspidosperma-iboga bisindole alkaloid and an aspidosperma-aspidosperma bisindole alkaloid, from Tabernaemontana sphaerocarpa.
Journal of natural products 2009;72(9):1686-90.
2009: Shiori Oshimi; Aki Takasaki; Yusuke Hirasawa; Takahiro Hosoya; Khalijah Awang; A Hamid A Hadi; Wiwied Ekasari; Aty Widyawaruyanti; Hiroshi Morita
Delaumonones A and B, new antiplasmodial quassinoids from Laumoniera bruceadelpha.
Chemical & pharmaceutical bulletin 2009;57(8):867-9.
2009: Alfarius E Nugroho; Yusuke Hirasawa; Nobuo Kawahara; Yukihiro Goda; Khalijah Awang; A Hamid A Hadi; Hiroshi Morita
Bisnicalaterine A, a vobasine-vobasine bisindole alkaloid from Hunteria zeylanica.
Journal of natural products 2009;72(8):1502-6.
2009: Hiroshi Morita; Tomoe Tsuchiya; Koji Kishibe; Sayaka Noya; Motoo Shiro; Yusuke Hirasawa
Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.
Bioorganic & medicinal chemistry letters 2009;19(13):3679-81.
2009: Yosuke Matsuno; Jun Deguchi; Takahiro Hosoya; Yusuke Hirasawa; Chieko Hirobe; Motoo Shiro; Hiroshi Morita
Sucutiniranes C-F, cassane-type diterpenes from Bowdichia nitida.
Journal of natural products 2009;72(5):976-9.
2009: Yusuke Hirasawa; Hiroko Arai; Kazumasa Zaima; Rice Oktarina; Abdul Rahman; Wiwied Ekasari; Aty Widyawaruyanti; Gunawan Indrayanto; Noor Cholies Zaini; Hiroshi Morita
Alstiphyllanines A-D, indole alkaloids from Alstonia macrophylla.
Journal of natural products 2009;72(2):304-7.
2009: Khalit Mohamad; Yusuke Hirasawa; Marc Litaudon; Khalijah Awang; A Hamid A Hadi; Koichi Takeya; Wiwied Ekasari; Aty Widyawaruyanti; Noor Cholies Zaini; Hiroshi Morita
Ceramicines B-D, new antiplasmodial limonoids from Chisocheton ceramicus.
Bioorganic & medicinal chemistry 2009;17(2):727-30.
2009: Hiroshi Morita; Yuichiro Tomizawa; Tomoe Tsuchiya; Yusuke Hirasawa; Toshihiro Hashimoto; Yoshinori Asakawa
Antimitotic activity of two macrocyclic bis(bibenzyls), isoplagiochins A and B from the Liverwort Plagiochila fruticosa.
Bioorganic & medicinal chemistry letters 2009;19(2):493-6.
2008: Yusuke Hirasawa; Tomoyuki Tanaka; Jun'ichi Kobayashi; Nobuo Kawahara; Yukihiro Goda; Hiroshi Morita
Malycorins A--C, New lycopodium alkaloids from Lycopodium phlegmaria.
Chemical & pharmaceutical bulletin 2008;56(10):1473-6.
2008: Adil Astulla; Kazumasa Zaima; Yosuke Matsuno; Yusuke Hirasawa; Wiwied Ekasari; Aty Widyawaruyanti; Noor Cholies Zaini; Hiroshi Morita
Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities.
Journal of natural medicines 2008;62(4):470-2.
2008: Koichiro Koyama; Yusuke Hirasawa; Kazumasa Zaima; Teh Chin Hoe; Kit-Lam Chan; Hiroshi Morita
Alstilobanines A-E, new indole alkaloids from Alstonia angustiloba.
Bioorganic & medicinal chemistry 2008;16(13):6483-8.
2008: Shiori Oshimi; Yuichiro Tomizawa; Yusuke Hirasawa; Toshio Honda; Wiwied Ekasari; Aty Widyawaruyanti; Marcellino Rudyanto; Gunawan Indrayanto; Noor Cholies Zaini; Hiroshi Morita
Chrobisiamone A, a new bischromone from Cassia siamea and a biomimetic transformation of 5-acetonyl-7-hydroxy-2-methylchromone into cassiarin A.
Bioorganic & medicinal chemistry letters 2008;18(13):3761-3.
2008: Yosuke Matsuno; Jun Deguchi; Yusuke Hirasawa; Kunio Ohyama; Hiroo Toyoda; Chieko Hirobe; Wiwied Ekasari; Aty Widyawaruyanti; Noor Cholies Zaini; Hiroshi Morita
Sucutiniranes A and B, new cassane-type diterpenes from Bowdichia nitida.
Bioorganic & medicinal chemistry letters 2008;18(13):3774-7.
2008: Yusuke Hirasawa; Eri Kato; Jun'ichi Kobayashi; Nobuo Kawahara; Yukihiro Goda; Motoo Shiro; Hiroshi Morita
Lycoparins A-C, new alkaloids from Lycopodium casuarinoides inhibiting acetylcholinesterase.
Bioorganic & medicinal chemistry 2008;16(11):6167-71.
2008: Shiori Oshimi; Kazumasa Zaima; Yosuke Matsuno; Yusuke Hirasawa; Toru Iizuka; Herra Studiawan; Gunawan Indrayanto; Noor Cholies Zaini; Hiroshi Morita
Studies on the constituents from the fruits of Phaleria macrocarpa.
Journal of natural medicines 2008;62(2):207-10.
2008: Hiroshi Morita; Yusuke Hirasawa; Akihiro Muto; Tadashi Yoshida; Setsuko Sekita; Osamu Shirota
Antimitotic quinoid triterpenes from Maytenus chuchuhuasca.
Bioorganic & medicinal chemistry letters 2008;18(3):1050-2.
2007: Koichiro Koyama; Yusuke Hirasawa; Jun'ichi Kobayashi; Hiroshi Morita
Cryptadines A and B, novel C27N3-type pentacyclic alkaloids from Lycopodium cryptomerinum.
Bioorganic & medicinal chemistry 2007;15(24):7803-8.
2007: Yusuke Hirasawa; Emi Izawa; Yosuke Matsuno; Nobuo Kawahara; Yukihiro Goda; Hiroshi Morita
Taxodistines A and B, abietane-type diterpenes from Taxodium distichum.
Bioorganic & medicinal chemistry letters 2007;17(21):5868-71.
2007: Hiroshi Morita; Maiko Enomoto; Yusuke Hirasawa; Toru Iizuka; Kazunori Ogawa; Nobuo Kawahara; Yukihiro Goda; Teruki Matsumoto; Koichi Takeya
Cyclonatsudamine A, a new vasodilator cyclic peptide from Citrus natsudaidai.
Bioorganic & medicinal chemistry letters 2007;17(19):5410-3.
2007: Yosuke Matsuno; Mariko Okamoto; Yusuke Hirasawa; Nobuo Kawahara; Yukihiro Goda; Motoo Shiro; Hiroshi Morita
Pordamacrines A and B, alkaloids from Daphniphyllum macropodum.
Journal of natural products 2007;70(9):1516-8.
2007: Hiroshi Morita; Shiori Oshimi; Yusuke Hirasawa; Koichiro Koyama; Toshio Honda; Wiwied Ekasari; Gunawan Indrayanto; Noor Cholies Zaini
Cassiarins A and B, novel antiplasmodial alkaloids from Cassia siamea.
Organic letters 2007;9(18):3691-3.
2007: Chee Yan Choo; Yusuke Hirasawa; Chiaki Karimata; Koichiro Koyama; Mitsuhiro Sekiguchi; Jun'ichi Kobayashi; Hiroshi Morita
Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase.
Bioorganic & medicinal chemistry 2007;15(4):1703-7.
2006: Hiroshi Morita; Michiko Eda; Toru Iizuka; Yusuke Hirasawa; Mitsuhiro Sekiguchi; Young Sook Yun; Hideji Itokawa; Koichi Takeya
Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis.
Bioorganic & medicinal chemistry letters 2006;16(17):4458-61.
2006: Yusuke Hirasawa; Jun'ichi Kobayashi; Hiroshi Morita
Lycoperine A, A novel C27N3-type pentacyclic alkaloid from Lycopodium hamiltonii, inhibiting acetylcholinesterase.
Organic letters 2006;8(1):123-6.
2005: Hiroshi Morita; Yusuke Hirasawa; Jun'ichi Kobayashi
Lycopodatines A-C, C(16)N alkaloids from Lycopodium inundatum.
Journal of natural products 2005;68(12):1809-12.