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Falk Hlubek

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Claudia Schuster; Kai Tran; Claudia Wolff; Karl-Friedrich Becker; Daniela Berg; Claudius Faber; Heinz Höfler; Thomas Kirchner; Sibylle Liebmann; Katharina Malinowsky; Jens Neumann; Simone Reu; Christina Schott; Falk Hlubek
Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues.
C Faber; D Horst; Falk Hlubek; Thomas Kirchner
Overexpression of Dicer predicts poor survival in colorectal cancer.
Claudia Schuster; Jan Budczies; Claudius Faber; Thomas Kirchner; Falk Hlubek
MicroRNA expression profiling of specific cells in complex archival tissue stained by immunohistochemistry.

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All Publications

2012: Claudia Schuster; Kai Tran; Claudia Wolff; Karl-Friedrich Becker; Daniela Berg; Claudius Faber; Heinz Höfler; Thomas Kirchner; Sibylle Liebmann; Katharina Malinowsky; Jens Neumann; Simone Reu; Christina Schott; Falk Hlubek
Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues.
Histopathology 2012;60(6B):E37-50.
2011: C Faber; D Horst; Falk Hlubek; Thomas Kirchner
Overexpression of Dicer predicts poor survival in colorectal cancer.
European journal of cancer (Oxford, England : 1990) 2011;47(9):1414-9.
2011: Claudia Schuster; Jan Budczies; Claudius Faber; Thomas Kirchner; Falk Hlubek
MicroRNA expression profiling of specific cells in complex archival tissue stained by immunohistochemistry.
Laboratory investigation; a journal of technical methods and pathology 2011;91(1):157-65.
2010: Serena Bonin; Falk Hlubek; Jean Benhattar; Carsten Denkert; Manfred Dietel; Pedro L Fernandez; Gerald Höfler; Hannelore Kothmaier; Bozo Kruslin; Chiara Maria Mazzanti; Aurel Perren; Helmuth Popper; Aldo Scarpa; Paula Soares; Giorgio Stanta; Patricia J T A Groenen
Multicentre validation study of nucleic acids extraction from FFPE tissues.
Virchows Archiv : an international journal of pathology 2010;457(3):309-17.
2009: David Horst; Jan Budczies; Thomas Brabletz; Thomas Kirchner; Falk Hlubek
Invasion associated up-regulation of nuclear factor kappaB target genes in colorectal cancer.
Cancer 2009;115(21):4946-58.
2009: Claudius Faber; Thomas Kirchner; Falk Hlubek
The impact of microRNAs on colorectal cancer.
Virchows Archiv : an international journal of pathology 2009;454(4):359-67.
2009: Stella Wassermann; Silvio Scheel; Elke Hiendlmeyer; Richard Palmqvist; David Horst; Falk Hlubek; Angela Haynl; Lydia Kriegl; Simone Reu; Susanne Merkel; Thomas Brabletz; Thomas Kirchner; Andreas Jung
p16INK4a is a beta-catenin target gene and indicates low survival in human colorectal tumors.
Gastroenterology 2009;136(1):196-205.e2.
2008: Simone Spaderna; Otto Schmalhofer; Mandy Wahlbuhl; Arno Dimmler; Katja Bauer; Aneesa Sultan; Falk Hlubek; Andreas Jung; Dennis Strand; Andreas Eger; Thomas Kirchner; Jürgen Behrens; Thomas Brabletz
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer.
Cancer research 2008;68(2):537-44.
2007: Falk Hlubek; Thomas Brabletz; Jan Budczies; Sabine Pfeiffer; Andreas Jung; Thomas Kirchner
Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer.
International journal of cancer. Journal international du cancer 2007;121(9):1941-8.
2007: Falk Hlubek; Simone Spaderna; Otto Schmalhofer; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Wnt/FZD signaling and colorectal cancer morphogenesis.
Frontiers in bioscience : a journal and virtual library 2007;12():458-70.
2006: Simone Spaderna; Otto Schmalhofer; Falk Hlubek; Geert Berx; Andreas Eger; Susanne Merkel; Andreas Jung; Thomas Kirchner; Thomas Brabletz
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer.
Gastroenterology 2006;131(3):830-40.
2006: Falk Hlubek; S Pfeiffer; Jan Budczies; Simone Spaderna; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Securin (hPTTG1) expression is regulated by beta-catenin/TCF in human colorectal carcinoma.
British journal of cancer 2006;94(11):1672-7.
2005: Katharina Beiter; Elke Hiendlmeyer; Thomas Brabletz; Falk Hlubek; Angela Haynl; Claudia Knoll; Thomas Kirchner; Andreas Jung
beta-Catenin regulates the expression of tenascin-C in human colorectal tumors.
Oncogene 2005;24(55):8200-4.
2005: Thomas Brabletz; Andreas Jung; Simone Spaderna; Falk Hlubek; Thomas Kirchner
Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression.
Nature reviews. Cancer 2005;5(9):744-9.
2005: Thomas Brabletz; Falk Hlubek; Simone Spaderna; Otto Schmalhofer; Elke Hiendlmeyer; Andreas Jung; Thomas Kirchner
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and beta-catenin.
Cells, tissues, organs 2005;179(1-2):56-65.
2004: Thomas Brabletz; Simone Spaderna; Jochen Kolb; Falk Hlubek; Gerhard Faller; Christiane J Bruns; Andreas Jung; Jens Nentwich; Isabelle Duluc; Claire Domon-Dell; Thomas Kirchner; Jean-Noel Freund
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression.
Cancer research 2004;64(19):6973-7.
2004: Gerhard Faller; Arno Dimmler; Tilman Rau; Simone Spaderna; Falk Hlubek; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia.
The Journal of pathology 2004;203(4):904-8.
2004: Roland S Croner; Klaus Guenther; Thomas Foertsch; Renate Siebenhaar; Wolfgang M Brueckl; Christian Stremmel; Falk Hlubek; Werner Hohenberger; Bertram Reingruber
Tissue preparation for gene expression profiling of colorectal carcinoma: three alternatives to laser microdissection with preamplification.
The Journal of laboratory and clinical medicine 2004;143(6):344-51.
2004: Elke Hiendlmeyer; Susanne Regus; Stella Wassermann; Falk Hlubek; Angela Haynl; Arno Dimmler; Claudia Koch; Claudia Knoll; Moniek van Beest; Ute Reuning; Thomas Brabletz; Thomas Kirchner; Andreas Jung
Beta-catenin up-regulates the expression of the urokinase plasminogen activator in human colorectal tumors.
Cancer research 2004;64(4):1209-14.
2004: Falk Hlubek; Simone Spaderna; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas.
International journal of cancer. Journal international du cancer 2004;108(2):321-6.
2003: Arno Dimmler; Thomas Brabletz; Falk Hlubek; Manuela Häfner; Tilman Rau; Thomas Kirchner; Gerhard Faller
Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions.
Laboratory investigation; a journal of technical methods and pathology 2003;83(12):1829-37.
2001: Falk Hlubek; Andreas Jung; N Kotzor; Thomas Kirchner; Thomas Brabletz
Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin.
Cancer research 2001;61(22):8089-93.
2001: Thomas Brabletz; Andreas Jung; S Reu; M Porzner; Falk Hlubek; L A Kunz-Schughart; R Knuechel; Thomas Kirchner
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10356-61.
2001: Falk Hlubek; C Löhberg; J Meiler; Andreas Jung; Thomas Kirchner; Thomas Brabletz
Tip60 is a cell-type-specific transcriptional regulator.
Journal of biochemistry 2001;129(4):635-41.
1999: Thomas Brabletz; Andreas Jung; S Dag; Falk Hlubek; Thomas Kirchner
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer.
The American journal of pathology 1999;155(4):1033-8.
1999: Thomas Brabletz; Andreas Jung; Falk Hlubek; C Löhberg; J Meiler; U Suchy; Thomas Kirchner
Negative regulation of CD4 expression in T cells by the transcriptional repressor ZEB.
International immunology 1999;11(10):1701-8.
1999: Sergei Chuvpilo; Andris Avots; Friederike Berberich-Siebelt; J Glöckner; C Fischer; Andreas Kerstan; C Escher; I Inashkina; Falk Hlubek; Eriks Jankevics; T Brabletz; Edgar Serfling
Multiple NF-ATc isoforms with individual transcriptional properties are synthesized in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7294-301.