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Jan Hoeijmakers

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Pothof Joris; Verkaik Nicole S; Hoeijmakers Jan H J; van Gent Dik C
MicroRNA responses and stress granule formation modulate the DNA damage response.
Giglia-Mari Giuseppina; Theil Arjan F; Mari Pierre-Olivier; Mourgues Sophie; Nonnekens Julie; Andrieux Lise O; de Wit Jan; Miquel Catherine; Wijgers Nils; Maas Alex; Fousteri Maria; Hoeijmakers Jan H J; Vermeulen Wim
Differentiation driven changes in the dynamic organization of Basal transcription initiation.
Hoeijmakers Jan H J
DNA damage, aging, and cancer.

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All Publications

2009: Pothof Joris; Verkaik Nicole S; Hoeijmakers Jan H J; van Gent Dik C
MicroRNA responses and stress granule formation modulate the DNA damage response.
Cell cycle (Georgetown, Tex.) 2009;8(21):3462-8.
2009: Giglia-Mari Giuseppina; Theil Arjan F; Mari Pierre-Olivier; Mourgues Sophie; Nonnekens Julie; Andrieux Lise O; de Wit Jan; Miquel Catherine; Wijgers Nils; Maas Alex; Fousteri Maria; Hoeijmakers Jan H J; Vermeulen Wim
Differentiation driven changes in the dynamic organization of Basal transcription initiation.
PLoS biology 2009;7(10):e1000220.
2009: Hoeijmakers Jan H J
DNA damage, aging, and cancer.
The New England journal of medicine 2009;361(15):1475-85.
2009: van Ginhoven Tessa M; Mitchell James R; Verweij Marielle; Hoeijmakers Jan H J; Ijzermans Jan N M; de Bruin Ron W F
The use of preoperative nutritional interventions to protect against hepatic ischemia-reperfusion injury.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009;15(10):1183-91.
2009: Pothof Joris; Verkaik Nicole S; van IJcken Wilfred; Wiemer Erik A C; Ta Van T B; van der Horst Gijsbertus T J; Jaspers Nicolaas G J; van Gent Dik C; Hoeijmakers Jan H J; Persengiev Stephan P
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response.
The EMBO journal 2009;28(14):2090-9.
2009: Nishi Ryotaro; Alekseev Sergey; Dinant Christoffel; Hoogstraten Deborah; Houtsmuller Adriaan B; Hoeijmakers Jan H J; Vermeulen Wim; Hanaoka Fumio; Sugasawa Kaoru
UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells.
DNA repair 2009;8(6):767-76.
2009: Garinis George A; Uittenboogaard Lieneke M; Stachelscheid Heike; Fousteri Maria; van Ijcken Wilfred; Breit Timo M; van Steeg Harry; Mullenders Leon H F; van der Horst Gijsbertus T J; Brüning Jens C; Niessen Carien M; Hoeijmakers Jan H J; Schumacher Björn
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Nature cell biology 2009;11(5):604-15.
2009: Susa Denis; Mitchell James R; Verweij Marielle; van de Ven Marieke; Roest Henk; van den Engel Sandra; Bajema Ingeborg; Mangundap Kirsten; Ijzermans Jan N M; Hoeijmakers Jan H J; de Bruin Ron W F
Congenital DNA repair deficiency results in protection against renal ischemia reperfusion injury in mice.
Aging cell 2009;8(2):192-200.
2009: Inagaki Akiko; van Cappellen Wiggert A; van der Laan Roald; Houtsmuller Adriaan B; Hoeijmakers Jan H J; Grootegoed J Anton; Baarends Willy M
Dynamic localization of human RAD18 during the cell cycle and a functional connection with DNA double-strand break repair.
DNA repair 2009;8(2):190-201.
2008: Alekseev Sergey; Luijsterburg Martijn S; Pines Alex; Geverts Bart; Mari Pierre-Olivier; Giglia-Mari Giuseppina; Lans Hannes; Houtsmuller Adriaan B; Mullenders Leon H F; Hoeijmakers Jan H J; Vermeulen Wim
Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage.
Molecular and cellular biology 2008;28(24):7402-13.
2008: Garinis George A; van der Horst Gijsbertus T J; Vijg Jan; Hoeijmakers Jan H J
DNA damage and ageing: new-age ideas for an age-old problem.
Nature cell biology 2008;10(11):1241-7.
2008: de Waard Harm; Sonneveld Edwin; de Wit Jan; Esveldt-van Lange Rebecca; Hoeijmakers Jan H J; Vrieling Harry; van der Horst Gijsbertus T J
Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.
DNA repair 2008;7(10):1659-69.
2008: Hoogstraten Deborah; Bergink Steven; Ng Jessica M Y; Verbiest Vincent H M; Luijsterburg Martijn S; Geverts Bart; Raams Anja; Dinant Christoffel; Hoeijmakers Jan H J; Vermeulen Wim; Houtsmuller Adriaan B
Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC.
Journal of cell science 2008;121(Pt 17):2850-9.
2008: Roche Y; Zhang D; Segers-Nolten G M J; Vermeulen W; Wyman C; Sugasawa K; Hoeijmakers J; Otto C
Fluorescence correlation spectroscopy of the binding of nucleotide excision repair protein XPC-hHr23B with DNA substrates.
Journal of fluorescence 2008;18(5):987-95.
2008: Motegi Akira; Liaw Hung-Jiun; Lee Kyoo-Young; Roest Henk P; Maas Alex; Wu Xiaoli; Moinova Helen; Markowitz Sanford D; Ding Hao; Hoeijmakers Jan H J; Myung Kyungjae
Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12411-6.
2008: Ahmad Anwaar; Robinson Andria Rasile; Duensing Anette; van Drunen Ellen; Beverloo H Berna; Weisberg David B; Hasty Paul; Hoeijmakers Jan H J; Niedernhofer Laura J
ERCC1-XPF endonuclease facilitates DNA double-strand break repair.
Molecular and cellular biology 2008;28(16):5082-92.
2008: Melis Joost P M; Wijnhoven Susan W P; Beems Rudolf B; Roodbergen Marianne; van den Berg Jolanda; Moon Hojin; Friedberg Errol; van der Horst Gijsbertus T J; Hoeijmakers Jan H J; Vijg Jan; van Steeg Harry
Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes.
Cancer research 2008;68(5):1347-53.
2008: Das Devashish; Tripsianes Konstantinos; Jaspers Nicolaas G J; Hoeijmakers Jan H J; Kaptein Robert; Boelens Rolf; Folkers Gert E
The HhH domain of the human DNA repair protein XPF forms stable homodimers.
Proteins 2008;70(4):1551-63.
2008: Schumacher Björn; Garinis George A; Hoeijmakers Jan H J
Age to survive: DNA damage and aging.
Trends in genetics : TIG 2008;24(2):77-85.
2008: Schumacher Björn; van der Pluijm Ingrid; Moorhouse Michael J; Kosteas Theodore; Robinson Andria Rasile; Suh Yousin; Breit Timo M; van Steeg Harry; Niedernhofer Laura J; van Ijcken Wilfred; Bartke Andrzej; Spindler Stephen R; Hoeijmakers Jan H J; van der Horst Gijsbertus T J; Garinis George A
Delayed and accelerated aging share common longevity assurance mechanisms.
PLoS genetics 2008;4(8):e1000161.
2007: Hoeijmakers Jan H J
Genome maintenance mechanisms are critical for preventing cancer as well as other aging-associated diseases.
Mechanisms of ageing and development 2007;128(7-8):460-2.
2007: Rossi Derrick J; Bryder David; Seita Jun; Nussenzweig Andre; Hoeijmakers Jan; Weissman Irving L
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Nature 2007;447(7145):725-9.
2007: Jaspers Nicolaas G J; Raams Anja; Silengo Margherita Cirillo; Wijgers Nils; Niedernhofer Laura J; Robinson Andria Rasile; Giglia-Mari Giuseppina; Hoogstraten Deborah; Kleijer Wim J; Hoeijmakers Jan H J; Vermeulen Wim
First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure.
American journal of human genetics 2007;80(3):457-66.
2007: Gorgels Theo G M F; van der Pluijm Ingrid; Brandt Renata M C; Garinis George A; van Steeg Harry; van den Aardweg Gerard; Jansen Gerard H; Ruijter Jan M; Bergen Arthur A B; van Norren Dirk; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome.
Molecular and cellular biology 2007;27(4):1433-41.
2007: van der Pluijm Ingrid; Garinis George A; Brandt Renata M C; Gorgels Theo G M F; Wijnhoven Susan W; Diderich Karin E M; de Wit Jan; Mitchell James R; van Oostrom Conny; Beems Rudolf; Niedernhofer Laura J; Velasco Susana; Friedberg Errol C; Tanaka Kiyoji; van Steeg Harry; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
PLoS biology 2007;5(1):e2.
2007: van Apeldoorn Aart A; de Boer Jan; van Steeg Harry; Hoeijmakers Jan H J; Otto Cees; van Blitterswijk Clemens A
Physicochemical composition of osteoporotic bone in the trichothiodystrophy premature aging mouse determined by confocal Raman microscopy.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(1):34-40.
2007: van de Ven Marieke; Andressoo Jaan-Olle; Holcomb Valerie B; Hasty Paul; Suh Yousin; van Steeg Harry; Garinis George A; Hoeijmakers Jan H J; Mitchell James R
Extended longevity mechanisms in short-lived progeroid mice: identification of a preservative stress response associated with successful aging.
Mechanisms of ageing and development 2007;128(1):58-63.
2006: Niedernhofer Laura J; Garinis George A; Raams Anja; Lalai Astrid S; Robinson Andria Rasile; Appeldoorn Esther; Odijk Hanny; Oostendorp Roos; Ahmad Anwaar; van Leeuwen Wibeke; Theil Arjan F; Vermeulen Wim; van der Horst Gijsbertus T J; Meinecke Peter; Kleijer Wim J; Vijg Jan; Jaspers Nicolaas G J; Hoeijmakers Jan H J
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
Nature 2006;444(7122):1038-43.
2006: van de Ven Marieke; Andressoo Jaan-Olle; Holcomb Valerie B; von Lindern Marieke; Jong Willeke M C; De Zeeuw Chris I; Suh Yousin; Hasty Paul; Hoeijmakers Jan H J; van der Horst Gijsbertus T J; Mitchell James R
Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice.
PLoS genetics 2006;2(12):e192.
2006: Andressoo Jaan-Olle; Hoeijmakers Jan H J; Mitchell James R
Nucleotide excision repair disorders and the balance between cancer and aging.
Cell cycle (Georgetown, Tex.) 2006;5(24):2886-8.
2006: Zotter Angelika; Luijsterburg Martijn S; Warmerdam Daniël O; Ibrahim Shehu; Nigg Alex; van Cappellen Wiggert A; Hoeijmakers Jan H J; van Driel Roel; Vermeulen Wim; Houtsmuller Adriaan B
Recruitment of the nucleotide excision repair endonuclease XPG to sites of UV-induced dna damage depends on functional TFIIH.
Molecular and cellular biology 2006;26(23):8868-79.
2006: Jans Judith; Garinis George A; Schul Wouter; van Oudenaren Adri; Moorhouse Michael; Smid Marcel; Sert Yurda-Gul; van der Velde Albertina; Rijksen Yvonne; de Gruijl Frank R; van der Spek Peter J; Yasui Akira; Hoeijmakers Jan H J; Leenen Pieter J M; van der Horst Gijsbertus T J
Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancer.
Molecular and cellular biology 2006;26(22):8515-26.
2006: Andressoo Jaan-Olle; Jans Judith; de Wit Jan; Coin Frederic; Hoogstraten Deborah; van de Ven Marieke; Toussaint Wendy; Huijmans Jan; Thio H Bing; van Leeuwen Wibeke J; de Boer Jan; Egly Jean-Marc; Hoeijmakers Jan H J; van der Horst Gijsbertus T J; Mitchell James R
Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.
PLoS biology 2006;4(10):e322.
2006: Bergink Steven; Severijnen Lies-Anne; Wijgers Nils; Sugasawa Kaoru; Yousaf Humaira; Kros Johan M; van Swieten John; Oostra Ben A; Hoeijmakers Jan H; Vermeulen Wim; Willemsen Rob
The DNA repair-ubiquitin-associated HR23 proteins are constituents of neuronal inclusions in specific neurodegenerative disorders without hampering DNA repair.
Neurobiology of disease 2006;23(3):708-16.
2006: Andressoo Jaan-Olle; Mitchell James R; de Wit Jan; Hoogstraten Deborah; Volker Marcel; Toussaint Wendy; Speksnijder Ewoud; Beems Rudolph B; van Steeg Harry; Jans Judith; de Zeeuw Chris I; Jaspers Nicolaas G J; Raams Anja; Lehmann Alan R; Vermeulen Wim; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria.
Cancer cell 2006;10(2):121-32.
2006: Giglia-Mari Giuseppina; Miquel Catherine; Theil Arjan F; Mari Pierre-Olivier; Hoogstraten Deborah; Ng Jessica M Y; Dinant Christoffel; Hoeijmakers Jan H J; Vermeulen Wim
Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells.
PLoS biology 2006;4(6):e156.
2006: Bergink Steven; Salomons Florian A; Hoogstraten Deborah; Groothuis Tom A M; de Waard Harm; Wu Junxin; Yuan Li; Citterio Elisabetta; Houtsmuller Adriaan B; Neefjes Jacques; Hoeijmakers Jan H J; Vermeulen Wim; Dantuma Nico P
DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A.
Genes & development 2006;20(10):1343-52.
2006: Dollé Martijn E T; Busuttil Rita A; Garcia Ana Maria; Wijnhoven Susan; van Drunen Ellen; Niedernhofer Laura J; van der Horst Gijsbertus; Hoeijmakers Jan H J; van Steeg Harry; Vijg Jan
Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.
Mutation research 2006;596(1-2):22-35.
2006: Lans Hannes; Hoeijmakers Jan H J
Cell biology: ageing nucleus gets out of shape.
Nature 2006;440(7080):32-4.
2006: Martomo Stella A; Yang William W; Vaisman Alexandra; Maas Alex; Yokoi Masayuki; Hoeijmakers Jan H; Hanaoka Fumio; Woodgate Roger; Gearhart Patricia J
Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.
DNA repair 2006;5(3):392-8.
2005: Niedernhofer Laura J; Lalai Astrid S; Hoeijmakers Jan H J
Fanconi anemia (cross)linked to DNA repair.
Cell 2005;123(7):1191-8.
2005: Tripsianes Konstantinos; Folkers Gert; Ab Eiso; Das Devashish; Odijk Hanny; Jaspers Nicolaas G J; Hoeijmakers Jan H J; Kaptein Robert; Boelens Rolf
The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair.
Structure (London, England : 1993) 2005;13(12):1849-58.
2005: Garinis George A; Mitchell James R; Moorhouse Michael J; Hanada Katsuhiro; de Waard Harm; Vandeputte Dimitri; Jans Judith; Brand Karl; Smid Marcel; van der Spek Peter J; Hoeijmakers Jan H J; Kanaar Roland; van der Horst Gijsbertus T J
Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks.
The EMBO journal 2005;24(22):3952-62.
2005: Backendorf Claude; de Wit Jan; van Oosten Marijke; Stout Gerdine J; Mitchell James R; Borgstein Anne-Marijke; van der Horst Gijsbertus T; de Gruijl Frank R; Brouwer Jaap; Mullenders Leon H F; Hoeijmakers Jan H J
Repair characteristics and differentiation propensity of long-term cultures of epidermal keratinocytes derived from normal and NER-deficient mice.
DNA repair 2005;4(11):1325-36.
2005: Wijnhoven Susan W P; Beems Rudolf B; Roodbergen Marianne; van den Berg Jolanda; Lohman Paul H M; Diderich Karin; van der Horst Gijsbertus T J; Vijg Jan; Hoeijmakers Jan H J; van Steeg Harry
Accelerated aging pathology in ad libitum fed Xpd(TTD) mice is accompanied by features suggestive of caloric restriction.
DNA repair 2005;4(11):1314-24.
2005: Andressoo J O; Hoeijmakers J H J
Transcription-coupled repair and premature ageing.
Mutation research 2005;577(1-2):179-94.
2005: Compe Emmanuel; Drané Pascal; Laurent Camille; Diderich Karin; Braun Cathy; Hoeijmakers Jan H J; Egly Jean-Marc
Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.
Molecular and cellular biology 2005;25(14):6065-76.
2005: Prasher Joanna M; Lalai Astrid S; Heijmans-Antonissen Claudia; Ploemacher Robert E; Hoeijmakers Jan H J; Touw Ivo P; Niedernhofer Laura J
Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice.
The EMBO journal 2005;24(4):861-71.
2005: Laan Roald; Baarends Willy M; Wassenaar Evelyne; Roest Henk P; Hoeijmakers Jan H J; Grootegoed J Anton
Expression and possible functions of DNA lesion bypass proteins in spermatogenesis.
International journal of andrology 2005;28(1):1-15.
2005: Baarends Willy M; Wassenaar Evelyne; van der Laan Roald; Hoogerbrugge Jos; Sleddens-Linkels Esther; Hoeijmakers Jan H J; de Boer Peter; Grootegoed J Anton
Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis.
Molecular and cellular biology 2005;25(3):1041-53.
2005: Essers Jeroen; van Cappellen Wiggert A; Theil Arjan F; van Drunen Ellen; Jaspers Nicolaas G J; Hoeijmakers Jan H J; Wyman Claire; Vermeulen Wim; Kanaar Roland
Dynamics of relative chromosome position during the cell cycle.
Molecular biology of the cell 2005;16(2):769-75.
2005: Beerens Nancy; Hoeijmakers Jan H J; Kanaar Roland; Vermeulen Wim; Wyman Claire
The CSB protein actively wraps DNA.
The Journal of biological chemistry 2005;280(6):4722-9.
2005: Jans Judith; Schul Wouter; Sert Yurda-Gul; Rijksen Yvonne; Rebel Heggert; Eker Andre P M; Nakajima Satoshi; van Steeg Harry; de Gruijl Frank R; Yasui Akira; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Powerful skin cancer protection by a CPD-photolyase transgene.
Current biology : CB 2005;15(2):105-15.
2005: Andressoo Jaan-Olle; Hoeijmakers Jan H J; de Waard Harm
Nucleotide excision repair and its connection with cancer and ageing.
Advances in experimental medicine and biology 2005;570():45-83.
2004: Moné Martijn J; Bernas Tytus; Dinant Christoffel; Goedvree Feliks A; Manders Erik M M; Volker Marcel; Houtsmuller Adriaan B; Hoeijmakers Jan H J; Vermeulen Wim; van Driel Roel
In vivo dynamics of chromatin-associated complex formation in mammalian nucleotide excision repair.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(45):15933-7.
2004: van der Laan Roald; Uringa Evert-Jan; Wassenaar Evelyne; Hoogerbrugge Jos W; Sleddens Esther; Odijk Hanny; Roest Henk P; de Boer Peter; Hoeijmakers Jan H J; Grootegoed J Anton; Baarends Willy M
Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase.
Journal of cell science 2004;117(Pt 21):5023-33.
2004: Okuda Yuki; Nishi Ryotaro; Ng Jessica M Y; Vermeulen Wim; van der Horst Gijsbertus T J; Mori Toshio; Hoeijmakers Jan H J; Hanaoka Fumio; Sugasawa Kaoru
Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex.
DNA repair 2004;3(10):1285-95.
2004: de Waard Harm; de Wit Jan; Andressoo Jaan-Olle; van Oostrom Conny T M; Riis Bente; Weimann Allan; Poulsen Henrik E; van Steeg Harry; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage.
Molecular and cellular biology 2004;24(18):7941-8.
2004: Budzowska Magda; Jaspers Iris; Essers Jeroen; de Waard Harm; van Drunen Ellen; Hanada Katsuhiro; Beverloo Berna; Hendriks Rudolf W; de Klein Annelies; Kanaar Roland; Hoeijmakers Jan H; Maas Alex
Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.
The EMBO journal 2004;23(17):3548-58.
2004: Schrader Carol E; Vardo Joycelyn; Linehan Erin; Twarog Michael Z; Niedernhofer Laura J; Hoeijmakers Jan H J; Stavnezer Janet
Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions.
The Journal of experimental medicine 2004;200(3):321-30.
2004: van den Boom Vincent; Citterio Elisabetta; Hoogstraten Deborah; Zotter Angelika; Egly Jean-Marc; van Cappellen Wiggert A; Hoeijmakers Jan H J; Houtsmuller Adriaan B; Vermeulen Wim
DNA damage stabilizes interaction of CSB with the transcription elongation machinery.
The Journal of cell biology 2004;166(1):27-36.
2004: Giglia-Mari Giuseppina; Coin Frederic; Ranish Jeffrey A; Hoogstraten Deborah; Theil Arjan; Wijgers Nils; Jaspers Nicolaas G J; Raams Anja; Argentini Manuela; van der Spek P J; Botta Elena; Stefanini Miria; Egly Jean-Marc; Aebersold Ruedi; Hoeijmakers Jan H J; Vermeulen Wim
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A.
Nature genetics 2004;36(7):714-9.
2004: Niedernhofer Laura J; Odijk Hanny; Budzowska Magda; van Drunen Ellen; Maas Alex; Theil Arjan F; de Wit Jan; Jaspers N G J; Beverloo H Berna; Hoeijmakers Jan H J; Kanaar Roland
The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks.
Molecular and cellular biology 2004;24(13):5776-87.
2004: Roest Henk P; Baarends Willy M; de Wit Jan; van Klaveren Jan W; Wassenaar Evelyne; Hoogerbrugge Jos W; van Cappellen Wiggert A; Hoeijmakers Jan H J; Grootegoed J Anton
The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.
Molecular and cellular biology 2004;24(12):5485-95.
2003: Zhu Xu-Dong; Niedernhofer Laura; Kuster Bernhard; Mann Matthias; Hoeijmakers Jan H J; de Lange Titia
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes.
Molecular cell 2003;12(6):1489-98.
2003: Weterings Eric; Verkaik Nicole S; Brüggenwirth Hennie T; Hoeijmakers Jan H J; van Gent Dik C
The role of DNA dependent protein kinase in synapsis of DNA ends.
Nucleic acids research 2003;31(24):7238-46.
2003: Diderich Karin E M; Hoeijmakers Jan H J; van Leeuwen Johannes P T M
Accelerated bone aging in the trichothiodystrophy mouse model.
The journals of gerontology. Series A, Biological sciences and medical sciences 2003;58(11):969.
2003: Kölgen Wendy; van Steeg Harry; van der Horst Gijsbertus T J; Hoeijmakers Jan H J; van Vloten Willem A; de Gruijl Frank R; Garssen Johan
Association of transcription-coupled repair but not global genome repair with ultraviolet-B-induced Langerhans cell depletion and local immunosuppression.
The Journal of investigative dermatology 2003;121(4):751-6.
2003: Rademakers Suzanne; Volker Marcel; Hoogstraten Deborah; Nigg Alex L; Moné Martijn J; Van Zeeland Albert A; Hoeijmakers Jan H J; Houtsmuller Adriaan B; Vermeulen Wim
Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions.
Molecular and cellular biology 2003;23(16):5755-67.
2003: Arnaudeau-Bégard Catherine; Brellier Florence; Chevallier-Lagente Odile; Hoeijmakers Jan; Bernerd Françoise; Sarasin Alain; Magnaldo Thierry
Genetic correction of DNA repair-deficient/cancer-prone xeroderma pigmentosum group C keratinocytes.
Human gene therapy 2003;14(10):983-96.
2003: Ng Jessica M Y; Vermeulen Wim; van der Horst Gijsbertus T J; Bergink Steven; Sugasawa Kaoru; Vrieling Harry; Hoeijmakers Jan H J
A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein.
Genes & development 2003;17(13):1630-45.
2003: Mitchell James R; Hoeijmakers Jan H J; Niedernhofer Laura J
Divide and conquer: nucleotide excision repair battles cancer and ageing.
Current opinion in cell biology 2003;15(2):232-40.
2003: Janicijevic Ana; Sugasawa Kaoru; Shimizu Yuichiro; Hanaoka Fumio; Wijgers Nils; Djurica Miodrag; Hoeijmakers Jan H J; Wyman Claire
DNA bending by the human damage recognition complex XPC-HR23B.
DNA repair 2003;2(3):325-36.
2003: Hasty Paul; Campisi Judith; Hoeijmakers Jan; van Steeg Harry; Vijg Jan
Aging and genome maintenance: lessons from the mouse?
Science (New York, N.Y.) 2003;299(5611):1355-9.
2003: Baarends Willy M; Wassenaar Evelyne; Hoogerbrugge Jos W; van Cappellen Gert; Roest Henk P; Vreeburg Jan; Ooms Marja; Hoeijmakers Jan H J; Grootegoed J Anton
Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.
Molecular and cellular biology 2003;23(4):1151-62.
2003: de Waard Harm; de Wit Jan; Gorgels Theo G M F; van den Aardweg Gerard; Andressoo Jaan Olle; Vermeij Marcel; van Steeg Harry; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice.
DNA repair 2003;2(1):13-25.
2002: Jaspers Nicolaas G J; Raams Anja; Kelner Michael J; Ng Jessica M Y; Yamashita Yukiko M; Takeda Shiunichi; McMorris Trevor C; Hoeijmakers Jan H J
Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways.
DNA repair 2002;1(12):1027-38.
2002: Hoogstraten Deborah; Nigg Alex L; Heath Helen; Mullenders Leon H F; van Driel Roel; Hoeijmakers Jan H J; Vermeulen Wim; Houtsmuller Adriaan B
Rapid switching of TFIIH between RNA polymerase I and II transcription and DNA repair in vivo.
Molecular cell 2002;10(5):1163-74.
2002: Segers-Nolten G M J; Wyman C; Wijgers N; Vermeulen W; Lenferink A T M; Hoeijmakers J H J; Greve J; Otto C
Scanning confocal fluorescence microscopy for single molecule analysis of nucleotide excision repair complexes.
Nucleic acids research 2002;30(21):4720-7.
2002: Essers Jeroen; Hendriks Rudi W; Wesoly Joanna; Beerens Cecile E M T; Smit Bep; Hoeijmakers Jan H J; Wyman Claire; Dronkert Mies L G; Kanaar Roland
Analysis of mouse Rad54 expression and its implications for homologous recombination.
DNA repair 2002;1(10):779-93.
2002: Schul Wouter; Jans Judith; Rijksen Yvonne M A; Klemann Kyra H M; Eker Andre P M; de Wit Jan; Nikaido Osamu; Nakajima Satoshi; Yasui Akira; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Enhanced repair of cyclobutane pyrimidine dimers and improved UV resistance in photolyase transgenic mice.
The EMBO journal 2002;21(17):4719-29.
2002: Takao Masashi; Kanno Shin-ichiro; Shiromoto Tatsuya; Hasegawa Rei; Ide Hiroshi; Ikeda Shogo; Sarker Altaf H; Seki Shuji; Xing James Z; Le X Chris; Weinfeld Michael; Kobayashi Kumiko; Miyazaki Jun-ichi; Muijtjens Manja; Hoeijmakers Jan H J; van der Horst Gijsbertus; Yasui Akira;
Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols.
The EMBO journal 2002;21(13):3486-93.
2002: de Boer Jan; Andressoo Jaan Olle; de Wit Jan; Huijmans Jan; Beems Rudolph B; van Steeg Harry; Weeda Geert; van der Horst Gijsbertus T J; van Leeuwen Wibeke; Themmen Axel P N; Meradji Morteza; Hoeijmakers Jan H J
Premature aging in mice deficient in DNA repair and transcription.
Science (New York, N.Y.) 2002;296(5571):1276-9.
2002: Essers Jeroen; Houtsmuller Adriaan B; van Veelen Lieneke; Paulusma Coen; Nigg Alex L; Pastink Albert; Vermeulen Wim; Hoeijmakers Jan H J; Kanaar Roland
Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.
The EMBO journal 2002;21(8):2030-7.
2002: Yagita Kazuhiro; Tamanini Filippo; Yasuda Maya; Hoeijmakers Jan H J; van der Horst Gijsbertus T J; Okamura Hitoshi
Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein.
The EMBO journal 2002;21(6):1301-14.
2002: Verkaik Nicole S; Esveldt-van Lange Rebecca E E; van Heemst Diana; Brüggenwirth Hennie T; Hoeijmakers Jan H J; Zdzienicka Malgorzata Z; van Gent Dik C
Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells.
European journal of immunology 2002;32(3):701-9.
2002: van der Horst Gijsbertus T J; Meira Lisiane; Gorgels Theo G M F; de Wit Jan; Velasco-Miguel Susana; Richardson James A; Kamp Yvonne; Vreeswijk Maaike P G; Smit Bep; Bootsma Dirk; Hoeijmakers Jan H J; Friedberg Errol C
UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice.
DNA repair 2002;1(2):143-57.
2002: Ng Jessica M Y; Vrieling Harry; Sugasawa Kaoru; Ooms Marja P; Grootegoed J Anton; Vreeburg Jan T M; Visser Pim; Beems Rudolph B; Gorgels Theo G M F; Hanaoka Fumio; Hoeijmakers Jan H J; van der Horst Gijsbertus T J
Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B.
Molecular and cellular biology 2002;22(4):1233-45.
2002: Kamiuchi Shinya; Saijo Masafumi; Citterio Elisabetta; de Jager Martijn; Hoeijmakers Jan H J; Tanaka Kiyoji
Translocation of Cockayne syndrome group A protein to the nuclear matrix: possible relevance to transcription-coupled DNA repair.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):201-6.
2001: Niedernhofer L J; Essers J; Weeda G; Beverloo B; de Wit J; Muijtjens M; Odijk H; Hoeijmakers J H; Kanaar R
The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.
The EMBO journal 2001;20(22):6540-9.
2001: Murai M; Enokido Y; Inamura N; Yoshino M; Nakatsu Y; van der Horst G T; Hoeijmakers J H; Tanaka K; Hatanaka H
Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13379-84.
2001: Volker M; Moné M J; Karmakar P; van Hoffen A; Schul W; Vermeulen W; Hoeijmakers J H; van Driel R; van Zeeland A A; Mullenders L H
Sequential assembly of the nucleotide excision repair factors in vivo.
Molecular cell 2001;8(1):213-24.
2001: Boonstra A; van Oudenaren A; Baert M; van Steeg H; Leenen P J; van der Horst G T; Hoeijmakers J H; Savelkoul H F; Garssen J
Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice.
The Journal of investigative dermatology 2001;117(1):141-6.
2001: Hoeijmakers J H
Genome maintenance mechanisms for preventing cancer.
Nature 2001;411(6835):366-74.
2001: van Gent D C; Hoeijmakers J H; Kanaar R
Chromosomal stability and the DNA double-stranded break connection.
Nature reviews. Genetics 2001;2(3):196-206.
2001: Vermeulen W; Rademakers S; Jaspers N G; Appeldoorn E; Raams A; Klein B; Kleijer W J; Hansen L K; Hoeijmakers J H
A temperature-sensitive disorder in basal transcription and DNA repair in humans.
Nature genetics 2001;27(3):299-303.
2001: Hoeijmakers J H
From xeroderma pigmentosum to the biological clock contributions of Dirk Bootsma to human genetics.
Mutation research 2001;485(1):43-59.
2001: Verhoeven E E; Wyman C; Moolenaar G F; Hoeijmakers J H; Goosen N
Architecture of nucleotide excision repair complexes: DNA is wrapped by UvrB before and after damage recognition.
The EMBO journal 2001;20(3):601-11.
2001: Winkler G S; Sugasawa K; Eker A P; de Laat W L; Hoeijmakers J H
Novel functional interactions between nucleotide excision DNA repair proteins influencing the enzymatic activities of TFIIH, XPG, and ERCC1-XPF.
Biochemistry 2001;40(1):160-5.
2000: Seroz T; Winkler G S; Auriol J; Verhage R A; Vermeulen W; Smit B; Brouwer J; Eker A P; Weeda G; Egly J M; Hoeijmakers J H
Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases.
Nucleic acids research 2000;28(22):4506-13.
2000: Vermeulen W; Bergmann E; Auriol J; Rademakers S; Frit P; Appeldoorn E; Hoeijmakers J H; Egly J M
Sublimiting concentration of TFIIH transcription/DNA repair factor causes TTD-A trichothiodystrophy disorder.
Nature genetics 2000;26(3):307-13.
2000: Nakatsu Y; Asahina H; Citterio E; Rademakers S; Vermeulen W; Kamiuchi S; Yeo J P; Khaw M C; Saijo M; Kodo N; Matsuda T; Hoeijmakers J H; Tanaka K
XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription.
The Journal of biological chemistry 2000;275(45):34931-7.
2000: van der Laan R; Roest H P; Hoogerbrugge J W; Smit E M; Slater R; Baarends W M; Hoeijmakers J H; Grootegoed J A
Characterization of mRAD18Sc, a mouse homolog of the yeast postreplication repair gene RAD18.
Genomics 2000;69(1):86-94.
2000: Citterio E; Van Den Boom V; Schnitzler G; Kanaar R; Bonte E; Kingston R E; Hoeijmakers J H; Vermeulen W
ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor.
Molecular and cellular biology 2000;20(20):7643-53.
2000: Dronkert M L; de Wit J; Boeve M; Vasconcelos M L; van Steeg H; Tan T L; Hoeijmakers J H; Kanaar R
Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C.
Molecular and cellular biology 2000;20(13):4553-61.
2000: Garssen J; van Steeg H; de Gruijl F; de Boer J; van der Horst G T; van Kranen H; van Loveren H; van Dijk M; Fluitman A; Weeda G; Hoeijmakers J H
Transcription-coupled and global genome repair differentially influence UV-B-induced acute skin effects and systemic immunosuppression.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6199-205.
2000: Yagita K; Yamaguchi S; Tamanini F; van Der Horst G T; Hoeijmakers J H; Yasui A; Loros J J; Dunlap J C; Okamura H
Dimerization and nuclear entry of mPER proteins in mammalian cells.
Genes & development 2000;14(11):1353-63.
2000: Citterio E; Vermeulen W; Hoeijmakers J H
Transcriptional healing.
Cell 2000;101(5):447-50.
2000: Dronkert M L; Beverloo H B; Johnson R D; Hoeijmakers J H; Jasin M; Kanaar R
Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange.
Molecular and cellular biology 2000;20(9):3147-56.
2000: de Klein A; Muijtjens M; van Os R; Verhoeven Y; Smit B; Carr A M; Lehmann A R; Hoeijmakers J H
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.
Current biology : CB 2000;10(8):479-82.
2000: Essers J; van Steeg H; de Wit J; Swagemakers S M; Vermeij M; Hoeijmakers J H; Kanaar R
Homologous and non-homologous recombination differentially affect DNA damage repair in mice.
The EMBO journal 2000;19(7):1703-10.
2000: de Boer J; Hoeijmakers J H
Nucleotide excision repair and human syndromes.
Carcinogenesis 2000;21(3):453-60.
2000: Winkler G S; Araújo S J; Fiedler U; Vermeulen W; Coin F; Egly J M; Hoeijmakers J H; Wood R D; Timmers H T; Weeda G
TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.
The Journal of biological chemistry 2000;275(6):4258-66.
1999: Okamura H; Miyake S; Sumi Y; Yamaguchi S; Yasui A; Muijtjens M; Hoeijmakers J H; van der Horst G T
Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock.
Science (New York, N.Y.) 1999;286(5449):2531-4.
1999: Hiyama H; Yokoi M; Masutani C; Sugasawa K; Maekawa T; Tanaka K; Hoeijmakers J H; Hanaoka F
Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome.
The Journal of biological chemistry 1999;274(39):28019-25.
1999: de Boer J; van der Horst G T; Hoeijmakers J H
[Mutant mice as a model of human diseases of aging. Defective transcription and premature aging]
Tijdschrift voor gerontologie en geriatrie 1999;30(4):168-70.
1999: de Boer J; van Steeg H; Berg R J; Garssen J; de Wit J; van Oostrum C T; Beems R B; van der Horst G T; van Kreijl C F; de Gruijl F R; Bootsma D; Hoeijmakers J H; Weeda G
Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.
Cancer research 1999;59(14):3489-94.
1999: Glassner B J; Weeda G; Allan J M; Broekhof J L; Carls N H; Donker I; Engelward B P; Hampson R J; Hersmus R; Hickman M J; Roth R B; Warren H B; Wu M M; Hoeijmakers J H; Samson L D
DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents.
Mutagenesis 1999;14(3):339-47.
1999: Houtsmuller A B; Rademakers S; Nigg A L; Hoogstraten D; Hoeijmakers J H; Vermeulen W
Action of DNA repair endonuclease ERCC1/XPF in living cells.
Science (New York, N.Y.) 1999;284(5416):958-61.
1999: van der Horst G T; Muijtjens M; Kobayashi K; Takano R; Kanno S; Takao M; de Wit J; Verkerk A; Eker A P; van Leenen D; Buijs R; Bootsma D; Hoeijmakers J H; Yasui A
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.
Nature 1999;398(6728):627-30.
1999: de Laat W L; Jaspers N G; Hoeijmakers J H
Molecular mechanism of nucleotide excision repair.
Genes & development 1999;13(7):768-85.
1999: Tan T L; Essers J; Citterio E; Swagemakers S M; de Wit J; Benson F E; Hoeijmakers J H; Kanaar R
Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation.
Current biology : CB 1999;9(6):325-8.
1999: Baarends W M; Hoogerbrugge J W; Roest H P; Ooms M; Vreeburg J; Hoeijmakers J H; Grootegoed J A
Histone ubiquitination and chromatin remodeling in mouse spermatogenesis.
Developmental biology 1999;207(2):322-33.
1999: Bluyssen H A; Naus N C; van Os R I; Jaspers I; Hoeijmakers J H; de Klein A
Human and mouse homologs of the Schizosaccharomyces pombe rad17+ cell cycle checkpoint control gene.
Genomics 1999;55(2):219-28.
1998: Bluyssen H A; van Os R I; Naus N C; Jaspers I; Hoeijmakers J H; de Klein A
A human and mouse homolog of the Schizosaccharomyces pombe rad1+ cell cycle checkpoint control gene.
Genomics 1998;54(2):331-7.
1998: Grootegoed J A; Baarends W M; Roest H P; Hoeijmakers J H
Knockout mouse model and gametogenic failure.
Molecular and cellular endocrinology 1998;145(1-2):161-6.
1998: Swagemakers S M; Essers J; de Wit J; Hoeijmakers J H; Kanaar R
The human RAD54 recombinational DNA repair protein is a double-stranded DNA-dependent ATPase.
The Journal of biological chemistry 1998;273(43):28292-7.
1998: de Laat W L; Sijbers A M; Odijk H; Jaspers N G; Hoeijmakers J H
Mapping of interaction domains between human repair proteins ERCC1 and XPF.
Nucleic acids research 1998;26(18):4146-52.
1998: Sugasawa K; Ng J M; Masutani C; Iwai S; van der Spek P J; Eker A P; Hanaoka F; Bootsma D; Hoeijmakers J H
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair.
Molecular cell 1998;2(2):223-32.
1998: de Laat W L; Appeldoorn E; Sugasawa K; Weterings E; Jaspers N G; Hoeijmakers J H
DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair.
Genes & development 1998;12(16):2598-609.
1998: de Boer J; de Wit J; van Steeg H; Berg R J; Morreau H; Visser P; Lehmann A R; Duran M; Hoeijmakers J H; Weeda G
A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy.
Molecular cell 1998;1(7):981-90.
1998: Citterio E; Rademakers S; van der Horst G T; van Gool A J; Hoeijmakers J H; Vermeulen W
Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein.
The Journal of biological chemistry 1998;273(19):11844-51.
1998: de Laat W L; Appeldoorn E; Jaspers N G; Hoeijmakers J H
DNA structural elements required for ERCC1-XPF endonuclease activity.
The Journal of biological chemistry 1998;273(14):7835-42.
1998: de Boer J; Donker I; de Wit J; Hoeijmakers J H; Weeda G
Disruption of the mouse xeroderma pigmentosum group D DNA repair/basal transcription gene results in preimplantation lethality.
Cancer research 1998;58(1):89-94.
1998: Winkler G S; Vermeulen W; Coin F; Egly J M; Hoeijmakers J H; Weeda G
Affinity purification of human DNA repair/transcription factor TFIIH using epitope-tagged xeroderma pigmentosum B protein.
The Journal of biological chemistry 1998;273(2):1092-8.
1998: Weeda G; de Boer J; Donker I; de Wit J; Winkler S B; van der Horst G T; Vermeulen W; Bootsma D; Hoeijmakers J H
Molecular basis of DNA repair mechanisms and syndromes.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():147-55.
1997: Vichi P; Coin F; Renaud J P; Vermeulen W; Hoeijmakers J H; Moras D; Egly J M
Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.
The EMBO journal 1997;16(24):7444-56.
1997: Sugasawa K; Ng J M; Masutani C; Maekawa T; Uchida A; van der Spek P J; Eker A P; Rademakers S; Visser C; Aboussekhra A; Wood R D; Hanaoka F; Bootsma D; Hoeijmakers J H
Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity.
Molecular and cellular biology 1997;17(12):6924-31.
1997: Masutani C; Araki M; Sugasawa K; van der Spek P J; Yamada A; Uchida A; Maekawa T; Bootsma D; Hoeijmakers J H; Hanaoka F
Identification and characterization of XPC-binding domain of hHR23B.
Molecular and cellular biology 1997;17(12):6915-23.
1997: Engelward B P; Weeda G; Wyatt M D; Broekhof J L; de Wit J; Donker I; Allan J M; Gold B; Hoeijmakers J H; Samson L D
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):13087-92.
1997: van Gool A J; Citterio E; Rademakers S; van Os R; Vermeulen W; Constantinou A; Egly J M; Bootsma D; Hoeijmakers J H
The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.
The EMBO journal 1997;16(19):5955-65.
1997: van Gool A J; van der Horst G T; Citterio E; Hoeijmakers J H
Cockayne syndrome: defective repair of transcription?
The EMBO journal 1997;16(14):4155-62.
1997: Kanaar R; Hoeijmakers J H
Recombination and joining: different means to the same ends.
Genes and function 1997;1(3):165-74.
1997: Weeda G; Donker I; de Wit J; Morreau H; Janssens R; Vissers C J; Nigg A; van Steeg H; Bootsma D; Hoeijmakers J H
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence.
Current biology : CB 1997;7(6):427-39.
1997: Weeda G; Rossignol M; Fraser R A; Winkler G S; Vermeulen W; van 't Veer L J; Ma L; Hoeijmakers J H; Egly J M
The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor.
Nucleic acids research 1997;25(12):2274-83.
1997: van der Horst G T; van Steeg H; Berg R J; van Gool A J; de Wit J; Weeda G; Morreau H; Beems R B; van Kreijl C F; de Gruijl F R; Bootsma D; Hoeijmakers J H
Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition.
Cell 1997;89(3):425-35.
1997: Essers J; Hendriks R W; Swagemakers S M; Troelstra C; de Wit J; Bootsma D; Hoeijmakers J H; Kanaar R
Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.
Cell 1997;89(2):195-204.
1997: Marinoni J C; Roy R; Vermeulen W; Miniou P; Lutz Y; Weeda G; Seroz T; Gomez D M; Hoeijmakers J H; Egly J M
Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH.
The EMBO journal 1997;16(5):1093-102.
1997: Busch D B; van Vuuren H; de Wit J; Collins A; Zdzienicka M Z; Mitchell D L; Brookman K W; Stefanini M; Riboni R; Thompson L H; Albert R B; van Gool A J; Hoeijmakers J
Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4.
Mutation research 1997;383(2):91-106.
1997: Vermeulen W; de Boer J; Citterio E; van Gool A J; van der Horst G T; Jaspers N G; de Laat W L; Sijbers A M; van der Spek P J; Sugasawa K; Weeda G; Winkler G S; Bootsma D; Egly J M; Hoeijmakers J H
Mammalian nucleotide excision repair and syndromes.
Biochemical Society transactions 1997;25(1):309-15.
1997: Weeda G; Eveno E; Donker I; Vermeulen W; Chevallier-Lagente O; Taïeb A; Stary A; Hoeijmakers J H; Mezzina M; Sarasin A
A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy.
American journal of human genetics 1997;60(2):320-9.
1996: Moriwaki S; Stefanini M; Lehmann A R; Hoeijmakers J H; Robbins J H; Rapin I; Botta E; Tanganelli B; Vermeulen W; Broughton B C; Kraemer K H
DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells.
The Journal of investigative dermatology 1996;107(4):647-53.
1996: McKay M J; Troelstra C; van der Spek P; Kanaar R; Smit B; Hagemeijer A; Bootsma D; Hoeijmakers J H
Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse.
Genomics 1996;36(2):305-15.
1996: Sijbers A M; van der Spek P J; Odijk H; van den Berg J; van Duin M; Westerveld A; Jaspers N G; Bootsma D; Hoeijmakers J H
Mutational analysis of the human nucleotide excision repair gene ERCC1.
Nucleic acids research 1996;24(17):3370-80.
1996: Sijbers A M; de Laat W L; Ariza R R; Biggerstaff M; Wei Y F; Moggs J G; Carter K C; Shell B K; Evans E; de Jong M C; Rademakers S; de Rooij J; Jaspers N G; Hoeijmakers J H; Wood R D
Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease.
Cell 1996;86(5):811-22.
1996: Roest H P; van Klaveren J; de Wit J; van Gurp C G; Koken M H; Vermey M; van Roijen J H; Hoogerbrugge J W; Vreeburg J T; Baarends W M; Bootsma D; Grootegoed J A; Hoeijmakers J H
Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.
Cell 1996;86(5):799-810.
1996: Sugasawa K; Masutani C; Uchida A; Maekawa T; van der Spek P J; Bootsma D; Hoeijmakers J H; Hanaoka F
HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro.
Molecular and cellular biology 1996;16(9):4852-61.
1996: Kanaar R; Troelstra C; Swagemakers S M; Essers J; Smit B; Franssen J H; Pastink A; Bezzubova O Y; Buerstedde J M; Clever B; Heyer W D; Hoeijmakers J H
Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation.
Current biology : CB 1996;6(7):828-38.
1996: van der Spek P J; Eker A; Rademakers S; Visser C; Sugasawa K; Masutani C; Hanaoka F; Bootsma D; Hoeijmakers J H
XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes.
Nucleic acids research 1996;24(13):2551-9.
1996: Hwang J R; Moncollin V; Vermeulen W; Seroz T; van Vuuren H; Hoeijmakers J H; Egly J M
A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription.
The Journal of biological chemistry 1996;271(27):15898-904.
1996: Wang X W; Vermeulen W; Coursen J D; Gibson M; Lupold S E; Forrester K; Xu G; Elmore L; Yeh H; Hoeijmakers J H; Harris C C
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway.
Genes & development 1996;10(10):1219-32.
1996: Hoeijmakers J H; Egly J M; Vermeulen W
TFIIH: a key component in multiple DNA transactions.
Current opinion in genetics & development 1996;6(1):26-33.
1996: Verhage R A; van Gool A J; de Groot N; Hoeijmakers J H; van de Putte P; Brouwer J
Double mutants of Saccharomyces cerevisiae with alterations in global genome and transcription-coupled repair.
Molecular and cellular biology 1996;16(2):496-502.
1996: van der Spek P J; Visser C E; Hanaoka F; Smit B; Hagemeijer A; Bootsma D; Hoeijmakers J H
Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23.
Genomics 1996;31(1):20-7.
1996: Koken M H; Hoogerbrugge J W; Jasper-Dekker I; de Wit J; Willemsen R; Roest H P; Grootegoed J A; Hoeijmakers J H
Expression of the ubiquitin-conjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification.
Developmental biology 1996;173(1):119-32.
1995: Wang X W; Gibson M K; Vermeulen W; Yeh H; Forrester K; Stürzbecher H W; Hoeijmakers J H; Harris C C
Abrogation of p53-induced apoptosis by the hepatitis B virus X gene.
Cancer research 1995;55(24):6012-6.
1995: Ma L; Hoeijmakers J H; van der Eb A J
Mammalian nucleotide excision repair.
Biochimica et biophysica acta 1995;1242(2):137-63.
1995: Eveno E; Bourre F; Quilliet X; Chevallier-Lagente O; Roza L; Eker A P; Kleijer W J; Nikaido O; Stefanini M; Hoeijmakers J H
Different removal of ultraviolet photoproducts in genetically related xeroderma pigmentosum and trichothiodystrophy diseases.
Cancer research 1995;55(19):4325-32.
1995: Hendriksen P J; Hoogerbrugge J W; Themmen A P; Koken M H; Hoeijmakers J H; Oostra B A; van der Lende T; Grootegoed J A
Postmeiotic transcription of X and Y chromosomal genes during spermatogenesis in the mouse.
Developmental biology 1995;170(2):730-3.
1995: van Vuuren A J; Appeldoorn E; Odijk H; Humbert S; Moncollin V; Eker A P; Jaspers N G; Egly J M; Hoeijmakers J H
Partial characterization of the DNA repair protein complex, containing the ERCC1, ERCC4, ERCC11 and XPF correcting activities.
Mutation research 1995;337(1):25-39.
1995: Jaspers N G; Hoeijmakers J H
DNA repair. Nucleotide excision-repair in the test tube.
Current biology : CB 1995;5(7):700-2.
1995: Carreau M; Eveno E; Quilliet X; Chevalier-Lagente O; Benoit A; Tanganelli B; Stefanini M; Vermeulen W; Hoeijmakers J H; Sarasin A
Development of a new easy complementation assay for DNA repair deficient human syndromes using cloned repair genes.
Carcinogenesis 1995;16(5):1003-9.
1995: Broughton B C; Thompson A F; Harcourt S A; Vermeulen W; Hoeijmakers J H; Botta E; Stefanini M; King M D; Weber C A; Cole J
Molecular and cellular analysis of the DNA repair defect in a patient in xeroderma pigmentosum complementation group D who has the clinical features of xeroderma pigmentosum and Cockayne syndrome.
American journal of human genetics 1995;56(1):167-74.
1995: Bootsma D; Weeda G; Vermeulen W; van Vuuren H; Troelstra C; van der Spek P; Hoeijmakers J
Nucleotide excision repair syndromes: molecular basis and clinical symptoms.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1995;347(1319):75-81.
1994: Roy R; Adamczewski J P; Seroz T; Vermeulen W; Tassan J P; Schaeffer L; Nigg E A; Hoeijmakers J H; Egly J M
The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor.
Cell 1994;79(6):1093-101.
1994: van Gool A J; Verhage R; Swagemakers S M; van de Putte P; Brouwer J; Troelstra C; Bootsma D; Hoeijmakers J H
RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.
The EMBO journal 1994;13(22):5361-9.
1994: Muris D F; Bezzubova O; Buerstedde J M; Vreeken K; Balajee A S; Osgood C J; Troelstra C; Hoeijmakers J H; Ostermann K; Schmidt H
Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination.
Mutation research 1994;315(3):295-305.
1994: van der Spek P J; Smit E M; Beverloo H B; Sugasawa K; Masutani C; Hanaoka F; Hoeijmakers J H; Hagemeijer A
Chromosomal localization of three repair genes: the xeroderma pigmentosum group C gene and two human homologs of yeast RAD23.
Genomics 1994;23(3):651-8.
1994: Mezzina M; Eveno E; Chevallier-Lagente O; Benoit A; Carreau M; Vermeulen W; Hoeijmakers J H; Stefanini M; Lehmann A R; Weber C A
Correction by the ERCC2 gene of UV sensitivity and repair deficiency phenotype in a subset of trichothiodystrophy cells.
Carcinogenesis 1994;15(8):1493-8.
1994: Busch D; Greiner C; Rosenfeld K L; Ford R; de Wit J; Hoeijmakers J H; Thompson L H
Complementation group assignments of moderately UV-sensitive CHO mutants isolated by large-scale screening (FAECB).
Mutagenesis 1994;9(4):301-6.
1994: Ma L; Westbroek A; Jochemsen A G; Weeda G; Bosch A; Bootsma D; Hoeijmakers J H; van der Eb A J
Mutational analysis of ERCC3, which is involved in DNA repair and transcription initiation: identification of domains essential for the DNA repair function.
Molecular and cellular biology 1994;14(6):4126-34.
1994: Humbert S; van Vuuren H; Lutz Y; Hoeijmakers J H; Egly J M; Moncollin V
p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair.
The EMBO journal 1994;13(10):2393-8.
1994: Schaeffer L; Moncollin V; Roy R; Staub A; Mezzina M; Sarasin A; Weeda G; Hoeijmakers J H; Egly J M
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.
The EMBO journal 1994;13(10):2388-92.
1994: Bootsma D; Hoeijmakers J H
The molecular basis of nucleotide excision repair syndromes.
Mutation research 1994;307(1):15-23.
1994: Keeney S; Eker A P; Brody T; Vermeulen W; Bootsma D; Hoeijmakers J H; Linn S
Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4053-6.
1994: van Vuuren A J; Vermeulen W; Ma L; Weeda G; Appeldoorn E; Jaspers N G; van der Eb A J; Bootsma D; Hoeijmakers J H; Humbert S
Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).
The EMBO journal 1994;13(7):1645-53.
1994: Vermeulen W; Scott R J; Rodgers S; Müller H J; Cole J; Arlett C F; Kleijer W J; Bootsma D; Hoeijmakers J H; Weeda G
Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3.
American journal of human genetics 1994;54(2):191-200.
1994: Hoeijmakers J H
Human nucleotide excision repair syndromes: molecular clues to unexpected intricacies.
European journal of cancer (Oxford, England : 1990) 1994;30A(13):1912-21.
1993: Stefanini M; Vermeulen W; Weeda G; Giliani S; Nardo T; Mezzina M; Sarasin A; Harper J I; Arlett C F; Hoeijmakers J H
A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy.
American journal of human genetics 1993;53(4):817-21.
1993: Koken M H; Odijk H H; van Duin M; Fornerod M; Hoeijmakers J H
Augmentation of protein production by a combination of the T7 RNA polymerase system and ubiquitin fusion: overproduction of the human DNA repair protein, ERCC1, as a ubiquitin fusion protein in Escherichia coli.
Biochemical and biophysical research communications 1993;195(2):643-53.
1993: van Vuuren A J; Appeldoorn E; Odijk H; Yasui A; Jaspers N G; Bootsma D; Hoeijmakers J H
Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.
The EMBO journal 1993;12(9):3693-701.
1993: Vermeulen W; Jaeken J; Jaspers N G; Bootsma D; Hoeijmakers J H
Xeroderma pigmentosum complementation group G associated with Cockayne syndrome.
American journal of human genetics 1993;53(1):185-92.
1993: Hoeijmakers J H
Nucleotide excision repair. II: From yeast to mammals.
Trends in genetics : TIG 1993;9(6):211-7.
1993: Molinete M; Vermeulen W; Bürkle A; Ménissier-de Murcia J; Küpper J H; Hoeijmakers J H; de Murcia G
Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells.
The EMBO journal 1993;12(5):2109-17.
1993: Hoeijmakers J H
Nucleotide excision repair I: from E. coli to yeast.
Trends in genetics : TIG 1993;9(5):173-7.
1993: Weeda G; Hoeijmakers J H; Bootsma D
Genes controlling nucleotide excision repair in eukaryotic cells.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(4):249-58.
1993: Schaeffer L; Roy R; Humbert S; Moncollin V; Vermeulen W; Hoeijmakers J H; Chambon P; Egly J M
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor.
Science (New York, N.Y.) 1993;260(5104):58-63.
1993: Troelstra C; Hesen W; Bootsma D; Hoeijmakers J H
Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B.
Nucleic acids research 1993;21(3):419-26.
1992: Troelstra C; van Gool A; de Wit J; Vermeulen W; Bootsma D; Hoeijmakers J H
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes.
Cell 1992;71(6):939-53.
1992: Park E; Guzder S N; Koken M H; Jaspers-Dekker I; Weeda G; Hoeijmakers J H; Prakash S; Prakash L
RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11416-20.
1992: Koken M H; Vreeken C; Bol S A; Cheng N C; Jaspers-Dekker I; Hoeijmakers J H; Eeken J C; Weeda G; Pastink A
Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.
Nucleic acids research 1992;20(21):5541-8.
1992: Eker A P; Vermeulen W; Miura N; Tanaka K; Jaspers N G; Hoeijmakers J H; Bootsma D
Xeroderma pigmentosum group A correcting protein from calf thymus.
Mutation research 1992;274(3):211-24.
1992: Troelstra C; Landsvater R M; Wiegant J; van der Ploeg M; Viel G; Buys C H; Hoeijmakers J H
Localization of the nucleotide excision repair gene ERCC6 to human chromosome 10q11-q21.
Genomics 1992;12(4):745-9.
1992: Koken M H; Smit E M; Jaspers-Dekker I; Oostra B A; Hagemeijer A; Bootsma D; Hoeijmakers J H
Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.
Genomics 1992;12(3):447-53.
1992: Ma L; Weeda G; Jochemsen A G; Bootsma D; Hoeijmakers J H; van der Eb A J
Molecular and functional analysis of the XPBC/ERCC-3 promoter: transcription activity is dependent on the integrity of an Sp1-binding site.
Nucleic acids research 1992;20(2):217-24.
1992: Lehmann A R; Hoeijmakers J H; van Zeeland A A; Backendorf C M; Bridges B A; Collins A; Fuchs R P; Margison G P; Montesano R; Moustacchi E
Workshop on DNA repair.
Mutation research 1992;273(1):1-28.
1991: Hoeijmakers J H
How relevant is the Escherichia coli UvrABC model for excision repair in eukaryotes?
Journal of cell science 1991;100 (Pt 4)():687-91.
1991: Weeda G; Ma L; van Ham R C; Bootsma D; van der Eb A J; Hoeijmakers J H
Characterization of the mouse homolog of the XPBC/ERCC-3 gene implicated in xeroderma pigmentosum and Cockayne's syndrome.
Carcinogenesis 1991;12(12):2361-8.
1991: Weeda G; Ma L B; van Ham R C; van der Eb A J; Hoeijmakers J H
Structure and expression of the human XPBC/ERCC-3 gene involved in DNA repair disorders xeroderma pigmentosum and Cockayne's syndrome.
Nucleic acids research 1991;19(22):6301-8.
1991: Belt P B; van Oosterwijk M F; Odijk H; Hoeijmakers J H; Backendorf C
Induction of a mutant phenotype in human repair proficient cells after overexpression of a mutated human DNA repair gene.
Nucleic acids research 1991;19(20):5633-7.
1991: Koken M H; Reynolds P; Jaspers-Dekker I; Prakash L; Prakash S; Bootsma D; Hoeijmakers J H
Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):8865-9.
1991: Vermeulen W; Stefanini M; Giliani S; Hoeijmakers J H; Bootsma D
Xeroderma pigmentosum complementation group H falls into complementation group D.
Mutation research 1991;255(2):201-8.
1991: Belt P B; Jongmans W; de Wit J; Hoeijmakers J H; van de Putte P; Backendorf C
Efficient cDNA cloning by direct phenotypic correction of a mutant human cell line (HPRT-) using an Epstein-Barr virus-derived cDNA expression vector.
Nucleic acids research 1991;19(18):4861-6.
1991: Weeda G; Wiegant J; van der Ploeg M; Geurts van Kessel A H; van der Eb A J; Hoeijmakers J H
Localization of the xeroderma pigmentosum group B-correcting gene ERCC3 to human chromosome 2q21.
Genomics 1991;10(4):1035-40.
1991: Koken M; Reynolds P; Bootsma D; Hoeijmakers J; Prakash S; Prakash L
Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3832-6.
1991: Bootsma D; Hoeijmakers J H
The genetic basis of xeroderma pigmentosum.
Annales de génétique 1991;34(3-4):143-50.
1990: Troelstra C; Odijk H; de Wit J; Westerveld A; Thompson L H; Bootsma D; Hoeijmakers J H
Molecular cloning of the human DNA excision repair gene ERCC-6.
Molecular and cellular biology 1990;10(11):5806-13.
1990: Hoeijmakers J H; Eker A P; Wood R D; Robins P
Use of in vivo and in vitro assays for the characterization of mammalian excision repair and isolation of repair proteins.
Mutation research 1990;236(2-3):223-38.
1990: Weeda G; van Ham R C; Vermeulen W; Bootsma D; van der Eb A J; Hoeijmakers J H
A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome.
Cell 1990;62(4):777-91.
1990: Weeda G; van Ham R C; Masurel R; Westerveld A; Odijk H; de Wit J; Bootsma D; van der Eb A J; Hoeijmakers J H
Molecular cloning and biological characterization of the human excision repair gene ERCC-3.
Molecular and cellular biology 1990;10(6):2570-81.
1990: Reynolds P; Koken M H; Hoeijmakers J H; Prakash S; Prakash L
The rhp6+ gene of Schizosaccharomyces pombe: a structural and functional homolog of the RAD6 gene from the distantly related yeast Saccharomyces cerevisiae.
The EMBO journal 1990;9(5):1423-30.
1990: Gradwohl G; Ménissier de Murcia J M; Molinete M; Simonin F; Koken M; Hoeijmakers J H; de Murcia G
The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):2990-4.
1990: Roza L; Vermeulen W; Bergen Henegouwen J B; Eker A P; Jaspers N G; Lohman P H; Hoeijmakers J H
Effects of microinjected photoreactivating enzyme on thymine dimer removal and DNA repair synthesis in normal human and xeroderma pigmentosum fibroblasts.
Cancer research 1990;50(6):1905-10.
1989: van Duin M; van Den Tol J; Hoeijmakers J H; Bootsma D; Rupp I P; Reynolds P; Prakash L; Prakash S
Conserved pattern of antisense overlapping transcription in the homologous human ERCC-1 and yeast RAD10 DNA repair gene regions.
Molecular and cellular biology 1989;9(4):1794-8.
1989: van Duin M; Vredeveldt G; Mayne L V; Odijk H; Vermeulen W; Klein B; Weeda G; Hoeijmakers J H; Bootsma D; Westerveld A
The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I.
Mutation research 1989;217(2):83-92.
1989: Keijzer W; Mulder M P; Langeveld J C; Smit E M; Bos J L; Bootsma D; Hoeijmakers J H
Establishment and characterization of a melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.
Cancer research 1989;49(5):1229-35.
1988: van Duin M; van den Tol J; Warmerdam P; Odijk H; Meijer D; Westerveld A; Bootsma D; Hoeijmakers J H
Evolution and mutagenesis of the mammalian excision repair gene ERCC-1.
Nucleic acids research 1988;16(12):5305-22.
1988: van Duin M; Janssen J H; de Wit J; Hoeijmakers J H; Thompson L H; Bootsma D; Westerveld A
Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants.
Mutation research 1988;193(2):123-30.
1987: van Duin M; Koken M H; van den Tol J; ten Dijke P; Odijk H; Westerveld A; Bootsma D; Hoeijmakers J H
Genomic characterization of the human DNA excision repair gene ERCC-1.
Nucleic acids research 1987;15(22):9195-213.
1987: Hoeijmakers J H; Odijk H; Westerveld A
Differences between rodent and human cell lines in the amount of integrated DNA after transfection.
Experimental cell research 1987;169(1):111-9.
1987: Hoeijmakers J H
Characterization of genes and proteins involved in excision repair of human cells.
Journal of cell science. Supplement 1987;6():111-25.
1986: Zwetsloot J C; Barbeiro A P; Vermeulen W; Arthur H M; Hoeijmakers J H; Backendorf C
Microinjection of Escherichia coli UvrA, B, C and D proteins into fibroblasts of xeroderma pigmentosum complementation groups A and C does not result in restoration of UV-induced unscheduled DNA synthesis.
Mutation research 1986;166(1):89-98.
1986: van Duin M; de Wit J; Odijk H; Westerveld A; Yasui A; Koken M H; Hoeijmakers J H; Bootsma D
Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.
Cell 1986;44(6):913-23.
1985: Zwetsloot J C; Vermeulen W; Hoeijmakers J H; Yasui A; Eker A P; Bootsma D
Microinjected photoreactivating enzymes from Anacystis and Saccharomyces monomerize dimers in chromatin of human cells.
Mutation research 1985;146(1):71-7.
1984: Westerveld A; Hoeijmakers J H; van Duin M; de Wit J; Odijk H; Pastink A; Wood R D; Bootsma D
Molecular cloning of a human DNA repair gene.
Nature 1984;310(5976):425-9.

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