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Walter Hittelman

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Arun Gupta; Walter N Hittelman; Nobuo Horikoshi; Clayton R Hunt; K Komal; Rakesh Kumar; Thomas Ludwig; Juhee Pae; Raj K Pandita; Kiyoshi Ariizumi; Chandan Guha; Jerry W Shay; Mayank Singh; Tej K Pandita
T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice.
Hong Zhou; Nhan L Tran; Michele B Weiss; Jeffrey A Winkles; Hideo Yagita; Kaushal Asrani; Sharron A N Brown; Emily Cheng; Suhendan Ekmekcioglu; Walter N Hittelman; John W Marks; Khalid A Mohamedali; Keeley K Phillips; Michael G Rosenblum
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
Jan Zimak; Dzifa Y Duose; Walter N Hittelman; Ryan M Schweller; Michael R Diehl
Programming in situ immunofluorescence intensities through interchangeable reactions of dynamic DNA complexes.

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2013: Arun Gupta; Walter N Hittelman; Nobuo Horikoshi; Clayton R Hunt; K Komal; Rakesh Kumar; Thomas Ludwig; Juhee Pae; Raj K Pandita; Kiyoshi Ariizumi; Chandan Guha; Jerry W Shay; Mayank Singh; Tej K Pandita
T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice.
Mutagenesis 2013;28(3):263-70.
2013: Hong Zhou; Nhan L Tran; Michele B Weiss; Jeffrey A Winkles; Hideo Yagita; Kaushal Asrani; Sharron A N Brown; Emily Cheng; Suhendan Ekmekcioglu; Walter N Hittelman; John W Marks; Khalid A Mohamedali; Keeley K Phillips; Michael G Rosenblum
The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment.
The Journal of investigative dermatology 2013;133(4):1052-62.
2012: Jan Zimak; Dzifa Y Duose; Walter N Hittelman; Ryan M Schweller; Michael R Diehl
Programming in situ immunofluorescence intensities through interchangeable reactions of dynamic DNA complexes.
Chembiochem : a European journal of chemical biology 2012;13(18):2722-8.
2012: Mi-Ae Lyu; John W Marks; Lawrence H Cheung; Min-Jeong Cho; Walter N Hittelman; Yuying Liu; Michael G Rosenblum
Bax345/BLyS: a novel, completely human fusion protein targeting malignant B cells and delivering a unique mitochondrial toxin.
Cancer letters 2012;322(2):159-68.
2012: Ryan M Schweller; Jan Zimak; Dzifa Y Duose; Walter N Hittelman; Amina A Qutub; Michael R Diehl
Multiplexed in situ immunofluorescence using dynamic DNA complexes.
Angewandte Chemie (International ed. in English) 2012;51(37):9292-6.
2012: Mi-Ae Lyu; John W Marks; Lan V Pham; Bharat B Aggarwal; Kwang Seok Ahn; Lawrence H Cheung; Min-Jeong Cho; Richard J Ford; Walter N Hittelman; Bokyung Sung; Archito Tamayo; Michael G Rosenblum
The therapeutic effects of rGel/BLyS fusion toxin in in vitro and in vivo models of mantle cell lymphoma.
Biochemical pharmacology 2012;84(4):451-8.
2012: Mohamed Naguib; Jijun J Xu; Jianhua Hu; Bihua Bie; David L Brown; David Cogdell; Suzanne Craig; Philippe Diaz; Walter N Hittelman
Prevention of paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system.
Anesthesia and analgesia 2012;114(5):1104-20.
2012: Dzifa Y Duose; Walter N Hittelman; Arthur R Rogers; Ryan M Schweller; Jan Zimak; Michael R Diehl
Configuring robust DNA strand displacement reactions for in situ molecular analyses.
Nucleic acids research 2012;40(7):3289-98.
2011: Jangsoon Lee; Seung-Hee Ryu; Wen-Cheng Chung; Kathryn Ann Gold; Walter N Hittelman; Shin Myung Kang; Waun Ki Hong; Edward S Kim; Ja Seok Koo
Prevention of bronchial hyperplasia by EGFR pathway inhibitors in an organotypic culture model.
Cancer prevention research (Philadelphia, Pa.) 2011;4(8):1306-15.
2011: Hong Zhou; Hideo Yagita; Lawrence H Cheung; Walter N Hittelman; John W Marks; Michael G Rosenblum; Jeffrey A Winkles
Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells.
Molecular cancer therapeutics 2011;10(7):1276-88.
2011: Shangfeng Liu; Shih-Ya Wang; Nur Yucer; Benjamin P C Chen; Jessica Chu; Walter N Hittelman; Mei Leng; Yi Wang
RING finger and WD repeat domain 3 (RFWD3) associates with replication protein A (RPA) and facilitates RPA-mediated DNA damage response.
The Journal of biological chemistry 2011;286(25):22314-22.
2011: Khalid A Mohamedali; Latha Ramdas; Sophia Ran; Lawrence H Cheung; Candelaria Gomez-Manzano; Walter N Hittelman; Sehoon Kim; Philip E Thorpe; Johannes Waltenberger; Jing Xu; Wei Zhang; Michael G Rosenblum
Cytotoxicity of VEGF(121)/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2.
BMC cancer 2011;11():358.
2010: Dzifa Y Duose; Ryan M Schweller; Walter N Hittelman; Michael R Diehl
Multiplexed and reiterative fluorescence labeling via DNA circuitry.
Bioconjugate chemistry 2010;21(12):2327-31.
2010: Walter N Hittelman; Yong Liao; Li Wang; Luka Milas
Are cancer stem cells radioresistant?
Future oncology (London, England) 2010;6(10):1563-76.
2010: Hong Zhou; Yuying Liu; Lawrence H Cheung; Sehoon Kim; Weihe Zhang; Khalid A Mohamedali; Preetha Anand; Walter N Hittelman; Bharat B Aggarwal; Michael G Rosenblum
Characterization and mechanistic studies of a novel melanoma-targeting construct containing IκBa for specific inhibition of nuclear factor-κB activity.
Neoplasia (New York, N.Y.) 2010;12(10):766-77.
2010: Fredika M Robertson; Marcia A Ogasawara; Zaiming Ye; Khoi Chu; Ross Pickei; Bisrat G Debeb; Wendy A Woodward; Walter N Hittelman; Massimo Cristofanilli; Sanford H Barsky
Imaging and analysis of 3D tumor spheroids enriched for a cancer stem cell phenotype.
Journal of biomolecular screening 2010;15(7):820-9.
2009: Hao Sun; De-Pei Li; Shao-Rui Chen; Walter N Hittelman; Hui-Lin Pan
Sensing of blood pressure increase by transient receptor potential vanilloid 1 receptors on baroreceptors.
The Journal of pharmacology and experimental therapeutics 2009;331(3):851-9.
2009: Oliver Riesterer; Kathryn A Mason; Uma Raju; Qiuan Yang; Li Wang; Walter N Hittelman; K Kian Ang; Luka Milas
Enhanced response to C225 of A431 tumor xenografts growing in irradiated tumor bed.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(3):383-7.
2009: Luka Milas; Walter N Hittelman
Cancer stem cells and tumor response to therapy: current problems and future prospects.
Seminars in radiation oncology 2009;19(2):96-105.
2009: James D Cox; Sergio Giralt; Mary L Veazie; Jaffer A Ajani; Janet M Bruner; Ka Wah Chan; Walter N Hittelman; Kelly K Hunt; Revathy B Iyer; Daniel D Karp; Deborah A Kuban; Scott M Lippman; Issam I Raad; Miguel A Rodriguez-Bigas; Leonard A Zwelling; Maurie Markman
Evaluating quality in clinical cancer research: the M.D. Anderson Cancer Center experience.
Oncology 2009;77(2):75-81.
2009: Vassiliki A Papadimitrakopoulou; Julie G Izzo; Diane D Liu; Jeffrey L Myers; Tania L Ceron; Jan Lewin; William N William; Anthea Atwell; J Jack Lee; Ann M Gillenwater; Adel El-Naggar; Xifeng Wu; Scott M Lippman; Walter N Hittelman; Waun Ki Hong
Cyclin D1 and cancer development in laryngeal premalignancy patients.
Cancer prevention research (Philadelphia, Pa.) 2009;2(1):14-21.
2007: Walter N Hittelman; Diane D Liu; Jonathan M Kurie; Reuben Lotan; Jin Soo Lee; Fadlo R Khuri; Heladio Ibarguen; Rodolfo C Morice; Garrett Walsh; Jack A Roth; John D Minna; Jae Y Ro; Anita Broxson; Waun Ki Hong; J Jack Lee
Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.
Journal of the National Cancer Institute 2007;99(21):1603-12.
2007: Julie G Izzo; Rajyalakshmi Luthra; Tsung-Teh Wu; Arlene M Correa; Madan G Luthra; Sharmila Anandasabapathy; K.S. Chao; Mien-Chie Hung; Bharat B Aggarwal; Walter N Hittelman; Jaffer A Ajani
Molecular mechanisms in Barrett's metaplasia and its progression.
Seminars in oncology 2007;34(2 Suppl 1):S2-6.
2007: Julie G Izzo; Tsung-Teh Wu; Xifeng Wu; Joe Ensor; Rajyalakshmi Luthra; Jennifer Pan; Arlene Correa; Stephen G Swisher; K.S. Chao; Walter N Hittelman; Jaffer A Ajani
Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(6):698-707.
2007: Mi-Ae Lyu; Lawrence H Cheung; Walter N Hittelman; John W Marks; Ricardo Aguiar; Michael G Rosenblum
The rGel/BLyS fusion toxin specifically targets malignant B cells expressing the BLyS receptors BAFF-R, TACI, and BCMA.
Molecular cancer therapeutics 2007;6(2):460-70.
2006: Lina Shao; Walter N Hittelman; Jie Lin; Hushan Yang; Jaffer A Ajani; Xifeng Wu
Deficiency of cell cycle checkpoints and DNA repair system predispose individuals to esophageal cancer.
Mutation research 2006;602(1-2):143-50.
2006: Julie G Izzo; Arlene M Correa; Tsung-Teh Wu; Usha Malhotra; K.S. Chao; Rajyalakshmi Luthra; Joe Ensor; Alexander Dekovich; Zhongxing Liao; Walter N Hittelman; Bharat B Aggarwal; Jaffer A Ajani
Pretherapy nuclear factor-kappaB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma.
Molecular cancer therapeutics 2006;5(11):2844-50.
2006: Xifeng Wu; Jian Gu; Tsung-Teh Wu; Stephen G Swisher; Zhongxin Liao; Arlene M Correa; Jun Liu; Carol J Etzel; Christopher I Amos; Maosheng Huang; Silvia S Chiang; Luka Milas; Walter N Hittelman; Jaffer A Ajani
Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(23):3789-98.
2006: Xin Wang; Lee Zou; Tao Lu; Shilai Bao; Kristen E Hurov; Walter N Hittelman; Stephen J Elledge; Lei Li
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress.
Molecular cell 2006;23(3):331-41.
2006: Scott M Lippman; J Jack Lee; Jack W Martin; Adel K El-Naggar; Xiaochun Xu; Dong M Shin; Margaret Thomas; Li Mao; Herbert A Fritsche; Xian Zhou; Vassiliki A Papadimitrakopoulou; Fadlo R Khuri; Hai Tran; Gary L Clayman; Walter N Hittelman; Waun Ki Hong; Reuben Lotan
Fenretinide activity in retinoid-resistant oral leukoplakia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(10):3109-14.
2006: Kristine S Klos; Shannon L Wyszomierski; Menghong Sun; Ming Tan; Xiaoyan Zhou; Ping Li; Wentao Yang; Guosheng Yin; Walter N Hittelman; Dihua Yu
ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells.
Cancer research 2006;66(4):2028-37.
2006: Julie G Izzo; Usha Malhotra; Tsung-Teh Wu; Joe Ensor; Rajyalakshmi Luthra; Jeffrey H Lee; Stephen G Swisher; Zhongxing Liao; K.S. Chao; Walter N Hittelman; Bharat B Aggarwal; Jaffer A Ajani
Association of activated transcription factor nuclear factor kappab with chemoradiation resistance and poor outcome in esophageal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(5):748-54.
2006: Robert A Newman; Peiying Yang; Walter N Hittelman; Tao Lu; Dah H Ho; Dan Ni; Diana Chan; Mary Vijjeswarapu; Carrie Cartwright; Susan Dixon; Edward Felix; Crandell Addington
Oleandrin-mediated oxidative stress in human melanoma cells.
Journal of experimental therapeutics & oncology 2006;5(3):167-81.
2005: Julie G Izzo; Usha Malhotra; Tseung T Wu; Joe Ensor; Ilona M Babenko; Stephen G Swisher; Arlene Correa; Robert S Bresalier; Walter N Hittelman; Jaffer A Ajani
Impact of cyclin D1 A870G polymorphism in esophageal adenocarcinoma tumorigenesis.
Seminars in oncology 2005;32(6 Suppl 9):S11-5.
2005: Heung Gon Kim; Jose-Miguel Yamal; Xiao-Chun Xu; Wei Hu; Iouri Boiko; Adriana C Linares; Anne-Thérèse Vlastos; E Neely Atkinson; Anais Malpica; Walter N Hittelman; Michele Follen
Cervical chromosome 9 polysomy: validation and use as a surrogate endpoint biomarker in a 4-HPR chemoprevention trial.
Gynecologic oncology 2005;99(3 Suppl 1):S32-7.
2005: Xiaojun Liu; Ying Guo; Yexiong Li; Yingjun Jiang; Sherri Chubb; Atsushi Azuma; Peng Huang; Akira Matsuda; Walter N Hittelman; William Plunkett
Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
Cancer research 2005;65(15):6874-81.
2005: Jijiang Zhu; James L Abbruzzese; Julie G Izzo; Walter N Hittelman; Donghui Li
AURKA amplification, chromosome instability, and centrosome abnormality in human pancreatic carcinoma cells.
Cancer genetics and cytogenetics 2005;159(1):10-7.
2005: Marie Wislez; M Loreto Spencer; Julie G Izzo; Denise M Juroske; Kamna Balhara; Dianna D Cody; Roger E Price; Walter N Hittelman; Ignacio I Wistuba; Jonathan M Kurie
Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
Cancer research 2005;65(8):3226-35.
2004: Lei L Chen; Jonathan Trent; Elsie F Wu; Gregory N Fuller; Latha Ramdas; Wei Zhang; A Kevin Raymond; Victor G Prieto; Caroline O Oyedeji; Kelly K Hunt; Raphael E Pollock; Barry W Feig; Kimberly J Hayes; Haesun Choi; Homer A Macapinlac; Walter N Hittelman; Marco De Velasco; Shreyaskumar Patel; Michael A Burgess; Robert S Benjamin; Marsha L Frazier
A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors.
Cancer research 2004;64(17):5913-9.
2004: Jose-Miguel Yamal; Dennis Cox; Walter N Hittelman; Iouri Boiko; Anais Malpica; Martial Guillaud; Calum MacAulay; Michele Follen; Anne-Thérèse Vlastos
Quantitative histopathology and chromosome 9 polysomy in a clinical trial of 4-HPR.
Gynecologic oncology 2004;94(2):296-306.
2004: Shilai Bao; Tao Lu; Xin Wang; Huyong Zheng; Li-E Wang; Qingyi Wei; Walter N Hittelman; Lei Li
Disruption of the Rad9/Rad1/Hus1 (9-1-1) complex leads to checkpoint signaling and replication defects.
Oncogene 2004;23(33):5586-93.
2004: Tao Lu; Walter N Hittelman
Improvement and application of fluorescence inter-simple sequence repeat polymerase chain reaction for the study of subclonal growths in lung epithelial cell populations.
Chest 2004;125(5 Suppl):110S-1S.
2003: Yuying Liu; Lawrence H Cheung; Walter N Hittelman; Michael G Rosenblum
Targeted delivery of human pro-apoptotic enzymes to tumor cells: In vitro studies describing a novel class of recombinant highly cytotoxic agents.
Molecular cancer therapeutics 2003;2(12):1341-50.
2003: Julio Cesar Morales; Zhenfang Xia; Tao Lu; Melissa B Aldrich; Bin Wang; Corina Rosales; Rodney E Kellems; Walter N Hittelman; Stephen J Elledge; Phillip B Carpenter
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability.
The Journal of biological chemistry 2003;278(17):14971-7.
2003: Wen-Shu Wu; Zhi-Xiang Xu; Walter N Hittelman; Paolo Salomoni; Pier Paolo Pandolfi; Kun-Sang Chang
Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway.
The Journal of biological chemistry 2003;278(14):12294-304.
2003: Jonathan M Kurie; Reuben Lotan; J Jack Lee; Jin Soo Lee; Rodolfo C Morice; Diane D Liu; Xiao-Chun Xu; Fadlo R Khuri; Jae Y Ro; Walter N Hittelman; Garrett L Walsh; Jack A Roth; John D Minna; Waun Ki Hong
Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-beta expression in the bronchial epithelium: results from a randomized placebo-controlled trial.
Journal of the National Cancer Institute 2003;95(3):206-14.
2003: Julie G Izzo; Vassiliki A Papadimitrakopoulou; Diane D Liu; Petra L C den Hollander; Ilona M Babenko; Jamie Keck; Adel K El-Naggar; Dong M Shin; J Jack Lee; Waun Ki Hong; Walter N Hittelman
Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer.
Journal of the National Cancer Institute 2003;95(3):198-205.
2003: Xiao-Feng Le; Walter N Hittelman; Jiaxin Liu; Amanda McWatters; Chun Li; Gordon B Mills; Robert C Bast
Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis.
Oncogene 2003;22(4):484-97.
2002: Vassiliki A Papadimitrakopoulou; Diane D Liu; Li Mao; Dong M Shin; Adel El-Naggar; Heladio Ibarguen; J Jack Lee; Waun Ki Hong; Walter N Hittelman
Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(12):1605-10.
2002: Christopher T Richie; Carolyn Peterson; Tao Lu; Walter N Hittelman; Phillip B Carpenter; Randy J Legerski
hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage.
Molecular and cellular biology 2002;22(24):8635-47.
2002: S Eva Singletary; E Neely Atkinson; Ashraful Hoque; Nour Sneige; Aysegul A Sahin; Herbert A Fritsche; Reuben Lotan; Tao Lu; Walter N Hittelman; Therese B Bevers; Carol B Stelling; Scott M Lippman
Phase II clinical trial of N-(4-Hydroxyphenyl)retinamide and tamoxifen administration before definitive surgery for breast neoplasia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2835-42.
2002: Vincent Grégoire; K. Kian Ang; Jean-François Rosier; Marc Beauduin; Adam S Garden; Marc Hamoir; Walter N Hittelman; Yves Humblet; Fadlo R Khuri; Luka Milas; Carine Mitine; Pierre Scalliet
A phase I study of fludarabine combined with radiotherapy in patients with intermediate to locally advanced head and neck squamous cell carcinoma.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2002;63(2):187-93.
2001: Walter N Hittelman
Genetic instability in epithelial tissues at risk for cancer.
Annals of the New York Academy of Sciences 2001;952():1-12.
2001: Michele Follen; E Neely Atkinson; David Schottenfeld; Anais Malpica; L West; Scott M Lippman; Changping Zou; Walter N Hittelman; Reuben Lotan; Waun Ki Hong
A randomized clinical trial of 4-hydroxyphenylretinamide for high-grade squamous intraepithelial lesions of the cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(11):3356-65.
2001: Vassiliki A Papadimitrakopoulou; Julie G Izzo; Li Mao; J Keck; D Hamilton; Dong M Shin; Adel El-Naggar; P den Hollander; Diane Liu; Walter N Hittelman; Waun Ki Hong
Cyclin D1 and p16 alterations in advanced premalignant lesions of the upper aerodigestive tract: role in response to chemoprevention and cancer development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3127-34.
2001: Jean-Charles Soria; Chulso Moon; Luo Wang; Walter N Hittelman; S J Jang; Shi-Yong Sun; J Jack Lee; Diane Liu; Jonathan M Kurie; Rodolfo C Morice; Jin S Lee; Waun Ki Hong; Li Mao
Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers.
Journal of the National Cancer Institute 2001;93(16):1257-63.
2001: J Jack Lee; Diane Liu; Jin S Lee; Jonathan M Kurie; Fadlo R Khuri; Heladio Ibarguen; Rodolfo C Morice; Garrett Walsh; Jae Y Ro; Anita Broxson; Waun Ki Hong; Walter N Hittelman
Long-term impact of smoking on lung epithelial proliferation in current and former smokers.
Journal of the National Cancer Institute 2001;93(14):1081-8.
2001: Dong M Shin; Navapun Charuruks; Scott M Lippman; J Jack Lee; Jae Y Ro; Waun Ki Hong; Walter N Hittelman
p53 protein accumulation and genomic instability in head and neck multistep tumorigenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(6):603-9.
2001: Jeri Kim; Dong M Shin; Adel El-Naggar; Jin S Lee; C Corrales; Scott M Lippman; Waun Ki Hong; Walter N Hittelman
Chromosome polysomy and histological characteristics in oral premalignant lesions.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(4):319-25.
2001: Fadlo R Khuri; Jin S Lee; Scott M Lippman; J Jack Lee; Shyla K Kalapurakal; R Yu; Jae Y Ro; Rodolfo C Morice; Waun Ki Hong; Walter N Hittelman
Modulation of proliferating cell nuclear antigen in the bronchial epithelium of smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(4):311-8.
2001: Ashraful Hoque; Scott M Lippman; Iouri Boiko; E Neely Atkinson; Nour Sneige; Aysegul Sahin; Donna M Weber; S Risin; Michael D Lagios; R Schwarting; William Colburn; Kapil Dhingra; Michele Follen; Gary J Kelloff; C W Boone; Walter N Hittelman
Quantitative nuclear morphometry by image analysis for prediction of recurrence of ductal carcinoma in situ of the breast.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(3):249-59.
2000: H J Roh; Dong M Shin; Jin S Lee; Jae Y Ro; Michael A Tainsky; Waun Ki Hong; Walter N Hittelman
Visualization of the timing of gene amplification during multistep head and neck tumorigenesis.
Cancer research 2000;60(22):6496-502.
2000: Eva Singletary; R Lieberman; Neely Atkinson; Nour Sneige; Aysegul Sahin; Susanne Tolley; M Colchin; Therese B Bevers; Carol B Stelling; Bruno D Fornage; Herbert A Fritsche; Walter N Hittelman; Gary J Kelloff; Scott M Lippman
Novel translational model for breast cancer chemoprevention study: accrual to a presurgical intervention with tamoxifen and N-[4-hydroxyphenyl] retinamide.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(10):1087-90.
2000: K Tae; Adel K El-Naggar; E Yoo; Lei Feng; J Jack Lee; Waun Ki Hong; Walter N Hittelman; Dong M Shin
Expression of vascular endothelial growth factor and microvessel density in head and neck tumorigenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2821-8.
2000: J Jack Lee; Waun Ki Hong; Walter N Hittelman; Li Mao; Reuben Lotan; Dong M Shin; Steven E Benner; Xiao-Chun Xu; Jin S Lee; VM Papadimitrakopoulou; C Geyer; C Perez; Jack W Martin; Adel K El-Naggar; Scott M Lippman
Predicting cancer development in oral leukoplakia: ten years of translational research.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1702-10.
2000: Dong M Shin; Li Mao; VM Papadimitrakopoulou; Gary L Clayman; Adel El-Naggar; H J Shin; J Jack Lee; Jin S Lee; Ann M Gillenwater; Jeffrey L Myers; Scott M Lippman; Walter N Hittelman; Waun Ki Hong
Biochemopreventive therapy for patients with premalignant lesions of the head and neck and p53 gene expression.
Journal of the National Cancer Institute 2000;92(1):69-73.
2000: Patrice Mathevet; Lucien Frappart; Walter N Hittelman
[Cervix dysplasias: study of Rb and p53 gene expression and correlation with mitotic activity].
Gynécologie, obstétrique & fertilité 2000;28(1):44-50.
1999: Neal Poulin; Iouri Boiko; Calum MacAulay; C Boone; K Nishioka; Walter N Hittelman; M F Mitchell
Nuclear morphometry as an intermediate endpoint biomarker in chemoprevention of cervical carcinoma using alpha-difluoromethylornithine.
Cytometry 1999;38(5):214-23.
1999: V Gregoire; Walter N Hittelman; Jean-François Rosier; Luka Milas
Chemo-radiotherapy: radiosensitizing nucleoside analogues (review).
Oncology reports 1999;6(5):949-57.
1999: Xiao-Feng Le; Y Groner; Steven M Kornblau; Y Gu; Walter N Hittelman; Ditsa Levanon; Kapil Mehta; Ralph B Arlinghaus; Kun-Sang Chang
Regulation of AML2/CBFA3 in hematopoietic cells through the retinoic acid receptor alpha-dependent signaling pathway.
The Journal of biological chemistry 1999;274(31):21651-8.
1999: Navapun Charuruks; Dong M Shin; Narin Voravud; J Y Ro; Waun Ki Hong; Walter N Hittelman
P53 expression and polysomies of chromosome 9, 17 in head and neck cancer prognosis.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 1999;82(5):466-76.
1999: Jin S Lee; Ritsuko Komaki; Rodolfo C Morice; Jae Y Ro; Shyla K Kalapurakal; RA Schea; WK Murphy; Dong M Shin; N T Fox; Garrett L Walsh; Walter N Hittelman; Waun Ki Hong
A pilot clinical laboratory trial of paclitaxel and endobronchial brachytherapy in patients with non-small cell lung cancer.
Seminars in radiation oncology 1999;9(2 Suppl 1):121-9.
1999: Luka Milas; T Fujii; Nancy Hunter; Mohamed A Elshaikh; Kathy Mason; William Plunkett; K. Kian Ang; Walter N Hittelman
Enhancement of tumor radioresponse in vivo by gemcitabine.
Cancer research 1999;59(1):107-14.
1998: Julie G Izzo; Vassiliki A Papadimitrakopoulou; X Q Li; Heladio Ibarguen; Jin S Lee; Jae Y Ro; Adel El-Naggar; Waun Ki Hong; Walter N Hittelman
Dysregulated cyclin D1 expression early in head and neck tumorigenesis: in vivo evidence for an association with subsequent gene amplification.
Oncogene 1998;17(18):2313-22.
1998: Li Mao; Adel K El-Naggar; Vassiliki A Papadimitrakopoulou; Dong M Shin; H C Shin; Y Fan; Xinhui Zhou; Gary L Clayman; J Jack Lee; Jin S Lee; Walter N Hittelman; Scott M Lippman; Waun Ki Hong
Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy.
Journal of the National Cancer Institute 1998;90(20):1545-51.
1998: Iouri Boiko; MF Mitchell; Wei Hu; D K Pandey; P Mathevet; Anais Malpica; Walter N Hittelman
Epidermal growth factor receptor expression in cervical intraepithelial neoplasia and its modulation during an alpha-difluoromethylornithine chemoprevention trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(6):1383-91.
1998: MF Mitchell; Guillermo Tortolero-Luna; J Jack Lee; Walter N Hittelman; Reuben Lotan; J Taylor Wharton; Waun Ki Hong; K Nishioka
Phase I dose de-escalation trial of alpha-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):303-10.
1998: Mary Wang; James L Abbruzzese; Helmut Friess; Walter N Hittelman; Douglas B Evans; MC Abbruzzese; Paul J Chiao; Donghui Li
DNA adducts in human pancreatic tissues and their potential role in carcinogenesis.
Cancer research 1998;58(1):38-41.
1997: Iouri Boiko; MF Mitchell; D K Pandey; R A White; Wei Hu; Anais Malpica; K Nishioka; C W Boone; E Neely Atkinson; Walter N Hittelman
DNA image cytometric measurement as a surrogate end point biomarker in a phase I trial of alpha-difluoromethylornithine for cervical intraepithelial neoplasia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(10):849-55.
1997: Wei Hu; MF Mitchell; Iouri Boiko; Adriana C Linares; H G Kim; Anais Malpica; Guillermo Tortolero-Luna; Walter N Hittelman
Progressive dysregulation of proliferation during cervical carcinogenesis as measured by MPM-2 antibody staining.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(9):711-8.
1997: H Konishi; G Steinbach; N H Terry; K Fujita; J Jack Lee; Arnout C Ruifrok; D Spaulding; Patrick M Lynch; J A Dubin; Michael Andreeff; AM Goodacre; T Hattori; Walter N Hittelman
S phase determination in intact colonic crypts by histone H3 messenger RNA in situ hybridization and confocal microscopy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(7):531-6.
1997: Li Mao; Jin S Lee; Jonathan M Kurie; You-Hong Fan; Scott M Lippman; J Jack Lee; Jae Y Ro; Anita Broxson; R Yu; Rodolfo C Morice; Bonnie L Kemp; Fadlo R Khuri; Garrett L Walsh; Walter N Hittelman; Waun Ki Hong
Clonal genetic alterations in the lungs of current and former smokers.
Journal of the National Cancer Institute 1997;89(12):857-62.
1997: Dong M Shin; Xiao-Chun Xu; Scott M Lippman; J Jack Lee; Jin S Lee; John G Batsakis; Jae Y Ro; Jack W Martin; Walter N Hittelman; Reuben Lotan; Waun Ki Hong
Accumulation of p53 protein and retinoic acid receptor beta in retinoid chemoprevention.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(6):875-80.
1997: Vassiliki A Papadimitrakopoulou; Julie G Izzo; Scott M Lippman; Jin S Lee; You-Hong Fan; Gary L Clayman; Jae Y Ro; Walter N Hittelman; Reuben Lotan; Waun Ki Hong; Li Mao
Frequent inactivation of p16INK4a in oral premalignant lesions.
Oncogene 1997;14(15):1799-803.
1996: H Konishi; G Steinbach; Walter N Hittelman; K Fujita; J Jack Lee; GA Glober; Bernard Levin; M Andreeff; AM Goodacre; Nicholas H A Terry
Cell kinetic analysis of intact rat colonic crypts by confocal microscopy and immunofluorescence.
Gastroenterology 1996;111(6):1493-500.
1996: V Grégoire; Nancy Hunter; W A Brock; Walter N Hittelman; William Plunkett; Luka Milas
Improvement in the therapeutic ratio of radiotherapy for a murine sarcoma by indomethacin plus fludarabine.
Radiation research 1996;146(5):548-53.
1996: Jonathan M Kurie; H J Shin; Jin S Lee; Rodolfo C Morice; Jae Y Ro; Scott M Lippman; Walter N Hittelman; R Yu; J Jack Lee; Waun Ki Hong
Increased epidermal growth factor receptor expression in metaplastic bronchial epithelium.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(10):1787-93.
1996: Mary Wang; Kapil Dhingra; Walter N Hittelman; J G Liehr; Mariza de Andrade; Donghui Li
Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1996;5(9):705-10.
1996: Donghui Li; Mary Wang; Lie Cheng; Margaret R Spitz; Walter N Hittelman; Qingyi Wei
In vitro induction of benzo(a)pyrene diol epoxide-DNA adducts in peripheral lymphocytes as a susceptibility marker for human lung cancer.
Cancer research 1996;56(16):3638-41.
1996: K Hamada; Ramon Alemany; W W Zhang; Walter N Hittelman; Reuben Lotan; Jack A Roth; MF Mitchell
Adenovirus-mediated transfer of a wild-type p53 gene and induction of apoptosis in cervical cancer.
Cancer research 1996;56(13):3047-54.
1996: S K Kim; Y Fan; Vassiliki A Papadimitrakopoulou; Gary L Clayman; Walter N Hittelman; Waun Ki Hong; Reuben Lotan; Li Mao
DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma.
Cancer research 1996;56(11):2519-21.
1996: Li Mao; Jin S Lee; You-Hong Fan; Jae Y Ro; John G Batsakis; Scott M Lippman; Walter N Hittelman; Waun Ki Hong
Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment.
Nature medicine 1996;2(6):682-5.
1996: Dong M Shin; Jin S Lee; Scott M Lippman; J Jack Lee; Z N Tu; G Choi; K Heyne; H J Shin; Jae Y Ro; Helmuth Goepfert; Waun Ki Hong; Walter N Hittelman
p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma.
Journal of the National Cancer Institute 1996;88(8):519-29.
1996: H Konishi; G Steinbach; Nicholas H A Terry; J Jack Lee; J A Dubin; GA Glober; K Fujita; D Spaulding; L Cass; Walter N Hittelman
Histone H3 messenger RNA in situ hybridization correlates with in vivo bromodeoxyuridine labeling of S-phase cells in rat colonic epithelium.
Cancer research 1996;56(3):434-7.
1996: Donghui Li; Mary Wang; Kapil Dhingra; Walter N Hittelman
Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology.
Cancer research 1996;56(2):287-93.
1996: Walter N Hittelman; H J Kim; Jin S Lee; Dong M Shin; Scott M Lippman; J Kim; Jae Y Ro; Waun Ki Hong
Detection of chromosome instability of tissue fields at risk: in situ hybridization.
Journal of cellular biochemistry. Supplement 1996;25():57-62.
1996: R C Vyas; S R Frankel; P Agbor; W H Miller; RP Warrell; Walter N Hittelman
Probing the pathobiology of response to all-trans retinoic acid in acute promyelocytic leukemia: premature chromosome condensation/fluorescence in situ hybridization analysis.
Blood 1996;87(1):218-26.
1995: J A Benvenuto; Walter N Hittelman; Leonard A Zwelling; William Plunkett; Tej K Pandita; David Farquhar; Robert A Newman
Biochemical pharmacology of penclomedine (NSC-338720).
Biochemical pharmacology 1995;50(8):1157-64.
1995: Saroj Vadhan-Raj; H E Broxmeyer; Michael Andreeff; J C Bandres; E Stephen Buescher; Robert S Benjamin; Nicholas E Papadopoulos; A Burgess; Shreyaskumar Patel; Carl Plager; Walter N Hittelman; I McAlister; L Garrison; D E Williams
In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study.
Blood 1995;86(6):2098-105.
1995: Jin S Lee; A Yoon; Shyla K Kalapurakal; Jae Y Ro; J Jack Lee; N Tu; Walter N Hittelman; Waun Ki Hong
Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(8):1893-903.
1995: W Ki Hong; Scott M Lippman; Walter N Hittelman; Reuben Lotan
Retinoid chemoprevention of aerodigestive cancer: from basic research to the clinic.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(7):677-86.
1995: V Grégoire; Arnout C Ruifrok; Roger E Price; W A Brock; Walter N Hittelman; William Plunkett; K. Kian Ang
Effect of intra-peritoneal fludarabine on rat spinal cord tolerance to fractionated irradiation.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1995;36(1):50-5.
1995: Tej K Pandita; Walter N Hittelman
Evidence of a chromatin basis for increased mutagen sensitivity associated with multiple primary malignancies of the head and neck.
International journal of cancer. Journal international du cancer 1995;61(5):738-43.
1995: MF Mitchell; Walter N Hittelman; Reuben Lotan; K Nishioka; Guillermo Tortolero-Luna; Rebecca Richards-Kortum; Waun Ki Hong
Chemoprevention trials in the cervix: design, feasibility, and recruitment.
Journal of cellular biochemistry. Supplement 1995;23():104-12.
1995: Scott M Lippman; Dong M Shin; J Jack Lee; John G Batsakis; Reuben Lotan; Michael A Tainsky; Walter N Hittelman; Waun Ki Hong
p53 and retinoid chemoprevention of oral carcinogenesis.
Cancer research 1995;55(1):16-9.
1994: S H Cho; Aysegul Sahin; Gabriel N Hortobagyi; Walter N Hittelman; Kapil Dhingra
Sialyl-Tn antigen expression occurs early during human mammary carcinogenesis and is associated with high nuclear grade and aneuploidy.
Cancer research 1994;54(24):6302-5.
1994: V Grégoire; NT Van; L Clifton Stephens; W A Brock; Luka Milas; William Plunkett; Walter N Hittelman
The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumor radiation response in vivo.
Cancer research 1994;54(23):6201-9.
1994: Dong M Shin; Walter N Hittelman; Waun Ki Hong
Biomarkers in upper aerodigestive tract tumorigenesis: a review.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(8):697-709.
1994: Walter N Hittelman; Tej K Pandita
Possible role of chromatin alteration in the radiosensitivity of ataxia-telangiectasia.
International journal of radiation biology 1994;66(6 Suppl):S109-13.
1994: MF Mitchell; Walter N Hittelman; Waun Ki Hong; Reuben Lotan; D Schottenfeld
The natural history of cervical intraepithelial neoplasia: an argument for intermediate endpoint biomarkers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(7):619-26.
1994: Tej K Pandita; Walter N Hittelman
Increased initial levels of chromosome damage and heterogeneous chromosome repair in ataxia telangiectasia heterozygote cells.
Mutation research 1994;310(1):1-13.
1994: V Grégoire; Nancy Hunter; W A Brock; Luka Milas; William Plunkett; Walter N Hittelman
Fludarabine improves the therapeutic ratio of radiotherapy in mouse tumors after single-dose irradiation.
International journal of radiation oncology, biology, physics 1994;30(2):363-71.
1994: M Tien Kuo; R C Vyas; L X Jiang; Walter N Hittelman
Chromosome breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells.
Molecular and cellular biology 1994;14(8):5202-11.
1994: Dong M Shin; Jae Y Ro; Waun Ki Hong; Walter N Hittelman
Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis.
Cancer research 1994;54(12):3153-9.
1994: Kapil Dhingra; Nour Sneige; Tej K Pandita; D A Johnston; J S Lee; K Emami; Gabriel N Hortobagyi; Walter N Hittelman
Quantitative analysis of chromosome in situ hybridization signal in paraffin-embedded tissue sections.
Cytometry 1994;16(2):100-12.
1994: Saroj Vadhan-Raj; Nicholas E Papadopoulos; Michael A Burgess; K A Linke; Shreyaskumar R Patel; C Hays; A Arcenas; Carl Plager; Andrzej P Kudelka; Walter N Hittelman
Effects of PIXY321, a granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein, on chemotherapy-induced multilineage myelosuppression in patients with sarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):715-24.
1994: V Grégoire; Nancy Hunter; Luka Milas; W A Brock; William Plunkett; Walter N Hittelman
Potentiation of radiation-induced regrowth delay in murine tumors by fludarabine.
Cancer research 1994;54(2):468-74.
1994: Dong M Shin; J Kim; Jae Y Ro; J Hittelman; Jack A Roth; Waun Ki Hong; Walter N Hittelman
Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.
Cancer research 1994;54(2):321-6.
1994: Tej K Pandita; V Gregoire; Kapil Dhingra; Walter N Hittelman
Effect of chromosome size on aberration levels caused by gamma radiation as detected by fluorescence in situ hybridization.
Cytogenetics and cell genetics 1994;67(2):94-101.
1993: Jin S Lee; S Y Kim; Waun Ki Hong; Scott M Lippman; Jae Y Ro; M L Gay; Walter N Hittelman
Detection of chromosomal polysomy in oral leukoplakia, a premalignant lesion.
Journal of the National Cancer Institute 1993;85(23):1951-4.
1993: Dong M Shin; Narin Voravud; Jae Y Ro; Jin S Lee; Waun Ki Hong; Walter N Hittelman
Sequential increases in proliferating cell nuclear antigen expression in head and neck tumorigenesis: a potential biomarker.
Journal of the National Cancer Institute 1993;85(12):971-8.
1993: Narin Voravud; Dong M Shin; Jae Y Ro; Jin S Lee; Waun Ki Hong; Walter N Hittelman
Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis.
Cancer research 1993;53(12):2874-83.
1993: Dong M Shin; Paul J Chiao; Peter G Sacks; H J Shin; Waun Ki Hong; Walter N Hittelman; Michael A Tainsky
Activation of ribosomal protein S2 gene expression in a hamster model of chemically induced oral carcinogenesis.
Carcinogenesis 1993;14(1):163-6.
1993: Walter N Hittelman; Narin Voravud; Dong M Shin; Jin S Lee; Jae Y Ro; Waun Ki Hong
Early genetic changes during upper aerodigestive tract tumorigenesis.
Journal of cellular biochemistry. Supplement 1993;17F():233-6.
1993: LE Robertson; S Chubb; Raymond E Meyn; M Story; R Ford; Walter N Hittelman; William Plunkett
Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine.
Blood 1993;81(1):143-50.
1993: Kapil Dhingra; V Vogel; N Sneige; Aysegul Sahin; C M Aldaz; G N Hortobagyi; Walter N Hittelman
Strategies for the application of biomarkers for risk assessment and efficacy in breast cancer chemoprevention trials.
Journal of cellular biochemistry. Supplement 1993;17G():37-43.
1993: S Y Kim; J S Lee; Jae Y Ro; M L Gay; Waun Ki Hong; Walter N Hittelman
Interphase cytogenetics in paraffin sections of lung tumors by non-isotopic in situ hybridization. Mapping genotype/phenotype heterogeneity.
The American journal of pathology 1993;142(1):307-17.
1992: Saroj Vadhan-Raj; H E Broxmeyer; Walter N Hittelman
Use of granulocyte-macrophage colony-stimulating factor in hematopoietic disorders: biology and nature of response.
Seminars in hematology 1992;29(4 Suppl 3):4-13.
1992: K Nishikawa; Michael G Rosenblum; Robert A Newman; Tej K Pandita; Walter N Hittelman; Nicholas J Donato
Resistance of human cervical carcinoma cells to tumor necrosis factor correlates with their increased sensitivity to cisplatin: evidence of a role for DNA repair and epidermal growth factor receptor.
Cancer research 1992;52(17):4758-65.
1992: Tej K Pandita; Walter N Hittelman
The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia.
Radiation research 1992;131(2):214-23.
1992: Saroj Vadhan-Raj; H E Broxmeyer; Walter N Hittelman; Nicholas E Papadopoulos; S P Chawla; C Fenoglio; S Cooper; E Stephen Buescher; R W Frenck; A Holian
Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: protection at the progenitor cell level.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(8):1266-77.
1992: Jin S Lee; Scott M Lippman; Waun Ki Hong; Jae Y Ro; S Y Kim; Reuben Lotan; Walter N Hittelman
Determination of biomarkers for intermediate end points in chemoprevention trials.
Cancer research 1992;52(9 Suppl):2707s-2710s.
1992: W Zhang; Walter N Hittelman; NT Van; Michael Andreeff; A Deisseroth
The phosphorylation of retinoblastoma gene product in human myeloid leukemia cells during the cell cycle.
Biochemical and biophysical research communications 1992;184(1):212-6.
1992: Tej K Pandita; Walter N Hittelman
Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells.
Radiation research 1992;130(1):94-103.
1992: Kun-Sang Chang; R C Vyas; L L Deaven; J M Trujillo; Sanford A Stass; Walter N Hittelman
PCR amplification of chromosome-specific DNA isolated from flow cytometry-sorted chromosomes.
Genomics 1992;12(2):307-12.
1992: Kapil Dhingra; Aysegul Sahin; J Supak; S Y Kim; Gabriel N Hortobagyi; Walter N Hittelman
Chromosome in situ hybridization on formalin-fixed mammary tissue using non-isotopic, non-fluorescent probes: technical considerations and biological implications.
Breast cancer research and treatment 1992;23(3):201-10.
1991: RP Warrell; S R Frankel; W H Miller; David A Scheinberg; L M Itri; Walter N Hittelman; R Vyas; M Andreeff; A Tafuri; Ann Jakubowski
Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid).
The New England journal of medicine 1991;324(20):1385-93.
1991: Jin S Lee; Jae Y Ro; A A Sahin; Waun Ki Hong; B W Brown; C F Mountain; Walter N Hittelman
Expression of blood-group antigen A--a favorable prognostic factor in non-small-cell lung cancer.
The New England journal of medicine 1991;324(16):1084-90.
1990: Walter N Hittelman; J D Tigaud; Elihu Estey; Saroj Vadhan-Raj
Premature chromosome condensation in the study of minimal residual disease.
Bone marrow transplantation 1990;6 Suppl 1():9-13.
1990: Scott M Lippman; Jin S Lee; Reuben Lotan; Walter N Hittelman; Michael J Wargovich; Waun Ki Hong
Biomarkers as intermediate end points in chemoprevention trials.
Journal of the National Cancer Institute 1990;82(7):555-60.
1990: Saroj Vadhan-Raj; Sima Jeha; S Buescher; A LeMaistre; G Yee; L Lu; J Lloreta; W Keith Hoots; Walter N Hittelman; Jordan U Gutterman
Stimulation of myelopoiesis in a patient with congenital neutropenia: biology and nature of response to recombinant human granulocyte-macrophage colony-stimulating factor.
Blood 1990;75(4):858-64.
1990: Walter N Hittelman
Direct measurement of chromosome repair by premature chromosome condensation.
Progress in clinical and biological research 1990;340B():337-46.
1990: Leonard A Zwelling; J Mayes; Karl Deisseroth; M Hinds; G Grant; Sen Pathak; F D Ledley; R Vyas; Walter N Hittelman
A restriction fragment length polymorphism for human topoisomerase II: possible relationship to drug-resistance.
Cancer communications 1990;2(11):357-61.
1989: S Sen; Walter N Hittelman; L D Teeter; M Tien Kuo
Model for the formation of double minutes from prematurely condensed chromosomes of replicating micronuclei in drug-treated Chinese hamster ovary cells undergoing DNA amplification.
Cancer research 1989;49(23):6731-7.
1989: I Petković; P Agbor; Walter N Hittelman
Cytogenetic evidence for maturation along both the granulocytic erythroid pathways using premature chromosome condensation.
Bone marrow transplantation 1989;4 Suppl 3():19.
1989: I Petkovic; P Agbor; Walter N Hittelman
Simultaneous cell type identification and premature chromosome condensation analysis in a case of multiple myeloma.
Cancer genetics and cytogenetics 1989;39(2):203-17.
1989: Saroj Vadhan-Raj; Walter N Hittelman; H E Broxmeyer; Michael Keating; D Urdal; Jordan U Gutterman
In vivo biologic activities of recombinant human granulocyte-macrophage colony-stimulating factor.
Annals of the New York Academy of Sciences 1989;554():231-40.
1988: Walter N Hittelman; P Agbor; I Petkovic; Borje Andersson; Andrew Lamb; R Walters; Charles Koller; Miloslav Beran
Detection of leukemic clone maturation in vivo by premature chromosome condensation.
Blood 1988;72(6):1950-60.
1988: D Wlodek; Walter N Hittelman
The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells. II. Repair.
Radiation research 1988;115(3):566-75.
1988: D Wlodek; Walter N Hittelman
The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells. I. Initial damage.
Radiation research 1988;115(3):550-65.
1988: Saroj Vadhan-Raj; S Buescher; A LeMaistre; Michael Keating; R Walters; C Ventura; Walter N Hittelman; H E Broxmeyer; Jordan U Gutterman
Stimulation of hematopoiesis in patients with bone marrow failure and in patients with malignancy by recombinant human granulocyte-macrophage colony-stimulating factor.
Blood 1988;72(1):134-41.
1988: Walter N Hittelman; I Petkovic; P Agbor
Improvements in the premature chromosome condensation technique for cytogenetic analysis.
Cancer genetics and cytogenetics 1988;30(2):301-12.
1988: Walter N Hittelman; P Sen
Heterogeneity in chromosome damage and repair rates after bleomycin in ataxia telangiectasia cells.
Cancer research 1988;48(2):276-9.
1987: Saroj Vadhan-Raj; Michael Keating; A LeMaistre; Walter N Hittelman; K McCredie; J M Trujillo; H E Broxmeyer; C Henney; Jordan U Gutterman
Effects of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes.
The New England journal of medicine 1987;317(25):1545-52.
1987: D Wlodek; Walter N Hittelman
The repair of double-strand DNA breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells.
Radiation research 1987;112(1):146-55.
1987: Elihu Estey; R C Adlakha; Walter N Hittelman; Leonard A Zwelling
Cell cycle stage dependent variations in drug-induced topoisomerase II mediated DNA cleavage and cytotoxicity.
Biochemistry 1987;26(14):4338-44.