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Daryl Hoban

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George G Zhanel; Heather J Adam; Melanie R Baxter; Andrew J Denisuik; Jeff Fuller; Daryl J Hoban; James A Karlowsky; Philippe R S Lagacé-Wiens; Kimberly A Nichol; Frank Schweizer; Andrew Walkty
Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007-11 study.
Andrew J Denisuik; Daryl J Hoban; James A Karlowsky; Philippe R S Lagacé-Wiens; Michael Mulvey; Johann D D Pitout; Patricia J Simner; Franil Tailor; George G Zhanel; Heather J Adam
Molecular epidemiology of extended-spectrum β-lactamase-, AmpC β-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae isolated from Canadian hospitals over a 5 year period: CANWARD 2007-11.
Kimberly A Nichol; Diane L Roscoe; George G Zhanel; Heather J Adam; George R Golding; Daryl J Hoban; Philippe R S Lagacé-Wiens
Changing epidemiology of methicillin-resistant Staphylococcus aureus in Canada.

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2013: George G Zhanel; Heather J Adam; Melanie R Baxter; Andrew J Denisuik; Jeff Fuller; Daryl J Hoban; James A Karlowsky; Philippe R S Lagacé-Wiens; Kimberly A Nichol; Frank Schweizer; Andrew Walkty
Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007-11 study.
The Journal of antimicrobial chemotherapy 2013;68 Suppl 1():i7-i22.
2013: Andrew J Denisuik; Daryl J Hoban; James A Karlowsky; Philippe R S Lagacé-Wiens; Michael Mulvey; Johann D D Pitout; Patricia J Simner; Franil Tailor; George G Zhanel; Heather J Adam
Molecular epidemiology of extended-spectrum β-lactamase-, AmpC β-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae isolated from Canadian hospitals over a 5 year period: CANWARD 2007-11.
The Journal of antimicrobial chemotherapy 2013;68 Suppl 1():i57-i65.
2013: Kimberly A Nichol; Diane L Roscoe; George G Zhanel; Heather J Adam; George R Golding; Daryl J Hoban; Philippe R S Lagacé-Wiens
Changing epidemiology of methicillin-resistant Staphylococcus aureus in Canada.
The Journal of antimicrobial chemotherapy 2013;68 Suppl 1():i47-i55.
2013: James A Karlowsky; Philippe R S Lagacé-Wiens; George G Zhanel; Heather J Adam; Marc Desjardins; Daryl J Hoban
Changes in fluoroquinolone resistance over 5 years (CANWARD 2007-11) in bacterial pathogens isolated in Canadian hospitals.
The Journal of antimicrobial chemotherapy 2013;68 Suppl 1():i39-i46.
2013: Heather J Adam; Melanie R Baxter; Ross J Davidson; Sergio Fanella; Daryl J Hoban; James A Karlowsky; Philippe R S Lagacé-Wiens; Ethan Rubinstein; George G Zhanel
Comparison of pathogens and their antimicrobial resistance patterns in paediatric, adult and elderly patients in Canadian hospitals.
The Journal of antimicrobial chemotherapy 2013;68 Suppl 1():i31-i37.
2013: Philippe R S Lagacé-Wiens; Donald E Low; Michael R Mulvey; Kimberly A Nichol; Andrew Walkty; George G Zhanel; Heather J Adam; Melanie R Baxter; Joseph M Blondeau; Andrew J Denisuik; Daryl J Hoban; James A Karlowsky
Trends in antibiotic resistance over time among pathogens from Canadian hospitals: results of the CANWARD study 2007-11.
The Journal of antimicrobial chemotherapy 2013;68 Suppl 1():i23-i29.
2013: Sibylle H Lob; Robert E Badal; Samuel K Bouchillon; Meredith A Hackel; Stephen P Hawser; Daryl J Hoban
Epidemiology and Susceptibility of Gram-Negative Appendicitis Pathogens: SMART 2008-2010.
Surgical infections 2013;14(2):203-8.
2013: Stephen P Hawser; Daryl J Hoban; Robert E Badal; Douglas J Biedenbach; Samuel K Bouchillon; Rafael Cantón; David L Paterson
Monitoring the global in vitro activity of ertapenem against Escherichia coli from intra-abdominal infections: SMART 2002-2010.
International journal of antimicrobial agents 2013;41(3):224-8.
2013: George G Zhanel; Heather Adam; Andrew Denisuik; Alfred Gin; Daryl J Hoban; Philippe R S Lagacé-Wiens; Christopher D Lawson; Joseph P Lynch; Ethan Rubinstein; Frank Schweizer; Sheryl A Zelenitsky; James A Karlowsky
Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor combination.
Drugs 2013;73(2):159-77.
2012: Daryl J Hoban; Christine Lascols; Lindsay E Nicolle; Robert Badal; Samuel K Bouchillon; Meredith Hackel; Stephen Hawser
Antimicrobial susceptibility of Enterobacteriaceae, including molecular characterization of extended-spectrum beta-lactamase-producing species, in urinary tract isolates from hospitalized patients in North America and Europe: results from the SMART study 2009-2010.
Diagnostic microbiology and infectious disease 2012;74(1):62-7.
2012: Andrew Walkty; Heather Adam; Melanie Baxter; Daryl J Hoban; James A Karlowsky; Philippe R S Lagacé-Wiens; George G Zhanel
Antimicrobial susceptibility of Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals: CANWARD 2008-2011.
Diagnostic microbiology and infectious disease 2012;73(4):361-4.
2012: George G Zhanel; Heather Adam; Daryl J Hoban; Kim Nichol; Ayman Noreddin; Chris Yachison; James A Karlowsky
Assessment of the activity of ceftaroline against clinical isolates of penicillin-intermediate and penicillin-resistant Streptococcus pneumoniae with elevated MICs of ceftaroline using an in vitro pharmacodynamic model.
The Journal of antimicrobial chemotherapy 2012;67(7):1706-11.
2012: Christine Lascols; Steven H Marshall; Robert E Badal; Samuel K Bouchillon; Meredith Hackel; Stephen P Hawser; Daryl J Hoban; Andrea Hujer; Robert A Bonomo
Using nucleic acid microarrays to perform molecular epidemiology and detect novel β-lactamases: a snapshot of extended-spectrum β-lactamases throughout the world.
Journal of clinical microbiology 2012;50(5):1632-9.
2012: George G Zhanel; Heather Adam; Brandon Findlay; Alfred Gin; Daryl J Hoban; Christopher D Lawson; Joseph P Lynch; Ethan Rubinstein; Frank Schweizer; Andrew Walkty; Sheryl A Zelenitsky; James A Karlowsky
Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin.
Expert review of anti-infective therapy 2012;10(4):459-73.
2012: Heather J Adam; Joanne Embree; Matthew W Gilmour; Daryl J Hoban; James A Karlowsky; Kimberly A Nichol; George G Zhanel
Baseline epidemiology of Streptococcus pneumoniae serotypes in Canada prior to the introduction of the 13-valent pneumococcal vaccine.
Microbial drug resistance (Larchmont, N.Y.) 2012;18(2):176-82.
2012: James A Karlowsky; Andrew J Walkty; Heather J Adam; Melanie R Baxter; Daryl J Hoban; George G Zhanel
Prevalence of antimicrobial resistance among clinical isolates of Bacteroides fragilis group in Canada in 2010-2011: CANWARD surveillance study.
Antimicrobial agents and chemotherapy 2012;56(3):1247-52.
2012: Stephen P Hawser; Daryl J Hoban; Christine A Lascols; Robert E Badal; Samuel K Bouchillon; Meredith A Hackel; Maria V Villegas; Flavia Rossi
Low frequency of ertapenem-resistant intra-abdominal isolates of Escherichia coli from Latin America: susceptibility, ESBL-occurrence, and molecular characterisation (SMART 2008-2009).
Journal of chemotherapy (Florence, Italy) 2012;24(1):6-11.
2012: Samuel K Bouchillon; Robert Badal; Daryl J Hoban; Stephen Hawser
Fluoroquinolone resistance among gram-negative urinary tract pathogens: global smart program results, 2009-2010.
The open microbiology journal 2012;6():74-8.
2011: Patricia J Simner; George G Zhanel; Daryl J Hoban; Philippe R S Lagacé-Wiens; James A Karlowsky
Fluoroquinolone resistance in Escherichia coli isolated from patients attending Canadian hospitals is associated with the ST131 clone.
Diagnostic microbiology and infectious disease 2011;71(3):323-4.
2011: Daryl J Hoban; Lindsay E Nicolle; Samuel K Bouchillon; Stephen Hawser; Robert Badal
Antimicrobial susceptibility of global inpatient urinary tract isolates of Escherichia coli: results from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program: 2009-2010.
Diagnostic microbiology and infectious disease 2011;70(4):507-11.
2011: James A Karlowsky; Philippe R S Lagacé-Wiens; Patricia J Simner; Andrew Walkty; Heather J Adam; Melanie R DeCorby; Daryl J Hoban; George G Zhanel
Antimicrobial resistance in urinary tract pathogens in Canada from 2007 to 2009: CANWARD surveillance study.
Antimicrobial agents and chemotherapy 2011;55(7):3169-75.
2011: George G Zhanel; Emma Rossnagel; Kim Nichol; Lauren Cox; James A Karlowsky; Sheryl A Zelenitsky; Ayman Noreddin; Daryl J Hoban
Ceftaroline pharmacodynamic activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model.
The Journal of antimicrobial chemotherapy 2011;66(6):1301-5.
2011: James A Karlowsky; Heather J Adam; Melanie R DeCorby; Philippe R S Lagacé-Wiens; Daryl J Hoban; George G Zhanel
In vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients in Canadian hospitals in 2009.
Antimicrobial agents and chemotherapy 2011;55(6):2837-46.
2011: Philippe R S Lagacé-Wiens; F Tailor; P Simner; Melanie R DeCorby; James A Karlowsky; Andrew Walkty; Daryl J Hoban; George G Zhanel
Activity of NXL104 in combination with beta-lactams against genetically characterized Escherichia coli and Klebsiella pneumoniae isolates producing class A extended-spectrum beta-lactamases and class C beta-lactamases.
Antimicrobial agents and chemotherapy 2011;55(5):2434-7.
2011: Yen-Hsu Chen; Po-Ren Hsueh; Robert E Badal; Stephen P Hawser; Daryl J Hoban; Samuel K Bouchillon; Yuxing Ni; David L Paterson
Antimicrobial susceptibility profiles of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections in the Asia-Pacific region according to currently established susceptibility interpretive criteria.
The Journal of infection 2011;62(4):280-91.
2011: Andrew Walkty; Heather J Adam; Michel Laverdière; James A Karlowsky; Daryl J Hoban; George G Zhanel
In vitro activity of ceftobiprole against frequently encountered aerobic and facultative Gram-positive and Gram-negative bacterial pathogens: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):348-55.
2011: James A Karlowsky; Heather J Adam; Susan M Poutanen; Daryl J Hoban; George G Zhanel
In vitro activity of dalbavancin and telavancin against staphylococci and streptococci isolated from patients in Canadian hospitals: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):342-7.
2011: Melissa McCracken; Laura F Mataseje; Vivian Loo; Andrew Walkty; Heather J Adam; Daryl J Hoban; George G Zhanel; Michael Mulvey
Characterization of Acinetobacter baumannii and meropenem-resistant Pseudomonas aeruginosa in Canada: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):335-41.
2011: Patricia J Simner; George G Zhanel; Johann Pitout; Franil Tailor; Melissa McCracken; Michael Mulvey; Philippe R S Lagacé-Wiens; Heather J Adam; Daryl J Hoban
Prevalence and characterization of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Escherichia coli: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):326-34.
2011: Kimberly A Nichol; Heather J Adam; Zafar Hussain; Michael Mulvey; Melissa McCracken; Laura F Mataseje; Kristjan Thompson; Sara Kost; Philippe R S Lagacé-Wiens; Daryl J Hoban; George G Zhanel
Comparison of community-associated and health care-associated methicillin-resistant Staphylococcus aureus in Canada: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):320-5.
2011: Philippe R S Lagacé-Wiens; Patricia J Simner; Kevin R Forward; Franil Tailor; Heather J Adam; Melanie R DeCorby; James A Karlowsky; Daryl J Hoban; George G Zhanel
Analysis of 3789 in- and outpatient Escherichia coli isolates from across Canada--results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):314-9.
2011: Heather J Adam; Melanie R DeCorby; Robert Rennie; James A Karlowsky; Daryl J Hoban; George G Zhanel
Prevalence of antimicrobial resistant pathogens from blood cultures from Canadian hospitals: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):307-13.
2011: George G Zhanel; Heather J Adam; Donald E Low; Joseph Blondeau; Melanie R DeCorby; James A Karlowsky; Barbara Weshnoweski; Ravi Vashisht; Aleksandra Wierzbowski; Daryl J Hoban
Antimicrobial susceptibility of 15,644 pathogens from Canadian hospitals: results of the CANWARD 2007-2009 study.
Diagnostic microbiology and infectious disease 2011;69(3):291-306.
2011: Daryl J Hoban; George G Zhanel
Introduction to the CANWARD Study (2007-2009).
Diagnostic microbiology and infectious disease 2011;69(3):289-90.
2011: Stephen P Hawser; Samuel K Bouchillon; Daryl J Hoban; Michael Dowzicky; Tim Babinchak
Rising incidence of Staphylococcus aureus with reduced susceptibility to vancomycin and susceptibility to antibiotics: a global analysis 2004-2009.
International journal of antimicrobial agents 2011;37(3):219-24.
2011: S Hawser; Daryl J Hoban; Samuel K Bouchillon; R Badal; Y Carmeli; P Hawkey
Antimicrobial susceptibility of intra-abdominal gram-negative bacilli from Europe: SMART Europe 2008.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2011;30(2):173-9.
2010: George G Zhanel; Melanie R DeCorby; Heather J Adam; Michael Mulvey; Melissa McCracken; Philippe R S Lagacé-Wiens; Kimberly A Nichol; Aleksandra Wierzbowski; Patricia J Baudry; Franil Tailor; James A Karlowsky; Andrew Walkty; Frank Schweizer; Jack Johnson; Daryl J Hoban
Prevalence of antimicrobial-resistant pathogens in Canadian hospitals: results of the Canadian Ward Surveillance Study (CANWARD 2008).
Antimicrobial agents and chemotherapy 2010;54(11):4684-93.
2010: Po-Ren Hsueh; Robert E Badal; Stephen P Hawser; Daryl J Hoban; Samuel K Bouchillon; Yuxing Ni; David L Paterson
Epidemiology and antimicrobial susceptibility profiles of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections in the Asia-Pacific region: 2008 results from SMART (Study for Monitoring Antimicrobial Resistance Trends).
International journal of antimicrobial agents 2010;36(5):408-14.
2010: Stephen P Hawser; Robert E Badal; Samuel K Bouchillon; Daryl J Hoban; Po-Ren Hsueh
Comparison of CLSI 2009, CLSI 2010 and EUCAST cephalosporin clinical breakpoints in recent clinical isolates of Escherichia coli, Klebsiella pneumoniae and Klebsiella oxytoca from the SMART Global Surveillance Study.
International journal of antimicrobial agents 2010;36(3):293-4.
2010: Stephen P Hawser; Robert E Badal; Samuel K Bouchillon; Daryl J Hoban
Antibiotic susceptibility of intra-abdominal infection isolates from Indian hospitals during 2008.
Journal of medical microbiology 2010;59(Pt 9):1050-4.
2010: Stephen P Hawser; Samuel K Bouchillon; Daryl J Hoban; Robert E Badal
Epidemiologic trends, occurrence of extended-spectrum beta-lactamase production, and performance of ertapenem and comparators in patients with intra-abdominal infections: analysis of global trend data from 2002-2007 from the SMART study.
Surgical infections 2010;11(4):371-8.
2010: Daryl J Hoban; Samuel K Bouchillon; Stephen P Hawser; Robert E Badal; Vincent J Labombardi; Joseph DiPersio
Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART).
Antimicrobial agents and chemotherapy 2010;54(7):3031-4.
2010: Stephen P Hawser; Samuel K Bouchillon; Daryl J Hoban; Robert E Badal; Rafael Cantón; Fernando Baquero
Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrobial Resistance Trends (SMART).
Antimicrobial agents and chemotherapy 2010;54(7):3043-6.
2010: George G Zhanel; Divna Calic; Frank Schweizer; Sheryl A Zelenitsky; Heather Adam; Philippe R S Lagacé-Wiens; Ethan Rubinstein; Alfred Gin; Daryl J Hoban; James A Karlowsky
New lipoglycopeptides: a comparative review of dalbavancin, oritavancin and telavancin.
Drugs 2010;70(7):859-86.
2010: Daryl J Hoban; Samuel K Bouchillon; Stephen P Hawser; Robert E Badal
Trends in the frequency of multiple drug-resistant Enterobacteriaceae and their susceptibility to ertapenem, imipenem, and other antimicrobial agents: data from the Study for Monitoring Antimicrobial Resistance Trends 2002 to 2007.
Diagnostic microbiology and infectious disease 2010;66(1):78-86.
2009: Patricia J Baudry; Laura Mataseje; George G Zhanel; Daryl J Hoban; Michael Mulvey
Characterization of plasmids encoding CMY-2 AmpC beta-lactamases from Escherichia coli in Canadian intensive care units.
Diagnostic microbiology and infectious disease 2009;65(4):379-83.
2009: Stephen P Hawser; Samuel K Bouchillon; Daryl J Hoban; Robert E Badal
In vitro susceptibilities of aerobic and facultative anaerobic Gram-negative bacilli from patients with intra-abdominal infections worldwide from 2005-2007: results from the SMART study.
International journal of antimicrobial agents 2009;34(6):585-8.
2009: Heather J Adam; Nancy M Laing; C Richard King; Ben Lulashnyk; Daryl J Hoban; George G Zhanel
In vitro activity of nemonoxacin, a novel nonfluorinated quinolone, against 2,440 clinical isolates.
Antimicrobial agents and chemotherapy 2009;53(11):4915-20.
2009: George G Zhanel; Patricia J Baudry; Franil Tailor; Lauren Cox; Daryl J Hoban; James A Karlowsky
Determination of the pharmacodynamic activity of clinically achievable tigecycline serum concentrations against clinical isolates of Escherichia coli with extended-spectrum beta-lactamases, AmpC beta-lactamases and reduced susceptibility to carbapenems using an in vitro model.
The Journal of antimicrobial chemotherapy 2009;64(4):824-8.
2009: Stephen P Hawser; Samuel K Bouchillon; Daryl J Hoban; Meredith Hackel; Jack L Johnson; Robert E Badal
Klebsiellapneumoniae isolates possessing KPC beta-lactamase in Israel, Puerto Rico, Colombia and Greece.
International journal of antimicrobial agents 2009;34(4):384-5.
2009: Stephen P Hawser; Samuel K Bouchillon; Daryl J Hoban; Robert E Badal; Po-Ren Hsueh; David L Paterson
Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007.
Antimicrobial agents and chemotherapy 2009;53(8):3280-4.
2009: James A Karlowsky; Nachum Kaplan; Barry Hafkin; Daryl J Hoban; George G Zhanel
AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity.
Antimicrobial agents and chemotherapy 2009;53(8):3544-8.
2009: George G Zhanel; Dylan Voth; Kim Nichol; James A Karlowsky; Ayman Noreddin; Daryl J Hoban
Pharmacodynamic activity of ceftobiprole compared with vancomycin versus methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant Staphylococcus aureus (VRSA) using an in vitro model.
The Journal of antimicrobial chemotherapy 2009;64(2):364-9.
2009: Heather J Adam; Daryl J Hoban; Alfred S Gin; George G Zhanel
Association between fluoroquinolone usage and a dramatic rise in ciprofloxacin-resistant Streptococcus pneumoniae in Canada, 1997-2006.
International journal of antimicrobial agents 2009;34(1):82-5.
2009: Patricia J Baudry; Kim Nichol; Melanie R DeCorby; Philippe R S Lagacé-Wiens; Erin Olivier; Dave Boyd; Michael Mulvey; Daryl J Hoban; George G Zhanel
Mechanisms of resistance and mobility among multidrug-resistant CTX-M-producing Escherichia coli from Canadian intensive care units: the 1st report of QepA in North America.
Diagnostic microbiology and infectious disease 2009;63(3):319-26.
2009: George G Zhanel; Grace Sniezek; Frank Schweizer; Sheryl A Zelenitsky; Philippe R S Lagacé-Wiens; Ethan Rubinstein; Alfred Gin; Daryl J Hoban; James A Karlowsky
Ceftaroline: a novel broad-spectrum cephalosporin with activity against meticillin-resistant Staphylococcus aureus.
Drugs 2009;69(7):809-31.
2008: George G Zhanel; Melanie R DeCorby; Kimberly A Nichol; Aleksandra Wierzbowski; Patricia J Baudry; James A Karlowsky; Philippe R S Lagacé-Wiens; Andrew Walkty; Michael Mulvey; Daryl J Hoban
Antimicrobial susceptibility of 3931 organisms isolated from intensive care units in Canada: Canadian National Intensive Care Unit Study, 2005/2006.
Diagnostic microbiology and infectious disease 2008;62(1):67-80.
2008: Philippe R S Lagacé-Wiens; George G Zhanel; Patricia J Baudry; Melanie R DeCorby; Daryl J Hoban; James A Karlowsky
Differences in antimicrobial susceptibility in Escherichia coli from Canadian intensive care units based on regional and demographic variables.
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada 2008;19(4):282-6.
2008: Andrew Walkty; Melanie Decorby; Kim Nichol; James A Karlowsky; Daryl J Hoban; George G Zhanel
In vitro activity of ceftobiprole against clinical isolates of Pseudomonas aeruginosa obtained from Canadian intensive care unit (ICU) patients as part of the CAN-ICU Study.
The Journal of antimicrobial chemotherapy 2008;62(1):206-8.
2008: Andrew Walkty; Melanie Decorby; Kim Nichol; Michael Mulvey; Daryl J Hoban; George Zhanel
Antimicrobial susceptibility of Pseudomonas aeruginosa isolates obtained from patients in Canadian intensive care units as part of the Canadian National Intensive Care Unit study.
Diagnostic microbiology and infectious disease 2008;61(2):217-21.
2008: George G Zhanel; Melanie R DeCorby; Kimberly A Nichol; Patricia J Baudry; James A Karlowsky; Philippe Rs Lagace-Wiens; Melissa McCracken; Michael Mulvey; Daryl J Hoban
Characterization of methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci and extended-spectrum beta-lactamase-producing Escherichia coli in intensive care units in Canada: Results of the Canadian National Intensive Care Unit (CAN-ICU) study (2005-2006).
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada 2008;19(3):243-9.
2008: Patricia J Baudry; Kim Nichol; Melanie R DeCorby; Laura Mataseje; Michael Mulvey; Daryl J Hoban; George G Zhanel
Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units.
Antimicrobial agents and chemotherapy 2008;52(5):1846-9.
2008: George G Zhanel; Melanie R DeCorby; Nancy Laing; Barb Weshnoweski; Ravi Vashisht; Franil Tailor; Kimberly A Nichol; Aleksandra Wierzbowski; Patricia J Baudry; James A Karlowsky; Philippe R S Lagacé-Wiens; Andrew Walkty; Melissa McCracken; Michael Mulvey; Jack Johnson; Daryl J Hoban
Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006.
Antimicrobial agents and chemotherapy 2008;52(4):1430-7.
2008: George G Zhanel; Patricia Baudry; Vibhu Vashisht; Nancy Laing; Ayman Noreddin; Daryl J Hoban
Pharmacodynamic activity of ertapenem versus multidrug-resistant genotypically characterized extended-spectrum beta-lactamase-producing Escherichia coli using an in vitro model.
The Journal of antimicrobial chemotherapy 2008;61(3):643-6.
2008: Kimberly A Nichol; Heather J Adam; James A Karlowsky; George G Zhanel; Daryl J Hoban
Increasing genetic relatedness of ciprofloxacin-resistant Streptococcus pneumoniae isolated in Canada from 1997 to 2005.
Antimicrobial agents and chemotherapy 2008;52(3):1190-4.
2008: George G Zhanel; Shannon Trapp; Alfred Gin; Melanie R DeCorby; Philippe R S Lagacé-Wiens; Ethan Rubinstein; Daryl J Hoban; James A Karlowsky
Dalbavancin and telavancin: novel lipoglycopeptides for the treatment of Gram-positive infections.
Expert review of anti-infective therapy 2008;6(1):67-81.
2008: George G Zhanel; Ashley Lam; Frank Schweizer; Kristjan Thomson; Andrew Walkty; Ethan Rubinstein; Alfred S Gin; Daryl J Hoban; Ayman M Noreddin; James A Karlowsky
Ceftobiprole: a review of a broad-spectrum and anti-MRSA cephalosporin.
American journal of clinical dermatology 2008;9(4):245-54.
2007: Ayman Noreddin; Angela A Reese; Melissa Ostroski; Daryl J Hoban; George G Zhanel
Comparative pharmacodynamics of garenoxacin, gemifloxacin, and moxifloxacin in community-acquired pneumonia caused by Streptococcus pneumoniae: a Monte Carlo simulation analysis.
Clinical therapeutics 2007;29(12):2685-9.
2007: Aleksandra Wierzbowski; Kim Nichol; Nancy Laing; Tamiko Hisanaga; A Nikulin; James A Karlowsky; Daryl J Hoban; George G Zhanel
Macrolide resistance mechanisms among Streptococcus pneumoniae isolated over 6 years of Canadian Respiratory Organism Susceptibility Study (CROSS) (1998 2004).
The Journal of antimicrobial chemotherapy 2007;60(4):733-40.
2007: James A Karlowsky; Samantha Kasloff; Kimberly A Nichol; Daryl J Hoban; George G Zhanel
Genetic relatedness of multidrug-resistant Escherichia coli cultured from geographically diverse outpatient, midstream urine specimens.
Diagnostic microbiology and infectious disease 2007;58(3):283-7.
2007: Daryl J Hoban; Samuel K Bouchillon; Michael J Dowzicky
Antimicrobial susceptibility of extended-spectrum beta-lactamase producers and multidrug-resistant Acinetobacter baumannii throughout the United States and comparative in vitro activity of tigecycline, a new glycylcycline antimicrobial.
Diagnostic microbiology and infectious disease 2007;57(4):423-8.
2007: Kristen N Schurek; Ryan Wiebe; James A Karlowsky; Ethan Rubinstein; Daryl J Hoban; George G Zhanel
Faropenem: review of a new oral penem.
Expert review of anti-infective therapy 2007;5(2):185-98.
2007: James A Karlowsky; Nancy M Laing; Trish Baudry; Nachum Kaplan; David Vaughan; Daryl J Hoban; George G Zhanel
In vitro activity of API-1252, a novel FabI inhibitor, against clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis.
Antimicrobial agents and chemotherapy 2007;51(4):1580-1.
2007: George G Zhanel; Ryan Wiebe; Leanne Dilay; Kristjan Thomson; Ethan Rubinstein; Daryl J Hoban; Ayman Noreddin; James A Karlowsky
Comparative review of the carbapenems.
Drugs 2007;67(7):1027-52.
2007: Heather J Adam; Kristen N Schurek; Kimberly A Nichol; Chris J Hoban; Trish J Baudry; Nancy M Laing; Daryl J Hoban; George G Zhanel
Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005.
Antimicrobial agents and chemotherapy 2007;51(1):198-207.
2007: George G Zhanel; Sheldon Derkatch; Nancy Laing; Ayman Noreddin; Daryl J Hoban
Pharmacodynamic activity of ertapenem versus penicillin-susceptible and penicillin-non-susceptible Streptococcus pneumoniae using an in vitro model.
The Journal of antimicrobial chemotherapy 2007;59(1):144-7.
2006: Daryl J Hoban; George G Zhanel
Clinical implications of macrolide resistance in community-acquired respiratory tract infections.
Expert review of anti-infective therapy 2006;4(6):973-80.
2006: George G Zhanel; Xi Wang; Kim Nichol; Anatoly Nikulin; Aleksandra Wierzbowski; Michael Mulvey; Daryl J Hoban
Molecular characterisation of Canadian paediatric multidrug-resistant Streptococcus pneumoniae from 1998-2004.
International journal of antimicrobial agents 2006;28(5):465-71.
2006: Kristen N Schurek; Heather J Adam; Daryl J Hoban; George G Zhanel
Call for the international adoption of microbiological breakpoints for fluoroquinolones and Streptococcus pneumoniae.
International journal of antimicrobial agents 2006;28(3):266-9.
2006: George G Zhanel; Joanne James; Sheldon Derkatch; Nancy Laing; Ayman Noreddin; Daryl J Hoban
Pharmacodynamic activity of garenoxacin against ciprofloxacin-resistant Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2006;58(1):112-6.
2006: Heather J Adam; Kristen N Schurek; Melanie R DeCorby; Barbara Weshnoweski; Ravinder Vashisht; Kathy Karlowsky; Daryl J Hoban; George G Zhanel
Comparative in vitro activity of PGE 9262932 and fluoroquinolones against Canadian clinical Streptococcus pneumoniae isolates, including molecularly characterized ciprofloxacin-resistant isolates.
The Journal of antimicrobial chemotherapy 2006;58(1):202-4.
2006: James A Karlowsky; Daryl J Hoban; Melanie R DeCorby; Nancy M Laing; George G Zhanel
Fluoroquinolone-resistant urinary isolates of Escherichia coli from outpatients are frequently multidrug resistant: results from the North American Urinary Tract Infection Collaborative Alliance-Quinolone Resistance study.
Antimicrobial agents and chemotherapy 2006;50(6):2251-4.
2006: George G Zhanel; Tamiko Hisanaga; Nancy M Laing; Melanie R DeCorby; Kimberly A Nichol; Barb Weshnoweski; Jack Johnson; Ayman Noreddin; Donald E Low; James A Karlowsky; Daryl J Hoban
Antibiotic resistance in Escherichia coli outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA).
International journal of antimicrobial agents 2006;27(6):468-75.
2006: Kimberly A Nichol; Michelle Sill; Nancy M Laing; Jack L Johnson; Daryl J Hoban; George G Zhanel
Molecular epidemiology of urinary tract isolates of vancomycin-resistant Enterococcus faecium from North America.
International journal of antimicrobial agents 2006;27(5):392-6.
2006: George G Zhanel; Tamiko Hisanaga; Aleksandra Wierzbowski; Daryl J Hoban
Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia.
Therapeutics and clinical risk management 2006;2(1):59-75.
2006: Aleksandra Wierzbowski; Daryl J Hoban; Tamiko Hisanaga; Melanie R DeCorby; George G Zhanel
The use of macrolides in treatment of upper respiratory tract infections.
Current allergy and asthma reports 2006;6(2):171-81.
2006: George G Zhanel; James A Karlowsky; Ethan Rubinstein; Daryl J Hoban
Tigecycline: a novel glycylcycline antibiotic.
Expert review of anti-infective therapy 2006;4(1):9-25.
2006: James A Karlowsky; Daryl J Hoban; George G Zhanel; Beth P Goldstein
In vitro interactions of anidulafungin with azole antifungals, amphotericin B and 5-fluorocytosine against Candida species.
International journal of antimicrobial agents 2006;27(2):174-7.
2006: George G Zhanel; Heather Adam; Sonya Fontaine; Alfred S Gin; Matt Mayer; Ayman Noreddin; Ethan Rubinstein; Kristen N Schurek; Daryl J Hoban
A Review of New Fluoroquinolones : Focus on their Use in Respiratory Tract Infections.
Treatments in respiratory medicine 2006;5(6):437-65.
2005: Aleksandra Wierzbowski; Dave Boyd; Michael Mulvey; Daryl J Hoban; George G Zhanel
Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides.
Antimicrobial agents and chemotherapy 2005;49(11):4635-40.
2005: George G Zhanel; Tamiko Hisanaga; Nancy M Laing; Melanie R DeCorby; Kimberly A Nichol; Lorraine P Palatnik; Jack Johnson; Ayman Noreddin; Godfrey K M Harding; Lindsay E Nicolle; Daryl J Hoban
Antibiotic resistance in outpatient urinary isolates: final results from the North American Urinary Tract Infection Collaborative Alliance (NAUTICA).
International journal of antimicrobial agents 2005;26(5):380-8.
2005: Kristen N Schurek; Heather J Adam; Christine G Siemens; Chris J Hoban; Daryl J Hoban; George G Zhanel
Are fluoroquinolone-susceptible isolates of Streptococcus pneumoniae really susceptible? A comparison of resistance mechanisms in Canadian isolates from 1997 and 2003.
The Journal of antimicrobial chemotherapy 2005;56(4):769-72.
2005: Tamiko Hisanaga; Daryl J Hoban; George G Zhanel
Mechanisms of resistance to telithromycin in Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2005;56(3):447-50.
2005: Ayman Noreddin; Daryl J Hoban; George G Zhanel
Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniae.
International journal of antimicrobial agents 2005;26(2):120-5.
2005: Daryl J Hoban; Samuel K Bouchillon; Brian M Johnson; Jack L Johnson; Michael J Dowzicky
In vitro activity of tigecycline against 6792 Gram-negative and Gram-positive clinical isolates from the global Tigecycline Evaluation and Surveillance Trial (TEST Program, 2004).
Diagnostic microbiology and infectious disease 2005;52(3):215-27.
2005: Samuel K Bouchillon; Daryl J Hoban; Brian M Johnson; Jack L Johnson; Andre Hsiung; Michael J Dowzicky
In vitro activity of tigecycline against 3989 Gram-negative and Gram-positive clinical isolates from the United States Tigecycline Evaluation and Surveillance Trial (TEST Program; 2004).
Diagnostic microbiology and infectious disease 2005;52(3):173-9.
2005: Samuel K Bouchillon; Jack L Johnson; Daryl J Hoban; Tim M Stevens; Brian M Johnson
Impact of carbon dioxide on the susceptibility of key respiratory tract pathogens to telithromycin and azithromycin.
The Journal of antimicrobial chemotherapy 2005;56(1):224-7.
2005: George G Zhanel; Christel Johanson; Nancy Laing; Tamiko Hisanaga; Aleksandra Wierzbowski; Daryl J Hoban
Pharmacodynamic activity of telithromycin at simulated clinically achievable free-drug concentrations in serum and epithelial lining fluid against efflux (mefE)-producing macrolide-resistant Streptococcus pneumoniae for which telithromycin MICs vary.
Antimicrobial agents and chemotherapy 2005;49(5):1943-8.
2005: Samuel K Bouchillon; Daryl J Hoban; Brian M Johnson; Tim M Stevens; Michael J Dowzicky; David H Wu; Patricia A Bradford
In vitro evaluation of tigecycline and comparative agents in 3049 clinical isolates: 2001 to 2002.
Diagnostic microbiology and infectious disease 2005;51(4):291-5.
2005: Aleksandra Wierzbowski; Dean Swedlo; Dave Boyd; Michael Mulvey; Kimberly A Nichol; Daryl J Hoban; George G Zhanel
Molecular epidemiology and prevalence of macrolide efflux genes mef(A) and mef(E) in Streptococcus pneumoniae obtained in Canada from 1997 to 2002.
Antimicrobial agents and chemotherapy 2005;49(3):1257-61.
2005: George G Zhanel; Christel Johanson; John M Embil; Ayman Noreddin; Alfred Gin; Lavern M Vercaigne; Daryl J Hoban
Ertapenem: review of a new carbapenem.
Expert review of anti-infective therapy 2005;3(1):23-39.
2005: Heather J Smith-Adam; Kimberly A Nichol; Daryl J Hoban; George G Zhanel
Stability of fluoroquinolone resistance in Streptococcus pneumoniae clinical isolates and laboratory-derived mutants.
Antimicrobial agents and chemotherapy 2005;49(2):846-8.
2004: George G Zhanel; Daryl J Hoban; Kristen N Schurek; James A Karlowsky
Role of efflux mechanisms on fluoroquinolone resistance in Streptococcus pneumoniae and Pseudomonas aeruginosa.
International journal of antimicrobial agents 2004;24(6):529-35.
2004: George G Zhanel; Christel Johanson; Tamiko Hisanaga; Chris Mendoza; Nancy Laing; Ayman Noreddin; Aleksandra Wierzbowski; Daryl J Hoban
Pharmacodynamic activity of telithromycin against macrolide-susceptible and macrolide-resistant Streptococcus pneumoniae simulating clinically achievable free serum and epithelial lining fluid concentrations.
The Journal of antimicrobial chemotherapy 2004;54(6):1072-7.
2004: Ayman Noreddin; Theodore K Marras; Kevin Sanders; Charles K N Chan; Daryl J Hoban; George G Zhanel
Pharmacodynamic target attainment analysis against Streptococcus pneumoniae using levofloxacin 500 mg, 750 mg and 1000 mg once daily in plasma (P) and epithelial lining fluid (ELF) of hospitalized patients with community acquired pneumonia (CAP).
International journal of antimicrobial agents 2004;24(5):479-84.
2004: Heather J Smith; Michael Walters; Tamiko Hisanaga; George G Zhanel; Daryl J Hoban
Mutant prevention concentrations for single-step fluoroquinolone-resistant mutants of wild-type, efflux-positive, or ParC or GyrA mutation-containing Streptococcus pneumoniae isolates.
Antimicrobial agents and chemotherapy 2004;48(10):3954-8.
2004: H J Smith; Ayman Noreddin; C G Siemens; Kristen N Schurek; J Greisman; Chris J Hoban; Daryl J Hoban; George G Zhanel
Designing fluoroquinolone breakpoints for Streptococcus pneumoniae by using genetics instead of pharmacokinetics-pharmacodynamics.
Antimicrobial agents and chemotherapy 2004;48(9):3630-5.
2004: Samuel K Bouchillon; Brian M Johnson; Daryl J Hoban; Jack L Johnson; Michael J Dowzicky; D H Wu; Melissa A Visalli; Patricia A Bradford
Determining incidence of extended spectrum beta-lactamase producing Enterobacteriaceae, vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus in 38 centres from 17 countries: the PEARLS study 2001-2002.
International journal of antimicrobial agents 2004;24(2):119-24.
2004: Marek Rzeszutek; Aleksandra Wierzbowski; Daryl J Hoban; John M Conly; William R Bishai; George G Zhanel
A review of clinical failures associated with macrolide-resistant Streptococcus pneumoniae.
International journal of antimicrobial agents 2004;24(2):95-104.
2004: Samuel K Bouchillon; Daryl J Hoban; Jack L Johnson; Brian M Johnson; DL Butler; KA Saunders; Linda A Miller; James Poupard
In vitro activity of gemifloxacin and contemporary oral antimicrobial agents against 27247 Gram-positive and Gram-negative aerobic isolates: a global surveillance study.
International journal of antimicrobial agents 2004;23(2):181-96.
2004: George G Zhanel; Kristen Homenuik; Kim Nichol; Ayman Noreddin; Lavern M Vercaigne; John M Embil; Alfred Gin; James A Karlowsky; Daryl J Hoban
The glycylcyclines: a comparative review with the tetracyclines.
Drugs 2004;64(1):63-88.
2003: George G Zhanel; Tamiko Hisanaga; Kim Nichol; Aleksandra Wierzbowski; Daryl J Hoban
Ketolides: an emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae.
Expert opinion on emerging drugs 2003;8(2):297-321.
2003: George G Zhanel; Nancy M Laing; Kimberly A Nichol; Lorraine Palatnick; Ayman Noreddin; Tamiko Hisanaga; Jack L Johnson; Daryl J Hoban
Antibiotic activity against urinary tract infection (UTI) isolates of vancomycin-resistant enterococci (VRE): results from the 2002 North American Vancomycin Resistant Enterococci Susceptibility Study (NAVRESS).
The Journal of antimicrobial chemotherapy 2003;52(3):382-8.
2003: George G Zhanel; Melanie R DeCorby; Ayman Noreddin; Chris Mendoza; Andrew Cumming; Kim Nichol; Aleksandra Wierzbowski; Daryl J Hoban
Pharmacodynamic activity of azithromycin against macrolide-susceptible and -resistant Streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations.
The Journal of antimicrobial chemotherapy 2003;52(1):83-8.
2003: George G Zhanel; Lorraine Palatnick; Kimberly A Nichol; Donald E Low; Daryl J Hoban
Antimicrobial resistance in Haemophilus influenzae and Moraxella catarrhalis respiratory tract isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002.
Antimicrobial agents and chemotherapy 2003;47(6):1875-81.
2003: George G Zhanel; Lorraine Palatnick; Kimberly A Nichol; Tracy Bellyou; Donald E Low; Daryl J Hoban
Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002.
Antimicrobial agents and chemotherapy 2003;47(6):1867-74.
2003: Heather J Smith; Kimberly A Nichol; Daryl J Hoban; George G Zhanel
Stretching the mutant prevention concentration (MPC) beyond its limits.
The Journal of antimicrobial chemotherapy 2003;51(6):1323-5.
2003: Daryl J Hoban; Samuel K Bouchillon; Jack L Johnson; GG Zhanel; DL Butler; KA Saunders; Linda A Miller; James Poupard
Comparative in vitro potency of amoxycillin-clavulanic acid and four oral agents against recent North American clinical isolates from a global surveillance study.
International journal of antimicrobial agents 2003;21(5):425-33.
2003: Daryl J Hoban; Douglas J Biedenbach; Alan H Mutnick; Ronald Jones
Pathogen of occurrence and susceptibility patterns associated with pneumonia in hospitalized patients in North America: results of the SENTRY Antimicrobial Surveillance Study (2000).
Diagnostic microbiology and infectious disease 2003;45(4):279-85.
2003: Daryl J Hoban; Samuel K Bouchillon; Jack L Johnson; GG Zhanel; DL Butler; KA Saunders; Linda A Miller; James Poupard
Comparative in vitro surveillance of amoxicillin-clavulanic acid and four oral comparators against 21232 clinical isolates from europe.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2003;22(4):261-7.
2003: Kimberly A Nichol; George G Zhanel; Daryl J Hoban
Molecular epidemiology of penicillin-resistant and ciprofloxacin-resistant Streptococcus pneumoniae in Canada.
Antimicrobial agents and chemotherapy 2003;47(2):804-8.
2003: Daryl J Hoban
Antibiotics and collateral damage.
Clinical cornerstone 2003;Suppl 3():S12-20.
2003: George G Zhanel; Andrew Walkty; Kim Nichol; Heather Smith; Ayman Noreddin; Daryl J Hoban
Molecular characterization of fluoroquinolone resistant Streptococcus pneumoniae clinical isolates obtained from across Canada.
Diagnostic microbiology and infectious disease 2003;45(1):63-7.
2002: Ayman Noreddin; Danielle Roberts; Kim Nichol; Aleksandra Wierzbowski; Daryl J Hoban; George G Zhanel
Pharmacodynamic modeling of clarithromycin against macrolide-resistant [PCR-positive mef(A) or erm(B)] Streptococcus pneumoniae simulating clinically achievable serum and epithelial lining fluid free-drug concentrations.
Antimicrobial agents and chemotherapy 2002;46(12):4029-34.
2002: Kimberly A Nichol; George G Zhanel; Daryl J Hoban
Penicillin-binding protein 1A, 2B, and 2X alterations in Canadian isolates of penicillin-resistant Streptococcus pneumoniae.
Antimicrobial agents and chemotherapy 2002;46(10):3261-4.
2002: George G Zhanel; Daryl J Hoban; Charles K Chan
Resistance to levofloxacin and failure of treatment of pneumococcal pneumonia.
The New England journal of medicine 2002;347(1):65-7; author reply 65-7.
2002: Daryl J Hoban
Prevalence and characterization of macrolide resistance in clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes from North America.
Journal of chemotherapy (Florence, Italy) 2002;14 Suppl 3():25-30.
2002: Heather J Smith; Kimberly A Nichol; Daryl J Hoban; George G Zhanel
Dual activity of fluoroquinolones against Streptococcus pneumoniae: the facts behind the claims.
The Journal of antimicrobial chemotherapy 2002;49(6):893-5.
2002: George G Zhanel; Danielle Roberts; Andrew Waltky; Nancy Laing; Kim Nichol; Heather Smith; Ayman Noreddin; Tracy Bellyou; Daryl J Hoban
Pharmacodynamic activity of fluoroquinolones against ciprofloxacin-resistant Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2002;49(5):807-12.
2002: Andrea S Gershon; Joyce C S De Azavedo; Allison McGeer; Krystyna I Ostrowska; Deirdre Church; Daryl J Hoban; Godfrey K M Harding; Karl Weiss; Lewis Abbott; Fiona Smaill; Marie Gourdeau; Gilles Murray; Donald E Low
Activities of new fluoroquinolones, ketolides, and other antimicrobials against blood culture isolates of viridans group streptococci from across Canada, 2000.
Antimicrobial agents and chemotherapy 2002;46(5):1553-6.
2002: George G Zhanel; Daryl J Hoban
Ketolides in the treatment of respiratory infections.
Expert opinion on pharmacotherapy 2002;3(3):277-97.
2002: George G Zhanel; Michael Walters; Ayman Noreddin; Lavern M Vercaigne; Aleksandra Wierzbowski; John M Embil; Alfred Gin; Stephen Douthwaite; Daryl J Hoban
The ketolides: a critical review.
Drugs 2002;62(12):1771-804.
2002: George G Zhanel; Kelly Ennis; Lavern M Vercaigne; Andrew Walkty; Alfred Gin; John M Embil; Heather Smith; Daryl J Hoban
A critical review of the fluoroquinolones: focus on respiratory infections.
Drugs 2002;62(1):13-59.
2001: MR Turnak; SI Bandak; Samuel K Bouchillon; BS Allen; Daryl J Hoban
Antimicrobial susceptibilities of clinical isolates of Haemophilus influenzae and Moraxella catarrhalis collected during 1999-2000 from 13 countries.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2001;7(12):671-7.
2001: Daryl J Hoban; Samuel K Bouchillon; Jack L Johnson; GG Zhanel; DL Butler; Linda A Miller; James Poupard
Comparative in vitro potency of gemifloxacin and fluoroquinolones against recent European clinical isolates from a global surveillance study.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2001;20(11):814-9.
2001: Tony Mazzulli; M Skulnick; G Small; W Marshall; Daryl J Hoban; G G Zhanel; S Finn; Donald E Low
Susceptibility of community Gram-negative urinary tract isolates to mecillinam and other oral agents.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 2001;12(5):289-92.
2001: Daryl J Hoban; Aleksandra Wierzbowski; Kim Nichol; George G Zhanel
Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides.
Antimicrobial agents and chemotherapy 2001;45(7):2147-50.
2001: George G Zhanel; D G Saunders; Daryl J Hoban; James A Karlowsky
Influence of human serum on antifungal pharmacodynamics with Candida albicans.
Antimicrobial agents and chemotherapy 2001;45(7):2018-22.
2001: Daryl J Hoban; G V Doern; A C Fluit; M Roussel-Delvallez; Ronald Jones
Worldwide prevalence of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the SENTRY Antimicrobial Surveillance Program, 1997-1999.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32 Suppl 2():S81-93.
2001: Daryl J Hoban; Samuel K Bouchillon; Jack L Johnson; GG Zhanel; DL Butler; Linda A Miller; James Poupard
Comparative in vitro activity of gemifloxacin, ciprofloxacin, levofloxacin and ofloxacin in a North American surveillance study.
Diagnostic microbiology and infectious disease 2001;40(1-2):51-7.
2001: George G Zhanel; M Walters; Nancy Laing; Daryl J Hoban
In vitro pharmacodynamic modelling simulating free serum concentrations of fluoroquinolones against multidrug-resistant Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2001;47(4):435-40.
2001: George G Zhanel; M Dueck; Daryl J Hoban; Lavern M Vercaigne; John M Embil; Alfred Gin; James A Karlowsky
Review of macrolides and ketolides: focus on respiratory tract infections.
Drugs 2001;61(4):443-98.
2001: SI Bandak; MR Turnak; BS Allen; LD Bolzon; DA Preston; Samuel K Bouchillon; Daryl J Hoban
Antibiotic susceptibilities among recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis from fifteen countries.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2001;20(1):55-60.
2001: George G Zhanel; Daryl J Hoban; James A Karlowsky
Nitrofurantoin is active against vancomycin-resistant enterococci.
Antimicrobial agents and chemotherapy 2001;45(1):324-6.
2000: Daryl J Hoban; Samuel K Bouchillon; J A Karlowsky; Jack L Johnson; DL Butler; Linda A Miller; James Poupard
A comparative In vitro surveillance study of gemifloxacin activities against 2,632 recent Streptococcus pneumoniae isolates from across Europe, North America, and South America. The Gemifloxacin Surveillance Study Research Group.
Antimicrobial agents and chemotherapy 2000;44(11):3008-11.
2000: James A Karlowsky; G Verma; George G Zhanel; Daryl J Hoban
Presence of ROB-1 beta-lactamase correlates with cefaclor resistance among recent isolates of Haemophilus influenzae.
The Journal of antimicrobial chemotherapy 2000;45(6):871-5.
2000: George G Zhanel; James A Karlowsky; Donald E Low; Daryl J Hoban
Antibiotic resistance in respiratory tract isolates of Haemophilus influenzae and Moraxella catarrhalis collected from across Canada in 1997-1998.
The Journal of antimicrobial chemotherapy 2000;45(5):655-62.
2000: George G Zhanel; James A Karlowsky; Godfrey K M Harding; Anita G Carrie; T Mazzulli; Donald E Low; Daryl J Hoban
A Canadian national surveillance study of urinary tract isolates from outpatients: comparison of the activities of trimethoprim-sulfamethoxazole, ampicillin, mecillinam, nitrofurantoin, and ciprofloxacin. The Canadian Urinary Isolate Study Group.
Antimicrobial agents and chemotherapy 2000;44(4):1089-92.
2000: Christine Turenne; E Witwicki; Daryl J Hoban; James A Karlowsky; Amin Kabani
Rapid identification of bacteria from positive blood cultures by fluorescence-based PCR-single-strand conformation polymorphism analysis of the 16S rRNA gene.
Journal of clinical microbiology 2000;38(2):513-20.
2000: George G Zhanel; Godfrey K M Harding; Stuart Rosser; Daryl J Hoban; James A Karlowsky; Michelle J Alfa; Amin Kabani; John M Embil; Alfred Gin; T Williams; Lindsay E Nicolle
Low prevalence of VRE gastrointestinal colonization of hospitalized patients in Manitoba tertiary care and community hospitals.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 2000;11(1):38-41.
1999: George G Zhanel; James A Karlowsky; Lorraine Palatnick; Lavern M Vercaigne; Donald E Low; Daryl J Hoban
Prevalence of antimicrobial resistance in respiratory tract isolates of Streptococcus pneumoniae: results of a Canadian national surveillance study. The Canadian Respiratory Infection Study Group.
Antimicrobial agents and chemotherapy 1999;43(10):2504-9.
1999: Daryl J Hoban; George G Zhanel; James A Karlowsky
In vitro activity of the novel ketolide HMR 3647 and comparative oral antibiotics against Canadian respiratory tract isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.
Diagnostic microbiology and infectious disease 1999;35(1):37-44.
1999: James A Karlowsky; George G Zhanel; Daryl J Hoban
Vancomycin-resistant enterococci (VRE) colonization of high-risk patients in tertiary care Canadian hospitals. Canadian VRE Surveillance Group.
Diagnostic microbiology and infectious disease 1999;35(1):1-7.
1999: Daryl J Hoban; George G Zhanel; James A Karlowsky
In vitro susceptibilities of Candida and Cryptococcus neoformans isolates from blood cultures of neutropenic patients.
Antimicrobial agents and chemotherapy 1999;43(6):1463-4.
1999: Christine Turenne; SE Sanche; Daryl J Hoban; James A Karlowsky; Amin Kabani
Rapid identification of fungi by using the ITS2 genetic region and an automated fluorescent capillary electrophoresis system.
Journal of clinical microbiology 1999;37(6):1846-51.
1999: George G Zhanel; John M Embil; Alfred Gin; James A Karlowsky; Lavern M Vercaigne; Andrew Walkty; Daryl J Hoban
The new fluoroquinolones: A critical review.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1999;10(3):207-38.
1999: Sheryl A Zelenitsky; B Booker; Nancy Laing; James A Karlowsky; Daryl J Hoban; George G Zhanel
Synergy of an investigational glycopeptide, LY333328, with once-daily gentamicin against vancomycin-resistant Enterococcus faecium in a multiple-dose, in vitro pharmacodynamic model.
Antimicrobial agents and chemotherapy 1999;43(3):592-7.
1999: Daryl J Hoban; James A Karlowsky; George G Zhanel
Evolving patterns of resistance to respiratory pathogens in Canada.
Canadian respiratory journal : journal of the Canadian Thoracic Society 1999;6 Suppl A():27A-30A.
1999: TV Balko; James A Karlowsky; Lorraine Palatnick; George G Zhanel; Daryl J Hoban
Characterization of the inoculum effect with Haemophilus influenzae and beta-lactams.
Diagnostic microbiology and infectious disease 1999;33(1):47-58.
1998: George G Zhanel; Alfred Gin; Amin Kabani; James A Karlowsky; Lindsay E Nicolle; Daryl J Hoban
Ciprofloxacin or imipenem use correlates with resistance in Pseudomonas aeruginosa.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1998;9(6):382-6.
1998: George G Zhanel; James A Karlowsky; B Schwartz; S B Jensen; Daryl J Hoban
Mecillinam activity compared to ampicillin, trimethoprim/sulfamethoxazole, ciprofloxacin and nitrofurantoin against urinary tract isolates of gram-negative bacilli.
Chemotherapy 1998;44(6):391-6.
1998: George G Zhanel; James A Karlowsky; Sheryl A Zelenitsky; MA Turik; Daryl J Hoban
Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents.
Antimicrobial agents and chemotherapy 1998;42(9):2446-8.
1998: George G Zhanel; Iain D C Kirkpatrick; Daryl J Hoban; Amin Kabani; James A Karlowsky
Influence of human serum on pharmacodynamic properties of an investigational glycopeptide, LY333328, and comparator agents against Staphylococcus aureus.
Antimicrobial agents and chemotherapy 1998;42(9):2427-30.
1998: Christine Y Turenne; Daryl J Hoban; James A Karlowsky; George G Zhanel; Amin Kabani
Screening of stool samples for identification of vancomycin-resistant Enterococcus isolates should include the methyl-alpha-D-glucopyranoside test to differentiate nonmotile Enterococcus gallinarum from E. faecium.
Journal of clinical microbiology 1998;36(8):2333-5.
1998: George G Zhanel; James A Karlowsky; Daryl J Hoban
In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species.
Diagnostic microbiology and infectious disease 1998;31(2):343-7.
1998: George G Zhanel; M H Saunders; Joyce N Wolfe; Daryl J Hoban; James A Karlowsky; Amin Kabani
Comparison of CO2 generation (BACTEC) and viable-count methods to determine the postantibiotic effect of antimycobacterial agents against Mycobacterium avium complex.
Antimicrobial agents and chemotherapy 1998;42(1):184-7.
1998: Sheryl A Zelenitsky; James A Karlowsky; Daryl J Hoban; Amin Kabani; George G Zhanel
Once versus thrice daily tobramycin alone and in combination with ceftazidime, ciprofloxacin and imipenem in an in vitro pharmacodynamic model.
Chemotherapy 1998;44(1):1-6.
1997: James A Karlowsky; G A Harding; Sheryl A Zelenitsky; Daryl J Hoban; Amin Kabani; TV Balko; MA Turik; George G Zhanel
In vitro kill curves of a new semisynthetic echinocandin, LY-303366, against fluconazole-sensitive and -resistant Candida species.
Antimicrobial agents and chemotherapy 1997;41(11):2576-8.
1997: James A Karlowsky; George G Zhanel; K A Klym; Daryl J Hoban; Amin Kabani
Candidemia in a Canadian tertiary care hospital from 1976 to 1996.
Diagnostic microbiology and infectious disease 1997;29(1):5-9.
1997: James A Karlowsky; Daryl J Hoban; Sheryl A Zelenitsky; George G Zhanel
Altered denA and anr gene expression in aminoglycoside adaptive resistance in Pseudomonas aeruginosa.
The Journal of antimicrobial chemotherapy 1997;40(3):371-6.
1997: James A Karlowsky; George G Zhanel; TV Balko; Sheryl A Zelenitsky; Amin Kabani; Daryl J Hoban
In vitro antifungal activity of BMS-181184 against systemic isolates of Candida, Cryptococcus, and Blastomyces species.
Diagnostic microbiology and infectious disease 1997;28(4):179-82.
1997: Sheryl A Zelenitsky; James A Karlowsky; George G Zhanel; Daryl J Hoban; T Nicas
Time-kill curves for a semisynthetic glycopeptide, LY333328, against vancomycin-susceptible and vancomycin-resistant Enterococcus faecium strains.
Antimicrobial agents and chemotherapy 1997;41(6):1407-8.
1997: George G Zhanel; James A Karlowsky; G A Harding; TV Balko; Sheryl A Zelenitsky; M Friesen; Amin Kabani; MA Turik; Daryl J Hoban
In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species.
Antimicrobial agents and chemotherapy 1997;41(4):863-5.
1996: James A Karlowsky; M H Saunders; G A Harding; Daryl J Hoban; George G Zhanel
In vitro characterization of aminoglycoside adaptive resistance in Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy 1996;40(6):1387-93.
1996: G R Drobot; James A Karlowsky; Daryl J Hoban; George G Zhanel
Antibiotic activity in microbiological media versus that in human urine: comparison of ampicillin, ciprofloxacin, and trimethoprim-sulfamethoxazole.
Antimicrobial agents and chemotherapy 1996;40(1):237-40.
1995: George G Zhanel; James A Karlowsky; M H Saunders; R J Davidson; Daryl J Hoban; R E Hancock; I McLean; Lindsay E Nicolle
Development of multiple-antibiotic-resistant (Mar) mutants of Pseudomonas aeruginosa after serial exposure to fluoroquinolones.
Antimicrobial agents and chemotherapy 1995;39(2):489-95.
1995: Daryl J Hoban; Ronald Jones
Canadian ofloxacin susceptibility study: a comparative study from 18 medical centers. Canadian Ofloxacin Study Group.
Chemotherapy 1995;41(1):34-8.
1994: R J Davidson; G R Drobot; James A Karlowsky; George G Zhanel; R Philips; Daryl J Hoban
The accumulation of fluoroquinolones in Staphylococcus aureus during the postantibiotic effect.
The Journal of antimicrobial chemotherapy 1994;34(3):363-70.
1994: S R Scriver; Daryl J Hoban; Allison McGeer; T C Moore; S L Walmsley; Donald E Low
Surveillance of susceptibility testing methodologies for Haemophilus influenzae in Canada, including evaluation of disk diffusion test.
Journal of clinical microbiology 1994;32(8):2013-5.
1994: S R Scriver; S L Walmsley; C L Kau; Daryl J Hoban; J Brunton; Allison McGeer; T C Moore; E Witwicki
Determination of antimicrobial susceptibilities of Canadian isolates of Haemophilus influenzae and characterization of their beta-lactamases. Canadian Haemophilus Study Group.
Antimicrobial agents and chemotherapy 1994;38(7):1678-80.
1994: Lindsay E Nicolle; Daryl J Hoban; M McIntyre; D Murray
Bacteremia in a long term care facility.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1994;5(3):130-2.
1994: James A Karlowsky; George G Zhanel; R J Davidson; Daryl J Hoban
Postantibiotic effect in Pseudomonas aeruginosa following single and multiple aminoglycoside exposures in vitro.
The Journal of antimicrobial chemotherapy 1994;33(5):937-47.
1994: James A Karlowsky; George G Zhanel; R J Davidson; Daryl J Hoban
Once-daily aminoglycoside dosing assessed by MIC reversion time with Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy 1994;38(5):1165-8.
1994: Nobuhisa Yamane; Ronald Jones; R Frei; Daryl J Hoban; A C C Pignatari; F Marco
Levofloxacin in vitro activity: results from an international comparative study with ofloxacin and ciprofloxacin.
Journal of chemotherapy (Florence, Italy) 1994;6(2):83-91.
1994: F Marco; Ronald Jones; Daryl J Hoban; A C C Pignatari; N Yamane; R Frei
In-vitro activity of OPC-17116 against more than 6000 consecutive clinical isolates: a multicentre international study.
The Journal of antimicrobial chemotherapy 1994;33(3):647-54.
1994: R Frei; Ronald Jones; A C C Pignatari; N Yamane; F Marco; Daryl J Hoban
Antimicrobial activity of FK-037, a new broad-spectrum cephalosporin. International in vitro comparison with cefepime and ceftazidime.
Diagnostic microbiology and infectious disease 1994;18(3):167-73.
1993: Daryl J Hoban; Ronald Jones; N Yamane; R Frei; A Trilla; A C C Pignatari
In vitro activity of three carbapenem antibiotics. Comparative studies with biapenem (L-627), imipenem, and meropenem against aerobic pathogens isolated worldwide.
Diagnostic microbiology and infectious disease 1993;17(4):299-305.
1993: Daryl J Hoban; Ronald Jones; L J Harrell; M Knudson; D Sewell
The North American component (the United States and Canada) of an International Comparative MIC trial monitoring ofloxacin resistance.
Diagnostic microbiology and infectious disease 1993;17(2):157-61.
1993: James A Karlowsky; George G Zhanel; R J Davidson; S R Zieroth; Daryl J Hoban
In vitro postantibiotic effects following multiple exposures of cefotaxime, ciprofloxacin, and gentamicin against Escherichia coli in pooled human cerebrospinal fluid and Mueller-Hinton broth.
Antimicrobial agents and chemotherapy 1993;37(5):1154-7.
1993: George G Zhanel; S O Kim; R J Davidson; Daryl J Hoban; Lindsay E Nicolle
Effect of subinhibitory concentrations of Ciprofloxacin and gentamicin on the adherence of Pseudomonas aeruginosa to Vero cells and voided uroepithelial cells.
Chemotherapy 1993;39(2):105-11.
1992: A H Chagla; S Ferro; J H Hii; Daryl J Hoban; R Poon; Andrew E Simor; E Witwicki; Donald E Low
Comparative antifungal activity of cilofungin (LY121019) against Candida species, including evaluation of susceptibility testing method.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1992;3(5):231-4.
1992: George G Zhanel; Daryl J Hoban; Godfrey K M Harding
Subinhibitory antimicrobial concentrations: A review of in vitro and in vivo data.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1992;3(4):193-201.
1992: Daryl J Hoban; B Weshnoweski; L Palatnick; C G Zhanel; R J Davidson
In-vitro activity of streptogramin RP 59500 against staphylococci, including bactericidal kinetic studies.
The Journal of antimicrobial chemotherapy 1992;30 Suppl A():59-65.
1992: George G Zhanel; James A Karlowsky; R J Davidson; Daryl J Hoban
Effect of pooled human cerebrospinal fluid on the postantibiotic effects of cefotaxime, ciprofloxacin, and gentamicin against Escherichia coli.
Antimicrobial agents and chemotherapy 1992;36(5):1136-9.
1992: George G Zhanel; J Crampton; S Kim; Lindsay E Nicolle; R J Davidson; Daryl J Hoban
Antimicrobial activity of subinhibitory concentrations of ciprofloxacin against Pseudomonas aeruginosa as determined by the killing curve method and the postantibiotic effect.
Chemotherapy 1992;38(6):388-94.
1991: R J Davidson; George G Zhanel; R Phillips; Daryl J Hoban
Human serum enhances the postantibiotic effect of fluoroquinolones against Staphylococcus aureus.
Antimicrobial agents and chemotherapy 1991;35(6):1261-3.
1991: George G Zhanel; Daryl J Hoban; G K Harding
The postantibiotic effect: a review of in vitro and in vivo data.
DICP : the annals of pharmacotherapy 1991;25(2):153-63.
1991: K Rodgers; Lindsay E Nicolle; Godfrey Harding; Daryl J Hoban; M McIntyre; D Murray
Pyuria in institutionalized elderly subjects.
The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1991;2(4):142-6.
1991: George G Zhanel; James A Karlowsky; Daryl J Hoban; R J Davidson
Antimicrobial activity of subinhibitory concentrations of aminoglycosides against Pseudomonas aeruginosa as determined by the killing-curve method and the postantibiotic effect.
Chemotherapy 1991;37(2):114-21.
1991: George G Zhanel; James A Karlowsky; R J Davidson; Daryl J Hoban
Influence of human urine on the in vitro activity and postantibiotic effect of ciprofloxacin against Escherichia coli.
Chemotherapy 1991;37(3):218-23.
1990: P G Jessamine; Daryl J Hoban; K R Forward
Positive Bactec resin cultures do not influence antimicrobial selection.
Diagnostic microbiology and infectious disease 1990;13(4):281-4.
1989: Daryl J Hoban; M Grabowski; J Koss; V Weselowski
Lomefloxacin, a new difluoroquinolone: in vitro activity against gram-positive and gram-negative bacteria.
Diagnostic microbiology and infectious disease 1989;12(3 Suppl):77S-82S.
1989: Daryl J Hoban; P DeGagne; E Witwicki
In vitro activity of lomefloxacin against Chlamydia trachomatis, Neisseria gonorrhoeae, Haemophilus ducreyi, Mycoplasma hominis, and Ureaplasma urealyticum.
Diagnostic microbiology and infectious disease 1989;12(3 Suppl):83S-86S.
1989: Daryl J Hoban
In-vitro activity of a new penem FCE 22101.
The Journal of antimicrobial chemotherapy 1989;23 Suppl C():53-7.
1989: Daryl J Hoban
Comparative in vitro activity of quinolones.
Clinical and investigative medicine. Médecine clinique et experimentale 1989;12(1):10-3.
1988: G J Sheehan; Godfrey K M Harding; D A Haase; M J Thomson; B Urias; J K Kennedy; Daryl J Hoban; Allan R Ronald
Double-blind, randomized comparison of 24 weeks of norfloxacin and 12 weeks of norfloxacin followed by 12 weeks of placebo in the therapy of complicated urinary tract infection.
Antimicrobial agents and chemotherapy 1988;32(8):1292-3.
1985: Daryl J Hoban; E Witwicki; G W Hammond
Bacterial antigen detection in cerebrospinal fluid of patients with meningitis.
Diagnostic microbiology and infectious disease 1985;3(5):373-9.