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Yasunobu Hirata

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Norihiko Ashigaki; Tomoya Hanatani; Yasunobu Hirata; Norio Aoyama; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Asuka Sekinishi; Jun-Ichi Suzuki; Yuko Tada; Chisato Takamura; Kouji Wakayama; Ryo Watanabe; Hirofumi Zempo; Mitsuaki Isobe
Periodontal bacteria aggravate experimental autoimmune myocarditis in mice.
Atsuko Nakayama; Hiroaki Sugiyama; Masao Takahashi; Jiro Ando; Katsuhito Fujiu; Kazuyoshi Hina; Yasunobu Hirata; Yasushi Imai; Toshiya Kojima; Ryozo Nagai
Radiofrequency catheter ablation of the accessory pathway adversely affected the left ventricular outflow tract pressure gradient in a patient with hypertrophic obstructive cardiomyopathy.
Naomi Ogawa; Shinichi Takamoto; Norifumi Takeda; Tsuyoshi Taketani; Yasushi Imai; Masayoshi Kato; Tetsuro Morota; Ryozo Nagai; Kan Nawata; Hiroshi Nishimura; Yasunobu Hirata
Circulating transforming growth factor β-1 level in Japanese patients with Marfan syndrome.

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2013: Norihiko Ashigaki; Tomoya Hanatani; Yasunobu Hirata; Norio Aoyama; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Asuka Sekinishi; Jun-Ichi Suzuki; Yuko Tada; Chisato Takamura; Kouji Wakayama; Ryo Watanabe; Hirofumi Zempo; Mitsuaki Isobe
Periodontal bacteria aggravate experimental autoimmune myocarditis in mice.
American journal of physiology. Heart and circulatory physiology 2013;304(5):H740-8.
2013: Atsuko Nakayama; Hiroaki Sugiyama; Masao Takahashi; Jiro Ando; Katsuhito Fujiu; Kazuyoshi Hina; Yasunobu Hirata; Yasushi Imai; Toshiya Kojima; Ryozo Nagai
Radiofrequency catheter ablation of the accessory pathway adversely affected the left ventricular outflow tract pressure gradient in a patient with hypertrophic obstructive cardiomyopathy.
International heart journal 2013;54(2):111-4.
2013: Naomi Ogawa; Shinichi Takamoto; Norifumi Takeda; Tsuyoshi Taketani; Yasushi Imai; Masayoshi Kato; Tetsuro Morota; Ryozo Nagai; Kan Nawata; Hiroshi Nishimura; Yasunobu Hirata
Circulating transforming growth factor β-1 level in Japanese patients with Marfan syndrome.
International heart journal 2013;54(1):23-6.
2012: Tetsu Tanaka; Yasunobu Hirata; Akiko Itai; Ryozo Nagai; Masahito Ogawa; Asuka Sekinishi; Jun-Ichi Suzuki; Mitsuaki Isobe
Inhibition of IκB phosphorylation prevents load-induced cardiac dysfunction in mice.
American journal of physiology. Heart and circulatory physiology 2012;303(12):H1435-45.
2012: Masahito Ogawa; Takaaki Senbonmatsu; Jun-Ichi Suzuki; Kiyoshi Takayama; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Impaired post-infarction cardiac remodeling in chronic kidney disease is due to excessive renin release.
Laboratory investigation; a journal of technical methods and pathology 2012;92(12):1766-76.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Masaaki Akahane; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Ryozo Nagai
How to demonstrate the reversibility of end-organ function before implantation of left ventricular assist device in INTERMACS profile 2 patients?
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(4):395-8.
2012: Jun-Ichi Suzuki; Kiyoshi Takayama; Ryo Watanabe; Yasunobu Hirata; Keiichi Hishikari; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Novel effects of macrolide antibiotics on cardiovascular diseases.
Cardiovascular therapeutics 2012;30(6):301-7.
2012: Taira Fukuda; Yasunobu Hirata; Haruko Iida; Kenichi Ikeda; Masayoshi Kato; Miwa Kurano; Koji Maemura; Nobuhito Masuda; Koshiro Monzen; Ryozo Nagai; Mika Nagasaki; Taro Shiga; Haruhito Takano; Tomofumi Tanaka; Kansei Uno; Yumiko Yamamoto; Hiroshi Yamashita; Toshiaki Nakajima
Cardiac rehabilitation decreases plasma pentraxin 3 in patients with cardiovascular diseases.
European journal of preventive cardiology 2012;19(6):1393-400.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
An elevated ratio of early to late diastolic filling velocity recovers after heart transplantation in a time-dependent manner.
Journal of cardiology 2012;60(4):295-300.
2012: Teruhiko Imamura; Toshiro Inaba; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Yasushi Imai; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Ryozo Nagai
Early decision for a left ventricular assist device implantation is necessary for patients with modifier A.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(3):301-4.
2012: Jun-Ichi Suzuki; Yasunobu Hirata; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Effects of immunoglobulin to prevent coronary allograft vasculopathy in heart transplantation.
Expert opinion on therapeutic targets 2012;16(8):783-9.
2012: Takehiro Takahashi; Zenshiro Tamaki; Takashi Taniguchi; Tetsuo Toyama; Aya Watanabe; Masafumi Watanabe; Eisuke Amiya; Yoshihide Asano; Masaru Hatano; Yasunobu Hirata; Yohei Ichimura; Shuichi Kawarasaki; Ryozo Nagai; Tomoko Nakao; Atsuko Ozeki; Shinichi Sato
Improvement of endothelial function in parallel with the amelioration of dry cough and dyspnea due to interstitial pneumonia by intravenous cyclophosphamide pulse therapy in patients with systemic sclerosis: a preliminary report of two cases.
Modern rheumatology / the Japan Rheumatism Association 2012;22(4):598-601.
2012: Naoko Kato; Keiko Kazuma; Koichiro Kinugawa; Taro Shiga; Norihiko Takeda; Masafumi Watanabe; Atsushi Yao; Masaru Hatano; Yasunobu Hirata; Yasushi Imai; Ryozo Nagai
Depressive symptoms are common and associated with adverse clinical outcomes in heart failure with reduced and preserved ejection fraction.
Journal of cardiology 2012;60(1):23-30.
2012: Teruhiko Imamura; Toshiro Inaba; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
A case of late-onset right ventricular failure after implantation of a continuous-flow left ventricular assist device.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2012;15(2):200-3.
2012: Masahiro Myojo; Hiroki Sato; Daigo Sawaki; Masao Takahashi; Jiro Ando; Hideo Fujita; Yasunobu Hirata; Hiroshi Iwata; Arihiro Kiyosue; Kohro Takahide; Ryozo Nagai
Prognostic implication of macrocytosis on adverse outcomes after coronary intervention.
Atherosclerosis 2012;221(1):148-53.
2012: Aiko Sakamoto; Masao Takahashi; Norifumi Takeda; Hideomi Yamada; Kazuhiko Koike; Haruki Kume; Daichi Maeda; Ryozo Nagai; Kan Saito; Yutaka Enomoto; Masashi Fukayama; Kenji Hirano; Yasunobu Hirata; Yukio Homma; Yumiko Hosoya; Yasushi Imai; Nobukazu Ishizaka
Idiopathic retroperitoneal fibrosis, inflammatory aortic aneurysm, and inflammatory pericarditis--retrospective analysis of 11 case histories.
Journal of cardiology 2012;59(2):139-46.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
Correction of hyponatremia by tolvaptan before left ventricular assist device implantation.
International heart journal 2012;53(6):391-3.
2012: Junichi Ishida; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Masaru Hatano; Yasunobu Hirata; Teruhiko Imamura; Toshiro Inaba; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Ryozo Nagai
Rapidly progressive cardiac allograft vasculopathy in early onset regressed with everolimus treatment in an adult cardiac recipient.
International heart journal 2012;53(6):388-90.
2012: Asuka Sekinishi; Jun-Ichi Suzuki; Ryo Watanabe; Norio Aoyama; Norihiko Ashigaki; Tomoya Hanatani; Yasunobu Hirata; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Periodontal pathogen Aggregatibacter actinomycetemcomitans deteriorates pressure overload-induced myocardial hypertrophy in mice.
International heart journal 2012;53(5):324-30.
2012: Taira Fukuda; Yasunobu Hirata; Haruko Iida; Miwa Kurano; Akihiro Matsumoto; Toshihiro Morita; Ryozo Nagai; Haruhito Takano; Hiroshi Yamashita; Toshiaki Nakajima
Cardiac output response to exercise in chronic cardiac failure patients.
International heart journal 2012;53(5):293-8.
2012: Toshiro Inaba; Koichiro Kinugawa; Hisataka Maki; Masaru Hatano; Yasunobu Hirata; Teruhiko Imamura; Tomoko Nakao; Taro Shiga; Takahiro Shiota; Makoto Sonoda; Junichi Suzuki; Katsu Takenaka; Tadashi Yamazaki; Atsushi Yao; Ryozo Nagai
Volumetric and functional assessment of ventricles in pulmonary hypertension on 3-dimensional echocardiography.
Circulation journal : official journal of the Japanese Circulation Society 2012;77(1):198-206.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
Preoperative levels of bilirubin or creatinine adjusted by age can predict their reversibility after implantation of left ventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2012;77(1):96-104.
2012: Tomoya Hanatani; Yasunobu Hirata; Norio Aoyama; Yuichi Izumi; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Jun-Ichi Suzuki; Mitsuaki Isobe
The periodontal pathogen Aggregatibacter actinomycetemcomitans deteriorates ventricular remodeling after myocardial infarction in mice.
International heart journal 2012;53(4):253-6.
2012: Taro Shiga; Atsushi Yao; Takashi Nishimura; Minoru Ono; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Ryozo Nagai
Combination evaluation of preoperative risk indices predicts requirement of biventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(12):2785-91.
2012: Kazuo Asada; Katsuhito Fujiu; Yasunobu Hirata; Yasushi Imai; Koichiro Kinugawa; Toshiya Kojima; Hiroaki Sugiyama; Takeki Suzuki; Ryozo Nagai
Intrathoracic impedance monitoring in patients with heart failure: correlation with dehydration and bleeding events.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(11):2592-8.
2012: Teruhiko Imamura; Toshiro Inaba; Hiroyuki Isayama; Koichiro Kinugawa; Kazuhiko Koike; Hisataka Maki; Dai Mohri; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Taro Shiga; Atsushi Yao; Ryozo Nagai
A case of pancreatic cancer after heart transplantation.
International heart journal 2012;53(3):205-7.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Hisataka Maki; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Taro Shiga; Atsushi Yao; Ryozo Nagai
Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient.
International heart journal 2012;53(3):199-201.
2012: Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Jun-Ichi Suzuki; Norio Aoyama; Tomoya Hanatani; Yasunobu Hirata; Yuichi Izumi; Mitsuaki Isobe
Porphyromonas gingivalis accelerates neointimal formation after arterial injury.
Journal of vascular research 2012;49(5):417-24.
2012: Rikuta Hamaya; Yasunobu Hirata; Akiko Itai; Naho Kobayashi; Ryozo Nagai; Masahito Ogawa; Jun-Ichi Suzuki; Mitsuaki Isobe
A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice.
International heart journal 2012;53(2):133-8.
2012: Teruhiko Imamura; Toshiro Inaba; Naoko Kato; Koichiro Kinugawa; Shunei Kyo; Hisataka Maki; Takashi Nishimura; Minoru Ono; Taro Shiga; Atsushi Yao; Miyoko Endo; Masaru Hatano; Yasunobu Hirata; Ryozo Nagai
Novel risk scoring system with preoperative objective parameters gives a good prediction of 1-year mortality in patients with a left ventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(8):1895-903.
2012: Makoto Sahara; Masataka Sata; Yasunobu Hirata; Toshihiro Morita; Ryozo Nagai
Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.
PloS one 2012;7(3):e33367.
2012: Katsura Soma; Yutaka Takazawa; Norihiko Takeda; Hiroshi Yamashita; Hajime Abe; Katsuhito Fujiu; Masashi Fukayama; Yasunobu Hirata; Toshiya Kojima; Hiroaki Semba; Yukako Shintani; Ryozo Nagai
Myocardial involvement in patients with osteogenesis imperfecta.
International heart journal 2012;53(1):75-7.
2012: Hiroaki Semba; Taro Shiga; Norihiko Takeda; Yumiko Terada; Yuichi Uchino; Akihiko Yonenaga; Hajime Abe; Eriko Hasumi; Yasunobu Hirata; Tsukasa Inajima; Hiroshi Iwata; Koichiro Kinugawa; Go Nishimura; Ryozo Nagai
Preliminary report of tolvaptan treatment in Japanese patients with heart failure.
International heart journal 2012;53(1):72-4.
2012: Jun-Ichi Suzuki; Yasunobu Hirata; Mitsuaki Isobe; Masahito Ogawa; Yoshiki Sakai; Ryozo Nagai
A prostacycline analog prevents chronic myocardial remodeling in murine cardiac allografts.
International heart journal 2012;53(1):64-7.
2011: Naomi Ogawa; Yuji K Takahashi; Shinichi Takamoto; Norifumi Takeda; Tsuyoshi Taketani; Shoji Tsuji; Tsutomu Yamazaki; Jun Goto; Kazuo Hara; Yasushi Imai; Masayoshi Kato; Takahide Kohro; Hiroyuki Morita; Tetsuro Morota; Ryozo Nagai; Kan Nawata; Hiroshi Nishimura; Yasunobu Hirata
Evaluating Japanese patients with the Marfan syndrome using high-throughput microarray-based mutational analysis of fibrillin-1 gene.
The American journal of cardiology 2011;108(12):1801-7.
2011: Satoshi Kinugasa; Tatsuo Sakai; Masafumi Takahashi; Akihiro Tojo; Harukuni Tsumura; Yasunobu Hirata; Toshiro Fujita
Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase.
Kidney international 2011;80(12):1328-38.
2011: Arihiro Kiyosue; Masahiro Myojo; Ryozo Nagai; Daisuke Nagata; Tomohiko Sato; Hiroshi Satonaka; Masao Takahashi; Yasunobu Hirata
Aldosterone-induced osteopontin gene transcription in vascular smooth muscle cells involves glucocorticoid response element.
Hypertension research : official journal of the Japanese Society of Hypertension 2011;34(12):1283-7.
2011: Takehiro Yamane; Keita Tamura; Yusuke Adachi; Kenjiro Hanaoka; Yasunobu Hirata; Yasushi Miyashita; Yasuaki Muramatsu; Tetsuo Nagano
Method for enhancing cell penetration of Gd3+-based MRI contrast agents by conjugation with hydrophobic fluorescent dyes.
Bioconjugate chemistry 2011;22(11):2227-36.
2011: Jun-Ichi Suzuki; Ryo Watanabe; Yasunobu Hirata; Ryuichi Morishita; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Autoimmune giant cell myocarditis: clinical characteristics, experimental models and future treatments.
Expert opinion on therapeutic targets 2011;15(10):1163-72.
2011: Takumi J Matsubara; Minoru Ono; Taro Shiga; Atsushi Yao; Masaru Hatano; Yasunobu Hirata; Hiroshi Iwata; Koichiro Kinugawa; Ryozo Nagai
Progressive coronary artery-pulmonary artery fistula after size-mismatch cardiac transplantation.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2011;57(4):346-7.
2011: Kimie Tanaka; Daisuke Nagata; Yasunobu Hirata; Yasuhiko Tabata; Ryozo Nagai; Masataka Sata
Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice.
Atherosclerosis 2011;215(2):366-73.
2011: Jun-ichi Suzuki; Masahito Ogawa; Susumu Muto; Akiko Itai; Mitsuaki Isobe; Yasunobu Hirata; Ryozo Nagai
Novel IkB kinase inhibitors for treatment of nuclear factor-kB-related diseases.
Expert opinion on investigational drugs 2011;20(3):395-405.
2011: Jun-Ichi Suzuki; Masahito Ogawa; Susumu Muto; Akiko Itai; Yasunobu Hirata; Mitsuaki Isobe; Ryozo Nagai
Effects of specific chemical suppressors of plasminogen activator inhibitor-1 in cardiovascular diseases.
Expert opinion on investigational drugs 2011;20(2):255-64.
2011: Masahito Ogawa; Jun-ichi Suzuki; Yoichi Yamaguchi; Susumu Muto; Akiko Itai; Yasunobu Hirata; Mitsuaki Isobe; Ryozo Nagai
The effects of pharmacologic plasminogen activator inhibitor-1 inhibition in acute and chronic rejection in murine cardiac allografts.
Transplantation 2011;91(1):21-6.
2011: Tetsuya Saito; Masao Takahashi; Norihiko Takeda; Masafumi Watanabe; Hiroshi Yamashita; Kuni Ohtomo; Hideo Fujita; Yasunobu Hirata; Arihiro Kiyosue; Toshiya Kojima; Shuhei Komatsu; Koji Maemura; Takayoshi Matsumura; Ryozo Nagai
Successful blood sampling through azygos continuation with interrupted inferior vena cava. A case report and review of the literature.
International heart journal 2011;52(5):327-30.
2011: Jun-Ichi Suzuki; Kiyoshi Takayama; Ryo Watanabe; Yasunobu Hirata; Ryozo Nagai; Masahito Ogawa; Mitsuaki Isobe
Roles of prostaglandin E2 in cardiovascular diseases.
International heart journal 2011;52(5):266-9.
2011: Eriko Hasumi; Yasunobu Hirata; Yasushi Imai; Hiroshi Iwata; Jiro Ando; Hideo Fujita; Katsuhito Fujiu; Kan Saito; Ryozo Nagai
Diagnostic efficacy of coronary CT angiography as a follow-up modality for procedure-related coronary dissection.
International heart journal 2011;52(4):240-2.
2011: Masaru Hatano; Yasunobu Hirata; Koichiro Kinugawa; Atsushi Yao; Ryozo Nagai
Acute effect of sildenafil is maintained in pulmonary arterial hypertension patients chronically treated with bosentan.
International heart journal 2011;52(4):233-9.
2011: Takehiro Kamo; Takayoshi Matsumura; Yasunobu Hirata; Ryozo Nagai
Multiple pulmonary artery fistulas causing partial lung edema.
Internal medicine (Tokyo, Japan) 2011;50(11):1259-60.
2011: Naoko Kato; Keiko Kazuma; Koichiro Kinugawa; Masaru Hatano; Yasunobu Hirata; Satomi Seki; Taro Shiga; Atsushi Yao; Ryozo Nagai
Quality of life as an independent predictor for cardiac events and death in patients with heart failure.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(7):1661-9.
2011: Masaru Hatano; Koichiro Kinugawa; Taro Shiga; Naoko Kato; Miyoko Endo; Motoyuki Hisagi; Takashi Nishimura; Atsushi Yao; Yasunobu Hirata; Shunei Kyo; Minoru Ono; Ryozo Nagai
Less frequent opening of the aortic valve and a continuous flow pump are risk factors for postoperative onset of aortic insufficiency in patients with a left ventricular assist device.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(5):1147-55.
2011: Taro Shiga; Koichiro Kinugawa; Masaru Hatano; Atsushi Yao; Takashi Nishimura; Miyoko Endo; Naoko Kato; Yasunobu Hirata; Shunei Kyo; Minoru Ono; Ryozo Nagai
Age and preoperative total bilirubin level can stratify prognosis after extracorporeal pulsatile left ventricular assist device implantation.
Circulation journal : official journal of the Japanese Circulation Society 2011;75(1):121-8.
2010: Kazuki Kiyose; Kenjiro Hanaoka; Daihi Oushiki; Tomomi Nakamura; Mayumi Kajimura; Makoto Suematsu; Hiroaki Nishimatsu; Takehiro Yamane; Takuya Terai; Yasunobu Hirata; Tetsuo Nagano
Hypoxia-sensitive fluorescent probes for in vivo real-time fluorescence imaging of acute ischemia.
Journal of the American Chemical Society 2010;132(45):15846-8.
2010: Arihiro Kiyosue; Yasunobu Hirata; Jiro Ando; Hideo Fujita; Toshihiro Morita; Masao Takahashi; Daisuke Nagata; Kohro Takahide; Yasushi Imai; Ryozo Nagai
Plasma cystatin C concentration reflects the severity of coronary artery disease in patients without chronic kidney disease.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(11):2441-7.
2010: Toshiaki Nakajima; Miwa Kurano; Takaaki Hasegawa; Haruhito Takano; Haruko Iida; Tomohiro Yasuda; Taira Fukuda; Haruhiko Madarame; Kansei Uno; Kentaro Meguro; Taro Shiga; Mina Sagara; Taiji Nagata; Koji Maemura; Yasunobu Hirata; Tatsuya Yamasoba; Ryozo Nagai
Pentraxin3 and high-sensitive C-reactive protein are independent inflammatory markers released during high-intensity exercise.
European journal of applied physiology 2010;110(5):905-13.
2010: Jun-Ichi Suzuki; Norio Aoyama; Masahito Ogawa; Yasunobu Hirata; Yuichi Izumi; Ryozo Nagai; Mitsuaki Isobe
Periodontitis and cardiovascular diseases.
Expert opinion on therapeutic targets 2010;14(10):1023-7.
2010: Jun-Ichi Suzuki; Masahito Ogawa; Noriko Tamura; Yasuhiro Maejima; Kiyoshi Takayama; Koji Maemura; Kazuki Honda; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
A critical role of sympathetic nerve regulation for the treatment of impaired daily rhythm in hypertensive Dahl rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(10):1060-5.
2010: Takuya Nakajima; Keiichi Hishikari; Masahito Ogawa; Ryo Watanabe; Jun-Ichi Suzuki; Ayako Nagashima; Mayumi Masumura; Kiyoshi Takayama; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Clarithromycin attenuates myocardial ischemia-reperfusion injury.
Expert opinion on therapeutic targets 2010;14(9):881-93.
2010: Masaru Hatano; Atsushi Yao; Taro Shiga; Koichiro Kinugawa; Yasunobu Hirata; Ryozo Nagai
Imatinib mesylate has the potential to exert its efficacy by down-regulating the plasma concentration of platelet-derived growth factor in patients with pulmonary arterial hypertension.
International heart journal 2010;51(4):272-6.
2010: Makoto Sahara; Masataka Sata; Toshihiro Morita; Toshiaki Nakajima; Yasunobu Hirata; Ryozo Nagai
A phosphodiesterase-5 inhibitor vardenafil enhances angiogenesis through a protein kinase G-dependent hypoxia-inducible factor-1/vascular endothelial growth factor pathway.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1315-24.
2010: Hiroshi Iwata; Masataka Sata; Jiro Ando; Hideo Fujita; Toshihiro Morita; Daigo Sawaki; Masao Takahashi; Yoichiro Hirata; Shuichiro Takanashi; Minoru Tabata; Yasunobu Hirata; Ryozo Nagai
Impact of primitive cells in intracoronary thrombi on lesion prognosis: temporal analysis of cellular constituents of thrombotic material obtained from patients with acute coronary syndrome.
Heart (British Cardiac Society) 2010;96(10):748-55.
2010: Masataka Togashi; Yasuteru Urano; Hirotatsu Kojima; Takuya Terai; Kenjiro Hanaoka; Kazuei Igarashi; Yasunobu Hirata; Tetsuo Nagano
Sensitive detection of acrolein in serum using time-resolved luminescence.
Organic letters 2010;12(8):1704-7.
2010: Keiichi Hishikari; Ryo Watanabe; Masahito Ogawa; Jun-Ichi Suzuki; Mayumi Masumura; Tomoko Shimizu; Kiyoshi Takayama; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Early treatment with clarithromycin attenuates rat autoimmune myocarditis via inhibition of matrix metalloproteinase activity.
Heart (British Cardiac Society) 2010;96(7):523-7.
2010: Yasunobu Hirata
Significance of B-type natriuretic peptide measurement in patients with chronic kidney disease.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(4):632-3.
2010: Arihiro Kiyosue; Yasunobu Hirata; Jiro Ando; Hideo Fujita; Toshihiro Morita; Masao Takahashi; Daisuke Nagata; Kohro Takahide; Yasushi Imai; Ryozo Nagai
Relationship between renal dysfunction and severity of coronary artery disease in Japanese patients.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(4):786-91.
2010: Jun-ichi Suzuki; Masahito Ogawa; Kiyoshi Takayama; Yoshiaki Taniyama; Ryuichi Morishita; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice.
Journal of the American College of Cardiology 2010;55(9):904-13.
2010: Masao Takahashi; Etsu Suzuki; Shigeyoshi Oba; Hiroaki Nishimatsu; Kenjiro Kimura; Tetsuo Nagano; Ryozo Nagai; Yasunobu Hirata
Adipose tissue-derived stem cells inhibit neointimal formation in a paracrine fashion in rat femoral artery.
American journal of physiology. Heart and circulatory physiology 2010;298(2):H415-23.
2010: Yuichi Uchino; Masafumi Watanabe; Yasunobu Hirata; Kunihiro Shigematsu; Tetsuro Miyata; Ryozo Nagai
Efficacy of renal revascularization in a patient with fibromuscular renal artery stenosis and heart failure.
International heart journal 2010;51(6):432-5.
2010: Shigeyoshi Oba; Shintaro Kumano; Etsu Suzuki; Hiroaki Nishimatsu; Masao Takahashi; Hajime Takamori; Masatoshi Kasuya; Yousuke Ogawa; Kenichiro Sato; Kenjiro Kimura; Yukio Homma; Yasunobu Hirata; Toshiro Fujita
miR-200b precursor can ameliorate renal tubulointerstitial fibrosis.
PloS one 2010;5(10):e13614.
2010: Yasunobu Hirata; Daisuke Nagata; Etsu Suzuki; Hiroaki Nishimatsu; Jun-Ichi Suzuki; Ryozo Nagai
Diagnosis and treatment of endothelial dysfunction in cardiovascular disease.
International heart journal 2010;51(1):1-6.
2010: Daisuke Nagata; Yasunobu Hirata
The role of AMP-activated protein kinase in the cardiovascular system.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(1):22-8.
2009: Masahito Ogawa; Jun-Ichi Suzuki; Yasunobu Hirata; Ryozo Nagai; Mitsuaki Isobe
A critical role of COX-2 in the progression of neointimal formation after wire injury in mice.
Expert opinion on therapeutic targets 2009;13(5):505-11.
2009: Daisuke Nagata; Arihiro Kiyosue; Masao Takahashi; Hiroshi Satonaka; Kimie Tanaka; Masataka Sata; Tetsuo Nagano; Ryozo Nagai; Yasunobu Hirata
A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(2):133-9.
2009: Akihiro Masuzawa; Takayuki Ohno; Shinichi Takamoto; Noboru Motomura; Minoru Ono; Hideo Fujita; Jiro Ando; Toshihiro Morita; Yasunobu Hirata; Ryozo Nagai; Akira Hirose; Takashi Shigeeda; Satoshi Kato; Makoto Araie
In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery.
Journal of cardiology 2009;53(1):86-93.
2009: Kensuke Asaba; Arinobu Tojo; Maristela Lika Onozato; Satoshi Kinugasa; Hiroki Miyazaki; Kazuhisa Miyashita; Yoshio Uehara; Yasunobu Hirata; Kenjiro Kimura; Atsuo Goto; Masao Omata; Toshiro Fujita
Long-term renal prognosis of IgA nephropathy with therapeutic trend shifts.
Internal medicine (Tokyo, Japan) 2009;48(11):883-90.
2008: Yasutomi Higashikuni; Tamon Nagashima; Nobukazu Ishizaka; Koichiro Kinugawa; Yasunobu Hirata; Ryozo Nagai
Right aortic arch with mirror image branching and vascular ring.
International journal of cardiology 2008;130(1):e53-5.
2008: Kazuto Nakamura; Nobutaka Koibuchi; Hiroaki Nishimatsu; Yasutomi Higashikuni; Yasunobu Hirata; Kiyotaka Kugiyama; Ryozo Nagai; Masataka Sata
Candesartan ameliorates cardiac dysfunction observed in angiotensin-converting enzyme 2-deficient mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(10):1953-61.
2008: T Kariya; Yasushi Imai; Arata Murakami; Sachito Minegishi; Tatsuo Katori; Hitoshi Kato; Kohsuke Ajiki; Yasunobu Hirata; Ryozo Nagai
Images in cardiovascular medicine. Markedly dilated right heart 17 years after initial treatment repaired by total right ventricular exclusion and total cavopulmonary connection.
Circulation 2008;118(9):e133-5.
2008: Yasunobu Hirata; Arihiro Kiyosue; Masao Takahashi; Hiroshi Satonaka; Daisuke Nagata; Masataka Sata; Etsu Suzuki; Ryozo Nagai
Progression of renal dysfunction in patients with cardiovascular disease.
Current cardiology reviews 2008;4(3):198-202.
2008: Hiroaki Nishimatsu; Etsu Suzuki; Ryo Takeda; Masao Takahashi; Shigeyoshi Oba; Kenjiro Kimura; Tetsuo Nagano; Yasunobu Hirata
Blockade of endogenous proinflammatory cytokines ameliorates endothelial dysfunction in obese Zucker rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(4):737-43.
2008: Miwa Matsumoto; Masataka Sata; Daiju Fukuda; Kimie Tanaka; Masaaki Soma; Yasunobu Hirata; Ryozo Nagai
Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice.
Atherosclerosis 2008;197(2):524-33.
2008: Kimie Tanaka; Masataka Sata; Takeshi Natori; Joo-ri Kim-Kaneyama; Kiyoshi Nose; Motoko Shibanuma; Yasunobu Hirata; Ryozo Nagai
Circulating progenitor cells contribute to neointimal formation in nonirradiated chimeric mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(2):428-36.
2008: Po-Hsun Huang; Masataka Sata; Hiroaki Nishimatsu; Makoto Sumi; Yasunobu Hirata; Ryozo Nagai
Pioglitazone ameliorates endothelial dysfunction and restores ischemia-induced angiogenesis in diabetic mice.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(1):46-52.
2007: Takayuki Ohno; Shinichi Takamoto; Noboru Motomura; Minoru Ono; Jiro Ando; Toshihiro Morita; Hideo Fujita; Yasunobu Hirata; Ryozo Nagai; Takashi Shigeeda; Akira Hirose
Coronary artery bypass grafting versus coronary implantation of sirolimus-eluting stents in patients with diabetic retinopathy.
The Annals of thoracic surgery 2007;84(5):1474-8.
2007: Daisuke Nagata; Yasunobu Hirata
[Molecular mechanism of cardiovascular damage induced by aldosterone].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(9):1339-46.
2007: Kazuto Nakamura; Masataka Sata; Hiroshi Iwata; Yoshiki Sakai; Yasunobu Hirata; Kiyotaka Kugiyama; Ryozo Nagai
A synthetic small molecule, ONO-1301, enhances endogenous growth factor expression and augments angiogenesis in the ischaemic heart.
Clinical science (London, England : 1979) 2007;112(12):607-16.
2007: Masafumi Watanabe; Yasunobu Hirata
[Combination therapy of beta blockers for heart failure].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 5():129-33.
2007: Norifumi Takeda; Yasunobu Hirata
[Efficacy and adverse reactions of atrial natriuretic peptide on kidney and cardiovascular system].
Nihon rinsho. Japanese journal of clinical medicine 2007;65 Suppl 5():110-4.
2007: Yoshinori Seko; Akihiro Matsumoto; Taira Fukuda; Yasushi Imai; Tsutomu Fujimura; Hikari Taka; Reiko Mineki; Kimie Murayama; Yasunobu Hirata; Ryozo Nagai
A case of neonatal lupus erythematosus presenting delayed dilated cardiomyopathy with circulating autoantibody to annexin A6.
International heart journal 2007;48(3):407-15.
2007: Takayuki Ohno; Shinichi Takamoto; Jiro Ando; Toshihiro Morita; Hideo Fujita; Yasunobu Hirata; Takashi Shigeeda; Akira Hirose; Ryozo Nagai
Diabetic retinopathy and coronary implantation of sirolimus-eluting stents.
Journal of interventional cardiology 2007;20(2):122-31.
2007: Ibuki Shirakawa; Masataka Sata; Akio Saiura; Yukari Kaneda; Hisako Yashiro; Yasunobu Hirata; Makuuchi Masatoshi; Ryozo Nagai
Atorvastatin attenuates transplant-associated coronary arteriosclerosis in a murine model of cardiac transplantation.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2007;61(2-3):154-9.
2007: Makoto Sahara; Masataka Sata; Toshihiro Morita; Kazuto Nakamura; Yasunobu Hirata; Ryozo Nagai
Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.
Circulation 2007;115(4):509-17.
2007: Kazuo Asada; Masaru Hatano; Norihiko Takeda; Yasutomi Higashikuni; Kan Saito; Nobukazu Ishizaka; Yasunobu Hirata; Ryozo Nagai
Giant left coronary artery aneurysm in a patient with mixed connective tissue disease.
Internal medicine (Tokyo, Japan) 2007;46(15):1267-8.
2006: Takayuki Ohno; Jiro Ando; Minoru Ono; Toshihiro Morita; Noboru Motomura; Yasunobu Hirata; Shinichi Takamoto
The beneficial effect of coronary-artery-bypass surgery on survival in patients with diabetic retinopathy.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2006;30(6):881-6.
2006: Minami Abe; Masataka Sata; Etsu Suzuki; Ryo Takeda; Masao Takahashi; Hiroaki Nishimatsu; Daisuke Nagata; Kenji Kangawa; Hisayuki Matsuo; Ryozo Nagai; Yasunobu Hirata
Effects of adrenomedullin on acute ischaemia-induced collateral development and mobilization of bone-marrow-derived cells.
Clinical science (London, England : 1979) 2006;111(6):381-7.
2006: Makoto Sahara; Toshiyuki Takahashi; Yasushi Imai; Toshiaki Nakajima; Atsushi Yao; Toshihiro Morita; Yasunobu Hirata; Ryozo Nagai
New insights in the treatment strategy for pulmonary arterial hypertension.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2006;20(5):377-86.
2006: Aiko Sakamoto; Koji Okamoto; Nobukazu Ishizaka; Kazuaki Tejima; Yasunobu Hirata; Ryozo Nagai
18F-fluorodeoxyglucose positron emission tomography in a case of retroperitoneal fibrosis.
International heart journal 2006;47(4):645-50.
2006: Yasunobu Hirata
[Nitric oxide].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 5():254-8.
2006: Takuya Terai; Kazuya Kikuchi; Shin-ya Iwasawa; Takao Kawabe; Yasunobu Hirata; Yasuteru Urano; Tetsuo Nagano
Modulation of luminescence intensity of lanthanide complexes by photoinduced electron transfer and its application to a long-lived protease probe.
Journal of the American Chemical Society 2006;128(21):6938-46.
2006: Takayoshi Matsumura; Akihiro Matsumoto; Minoru Ohno; Shinya Suzuki; Miki Ohta; Etsu Suzuki; Katsu Takenaka; Yasunobu Hirata; Toshiro Fujita; Ryozo Nagai
A case of cholesterol embolism confirmed by skin biopsy and successfully treated with statins and steroids.
The American journal of the medical sciences 2006;331(5):280-3.
2006: Atsuko Kamijo; Takeshi Sugaya; Akihisa Hikawa; Masaya Yamanouchi; Yasunobu Hirata; Toshihiko Ishimitsu; Atsushi Numabe; Masao Takagi; Hiroshi Hayakawa; Fumiko Tabei; Tokuichiro Sugimoto; Naofumi Mise; Masao Omata; Kenjiro Kimura
Urinary liver-type fatty acid binding protein as a useful biomarker in chronic kidney disease.
Molecular and cellular biochemistry 2006;284(1-2):175-82.
2006: Tsutomu Shimizu; Norifumi Takeda; Masao Takahashi; Yasushi Imai; Nobukazu Ishizaka; Yasunobu Hirata; Ryozo Nagai
Subarachnoid hemorrhage from mycotic aneurysms.
Internal medicine (Tokyo, Japan) 2006;45(20):1189-90.
2006: Makoto Sahara; Toshiyuki Takahashi; Toshihiro Morita; Atsushi Yao; Yu Nagashima; Yasunobu Hirata; Ryozo Nagai
Three-vessel coronary artery disease complicated with congestive heart failure in a highly aged patient with tetralogy of Fallot having undergone palliative surgeries.
Internal medicine (Tokyo, Japan) 2006;45(20):1147-51.
2006: Ryo Takeda; Hiroaki Nishimatsu; Etsu Suzuki; Hiroshi Satonaka; Daisuke Nagata; Shigeyoshi Oba; Masataka Sata; Masao Takahashi; Yuji Yamamoto; Yasuo Terauchi; Takashi Kadowaki; Kenji Kangawa; Tadaichi Kitamura; Ryozo Nagai; Yasunobu Hirata
Ghrelin improves renal function in mice with ischemic acute renal failure.
Journal of the American Society of Nephrology : JASN 2006;17(1):113-21.
2005: Haruhito Takano; Toshihiro Morita; Haruko Iida; Ken-ichi Asada; Masayoshi Kato; Kansei Uno; Ken Hirose; Akihiro Matsumoto; Katsu Takenaka; Yasunobu Hirata; Fumio Eto; Ryozo Nagai; Yoshiaki Sato; Toshiaki Nakajima
Hemodynamic and hormonal responses to a short-term low-intensity resistance exercise with the reduction of muscle blood flow.
European journal of applied physiology 2005;95(1):65-73.
2005: Makoto Sahara; Masataka Sata; Yumi Matsuzaki; Kimie Tanaka; Toshihiro Morita; Yasunobu Hirata; Hideyuki Okano; Ryozo Nagai
Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury.
Stem cells (Dayton, Ohio) 2005;23(7):874-8.
2005: Kimie Tanaka; Masataka Sata; Daiju Fukuda; Yoshihiro Suematsu; Noboru Motomura; Shinichi Takamoto; Yasunobu Hirata; Ryozo Nagai
Age-associated aortic stenosis in apolipoprotein E-deficient mice.
Journal of the American College of Cardiology 2005;46(1):134-41.
2005: Hiroshi Satonaka; Etsu Suzuki; Hiroshi Hayakawa; Hiroaki Nishimatsu; Daisuke Nagata; Shigeyoshi Oba; Atsuko Kamijo; Ryo Takeda; Masao Takahashi; Yuji Yamamoto; Kenjiro Kimura; Yasunobu Hirata
Long-term effect of imidapril hydrochloride compared with dilazep hydrochloride administration on blood pressure and renal function in patients with chronic glomerulonephritis.
International heart journal 2005;46(4):701-10.
2005: Hiroaki Nishimatsu; Etsu Suzuki; Hiroshi Satonaka; Ryo Takeda; Masao Omata; Toshiro Fujita; Ryozo Nagai; Tadaichi Kitamura; Yasunobu Hirata
Endothelial dysfunction and hypercontractility of vascular myocytes are ameliorated by fluvastatin in obese Zucker rats.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1770-6.
2005: Eita Sasaki; Hirotatsu Kojima; Hiroaki Nishimatsu; Yasuteru Urano; Kazuya Kikuchi; Yasunobu Hirata; Tetsuo Nagano
Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organs.
Journal of the American Chemical Society 2005;127(11):3684-5.
2005: Ryo Takeda; Etsu Suzuki; Hiroshi Satonaka; Shigeyoshi Oba; Hiroaki Nishimatsu; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Blockade of endogenous cytokines mitigates neointimal formation in obese Zucker rats.
Circulation 2005;111(11):1398-406.
2005: Atsuko Kamijo; Takeshi Sugaya; Akihisa Hikawa; Masaya Yamanouchi; Yasunobu Hirata; Toshihiko Ishimitsu; Atsushi Numabe; Masao Takagi; Hiroshi Hayakawa; Fumiko Tabei; Tokuichiro Sugimoto; Naofumi Mise; Kenjiro Kimura
Clinical evaluation of urinary excretion of liver-type fatty acid-binding protein as a marker for the monitoring of chronic kidney disease: a multicenter trial.
The Journal of laboratory and clinical medicine 2005;145(3):125-33.
2005: Norifumi Takeda; Toshiyuki Takahashi; Yoshinori Seko; Koji Maemura; Hideki Nakasone; Kei Sakamoto; Yasunobu Hirata; Ryozo Nagai
Takayasu myocarditis mediated by cytotoxic T lymphocytes.
Internal medicine (Tokyo, Japan) 2005;44(3):256-60.
2005: Shinsuke Muto; Yasunobu Hirata
[Edema in heart disease].
Nihon rinsho. Japanese journal of clinical medicine 2005;63(1):68-72.
2004: Atsuko Kamijo; Takeshi Sugaya; Akihisa Hikawa; Mitsuhiro Okada; Fumikazu Okumura; Masaya Yamanouchi; Akiko Honda; Masaru Okabe; Tomoya Fujino; Yasunobu Hirata; Masao Omata; Ritsuko Kaneko; Hiroshi Fujii; Akiyoshi Fukamizu; Kenjiro Kimura
Urinary excretion of fatty acid-binding protein reflects stress overload on the proximal tubules.
The American journal of pathology 2004;165(4):1243-55.
2004: Yasunobu Hirata
[Role of NO in essential hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():518-21.
2004: Hiroaki Nishimatsu; Yasunobu Hirata
[Renal effects of ghrelin].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():380-3.
2004: Yasunobu Hirata
[Effects of adrenomedullin on NO release].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():229-32.
2004: Yasunobu Hirata
[Role of natriuretic peptides in blood pressure regulation].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():56-9.
2004: Masayoshi Kato; Akihiro Matsumoto; Toshiaki Nakajima; Ken Hirose; Kuniaki Iwasawa; Katsu Takenaka; Hiroshi Yamashita; Seiryo Sugiura; Yasunobu Hirata; Ryozo Nagai
Amlodipine increases nitric oxide production in exhaled air during exercise in patients with essential hypertension.
American journal of hypertension 2004;17(9):729-33.
2004: Daisuke Nagata; Ryo Takeda; Masataka Sata; Hiroshi Satonaka; Etsu Suzuki; Tetsuo Nagano; Yasunobu Hirata
AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation.
Circulation 2004;110(4):444-51.
2004: Etsu Suzuki; Hiroshi Satonaka; Hiroaki Nishimatsu; Shigeyoshi Oba; Ryo Takeda; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Myocyte enhancer factor 2 mediates vascular inflammation via the p38-dependent pathway.
Circulation research 2004;95(1):42-9.
2004: Yasunobu Hirata
[Natriuretic peptide].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 6():189-93.
2004: Masataka Sata; Hiroaki Nishimatsu; Jun-ichi Osuga; Kimie Tanaka; Nobukazu Ishizaka; Shun Ishibashi; Yasunobu Hirata; Ryozo Nagai
Statins augment collateral growth in response to ischemia but they do not promote cancer and atherosclerosis.
Hypertension 2004;43(6):1214-20.
2004: Pei Niu; Takayuki Shindo; Hiroshi Iwata; Satoshi Iimuro; Norifumi Takeda; Yuelan Zhang; Aya Ebihara; Yoshihiro Suematsu; Kenji Kangawa; Yasunobu Hirata; Ryozo Nagai
Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage.
Circulation 2004;109(14):1789-94.
2004: Hiroshi Satonaka; Etsu Suzuki; Hiroaki Nishimatsu; Shigeyoshi Oba; Ryo Takeda; Atsuo Goto; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation.
Circulation research 2004;94(5):693-700.
2004: Yasunobu Hirata
[NO and hypertension].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 3():243-6.
2004: Yukio Hiroi; Katsuhito Fujiu; Shuhei Komatsu; Makoto Sonoda; Yasunari Sakomura; Yasushi Imai; Yumi Oishi; Fumitaka Nakamura; Kohsuke Ajiki; Noriyuki Hayami; Yuji Murakawa; Minoru Ohno; Yasunobu Hirata; Kuni Ohtomo; Ryozo Nagai
Carvedilol therapy improved left ventricular function in a patient with arrhythmogenic right ventricular cardiomyopathy.
Japanese heart journal 2004;45(1):169-77.
2004: Atsuko Kamijo; Kenjiro Kimura; Takeshi Sugaya; Masaya Yamanouchi; Akihisa Hikawa; Norihito Hirano; Yasunobu Hirata; Atsuo Goto; Masao Omata
Urinary fatty acid-binding protein as a new clinical marker of the progression of chronic renal disease.
The Journal of laboratory and clinical medicine 2004;143(1):23-30.
2003: Takefumi Nojiri; Hiroyuki Morita; Yasushi Imai; Koji Maemura; Minoru Ohno; Ken Ogasawara; Tadanori Aizawa; Akira Saito; Doubun Hayashi; Yasunobu Hirata; Takao Sugiyama; Tsutomu Yamazaki; Ryozo Nagai
Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese.
International journal of cardiology 2003;92(2-3):181-6.
2003: Takeshi Natori; Masataka Sata; Miwa Washida; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
Nicotine enhances neovascularization and promotes tumor growth.
Molecules and cells 2003;16(2):143-6.
2003: Kimie Tanaka; Masataka Sata; Yasunobu Hirata; Ryozo Nagai
Diverse contribution of bone marrow cells to neointimal hyperplasia after mechanical vascular injuries.
Circulation research 2003;93(8):783-90.
2003: Keiko Fukino; Masataka Sata; Yoshinori Seko; Yasunobu Hirata; Ryozo Nagai
Genetic background influences therapeutic effectiveness of VEGF.
Biochemical and biophysical research communications 2003;310(1):143-7.
2003: Pei Niu; Takayuki Shindo; Hiroshi Iwata; Aya Ebihara; Yoshihiro Suematsu; Yuelan Zhang; Norifumi Takeda; Satoshi Iimuro; Yasunobu Hirata; Ryozo Nagai
Accelerated cardiac hypertrophy and renal damage induced by angiotensin II in adrenomedullin knockout mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(9):731-6.
2003: Masataka Sata; Kimie Tanaka; Nobukazu Ishizaka; Yasunobu Hirata; Ryozo Nagai
Absence of p53 leads to accelerated neointimal hyperplasia after vascular injury.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(9):1548-52.
2003: Akio Saiura; Masataka Sata; Miwa Washida; Yasuhiko Sugawara; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
Little evidence for cell fusion between recipient and donor-derived cells.
The Journal of surgical research 2003;113(2):222-7.
2003: Tomohiro Harada; Yasushi Imai; Takefumi Nojiri; Hiroyuki Morita; Doubun Hayashi; Koji Maemura; Keiko Fukino; Daiji Kawanami; Go Nishimura; Kensuke Tsushima; Koshiro Monzen; Tadashi Yamazaki; Satoshi Mitsuyama; Takahiko Shintani; Narimasa Watanabe; Kumiko Seto; Takao Sugiyama; Fumitaka Nakamura; Minoru Ohno; Yasunobu Hirata; Tsutomu Yamazaki; Ryozo Nagai
A common Ile 823 Met variant of ATP-binding cassette transporter A1 gene (ABCA1) alters high density lipoprotein cholesterol level in Japanese population.
Atherosclerosis 2003;169(1):105-12.
2003: Minami Abe; Masataka Sata; Hiroaki Nishimatsu; Daisuke Nagata; Etsu Suzuki; Yasuo Terauchi; Takashi Kadowaki; Naoto Minamino; Kenji Kangawa; Hisayuki Matsuo; Yasunobu Hirata; Ryozo Nagai
Adrenomedullin augments collateral development in response to acute ischemia.
Biochemical and biophysical research communications 2003;306(1):10-5.
2003: Mayumi Minami; Keiichiro Atarashi; Akihiro Ishiyama; Yasunobu Hirata; Atsuo Goto; Masao Omata
Effects of cholesterol-lowering therapy on pressor hyperreactivity to stress in hypercholesterolemic patients.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(4):273-80.
2003: Hiroaki Nishimatsu; Yasunobu Hirata; Takayuki Shindo; Hiroki Kurihara; Etsu Suzuki; Masataka Sata; Hiroshi Satonaka; Ryo Takeda; Daisuke Nagata; Masao Kakoki; Hiroshi Hayakawa; Kenji Kangawa; Hisayuki Matsuo; Tadaichi Kitamura; Ryozo Nagai
Endothelial responses of the aorta from adrenomedullin transgenic mice and knockout mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26 Suppl():S79-84.
2003: Yukio Hiroi; Tomoko Nakao; Naoyuki Tsuchiya; Norihiko Takeda; Koji Maemura; Fumitaka Nakamura; Minoru Ohno; Yasunobu Hirata; Ryozo Nagai
Exacerbation of Lambert-Eaton myasthenic syndrome caused by an L-type Ca2+ channel antagonist.
Japanese heart journal 2003;44(1):139-44.
2002: Atsuko Kamijo; Kenjiro Kimura; Takeshi Sugaya; Masaya Yamanouchi; Hiromi Hase; Tomoyo Kaneko; Yasunobu Hirata; Atsuo Goto; Toshiro Fujita; Masao Omata
Urinary free fatty acids bound to albumin aggravate tubulointerstitial damage.
Kidney international 2002;62(5):1628-37.
2002: Takeshi Natori; Masataka Sata; Miwa Washida; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells.
Biochemical and biophysical research communications 2002;297(4):1058-61.
2002: Etsu Suzuki; Hiroaki Nishimatsu; Daisuke Nagata; Hiroshi Satonaka; Atsuo Goto; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Constitutive activation of proto-oncogen protein p21 induces cell cycle arrest in the G1 phase in contact-inhibited vascular endothelial cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(5):773-8.
2002: Masataka Sata; Akihiro Takahashi; Kimie Tanaka; Miwa Washida; Nobukazu Ishizaka; Junya Ako; Masao Yoshizumi; Yasuyoshi Ouchi; Takahiro Taniguchi; Yasunobu Hirata; Mitsuhiro Yokoyama; Ryozo Nagai; Kenneth Walsh
Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a p21(WAF1)-dependent pathway.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1305-9.
2002: Takayuki Shindo; Ichiro Manabe; Yasushi Fukushima; Kazuyuki Tobe; Kenichi Aizawa; Saku Miyamoto; Keiko Kawai-Kowase; Nobuo Moriyama; Yasushi Imai; Hayato Kawakami; Hiroaki Nishimatsu; Takashi Ishikawa; Toru Suzuki; Hiroyuki Morita; Koji Maemura; Masataka Sata; Yasunobu Hirata; Masayuki Komukai; Hiroyuki Kagechika; Takashi Kadowaki; Masahiko Kurabayashi; Ryozo Nagai
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.
Nature medicine 2002;8(8):856-63.
2002: Masataka Sata; Yasunobu Hirata; Ryozo Nagai
Role of Fas/Fas ligand interaction in ischemia-induced collateral vessel growth.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(4):577-82.
2002: Taiji Nagata; Akihiro Matsumoto; Yoshio Uehara; Goh Tanaka; Hitoshi Oonuma; Kei Hara; Kouichi Igarashi; Hisanori Hazama; Yasunobu Hirata; Yasushi Shiratori; Masao Omata
Oxygenation abnormalities in normoxemic patients with mild liver cirrhosis.
Internal medicine (Tokyo, Japan) 2002;41(6):435-40.
2002: Etsu Suzuki; Hiroaki Nishimatsu; Hiroshi Satonaka; Kenneth Walsh; Atsuo Goto; Masao Omata; Toshiro Fujita; Ryozo Nagai; Yasunobu Hirata
Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes.
Circulation research 2002;90(9):1004-11.
2002: Hiroaki Nishimatsu; Yasunobu Hirata; Takayuki Shindo; Hiroki Kurihara; Masao Kakoki; Daisuke Nagata; Hiroshi Hayakawa; Hiroshi Satonaka; Masataka Sata; Arinobu Tojo; Etsu Suzuki; Kenji Kangawa; Hisayuki Matsuo; Tadaichi Kitamura; Ryozo Nagai
Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury: studies on transgenic/knockout mice of adrenomedullin gene.
Circulation research 2002;90(6):657-63.
2002: Haruo Mitani; Nobukazu Ishizaka; Tadanori Aizawa; Minoru Ohno; Shin-ichi Usui; Toru Suzuki; Toshihiro Amaki; Ichiro Mori; Yasushi Nakamura; Misako Sato; Masaomi Nangaku; Yasunobu Hirata; Ryozo Nagai
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage.
Hypertension 2002;39(4):838-43.
2002: Masataka Sata; Akio Saiura; Atsushi Kunisato; Arinobu Tojo; Seiji Okada; Takeshi Tokuhisa; Hisamaru Hirai; Makuuchi Masatoshi; Yasunobu Hirata; Ryozo Nagai
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis.
Nature medicine 2002;8(4):403-9.
2002: Noriyuki Suzuki; Hirotatsu Kojima; Yasuteru Urano; Kazuya Kikuchi; Yasunobu Hirata; Tetsuo Nagano
Orthogonality of calcium concentration and ability of 4,5-diaminofluorescein to detect NO.
The Journal of biological chemistry 2002;277(1):47-9.
2002: Tomohiro Harada; Teruhiko Aoyagi; Yoko Endo; Kansei Uno; Katsu Takenaka; Fumitaka Nakamura; Makoto Sonoda; Toshiyuki Takahashi; Tadashi Yamazaki; Yukio Hiroi; Minoru Ohno; Yasunobu Hirata; Ryozo Nagai
Effusive constrictive pericarditis due to rheumatoid arthritis revealed by pericardiocentesis with simultaneous pressure recording--a case report.
Angiology 2002;53(1):105-8.
2002: Masataka Sata; Yasunobu Hirata; Ryozo Nagai
[Circulating recipient cells contribute to graft coronary arteriosclerosis].
Journal of cardiology 2002;39(1):48-9.
2001: Akio Saiura; Masataka Sata; Yasunobu Hirata; Ryozo Nagai; Makuuchi Masatoshi
Tranilast inhibits transplant-associated coronary arteriosclerosis in a murine model of cardiac transplantation.
European journal of pharmacology 2001;433(2-3):163-8.
2001: Mika Matsushita; Masayoshi Shichiri; T Imai; M Iwashina; H Tanaka; N Takasu; Yasunobu Hirata
Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues.
Journal of hypertension 2001;19(12):2185-90.
2001: Shingo Maeda; Masao Akanuma; Yuzo Mitsuno; Yasunobu Hirata; Keiji Ogura; Hideo Yoshida; Yasushi Shiratori; Masao Omata
Distinct mechanism of Helicobacter pylori-mediated NF-kappa B activation between gastric cancer cells and monocytic cells.
The Journal of biological chemistry 2001;276(48):44856-64.
2001: Yoshio Oh-hashi; Takayuki Shindo; Yukiko Kurihara; Takasuke Imai; Yuhui Wang; Hiroyuki Morita; Yasushi Imai; Yuji Kayaba; Hiroaki Nishimatsu; Y Suematsu; Yasunobu Hirata; Yoshio Yazaki; Ryozo Nagai; Tomoyuki Kuwaki; Hiroki Kurihara
Elevated sympathetic nervous activity in mice deficient in alphaCGRP.
Circulation research 2001;89(11):983-90.
2001: Hiroaki Nishimatsu; Yasunobu Hirata; Hiroshi Hayakawa; Daisuke Nagata; Hiroshi Satonaka; Etsu Suzuki; S Horie; T Takeuchi; Nobutaka Ohta; Yukio Homma; Shigeru Minowada; Ryozo Nagai; K Kawabe; Tadaichi Kitamura
Effects of intracavernous administration of adrenomedullin on erectile function in rats.
Peptides 2001;22(11):1913-8.
2001: Masataka Sata; Seiryo Sugiura; Masao Yoshizumi; Yasuyoshi Ouchi; Yasunobu Hirata; Ryozo Nagai
Acute and chronic smooth muscle cell apoptosis after mechanical vascular injury can occur independently of the Fas-death pathway.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(11):1733-7.
2001: Masataka Sata; Hiroaki Nishimatsu; Etsu Suzuki; S Sugiura; M Yoshizumi; Y Ouchi; Yasunobu Hirata; Ryozo Nagai
Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2530-2.
2001: Takayuki Shindo; Yukiko Kurihara; Hiroaki Nishimatsu; Nobuo Moriyama; Masao Kakoki; Y Wang; Yasuharu Imai; Aya Ebihara; Tomoyuki Kuwaki; Kihwan Ju; Naoto Minamino; Kenji Kangawa; T Ishikawa; M Fukuda; Y Akimoto; H Kawakami; T Imai; Hiroyuki Morita; Yoshio Yazaki; Ryozo Nagai; Yasunobu Hirata; Hiroki Kurihara
Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene.
Circulation 2001;104(16):1964-71.
2001: Kenji Harada; Takao Shimizu; Yasuyuki Sugishita; Atsushi Yao; Jun-Ichi Suzuki; Katsu Takenaka; Yasunobu Hirata; Ryozo Nagai; Tokiharu Takahashi
Hypertrophic cardiomyopathy with midventricular obstruction and apical aneurysm: a case report.
Japanese circulation journal 2001;65(10):915-9.
2001: Tomohiro Harada; Fumitaka Nakamura; Yasuo Ikeda; S Usui; Naoyuki Tsuchiya; Minoru Ohno; Yasunobu Hirata; Ryozo Nagai
Successful catheter intervention for acute coronary syndrome in a patient with antiphospholipid syndrome.
Japanese heart journal 2001;42(5):627-31.
2001: Yasunobu Hirata; A Matsumoto; T Aoyagi; K Yamaoki; Issei Komuro; Takahiro Suzuki; T Ashida; T Sugiyama; Yusuke Hada; Iwao Kuwajima; M Nishinaga; H Akioka; O Nakajima; Ryozo Nagai; Yoshio Yazaki
Measurement of plasma brain natriuretic peptide level as a guide for cardiac overload.
Cardiovascular research 2001;51(3):585-91.
2001: Hiroaki Nishimatsu; Etsu Suzuki; Daisuke Nagata; Nobuo Moriyama; Hiroshi Satonaka; Kenneth Walsh; Masataka Sata; Kenji Kangawa; Hisayuki Matsuo; Atsuo Goto; Tadaichi Kitamura; Yasunobu Hirata
Adrenomedullin induces endothelium-dependent vasorelaxation via the phosphatidylinositol 3-kinase/Akt-dependent pathway in rat aorta.
Circulation research 2001;89(1):63-70.
2001: Shingo Maeda; Motoyuki Otsuka; Yasunobu Hirata; Yuzo Mitsuno; Hideo Yoshida; Yasushi Shiratori; Yasuhiko Masuho; Masami Muramatsu; Naohiko Seki; Masao Omata
cDNA microarray analysis of Helicobacter pylori-mediated alteration of gene expression in gastric cancer cells.
Biochemical and biophysical research communications 2001;284(2):443-9.
2001: Yasunobu Hirata
[Pulmonary hypertension in endothelial NO synthase knockout mice].
Nihon rinsho. Japanese journal of clinical medicine 2001;59(6):1081-5.
2001: Yoshihiro Suematsu; Toshiya Ohtsuka; Yasunobu Hirata; Katsuhide Maeda; K Imanaka; Shinichi Takamoto
L-Arginine given after ischaemic preconditioning can enhance cardioprotection in isolated rat hearts.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2001;19(6):873-9.
2001: N Arai; A Matsumoto; N Nishikawa; K Yonekura; Y Eto; Yukihiro Kuwada; S Sugiura; Katsu Takenaka; Yasunobu Hirata; Ryozo Nagai; T Aoyagi
Beta-blocker therapy improved symptoms and exercise capacity in a patient with dynamic intra-right ventricular obstruction: an atypical Form of double-chambered right ventricle.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2001;14(6):650-3.
2001: Yasunobu Hirata; Shingo Maeda; Yuzo Mitsuno; Masao Akanuma; Yutaka Yamaji; Keiji Ogura; Hideo Yoshida; Yasushi Shiratori; Masao Omata
Helicobacter pylori activates the cyclin D1 gene through mitogen-activated protein kinase pathway in gastric cancer cells.
Infection and immunity 2001;69(6):3965-71.
2001: K Chisaki; Toshiaki Nakajima; Kuniaki Iwasawa; Haruko Iida; A Matsumoto; M Tada; Y Komatsu; K Hirose; K Miyamoto; Yukichi Okuda; Y Shiratori; Atsuo Goto; Yasunobu Hirata; Ryozo Nagai; Masao Omata
Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases.
Japanese heart journal 2001;42(3):339-53.
2001: Hirotatsu Kojima; M Hirotani; N Nakatsubo; Kazuya Kikuchi; Yasuteru Urano; T Higuchi; Yasunobu Hirata; Tetsuo Nagano
Bioimaging of nitric oxide with fluorescent indicators based on the rhodamine chromophore.
Analytical chemistry 2001;73(9):1967-73.
2001: M Shichiri; Yasunobu Hirata
Antiangiogenesis signals by endostatin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1044-53.
2001: Shinya Ishimaru; Masayoshi Shichiri; S Mineshita; Yasunobu Hirata
Role of endothelin-1/endothelin receptor system in endotoxic shock rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(2):119-26.
2001: Yuhui Wang; J Chen; Y Wang; C W Taylor; Yasunobu Hirata; H Hagiwara; Katsuhiko Mikoshiba; Teruhiko Toyo-Oka; Masao Omata; Y Sakaki
Crucial role of type 1, but not type 3, inositol 1,4,5-trisphosphate (IP(3)) receptors in IP(3)-induced Ca(2+) release, capacitative Ca(2+) entry, and proliferation of A7r5 vascular smooth muscle cells.
Circulation research 2001;88(2):202-9.
2001: Hiroaki Iwasaki; Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells.
Endocrinology 2001;142(2):564-72.
2001: Daisuke Nagata; Etsu Suzuki; Hiroaki Nishimatsu; Hiroshi Satonaka; Atsuo Goto; Masao Omata; Yasunobu Hirata
Transcriptional activation of the cyclin D1 gene is mediated by multiple cis-elements, including SP1 sites and a cAMP-responsive element in vascular endothelial cells.
The Journal of biological chemistry 2001;276(1):662-9.
2000: M Doi; Masayoshi Shichiri; K Katsuyama; Fumiaki Marumo; Yasunobu Hirata
Cytokine-activated p42/p44 MAP kinase is involved in inducible nitric oxide synthase gene expression independent from NF-kappaB activation in vascular smooth muscle cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(6):659-67.
2000: M Doi; Masayoshi Shichiri; M Yoshida; Fumiaki Marumo; Yasunobu Hirata
Suppression of integrin alpha(v) expression by endothelin-1 in vascular smooth muscle cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(6):643-9.
2000: Masataka Sata; Yasuhiro Maejima; F Adachi; Keiko Fukino; Akio Saiura; Seiryo Sugiura; Teruhiko Aoyagi; Yasushi Imai; H Kurihara; K Kimura; M Omata; M Makuuchi; Yasunobu Hirata; Ryozo Nagai
A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia.
Journal of molecular and cellular cardiology 2000;32(11):2097-104.
2000: Daisuke Nagata; Etsu Suzuki; Hiroaki Nishimatsu; Masao Yoshizumi; T Mano; Kenneth Walsh; Masataka Sata; Masao Kakoki; Atsuo Goto; Masao Omata; Yasunobu Hirata
Cyclin A downregulation and p21(cip1) upregulation correlate with GATA-6-induced growth arrest in glomerular mesangial cells.
Circulation research 2000;87(8):699-704.
2000: Masao Kakoki; Yasunobu Hirata; Hiroshi Hayakawa; Etsu Suzuki; Daisuke Nagata; Hiroaki Nishimatsu; Kenjiro Kimura; Atsuo Goto; Masao Omata
Effects of vasodilatory antihypertensive agents on endothelial dysfunction in rats with ischemic acute renal failure.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(5):527-33.
2000: Masataka Sata; Masao Kakoki; Daisuke Nagata; Hiroaki Nishimatsu; Etsu Suzuki; T Aoyagi; S Sugiura; H Kojima; Tetsuo Nagano; Kenji Kangawa; Hisayuki Matsuo; Masao Omata; Ryozo Nagai; Yasunobu Hirata
Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism.
Hypertension 2000;36(1):83-8.
2000: Shingo Maeda; Hideo Yoshida; Keiji Ogura; Yuzo Mitsuno; Yasunobu Hirata; Yutaka Yamaji; Masao Akanuma; Yasushi Shiratori; Masao Omata
H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells.
Gastroenterology 2000;119(1):97-108.
2000: Masayoshi Shichiri; M Yokokura; Fumiaki Marumo; Yasunobu Hirata
Endothelin-1 inhibits apoptosis of vascular smooth muscle cells induced by nitric oxide and serum deprivation via MAP kinase pathway.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):989-97.
2000: Etsu Suzuki; Daisuke Nagata; M Yoshizumi; Masao Kakoki; Atsuo Goto; Masao Omata; Yasunobu Hirata
Reentry into the cell cycle of contact-inhibited vascular endothelial cells by a phosphatase inhibitor. Possible involvement of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.
The Journal of biological chemistry 2000;275(5):3637-44.
2000: M Matsushita; Yasunobu Hirata
[von Hippel-Lindau disease].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 2():692-5.
2000: Hiroaki Iwasaki; Satoru Eguchi; Hiroo Ueno; Fumiaki Marumo; Yasunobu Hirata
Mechanical stretch stimulates growth of vascular smooth muscle cells via epidermal growth factor receptor.
American journal of physiology. Heart and circulatory physiology 2000;278(2):H521-9.
2000: Masao Kakoki; Yasunobu Hirata; H Hayakawa; Etsu Suzuki; Daisuke Nagata; Arinobu Tojo; Hiroaki Nishimatsu; N Nakanishi; Y Hattori; K Kikuchi; T Nagano; Masao Omata
Effects of tetrahydrobiopterin on endothelial dysfunction in rats with ischemic acute renal failure.
Journal of the American Society of Nephrology : JASN 2000;11(2):301-9.
2000: H Iwasaki; Yasunobu Hirata
[Gene of atrial natriuretic peptide].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():574-9.
2000: T Imai; Yasunobu Hirata
[Nitric oxide].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():462-5.
2000: M Doi; Masayoshi Shichiri; Yasunobu Hirata
[Endothelin].
Nihon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():75-9.
1999: Satoru Eguchi; Hiroaki Iwasaki; H Ueno; Gerald D Frank; Evangeline D Motley-Johnson; K Eguchi; Fumiaki Marumo; Yasunobu Hirata; Tadashi Inagami
Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt.
The Journal of biological chemistry 1999;274(52):36843-51.
1999: Masayoshi Shichiri; Yasunobu Hirata
[Endothelin].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():398-400.
1999: K Matsuda; Tadahiko Masaki; S Ishii; Hideomi Yamashita; Tomomi Watanabe; Hirokazu Nagawa; Tetsuichiro Muto; Yasunobu Hirata; Kenjiro Kimura; Somei Kojima
Possible associations of rectal carcinoma with Schistosoma japonicum infection and membranous nephropathy: a case report with a review.
Japanese journal of clinical oncology 1999;29(11):576-81.
1999: H Iwasaki; S Eguchi; H Ueno; Fumiaki Marumo; Yasunobu Hirata
Endothelin-mediated vascular growth requires p42/p44 mitogen-activated protein kinase and p70 S6 kinase cascades via transactivation of epidermal growth factor receptor.
Endocrinology 1999;140(10):4659-68.
1999: Masao Kakoki; A Matsumoto; Daisuke Nagata; Naoshi Kobayakawa; Kenjiro Kimura; Shin-ichi Momomura; Yasunobu Hirata
Analysis of nitric oxide in the exhaled air of patients with chronic glomerulonephritis.
Clinical nephrology 1999;52(2):83-90.
1999: Masayoshi Shichiri; H Kato; M Doi; Fumiaki Marumo; Yasunobu Hirata
Induction of max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis.
Molecular endocrinology (Baltimore, Md.) 1999;13(8):1353-63.
1999: Satoru Eguchi; Hiroaki Iwasaki; Yasunobu Hirata; Gerald D Frank; Evangeline D Motley-Johnson; Tadashi Yamakawa; Kotaro Numaguchi; Tadashi Inagami
Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II.
European journal of pharmacology 1999;376(1-2):203-6.
1999: Toru Hosoda; Issei Komuro; Ichiro Shiojima; Yukio Hiroi; M Harada; Yuji Murakawa; Yasunobu Hirata; Yoshio Yazaki
Familial atrial septal defect and atrioventricular conduction disturbance associated with a point mutation in the cardiac homeobox gene CSX/NKX2-5 in a Japanese patient.
Japanese circulation journal 1999;63(5):425-6.
1999: K Katsuyama; Masayoshi Shichiri; H Kato; T Imai; Fumiaki Marumo; Yasunobu Hirata
Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells.
Endocrinology 1999;140(5):2183-90.
1999: Teruhiko Aoyagi; K Yonekura; Y Eto; A Matsumoto; I Yokoyama; Seiryo Sugiura; S Momomura; Yasunobu Hirata; D L Baker; M Periasamy
The sarcoplasmic reticulum Ca2+-ATPase (SERCA2) gene promoter activity is decreased in response to severe left ventricular pressure-overload hypertrophy in rat hearts.
Journal of molecular and cellular cardiology 1999;31(4):919-26.
1999: Daisuke Nagata; Yasunobu Hirata; Etsu Suzuki; Masao Kakoki; Hiroshi Hayakawa; Atsuo Goto; T Ishimitsu; Naoto Minamino; Y Ono; Kenji Kangawa; Hisayuki Matsuo; Masao Omata
Hypoxia-induced adrenomedullin production in the kidney.
Kidney international 1999;55(4):1259-67.
1999: Etsu Suzuki; Daisuke Nagata; Masao Kakoki; Hiroshi Hayakawa; Atsuo Goto; Masao Omata; Yasunobu Hirata
Molecular mechanisms of endothelin-1-induced cell-cycle progression: involvement of extracellular signal-regulated kinase, protein kinase C, and phosphatidylinositol 3-kinase at distinct points.
Circulation research 1999;84(5):611-9.
1999: Masao Kakoki; Yasunobu Hirata; H Hayakawa; Arinobu Tojo; Daisuke Nagata; Etsu Suzuki; Kenjiro Kimura; Atsuo Goto; K Kikuchi; Tetsuo Nagano; Masao Omata
Effects of hypertension, diabetes mellitus, and hypercholesterolemia on endothelin type B receptor-mediated nitric oxide release from rat kidney.
Circulation 1999;99(9):1242-8.
1999: Mutsuhiko Minami; Keiichiro Atarashi; Akihiro Ishiyama; Yasunobu Hirata; Atsuo Goto; Masao Omata
Pressor hyperreactivity to mental and hand-grip stresses in patients with hypercholesterolemia.
Journal of hypertension 1999;17(2):185-92.
1999: Masao Kakoki; Yasunobu Hirata; Hiroshi Hayakawa; Hiroaki Nishimatsu; Y Suzuki; Daisuke Nagata; Etsu Suzuki; Kazuya Kikuchi; Tetsuo Nagano; Masao Omata
Effects of vasodilatory beta-adrenoceptor antagonists on endothelium-derived nitric oxide release in rat kidney.
Hypertension 1999;33(1 Pt 2):467-71.
1999: Satoru Eguchi; Hiroaki Iwasaki; Tadashi Inagami; Kotaro Numaguchi; Tadashi Yamakawa; Evangeline D Motley-Johnson; Kiyoshi Owada; Fumiaki Marumo; Yasunobu Hirata
Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells.
Hypertension 1999;33(1 Pt 2):201-6.
1999: N Suenobu; Masayoshi Shichiri; M Iwashina; Fumiaki Marumo; Yasunobu Hirata
Natriuretic peptides and nitric oxide induce endothelial apoptosis via a cGMP-dependent mechanism.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(1):140-6.
1999: A Matsumoto; Yasunobu Hirata; Masao Kakoki; Daisuke Nagata; Shin-ichi Momomura; Tokuichiro Sugimoto; Hitoshi Tagawa; M Omata
Increased excretion of nitric oxide in exhaled air of patients with chronic renal failure.
Clinical science (London, England : 1979) 1999;96(1):67-74.
1998: N Nakatsubo; Hirotatsu Kojima; K Sakurai; Kazuya Kikuchi; H Nagoshi; Yasunobu Hirata; T Akaike; H Maeda; Yasuteru Urano; T Higuchi; Tetsuo Nagano
Improved nitric oxide detection using 2,3-diaminonaphthalene and its application to the evaluation of novel nitric oxide synthase inhibitors.
Biological & pharmaceutical bulletin 1998;21(12):1247-50.
1998: K Katsuyama; Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
NO inhibits cytokine-induced iNOS expression and NF-kappaB activation by interfering with phosphorylation and degradation of IkappaB-alpha.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(11):1796-802.
1998: K Katsuyama; Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
Role of nuclear factor-kappaB activation in cytokine- and sphingomyelinase-stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells.
Endocrinology 1998;139(11):4506-12.
1998: M Iwashina; M Shichiri; Fumiaki Marumo; Yasunobu Hirata
Transfection of inducible nitric oxide synthase gene causes apoptosis in vascular smooth muscle cells.
Circulation 1998;98(12):1212-8.
1998: S Oba; Kenjiro Kimura; Naoe Suzuki; Naobumi Mise; Arinobu Tojo; Kazuhisa Miyashita; Y Konno; Yasunobu Hirata; Atsuo Goto; Masao Omata
Relevance of periglomerular myofibroblasts in progression of human glomerulonephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1998;32(3):419-25.
1998: H Iwasaki; S Eguchi; Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
Adrenomedullin as a novel growth-promoting factor for cultured vascular smooth muscle cells: role of tyrosine kinase-mediated mitogen-activated protein kinase activation.
Endocrinology 1998;139(8):3432-41.
1998: H Iwasaki; S Eguchi; Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
Down-regulation of adenylate cyclase coupled to adrenomedullin receptor in vascular smooth muscle cells.
European journal of pharmacology 1998;352(1):131-4.
1998: Hirotatsu Kojima; N Nakatsubo; Kazuya Kikuchi; S Kawahara; Yutaka Kirino; H Nagoshi; Yasunobu Hirata; Tetsuo Nagano
Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins.
Analytical chemistry 1998;70(13):2446-53.
1998: N Nakatsubo; Hirotatsu Kojima; Kazuya Kikuchi; H Nagoshi; Yasunobu Hirata; D Maeda; Y Imai; Tatsuro Irimura; Tetsuo Nagano
Direct evidence of nitric oxide production from bovine aortic endothelial cells using new fluorescence indicators: diaminofluoresceins.
FEBS letters 1998;427(2):263-6.
1998: Satoru Eguchi; Kotaro Numaguchi; Hiroaki Iwasaki; T Matsumoto; Tadashi Yamakawa; Hirotoshi Utsunomiya; Evangeline D Motley-Johnson; H Kawakatsu; Kiyoshi Owada; Yasunobu Hirata; Fumiaki Marumo; Tadashi Inagami
Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells.
The Journal of biological chemistry 1998;273(15):8890-6.
1998: Hirotatsu Kojima; K Sakurai; Kazuya Kikuchi; S Kawahara; Yutaka Kirino; H Nagoshi; Yasunobu Hirata; Tetsuo Nagano
Development of a fluorescent indicator for nitric oxide based on the fluorescein chromophore.
Chemical & pharmaceutical bulletin 1998;46(2):373-5.
1998: Masayoshi Shichiri; J M Sedivy; Fumiaki Marumo; Yasunobu Hirata
Endothelin-1 is a potent survival factor for c-Myc-dependent apoptosis.
Molecular endocrinology (Baltimore, Md.) 1998;12(2):172-80.
1998: H Iwasaki; S Eguchi; Fumiaki Marumo; Yasunobu Hirata
Endothelin-1 stimulates DNA synthesis of vascular smooth-muscle cells through transactivation of epidermal growth factor receptor.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S182-4.
1998: Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
Endothelin-B receptor-mediated suppression of endothelial apoptosis.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S138-41.
1997: Hirotatsu Kojima; K Sakurai; Kazuya Kikuchi; S Kawahara; Yutaka Kirino; H Nagoshi; Yasunobu Hirata; T Akaike; H Maeda; Tetsuo Nagano
Development of a fluorescent indicator for the bioimaging of nitric oxide.
Biological & pharmaceutical bulletin 1997;20(12):1229-32.
1997: Kenjiro Kimura; S Inokuchi; T Sugaya; Naoe Suzuki; H Yoneda; Isao Shirato; Naobumi Mise; S Oba; Kazuhisa Miyashita; Arinobu Tojo; Yasunobu Hirata; Atsuo Goto; Tatsuo Sakai; K Murakami; Masao Omata
Location and action of angiotensin II type 1 receptor in the renal microcirculation.
Kidney international. Supplement 1997;63():S201-4.
1997: Masayoshi Shichiri; H Kato; Fumiaki Marumo; Yasunobu Hirata
Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells.
Hypertension 1997;30(5):1198-203.
1997: V Bremer; Arinobu Tojo; K Kimura; Yasunobu Hirata; Atsuo Goto; Takeshi Nagamatsu; Yoshihisa Suzuki; Masao Omata
Role of nitric oxide in rat nephrotoxic nephritis: comparison between inducible and constitutive nitric oxide synthase.
Journal of the American Society of Nephrology : JASN 1997;8(11):1712-21.
1997: Masayoshi Shichiri; S Adachi; J M Sedivy; Fumiaki Marumo; Yasunobu Hirata
Biphasic regulation of the preproendothelin-1 gene by c-myc.
Endocrinology 1997;138(11):4584-90.
1997: T Nishimori; M Tsujino; K Sato; T Imai; Fumiaki Marumo; Yasunobu Hirata
Dexamethasone-induced up-regulation of adrenomedullin and atrial natriuretic peptide genes in cultured rat ventricular myocytes.
Journal of molecular and cellular cardiology 1997;29(8):2125-30.
1997: Shigeyoshi Ohba; Kenjiro Kimura; Naobumi Mise; Y Konno; Naoe Suzuki; Kazuhisa Miyashita; Arinobu Tojo; Yasunobu Hirata; Yoshio Uehara; Keiichiro Atarashi; Atsuo Goto; Masao Omata
Differential localization of s and e antigens in hepatitis B virus-associated glomerulonephritis.
Clinical nephrology 1997;48(1):44-7.
1997: H Kato; Masayoshi Shichiri; Fumiaki Marumo; Yasunobu Hirata
Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells.
Endocrinology 1997;138(6):2615-20.
1997: H Ikenouchi; Kenji Kangawa; Hisayuki Matsuo; Yasunobu Hirata
Negative inotropic effect of adrenomedullin in isolated adult rabbit cardiac ventricular myocytes.
Circulation 1997;95(9):2318-24.
1997: Atsuo Goto; Koei Yamada; H Nagoshi; Akihiro Ishiyama; Mutsuhiko Minami; Yoshio Uehara; Keiichiro Atarashi; Yasunobu Hirata; Kenjiro Kimura; Masao Omata
Relation of 24-h ambulatory blood pressure with plasma potassium in essential hypertension.
American journal of hypertension 1997;10(3):337-40.
1997: Yasunobu Hirata; Hiroshi Hayakawa; Masao Kakoki; Arinobu Tojo; Etsu Suzuki; Daisuke Nagata; Kenjiro Kimura; Atsuo Goto; Kazuya Kikuchi; Tetsuo Nagano; Masaaki Hirobe; Masao Omata
Receptor subtype for vasopressin-induced release of nitric oxide from rat kidney.
Hypertension 1997;29(1 Pt 1):58-64.
1996: Atsuo Goto; Koei Yamada; H Hazama; Yoshio Uehara; K Atarashi; Yasunobu Hirata; K Kimura; Masao Omata
Ouabainlike compound in hypertension associated with ectopic corticotropin syndrome.
Hypertension 1996;28(3):421-5.
1996: H Iwasaki; Yasunobu Hirata; M Iwashina; K Sato; Fumiaki Marumo
Specific binding sites for proadrenomedullin N-terminal 20 peptide (PAMP) in the rat.
Endocrinology 1996;137(7):3045-50.
1996: K Kimura; Naoe Suzuki; Shigeyoshi Ohba; Ryozo Nagai; J Hiroi; Naobumi Mise; Arinobu Tojo; A Nagaoka; Yasunobu Hirata; Atsuo Goto; Y Yazaki; Masao Omata
Hypertensive glomerular damage as revealed by the expression of alpha-smooth muscle actin and non-muscle myosin.
Kidney international. Supplement 1996;55():S169-72.
1996: Arinobu Tojo; N Kobayashi; K Kimura; Yasunobu Hirata; H Matsuoka; S Yagi; Masao Omata
Effects of antihypertensive drugs on nitric oxide synthase activity in rat kidney.
Kidney international. Supplement 1996;55():S138-40.
1996: M Iwashina; Yasunobu Hirata; T Imai; K Sato; Fumiaki Marumo
Molecular cloning of endothelial, inducible nitric oxide synthase gene from rat aortic endothelial cell.
European journal of biochemistry / FEBS 1996;237(3):668-73.
1996: Yasunobu Hirata; Hiroshi Hayakawa; Masao Kakoki; Arinobu Tojo; Etsu Suzuki; K Kimura; Atsuo Goto; K Kikuchi; Tetsuo Nagano; Masaaki Hirobe; Masao Omata
Nitric oxide release from kidneys of hypertensive rats treated with imidapril.
Hypertension 1996;27(3 Pt 2):672-8.
1996: Yasunobu Hirata
Endothelin peptides.
Current opinion in nephrology and hypertension 1996;5(1):12-5.
1995: H Fujisaki; Hiroshi Ito; Yasunobu Hirata; M Tanaka; M Hata; M Lin; Susumu Adachi; H Akimoto; Fumiaki Marumo; Michiaki Hiroe
Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression.
The Journal of clinical investigation 1995;96(2):1059-65.
1995: A Matsumoto; K Ogura; Yasunobu Hirata; Masao Kakoki; F Watanabe; K Takenaka; Y Shiratori; Shin-ichi Momomura; Masao Omata
Increased nitric oxide in the exhaled air of patients with decompensated liver cirrhosis.
Annals of internal medicine 1995;123(2):110-3.
1995: T Imai; Yasunobu Hirata; M Iwashina; Fumiaki Marumo
Hormonal regulation of rat adrenomedullin gene in vasculature.
Endocrinology 1995;136(4):1544-8.
1995: Yasunobu Hirata; Y Suzuki; H Hayakawa; E Suzuki; K Kimura; Atsuo Goto; K Kangawa; H Matsuo; Masao Omata
Participation of endogenous atrial natriuretic peptide in the regulation of urinary protein excretion in experimental diabetic rats.
Clinical science (London, England : 1979) 1995;88(4):413-9.
1995: Yasunobu Hirata; Hiroshi Hayakawa; Y Suzuki; Etsu Suzuki; H Ikenouchi; Osami Kohmoto; K Kimura; Kazuo Kitamura; T Eto; Kenji Kangawa
Mechanisms of adrenomedullin-induced vasodilation in the rat kidney.
Hypertension 1995;25(4 Pt 2):790-5.
1995: Masayoshi Shichiri; Yasunobu Hirata
[Endothelin].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Su Pt 2():749-51.
1995: Yasunobu Hirata; Hiroshi Hayakawa; Etsu Suzuki; K Kimura; K Kikuchi; Tetsuo Nagano; Masaaki Hirobe; Masao Omata
Direct measurements of endothelium-derived nitric oxide release by stimulation of endothelin receptors in rat kidney and its alteration in salt-induced hypertension.
Circulation 1995;91(4):1229-35.
1995: S Saito; Yasunobu Hirata; T Imai; Fumiaki Marumo
Autocrine regulation of the endothelin-1 gene in rat endothelial cells.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S84-7.
1995: S Eguchi; Yasunobu Hirata; T Imai; Fumiaki Marumo
Endothelin-1 as an autocrine growth factor for endothelial cells.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S279-83.
1995: Susumu Adachi; Hiroshi Ito; Y Ohta; M Tanaka; Shigeru Ishiyama; M Nagata; Tetsuya Toyozaki; Yasunobu Hirata; Fumiaki Marumo; Michiaki Hiroe
Distribution of mRNAs for natriuretic peptides in RV hypertrophy after pulmonary arterial banding.
The American journal of physiology 1995;268(1 Pt 2):H162-9.
1995: M Tsujino; Yasunobu Hirata; S Eguchi; T Watanabe; F Chatani; Fumiaki Marumo
Nonselective ETA/ETB receptor antagonist blocks proliferation of rat vascular smooth muscle cells after balloon angioplasty.
Life sciences 1995;56(25):PL449-54.
1995: Hiroshi Hayakawa; Yasunobu Hirata; Etsu Suzuki; Masao Kakoki; K Kikuchi; Tetsuo Nagano; Masaaki Hirobe; Masao Omata
Endothelium-derived relaxing factors in the kidney of spontaneously hypertensive rats.
Life sciences 1995;56(21):PL401-8.
1995: K Sato; Yasunobu Hirata; T Imai; M Iwashina; Fumiaki Marumo
Characterization of immunoreactive adrenomedullin in human plasma and urine.
Life sciences 1995;57(2):189-94.
1994: S Eguchi; Yasunobu Hirata; H Iwasaki; K Sato; T X Watanabe; T Inui; K Nakajima; S Sakakibara; Fumiaki Marumo
Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells.
Endocrinology 1994;135(6):2454-8.
1994: K Kanno; Yasunobu Hirata; T Imai; M Iwashina; Fumiaki Marumo
Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells.
The American journal of physiology 1994;267(6 Pt 2):H2318-24.
1994: Koichiro Kinugawa; T Takahashi; Osami Kohmoto; Atsushi Yao; T Aoyagi; Shin-ichi Momomura; Yasunobu Hirata; Takashi Serizawa
Nitric oxide-mediated effects of interleukin-6 on [Ca2+]i and cell contraction in cultured chick ventricular myocytes.
Circulation research 1994;75(2):285-95.
1994: M Tsujino; Yasunobu Hirata; T Imai; K Kanno; S Eguchi; Hiroshi Ito; Fumiaki Marumo
Induction of nitric oxide synthase gene by interleukin-1 beta in cultured rat cardiocytes.
Circulation 1994;90(1):375-83.
1994: S Eguchi; Yasunobu Hirata; T Imai; Fumiaki Marumo
C-type natriuretic peptide upregulates vascular endothelin type B receptors.
Hypertension 1994;23(6 Pt 2):936-40.
1994: Hiroshi Hayakawa; Yasunobu Hirata; Etsu Suzuki; K Kimura; K Kikuchi; Tetsuo Nagano; Masaaki Hirobe; Masao Omata
Long-term administration of L-arginine improves nitric oxide release from kidney in deoxycorticosterone acetate-salt hypertensive rats.
Hypertension 1994;23(6 Pt 1):752-6.
1994: Hiroshi Ito; Michiaki Hiroe; Yasunobu Hirata; H Fujisaki; Susumu Adachi; H Akimoto; Y Ohta; Fumiaki Marumo
Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload.
Circulation 1994;89(5):2198-203.
1994: Yasunobu Hirata; Y Suzuki; Etsu Suzuki; Hiroshi Hayakawa; K Kimura; Atsuo Goto; Masao Omata; N Minamino; Kenji Kangawa; Hisayuki Matsuo
Mechanisms underlying the augmented responses of deoxycorticosterone acetate-salt hypertensive rats to neutral endopeptidase inhibitors.
Journal of hypertension 1994;12(4):367-74.
1994: S Eguchi; Yasunobu Hirata; H Kano; K Sato; Y Watanabe; T X Watanabe; K Nakajima; S Sakakibara; Fumiaki Marumo
Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells.
FEBS letters 1994;340(3):226-30.
1994: Yasunobu Hirata; Hiroshi Hayakawa; Etsu Suzuki; Masao Omata
Does endothelin work as an intrarenal mechanism to alter pressure natriuresis in spontaneously hypertensive rats?
Journal of hypertension 1994;12(3):251-7.
1994: Yasunobu Hirata; Etsu Suzuki; Hiroshi Hayakawa; H Matsuoka; T Sugimoto; Kenji Kangawa; Hisayuki Matsuo
Mechanisms of the natriuretic effects of neutral endopeptidase inhibition in Dahl salt-sensitive and salt-resistant rats.
Journal of cardiovascular pharmacology 1994;23(2):283-90.
1994: T Imai; Yasunobu Hirata; K Kanno; Fumiaki Marumo
Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells.
The Journal of clinical investigation 1994;93(2):543-9.
1994: S Eguchi; Yasunobu Hirata; T Imai; K Kanno; Fumiaki Marumo
Phenotypic change of endothelin receptor subtype in cultured rat vascular smooth muscle cells.
Endocrinology 1994;134(1):222-8.
1994: K Kimura; Arinobu Tojo; Yasunobu Hirata; Hiroshi Hayakawa; Atsuo Goto; Masao Omata
Effects of a calcium antagonist and an angiotensin II receptor antagonist on rat renal arterioles.
Blood pressure. Supplement 1994;5():71-4.
1993: T Emori; Yasunobu Hirata; T Imai; S Eguchi; K Kanno; Fumiaki Marumo
Cellular mechanism of natriuretic peptides-induced inhibition of endothelin-1 biosynthesis in rat endothelial cells.
Endocrinology 1993;133(6):2474-80.
1993: K Kikuchi; Tetsuo Nagano; Hiroshi Hayakawa; Yasunobu Hirata; Masaaki Hirobe
Real time measurement of nitric oxide produced ex vivo by luminol-H2O2 chemiluminescence method.
The Journal of biological chemistry 1993;268(31):23106-10.
1993: K Kimura; Arinobu Tojo; Yasunobu Hirata; H Matsuoka; T Sugimoto
Morphometric analysis of renal arterioles in subtotally nephrectomized rats.
The Journal of laboratory and clinical medicine 1993;122(3):273-83.
1993: Osami Kohmoto; H Ikenouchi; Yasunobu Hirata; Shin-ichi Momomura; Takashi Serizawa; William H Barry
Variable effects of endothelin-1 on [Ca2+]i transients, pHi, and contraction in ventricular myocytes.
The American journal of physiology 1993;265(3 Pt 2):H793-800.
1993: K Ohta; Yasunobu Hirata; T Imai; Fumiaki Marumo
Interleukin-1 beta induces nitric oxide production by a mouse pituitary tumour cell line (AtT20/D16).
The Journal of endocrinology 1993;138(3):429-35.
1993: K Kanno; Yasunobu Hirata; M Tsujino; T Imai; Masayoshi Shichiri; Hiroshi Ito; Fumiaki Marumo
Up-regulation of ETB receptor subtype mRNA by angiotensin II in rat cardiomyocytes.
Biochemical and biophysical research communications 1993;194(3):1282-7.
1993: K Kikuchi; Tetsuo Nagano; Hiroshi Hayakawa; Yasunobu Hirata; Masaaki Hirobe
Detection of nitric oxide production from a perfused organ by a luminol-H2O2 system.
Analytical chemistry 1993;65(13):1794-9.
1993: Hiroshi Ito; Yasunobu Hirata; Susumu Adachi; M Tanaka; M Tsujino; A Koike; Akihiko Nogami; F Murumo; Michiaki Hiroe
Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes.
The Journal of clinical investigation 1993;92(1):398-403.
1993: K Kanno; Yasunobu Hirata; T Imai; Fumiaki Marumo
Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells.
Hypertension 1993;22(1):34-9.
1993: Yasunobu Hirata
[Physiological and pathophysiological role of endothelin-endothelin receptors system in cardiovascular system].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(6):1540-7.
1993: Hiroshi Hayakawa; Yasunobu Hirata; Etsu Suzuki; T Sugimoto; H Matsuoka; K Kikuchi; Tetsuo Nagano; Masaaki Hirobe; T Sugimoto
Mechanisms for altered endothelium-dependent vasorelaxation in isolated kidneys from experimental hypertensive rats.
The American journal of physiology 1993;264(5 Pt 2):H1535-41.
1993: Yasunobu Hirata
[Natriuretic peptide family].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(5):1156-64.
1993: T Aoyagi; Yasunobu Hirata
[Progress in management for heart failure: diuretics].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(5):1281-6.
1993: Hiroshi Ito; Michiaki Hiroe; Yasunobu Hirata; M Tsujino; Susumu Adachi; Masayoshi Shichiri; A Koike; Akihiko Nogami; Fumiaki Marumo
Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes.
Circulation 1993;87(5):1715-21.
1993: Etsu Suzuki; Yasunobu Hirata; Hiroshi Hayakawa; Masao Omata; M Kojima; Kenji Kangawa; N Minamino; Hisayuki Matsuo
Evidence for C-type natriuretic peptide production in the rat kidney.
Biochemical and biophysical research communications 1993;192(2):532-8.
1993: T Imai; Yasunobu Hirata; T Emori; Fumiaki Marumo
Heparin has an inhibitory effect on endothelin-1 synthesis and release by endothelial cells.
Hypertension 1993;21(3):353-8.
1993: Shinichi Uchida; Sei Sasaki; T Furukawa; M Hiraoka; T Imai; Yasunobu Hirata; Fumiaki Marumo
Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla.
The Journal of biological chemistry 1993;268(6):3821-4.
1993: K Fushimi; Shinichi Uchida; Y Hara; Yasunobu Hirata; Fumiaki Marumo; Sei Sasaki
Cloning and expression of apical membrane water channel of rat kidney collecting tubule.
Nature 1993;361(6412):549-52.
1993: Yasunobu Hirata; H Matsuoka; Etsu Suzuki; Hiroshi Hayakawa; T Sugimoto; Y Matsuda; Y Morishita; Kenji Kangawa; N Minamino; Hisayuki Matsuo
Role of endogenous atrial natriuretic peptide in DOCA-salt hypertensive rats. Effects of a novel nonpeptide antagonist for atrial natriuretic peptide receptor.
Circulation 1993;87(2):554-61.
1993: S Eguchi; Yasunobu Hirata; T Imai; Fumiaki Marumo
Endothelin receptor subtypes are coupled to adenylate cyclase via different guanyl nucleotide-binding proteins in vasculature.
Endocrinology 1993;132(2):524-9.
1993: K Ohta; Yasunobu Hirata
[Ectopic hormone-producing tumor].
Nihon rinsho. Japanese journal of clinical medicine 1993;51 Suppl():234-40.
1993: Yasunobu Hirata
[Recent advance in cardiovascular regulation research].
Japanese circulation journal 1993;57 Suppl 4():1131-5.
1993: T Imai; Yasunobu Hirata; Fumiaki Marumo
Heparin inhibits endothelin-1 and proto-oncogene c-fos gene expression in cultured bovine endothelial cells.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S49-52.
1993: S Eguchi; Yasunobu Hirata; Fumiaki Marumo
Endothelin subtype B receptors are coupled to adenylate cyclase via inhibitory G protein in cultured bovine endothelial cells.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S161-3.
1992: T Emori; Yasunobu Hirata; T Imai; K Ohta; K Kanno; S Eguchi; Fumiaki Marumo
Cellular mechanism of thrombin on endothelin-1 biosynthesis and release in bovine endothelial cell.
Biochemical pharmacology 1992;44(12):2409-11.
1992: Etsu Suzuki; Yasunobu Hirata; Osami Kohmoto; T Sugimoto; Hiroshi Hayakawa; H Matsuoka; T Sugimoto; M Kojima; K Kangawa; N Minamino
Cellular mechanisms for synthesis and secretion of atrial natriuretic peptide and brain natriuretic peptide in cultured rat atrial cells.
Circulation research 1992;71(5):1039-48.
1992: Yasunobu Hirata
[Vascular endothelium and hypertension with emphasis on NO and endothelins].
Kokyu to junkan. Respiration & circulation 1992;40(11):1075-84.
1992: T Ishimitsu; Yasunobu Hirata; H Matsuoka; M Ishii; T Sugimoto; Kenji Kangawa; H Matsuo
In vivo and in vitro effects of atrial natriuretic peptide on renin release.
Clinical and experimental pharmacology & physiology 1992;19(10):711-6.
1992: K Kanno; Yasunobu Hirata; T Emori; K Ohta; S Eguchi; T Imai; Fumiaki Marumo
L-arginine infusion induces hypotension and diuresis/natriuresis with concomitant increased urinary excretion of nitrite/nitrate and cyclic GMP in humans.
Clinical and experimental pharmacology & physiology 1992;19(9):619-25.
1992: T Imai; Yasunobu Hirata; T Emori; M Yanagisawa; T Masaki; Fumiaki Marumo
Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells.
Hypertension 1992;19(6 Pt 2):753-7.
1992: Yasunobu Hirata; Etsu Suzuki; Hiroshi Hayakawa; H Matsuoka; T Sugimoto; M Kojima; Kenji Kangawa; Hisayuki Matsuo
Role of endogenous ANP in sodium excretion in rats with experimental pulmonary hypertension.
The American journal of physiology 1992;262(6 Pt 2):H1684-9.
1992: H Matsui; Osami Kohmoto; Yasunobu Hirata; T Serizawa
Effects of a nonpeptide vasopressin antagonist (OPC-21268) on cytosolic Ca2+ concentration in vascular and cardiac myocytes.
Hypertension 1992;19(6 Pt 2):730-3.
1992: S Eguchi; Yasunobu Hirata; M Ihara; M Yano; Fumiaki Marumo
A novel ETA antagonist (BQ-123) inhibits endothelin-1-induced phosphoinositide breakdown and DNA synthesis in rat vascular smooth muscle cells.
FEBS letters 1992;302(3):243-6.
1992: S Eguchi; Yasunobu Hirata; T Imai; K Kanno; T Akiba; A Sakamoto; M Yanagisawa; T Masaki; Fumiaki Marumo
Endothelin receptors in human parathyroid gland.
Biochemical and biophysical research communications 1992;184(3):1448-55.
1992: Yasunobu Hirata; T Sugimoto
[Etiological and physiopathological significance of atrial natriuretic peptide activity in essential hypertension].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():347-52.
1992: Etsu Suzuki; Yasunobu Hirata; H Matsuoka; T Sugimoto; Hiroshi Hayakawa; T Sugimoto; Kenji Kangawa; N Minamino; Hisayuki Matsuo
Characterization of atrial natriuretic peptide in urine from rats treated with a neutral endopeptidase inhibitor.
Biochemical and biophysical research communications 1992;182(3):1270-6.
1992: T Imai; Yasunobu Hirata; S Eguchi; K Kanno; K Ohta; T Emori; A Sakamoto; M Yanagisawa; T Masaki; Fumiaki Marumo
Concomitant expression of receptor subtype and isopeptide of endothelin by human adrenal gland.
Biochemical and biophysical research communications 1992;182(3):1115-21.
1992: S Eguchi; Yasunobu Hirata; T Imai; K Kanno; K Ohta; T Emori; Fumiaki Marumo
Effects of three distinct natriuretic peptides on receptor binding and guanylate cyclase activities in rat glioma cells.
European journal of pharmacology 1992;225(1):79-82.
1992: Masahiko Ichioka; Yasunobu Hirata; Naohiko Inase; N Tojo; M Yoshizawa; M Chida; I Miyazato; S Taniai; Fumiaki Marumo
Changes of circulating atrial natriuretic peptide and antidiuretic hormone in obstructive sleep apnea syndrome.
Respiration; international review of thoracic diseases 1992;59(3):164-8.
1992: Yasunobu Hirata
[Atrial natriuretic peptide in chronic renal failure].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():623-31.
1992: Hiroshi Ito; Michiaki Hiroe; Yasunobu Hirata; Susumu Adachi; M Tujino; Fumiaki Marumo
[Endothelin-1 as an autocrine factor in hypertrophy of cardiomyocytes].
Japanese circulation journal 1992;56 Suppl 5():1314-8.
1991: Etsu Suzuki; Yasunobu Hirata; H Matsuoka; T Sugimoto; Hiroshi Hayakawa; Wee Soo Shin; T Toyooka; T Sugimoto
Effects of atrial natriuretic peptide on endothelin-induced vasoconstriction and intracellular calcium mobilization.
Journal of hypertension 1991;9(10):927-34.
1991: T Emori; Yasunobu Hirata; K Ohta; K Kanno; S Eguchi; T Imai; Masayoshi Shichiri; Fumiaki Marumo
Cellular mechanism of endothelin-1 release by angiotensin and vasopressin.
Hypertension 1991;18(2):165-70.
1991: H Matsuoka; K Fukui; Y Dan; T Ishimitsu; Yasunobu Hirata; K Kimura; T Sugimoto; M Ishii; Kenji Kangawa; H Matsuo
Atrial natriuretic peptide inhibits the aldosterone response to metoclopramide in patients with glomerular disease and essential hypertension.
Clinical and experimental pharmacology & physiology 1991;18(8):557-62.
1991: T Ishimitsu; Yoshio Uehara; J Iwai; T Sugimoto; Yasunobu Hirata; H matsuoka; T Sugimoto
Vascular eicosanoid production in experimental hypertensive rats with different mechanisms.
Prostaglandins, leukotrienes, and essential fatty acids 1991;43(3):179-84.
1991: M Shichiri; N Miyasaka; Yasunobu Hirata; K Ando; Fumiaki Marumo
Appearance of beta-human atrial natriuretic peptide in collagen disease.
The Journal of endocrinology 1991;130(1):159-61.
1991: Kunihiko Mabuchi; Hiroshi Hayakawa; Yasunobu Hirata; M Iizuka; Kou Imachi; Tsuneo Chinzei; H Nozawa; Yusuke Abe; T Yonezawa; M Suzukawa
Suppression of the natriuretic effects of exogenous atrial natriuretic peptide in animals with total artificial hearts.
ASAIO transactions / American Society for Artificial Internal Organs 1991;37(3):M214-6.
1991: Yasunobu Hirata; H Matsuoka; Hiroshi Hayakawa; T Sugimoto; Etsu Suzuki; T Sugimoto; Kenji Kangawa; Hisayuki Matsuo
Role of endogenous atrial natriuretic peptide in regulating sodium excretion in spontaneously hypertensive rats. Effects of neutral endopeptidase inhibition.
Hypertension 1991;17(6 Pt 2):1025-32.
1991: M Shichiri; Yasunobu Hirata; T Nakajima; K Ando; T Imai; M Yanagisawa; T Masaki; Fumiaki Marumo
Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines.
The Journal of clinical investigation 1991;87(5):1867-71.
1991: K Ohta; Yasunobu Hirata; Masayoshi Shichiri; K Kanno; T Emori; Kimio Tomita; Fumiaki Marumo
Urinary excretion of endothelin-1 in normal subjects and patients with renal disease.
Kidney international 1991;39(2):307-11.
1991: Yasunobu Hirata; M Ishii; K Fukui; H Hayakawa; E Suzuki; T Sugimoto; K Kimura; H Matsuoka; T Sugimoto
Differential effects of atrial natriuretic peptide and dopamine on urinary protein excretion in chronic glomerulonephritis.
Clinical science (London, England : 1979) 1991;80(2):131-6.
1991: Teruhiko Toyo-Oka; Tadanori Aizawa; N Suzuki; Yasunobu Hirata; T Miyauchi; Wee Soo Shin; M Yanagisawa; T Masaki; T Sugimoto
Increased plasma level of endothelin-1 and coronary spasm induction in patients with vasospastic angina pectoris.
Circulation 1991;83(2):476-83.
1991: T Emori; Yasunobu Hirata; K Kanno; K Ohta; S Eguchi; T Imai; Masayoshi Shichiri; Fumiaki Marumo
Endothelin-3 stimulates production of endothelium-derived nitric oxide via phosphoinositide breakdown.
Biochemical and biophysical research communications 1991;174(1):228-35.
1991: K Ando; Yasunobu Hirata; Y Takei; M Kawakami; Fumiaki Marumo
Endothelin-1-like immunoreactivity in human urine.
Nephron 1991;57(1):36-9.
1991: Yasunobu Hirata; M Ishii; K Fukui; H Hayakawa; E Suzuki; T Sugimoto; K Kimura; H Matsuoka; T Sugimoto
Effects of atrial natriuretic peptide on urinary protein excretion in mesangial proliferative glomerulonephritis.
Nephron 1991;58(1):58-61.
1991: Masayoshi Shichiri; Yasunobu Hirata; Fumiaki Marumo
Endothelin-1 as an autocrine/paracrine factor for human tumor cell lines.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S76-8.
1991: K Kanno; Yasunobu Hirata; Masayoshi Shichiri; Fumiaki Marumo
Plasma endothelin-1 levels in patients with diabetes mellitus with or without vascular complication.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S475-6.
1991: K Ando; Yasunobu Hirata; K Togashi; M Kawakami; Fumiaki Marumo
Endothelin-1- and endothelin-3-like immunoreactivity in human cerebrospinal fluid.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S434-6.
1991: S Ota; Yasunobu Hirata; T Sugimoto; Osami Kohmoto; Y Hata; K Yoshiura; R Nakada; A Terano; T Sugimoto
Endothelin-1 secretion from cultured rabbit gastric epithelial cells.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S406-7.
1991: Yasunobu Hirata; H Matsuoka; K Kimura; T Sugimoto; Hiroshi Hayakawa; Etsu Suzuki; T Sugimoto
Role of endothelium-derived relaxing factor in endothelin-induced renal vasoconstriction.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S169-71.
1991: T Emori; Yasunobu Hirata; Fumiaki Marumo
Endothelin-3 stimulates prostacyclin production in cultured bovine endothelial cells.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S140-2.
1990: K Kimura; Yasunobu Hirata; S Nanba; Arinobu Tojo; H Matsuoka; T Sugimoto
Effects of atrial natriuretic peptide on renal arterioles: morphometric analysis using microvascular casts.
The American journal of physiology 1990;259(6 Pt 2):F936-44.
1990: Yasunobu Hirata; K Fukui; H Hayakawa; E Suzuki; T Sugimoto; K Kimura; H Matsuoka; T Sugimoto
Renal effects of atrial natriuretic peptide during dopamine infusion.
American journal of hypertension 1990;3(11):866-9.
1990: Yasunobu Hirata; K Fukui; Hiroshi Hayakawa; S Namba; T Ishimitsu; T Sugimoto; K Kimura; H Matsuoka; T Sugimoto
Nephrogenous cyclic GMP production during NaCl loading and ANP infusion.
Japanese heart journal 1990;31(6):809-16.
1990: H Sakamoto; Sei Sasaki; Yasunobu Hirata; T Imai; K Ando; T Ida; T Sakurai; M Yanagisawa; T Masaki; Fumiaki Marumo
Production of endothelin-1 by rat cultured mesangial cells.
Biochemical and biophysical research communications 1990;169(2):462-8.
1990: K Ohta; Yasunobu Hirata; T Imai; K Kanno; T Emori; Masayoshi Shichiri; Fumiaki Marumo
Cytokine-induced release of endothelin-1 from porcine renal epithelial cell line.
Biochemical and biophysical research communications 1990;169(2):578-84.
1990: Arinobu Tojo; S Nanba; K Kimura; Yasunobu Hirata; H Matsuoka; T Sugimoto; N Watanabe; A Ohkubo
Factitious proteinuria in a young girl.
Clinical nephrology 1990;33(6):299-302.
1990: K Ando; Yasunobu Hirata; T Emori; M Shichiri; T Kurosawa; K Sato; F Marumo
Circulating forms of human atrial natriuretic peptide in patients with congestive heart failure.
The Journal of clinical endocrinology and metabolism 1990;70(6):1603-7.
1990: Yasunobu Hirata; T Koide; S Murao; H Matsuoka; M Ishii; T Sugimoto
Factors participating in blood pressure elevation after discharge from the hospital in patients with essential hypertension.
American journal of hypertension 1990;3(5 Pt 1):397-9.
1990: Masayoshi Shichiri; Yasunobu Hirata; K Ando; T Emori; K Ohta; S Kimoto; M Ogura; A Inoue; Fumiaki Marumo
Plasma endothelin levels in hypertension and chronic renal failure.
Hypertension 1990;15(5):493-6.
1990: T Emori; Yasunobu Hirata; Fumiaki Marumo
Specific receptors for endothelin-3 in cultured bovine endothelial cells and its cellular mechanism of action.
FEBS letters 1990;263(2):261-4.
1990: K Kimura; G Drozdova; Yasunobu Hirata; H Matsuoka; M Ishii; T Sugimoto; K Kangawa; H Matsuo
Effects of chronic administration of atrial natriuretic polypeptide on glomerular lesions in spontaneously hypertensive rats.
Japanese heart journal 1990;31(2):227-36.
1990: Yasunobu Hirata; T Matsunaga; K Ando; T Furukawa; H Tsukagoshi; Fumiaki Marumo
Presence of endothelin-1-like immunoreactivity in human cerebrospinal fluid.
Biochemical and biophysical research communications 1990;166(3):1274-8.
1990: Yasunobu Hirata; K Kanno; T X Watanabe; S Kumagaye; K Nakajima; T Kimura; S Sakakibara; Fumiaki Marumo
Receptor binding and vasoconstrictor activity of big endothelin.
European journal of pharmacology 1990;176(2):225-8.
1990: Yasunobu Hirata
[Assay of epidermal growth factor in body fluids and the clinical significance].
Nihon rinsho. Japanese journal of clinical medicine 1990;48 Suppl():145-50.
1990: Yasunobu Hirata; M Ishii; K Fukui; T Sugimoto; Keiichiro Atarashi; H Matsuoka; M Iizuka; T Sugimoto; K Sakamoto; H Kanai
The extrarenal effects of atrial natriuretic peptide on body fluid distribution.
American journal of hypertension 1990;3(2):140-7.
1990: M Shichiri; H Itoh; H Iwamoto; Yasunobu Hirata; Fumiaki Marumo
Renal tubular hypouricemia: evidence for defect of both secretion and reabsorption.
Nephron 1990;56(4):421-6.
1989: M Ishi; Yasunobu Hirata; T Sugimoto; H Matsuoka; K Kimura; T Ishimitsu; K Fukui; T Sugimoto; Y Kurosawa; H Kiyose
Effect of alpha-human atrial natriuretic peptide on proteinuria in patients with primary glomerular diseases.
Clinical science (London, England : 1979) 1989;77(6):643-50.
1989: Yasunobu Hirata; H Matsuoka; K Kimura; K Fukui; Hiroshi Hayakawa; Etsu Suzuki; T Sugimoto; T Sugimoto; M Yanagisawa; T Masaki
Renal vasoconstriction by the endothelial cell-derived peptide endothelin in spontaneously hypertensive rats.
Circulation research 1989;65(5):1370-9.
1989: Masayoshi Shichiri; Yasunobu Hirata; K Kanno; K Ohta; T Emori; Fumiaki Marumo
Effect of endothelin-1 on release of arginine-vasopressin from perifused rat hypothalamus.
Biochemical and biophysical research communications 1989;163(3):1332-7.
1989: Yasunobu Hirata; Y Takagi; Y Fukuda; Fumiaki Marumo
Endothelin is a potent mitogen for rat vascular smooth muscle cells.
Atherosclerosis 1989;78(2-3):225-8.
1989: T Emori; Yasunobu Hirata; K Ohta; Masayoshi Shichiri; K Shimokado; Fumiaki Marumo
Concomitant secretion of big endothelin and its C-terminal fragment from human and bovine endothelial cells.
Biochemical and biophysical research communications 1989;162(1):217-23.
1989: Yasunobu Hirata; H Yoshimi; Fumiaki Marumo; T X Watanabe; S Kumagaye; K Nakajima; T Kimura; S Sakakibara
Interaction of synthetic sarafotoxin with rat vascular endothelin receptors.
Biochemical and biophysical research communications 1989;162(1):441-7.
1989: H Ikenouchi; H Sato; Yasunobu Hirata; M Iizuka; Takashi Serizawa; T Sugimoto
Lack of venodilative activity of alpha human atrial natriuretic polypeptide in patients with congestive heart failure.
Japanese heart journal 1989;30(4):443-57.
1989: Yasunobu Hirata; T Emori; K Ohta; Masayoshi Shichiri; Fumiaki Marumo
Vasoconstrictor-induced heterologous down-regulation of vascular atrial natriuretic peptide receptor.
European journal of pharmacology 1989;164(3):603-6.
1989: Yasunobu Hirata; Y Fukuda; H Yoshimi; T Emori; Masayoshi Shichiri; Fumiaki Marumo
Specific receptor for endothelin in cultured rat cardiocytes.
Biochemical and biophysical research communications 1989;160(3):1438-44.
1989: Yasunobu Hirata; M Ishii; K Fukui; Hiroshi Hayakawa; T Sugimoto; H Matsuoka; T Sugimoto; Kenji Kangawa; Hisayuki Matsuo
Interaction between sympathetic nerve activity and atrial natriuretic peptide with respect to the effects on renal hemodynamics in patients with cardiovascular diseases.
Japanese circulation journal 1989;53(5):446-52.
1989: Yasunobu Hirata; H Yoshimi; T Emori; M Shichiri; Fumiaki Marumo; T X Watanabe; S Kumagaye; K Nakajima; T Kimura; S Sakakibara
Receptor binding activity and cytosolic free calcium response by synthetic endothelin analogs in cultured rat vascular smooth muscle cells.
Biochemical and biophysical research communications 1989;160(1):228-34.
1989: S Takayama-Hasumi; Kazuyuki Tobe; K Momomura; O Koshio; Y Tashiro-Hashimoto; Yasuo Akanuma; Yasunobu Hirata; F Takaku; M Kasuga
Autoantibodies to the insulin receptor (B-10) can stimulate tyrosine phosphorylation of the beta-subunit of the insulin receptor and a 185,000 molecular weight protein in rat hepatoma cells.
The Journal of clinical endocrinology and metabolism 1989;68(4):787-95.
1989: K Ando; Yasunobu Hirata; Masayoshi Shichiri; T Emori; Fumiaki Marumo
Presence of immunoreactive endothelin in human plasma.
FEBS letters 1989;245(1-2):164-6.
1989: Yasunobu Hirata; K Fukui; Y Dan; H Matsuoka; T Sugimoto; M Ishii
Renal and hormonal effects of alpha 1-adrenoceptor blockade by bunazosin in essential hypertension.
European journal of clinical pharmacology 1989;36(6):575-8.
1989: Yasunobu Hirata; K Fukui; T Sugimoto; H Matsuoka; M Ishii; T Sugimoto; A Miyata; K Kangawa; H Matsuo
The effects of atrial pacing and ballooning on the plasma concentration of atrial natriuretic peptide in anesthetized dogs with or without vagotomy.
Clinical and experimental hypertension. Part A, Theory and practice 1989;11(1):89-101.
1989: K Kimura; S Nanba; Arinobu Tojo; Yasunobu Hirata; H Matsuoka; T Sugimoto
Variations in arterioles in spontaneously hypertensive rats. Morphometric analysis of afferent and efferent arterioles.
Virchows Archiv. A, Pathological anatomy and histopathology 1989;415(6):565-9.
1989: Yasunobu Hirata; M Ishii; K Fukui; Hiroshi Hayakawa; S Namba; Y Dan; T Ishimitsu; T Sugimoto; K Kimura; H Matsuoka
A possible physiological role of atrial natriuretic peptide in body fluid volume regulation.
Journal of cardiovascular pharmacology 1989;13 Suppl 6():S63-8.
1989: Yasunobu Hirata
Endothelin-1 receptors in cultured vascular smooth muscle cells and cardiocytes of rats.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S157-8.
1988: Yasunobu Hirata; M Ishii; H Matsuoka; T Sugimoto; M Iizuka; Takashi Serizawa; Osami Kohmoto; T Sugimoto; A Miyata; Kenji Kangawa
Plasma concentration of alpha-hANP and renal responses to alpha-hANP infusion in patients with congestive heart failure and those with chronic renal failure.
Japanese circulation journal 1988;52(12):1459-64.
1988: Yasunobu Hirata; M Ishii; T Sugimoto; H Matsuoka; K Fukui; T Sugimoto; M Yamakado; H Tagawa; A Miyata; Kenji Kangawa
Hormonal and renal effects of atrial natriuretic peptide in patients with secondary hypertension.
Circulation 1988;78(6):1401-10.
1988: Yasunobu Hirata; H Yoshimi; S Takaichi; M Yanagisawa; T Masaki
Binding and receptor down-regulation of a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells.
FEBS letters 1988;239(1):13-7.
1988: Takashi Serizawa; Osami Kohmoto; M Iizuka; Yasunobu Hirata; H Matsuoka; T Ohya; Y Kimura; H Sato; T Takahashi; M Masuo
Effects of alpha human atrial natriuretic polypeptide on the systemic hemodynamics and coronary circulation in patients with ischemic heart disease.
Japanese circulation journal 1988;52(10):1107-13.
1988: Takashi Serizawa; Yasunobu Hirata; Osami Kohmoto; M Iizuka; H Matsuoka; H Sato; T Takahashi; T Mochizuki; M Ishii; T Sugimoto
Acute hemodynamic effects of alpha human atrial natriuretic polypeptide in patients with congestive heart failure.
Japanese heart journal 1988;29(2):143-9.
1988: K Atarashi; H Matsuoka; M Takagi; K Yamada; Yasunobu Hirata; H Hayakawa; T Sugimoto
Effects of intracerebroventricular infusion of aldosterone on blood pressure and sodium and potassium concentrations in cerebral spinal fluid in rats.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10 Suppl 1():317-22.