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David Ho

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Publications

TOP 3
Chandrabali Ghose; Xinhua Chen; Olivia Chenesseau; Yaoxing Huang; Ciarán P Kelly; Janneke M Verhagen; Jian Yu; David D Ho
Toll-Like Receptor 5-Dependent Immunogenicity and Protective Efficacy of a Recombinant Fusion Protein Vaccine Containing the Nontoxic Domains of Clostridium difficile Toxins A and B and Salmonella enterica Serovar Typhimurium Flagellin in a Mouse Model of Clostridium difficile Disease.
Gerasimos J Zaharatos; David D Ho; Craig Pace; Yang Song; Sandhya Vasan; Jian Yu; Yaoxing Huang
HIV-1 and influenza antigens synthetically linked to IgG2a Fc elicit superior humoral responses compared to unmodified antigens in mice.
Johannes F Scheid; Michael S Seaman; Beatrix Ueberheide; Klara Velinzon; Bruce D Walker; Thiago Y K Oliveira; Florencia Pereyra; John Pietzsch; Pascal Poignard; Alexander Abadir; Pamela J Bjorkman; Farid Boulad; Dennis R Burton; Brian T Chait; Ron Diskin; David Fenyo; David D Ho; Arlene Hurley; Florian Klein; Hugo Mouquet; Sunnie Myung; Michel C Nussenzweig
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.

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All Publications

2013: Chandrabali Ghose; Xinhua Chen; Olivia Chenesseau; Yaoxing Huang; Ciarán P Kelly; Janneke M Verhagen; Jian Yu; David D Ho
Toll-Like Receptor 5-Dependent Immunogenicity and Protective Efficacy of a Recombinant Fusion Protein Vaccine Containing the Nontoxic Domains of Clostridium difficile Toxins A and B and Salmonella enterica Serovar Typhimurium Flagellin in a Mouse Model of Clostridium difficile Disease.
Infection and immunity 2013;81(6):2190-6.
2011: Gerasimos J Zaharatos; David D Ho; Craig Pace; Yang Song; Sandhya Vasan; Jian Yu; Yaoxing Huang
HIV-1 and influenza antigens synthetically linked to IgG2a Fc elicit superior humoral responses compared to unmodified antigens in mice.
Vaccine 2011;30(1):42-50.
2011: Johannes F Scheid; Michael S Seaman; Beatrix Ueberheide; Klara Velinzon; Bruce D Walker; Thiago Y K Oliveira; Florencia Pereyra; John Pietzsch; Pascal Poignard; Alexander Abadir; Pamela J Bjorkman; Farid Boulad; Dennis R Burton; Brian T Chait; Ron Diskin; David Fenyo; David D Ho; Arlene Hurley; Florian Klein; Hugo Mouquet; Sunnie Myung; Michel C Nussenzweig
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Science (New York, N.Y.) 2011;333(6049):1633-7.
2011: David Franco; David F Gardiner; Beatrice H Hahn; Weimin Liu; David D Ho
CD40L-containing virus-like particle as a candidate HIV-1 vaccine targeting dendritic cells.
Journal of acquired immune deficiency syndromes (1999) 2011;56(5):393-400.
2011: Sandhya Vasan; Arlene Hurley; Sarah J Schlesinger; Drew Hannaman; David F Gardiner; Daniel P Dugin; Mar Boente-Carrera; Roselle Vittorino; Marina Caskey; Johanne Andersen; Yaoxing Huang; Josephine H Cox; Tony Tarragona-Fiol; Dilbinder K Gill; Hannah Cheeseman; Lorna Clark; Len Dally; Carol Smith; Claudia Schmidt; Harriet H Park; Jakub T Kopycinski; Jill Gilmour; Patricia Fast; Robert Bernard; David D Ho
In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers.
PloS one 2011;6(5):e19252.
2010: Hugo Mouquet; Johannes F Scheid; Markus J Zoller; Michelle Krogsgaard; Rene G Ott; Shetha Shukair; Maxim N Artyomov; John Pietzsch; Mark Connors; Florencia Pereyra; Bruce D Walker; David D Ho; Patrick C Wilson; Michael S Seaman; Herman N Eisen; Arup K Chakraborty; Thomas J Hope; Jeffrey V Ravetch; Hedda Wardemann; Michel C Nussenzweig
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation.
Nature 2010;467(7315):591-5.
2010: David Franco; Wenjing Li; Fang Qing; Cristina T Stoyanov; Thomas Moran; Charles M Rice; David D Ho
Evaluation of yellow fever virus 17D strain as a new vector for HIV-1 vaccine development.
Vaccine 2010;28(35):5676-85.
2010: Xiangming Li; Masakazu Fujio; Masakazu Imamura; Douglass Wu; Sandhya Vasan; Chi-Huey Wong; David D Ho; Moriya Tsuji
Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(29):13010-5.
2010: Sandhya Vasan; Sarah J Schlesinger; Yaoxing Huang; Arlene Hurley; Angela Lombardo; Zhiwei Chen; Soe Than; Phumla Adesanya; Catherine Bunce; Mark Boaz; Rosanne Boyle; Eddy Sayeed; Lorna Clark; Daniel Dugin; Claudia Schmidt; Yang Song; Laura Seamons; Len Dally; Martin Ho; Carol Smith; Martin Markowitz; Josephine Cox; Dilbinder K Gill; Jill Gilmour; Michael C Keefer; Patricia Fast; David D Ho
Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine.
PloS one 2010;5(1):e8617.
2009: David F Gardiner; Talia Rosenberg; Jerry Zaharatos; David Franco; David D Ho
A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A.
Vaccine 2009;27(27):3598-604.
2008: David D Ho; Paul D Bieniasz
HIV-1 at 25.
Cell 2008;133(4):561-5.
2008: Yaoxing Huang; Zhiwei Chen; Wenyong Zhang; Deborah Gurner; Yang Song; David F Gardiner; David D Ho
Design, construction, and characterization of a dual-promoter multigenic DNA vaccine directed against an HIV-1 subtype C/B' recombinant.
Journal of acquired immune deficiency syndromes (1999) 2008;47(4):403-11.
2008: Zhiwei Chen; Yaoxing Huang; Xiuqing Zhao; Lei Ba; Wenyong Zhang; David D Ho
Design, construction, and characterization of a multigenic modified vaccinia Ankara candidate vaccine against human immunodeficiency virus type 1 subtype C/B'.
Journal of acquired immune deficiency syndromes (1999) 2008;47(4):412-21.
2008: Yaoxing Huang; Alex Chen; Xiangming Li; Zhiwei Chen; Wenyong Zhang; Yang Song; Deborah Gurner; David Gardiner; Sankha Basu; David D Ho; Moriya Tsuji
Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand, alpha-galactosylceramide.
Vaccine 2008;26(15):1807-16.
2008: Yaoxing Huang; Michael Krasnitz; Raul Rabadan; Daniela M Witten; Yang Song; Arnold J Levine; David D Ho; Harlan Robins
A recoding method to improve the humoral immune response to an HIV DNA vaccine.
PloS one 2008;3(9):e3214.
2007: Hannah Yuan Chen; Michele Di Mascio; Alan S Perelson; David D Ho; Linqi Zhang
Determination of virus burst size in vivo using a single-cycle SIV in rhesus macaques.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(48):19079-84.
2007: Lei Ba; Christopher E Yi; Linqi Zhang; David D Ho; Zhiwei Chen
Heterologous MVA-S prime Ad5-S boost regimen induces high and persistent levels of neutralizing antibody response against SARS coronavirus.
Applied microbiology and biotechnology 2007;76(5):1131-6.
2007: Li Liu; Qing Fang; Fei Deng; Hanzhong Wang; Christopher E Yi; Lei Ba; Wenjie Yu; Richard D Lin; Taisheng Li; Zhihong Hu; David D Ho; Linqi Zhang; Zhiwei Chen
Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus.
Journal of virology 2007;81(9):4694-700.
2006: Viviana Simon; David D Ho; Quarraisha Abdool-Karim
HIV/AIDS epidemiology, pathogenesis, prevention, and treatment.
Lancet 2006;368(9534):489-504.
2006: Masakazu Fujio; Douglass Wu; Raquel Garcia-Navarro; David D Ho; Moriya Tsuji; Chi-Huey Wong
Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity.
Journal of the American Chemical Society 2006;128(28):9022-3.
2006: David F Gardiner; Yaoxing Huang; Sankha Basu; Lisa Leung; Yang Song; Zhiwei Chen; David D Ho
Multiple-site DNA vaccination enhances immune responses in mice.
Vaccine 2006;24(3):287-92.
2005: Viviana Simon; Véronique Zennou; Deya Murray; Yaoxing Huang; David D Ho; Paul D Bieniasz
Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification.
PLoS pathogens 2005;1(1):e6.
2005: Christopher E Yi; Lei Ba; Linqi Zhang; David D Ho; Zhiwei Chen
Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain.
Journal of virology 2005;79(18):11638-46.
2005: Michele Di Mascio; Jerome K Percus; Ora E Percus; Martin Markowitz; David D Ho; Alan S Perelson
Duration of an intermittent episode of viremia.
Bulletin of mathematical biology 2005;67(4):885-900.
2005: Guo-Wen Xing; Douglass Wu; Michael A Poles; Amir Horowitz; Moriya Tsuji; David D Ho; Chi-Huey Wong
Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides.
Bioorganic & medicinal chemistry 2005;13(8):2907-16.
2005: Sébastien Pfeffer; Alain Sewer; Mariana Lagos-Quintana; Robert Sheridan; Chris Sander; Friedrich A Grässer; Linda F van Dyk; Kiong Ho; Stewart Shuman; Minchen Chien; James J Russo; Jingyue Ju; Glenn Randall; Brett D Lindenbach; Charles M Rice; Viviana Simon; David D Ho; Mihaela Zavolan; Thomas Tuschl
Identification of microRNAs of the herpesvirus family.
Nature methods 2005;2(4):269-76.
2005: Yuki Kinjo; Douglass Wu; Gisen Kim; Guo-Wen Xing; Michael A Poles; David D Ho; Moriya Tsuji; Kazuyoshi Kawahara; Chi-Huey Wong; Mitchell Kronenberg
Recognition of bacterial glycosphingolipids by natural killer T cells.
Nature 2005;434(7032):520-5.
2005: Martin Markowitz; Hiroshi Mohri; Saurabh Mehandru; Anita Shet; Leslie Berry; Roopa Kalyanaraman; Alexandria Kim; Chris Chung; Patrick Jean-Pierre; Amir Horowitz; Melissa La Mar; Terri Wrin; Neil Parkin; Michael A Poles; Christos J Petropoulos; Michael Mullen; Daniel Boden; David D Ho
Infection with multidrug resistant, dual-tropic HIV-1 and rapid progression to AIDS: a case report.
Lancet 2005;365(9464):1031-8.
2005: Zhiwei Chen; Linqi Zhang; Chuan Qin; Lei Ba; Christopher E Yi; Fengwen Zhang; Qiang Wei; Tian He; Wenjie Yu; Jian Yu; Hong Gao; Xinming Tu; Agegnehu Gettie; Michael Farzan; Kwok-Yung Yuen; David D Ho
Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region.
Journal of virology 2005;79(5):2678-88.
2005: David D Ho
A shot in the arm for AIDS vaccine research.
PLoS medicine 2005;2(2):e36.
2005: Douglass Wu; Guo-Wen Xing; Michael A Poles; Amir Horowitz; Yuki Kinjo; Barbara Sullivan; Vera Bodmer-Narkevitch; Oliver Plettenburg; Mitchell Kronenberg; Moriya Tsuji; David D Ho; Chi-Huey Wong
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1351-6.
2005: Sarah Tuttleton Arron; Ruy M Ribeiro; Agegnehu Gettie; Rudolf Bohm; James Blanchard; Jian Yu; Alan S Perelson; David D Ho; Linqi Zhang
Impact of thymectomy on the peripheral T cell pool in rhesus macaques before and after infection with simian immunodeficiency virus.
European journal of immunology 2005;35(1):46-55.
2004: Linqi Zhang; Zhiwei Chen; Yunzhen Cao; Jian Yu; Guanghan Li; Wenjie Yu; Ning Yin; Shan Mei; Li Li; Peter Balfe; Tian He; Lei Ba; Fengwen Zhang; His-Hsun Lin; Man-Fung Yuen; Ching-Lung Lai; David D Ho
Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in china.
Journal of virology 2004;78(24):13591-9.
2004: Michele Di Mascio; Martin Markowitz; Michael Louie; Arlene Hurley; Christine Hogan; Viviana Simon; dean follmann; David D Ho; Alan S Perelson
Dynamics of intermittent viremia during highly active antiretroviral therapy in patients who initiate therapy during chronic versus acute and early human immunodeficiency virus type 1 infection.
Journal of virology 2004;78(19):10566-73.
2004: Jane A McKeating; L Q Zhang; Carine Logvinoff; Mike Flint; Jie Zhang; Jian Yu; David Butera; David D Ho; Lynn B Dustin; Charles M Rice; Peter Balfe
Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner.
Journal of virology 2004;78(16):8496-505.
2004: Narendra M Dixit; Martin Markowitz; David D Ho; Alan S Perelson
Estimates of intracellular delay and average drug efficacy from viral load data of HIV-infected individuals under antiretroviral therapy.
Antiviral therapy 2004;9(2):237-46.
2004: Michele Di Mascio; Ruy M Ribeiro; Martin Markowitz; David D Ho; Alan S Perelson
Modeling the long-term control of viremia in HIV-1 infected patients treated with antiretroviral therapy.
Mathematical biosciences 2004;188():47-62.
2004: Bharat Ramratnam; Ruy Ribeiro; Tian He; Chris Chung; Viviana Simon; Jeroen Vanderhoeven; Arlene Hurley; Linqi Zhang; Alan S Perelson; David D Ho; Martin Markowitz
Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication.
Journal of acquired immune deficiency syndromes (1999) 2004;35(1):33-7.
2003: Viviana Simon; David D Ho
HIV-1 dynamics in vivo: implications for therapy.
Nature reviews. Microbiology 2003;1(3):181-90.
2003: Michele Di Mascio; Martin Markowitz; Michael Louie; Christine Hogan; Arlene Hurley; Chris Chung; David D Ho; Alan S Perelson
Viral blip dynamics during highly active antiretroviral therapy.
Journal of virology 2003;77(22):12165-72.
2003: Martin Markowitz; Michael Louie; Arlene Hurley; Eugene Sun; Michele Di Mascio; Alan S Perelson; David D Ho
A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo.
Journal of virology 2003;77(8):5037-8.
2003: Michael Louie; Christine Hogan; Michele Di Mascio; Arlene Hurley; Viviana Simon; James Rooney; Nancy Ruiz; Scott C Brun; Eugene Sun; Alan S Perelson; David D Ho; Martin Markowitz
Determining the relative efficacy of highly active antiretroviral therapy.
The Journal of infectious diseases 2003;187(6):896-900.
2003: Jerome K Percus; Ora E Percus; Martin Markowitz; David D Ho; Michele Di Mascio; Alan S Perelson
The distribution of viral blips observed in HIV-1 infected patients treated with combination antiretroviral therapy.
Bulletin of mathematical biology 2003;65(2):263-77.
2002: Xia Jin; Xiaojiang Gao; Murugappan Ramanathan; Geoffrey R Deschenes; George W Nelson; Stephen J O'Brien; James J Goedert; David D Ho; Thomas R O'Brien; Mary Carrington
Human immunodeficiency virus type 1 (HIV-1)-specific CD8+-T-cell responses for groups of HIV-1-infected individuals with different HLA-B*35 genotypes.
Journal of virology 2002;76(24):12603-10.
2002: Ruy M Ribeiro; Hiroshi Mohri; David D Ho; Alan S Perelson
In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15572-7.
2002: Linqi Zhang; Wenjie Yu; Tian He; Jian Yu; Rebecca E Caffrey; Enrique A Dalmasso; Siyu Fu; Thang Pham; Jianfeng Mei; Jaclyn J Ho; Wenyong Zhang; Peter Lopez; David D Ho
Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor.
Science (New York, N.Y.) 2002;298(5595):995-1000.
2002: Sharon R Lewin; Glenn Heller; Linqi Zhang; Elaine Rodrigues; Eva Skulsky; Marcel R M van den Brink; Trudy N Small; Nancy A Kernan; Richard J O'Reilly; David D Ho; James W Young
Direct evidence for new T-cell generation by patients after either T-cell-depleted or unmodified allogeneic hematopoietic stem cell transplantations.
Blood 2002;100(6):2235-42.
2002: Martin Markowitz; Xia Jin; Arlene Hurley; Viviana Simon; Bharat Ramratnam; Michael Louie; Geoffrey R Deschenes; Murugappan Ramanathan; Shady Barsoum; Jeroen Vanderhoeven; Tian He; Chris Chung; John Murray; Alan S Perelson; Linqi Zhang; David D Ho
Discontinuation of antiretroviral therapy commenced early during the course of human immunodeficiency virus type 1 infection, with or without adjunctive vaccination.
The Journal of infectious diseases 2002;186(5):634-43.
2002: Linqi Zhang; Leslie Rowe; Tian He; Chris Chung; Jian Yu; Wenjie Yu; Andrew H Talal; Martin Markowitz; David D Ho
Compartmentalization of surface envelope glycoprotein of human immunodeficiency virus type 1 during acute and chronic infection.
Journal of virology 2002;76(18):9465-73.
2002: David D Ho; Yaoxing Huang
The HIV-1 vaccine race.
Cell 2002;110(2):135-8.
2002: Zhiwei Chen; Xiuqing Zhao; Yaoxing Huang; Agegnehu Gettie; Lei Ba; James Blanchard; David D Ho
CD4+ lymphocytopenia in acute infection of Asian macaques by a vaginally transmissible subtype-C, CCR5-tropic Simian/Human Immunodeficiency Virus (SHIV).
Journal of acquired immune deficiency syndromes (1999) 2002;30(2):133-45.
2002: Linqi Zhang; Peter J Dailey; Agegnehu Gettie; James Blanchard; David D Ho
The liver is a major organ for clearing simian immunodeficiency virus in rhesus monkeys.
Journal of virology 2002;76(10):5271-3.
2002: Ruy M Ribeiro; Hiroshi Mohri; David D Ho; Alan S Perelson
Modeling deuterated glucose labeling of T-lymphocytes.
Bulletin of mathematical biology 2002;64(2):385-405.
2002: Xia Jin; Murugappan Ramanathan; Shady Barsoum; Geoffrey R Deschenes; Lei Ba; James M Binley; Daryl Schiller; Daniel E Bauer; Donald C Chen; Arlene Hurley; Lucette Gebuhrer; Raphaelle El Habib; Pierre Caudrelier; Michel Klein; Linqi Zhang; David D Ho; Martin Markowitz
Safety and immunogenicity of ALVAC vCP1452 and recombinant gp160 in newly human immunodeficiency virus type 1-infected patients treated with prolonged highly active antiretroviral therapy.
Journal of virology 2002;76(5):2206-16.
2001: H Mohri; Alan S Perelson; K Tung; R M Ribeiro; Bharat Ramratnam; Martin Markowitz; Rhonda Kost; Arlene Hurley; L Weinberger; Denise Cesar; Marc K Hellerstein; David D Ho
Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy.
The Journal of experimental medicine 2001;194(9):1277-87.
2001: S Cherpelis; Xia Jin; Agegnehu Gettie; David D Ho; Susan W Barnett; I Shrivastava; Leonidas Stamatatos
DNA-immunization with a V2 deleted HIV-1 envelope elicits protective antibodies in macaques.
Immunology letters 2001;79(1-2):47-55.
2001: S Cherpelis; I Shrivastava; Agegnehu Gettie; Xia Jin; David D Ho; Susan W Barnett; Leonidas Stamatatos
DNA vaccination with the human immunodeficiency virus type 1 SF162DeltaV2 envelope elicits immune responses that offer partial protection from simian/human immunodeficiency virus infection to CD8(+) T-cell-depleted rhesus macaques.
Journal of virology 2001;75(3):1547-50.
2000: Linqi Zhang; Chris Chung; B S Hu; Tian He; Y Guo; A J Kim; Eva Skulsky; Xia Jin; Arlene Hurley; Bharat Ramratnam; Martin Markowitz; David D Ho
Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy.
The Journal of clinical investigation 2000;106(7):839-45.
2000: Xia Jin; Graham S Ogg; Sebastian Bonhoeffer; Jeffrey T Safrit; Mika S Vesanen; D Bauer; D Chen; Yunzhen Cao; MA Demoitie; Linqi Zhang; Martin Markowitz; D Nixon; A McMichael; David D Ho
An antigenic threshold for maintaining human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.
Molecular medicine (Cambridge, Mass.) 2000;6(9):803-9.
2000: Lisa A Chakrabarti; Sharon R Lewin; Linqi Zhang; Agegnehu Gettie; Amara Luckay; Louis N Martin; Eva Skulsky; David D Ho; Cecilia Cheng-Mayer; Preston A Marx
Age-dependent changes in T cell homeostasis and SIV load in sooty mangabeys.
Journal of medical primatology 2000;29(3-4):158-65.
2000: Zhiwei Chen; Yaoxing Huang; X Zhao; Eva Skulsky; D Lin; JE Ip; Agegnehu Gettie; David D Ho
Enhanced infectivity of an R5-tropic simian/human immunodeficiency virus carrying human immunodeficiency virus type 1 subtype C envelope after serial passages in pig-tailed macaques (Macaca nemestrina).
Journal of virology 2000;74(14):6501-10.
2000: Karin J Metzner; Xia Jin; F V Lee; Agegnehu Gettie; Daniel E Bauer; Michele Di Mascio; Alan S Perelson; Preston A Marx; David D Ho; Leondios G Kostrikis; Ruth I Connor
Effects of in vivo CD8(+) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.
The Journal of experimental medicine 2000;191(11):1921-31.
2000: Angelos Hatzakis; Giota Touloumi; Rose Karanicolas; Anastasia Karafoulidou; Titika Mandalaki; Cleo G Anastassopoulou; Linqi Zhang; James J Goedert; David D Ho; Leondios G Kostrikis
Effect of recent thymic emigrants on progression of HIV-1 disease.
Lancet 2000;355(9204):599-604.
2000: Lisa A Chakrabarti; Sharon R Lewin; Linqi Zhang; Agegnehu Gettie; Amara Luckay; Louis N Martin; Eva Skulsky; David D Ho; Cecilia Cheng-Mayer; Preston A Marx
Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection.
Journal of virology 2000;74(3):1209-23.
2000: Bharat Ramratnam; J E Mittler; Linqi Zhang; Daniel Boden; Arlene Hurley; F Fang; CA Macken; Alan S Perelson; Martin Markowitz; David D Ho
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy.
Nature medicine 2000;6(1):82-5.
1999: Leondios G Kostrikis; Avidan U Neumann; B Thomson; Bette T Korber; P McHardy; Rose Karanicolas; L Deutsch; Yaoxing Huang; J F Lew; K McIntosh; Henry Pollack; William Borkowsky; Hans M L Spiegel; Paul Palumbo; James M Oleske; Arlene Bardeguez; Katherine Luzuriaga; John L Sullivan; Steven Wolinsky; RA Koup; David D Ho; John P Moore
A polymorphism in the regulatory region of the CC-chemokine receptor 5 gene influences perinatal transmission of human immunodeficiency virus type 1 to African-American infants.
Journal of virology 1999;73(12):10264-71.
1999: Bharat Ramratnam; Sebastian Bonhoeffer; James M Binley; Arlene Hurley; Linqi Zhang; J E Mittler; Martin Markowitz; J P Moore; Alan S Perelson; David D Ho
Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis.
Lancet 1999;354(9192):1782-5.
1999: Linqi Zhang; Sharon R Lewin; Martin Markowitz; H H Lin; Eva Skulsky; Rose Karanicolas; Y He; Xia Jin; SE Tuttleton; Mika S Vesanen; Hans M L Spiegel; Rhonda Kost; Jan van Lunzen; Hans-Jürgen Stellbrink; Steven Wolinsky; William Borkowsky; Paul Palumbo; Leondios G Kostrikis; David D Ho
Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy.
The Journal of experimental medicine 1999;190(5):725-32.
1999: G M Ortiz; Douglas F Nixon; Alexandra Trkola; James M Binley; Xia Jin; Sebastian Bonhoeffer; P J Kuebler; Sean M Donahoe; MA Demoitie; WM Kakimoto; Thomas J Ketas; BA Clas; J J Heymann; Linqi Zhang; Yunzhen Cao; Arlene Hurley; John P Moore; David D Ho; Martin Markowitz
HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy.
The Journal of clinical investigation 1999;104(6):R13-8.
1999: J E Mittler; Martin Markowitz; David D Ho; Alan S Perelson
Improved estimates for HIV-1 clearance rate and intracellular delay.
AIDS (London, England) 1999;13(11):1415-7.
1999: Sharon R Lewin; Mika S Vesanen; Leondios G Kostrikis; Arlene Hurley; M Duran; Linqi Zhang; David D Ho; Martin Markowitz
Use of real-time PCR and molecular beacons to detect virus replication in human immunodeficiency virus type 1-infected individuals on prolonged effective antiretroviral therapy.
Journal of virology 1999;73(7):6099-103.
1999: Linqi Zhang; Bharat Ramratnam; Klara Tenner-Racz; Y He; Mika S Vesanen; S Lewin; Andrew H Talal; Paul Racz; Alan S Perelson; Bette T Korber; Martin Markowitz; David D Ho
Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.
The New England journal of medicine 1999;340(21):1605-13.
1999: Xia Jin; Daniel E Bauer; SE Tuttleton; S Lewin; Agegnehu Gettie; James Blanchard; C E Irwin; Jeffrey T Safrit; J Mittler; L Weinberger; Leondios G Kostrikis; Linqi Zhang; Alan S Perelson; David D Ho
Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.
The Journal of experimental medicine 1999;189(6):991-8.
1999: Douglas F Nixon; D Douek; P J Kuebler; Xia Jin; Mika S Vesanen; Sebastian Bonhoeffer; Yunzhen Cao; RA Koup; David D Ho; Martin Markowitz
Molecular tracking of an Human Immunodeficiency Virus nef specific cytotoxic T-cell clone shows persistence of clone-specific T-cell receptor DNA but not mRNA following early combination antiretroviral therapy.
Immunology letters 1999;66(1-3):219-28.
1999: Martin Markowitz; Mika S Vesanen; Klara Tenner-Racz; Yunzhen Cao; James M Binley; Andrew H Talal; Arlene Hurley; Xia Jin; M R Chaudhry; M Yaman; S Frankel; ME Heath-Chiozzi; JM Leonard; John P Moore; Paul Racz; Douglas F Nixon; David D Ho; X J
The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses.
The Journal of infectious diseases 1999;179(3):527-37.
1999: Linqi Zhang; Peter J Dailey; Tian He; Agegnehu Gettie; Sebastian Bonhoeffer; Alan S Perelson; David D Ho
Rapid clearance of simian immunodeficiency virus particles from plasma of rhesus macaques.
Journal of virology 1999;73(1):855-60.
1999: Graham S Ogg; X Jin; Sebastian Bonhoeffer; P Moss; M A Nowak; SP Monard; J P Segal; Yunzhen Cao; Sarah L Rowland-Jones; Arlene Hurley; MH Markowitz; David D Ho; Andrew J McMichael; Douglas F Nixon
Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy.
Journal of virology 1999;73(1):797-800.
1998: Zhiwei Chen; D Kwon; Z Jin; SP Monard; Paul Telfer; M S Jones; C Y Lu; R F Aguilar; David D Ho; Preston A Marx
Natural infection of a homozygous delta24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus.
The Journal of experimental medicine 1998;188(11):2057-65.
1998: X Jin; C G Roberts; D F Nixon; Yunzhen Cao; David D Ho; Bruce D Walker; Mark Muldoon; Bette T Korber; RA Koup
Longitudinal and cross-sectional analysis of cytotoxic T lymphocyte responses and their relationship to vertical human immunodeficiency virus transmission. ARIEL Project Investigators.
The Journal of infectious diseases 1998;178(5):1317-26.
1998: Linqi Zhang; Tian He; Yaoxing Huang; Zhiwei Chen; Y Guo; S Wu; Kevin Kunstman; R C Brown; J P Phair; Avidan U Neumann; David D Ho; Steven Wolinsky
Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1.
Journal of virology 1998;72(11):9307-12.
1998: Ruth I Connor; David C Montefiori; James M Binley; John P Moore; Sebastian Bonhoeffer; Agegnehu Gettie; E A Fenamore; KE Sheridan; David D Ho; Peter J Dailey; Preston A Marx
Temporal analyses of virus replication, immune responses, and efficacy in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.
Journal of virology 1998;72(9):7501-9.
1998: L Morris; James M Binley; BA Clas; Sebastian Bonhoeffer; T P Astill; Rhonda Kost; Arlene Hurley; Yunzhen Cao; Martin Markowitz; David D Ho; John P Moore
HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy.
The Journal of experimental medicine 1998;188(2):233-45.
1998: Leondios G Kostrikis; S Shin; David D Ho
Genotyping HIV-1 and HCV strains by a combinatorial DNA melting assay (COMA).
Molecular medicine (Cambridge, Mass.) 1998;4(7):443-53.
1998: Zhiwei Chen; Agegnehu Gettie; David D Ho; Preston A Marx
Primary SIVsm isolates use the CCR5 coreceptor from sooty mangabeys naturally infected in west Africa: a comparison of coreceptor usage of primary SIVsm, HIV-2, and SIVmac.
Virology 1998;246(1):113-24.
1998: David D Ho
Toward HIV eradication or remission: the tasks ahead.
Science (New York, N.Y.) 1998;280(5371):1866-7.
1998: Martin Markowitz; Marcus Conant; Arlene Hurley; Rosemary P Schluger; M Duran; J Peterkin; S Chapman; A Patick; A Hendricks; G J Yuen; W Hoskins; NJ Clendeninn; David D Ho
A preliminary evaluation of nelfinavir mesylate, an inhibitor of human immunodeficiency virus (HIV)-1 protease, to treat HIV infection.
The Journal of infectious diseases 1998;177(6):1533-40.
1998: Linqi Zhang; Tian He; Andrew H Talal; G Wang; Sarah Schlesinger Frankel; David D Ho
In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5.
Journal of virology 1998;72(6):5035-45.
1998: H Mo; SP Monard; Henry Pollack; JE Ip; Gemma Rochford; L Wu; JA Hoxie; William Borkowsky; David D Ho; John P Moore
Expression patterns of the HIV type 1 coreceptors CCR5 and CXCR4 on CD4+ T cells and monocytes from cord and adult blood.
AIDS research and human retroviruses 1998;14(7):607-17.
1998: James M Binley; Xia Jin; Yaoxing Huang; Linqi Zhang; Yunzhen Cao; David D Ho; John P Moore
Persistent antibody responses but declining cytotoxic T-lymphocyte responses to multiple human immunodeficiency virus type 1 antigens in a long-term nonprogressing individual with a defective p17 proviral sequence and no detectable viral RNA expression.
Journal of virology 1998;72(4):3472-4.
1998: Graham S Ogg; X Jin; Sebastian Bonhoeffer; P R Dunbar; M A Nowak; SP Monard; J P Segal; Yunzhen Cao; Sarah L Rowland-Jones; Vincenzo Cerundolo; Arlene Hurley; MH Markowitz; David D Ho; Douglas F Nixon; Andrew J McMichael
Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.
Science (New York, N.Y.) 1998;279(5359):2103-6.
1998: Leondios G Kostrikis; Yaoxing Huang; John P Moore; Steven Wolinsky; Linqi Zhang; Y Guo; L Deutsch; J Phair; Avidan U Neumann; David D Ho
A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation.
Nature medicine 1998;4(3):350-3.
1998: Leondios G Kostrikis; Sanjay Tyagi; Musa M Mhlanga; David D Ho; Fred Kramer
Spectral genotyping of human alleles.
Science (New York, N.Y.) 1998;279(5354):1228-9.
1998: Hiroshi Mohri; Sebastian Bonhoeffer; SP Monard; Alan S Perelson; David D Ho
Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.
Science (New York, N.Y.) 1998;279(5354):1223-7.
1998: T Zhu; Bette T Korber; A J Nahmias; E Hooper; P M Sharp; David D Ho
An African HIV-1 sequence from 1959 and implications for the origin of the epidemic.
Nature 1998;391(6667):594-7.
1998: Ruth I Connor; Bette T Korber; Barney S Graham; B H Hahn; David D Ho; B D Walker; Avidan U Neumann; Sten Vermund; J Mestecky; S Jackson; E Fenamore; Yunzhen Cao; F Gao; S Kalams; Kevin Kunstman; D McDonald; N McWilliams; Alexandra Trkola; John P Moore; Steven Wolinsky
Immunological and virological analyses of persons infected by human immunodeficiency virus type 1 while participating in trials of recombinant gp120 subunit vaccines.
Journal of virology 1998;72(2):1552-76.
1998: Y Huang; Linqi Zhang; David D Ho
Characterization of gag and pol sequences from long-term survivors of human immunodeficiency virus type 1 infection.
Virology 1998;240(1):36-49.
1997: Linqi Zhang; C D Carruthers; Tian He; Yaoxing Huang; Yunzhen Cao; G Wang; B Hahn; David D Ho
HIV type 1 subtypes, coreceptor usage, and CCR5 polymorphism.
AIDS research and human retroviruses 1997;13(16):1357-66.
1997: Melissa Pope; Sarah Schlesinger Frankel; John R Mascola; Alexandra Trkola; F Isdell; Deborah L Birx; Donald S. Burke; David D Ho; John P Moore
Human immunodeficiency virus type 1 strains of subtypes B and E replicate in cutaneous dendritic cell-T-cell mixtures without displaying subtype-specific tropism.
Journal of virology 1997;71(10):8001-7.
1997: Mika S Vesanen; Martin Markowitz; Yunzhen Cao; David D Ho; K Saksela
Human immunodeficiency virus type-1 mRNA splicing pattern in infected persons is determined by the proportion of newly infected cells.
Virology 1997;236(1):104-9.
1997: H Mo; Leonidas Stamatatos; JE Ip; C F Barbas; Paul W H I Parren; Dennis R Burton; John P Moore; David D Ho
Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. off.
Journal of virology 1997;71(9):6869-74.
1997: Linqi Zhang; Yaoxing Huang; H Yuan; B K Chen; JE Ip; David D Ho
Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection.
Journal of virology 1997;71(7):5608-13.
1997: David D Ho
Perspectives series: host/pathogen interactions. Dynamics of HIV-1 replication in vivo.
The Journal of clinical investigation 1997;99(11):2565-7.
1997: Alan S Perelson; P Essunger; Yunzhen Cao; Mika S Vesanen; Arlene Hurley; K Saksela; Martin Markowitz; David D Ho
Decay characteristics of HIV-1-infected compartments during combination therapy.
Nature 1997;387(6629):188-91.
1997: Yunzhen Cao; Paul Krogstad; Bette T Korber; RA Koup; Mark Muldoon; CA Macken; J L Song; Z Jin; J Q Zhao; S Clapp; I S Chen; David D Ho; Arthur J Ammann
Maternal HIV-1 viral load and vertical transmission of infection: the Ariel Project for the prevention of HIV transmission from mother to infant.
Nature medicine 1997;3(5):549-52.
1997: Zhiwei Chen; Amara Luckay; Donald L Sodora; Paul Telfer; P Reed; Agegnehu Gettie; J M Kanu; R F Sadek; J Yee; David D Ho; Linqi Zhang; Preston A Marx
Human immunodeficiency virus type 2 (HIV-2) seroprevalence and characterization of a distinct HIV-2 genetic subtype from the natural range of simian immunodeficiency virus-infected sooty mangabeys.
Journal of virology 1997;71(5):3953-60.
1997: James M Binley; P J Klasse; Yunzhen Cao; I Jones; Martin Markowitz; David D Ho; John P Moore
Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1.
Journal of virology 1997;71(4):2799-809.
1997: Zhiwei Chen; P Zhou; David D Ho; Nathaniel R Landau; Preston A Marx
Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry.
Journal of virology 1997;71(4):2705-14.
1997: Linqi Zhang; Ricardo Sobhie Diaz; David D Ho; James W Mosley; Michael P Busch; A Mayer
Host-specific driving force in human immunodeficiency virus type 1 evolution in vivo.
Journal of virology 1997;71(3):2555-61.
1997: Linqi Zhang; Y Huang; H Yuan; SE Tuttleton; David D Ho
Genetic characterization of vif, vpr, and vpu sequences from long-term survivors of human immunodeficiency virus type 1 infection.
Virology 1997;228(2):340-9.
1997: Linqi Zhang; Yaoxing Huang; H Yuan; B K Chen; JE Ip; David D Ho
Identification of a replication-competent pathogenic human immunodeficiency virus type 1 with a duplication in the TCF-1alpha region but lacking NF-kappaB binding sites.
Journal of virology 1997;71(2):1651-6.
1997: Alan S Perelson; P Essunger; David D Ho
Dynamics of HIV-1 and CD4+ lymphocytes in vivo.
AIDS (London, England) 1997;11 Suppl A():S17-24.
1996: Leondios G Kostrikis; Z H Michalopoulou; Yunzhen Cao; J P Moore; David D Ho
Determining neutralization serotypes of HIV type 1 by neural networks.
AIDS research and human retroviruses 1996;12(18):1667-9.
1996: Yaoxing Huang; William A Paxton; Steven Wolinsky; Avidan U Neumann; Linqi Zhang; Tian He; S Kang; D Ceradini; Z Jin; K Yazdanbakhsh; Kevin Kunstman; D Erickson; E Dragon; Nathaniel R Landau; John Phair; David D Ho; RA Koup
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.
Nature medicine 1996;2(11):1240-3.
1996: Preston A Marx; A I Spira; Agegnehu Gettie; Peter J Dailey; Ronald S Veazey; Andrew Lackner; C J Mahoney; Christopher J Miller; L E Claypool; David D Ho; N J Alexander
Progesterone implants enhance SIV vaginal transmission and early virus load.
Nature medicine 1996;2(10):1084-9.
1996: Jaap Goudsmit; Anthony de Ronde; David D Ho; A S Perelson
Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase.
Journal of virology 1996;70(8):5662-4.
1996: Ruth I Connor; K E Sheridan; C Lai; Linqi Zhang; David D Ho
Characterization of the functional properties of env genes from long-term survivors of human immunodeficiency virus type 1 infection.
Journal of virology 1996;70(8):5306-11.
1996: Akhteruzzaman Molla; M Korneyeva; Q Gao; Sudthida Vasavanonda; P J Schipper; H M Mo; Martin Markowitz; T Chernyavskiy; P Niu; N Lyons; Ann Hsu; G Richard Granneman; David D Ho; Charles A B Boucher; J M Leonard; Daniel W Norbeck; Dale J Kempf
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir.
Nature medicine 1996;2(7):760-6.
1996: Y Cao; L Qin; Linqi Zhang; J Safrit; David D Ho
Characterization of long-term survivors of human immunodeficiency virus type 1 infection.
Immunology letters 1996;51(1-2):7-13.
1996: Zhiwei Chen; P Telfier; Agegnehu Gettie; P Reed; Linqi Zhang; David D Ho; Preston A Marx
Genetic characterization of new West African simian immunodeficiency virus SIVsm: geographic clustering of household-derived SIV strains with human immunodeficiency virus type 2 subtypes and genetically diverse viruses from a single feral sooty mangabey troop.
Journal of virology 1996;70(6):3617-27.
1996: David D Ho
Viral counts count in HIV infection.
Science (New York, N.Y.) 1996;272(5265):1124-5.
1996: T Zhu; N Wang; A Carr; D S Nam; R Moor-Jankowski; D A Cooper; David D Ho
Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission.
Journal of virology 1996;70(5):3098-107.
1996: Steven Wolinsky; B T Korber; Avidan U Neumann; M Daniels; Kevin Kunstman; A J Whetsell; Manohar R Furtado; Yunzhen Cao; David D Ho; J T Safrit
Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection.
Science (New York, N.Y.) 1996;272(5261):537-42.
1996: Alan S Perelson; A U Neumann; Martin Markowitz; J M Leonard; David D Ho
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time.
Science (New York, N.Y.) 1996;271(5255):1582-6.
1996: H Mo; Martin Markowitz; P Majer; S K Burt; Sergei V Gulnik; L I Suvorov; John W Erickson; David D Ho
Design, synthesis, and resistance patterns of MP-134 and MP-167, two novel inhibitors of HIV type 1 protease.
AIDS research and human retroviruses 1996;12(1):55-61.
1996: A I Spira; Preston A Marx; Bruce K Patterson; J Mahoney; RA Koup; Steven Wolinsky; David D Ho
Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques.
The Journal of experimental medicine 1996;183(1):215-25.
1996: L G Kostrikis; Y Cao; H Ngai; J P Moore; David D Ho
Quantitative analysis of serum neutralization of human immunodeficiency virus type 1 from subtypes A, B, C, D, E, F, and I: lack of direct correlation between neutralization serotypes and genetic subtypes and evidence for prevalent serum-dependent infectivity enhancement.
Journal of virology 1996;70(1):445-58.
1996: J P Moore; Y Cao; J Leu; L Qin; B Korber; David D Ho
Inter- and intraclade neutralization of human immunodeficiency virus type 1: genetic clades do not correspond to neutralization serotypes but partially correspond to gp120 antigenic serotypes.
Journal of virology 1996;70(1):427-44.
1995: Y Huang; Linqi Zhang; David D Ho
Biological characterization of nef in long-term survivors of human immunodeficiency virus type 1 infection.
Journal of virology 1995;69(12):8142-6.
1995: Alexandra Trkola; A B Pomales; H Yuan; B Korber; Paul J Maddon; G P Allaway; Hermann Katinger; Carlos F Barbas; Dennis R Burton; David D Ho
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.
Journal of virology 1995;69(11):6609-17.
1995: L G Kostrikis; E Bagdades; Y Cao; Linqi Zhang; D Dimitriou; David D Ho
Genetic analysis of human immunodeficiency virus type 1 strains from patients in Cyprus: identification of a new subtype designated subtype I.
Journal of virology 1995;69(10):6122-30.
1995: David D Ho
HIV-1 dynamics in vivo.
Journal of biological regulators and homeostatic agents 1995;9(3):76-7.
1995: M Reedijk; Charles A B Boucher; Toon van Bommel; David D Ho; T B Tzeng; D Sereni; P Veyssier; Suzanne Jurriaans; Richard G Granneman; Ann Hsu
Safety, pharmacokinetics, and antiviral activity of A77003, a C2 symmetry-based human immunodeficiency virus protease inhibitor.
Antimicrobial agents and chemotherapy 1995;39(7):1559-64.
1995: Zhiwei Chen; Paul Telfer; P Reed; Linqi Zhang; A Getti; David D Ho; Preston A Marx
Isolation and characterization of the first simian immunodeficiency virus from a feral sooty mangabey (Cercocebus atys) in West Africa.
Journal of medical primatology 1995;24(3):108-15.
1995: N Wang; T Zhu; David D Ho
Sequence diversity of V1 and V2 domains of gp120 from human immunodeficiency virus type 1: lack of correlation with viral phenotype.
Journal of virology 1995;69(4):2708-15.
1995: Y Cao; David D Ho; J Todd; R Kokka; M Urdea; Jeffrey D Lifson; M Piatak; S Chen; Beatrice H Hahn; Michael S Saag
Clinical evaluation of branched DNA signal amplification for quantifying HIV type 1 in human plasma.
AIDS research and human retroviruses 1995;11(3):353-61.
1995: Martin Markowitz; H Mo; Dale J Kempf; Daniel W Norbeck; T N Bhat; John W Erickson; David D Ho
Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor.
Journal of virology 1995;69(2):701-6.
1995: T Zhu; N Wang; A Carr; Steven Wolinsky; David D Ho
Evidence for coinfection by multiple strains of human immunodeficiency virus type 1 subtype B in an acute seroconvertor.
Journal of virology 1995;69(2):1324-7.
1995: Y Cao; L Qin; Linqi Zhang; J Safrit; David D Ho
Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection.
The New England journal of medicine 1995;332(4):201-8.
1995: David D Ho; A U Neumann; Alan S Perelson; W Chen; J M Leonard; Martin Markowitz
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection.
Nature 1995;373(6510):123-6.
1995: J P Moore; David D Ho
HIV-1 neutralization: the consequences of viral adaptation to growth on transformed T cells.
AIDS (London, England) 1995;9 Suppl A():S117-36.
1995: Y Huang; Linqi Zhang; David D Ho
Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection.
Journal of virology 1995;69(1):93-100.
1995: A I Spira; David D Ho
Effect of different donor cells on human immunodeficiency virus type 1 replication and selection in vitro.
Journal of virology 1995;69(1):422-9.
1995: J P Moore; Alexandra Trkola; B Korber; L J Boots; J A Kessler; Francine E McCutchan; John R Mascola; David D Ho; J Robinson; Anthony J Conley
A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B.
Journal of virology 1995;69(1):122-30.
1995: J P Moore; Y Cao; L Qing; Quentin J Sattentau; J Pyati; R Koduri; J Robinson; Carlos F Barbas; Dennis R Burton; David D Ho
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
Journal of virology 1995;69(1):101-9.
1994: J P Moore; Francine E McCutchan; S W Poon; John R Mascola; J Liu; Y Cao; David D Ho
Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies.
Journal of virology 1994;68(12):8350-64.
1994: J P Moore; Y Cao; David D Ho; RA Koup
Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1.
Journal of virology 1994;68(8):5142-55.
1994: RA Koup; J T Safrit; Y Cao; C A Andrews; G McLeod; William Borkowsky; C Farthing; David D Ho
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome.
Journal of virology 1994;68(7):4650-5.
1994: Ruth I Connor; David D Ho
Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression.
Journal of virology 1994;68(7):4400-8.
1994: Ruth I Connor; David D Ho
Transmission and pathogenesis of human immunodeficiency virus type 1.
AIDS research and human retroviruses 1994;10(4):321-3.
1994: J P Moore; Y Cao; Anthony J Conley; R Wyatt; J Robinson; Miroslaw K Gorny; Susan Zolla-Pazner; David D Ho; RA Koup
Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays.
Journal of acquired immune deficiency syndromes 1994;7(4):332-9.
1994: David D Ho; T Toyoshima; H Mo; Dale J Kempf; Daniel W Norbeck; Chih-Ming Chen; Norman E Wideburg; S K Burt; John W Erickson; M K Singh
Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor.
Journal of virology 1994;68(3):2016-20.
1994: J T Safrit; C A Andrews; T Zhu; David D Ho; RA Koup
Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope.
The Journal of experimental medicine 1994;179(2):463-72.
1994: H Yoshiyama; H Mo; J P Moore; David D Ho
Characterization of mutants of human immunodeficiency virus type 1 that have escaped neutralization by a monoclonal antibody to the gp120 V2 loop.
Journal of virology 1994;68(2):974-8.
1993: J P Moore; H Yoshiyama; David D Ho; J E Robinson; Joseph Sodroski
Antigenic variation in gp120s from molecular clones of HIV-1 LAI.
AIDS research and human retroviruses 1993;9(12):1185-93.
1993: T Zhu; H Mo; N Wang; D S Nam; Y Cao; RA Koup; David D Ho
Genotypic and phenotypic characterization of HIV-1 patients with primary infection.
Science (New York, N.Y.) 1993;261(5125):1179-81.
1993: Ruth I Connor; D W Notermans; H Mohri; Y Cao; David D Ho
Biological cloning of functionally diverse quasispecies of HIV-1.
AIDS research and human retroviruses 1993;9(6):541-6.
1993: J P Moore; Linda C Burkly; Ruth I Connor; Y Cao; R Tizard; David D Ho; R A Fisher
Adaptation of two primary human immunodeficiency virus type 1 isolates to growth in transformed T cell lines correlates with alterations in the responses of their envelope glycoproteins to soluble CD4.
AIDS research and human retroviruses 1993;9(6):529-39.
1993: Ruth I Connor; H Mohri; Y Cao; David D Ho
Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals.
Journal of virology 1993;67(4):1772-7.
1993: J P Moore; David D Ho
Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans.
Journal of virology 1993;67(2):863-75.
1993: H Mohri; M K Singh; W T Ching; David D Ho
Quantitation of zidovudine-resistant human immunodeficiency virus type 1 in the blood of treated and untreated patients.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):25-9.
1992: David D Ho; M S Fung; H Yoshiyama; Y Cao; J E Robinson
Discontinuous epitopes on gp120 important in HIV-1 neutralization.
AIDS research and human retroviruses 1992;8(8):1337-9.
1992: S Pang; Y Shlesinger; Eric S Daar; T Moudgil; David D Ho; Irvin S Y Chen
Rapid generation of sequence variation during primary HIV-1 infection.
AIDS (London, England) 1992;6(5):453-60.
1992: William A O'Brien; Irvin S Y Chen; David D Ho; Eric S Daar
Mapping genetic determinants for human immunodeficiency virus type 1 resistance to soluble CD4.
Journal of virology 1992;66(5):3125-30.
1992: J P Defoort; B Nardelli; W Huang; David D Ho; James P Tam
Macromolecular assemblage in the design of a synthetic AIDS vaccine.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):3879-83.
1992: M S Fung; C R Sun; W L Gordon; R S Liou; T W Chang; W N Sun; E S Daar; David D Ho
Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120.
Journal of virology 1992;66(2):848-56.
1992: Y Z Cao; DT Dieterich; P A Thomas; Y X Huang; M Mirabile; David D Ho
Identification and quantitation of HIV-1 in the liver of patients with AIDS.
AIDS (London, England) 1992;6(1):65-70.
1991: David D Ho; M S Fung; Y Z Cao; X L Li; C Sun; T W Chang; N C Sun
Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibody.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):8949-52.
1991: W D Hardy; Eric S Daar; R T Sokolov; David D Ho
Acute neurologic deterioration in a young man.
Reviews of infectious diseases 1991;13(4):745-50.
1991: Eric S Daar; David D Ho
Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4.
The American journal of medicine 1991;90(4A):22S-26S.
1991: Eric S Daar; T Moudgil; R D Meyer; David D Ho
Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection.
The New England journal of medicine 1991;324(14):961-4.
1991: David D Ho; J A McKeating; X L Li; T Moudgil; Eric S Daar; N C Sun; J E Robinson
Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody.
Journal of virology 1991;65(1):489-93.
1990: Eric S Daar; X L Li; T Moudgil; David D Ho
High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6574-8.
1990: Y Z Cao; Alvin E Friedman-Kien; Y X Huang; X L Li; M Mirabile; T Moudgil; Dorothea Zucker-Franklin; David D Ho
CD4-independent, productive human immunodeficiency virus type 1 infection of hepatoma cell lines in vitro.
Journal of virology 1990;64(6):2553-9.
1990: X L Li; T Moudgil; Harry V Vinters; David D Ho
CD4-independent, productive infection of a neuronal cell line by human immunodeficiency virus type 1.
Journal of virology 1990;64(3):1383-7.
1990: Y Z Cao; Alvin E Friedman-Kien; M Mirabile; X L Li; M Alam; DT Dieterich; David D Ho
HIV-1 neutralizing antibodies in urine from seropositive individuals.
Journal of acquired immune deficiency syndromes 1990;3(3):195-9.
1989: David D Ho; Dale E Bredesen; Harry V Vinters; Eric S Daar
The acquired immunodeficiency syndrome (AIDS) dementia complex.
Annals of internal medicine 1989;111(5):400-10.
1989: N C Sun; David D Ho; C R Sun; R S Liou; W Gordon; M S Fung; X L Li; R C Ting; T H Lee; N T Chang
Generation and characterization of monoclonal antibodies to the putative CD4-binding domain of human immunodeficiency virus type 1 gp120.
Journal of virology 1989;63(9):3579-85.
1989: David D Ho; T Moudgil; H S Robin; M Alam; B J Wallace; Y Mizrachi
Human immunodeficiency virus type 1 in a seronegative patient with visceral Kaposi's sarcoma and hypogammaglobulinemia.
The American journal of medicine 1989;86(3):349-51.
1988: David D Ho; J C Kaplan; I E Rackauskas; M E Gurney
Second conserved domain of gp120 is important for HIV infectivity and antibody neutralization.
Science (New York, N.Y.) 1988;239(4843):1021-3.