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Junichi Hitomi

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Futoshi Yukioka; Shinsuke Matsuzaki; Keisuke Kawamoto; Yoshihisa Koyama; Junichi Hitomi; Taiichi Katayama; Masaya Tohyama
Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis.
Satoru Yamagishi; Yoshihisa Koyama; Taiichi Katayama; Manabu Taniguchi; Junichi Hitomi; Masaaki Kato; Masashi Aoki; Yasuto Itoyama; Shinsuke Kato; Masaya Tohyama
An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation.
Kayoko Oono; Toshiyuki Yoneda; Takayuki Manabe; Satoru Yamagishi; Satoshi Matsuda; Junichi Hitomi; Shingo Miyata; Tatsuyoshi Mizuno; Kazunori Imaizumi; Taiichi Katayama; Masaya Tohyama
JAB1 participates in unfolded protein responses by association and dissociation with IRE1.

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All Publications

2008: Futoshi Yukioka; Shinsuke Matsuzaki; Keisuke Kawamoto; Yoshihisa Koyama; Junichi Hitomi; Taiichi Katayama; Masaya Tohyama
Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis.
Neurochemistry international 2008;52(4-5):683-7.
2007: Satoru Yamagishi; Yoshihisa Koyama; Taiichi Katayama; Manabu Taniguchi; Junichi Hitomi; Masaaki Kato; Masashi Aoki; Yasuto Itoyama; Shinsuke Kato; Masaya Tohyama
An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation.
PloS one 2007;2(10):e1030.
2004: Kayoko Oono; Toshiyuki Yoneda; Takayuki Manabe; Satoru Yamagishi; Satoshi Matsuda; Junichi Hitomi; Shingo Miyata; Tatsuyoshi Mizuno; Kazunori Imaizumi; Taiichi Katayama; Masaya Tohyama
JAB1 participates in unfolded protein responses by association and dissociation with IRE1.
Neurochemistry international 2004;45(5):765-72.
2004: Taiichi Katayama; Kazunori Imaizumi; Takayuki Manabe; Junichi Hitomi; Takashi Kudo; Masaya Tohyama
Induction of neuronal death by ER stress in Alzheimer's disease.
Journal of chemical neuroanatomy 2004;28(1-2):67-78.
2004: Junichi Hitomi; Taiichi Katayama; Yutaka Eguchi; Takashi Kudo; Manabu Taniguchi; Yoshihisa Koyama; Takayuki Manabe; Satoru Yamagishi; Yoshio Bando; Kazunori Imaizumi; Yoshihide Tsujimoto; Masaya Tohyama
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death.
The Journal of cell biology 2004;165(3):347-56.
2004: Junichi Hitomi; Taiichi Katayama; Manabu Taniguchi; Akiko Honda; Kazunori Imaizumi; Masaya Tohyama
Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.
Neuroscience letters 2004;357(2):127-30.
2004: Taiichi Katayama; Kazunori Imaizumi; Toshiyuki Yoneda; Manabu Taniguchi; Akiko Honda; Takayuki Manabe; Junichi Hitomi; Kayoko Oono; Kousuke Baba; Shingo Miyata; Shinsuke Matsuzaki; Koichi Takatsuji; Masaya Tohyama
Role of ARF4L in recycling between endosomes and the plasma membrane.
Cellular and molecular neurobiology 2004;24(1):137-47.
2003: Takayuki Manabe; Taiichi Katayama; Naoyuki Sato; Fumi Gomi; Junichi Hitomi; Takeshi Yanagita; Takashi Kudo; Akiko Honda; Yasuo Mori; Shinsuke Matsuzaki; Kazunori Imaizumi; Akila Mayeda; Masaya Tohyama
Induced HMGA1a expression causes aberrant splicing of Presenilin-2 pre-mRNA in sporadic Alzheimer's disease.
Cell death and differentiation 2003;10(6):698-708.
2001: Naoyuki Sato; Kazunori Imaizumi; Takayuki Manabe; Manabu Taniguchi; Junichi Hitomi; Taiichi Katayama; Toshiyuki Yoneda; Takashi Morihara; Yuichi Yasuda; T Takagi; Takashi Kudo; Takeo Tsuda; Yasuto Itoyama; T Makifuchi; Paul E Fraser; Peter St George-Hyslop; Masaya Tohyama
Increased production of beta-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2.
The Journal of biological chemistry 2001;276(3):2108-14.
2000: Takashi Morihara; Taiichi Katayama; Naoyuki Sato; Toshiyuki Yoneda; Takayuki Manabe; Junichi Hitomi; H Abe; Kazunori Imaizumi; Masaya Tohyama
Absence of endoproteolysis but no effects on amyloid beta production by alternative splicing forms of presenilin-1, which lack exon 8 and replace D257A.
Brain research. Molecular brain research 2000;85(1-2):85-90.
2000: K Miyoshi; Taiichi Katayama; Kazunori Imaizumi; Manabu Taniguchi; Yasuo Mori; Junichi Hitomi; Daishi Yui; Takayuki Manabe; Fumi Gomi; Toshiyuki Yoneda; Masaya Tohyama
Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line.
Brain research. Molecular brain research 2000;85(1-2):68-76.
2000: Fumi Gomi; Kazunori Imaizumi; Toshiyuki Yoneda; Manabu Taniguchi; Yasuo Mori; K Miyoshi; Junichi Hitomi; Takashi Fujikado; Yasuo Tano; Masaya Tohyama
Molecular cloning of a novel membrane glycoprotein, pal, specifically expressed in photoreceptor cells of the retina and containing leucine-rich repeat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(9):3206-13.
2000: Toshiyuki Yoneda; Kazunori Imaizumi; Masahiro Maeda; Daishi Yui; Takayuki Manabe; Taiichi Katayama; Naoyuki Sato; Fumi Gomi; Takashi Morihara; Yasuo Mori; K Miyoshi; Junichi Hitomi; Shinya Ugawa; Satoru Yamada; Masaru Okabe; Masaya Tohyama
Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein.
The Journal of biological chemistry 2000;275(15):11114-20.
1999: Taiichi Katayama; Kazunori Imaizumi; Naoyuki Sato; K Miyoshi; Takashi Kudo; Junichi Hitomi; Takashi Morihara; Toshiyuki Yoneda; Fumi Gomi; Yasuo Mori; Y Nakano; J Takeda; Takeo Tsuda; Yasuto Itoyama; Ohoshi Murayama; A Takashima; Peter St George-Hyslop; Masatoshi Takeda; Masaya Tohyama
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
Nature cell biology 1999;1(8):479-85.