Denis Hochstrasser

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Licker Virginie; Kövari Enikö; Hochstrasser Denis F; Burkhard Pierre R
Proteomics in human Parkinson's disease research.
Farina Annarita; Dumonceau Jean-Marc; Frossard Jean-Louis; Hadengue Antoine; Hochstrasser Denis F; Lescuyer Pierre
Proteomic analysis of human bile from malignant biliary stenosis induced by pancreatic cancer.
Vaezzadeh Ali R; Hernandez Céline; Vadas Oscar; Deshusses Jacques J M; Lescuyer Pierre; Lisacek Frédérique; Hochstrasser Denis F
PICarver: a software tool and strategy for peptides isoelectric focusing.

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All Publications

2009: Licker Virginie; Kövari Enikö; Hochstrasser Denis F; Burkhard Pierre R
Proteomics in human Parkinson's disease research.
Journal of proteomics 2009;73(1):10-29.
2009: Farina Annarita; Dumonceau Jean-Marc; Frossard Jean-Louis; Hadengue Antoine; Hochstrasser Denis F; Lescuyer Pierre
Proteomic analysis of human bile from malignant biliary stenosis induced by pancreatic cancer.
Journal of proteome research 2009;8(1):159-69.
2008: Vaezzadeh Ali R; Hernandez Céline; Vadas Oscar; Deshusses Jacques J M; Lescuyer Pierre; Lisacek Frédérique; Hochstrasser Denis F
PICarver: a software tool and strategy for peptides isoelectric focusing.
Journal of proteome research 2008;7(10):4336-45.
2008: Fétaud Vanessa; Frossard Jean-Louis; Farina Annarita; Pastor Catherine M; Bühler Léo; Dumonceau Jean-Marc; Hadengue Antoine; Hochstrasser Denis F; Lescuyer Pierre
Proteomic profiling in an animal model of acute pancreatitis.
Proteomics 2008;8(17):3621-31.
2008: Vaezzadeh Ali R; Simicevic Jovan; Chauvet Alexis; François Patrice; Zimmermann-Ivol Catherine G; Lescuyer Pierre; Deshusses Jacques P M; Hochstrasser Denis F
Imaging mass spectrometry using peptide isoelectric focusing.
Rapid communications in mass spectrometry : RCM 2008;22(17):2667-76.
2008: Dayon Loïc; Hainard Alexandre; Licker Virginie; Turck Natacha; Kuhn Karsten; Hochstrasser Denis F; Burkhard Pierre R; Sanchez Jean-Charles
Relative quantification of proteins in human cerebrospinal fluids by MS/MS using 6-plex isobaric tags.
Analytical chemistry 2008;80(8):2921-31.
2007: Brunner Yannick; Couté Yohann; Iezzi Mariella; Foti Michelangelo; Fukuda Mitsonuri; Hochstrasser Denis F; Wollheim Claes B; Sanchez Jean-Charles
Proteomics analysis of insulin secretory granules.
Molecular & cellular proteomics : MCP 2007;6(6):1007-17.
2007: Schmid Gerhard M; Meda Paolo; Caille Dorothée; Wargent Ed; O'Dowd Jacqueline; Hochstrasser Denis F; Cawthorne Michael A; Sanchez Jean-Charles
Inhibition of insulin secretion by betagranin, an N-terminal chromogranin A fragment.
The Journal of biological chemistry 2007;282(17):12717-24.
2007: Allard Laure; Turck Natacha; Burkhard Pierre R; Walter Nadia; Rosell Anna; Gex-Fabry Marianne; Hochstrasser Denis F; Montaner Joan; Sanchez Jean-Charles
Ubiquitin fusion degradation protein 1 as a blood marker for the early diagnosis of ischemic stroke.
Biomarker insights 2007;2():155-64.
2006: Carrette Odile; Burkhard Pierre R; Hochstrasser Denis F; Sanchez Jean-Charles
Age-related proteome analysis of the mouse brain: a 2-DE study.
Proteomics 2006;6(18):4940-9.
2006: Carrette O; Burgess J A; Burkhard P R; Lang C; Côte M; Rodrigo N; Hochstrasser D F; Sanchez J-C
Changes of the cortex proteome and Apolipoprotein E in transgenic mouse models of Alzheimer's Disease.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;840(1):1-9.
2006: Burgess Jennifer A; Lescuyer Pierre; Hainard Alexandre; Burkhard Pierre R; Turck Natacha; Michel Philippe; Rossier Joël S; Reymond Frédéric; Hochstrasser Denis F; Sanchez Jean-Charles
Identification of brain cell death associated proteins in human post-mortem cerebrospinal fluid.
Journal of proteome research 2006;5(7):1674-81.
2006: Carrette Odile; Burkhard Pierre R; Sanchez Jean-Charles; Hochstrasser Denis F
State-of-the-art two-dimensional gel electrophoresis: a key tool of proteomics research.
Nature protocols 2006;1(2):812-23.
2006: Scherl Alexander; François Patrice; Charbonnier Yvan; Deshusses Jacques M; Koessler Thibaud; Huyghe Antoine; Bento Manuela; Stahl-Zeng Jianru; Fischer Adrien; Masselot Alexandre; Vaezzadeh Alireza; Gallé Francesca; Renzoni Adriana; Vaudaux Pierre; Lew Daniel; Zimmermann-Ivol Catherine G; Binz Pierre-Alain; Sanchez Jean-Charles; Hochstrasser Denis F; Schrenzel Jacques
Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers.
BMC genomics 2006;7():296.
2006: Luxembourg Stefan L; Vaezaddeh Ali R; Amstalden Erika R; Zimmermann-Ivol Catherine G; Hochstrasser Denis F; Heeren Ron M A
The molecular scanner in microscope mode.
Rapid communications in mass spectrometry : RCM 2006;20(22):3435-42.
2005: Lescuyer Pierre; Gandini Alberto; Burkhard Pierre R; Hochstrasser Denis F; Sanchez Jean-Charles
Prostaglandin D2 synthase and its post-translational modifications in neurological disorders.
Electrophoresis 2005;26(23):4563-70.
2005: Allard Laure; Burkhard Pierre R; Lescuyer Pierre; Burgess Jennifer A; Walter Nadia; Hochstrasser Denis F; Sanchez Jean-Charles
PARK7 and nucleoside diphosphate kinase A as plasma markers for the early diagnosis of stroke.
Clinical chemistry 2005;51(11):2043-51.
2005: Carrette Odile; Burkhard Pierre R; Hughes Severine; Hochstrasser Denis F; Sanchez Jean-Charles
Truncated cystatin C in cerebrospiral fluid: Technical [corrected] artefact or biological process?
Proteomics 2005;5(12):3060-5.
2005: Palagi Patricia M; Walther Daniel; Quadroni Manfredo; Catherinet Sébastien; Burgess Jennifer; Zimmermann-Ivol Catherine G; Sanchez Jean-Charles; Binz Pierre-Alain; Hochstrasser Denis F; Appel Ron D
MSight: an image analysis software for liquid chromatography-mass spectrometry.
Proteomics 2005;5(9):2381-4.
2005: Bilati Ugo; Pasquarello Carla; Corthals Garry L; Hochstrasser Denis F; Allémann Eric; Doelker Eric
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for quantitation and molecular stability assessment of insulin entrapped within PLGA nanoparticles.
Journal of pharmaceutical sciences 2005;94(3):688-94.
2005: Tremolada Lucia; Magni Fulvio; Valsecchi Cristina; Sarto Cecilia; Mocarelli Paolo; Perego Roberto; Cordani Nicoletta; Favini Paolo; Galli Kienle Marzia; Sanchez Jean-Charles; Hochstrasser Denis F; Corthals Garry L
Characterization of heat shock protein 27 phosphorylation sites in renal cell carcinoma.
Proteomics 2005;5(3):788-95.
2005: Scherl Alexander; François Patrice; Bento Manuela; Deshusses Jacques M; Charbonnier Yvan; Converset Véronique; Huyghe Antoine; Walter Nadia; Hoogland Christine; Appel Ron D; Sanchez Jean-Charles; Zimmermann-Ivol Catherine G; Corthals Garry L; Hochstrasser Denis F; Schrenzel Jacques
Correlation of proteomic and transcriptomic profiles of Staphylococcus aureus during the post-exponential phase of growth.
Journal of microbiological methods 2005;60(2):247-57.
2005: Lescuyer Pierre; Allard Laure; Hochstrasser Denis F; Sanchez Jean-Charles
Heart-fatty acid-binding protein as a marker for early detection of acute myocardial infarction and stroke.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 2005;9(1):1-7.
2005: Scherl Alexander; Zimmermann-Ivol Catherine G; Di Dio Joel; Vaezzadeh Ali R; Binz Pierre-Alain; Amez-Droz Michel; Cochard Roland; Sanchez Jean-Charles; Glückmann Matthias; Hochstrasser Denis F
Gold coating of non-conductive membranes before matrix-assisted laser desorption/ionization tandem mass spectrometric analysis prevents charging effect.
Rapid communications in mass spectrometry : RCM 2005;19(5):605-10.
2004: Hoogland Christine; Mostaguir Khaled; Sanchez Jean-Charles; Hochstrasser Denis F; Appel Ron D
SWISS-2DPAGE, ten years later.
Proteomics 2004;4(8):2352-6.
2004: Schmid Gerhard M; Converset Véronique; Walter Nadia; Sennitt Matthew V; Leung Kit-Yi; Byers Helen; Ward Malcolm; Hochstrasser Denis F; Cawthorne Michael A; Sanchez Jean-Charles
Effect of high-fat diet on the expression of proteins in muscle, adipose tissues, and liver of C57BL/6 mice.
Proteomics 2004;4(8):2270-82.
2004: Allard Laure; Lescuyer Pierre; Burgess Jennifer; Leung Kit-Yi; Ward Malcolm; Walter Nadia; Burkhard Pierre R; Corthals Garry; Hochstrasser Denis F; Sanchez Jean-Charles
ApoC-I and ApoC-III as potential plasmatic markers to distinguish between ischemic and hemorrhagic stroke.
Proteomics 2004;4(8):2242-51.
2004: Lescuyer Pierre; Allard Laure; Zimmermann-Ivol Catherine G; Burgess Jennifer A; Hughes-Frutiger Séverine; Burkhard Pierre R; Sanchez Jean-Charles; Hochstrasser Denis F
Identification of post-mortem cerebrospinal fluid proteins as potential biomarkers of ischemia and neurodegeneration.
Proteomics 2004;4(8):2234-41.
2004: Sanchez Jean-Charles; Guillaume Elisabeth; Lescuyer Pierre; Allard Laure; Carrette Odile; Scherl Alex; Burgess Jennifer; Corthals Garry L; Burkhard Pierre R; Hochstrasser Denis F
Cystatin C as a potential cerebrospinal fluid marker for the diagnosis of Creutzfeldt-Jakob disease.
Proteomics 2004;4(8):2229-33.
2004: Lescuyer Pierre; Hochstrasser Denis F; Sanchez Jean-Charles
Comprehensive proteome analysis by chromatographic protein prefractionation.
Electrophoresis 2004;25(7-8):1125-35.
2004: Scherl Alexander; Francois Patrice; Converset Véronique; Bento Manuela; Burgess Jennifer A; Sanchez Jean-Charles; Hochstrasser Denis F; Schrenzel Jacques; Corthals Garry L
Nonredundant mass spectrometry: a strategy to integrate mass spectrometry acquisition and analysis.
Proteomics 2004;4(4):917-27.
2004: Binz Pierre-Alain; Müller Markus; Hoogland Christine; Zimmermann Catherine; Pasquarello Carla; Corthals Garry; Sanchez Jean-Charles; Hochstrasser Denis F; Appel Ron D
The molecular scanner: concept and developments.
Current opinion in biotechnology 2004;15(1):17-23.
2004: Zimmermann-Ivol Catherine G; Burkhard Pierre R; Le Floch-Rohr Josette; Allard Laure; Hochstrasser Denis F; Sanchez Jean-Charles
Fatty acid binding protein as a serum marker for the early diagnosis of stroke: a pilot study.
Molecular & cellular proteomics : MCP 2004;3(1):66-72.
2004: Pasquarello Carla; Sanchez Jean-Charles; Hochstrasser Denis F; Corthals Garry L
N-t-butyliodoacetamide and iodoacetanilide: two new cysteine alkylating reagents for relative quantitation of proteins.
Rapid communications in mass spectrometry : RCM 2004;18(1):117-27.
2003: Binz Pierre-Alain; Hochstrasser Denis F; Appel Ron D
Mass spectrometry-based proteomics: current status and potential use in clinical chemistry.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(12):1540-51.
2003: Sanchez Jean-Charles; Converset Véronique; Nolan Anna; Schmid Gerhard; Wang Steven; Heller Manfred; Sennitt Matthew V; Hochstrasser Denis F; Cawthorne Michael A
Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice.
Proteomics 2003;3(8):1500-20.
2003: Guillaume Elisabeth; Zimmermann Catherine; Burkhard Pierre R; Hochstrasser Denis F; Sanchez Jean-Charles
A potential cerebrospinal fluid and plasmatic marker for the diagnosis of Creutzfeldt-Jakob disease.
Proteomics 2003;3(8):1495-9.
2003: Carrette Odile; Demalte Isabelle; Scherl Alexander; Yalkinoglu Oezkarn; Corthals Garry; Burkhard Pierre; Hochstrasser Denis F; Sanchez Jean-Charles
A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease.
Proteomics 2003;3(8):1486-94.
2003: Deshusses Jacques M P; Burgess Jennifer A; Scherl Alexander; Wenger Yvan; Walter Nadia; Converset Véronique; Paesano Salvo; Corthals Garry L; Hochstrasser Denis F; Sanchez Jean-Charles
Exploitation of specific properties of trifluoroethanol for extraction and separation of membrane proteins.
Proteomics 2003;3(8):1418-24.
2002: Müller Markus; Gras Robin; Binz Pierre-Alain; Hochstrasser Denis F; Appel Ron D
Molecular scanner experiment with human plasma: improving protein identification by using intensity distributions of matching peptide masses.
Proteomics 2002;2(10):1413-25.
2002: Gay Steven; Binz Pierre-Alain; Hochstrasser Denis F; Appel Ron D
Peptide mass fingerprinting peak intensity prediction: extracting knowledge from spectra.
Proteomics 2002;2(10):1374-91.
2002: Bienvenut Willy V; Déon Catherine; Sanchez Jean-Charles; Hochstrasser Denis F
Enhanced protein recovery after electrotransfer using square wave alternating voltage.
Analytical biochemistry 2002;307(2):297-303.
2002: Sanchez Jean-Charles; Converset Véronique; Nolan Anna; Schmid Gerhard; Wang Steven; Heller Manfred; Sennitt Matthew V; Hochstrasser Denis F; Cawthorne Michael A
Effect of rosiglitazone on the differential expression of diabetes-associated proteins in pancreatic islets of C57Bl/6 lep/lep mice.
Molecular & cellular proteomics : MCP 2002;1(7):509-16.
2002: Bienvenut Willy V; Déon Catherine; Pasquarello Carla; Campbell Jennifer M; Sanchez Jean-Charles; Vestal Marvin L; Hochstrasser Denis F
Matrix-assisted laser desorption/ionization-tandem mass spectrometry with high resolution and sensitivity for identification and characterization of proteins.
Proteomics 2002;2(7):868-76.
2002: Hochstrasser Denis F; Sanchez Jean-Charles; Appel Ron D
Proteomics and its trends facing nature's complexity.
Proteomics 2002;2(7):807-12.
2002: Tissot Jean-Daniel; Sanchez Jean-Charles; Vuadens Françoise; Scherl Alexander; Schifferli Jürg A; Hochstrasser Denis F; Schneider Philippe; Duchosal Michel A
IgM are associated to Sp alpha (CD5 antigen-like).
Electrophoresis 2002;23(7-8):1203-6.
2002: Müller Markus; Gras Robin; Appel Ron D; Bienvenut Willy V; Hochstrasser Denis F
Visualization and analysis of molecular scanner peptide mass spectra.
Journal of the American Society for Mass Spectrometry 2002;13(3):221-31.
2002: Vuadens Françoise; Gasparini Danielle; Déon Catherine; Sanchez Jean-Charles; Hochstrasser Denis F; Schneider Philippe; Tissot Jean-Daniel
Identification of specific proteins in different lymphocyte populations by proteomic tools.
Proteomics 2002;2(1):105-11.
2002: Geissbühler A; Lovis C; Spahni S; Appel R D; Ratib O; Boyer C; Hochstrasser D F; Baud R
A humanist's legacy in medical informatics: visions and accomplishments of Professor Jean-Raoul Scherrer.
Methods of information in medicine 2002;41(3):237-42.
2002: Bienvenut Willy V; Hoogland Christine; Greco Anna; Heller Manfred; Gasteiger Elisabeth; Appel Ron D; Diaz Jean-Jacques; Sanchez Jean-Charles; Hochstrasser Denis F
Hydrogen/deuterium exchange for higher specificity of protein identification by peptide mass fingerprinting.
Rapid communications in mass spectrometry : RCM 2002;16(6):616-26.
2001: Sarto C; Déon C; Doro G; Hochstrasser D F; Mocarelli P; Sanchez J C
Contribution of proteomics to the molecular analysis of renal cell carcinoma with an emphasis on manganese superoxide dismutase.
Proteomics 2001;1(10):1288-94.
2001: Guillaume E; Pineau C; Evrard B; Dupaix A; Moertz E; Sanchez J C; Hochstrasser D F; Jégou B
Cellular distribution of translationally controlled tumor protein in rat and human testes.
Proteomics 2001;1(7):880-9.
2001: Burkhard P R; Sanchez J C; Landis T; Hochstrasser D F
CSF detection of the 14-3-3 protein in unselected patients with dementia.
Neurology 2001;56(11):1528-33.
2001: Burkhard P R; Rodrigo N; May D; Sztajzel R; Sanchez J C; Hochstrasser D F; Schiffer E; Reverdin A; Lacroix J S;
Assessing cerebrospinal fluid rhinorrhea: a two-dimensional electrophoresis approach.
Electrophoresis 2001;22(9):1826-33.
2001: Tonella L; Hoogland C; Binz P A; Appel R D; Hochstrasser D F; Sanchez J C
New perspectives in the Escherichia coli proteome investigation.
Proteomics 2001;1(3):409-23.
2001: Sanchez J C; Chiappe D; Converset V; Hoogland C; Binz P A; Paesano S; Appel R D; Wang S; Sennitt M; Nolan A; Cawthorne M A; Hochstrasser D F
The mouse SWISS-2D PAGE database: a tool for proteomics study of diabetes and obesity.
Proteomics 2001;1(1):136-63.
2000: Jung E; Hoogland C; Chiappe D; Sanchez J C; Hochstrasser D F
The establishment of a human liver nuclei two-dimensional electrophoresis reference map.
Electrophoresis 2000;21(16):3483-7.
2000: Jung E; Heller M; Sanchez J C; Hochstrasser D F
Proteomics meets cell biology: the establishment of subcellular proteomes.
Electrophoresis 2000;21(16):3369-77.
2000: Kojima T; Andersen E; Sanchez J C; Wilkins M R; Hochstrasser D F; Pralong W F; Cimasoni G
Human gingival crevicular fluid contains MRP8 (S100A8) and MRP14 (S100A9), two calcium-binding proteins of the S100 family.
Journal of dental research 2000;79(2):740-7.
2000: Hoogland C; Sanchez J C; Tonella L; Binz P A; Bairoch A; Hochstrasser D F; Appel R D
The 1999 SWISS-2DPAGE database update.
Nucleic acids research 2000;28(1):286-8.
1999: Hoogland C; Sanchez J C; Walther D; Baujard V; Baujard O; Tonella L; Hochstrasser D F; Appel R D
Two-dimensional electrophoresis resources available from ExPASy.
Electrophoresis 1999;20(18):3568-71.
1999: Gras R; Müller M; Gasteiger E; Gay S; Binz P A; Bienvenut W; Hoogland C; Sanchez J C; Bairoch A; Hochstrasser D F; Appel R D
Improving protein identification from peptide mass fingerprinting through a parameterized multi-level scoring algorithm and an optimized peak detection.
Electrophoresis 1999;20(18):3535-50.
1999: Gay S; Binz P A; Hochstrasser D F; Appel R D
Modeling peptide mass fingerprinting data using the atomic composition of peptides.
Electrophoresis 1999;20(18):3527-34.
1999: Sarto C; Frutiger S; Cappellano F; Sanchez J C; Doro G; Catanzaro F; Hughes G J; Hochstrasser D F; Mocarelli P
Modified expression of plasma glutathione peroxidase and manganese superoxide dismutase in human renal cell carcinoma.
Electrophoresis 1999;20(17):3458-66.
1999: Binz P A; Müller M; Walther D; Bienvenut W V; Gras R; Hoogland C; Bouchet G; Gasteiger E; Fabbretti R; Gay S; Palagi P; Wilkins M R; Rouge V; Tonella L; Paesano S; Rossellat G; Karmime A; Bairoch A; Sanchez J C; Appel R D; Hochstrasser D F
A molecular scanner to automate proteomic research and to display proteome images.
Analytical chemistry 1999;71(21):4981-8.
1999: Bienvenut W V; Sanchez J C; Karmime A; Rouge V; Rose K; Binz P A; Hochstrasser D F
Toward a clinical molecular scanner for proteome research: parallel protein chemical processing before and during western blot.
Analytical chemistry 1999;71(21):4800-7.
1999: Wilkins M R; Gasteiger E; Gooley A A; Herbert B R; Molloy M P; Binz P A; Ou K; Sanchez J C; Bairoch A; Williams K L; Hochstrasser D F
High-throughput mass spectrometric discovery of protein post-translational modifications.
Journal of molecular biology 1999;289(3):645-57.
1999: Yan J X; Sanchez J C; Binz P A; Williams K L; Hochstrasser D F
Method for identification and quantitative analysis of protein lysine methylation using matrix-assisted laser desorption/ionization--time-of-flight mass spectrometry and amino acid analysis.
Electrophoresis 1999;20(4-5):749-54.
1999: Yan J X; Sanchez J C; Tonella L; Williams K L; Hochstrasser D F
Studies of quantitative analysis of protein expression in Saccharomyces cerevisiae.
Electrophoresis 1999;20(4-5):738-42.
1999: Yan J X; Sanchez J C; Rouge V; Williams K L; Hochstrasser D F
Modified immobilized pH gradient gel strip equilibration procedure in SWISS-2DPAGE protocols.
Electrophoresis 1999;20(4-5):723-6.
1999: Hoogland C; Sanchez J C; Tonella L; Bairoch A; Hochstrasser D F; Appel R D
The SWISS-2DPAGE database: what has changed during the last year.
Nucleic acids research 1999;27(1):289-91.
1999: Wilkins M R; Gasteiger E; Bairoch A; Sanchez J C; Williams K L; Appel R D; Hochstrasser D F
Protein identification and analysis tools in the ExPASy server.
Methods in molecular biology (Clifton, N.J.) 1999;112():531-52.
1999: Appel R D; Hoogland C; Bairoch A; Hochstrasser D F
Constructing a 2-D database for the World Wide Web.
Methods in molecular biology (Clifton, N.J.) 1999;112():411-6.
1999: Appel R D; Bairoch A; Hochstrasser D F
2-D databases on the World Wide Web.
Methods in molecular biology (Clifton, N.J.) 1999;112():383-91.
1999: Appel R D; Hochstrasser D F
Computer analysis of 2-D images.
Methods in molecular biology (Clifton, N.J.) 1999;112():363-81.
1999: Sanchez J C; Hochstrasser D F
High-resolution, IPG-based, mini two-dimensional gel electrophoresis.
Methods in molecular biology (Clifton, N.J.) 1999;112():227-33.
1999: Sanchez J C; Hochstrasser D F
Preparation and solubilization of body fluids for 2-D.
Methods in molecular biology (Clifton, N.J.) 1999;112():87-93.
1998: Wilkins M R; Gasteiger E; Wheeler C H; Lindskog I; Sanchez J C; Bairoch A; Appel R D; Dunn M J; Hochstrasser D F
Multiple parameter cross-species protein identification using MultiIdent--a world-wide web accessible tool.
Electrophoresis 1998;19(18):3199-206.
1998: Hochstrasser D F
Proteome in perspective.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1998;36(11):825-36.
1998: Tonella L; Walsh B J; Sanchez J C; Ou K; Wilkins M R; Tyler M; Frutiger S; Gooley A A; Pescaru I; Appel R D; Yan J X; Bairoch A; Hoogland C; Morch F S; Hughes G J; Williams K L; Hochstrasser D F
'98 Escherichia coli SWISS-2DPAGE database update.
Electrophoresis 1998;19(11):1960-71.
1998: Traini M; Gooley A A; Ou K; Wilkins M R; Tonella L; Sanchez J C; Hochstrasser D F; Williams K L
Towards an automated approach for protein identification in proteome projects.
Electrophoresis 1998;19(11):1941-9.
1998: Wilkins M R; Gasteiger E; Sanchez J C; Bairoch A; Hochstrasser D F
Two-dimensional gel electrophoresis for proteome projects: the effects of protein hydrophobicity and copy number.
Electrophoresis 1998;19(8-9):1501-5.
1998: Molloy M P; Herbert B R; Walsh B J; Tyler M I; Traini M; Sanchez J C; Hochstrasser D F; Williams K L; Gooley A A
Extraction of membrane proteins by differential solubilization for separation using two-dimensional gel electrophoresis.
Electrophoresis 1998;19(5):837-44.
1998: Wilkins M R; Gasteiger E; Tonella L; Ou K; Tyler M; Sanchez J C; Gooley A A; Walsh B J; Bairoch A; Appel R D; Williams K L; Hochstrasser D F
Protein identification with N and C-terminal sequence tags in proteome projects.
Journal of molecular biology 1998;278(3):599-608.
1998: Hoogland C; Sanchez J C; Tonella L; Bairoch A; Hochstrasser D F; Appel R D
Current status of the SWISS-2DPAGE database.
Nucleic acids research 1998;26(1):332-3.
1997: Bini L; Magi B; Marzocchi B; Arcuri F; Tripodi S; Cintorino M; Sanchez J C; Frutiger S; Hughes G; Pallini V; Hochstrasser D F; Tosi P
Protein expression profiles in human breast ductal carcinoma and histologically normal tissue.
Electrophoresis 1997;18(15):2832-41.
1997: Liberatori S; Bini L; De Felice C; Magi B; Marzocchi B; Raggiaschi R; Frutiger S; Sanchez J C; Wilkins M R; Hughes G; Hochstrasser D F; Bracci R; Pallini V
A two-dimensional protein map of human amniotic fluid at 17 weeks' gestation.
Electrophoresis 1997;18(15):2816-22.
1997: Hoogland C; Baujard V; Sanchez J C; Hochstrasser D F; Appel R D
Make2ddb: a simple package to set up a two-dimensional electrophoresis database for the World Wide Web.
Electrophoresis 1997;18(15):2755-8.
1997: Appel R D; Vargas J R; Palagi P M; Walther D; Hochstrasser D F
Melanie II--a third-generation software package for analysis of two-dimensional electrophoresis images: II. Algorithms.
Electrophoresis 1997;18(15):2735-48.
1997: Appel R D; Palagi P M; Walther D; Vargas J R; Sanchez J C; Ravier F; Pasquali C; Hochstrasser D F
Melanie II--a third-generation software package for analysis of two-dimensional electrophoresis images: I. Features and user interface.
Electrophoresis 1997;18(15):2724-34.
1997: Hochstrasser D F; Frutiger S; Wilkins M R; Hughes G; Sanchez J C
Elevation of apolipoprotein E in the CSF of cattle affected by BSE.
FEBS letters 1997;416(2):161-3.
1997: Gooley A A; Ou K; Russell J; Wilkins M R; Sanchez J C; Hochstrasser D F; Williams K L
A role for Edman degradation in proteome studies.
Electrophoresis 1997;18(7):1068-72.
1997: Sanchez J C; Wirth P; Jaccoud S; Appel R D; Sarto C; Wilkins M R; Hochstrasser D F
Simultaneous analysis of cyclin and oncogene expression using multiple monoclonal antibody immunoblots.
Electrophoresis 1997;18(3-4):638-41.
1997: Sarto C; Marocchi A; Sanchez J C; Giannone D; Frutiger S; Golaz O; Wilkins M R; Doro G; Cappellano F; Hughes G; Hochstrasser D F; Mocarelli P
Renal cell carcinoma and normal kidney protein expression.
Electrophoresis 1997;18(3-4):599-604.
1997: Cossio G; Sanchez J C; Wettstein R; Hochstrasser D F
Spermatocytes and round spermatids of rat testis: the difference between in vivo and in vitro protein patterns.
Electrophoresis 1997;18(3-4):548-52.
1997: Peitsch M C; Wilkins M R; Tonella L; Sanchez J C; Appel R D; Hochstrasser D F
Large-scale protein modelling and integration with the SWISS-PROT and SWISS-2DPAGE databases: the example of Escherichia coli.
Electrophoresis 1997;18(3-4):498-501.
1997: Yan J X; Tonella L; Sanchez J C; Wilkins M R; Packer N H; Gooley A A; Hochstrasser D F; Williams K L
The Dictyostelium discoideum proteome--the SWISS-2DPAGE database of the multicellular aggregate (slug).
Electrophoresis 1997;18(3-4):491-7.
1997: Wilkins M R; Lindskog I; Gasteiger E; Bairoch A; Sanchez J C; Hochstrasser D F; Appel R D
Detailed peptide characterization using PEPTIDEMASS--a World-Wide-Web-accessible tool.
Electrophoresis 1997;18(3-4):403-8.
1997: Sanchez J C; Rouge V; Pisteur M; Ravier F; Tonella L; Moosmayer M; Wilkins M R; Hochstrasser D F
Improved and simplified in-gel sample application using reswelling of dry immobilized pH gradients.
Electrophoresis 1997;18(3-4):324-7.
1996: Wilkins M R; Gasteiger E; Sanchez J C; Appel R D; Hochstrasser D F
Protein identification with sequence tags.
Current biology : CB 1996;6(12):1543-4.
1996: Yan J X; Wilkins M R; Ou K; Gooley A A; Williams K L; Sanchez J C; Golaz O; Pasquali C; Hochstrasser D F
Large-scale amino-acid analysis for proteome studies.
Journal of chromatography. A 1996;736(1-2):291-302.
1996: Wilkins M R; Sanchez J C; Williams K L; Hochstrasser D F
Current challenges and future applications for protein maps and post-translational vector maps in proteome projects.
Electrophoresis 1996;17(5):830-8.
1996: Wilkins M R; Ou K; Appel R D; Sanchez J C; Yan J X; Golaz O; Farnsworth V; Cartier P; Hochstrasser D F; Williams K L; Gooley A A
Rapid protein identification using N-terminal "sequence tag" and amino acid analysis.
Biochemical and biophysical research communications 1996;221(3):609-13.
1996: Golaz O; Wilkins M R; Sanchez J C; Appel R D; Hochstrasser D F; Williams K L
Identification of proteins by their amino acid composition: an evaluation of the method.
Electrophoresis 1996;17(3):573-9.
1996: Sanchez J C; Golaz O; Frutiger S; Schaller D; Appel R D; Bairoch A; Hughes G J; Hochstrasser D F
The yeast SWISS-2DPAGE database.
Electrophoresis 1996;17(3):556-65.
1996: Pasquali C; Frutiger S; Wilkins M R; Hughes G J; Appel R D; Bairoch A; Schaller D; Sanchez J C; Hochstrasser D F
Two-dimensional gel electrophoresis of Escherichia coli homogenates: the Escherichia coli SWISS-2DPAGE database.
Electrophoresis 1996;17(3):547-55.
1996: Appel R D; Bairoch A; Sanchez J C; Vargas J R; Golaz O; Pasquali C; Hochstrasser D F
Federated two-dimensional electrophoresis database: a simple means of publishing two-dimensional electrophoresis data.
Electrophoresis 1996;17(3):540-6.
1996: Gravel P; Walzer C; Aubry C; Balant L P; Yersin B; Hochstrasser D F; Guimon J
New alterations of serum glycoproteins in alcoholic and cirrhotic patients revealed by high resolution two-dimensional gel electrophoresis.
Biochemical and biophysical research communications 1996;220(1):78-85.
1996: Packer N H; WIlkins M R; Golaz O; Lawson M A; Gooley A A; Hochstrasser D F; Redmond J W; Williams K L
Characterization of human plasma glycoproteins separated by two-dimensional gel electrophoresis.
Bio/technology (Nature Publishing Company) 1996;14(1):66-70.
1996: Wilkins M R; Pasquali C; Appel R D; Ou K; Golaz O; Sanchez J C; Yan J X; Gooley A A; Hughes G; Humphery-Smith I; Williams K L; Hochstrasser D F
From proteins to proteomes: large scale protein identification by two-dimensional electrophoresis and amino acid analysis.
Bio/technology (Nature Publishing Company) 1996;14(1):61-5.
1996: Appel R D; Sanchez J C; Bairoch A; Golaz O; Ravier F; Pasquali C; Hughes G J; Hochstrasser D F
The SWISS-2DPAGE database of two-dimensional polyacrylamide gel electrophoresis, its status in 1995.
Nucleic acids research 1996;24(1):180-1.
1996: Wilkins M R; Sanchez J C; Gooley A A; Appel R D; Humphery-Smith I; Hochstrasser D F; Williams K L
Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it.
Biotechnology & genetic engineering reviews 1996;13():19-50.
1995: Cossio G; Sanchez J C; Golaz O; Wettstein R; Hochstrasser D F
Spermatocytes and round spermatids of rat testis: protein patterns.
Electrophoresis 1995;16(7):1225-30.
1995: Dreher D; Vargas J R; Hochstrasser D F; Junod A F
Effects of oxidative stress and Ca2+ agonists on molecular chaperones in human umbilical vein endothelial cells.
Electrophoresis 1995;16(7):1205-14.
1995: Golaz O; Gravel P; Walzer C; Turler H; Balant L; Hochstrasser D F
Rapid detection of the main human plasma glycoproteins by two-dimensional polyacrylamide gel electrophoresis lectin affinoblotting.
Electrophoresis 1995;16(7):1187-9.
1995: Golaz O; Sanchez J C; James R W; Hochstrasser D F
Phenotyping of apolipoprotein E using immobilized pH gradient gels for one-dimensional and two-dimensional separations.
Electrophoresis 1995;16(7):1184-6.
1995: Gravel P; Sanchez J C; Walzer C; Golaz O; Hochstrasser D F; Balant L P; Hughes G J; Garcia-Sevilla J; Guimon J
Human blood platelet protein map established by two-dimensional polyacrylamide gel electrophoresis.
Electrophoresis 1995;16(7):1152-9.
1995: Sanchez J C; Appel R D; Golaz O; Pasquali C; Ravier F; Bairoch A; Hochstrasser D F
Inside SWISS-2DPAGE database.
Electrophoresis 1995;16(7):1131-51.
1995: Hochstrasser D F; Appel R D; Golaz O; Pasquali C; Sanchez J C; Bairoch A
Sharing of worldwide spread knowledge using hypermedia facilities & fast communication protocols (Mosaic and World Wide Web): the example of ExPASy.
Methods of information in medicine 1995;34(1-2):75-8.
1994: Appel R D; Sanchez J C; Bairoch A; Golaz O; Ravier F; Pasquali C; Hughes G J; Hochstrasser D F
The SWISS-2DPAGE database of two-dimensional polyacrylamide gel electrophoresis.
Nucleic acids research 1994;22(17):3581-2.
1994: Gravel P; Golaz O; Walzer C; Hochstrasser D F; Turler H; Balant L P
Analysis of glycoproteins separated by two-dimensional gel electrophoresis using lectin blotting revealed by chemiluminescence.
Analytical biochemistry 1994;221(1):66-71.
1994: Tissot J D; Schifferli J A; Hochstrasser D F; Pasquali C; Spertini F; Clément F; Frutiger S; Paquet N; Hughes G J; Schneider P
Two-dimensional polyacrylamide gel electrophoresis analysis of cryoglobulins and identification of an IgM-associated peptide.
Journal of immunological methods 1994;173(1):63-75.
1993: Appel R D; Sanchez J C; Bairoch A; Golaz O; Miu M; Vargas J R; Hochstrasser D F
SWISS-2DPAGE: a database of two-dimensional gel electrophoresis images.
Electrophoresis 1993;14(11):1232-8.
1993: Hughes G J; Frutiger S; Paquet N; Pasquali C; Sanchez J C; Tissot J D; Bairoch A; Appel R D; Hochstrasser D F
Human liver protein map: update 1993.
Electrophoresis 1993;14(11):1216-22.
1993: Walzer C; Turler H; Balant L; Golaz O; Hochstrasser D F; Monteiro M; von Wartburg J P
Determination of human alcohol dehydrogenase and acetaldehyde dehydrogenase genotypes by single strand conformation polymorphism in discontinuous buffer electrophoresis.
Electrophoresis 1993;14(7):566-9.
1993: Tissot J D; Hohlfeld P; Hochstrasser D F; Tolsa J F; Calme A; Schneider P
Clonal imbalances of plasma/serum immunoglobulin production in infants.
Electrophoresis 1993;14(3):245-7.
1993: Tissot J D; Hohlfeld P; Forestier F; Tolsa J F; Hochstrasser D F; Calame A; Plouvier E; Bossart H; Schneider P
Plasma/serum protein patterns in human fetuses and infants: a study by high-resolution two-dimensional polyacrylamide gel electrophoresis.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society 1993;3(3-4):183-90.
1992: Hochstrasser D F; Frutiger S; Paquet N; Bairoch A; Ravier F; Pasquali C; Sanchez J C; Tissot J D; Bjellqvist B; Vargas R
Human liver protein map: a reference database established by microsequencing and gel comparison.
Electrophoresis 1992;13(12):992-1001.
1992: Toussi A; Paquet N; Huber O; Frutiger S; Tissot J D; Hughes G J; Hochstrasser D F
Polypeptide marker and disease patterns found while mapping proteins in ascitis.
Journal of chromatography 1992;582(1-2):87-92.
1992: Hughes G J; Frutiger S; Paquet N; Ravier F; Pasquali C; Sanchez J C; James R; Tissot J D; Bjellqvist B; Hochstrasser D F
Plasma protein map: an update by microsequencing.
Electrophoresis 1992;13(9-10):707-14.
1992: Sanchez J C; Ravier F; Pasquali C; Frutiger S; Paquet N; Bjellqvist B; Hochstrasser D F; Hughes G J
Improving the detection of proteins after transfer to polyvinylidene difluoride membranes.
Electrophoresis 1992;13(9-10):715-7.
1992: Tissot J D; Clément F; Schifferli J A; Frei P C; Hochstrasser D F; Schneider P
Clonality of cold agglutinins in patients with hemolytic anemia: an analysis by high-resolution two-dimensional gel electrophoresis.
American journal of hematology 1992;40(3):171-5.
1992: Tissot J D; Schneider P; Hohlfeld P; Tolsa J F; Calame A; Hochstrasser D F
Monoclonal gammopathy in a 30 weeks old premature infant.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society 1992;3(2):67-8.
1991: Appel R D; Hochstrasser D F; Funk M; Vargas J R; Pellegrini C; Muller A F; Scherrer J R
The MELANIE project: from a biopsy to automatic protein map interpretation by computer.
Electrophoresis 1991;12(10):722-35.
1991: Jacot-Descombes A; Todorov K; Hochstrasser D F; Pellegrini C; Pun T
LaboImage: a workstation environment for research in image processing and analysis.
Computer applications in the biosciences : CABIOS 1991;7(2):225-32.
1991: Hochstrasser D F; Appel R D; Vargas R; Perrier R; Vurlod J F; Ravier F; Pasquali C; Funk M; Pellegrini C; Muller A F
A clinical molecular scanner: the Melanie project.
M.D. computing : computers in medical practice 1991;8(2):85-91.
1991: Tissot J D; Schneider P; James R W; Daigneault R; Hochstrasser D F
High-resolution two-dimensional protein electrophoresis of pathological plasma/serum.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society 1991;2(1):7-12.
1990: Hochstrasser D F; Funk M; Appel R D; Pun T; James R W; Hochstrasser A C; Scherrer J R; Pellegrini C; Müller A F
From biopsy to automatic diagnosis.
Schweizerische medizinische Wochenschrift 1990;120(49):1862-6.
1989: Roch C; Pun T; Hochstrasser D F; Pellegrini C
Automatic learning strategies and their application to electrophoresis analysis.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society 1989;13(5):383-91.
1988: Hochstrasser D F; Harrington M G; Hochstrasser A C; Miller M J; Merril C R
Methods for increasing the resolution of two-dimensional protein electrophoresis.
Analytical biochemistry 1988;173(2):424-35.
1988: Hochstrasser D F; Patchornik A; Merril C R
Development of polyacrylamide gels that improve the separation of proteins and their detection by silver staining.
Analytical biochemistry 1988;173(2):412-23.
1988: Pun T; Hochstrasser D F; Appel R D; Funk M; Villars-Augsburger V; Pellegrini C
Computerized classification of two-dimensional gel electrophoretograms by correspondence analysis and ascendant hierarchical clustering.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society 1988;1(1):3-9.
1988: Hochstrasser D F; Merril C R
'Catalysts' for polyacrylamide gel polymerization and detection of proteins by silver staining.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society 1988;1(1):35-40.

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