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Shirley Hodgson

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Genetic Counseling

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Pia Ostergaard; Daniela T Pilz; Michael A Simpson; Sarah Smithson; Colin G Steward; Richard C Trembath; Wesley J Woollard; Ines Martinez-Corral; Peter S Mortimer; Victoria Murday; Glen Brice; Fiona C Connell; Dimitra Dafou; Shirley Hodgson; Steve Jeffery; Russell Keenan; Tatjana Kilo; Peter Lunt; Taija Makinen; Sahar Mansour
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome).
Elina Heliövaara; Sari Tuupanen; Manuel Ahlsten; Shirley Hodgson; Ernesto De Menis; Outi Kuismin; Louise Izatt; R J McKinlay Gardner; Sadi Gundogdu; Anneke Lucassen; Johanna Arola; Anne Tuomisto; Markus Makinen; Auli Karhu; Lauri A Aaltonen
No evidence of RET germline mutations in familial pituitary adenoma.
Sahar Mansour; Fiona Connell; Colin Steward; Pia Ostergaard; Glen Brice; Sarah Smithson; Peter Lunt; Steve Jeffery; Inderjeet Dokal; Tom Vulliamy; Brenda Gibson; Shirley Hodgson; Sally Cottrell; Louise Kiely; Lorna Tinworth; Kamini Kalidas; Ghulam Mufti; Jackie Cornish; Russell Keenan; Peter Mortimer; Victoria Murday
Emberger syndrome-primary lymphedema with myelodysplasia: report of seven new cases.

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All Publications

2011: Pia Ostergaard; Daniela T Pilz; Michael A Simpson; Sarah Smithson; Colin G Steward; Richard C Trembath; Wesley J Woollard; Ines Martinez-Corral; Peter S Mortimer; Victoria Murday; Glen Brice; Fiona C Connell; Dimitra Dafou; Shirley Hodgson; Steve Jeffery; Russell Keenan; Tatjana Kilo; Peter Lunt; Taija Makinen; Sahar Mansour
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome).
Nature genetics 2011;43(10):929-31.
2011: Elina Heliövaara; Sari Tuupanen; Manuel Ahlsten; Shirley Hodgson; Ernesto De Menis; Outi Kuismin; Louise Izatt; R J McKinlay Gardner; Sadi Gundogdu; Anneke Lucassen; Johanna Arola; Anne Tuomisto; Markus Makinen; Auli Karhu; Lauri A Aaltonen
No evidence of RET germline mutations in familial pituitary adenoma.
Journal of molecular endocrinology 2011;46(1):1-8.
2010: Sahar Mansour; Fiona Connell; Colin Steward; Pia Ostergaard; Glen Brice; Sarah Smithson; Peter Lunt; Steve Jeffery; Inderjeet Dokal; Tom Vulliamy; Brenda Gibson; Shirley Hodgson; Sally Cottrell; Louise Kiely; Lorna Tinworth; Kamini Kalidas; Ghulam Mufti; Jackie Cornish; Russell Keenan; Peter Mortimer; Victoria Murday
Emberger syndrome-primary lymphedema with myelodysplasia: report of seven new cases.
American journal of medical genetics. Part A 2010;152A(9):2287-96.
2010: Helen Hanson; Shirley Hodgson
Cancer genetics and reproduction.
Best practice & research. Clinical obstetrics & gynaecology 2010;24(1):3-18.
2009: Shirley Hodgson; Adonis S Ioannides
Genetic testing in other GI diseases.
Best practice & research. Clinical gastroenterology 2009;23(2):245-56.
2008: Marianthi Georgitsi; Elina Heliövaara; Ralf Paschke; Ajith V K Kumar; Marc Tischkowitz; Outi Vierimaa; Pasi Salmela; Timo Sane; Ernesto De Menis; Serafinella P Cannavò; Sadi Gündogdu; Anneke Lucassen; Louise Izatt; Simon Aylwin; Gul Bano; Shirley Hodgson; Christian A Koch; Auli Karhu; Lauri A Aaltonen
Large genomic deletions in AIP in pituitary adenoma predisposition.
The Journal of clinical endocrinology and metabolism 2008;93(10):4146-51.
2008: Shirley Hodgson
Mechanisms of inherited cancer susceptibility.
Journal of Zhejiang University. Science. B 2008;9(1):1-4.
2007: Julian Barwell; Laurent Pangon; Anne Georgiou; Zoe Docherty; Ian Kesterton; J Ball; Richard S Camplejohn; Jonathan Berg; Abraham Aviv; J Gardner; Bernet S Kato; N Carter; D Paximadas; Tim D Spector; Shirley Hodgson
Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity?
British journal of cancer 2007;97(12):1696-700.
2007: Marianthi Georgitsi; Anniina Raitila; Auli Karhu; Rob B van der Luijt; Cora M Aalfs; Timo Sane; Outi Vierimaa; Markus Makinen; Karoliina Tuppurainen; Ralph Paschke; Oliver Gimm; Christian A Koch; Sadi Gündogdu; Anneke Lucassen; Marc Tischkowitz; Louise Izatt; Simon Aylwin; Gul Bano; Shirley Hodgson; Ernesto De Menis; Virpi Launonen; Pia Vahteristo; Lauri A Aaltonen
Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia.
The Journal of clinical endocrinology and metabolism 2007;92(8):3321-5.
2007: Julian Barwell; Laurent Pangon; Shirley Hodgson; Anne Georgiou; Ian Kesterton; T Slade; M Taylor; S J Payne; H Brinkman; J Smythe; Neil J Sebire; Ellen Solomon; Zoe Docherty; Richard S Camplejohn; Tessa Homfray; Joanna R Morris
Biallelic mutation of MSH2 in primary human cells is associated with sensitivity to irradiation and altered RAD51 foci kinetics.
Journal of medical genetics 2007;44(8):516-20.
2007: H F A Vasen; Gabriela Möslein; A Alonso; I Bernstein; L Bertario; I Blanco; John Burn; G Capella; Christoph Engel; Ian M Frayling; Waltraut Friedl; Frederik J Hes; Shirley Hodgson; Jukka-Pekka Mecklin; Pål Møller; Fokko M Nagengast; Y Parc; Laura Renkonen-Sinisalo; Julian R Sampson; Astrid T Stormorken; Juul Wijnen
Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).
Journal of medical genetics 2007;44(6):353-62.
2007: Zoe Docherty; Anne Georgiou; Caroline Langman; Ian Kesterton; Sarah Rose; Richard S Camplejohn; Jan Ball; Julian Barwell; Ruth Gilchrist; Laurent Pangon; Jonathan Berg; Shirley Hodgson
Is chromosome radiosensitivity and apoptotic response to irradiation correlated with cancer susceptibility?
International journal of radiation biology 2007;83(1):1-12.
2007: Lindsay Fraser; Sally Watts; Anna Cargill; Stephen Sutton; Shirley Hodgson
Study comparing two types of screening provision for people with von Hippel-Lindau disease.
Familial cancer 2007;6(1):103-11.
2006: Susan Shanley; Kate McReynolds; Audrey Ardern-Jones; Roger Ahern; Indrajit Fernando; John Yarnold; Gareth Evans; Diana Eccles; Shirley Hodgson; Sue Ashley; Linda Ashcroft; Andrew Tutt; Elizabeth Bancroft; Susan Short; Ian Smith; G P H Gui; Lester Barr; Andrew Baildam; Anthony Howell; Gavin Royle; Lori J Pierce; Douglas Easton; Rosalind Eeles
Acute chemotherapy-related toxicity is not increased in BRCA1 and BRCA2 mutation carriers treated for breast cancer in the United Kingdom.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(23):7033-8.
2006: Susan Shanley; Kate McReynolds; Audrey Ardern-Jones; Roger Ahern; Indrajit Fernando; John Yarnold; Gareth Evans; Diana Eccles; Shirley Hodgson; Sue Ashley; Linda Ashcroft; Andrew Tutt; Elizabeth Bancroft; Susan Short; G P H Gui; Lester Barr; Andrew Baildam; Anthony Howell; Gavin Royle; Lori J Pierce; Douglas Easton; Rosalind Eeles
Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(23):7025-32.
2006: H Brinkman; Julian Barwell; S Rose; Lorna Tinworth; N Sodha; C Langman; L Brooks; S Payne; Shannon Fisher; Andrew Rowan; I Tomlinson; Shirley Hodgson
Evidence against a major genetic basis for combined breast and colorectal cancer susceptibility.
Clinical genetics 2006;70(6):526-9.
2006: Richard S Camplejohn; Shirley Hodgson; N Carter; Bernet S Kato; Tim D Spector
Heritability of DNA-damage-induced apoptosis and its relationship with age in lymphocytes from female twins.
British journal of cancer 2006;95(4):520-4.
2006: Gillian Mitchell; Antonis C Antoniou; Ruth Warren; Susan Peock; Judith Brown; Russell Davies; Jenny Mattison; Margaret Cook; Iqbal Warsi; D G R Evans; Diana Eccles; Fiona Douglas; Joan Paterson; Shirley Hodgson; Louise Izatt; Trevor Cole; Lucy Burgess; Rosalind Eeles; Douglas F Easton
Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers.
Cancer research 2006;66(3):1866-72.
2005: Nicholas Hearle; Ian Tomlinson; Wendy Lim; Victoria Murday; Edwin Swarbrick; Guan Lim; Robin Phillips; Peter Lee; John O'Donohue; Richard C Trembath; Patrick J Morrison; Andrew Norman; Rohan Taylor; Shirley Hodgson; Anneke Lucassen; richard Houlston
Sequence changes in predicted promoter elements of STK11/LKB1 are unlikely to contribute to Peutz-Jeghers syndrome.
BMC genomics 2005;6():38.
2004: Tamar Stermer; Shirley Hodgson; Fred Kavalier; Sally Watts; Roger Jones
Patients' and professionals' opinions of services for people at an increased risk of colorectal cancer: an exploratory qualitative study.
Familial cancer 2004;3(1):49-53.
2004: Victoria Murday; R Pears; J Ball; Rosalind Eeles; Shirley Hodgson
An audit of screening for familial breast cancer before 50 years in the South Thames Region - have we got it right?
Familial cancer 2004;3(1):29-34.
2004: Christine Mant; Shirley Hodgson; Richard Hobday; Corrado D'Arrigo; John Cason
A viral aetiology for breast cancer: time to re-examine the postulate.
Intervirology 2004;47(1):2-13.
2003: Päivi Laiho; Tuija Hienonen; Auli Karhu; Lara Lipton; Yan Aalto; Huw J W Thomas; Karin Birkenkamp-Demtroder; Shirley Hodgson; Reijo Salovaara; Jukka-Pekka Mecklin; Heikki Järvinen; Sakari Knuutila; Stephanie Halford; Torben F Ørntoft; Ian Tomlinson; Virpi Launonen; richard Houlston; Lauri A Aaltonen
Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.
Oncogene 2003;22(14):2206-14.
2003: L Fraser; S Bramald; C Chapman; C Chu; V Cornelius; Fiona Douglas; Anneke Lucassen; A Nehammer; S Sutton; M Trivella; Shirley Hodgson
What motivates interest in attending a familial cancer genetics clinic?
Familial cancer 2003;2(3-4):159-68.
2003: Sara Levene; Gillian Scott; Patricia Price; Jeremy Sanderson; Helen Evans; Claire Taylor; Sylvia Bass; Cathryn Lewis; Shirley Hodgson
Does the occurrence of certain rare cancers indicate an inherited cancer susceptibility?
Familial cancer 2003;2(1):15-25.
2002: Alison Bish; Stephen Sutton; Christine Jacobs; Sara Levene; Amanda Ramirez; Shirley Hodgson
No news is (not necessarily) good news: impact of preliminary results for BRCA1 mutation searches.
Genetics in medicine : official journal of the American College of Medical Genetics 2002;4(5):353-8.
2002: Christopher Groves; Hanan Lamlum; Michael Crabtree; Jill Williamson; Claire Taylor; Sylvia Bass; Darren Cuthbert-Heavens; Shirley Hodgson; Robin Phillips; Ian Tomlinson
Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.
The American journal of pathology 2002;160(6):2055-61.
2002: Melissa A Brown; Li-Jan Lo; Aurélie Catteau; Chun-Fang Xu; Geoffrey J Lindeman; Shirley Hodgson; Ellen Solomon
Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1:psiBRCA1 recombination.
Human mutation 2002;19(4):435-42.
2002: Oliver Sieber; Hanan Lamlum; Michael Crabtree; Andrew J Rowan; Ella Barclay; Lara Lipton; Shirley Hodgson; Huw J W Thomas; Kay Neale; R K S Phillips; Susan M Farrington; Malcolm G Dunlop; H J Mueller; Marie-Luise Bisgaard; S Bulow; Paulo Fidalgo; Cristina Albuquerque; Maria Irene Scarano; Walter Bodmer; Ian P M Tomlinson; Karl Heinimann
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2954-8.
2002: Alison Bish; S Sutton; C Jacobs; Sara Levene; Amanda Ramirez; Shirley Hodgson
Changes in psychological distress after cancer genetic counselling: a comparison of affected and unaffected women.
British journal of cancer 2002;86(1):43-50.
2001: D Eccles; P Simmonds; J Goddard; M Coultas; Shirley Hodgson; Fiona Lalloo; G Evans; N Haites
Familial breast cancer: an investigation into the outcome of treatment for early stage disease.
Familial cancer 2001;1(2):65-72.
2000: D Ellis; J Greenman; Shirley Hodgson; S McCall; Fiona Lalloo; J Cameron; Louise Izatt; G Scott; C Jacobs; S Watts; W Chorley; C Perrett; K Macdermot; S Mohammed; G Evans; Christopher G Mathew
Low prevalence of germline BRCA1 mutations in early onset breast cancer without a family history.
Journal of medical genetics 2000;37(10):792-4.
2000: Kelly Woodford-Richens; J Williamson; S Bevan; J Young; B Leggett; Ian M Frayling; Y Thway; Shirley Hodgson; J C Kim; T Iwama; Marco R Novelli; Denise Sheer; Richard Poulsom; N Wright; richard Houlston; Ian Tomlinson
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium.
Cancer research 2000;60(9):2477-82.
2000: P Warburton; G Baird; W Chen; K Morris; B W Jacobs; Shirley Hodgson; Zoe Docherty
Support for linkage of autism and specific language impairment to 7q3 from two chromosome rearrangements involving band 7q31.
American journal of medical genetics 2000;96(2):228-34.
1999: Louise Izatt; J Greenman; Shirley Hodgson; D Ellis; S Watts; G Scott; C Jacobs; R Liebmann; Marketa Zvelebil; Christopher G Mathew; Ellen Solomon
Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer.
Genes, chromosomes & cancer 1999;26(4):286-94.
1999: Pål Møller; G Evans; Neva E Haites; H F A Vasen; Marta M Reis; Elaine Anderson; Jaran Apold; Shirley Hodgson; Diana Eccles; H Olsson; D Stoppa-Lyonnet; Jenny Chang-Claude; Patrick J Morrison; G Bevilacqua; Ketil Heimdal; Lovise Maehle; Fiona Lalloo; Helen Gregory; PE Preece; Ake Borg; NC Nevin; MA Caligo; C Michael Steel
Guidelines for follow-up of women at high risk for inherited breast cancer: consensus statement from the Biomed 2 Demonstration Programme on Inherited Breast Cancer.
Disease markers 1999;15(1-3):207-11.
1999: Patrick J Morrison; C Michael Steel; H F A Vasen; Diana Eccles; D G R Evans; Pål Møller; Shirley Hodgson; D Stoppa-Lyonnet; Jenny Chang-Claude; MA Caligo; Edith Olah; Neva E Haites; NC Nevin
Insurance implications for individuals with a high risk of breast and ovarian cancer in Europe.
Disease markers 1999;15(1-3):159-65.
1999: D G R Evans; E Anderson; Fiona Lalloo; H F A Vasen; M Beckmann; Diana Eccles; Shirley Hodgson; Pål Møller; Jenny Chang-Claude; P Morrison; D Stoppa-Lyonnet; M Steel; Neva E Haites
Utilisation of prophylactic mastectomy in 10 European centres.
Disease markers 1999;15(1-3):148-51.
1999: M Steel; E Smyth; H F A Vasen; Diana Eccles; G Evans; Pål Møller; Shirley Hodgson; D Stoppa-Lyonnet; Jenny Chang-Claude; MA Caligo; P Morrison; Neva E Haites
Ethical, social and economic issues in familial breast cancer: a compilation of views from the E.C. Biomed II Demonstration Project.
Disease markers 1999;15(1-3):125-31.
1999: Jenny Chang-Claude; H Becher; MA Caligo; Diana Eccles; G Evans; Neva E Haites; Shirley Hodgson; Pål Møller; Bernhard H F Weber; D Stoppa-Lyonnet
Risk estimation as a decision-making tool for genetic analysis of the breast cancer susceptibility genes. EC Demonstration Project on Familial Breast Cancer.
Disease markers 1999;15(1-3):53-65.
1999: Shirley Hodgson; BJ Milner; I Brown; G Bevilacqua; Jenny Chang-Claude; Diana Eccles; G Evans; Helen Gregory; Pål Møller; P Morrison; M Steel; D Stoppa-Lyonnet; H F A Vasen; Neva E Haites
Cancer genetics services in Europe.
Disease markers 1999;15(1-3):3-13.
1999: S Bevan; Kelly Woodford-Richens; P Rozen; Charis Eng; J Young; M Dunlop; Kay Neale; Robin Phillips; D Markie; MA Rodriguez-Bigas; B Leggett; E Sheridan; Shirley Hodgson; T Iwama; Diana Eccles; Walter Bodmer; richard Houlston; Ian Tomlinson
Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome.
Gut 1999;45(3):406-8.
1999: Ian Tomlinson; Nazneen Rahman; Ian M Frayling; J Mangion; Rita Barfoot; Rifat A Hamoudi; Sheila Seal; J M A Northover; Huw J W Thomas; Kay Neale; Shirley Hodgson; Ian C Talbot; richard Houlston; Michael R Stratton
Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.
Gastroenterology 1999;116(4):789-95.
1999: Aurélie Catteau; Chun-Fang Xu; Melissa A Brown; Shirley Hodgson; J Greenman; Christopher G Mathew; Alison M Dunning; Ellen Solomon
Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions.
British journal of cancer 1999;79(5-6):759-63.
1998: H F A Vasen; Neva E Haites; D G R Evans; C Michael Steel; Pål Møller; Shirley Hodgson; Diana Eccles; P Morrison; D Stoppa Lyonet; Jenny Chang-Claude; MA Caligo
Current policies for surveillance and management in women at risk of breast and ovarian cancer: a survey among 16 European family cancer clinics. European Familial Breast Cancer Collaborative Group.
European journal of cancer (Oxford, England : 1990) 1998;34(12):1922-6.
1998: richard Houlston; S Bevan; A Williams; J Young; M Dunlop; P Rozen; Charis Eng; D Markie; Kelly Woodford-Richens; MA Rodriguez-Bigas; B Leggett; Kay Neale; Robin Phillips; E Sheridan; Shirley Hodgson; T Iwama; Diana Eccles; Walter Bodmer; Ian Tomlinson
Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.
Human molecular genetics 1998;7(12):1907-12.
1998: J Greenman; S Mohammed; D Ellis; S Watts; G Scott; Louise Izatt; D Barnes; Ellen Solomon; Shirley Hodgson; Christopher G Mathew
Identification of missense and truncating mutations in the BRCA1 gene in sporadic and familial breast and ovarian cancer.
Genes, chromosomes & cancer 1998;21(3):244-9.
1998: S Olschwang; D Markie; Sheila Seal; Kay Neale; Robin Phillips; SE Cottrell; I Ellis; Shirley Hodgson; P Zauber; A Spigelman; T Iwama; S Loff; C McKeown; C Marchese; J Sampson; S Davies; Ian C Talbot; J Wyke; G Thomas; Walter Bodmer; Akseli Hemminki; E Avizienyte; Albert de La Chapelle; L Aaltonen; Ian Tomlinson
Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3.
Journal of medical genetics 1998;35(1):42-4.
1997: Chun-Fang Xu; JA Chambers; Hans Nicolai; Melissa A Brown; Y Hujeirat; S Mohammed; Shirley Hodgson; David P Kelsell; Nigel K Spurr; Tim BISHOP; Ellen Solomon
Mutations and alternative splicing of the BRCA1 gene in UK breast/ovarian cancer families.
Genes, chromosomes & cancer 1997;18(2):102-10.
1996: H Iwase; J M Greenman; DM Barnes; Shirley Hodgson; LG Bobrow; Christopher G Mathew
Sequence variants of the estrogen receptor (ER) gene found in breast cancer patients with ER negative and progesterone receptor positive tumors.
Cancer letters 1996;108(2):179-84.
1995: H Iwase; J M Greenman; DM Barnes; LG Bobrow; Shirley Hodgson; Christopher G Mathew
Loss of heterozygosity of the oestrogen receptor gene in breast cancer.
British journal of cancer 1995;71(3):448-50.
1994: J Smith-Ravin; Kevin Pack; Shirley Hodgson; S K Tay; Robin Phillips; W Bodmer
APC mutation associated with late onset of familial adenomatous polyposis.
Journal of medical genetics 1994;31(11):888-90.
1992: DM Barnes; Andrew M Hanby; Cheryl E Gillett; S Mohammed; Shirley Hodgson; LG Bobrow; I M Leigh; T Purkis; C MacGeoch; Nigel K Spurr
Abnormal expression of wild type p53 protein in normal cells of a cancer family patient.
Lancet 1992;340(8814):259-63.