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Ken Hirotsu

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TOP 3
Tomonori Nakayama; Rie Omi; Nobuyoshi Esaki; Ken Hirotsu; Keiji Jitsumori; Takashi Kamachi; Tatsuo Kurihara; Kazunari Yoshizawa
Substrate specificity of fluoroacetate dehalogenase: an insight from crystallographic analysis, fluorescence spectroscopy, and theoretical computations.
Rie Omi; Suguru Kurokawa; Hisaaki Mihara; Hideyuki Hayashi; Masaru Goto; Ikuko Miyahara; Tatsuo Kurihara; Ken Hirotsu; Nobuyoshi Esaki
Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase.
Keiji Jitsumori; Rie Omi; Tatsuo Kurihara; Atsushi Kurata; Hisaaki Mihara; Ikuko Miyahara; Ken Hirotsu; Nobuyoshi Esaki
X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1.

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All Publications

2012: Tomonori Nakayama; Rie Omi; Nobuyoshi Esaki; Ken Hirotsu; Keiji Jitsumori; Takashi Kamachi; Tatsuo Kurihara; Kazunari Yoshizawa
Substrate specificity of fluoroacetate dehalogenase: an insight from crystallographic analysis, fluorescence spectroscopy, and theoretical computations.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(27):8392-402.
2010: Rie Omi; Suguru Kurokawa; Hisaaki Mihara; Hideyuki Hayashi; Masaru Goto; Ikuko Miyahara; Tatsuo Kurihara; Ken Hirotsu; Nobuyoshi Esaki
Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase.
The Journal of biological chemistry 2010;285(16):12133-9.
2009: Keiji Jitsumori; Rie Omi; Tatsuo Kurihara; Atsushi Kurata; Hisaaki Mihara; Ikuko Miyahara; Ken Hirotsu; Nobuyoshi Esaki
X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1.
Journal of bacteriology 2009;191(8):2630-7.
2009: Takae Yamauchi; Masaru Goto; Hui-Yuan Wu; Takuma Uo; Tohru Yoshimura; Hisaaki Mihara; Tatsuo Kurihara; Ikuko Miyahara; Ken Hirotsu; Nobuyoshi Esaki
Serine racemase with catalytically active lysinoalanyl residue.
Journal of biochemistry 2009;145(4):421-4.
2007: Rie Omi; Masaru Goto; Ikuko Miyahara; Miho Manzoku; Akio Ebihara; Ken Hirotsu
Crystal structure of monofunctional histidinol phosphate phosphatase from Thermus thermophilus HB8.
Biochemistry 2007;46(44):12618-27.
2007: Rie Omi; Keiji Jitsumori; Takahiro Yamauchi; Susumu Ichiyama; Tatsuo Kurihara; Nobuyoshi Esaki; Nobuo Kamiya; Ken Hirotsu; Ikuko Miyahara
Expression, purification and preliminary X-ray characterization of DL-2-haloacid dehalogenase from Methylobacterium sp. CPA1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 7):586-9.
2006: Masaru Goto; Hideyuki Hayashi; Ikuko Miyahara; Ken Hirotsu; Masahiro Yoshida; Tadao Oikawa
Crystal structures of nonoxidative zinc-dependent 2,6-dihydroxybenzoate (gamma-resorcylate) decarboxylase from Rhizobium sp. strain MTP-10005.
The Journal of biological chemistry 2006;281(45):34365-73.
2006: Chiaki Setoyama; Yasuzo Nishina; Hisashi Mizutani; Ikuko Miyahara; Ken Hirotsu; Nobuo Kamiya; Kiyoshi Shiga; Retsu Miura
Engineering the substrate specificity of porcine kidney D-amino acid oxidase by mutagenesis of the "active-site lid".
Journal of biochemistry 2006;139(5):873-9.
2006: Keiji Tokuoka; Yoshitaka Nakajima; Ken Hirotsu; Ikuko Miyahara; Yasuzo Nishina; Kiyoshi Shiga; Haruhiko Tamaoki; Chiaki Setoyama; Hiromasa Tojo; Retsu Miura
Three-dimensional structure of rat-liver acyl-CoA oxidase in complex with a fatty acid: insights into substrate-recognition and reactivity toward molecular oxygen.
Journal of biochemistry 2006;139(4):789-95.
2005: Masaru Goto; Hisashi Muramatsu; Hisaaki Mihara; Tatsuo Kurihara; Nobuyoshi Esaki; Rie Omi; Ikuko Miyahara; Ken Hirotsu
Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction.
The Journal of biological chemistry 2005;280(49):40875-84.
2005: Masaru Goto; Ikuko Miyahara; Ken Hirotsu; Myra Conway; Neela H Yennawar; Mohammad Mainul Islam; Susan M Hutson
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.
The Journal of biological chemistry 2005;280(44):37246-56.
2005: Mohammad Mainul Islam; Masaru Goto; Ikuko Miyahara; Hiroko Ikushiro; Ken Hirotsu; Hideyuki Hayashi
Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step.
Biochemistry 2005;44(23):8218-29.
2005: Hisashi Muramatsu; Hisaaki Mihara; Masaru Goto; Ikuko Miyahara; Ken Hirotsu; Tatsuo Kurihara; Nobuyoshi Esaki
A new family of NAD(P)H-dependent oxidoreductases distinct from conventional Rossmann-fold proteins.
Journal of bioscience and bioengineering 2005;99(6):541-7.
2005: Ken Hirotsu; Masaru Goto; Akihiro Okamoto; Ikuko Miyahara
Dual substrate recognition of aminotransferases.
Chemical record (New York, N.Y.) 2005;5(3):160-72.
2004: Toshihiro Okamoto; Masato Kuratsu; Masatoshi Kozaki; Ken Hirotsu; Akio Ichimura; Toshio Matsushita; Keiji Okada
Remarkable structure deformation in phenothiazine trimer radical cation.
Organic letters 2004;6(20):3493-6.
2004: Masaru Goto; Rie Omi; Noriko Nakagawa; Ikuko Miyahara; Ken Hirotsu
Crystal structures of CTP synthetase reveal ATP, UTP, and glutamine binding sites.
Structure (London, England : 1993) 2004;12(8):1413-23.
2004: Masaru Goto; Rie Omi; Ikuko Miyahara; Akira Hosono; Hiroyuki Mizuguchi; Hideyuki Hayashi; Hiroyuki Kagamiyama; Ken Hirotsu
Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition.
The Journal of biological chemistry 2004;279(16):16518-25.
2004: Rie Omi; Masaru Goto; Noriko Nakagawa; Ikuko Miyahara; Ken Hirotsu
Expression, purification and preliminary X-ray characterization of histidinol phosphate phosphatase.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 3):574-6.
2003: Akira Hosono; Hiroyuki Mizuguchi; Hideyuki Hayashi; Masaru Goto; Ikuko Miyahara; Ken Hirotsu; Hiroyuki Kagamiyama
Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8.
Journal of biochemistry 2003;134(6):843-51.
2003: Rie Omi; Masaru Goto; Ikuko Miyahara; Hiroyuki Mizuguchi; Hideyuki Hayashi; Hiroyuki Kagamiyama; Ken Hirotsu
Crystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanism.
The Journal of biological chemistry 2003;278(46):46035-45.
2003: Atsuko Satoh; Yoshitaka Nakajima; Ikuko Miyahara; Ken Hirotsu; Takeyuki Tanaka; Yasuzo Nishina; Kiyoshi Shiga; Haruhiko Tamaoki; Chiaki Setoyama; Retsu Miura
Structure of the transition state analog of medium-chain acyl-CoA dehydrogenase. Crystallographic and molecular orbital studies on the charge-transfer complex of medium-chain acyl-CoA dehydrogenase with 3-thiaoctanoyl-CoA.
Journal of biochemistry 2003;134(2):297-304.
2003: Masaru Goto; Rie Omi; Ikuko Miyahara; Mitsuaki Sugahara; Ken Hirotsu
Structures of argininosuccinate synthetase in enzyme-ATP substrates and enzyme-AMP product forms: stereochemistry of the catalytic reaction.
The Journal of biological chemistry 2003;278(25):22964-71.
2003: Hiroyuki Mizuguchi; Hideyuki Hayashi; Ikuko Miyahara; Ken Hirotsu; Hiroyuki Kagamiyama
Characterization of histidinol phosphate aminotransferase from Escherichia coli.
Biochimica et biophysica acta 2003;1647(1-2):321-4.
2003: Atsuko Satoh; Osao Adachi; Katsuyuki Tanizawa; Ken Hirotsu
The active site structure of quinohemoprotein amine dehydrogenase inhibited by p-nitrophenylhydrazine.
Biochimica et biophysica acta 2003;1647(1-2):272-7.
2003: Hideyuki Hayashi; Hiroyuki Mizuguchi; Ikuko Miyahara; Mohammad Mainul Islam; Hiroko Ikushiro; Yoshitaka Nakajima; Ken Hirotsu; Hiroyuki Kagamiyama
Strain and catalysis in aspartate aminotransferase.
Biochimica et biophysica acta 2003;1647(1-2):103-9.
2003: Masaru Goto; Ikuko Miyahara; Hideyuki Hayashi; Hiroyuki Kagamiyama; Ken Hirotsu
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme.
Biochemistry 2003;42(13):3725-33.
2003: Hideyuki Hayashi; Hiroyuki Mizuguchi; Ikuko Miyahara; Yoshitaka Nakajima; Ken Hirotsu; Hiroyuki Kagamiyama
Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis.
The Journal of biological chemistry 2003;278(11):9481-8.
2003: Masaru Goto; Rie Omi; Jun Hoseki; Noriko Nakagawa; Ikuko Miyahara; Ken Hirotsu
Expression, purification and preliminary X-ray characterization of CTP synthetase from Thermus thermophilus HB8.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):551-3.
2003: Masaru Goto; Yoshihiro Agari; Rie Omi; Ikuko Miyahara; Ken Hirotsu
Expression, purification and preliminary X-ray characterization of N-acetyl-gamma-glutamyl-phosphate reductase from Thermus thermophilus HB8.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 2):356-8.
2002: Rui Tamura; Daisuke Fujimoto; Zsolt Lepp; Kentaro Misaki; Hideyuki Miura; Hiroki Takahashi; Takanori Ushio; Tadashi Nakai; Ken Hirotsu
Mechanism of preferential enrichment, an unusual enantiomeric resolution phenomenon caused by polymorphic transition during crystallization of mixed crystals composed of two enantiomers.
Journal of the American Chemical Society 2002;124(44):13139-53.
2002: Rie Omi; Hiroyuki Mizuguchi; Masaru Goto; Ikuko Miyahara; Hideyuki Hayashi; Hiroyuki Kagamiyama; Ken Hirotsu
Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling.
Journal of biochemistry 2002;132(5):759-65.
2002: Masaru Goto; Yoshitaka Nakajima; Ken Hirotsu
Crystal structure of argininosuccinate synthetase from Thermus thermophilus HB8. Structural basis for the catalytic action.
The Journal of biological chemistry 2002;277(18):15890-6.
2002: Yoshitaka Nakajima; Ikuko Miyahara; Ken Hirotsu; Yasuzo Nishina; Kiyoshi Shiga; Chiaki Setoyama; Haruhiko Tamaoki; Retsu Miura
Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase.
Journal of biochemistry 2002;131(3):365-74.
2002: Atsuko Satoh; Jong-Keun Kim; Ikuko Miyahara; Bart Devreese; Isabel Vandenberghe; Ayse Hacisalihoglu; Toshihide Okajima; Shun'ichi Kuroda; Osao Adachi; Johannis A Duine; Jozef Van Beeumen; Katsuyuki Tanizawa; Ken Hirotsu
Crystal structure of quinohemoprotein amine dehydrogenase from Pseudomonas putida. Identification of a novel quinone cofactor encaged by multiple thioether cross-bridges.
The Journal of biological chemistry 2002;277(4):2830-4.
2002: Chiaki Setoyama; Yasuzo Nishina; Haruhiko Tamaoki; Hisashi Mizutani; Ikuko Miyahara; Ken Hirotsu; Kiyoshi Shiga; Retsu Miura
Effects of hydrogen bonds in association with flavin and substrate in flavoenzyme d-amino acid oxidase. The catalytic and structural roles of Gly313 and Thr317.
Journal of biochemistry 2002;131(1):59-69.
2001: Yoshitaka Nakajima; Ikuko Miyahara; Ken Hirotsu; Yasuzo Nishina; Kiyoshi Shiga; Chiaki Setoyama; Haruhiko Tamaoki; Retsu Miura
Crystallization and preliminary X-ray characterization of rat liver acyl-CoA oxidase.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 11):1680-1.
2001: H Ura; T Nakai; S i Kawaguchi; Ikuko Miyahara; Ken Hirotsu; Seiki Kuramitsu
Substrate recognition mechanism of thermophilic dual-substrate enzyme.
Journal of biochemistry 2001;130(1):89-98.
2001: K Okada; Ken Hirotsu; Hideyuki Hayashi; Hiroyuki Kagamiyama
Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
Biochemistry 2001;40(25):7453-63.
2001: K Haruyama; T Nakai; Ikuko Miyahara; Ken Hirotsu; Hiroyuki Mizuguchi; Hideyuki Hayashi; Hiroyuki Kagamiyama
Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme.
Biochemistry 2001;40(15):4633-44.
2001: Toshiji Tada; C T Lu ; Yoshihiro Nakamura; Kei Wada; Ikuko Miyahara; Ken Hirotsu; Y Katsuya ; M Sawada ; Makoto Takao; Takuo Sakai; Keiichiro Nishimura
Crystallization and preliminary X-ray analysis of a novel pectolytic enzyme, polymethoxygalacturonase SX1 from Trichosporon penicillatum.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 3):457-8.
2001: Hiroyuki Mizuguchi; Hideyuki Hayashi; K Okada; Ikuko Miyahara; Ken Hirotsu; Hiroyuki Kagamiyama
Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Biochemistry 2001;40(2):353-60.
2000: Kwang-Hwan Jhee; Tohru Yoshimura; Edith Wilson Miles; S Takeda; Ikuko Miyahara; Ken Hirotsu; K Soda; Y Kawata; Nobuyoshi Esaki
Stereochemistry of the transamination reaction catalyzed by aminodeoxychorismate lyase from Escherichia coli: close relationship between fold type and stereochemistry.
Journal of biochemistry 2000;128(4):679-86.
2000: Hisashi Mizutani; Ikuko Miyahara; Ken Hirotsu; Yasuzo Nishina; Kiyoshi Shiga; Chiaki Setoyama; Retsu Miura
Three-dimensional structure of the purple intermediate of porcine kidney D-amino acid oxidase. Optimization of the oxidative half-reaction through alignment of the product with reduced flavin.
Journal of biochemistry 2000;128(1):73-81.
2000: T Nakai; H Mizutani; Ikuko Miyahara; Ken Hirotsu; S Takeda; Kwang-Hwan Jhee; Tohru Yoshimura; Nobuyoshi Esaki
Three-dimensional structure of 4-amino-4-deoxychorismate lyase from Escherichia coli.
Journal of biochemistry 2000;128(1):29-38.
2000: J Ishijima; T Nakai; S i Kawaguchi; Ken Hirotsu; Seiki Kuramitsu
Free energy requirement for domain movement of an enzyme.
The Journal of biological chemistry 2000;275(25):18939-45.
1999: T Nakai; K Okada; S Akutsu; Ikuko Miyahara; S Kawaguchi; R Kato; Seiki Kuramitsu; Ken Hirotsu
Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate.
Biochemistry 1999;38(8):2413-24.
1999: Akihiro Okamoto; S Ishii; Ken Hirotsu; Hiroyuki Kagamiyama
The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry 1999;38(4):1176-84.
1998: Y Nobe; S i Kawaguchi; H Ura; T Nakai; Ken Hirotsu; R Kato; Seiki Kuramitsu
The novel substrate recognition mechanism utilized by aspartate aminotransferase of the extreme thermophile Thermus thermophilus HB8.
The Journal of biological chemistry 1998;273(45):29554-64.
1998: T Nakai; K Okada; S Kawaguchi; R Kato; S Kuramitsu; Ken Hirotsu
Crystallization and preliminary X-ray characterization of aspartate aminotransferase from an extreme thermophile, Thermus thermophilus HB8.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 5):1032-4.
1998: Akihiro Okamoto; Y Nakai; Hideyuki Hayashi; Ken Hirotsu; Hiroyuki Kagamiyama
Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
Journal of molecular biology 1998;280(3):443-61.
1997: Retsu Miura; Chiaki Setoyama; Yasuzo Nishina; Kiyoshi Shiga; Hisashi Mizutani; Ikuko Miyahara; Ken Hirotsu
Structural and mechanistic studies on D-amino acid oxidase x substrate complex: implications of the crystal structure of enzyme x substrate analog complex.
Journal of biochemistry 1997;122(4):825-33.
1997: K Okada; Ken Hirotsu; M Sato; H Hayashi; Hiroyuki Kagamiyama
Three-dimensional structure of Escherichia coli branched-chain amino acid aminotransferase at 2.5 A resolution.
Journal of biochemistry 1997;121(4):637-41.
1997: E T Mollova; D E Metzler; A Kintanar; Hiroyuki Kagamiyama; H Hayashi; Ken Hirotsu; Ikuko Miyahara
Use of 1H-15N heteronuclear multiple-quantum coherence NMR spectroscopy to study the active site of aspartate aminotransferase.
Biochemistry 1997;36(3):615-25.
1996: H Mizutani; Ikuko Miyahara; Ken Hirotsu; Yasuzo Nishina; Kiyoshi Shiga; Chiaki Setoyama; Retsu Miura
Three-dimensional structure of porcine kidney D-amino acid oxidase at 3.0 A resolution.
Journal of biochemistry 1996;120(1):14-7.
1996: Chiaki Setoyama; Retsu Miura; Yasuzo Nishina; Kiyoshi Shiga; H Mizutani; Ikuko Miyahara; Ken Hirotsu
Crystallization of expressed porcine kidney D-amino acid oxidase and preliminary X-ray crystallographic characterization.
Journal of biochemistry 1996;119(6):1114-7.
1994: D E Metzler; C M Metzler; R D Scott; E T Mollova; Hiroyuki Kagamiyama; T Yano; Seiki Kuramitsu; H Hayashi; Ken Hirotsu; Ikuko Miyahara
NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli.
The Journal of biological chemistry 1994;269(45):28027-33.
1994: Ikuko Miyahara; Ken Hirotsu; H Hayashi; Hiroyuki Kagamiyama
X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from Escherichia coli in three forms.
Journal of biochemistry 1994;116(5):1001-12.
1994: A Okamoto; T Higuchi; Ken Hirotsu; Seiki Kuramitsu; Hiroyuki Kagamiyama
X-ray crystallographic study of pyridoxal 5'-phosphate-type aspartate aminotransferases from Escherichia coli in open and closed form.
Journal of biochemistry 1994;116(1):95-107.
1993: T Yano; Y Hinoue; V J Chen; D E Metzler; Ikuko Miyahara; Ken Hirotsu; Hiroyuki Kagamiyama
Role of an active site residue analyzed by combination of mutagenesis and coenzyme analog.
Journal of molecular biology 1993;234(4):1218-29.
1992: A Okamoto; Ken Hirotsu
[Protein engineering. I: X-ray crystallographic study of aspartate aminotransferase and its mutant enzymes].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1992;37(13):2231-42.
1991: K Inoue; Seiki Kuramitsu; A Okamoto; Ken Hirotsu; T Higuchi; Hiroyuki Kagamiyama
Site-directed mutagenesis of Escherichia coli aspartate aminotransferase: role of Tyr70 in the catalytic processes.
Biochemistry 1991;30(31):7796-801.
1991: Y Kojima; Y Ikeda; E Kumata; J Maruo; A Okamoto; Ken Hirotsu; K Shibata; A Ohsuka
Preparations, solution conformation and molecular structures of N,N'-ethylene-bridged dipeptides and their derivatives.
International journal of peptide and protein research 1991;37(6):468-75.
1991: K Inoue; Seiki Kuramitsu; A Okamoto; Ken Hirotsu; T Higuchi; Y Morino; Hiroyuki Kagamiyama
Tyr225 in aspartate aminotransferase: contribution of the hydrogen bond between Tyr225 and coenzyme to the catalytic reaction.
Journal of biochemistry 1991;109(4):570-6.
1991: M H Sung; K Tanizawa; H Tanaka; Seiki Kuramitsu; Hiroyuki Kagamiyama; Ken Hirotsu; A Okamoto; T Higuchi; K Soda
Thermostable aspartate aminotransferase from a thermophilic Bacillus species. Gene cloning, sequence determination, and preliminary x-ray characterization.
The Journal of biological chemistry 1991;266(4):2567-72.
1990: S Kamitori; A Okamoto; Ken Hirotsu; T Higuchi; Seiki Kuramitsu; Hiroyuki Kagamiyama; Y Matsuura; Y Katsube
Three-dimensional structures of aspartate aminotransferase from Escherichia coli and its mutant enzyme at 2.5 A resolution.
Journal of biochemistry 1990;108(2):175-84.
1988: S Kamitori; Ken Hirotsu; T Higuchi; K Kondo; K Inoue; Seiki Kuramitsu; Hiroyuki Kagamiyama; Y Higuchi; N Yasuoka; M Kusunoki
Three-dimensional structure of aspartate aminotransferase from Escherichia coli at 2.8 A resolution.
Journal of biochemistry 1988;104(3):317-8.
1987: S Kamitori; Ken Hirotsu; T Higuchi; K Kondo; K Inoue; Seiki Kuramitsu; Hiroyuki Kagamiyama; Y Higuchi; N Yasuoka; M Kusunoki
Overproduction and preliminary X-ray characterization of aspartate aminotransferase from Escherichia coli.
Journal of biochemistry 1987;101(3):813-6.