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Bruce Hirayama

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Amy S Yu; Ana Diez Sampedro; Bruce A Hirayama; Sung-Cheng Huang; Vladimir Kepe; Jie Liu; Nagichettiar Satyamurthy; Gerald Timbol; Ernest M Wright; Jorge R Barrio
Regional distribution of SGLT activity in rat brain in vivo.
Xuan Jiang; Donald D F Loo; Bruce A Hirayama; Ernest M Wright
The importance of being aromatic: π interactions in sodium symporters.
Monica Sala-Rabanal; Jeff Abramson; Vincent Chaptal; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Bridging the gap between structure and kinetics of human SGLT1.

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2013: Amy S Yu; Ana Diez Sampedro; Bruce A Hirayama; Sung-Cheng Huang; Vladimir Kepe; Jie Liu; Nagichettiar Satyamurthy; Gerald Timbol; Ernest M Wright; Jorge R Barrio
Regional distribution of SGLT activity in rat brain in vivo.
American journal of physiology. Cell physiology 2013;304(3):C240-7.
2012: Xuan Jiang; Donald D F Loo; Bruce A Hirayama; Ernest M Wright
The importance of being aromatic: π interactions in sodium symporters.
Biochemistry 2012;51(47):9480-7.
2012: Monica Sala-Rabanal; Jeff Abramson; Vincent Chaptal; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Bridging the gap between structure and kinetics of human SGLT1.
American journal of physiology. Cell physiology 2012;302(9):C1293-305.
2011: Charles S Hummel; Chuan Lu; Donald D F Loo; Bruce A Hirayama; Andrew A Voss; Ernest M Wright
Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.
American journal of physiology. Cell physiology 2011;300(1):C14-21.
2010: Amy S Yu; Bruce A Hirayama; Gerald Timbol; Jie Liu; Ernest Basarah; Vladimir Kepe; Nagichettiar Satyamurthy; Sung-Cheng Huang; Ernest M Wright; Jorge R Barrio
Functional expression of SGLTs in rat brain.
American journal of physiology. Cell physiology 2010;299(6):C1277-84.
2008: Salem Faham; Akira Watanabe; Gabriel Mercado Besserer; Duilio Cascio; Alexandre Specht; Bruce A Hirayama; Ernest M Wright; Jeff Abramson
The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport.
Science (New York, N.Y.) 2008;321(5890):810-4.
2008: Monica Sala-Rabanal; Donald D F Loo; Bruce A Hirayama; Ernest M Wright
Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.
American journal of physiology. Renal physiology 2008;294(6):F1422-32.
2008: Donald D F Loo; Bruce A Hirayama; Monica Sala-Rabanal; Ernest M Wright
How drugs interact with transporters: SGLT1 as a model.
The Journal of membrane biology 2008;223(2):87-106.
2007: Bruce A Hirayama; Donald D F Loo; Ana Diez Sampedro; Daisy W Leung; Anne-Kristine Meinild; Mary Lai-Bing; Eric Turk; Ernest M Wright
Sodium-dependent reorganization of the sugar-binding site of SGLT1.
Biochemistry 2007;46(46):13391-406.
2007: Andrew A Voss; Ana Diez Sampedro; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Imino sugars are potent agonists of the human glucose sensor SGLT3.
Molecular pharmacology 2007;71(2):628-34.
2007: Ernest M Wright; Bruce A Hirayama; D F Loo
Active sugar transport in health and disease.
Journal of internal medicine 2007;261(1):32-43.
2006: Donald D F Loo; Bruce A Hirayama; Movses H Karakossian; Anne-Kristine Meinild; Ernest M Wright
Conformational dynamics of hSGLT1 during Na+/glucose cotransport.
The Journal of general physiology 2006;128(6):701-20.
2006: Monica Sala-Rabanal; Donald D F Loo; Bruce A Hirayama; Eric Turk; Ernest M Wright
Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1.
The Journal of physiology 2006;574(Pt 1):149-66.
2005: Donald D F Loo; Bruce A Hirayama; Albert Cha; Francisco Bezanilla; Ernest M Wright
Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter.
The Journal of general physiology 2005;125(1):13-36.
2004: Ernest M Wright; Donald D F Loo; Bruce A Hirayama; Eric Turk
Surprising versatility of Na+-glucose cotransporters: SLC5.
Physiology (Bethesda, Md.) 2004;19():370-6.
2004: Ana Diez Sampedro; Donald D F Loo; Ernest M Wright; Guido A Zampighi; Bruce A Hirayama
Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454.
Biochemistry 2004;43(41):13175-84.
2004: Marloes Veenstra; Seren Lanza; Bruce A Hirayama; Eric Turk; Ernest M Wright
Local conformational changes in the Vibrio Na+/galactose cotransporter.
Biochemistry 2004;43(12):3620-7.
2003: Ana Diez Sampedro; Bruce A Hirayama; Christina Osswald; Valentin Gorboulev; Katharina Baumgarten; Christopher Volk; Ernest M Wright; Hermann Koepsell
A glucose sensor hiding in a family of transporters.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11753-8.
2002: Anne-Kristine Meinild; Bruce A Hirayama; Ernest M Wright; Donald D F Loo
Fluorescence studies of ligand-induced conformational changes of the Na(+)/glucose cotransporter.
Biochemistry 2002;41(4):1250-8.
2001: Ana Diez Sampedro; Ernest M Wright; Bruce A Hirayama
Residue 457 controls sugar binding and transport in the Na(+)/glucose cotransporter.
The Journal of biological chemistry 2001;276(52):49188-94.
2001: Anne-Kristine Meinild; Donald D F Loo; Bruce A Hirayama; E Gallardo; Ernest M Wright
Evidence for the involvement of Ala 166 in coupling Na(+) to sugar transport through the human Na(+)/glucose cotransporter.
Biochemistry 2001;40(39):11897-904.
2001: Bruce A Hirayama; Ana Diez Sampedro; Ernest M Wright
Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters.
British journal of pharmacology 2001;134(3):484-95.
2001: Eain M Cornford; Marcia E Cornford; Ernest M Wright; David A Bruckner; Sharon Sampogna; Bruce A Hirayama
Human cerebral cysticercosis: immunolocalization of a sodium-dependent glucose cotransporter (SGLT) in larval and adult tapeworms.
The Journal of parasitology 2001;87(3):510-21.
2001: Ana Diez Sampedro; Sepehr Eskandari; Ernest M Wright; Bruce A Hirayama
Na+-to-sugar stoichiometry of SGLT3.
American journal of physiology. Renal physiology 2001;280(2):F278-82.
2000: Daisy W Leung; Donald D F Loo; Bruce A Hirayama; Thomas Zeuthen; Ernest M Wright
Urea transport by cotransporters.
The Journal of physiology 2000;528 Pt 2():251-7.
2000: Ana Diez Sampedro; M Pilar Lostao; Ernest M Wright; Bruce A Hirayama
Glycoside binding and translocation in Na(+)-dependent glucose cotransporters: comparison of SGLT1 and SGLT3.
The Journal of membrane biology 2000;176(2):111-7.
1999: M Panayotova-Heiermann; Daisy W Leung; Bruce A Hirayama; Ernest M Wright
Purification and functional reconstitution of a truncated human Na(+)/glucose cotransporter (SGLT1) expressed in E. coli.
FEBS letters 1999;459(3):386-90.
1999: Donald D F Loo; Bruce A Hirayama; Anne-Kristine Meinild; G Chandy; Thomas Zeuthen; Ernest M Wright
Passive water and ion transport by cotransporters.
The Journal of physiology 1999;518 ( Pt 1)():195-202.
1999: JT Lam; Martín G Martín; Eric Turk; Bruce A Hirayama; Nils U Bosshard; B Steinmann; Ernest M Wright
Missense mutations in SGLT1 cause glucose-galactose malabsorption by trafficking defects.
Biochimica et biophysica acta 1999;1453(2):297-303.
1998: Ernest M Wright; Donald D F Loo; M Panayotova-Heiermann; Bruce A Hirayama; Eric Turk; Sepehr Eskandari; JT Lam
Structure and function of the Na+/glucose cotransporter.
Acta physiologica Scandinavica. Supplementum 1998;643():257-64.
1998: Ana M Pajor; Bruce A Hirayama; Donald D F Loo
Sodium and lithium interactions with the Na+/Dicarboxylate cotransporter.
The Journal of biological chemistry 1998;273(30):18923-9.
1998: Donald D F Loo; Bruce A Hirayama; E M Gallardo; JT Lam; Eric Turk; Ernest M Wright
Conformational changes couple Na+ and glucose transport.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7789-94.
1997: Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Cation effects on protein conformation and transport in the Na+/glucose cotransporter.
The Journal of biological chemistry 1997;272(4):2110-5.
1996: Ernest M Wright; Donald Loo; Eric Turk; Bruce A Hirayama
Sodium cotransporters.
Current opinion in cell biology 1996;8(4):468-73.
1996: Bruce A Hirayama; M P Lostao; M Panayotova-Heiermann; Donald D F Loo; Eric Turk; Ernest M Wright
Kinetic and specificity differences between rat, human, and rabbit Na+-glucose cotransporters (SGLT-1).
The American journal of physiology 1996;270(6 Pt 1):G919-26.
1995: M P Lostao; Bruce A Hirayama; M Panayotova-Heiermann; Sharon Sampogna; D Bok; Ernest M Wright
Arginine-427 in the Na+/glucose cotransporter (SGLT1) is involved in trafficking to the plasma membrane.
FEBS letters 1995;377(2):181-4.
1994: M P Lostao; Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions.
The Journal of membrane biology 1994;142(2):161-70.
1994: Bruce A Hirayama; Donald D F Loo; Ernest M Wright
Protons drive sugar transport through the Na+/glucose cotransporter (SGLT1).
The Journal of biological chemistry 1994;269(34):21407-10.
1994: Bruce A Hirayama; A Hazama; D F Loo; Ernest M Wright; Glen E Kisby
Transport of cycasin by the intestinal Na+/glucose cotransporter.
Biochimica et biophysica acta 1994;1193(1):151-4.
1993: Ronaldo P Ferraris; J Hsiao; R Hernandez; Bruce A Hirayama
Site density of mouse intestinal glucose transporters declines with age.
The American journal of physiology 1993;264(2 Pt 1):G285-93.
1993: Ernest M Wright; Bruce A Hirayama; A Hazama; Donald D F Loo; stéphane supplisson; Eric Turk; K M Hager
The sodium/glucose cotransporter (SGLT1).
Society of General Physiologists series 1993;48():229-41.
1992: Ana M Pajor; Bruce A Hirayama; Ernest M Wright
Molecular biology approaches to comparative study of Na(+)-glucose cotransport.
The American journal of physiology 1992;263(3 Pt 2):R489-95.
1992: R P Ferraris; S A Villenas; Bruce A Hirayama; Jared Diamond
Effect of diet on glucose transporter site density along the intestinal crypt-villus axis.
The American journal of physiology 1992;262(6 Pt 1):G1060-8.
1992: S C Cramer; William M Pardridge; Bruce A Hirayama; Ernest M Wright
Colocalization of GLUT2 glucose transporter, sodium/glucose cotransporter, and gamma-glutamyl transpeptidase in rat kidney with double-peroxidase immunocytochemistry.
Diabetes 1992;41(6):766-70.
1992: Ana M Pajor; Bruce A Hirayama; Ernest M Wright
Molecular evidence for two renal Na+/glucose cotransporters.
Biochimica et biophysica acta 1992;1106(1):216-20.
1992: C D Smith; Bruce A Hirayama; Ernest M Wright
Baculovirus-mediated expression of the Na+/glucose cotransporter in Sf9 cells.
Biochimica et biophysica acta 1992;1104(1):151-9.
1992: Bruce A Hirayama; Ernest M Wright
Glycosylation of the rabbit intestinal brush border Na+/glucose cotransporter.
Biochimica et biophysica acta 1992;1103(1):37-44.
1992: Ernest M Wright; Eric Turk; K Hager; L Lescale-Matys; Bruce A Hirayama; S Supplisson; Donald D F Loo
The Na+/glucose cotransporter (SGLT1).
Acta physiologica Scandinavica. Supplementum 1992;607():201-7.
1991: E S Hwang; Bruce A Hirayama; Ernest M Wright
Distribution of the SGLT1 Na+/glucose cotransporter and mRNA along the crypt-villus axis of rabbit small intestine.
Biochemical and biophysical research communications 1991;181(3):1208-17.
1991: Bruce A Hirayama; H C Wong; C D Smith; B A Hagenbuch; Matthias A Hediger; Ernest M Wright
Intestinal and renal Na+/glucose cotransporters share common structures.
The American journal of physiology 1991;261(2 Pt 1):C296-304.
1989: Ernest M Wright; M A Hediger; M J Coady; Bruce A Hirayama; Eric Turk
Molecular biology of Na+/glucose cotransport.
Biochemical Society transactions 1989;17(5):810-1.
1989: T Ikeda; E S Hwang; M J Coady; Bruce A Hirayama; Matthias A Hediger; Ernest M Wright
Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine.
The Journal of membrane biology 1989;110(1):87-95.