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Nathan Astrof

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TOP 3
Koichi Yuki; Nathan S Astrof; Clay Bracken; Sulpicio G Soriano; Motomu Shimaoka
Sevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1.
Hongmin Zhang; Nathan S Astrof; Jin-Huan Liu; Jia-huai Wang; Motomu Shimaoka
Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems.
Koichi Yuki; Nathan S Astrof; Clay Bracken; Ronnie Yoo; Whitney Silkworth; Sulpicio G Soriano; Motomu Shimaoka
The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity.

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All Publications

2010: Koichi Yuki; Nathan S Astrof; Clay Bracken; Sulpicio G Soriano; Motomu Shimaoka
Sevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1.
Anesthesiology 2010;113(3):600-9.
2009: Hongmin Zhang; Nathan S Astrof; Jin-Huan Liu; Jia-huai Wang; Motomu Shimaoka
Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(8):2735-40.
2008: Koichi Yuki; Nathan S Astrof; Clay Bracken; Ronnie Yoo; Whitney Silkworth; Sulpicio G Soriano; Motomu Shimaoka
The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(12):4109-16.
2007: Thomas Vorup-Jensen; Travis T Waldron; Nathan S Astrof; Motomu Shimaoka; Timothy A Springer
The connection between metal ion affinity and ligand affinity in integrin I domains.
Biochimica et biophysica acta 2007;1774(9):1148-55.
2006: Nathan S Astrof; Azucena Salas; Motomu Shimaoka; JianFeng Chen; Timothy A Springer
Importance of force linkage in mechanochemistry of adhesion receptors.
Biochemistry 2006;45(50):15020-8.
2006: Motomu Shimaoka; Minsoo Kim; Edward H Cohen; WEI YANG; Nathan S Astrof; Dan Peer; Azucena Salas; Audrey Ferrand; Timothy A Springer
AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):13991-6.
2006: Moonsoo Jin; Gang Song; Christopher V Carman; Yong-Sung Kim; Nathan S Astrof; Motomu Shimaoka; Dane K Wittrup; Timothy A Springer
Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5758-63.
2004: Joel A Butterwick; J Patrick Loria; Nathan S Astrof; Christopher D Kroenke; Roger Cole; Mark Rance; Arthur G Palmer
Multiple time scale backbone dynamics of homologous thermophilic and mesophilic ribonuclease HI enzymes.
Journal of molecular biology 2004;339(4):855-71.
2002: Christopher Jaroniec; Cait E MacPhee; Nathan S Astrof; Christopher M Dobson; Robert G Griffin
Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16748-53.
2002: Nathan S Astrof; Robert G Griffin
Soft-triple resonance solid-state NMR experiments for assignments of U-13C, 15N labeled peptides and proteins.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;158(1-2):157-63.
2001: Nathan S Astrof; C E Lyon; Robert G Griffin
Triple resonance solid state NMR experiments with reduced dimensionality evolution periods.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2001;152(2):303-7.
2001: Melanie Rosay; Ana Carolina Zeri; Nathan S Astrof; Stanley J Opella; Judith Herzfeld; Robert G Griffin
Sensitivity-enhanced NMR of biological solids: dynamic nuclear polarization of Y21M fd bacteriophage and purple membrane.
Journal of the American Chemical Society 2001;123(5):1010-1.
1998: Nathan S Astrof; C Bracken; John Cavanagh; Arthur G Palmer
CO_H(N)CACB experiments for assigning backbone resonances in 13C/15N-labeled proteins.
Journal of biomolecular NMR 1998;11(4):451-6.