FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Dick Hoekstra

Research Profile

Anatomy

Chemicals & Drugs

Physiology

Concepts & Ideas

Cell Polarity

Living Beings

Rats

Co-author Network

Publications

TOP 3
Zia ur Rehman; Inge S Zuhorn; Dick Hoekstra
How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances.
Peter Meszaros; Stephen B Milne; David S Myers; Hjalmar Permentier; Annie van Dam; H Alex Brown; Dick Hoekstra; Pavlina T Ivanova; Karin Klappe; Jan Willem Kok
Long term myriocin treatment increases MRP1 transport activity.
Peter Meszaros; Oana Draghiciu; Dick Hoekstra; Ina Hummel; Karin Klappe; Jan Willem Kok
The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Dick Hoekstra (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Zia ur Rehman; Inge S Zuhorn; Dick Hoekstra
How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances.
Journal of controlled release : official journal of the Controlled Release Society 2013;166(1):46-56.
2013: Peter Meszaros; Stephen B Milne; David S Myers; Hjalmar Permentier; Annie van Dam; H Alex Brown; Dick Hoekstra; Pavlina T Ivanova; Karin Klappe; Jan Willem Kok
Long term myriocin treatment increases MRP1 transport activity.
The international journal of biochemistry & cell biology 2013;45(2):326-34.
2013: Peter Meszaros; Oana Draghiciu; Dick Hoekstra; Ina Hummel; Karin Klappe; Jan Willem Kok
The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption.
Biochimica et biophysica acta 2013;1828(2):340-51.
2013: Josephine M J Stoffels; Miriam E van Strien; Chao Zhao; Jenny C de Jonge; Charles ffrench-Constant; Robin J M Franklin; Dick Hoekstra; Dan Ma; Olaf Maier; Anita Nomden; Zuzana Sisková; Mirjana Stancic; Wia Baron
Fibronectin aggregation in multiple sclerosis lesions impairs remyelination.
Brain : a journal of neurology 2013;136(Pt 1):116-31.
2012: Peter Meszaros; Dick Hoekstra; Jan Willem Kok
The toolbox of vesicle sidedness determination.
Analytical biochemistry 2012;429(2):89-91.
2012: Zia ur Rehman; Dick Hoekstra; Jeroen Kuipers; Klaas A Sjollema; Inge S Zuhorn
Nonviral gene delivery vectors use syndecan-dependent transport mechanisms in filopodia to reach the cell surface.
ACS nano 2012;6(8):7521-32.
2012: Julia V Georgieva; Dick Hoekstra; Floris P J T Rutjes; Katica Stojanov; Jan C M van Hest; Carel A G M Weijers; René P Brinkhuis; Han Zuilhof; Inge S Zuhorn
Peptide-mediated blood-brain barrier transport of polymersomes.
Angewandte Chemie (International ed. in English) 2012;51(33):8339-42.
2012: Mirjana Stancic; Michel J Vos; Jenny C de Jonge; Hans-J Gabius; Dick Hoekstra; Anita Nomden; Arend H Sikkema; Davor Slijepcevic; Wia Baron
Galectin-4, a novel neuronal regulator of myelination.
Glia 2012;60(6):919-35.
2012: Katica Stojanov; Aren van Waarde; Erik F J de Vries; Rudi A J O Dierckx; Dick Hoekstra; Inge S Zuhorn
[18F]FDG labeling of neural stem cells for in vivo cell tracking with positron emission tomography: inhibition of tracer release by phloretin.
Molecular imaging 2012;11(1):1-12.
2011: Zia ur Rehman; Dick Hoekstra; Inge S Zuhorn
Protein kinase A inhibition modulates the intracellular routing of gene delivery vehicles in HeLa cells, leading to productive transfection.
Journal of controlled release : official journal of the Controlled Release Society 2011;156(1):76-84.
2011: Peter Meszaros; Dick Hoekstra; Ina Hummel; Karin Klappe; Jan Willem Kok
Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts.
The Biochemical journal 2011;437(3):483-91.
2011: Agata M Szperl; Magdalena R Golachowska; Marcel Bruinenberg; Rytis Prekeris; Andy-Mark W H Thunnissen; Arend Karrenbeld; Gerard Dijkstra; Dick Hoekstra; David Mercer; Janusz Ksiazyk; Cisca Wijmenga; Martin C Wapenaar; Edmond H H M Rings; Sven C D van IJzendoorn
Functional characterization of mutations in the myosin Vb gene associated with microvillus inclusion disease.
Journal of pediatric gastroenterology and nutrition 2011;52(3):307-13.
2011: Julia V Georgieva; Dharamdajal Kalicharan; Pierre-Olivier Couraud; Ignacio Romero; Babette Weksler; Dick Hoekstra; Inge S Zuhorn
Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(2):318-25.
2010: Marcelo de Jesus; Carmen Veríssima Ferreira; Eneida de Paula; Dick Hoekstra; Inge S Zuhorn
Design of solid lipid nanoparticles for gene delivery into prostate cancer.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e89-90.
2010: Wia Baron; Dick Hoekstra
On the biogenesis of myelin membranes: sorting, trafficking and cell polarity.
FEBS letters 2010;584(9):1760-70.
2009: Zuzana Sisková; V Wee Yong; Anita Nomden; Miriam van Strien; Dick Hoekstra; Wia Baron
Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity.
Molecular and cellular neurosciences 2009;42(3):234-42.
2009: Karin Klappe; Ina Hummel; Dick Hoekstra; Jan Willem Kok
Lipid dependence of ABC transporter localization and function.
Chemistry and physics of lipids 2009;161(2):57-64.
2009: Kacper A Wojtal; Mandy Diskar; Friedrich W Herberg; Dick Hoekstra; Sven C D van IJzendoorn
Regulatory subunit I-controlled protein kinase A activity is required for apical bile canalicular lumen development in hepatocytes.
The Journal of biological chemistry 2009;284(31):20773-80.
2009: Olaf Maier; Jenny De Jonge; Anita Nomden; Dick Hoekstra; Wia Baron
Lovastatin induces the formation of abnormal myelin-like membrane sheets in primary oligodendrocytes.
Glia 2009;57(4):402-13.
2008: Kousei Ito; Dick Hoekstra; Sven C D van IJzendoorn
Cholesterol but not association with detergent resistant membranes is necessary for the transport function of MRP2/ABCC2.
FEBS letters 2008;582(30):4153-7.
2008: Olaf Maier; Dick Hoekstra; Wia Baron
Polarity development in oligodendrocytes: sorting and trafficking of myelin components.
Journal of molecular neuroscience : MN 2008;35(1):35-53.
2008: Delphine Théard; Marcel A Raspe; Dharamdajal Kalicharan; Dick Hoekstra; Sven C D van IJzendoorn
Formation of E-cadherin/beta-catenin-based adherens junctions in hepatocytes requires serine-10 in p27(Kip1).
Molecular biology of the cell 2008;19(4):1605-13.
2008: Bert Klunder; Wia Baron; Cobi Schrage; Jenny de Jonge; Hans De Vries; Dick Hoekstra
Sorting signals and regulation of cognate basolateral trafficking in myelin biogenesis.
Journal of neuroscience research 2008;86(5):1007-16.
2008: Kacper A Wojtal; Dick Hoekstra; Sven C D van IJzendoorn
cAMP-dependent protein kinase A and the dynamics of epithelial cell surface domains: moving membranes to keep in shape.
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(2):146-55.
2008: Heike Bakowsky; Thomas Richter; Carsten Kneuer; Dick Hoekstra; Ulrich Rothe; Gerd Bendas; Carsten Ehrhardt; Udo Bakowsky
Adhesion characteristics and stability assessment of lectin-modified liposomes for site-specific drug delivery.
Biochimica et biophysica acta 2008;1778(1):242-9.
2007: Kacper A Wojtal; Dick Hoekstra; Sven C D van IJzendoorn
Anchoring of protein kinase A-regulatory subunit IIalpha to subapically positioned centrosomes mediates apical bile canalicular lumen development in response to oncostatin M but not cAMP.
Molecular biology of the cell 2007;18(7):2745-54.
2007: Delphine Théard; Magdalena Steiner; Dharamdajal Kalicharan; Dick Hoekstra; Sven C D van IJzendoorn
Cell polarity development and protein trafficking in hepatocytes lacking E-cadherin/beta-catenin-based adherens junctions.
Molecular biology of the cell 2007;18(6):2313-21.
2007: Olaf Maier; Wia Baron; Dick Hoekstra
Reduced raft-association of NF155 in active MS-lesions is accompanied by the disruption of the paranodal junction.
Glia 2007;55(8):885-95.
2007: Inge S Zuhorn; Dharamdajal Kalicharan; George T Robillard; Dick Hoekstra
Adhesion receptors mediate efficient non-viral gene delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(5):946-53.
2007: Inge S Zuhorn; Jan B F N Engberts; Dick Hoekstra
Gene delivery by cationic lipid vectors: overcoming cellular barriers.
European biophysics journal : EBJ 2007;36(4-5):349-62.
2007: Dick Hoekstra; J Rejman; Luc Wasungu; F Shi; Inge S Zuhorn
Gene delivery by cationic lipids: in and out of an endosome.
Biochemical Society transactions 2007;35(Pt 1):68-71.
2007: Fuxin Shi; Natasha V Gounko; Xiaoqin Wang; Eric Ronken; Dick Hoekstra
In situ entry of oligonucleotides into brain cells can occur through a nucleic acid channel.
Oligonucleotides 2007;17(1):122-33.
2006: Luc Wasungu; Dick Hoekstra
Cationic lipids, lipoplexes and intracellular delivery of genes.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):255-64.
2006: Ellen Gielen; Wia Baron; Martin VandeVen; Paul Steels; Dick Hoekstra; Marcel Ameloot
Rafts in oligodendrocytes: evidence and structure-function relationship.
Glia 2006;54(6):499-512.
2006: Zuzana Sisková; Wia Baron; Hans De Vries; Dick Hoekstra
Fibronectin impedes "myelin" sheet-directed flow in oligodendrocytes: a role for a beta 1 integrin-mediated PKC signaling pathway in vesicular trafficking.
Molecular and cellular neurosciences 2006;33(2):150-9.
2006: Luc Wasungu; Marc Stuart; Marco Scarzello; Jan B F N Engberts; Dick Hoekstra
Lipoplexes formed from sugar-based gemini surfactants undergo a lamellar-to-micellar phase transition at acidic pH. Evidence for a non-inverted membrane-destabilizing hexagonal phase of lipoplexes.
Biochimica et biophysica acta 2006;1758(10):1677-84.
2006: Carsten Kneuer; Carsten Ehrhardt; Heike Bakowsky; M N V Ravi Kumar; Volker Oberle; Claus-Michael Lehr; Dick Hoekstra; Udo Bakowsky
The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: a comparative study.
Journal of nanoscience and nanotechnology 2006;6(9-10):2776-82.
2006: Luc Wasungu; Marco Scarzello; Gooitzen van Dam; Grietje Molema; Anno Wagenaar; Jan B F N Engberts; Dick Hoekstra
Transfection mediated by pH-sensitive sugar-based gemini surfactants; potential for in vivo gene therapy applications.
Journal of molecular medicine (Berlin, Germany) 2006;84(9):774-84.
2006: Kacper A Wojtal; Erik de Vries; Dick Hoekstra; Sven C D van IJzendoorn
Efficient trafficking of MDR1/P-glycoprotein to apical canalicular plasma membranes in HepG2 cells requires PKA-RIIalpha anchoring and glucosylceramide.
Molecular biology of the cell 2006;17(8):3638-50.
2006: Hilde Herrema; Dominika Czajkowska; Delphine Théard; Johanna M van der Wouden; Dharamdajal Kalicharan; Behnam Zolghadr; Dick Hoekstra; Sven C D van IJzendoorn
Rho kinase, myosin-II, and p42/44 MAPK control extracellular matrix-mediated apical bile canalicular lumen morphogenesis in HepG2 cells.
Molecular biology of the cell 2006;17(7):3291-303.
2006: Olaf Maier; Tiemen van der Heide; Richard Johnson; Hans De Vries; Wia Baron; Dick Hoekstra
The function of neurofascin155 in oligodendrocytes is regulated by metalloprotease-mediated cleavage and ectodomain shedding.
Experimental cell research 2006;312(4):500-11.
2005: Donatienne Tyteca; Sven C D van IJzendoorn; Dick Hoekstra
Calmodulin modulates hepatic membrane polarity by protein kinase C-sensitive steps in the basolateral endocytic pathway.
Experimental cell research 2005;310(2):293-302.
2005: Marco Scarzello; Jarmila Smisterová; Anno Wagenaar; Marc Stuart; Dick Hoekstra; Jan B F N Engberts; Ron Hulst
Sunfish cationic amphiphiles: toward an adaptative lipoplex morphology.
Journal of the American Chemical Society 2005;127(29):10420-9.
2005: Inge S Zuhorn; Udo Bakowsky; Evgeny Polushkin; Willy H Visser; Marc Stuart; Jan B F N Engberts; Dick Hoekstra
Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(5):801-10.
2005: Olaf Maier; Tiemen van der Heide; Anne-Marie Van Dam; Wia Baron; Hans De Vries; Dick Hoekstra
Alteration of the extracellular matrix interferes with raft association of neurofascin in oligodendrocytes. Potential significance for multiple sclerosis?
Molecular and cellular neurosciences 2005;28(2):390-401.
2005: M Haas; Sandrine A L Audouy; I Muizebelt; Jarmila Smisterová; Jan B F N Engberts; Dick Hoekstra; G Storm; Ron Hulst
In-vivo delivery of DNA and protein using conceptually new cationic, sunfish', amphiphiles.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):401.
2004: aude de gassart; Charles Géminard; Dick Hoekstra; Michel Vidal
Exosome secretion: the art of reutilizing nonrecycled proteins?
Traffic (Copenhagen, Denmark) 2004;5(11):896-903.
2004: Sven C D van IJzendoorn; Delphine Théard; Johanna M van der Wouden; Willy Visser; Kacper A Wojtal; Dick Hoekstra
Oncostatin M-stimulated apical plasma membrane biogenesis requires p27(Kip1)-regulated cell cycle dynamics.
Molecular biology of the cell 2004;15(9):4105-14.
2004: Sven C D van IJzendoorn; Johanna M van der Wouden; Gerhard Liebisch; Gerd Schmitz; Dick Hoekstra
Polarized membrane traffic and cell polarity development is dependent on dihydroceramide synthase-regulated sphinganine turnover.
Molecular biology of the cell 2004;15(9):4115-24.
2004: Fuxin Shi; Dick Hoekstra
Effective intracellular delivery of oligonucleotides in order to make sense of antisense.
Journal of controlled release : official journal of the Controlled Release Society 2004;97(2):189-209.
2004: Dick Hoekstra; Donatienne Tyteca; Sven C D van IJzendoorn
The subapical compartment: a traffic center in membrane polarity development.
Journal of cell science 2004;117(Pt 11):2183-92.
2004: Volker Oberle; Gary de Jong; Jan I Drayer; Dick Hoekstra
Efficient transfer of chromosome-based DNA constructs into mammalian cells.
Biochimica et biophysica acta 2004;1676(3):223-30.
2004: Joanna Rejman; Anno Wagenaar; Jan B F N Engberts; Dick Hoekstra
Characterization and transfection properties of lipoplexes stabilized with novel exchangeable polyethylene glycol-lipid conjugates.
Biochimica et biophysica acta 2004;1660(1-2):41-52.
2004: Joanna Rejman; Volker Oberle; Inge S Zuhorn; Dick Hoekstra
Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis.
The Biochemical journal 2004;377(Pt 1):159-69.
2003: Fuxin Shi; Willy H Visser; Natasja M J de Jong; Robert S B Liem; Eric Ronken; Dick Hoekstra
Antisense oligonucleotides reach mRNA targets via the RNA matrix: downregulation of the 5-HT1A receptor.
Experimental cell research 2003;291(2):313-25.
2003: Dick Hoekstra; Olaf Maier; Johanna M van der Wouden; Tounsia Aït Slimane; Sven C D van IJzendoorn
Membrane dynamics and cell polarity: the role of sphingolipids.
Journal of lipid research 2003;44(5):869-77.
2003: Tounsia Aït Slimane; Germain Trugnan; Sven C D van IJzendoorn; Dick Hoekstra
Raft-mediated trafficking of apical resident proteins occurs in both direct and transcytotic pathways in polarized hepatic cells: role of distinct lipid microdomains.
Molecular biology of the cell 2003;14(2):611-24.
2003: Olaf Maier; Dick Hoekstra
Trans-Golgi network and subapical compartment of HepG2 cells display different properties in sorting and exiting of sphingolipids.
The Journal of biological chemistry 2003;278(1):164-73.
2003: Volker Oberle; Udo Bakowsky; Dick Hoekstra
Lipoplex assembly visualized by atomic force microscopy.
Methods in enzymology 2003;373():281-97.
2003: Sven C D van IJzendoorn; Keith E Mostov; Dick Hoekstra
Role of rab proteins in epithelial membrane traffic.
International review of cytology 2003;232():59-88.
2003: Johanna M van der Wouden; Olaf Maier; Sven C D van IJzendoorn; Dick Hoekstra
Membrane dynamics and the regulation of epithelial cell polarity.
International review of cytology 2003;226():127-64.
2003: Dick Hoekstra; Sven C D van IJzendoorn
In search of lipid translocases and their biological functions.
Developmental cell 2003;4(1):8-9.
2002: Johanna M van der Wouden; Sven C D van IJzendoorn; Dick Hoekstra
Oncostatin M regulates membrane traffic and stimulates bile canalicular membrane biogenesis in HepG2 cells.
The EMBO journal 2002;21(23):6409-18.
2002: Sandrine A L Audouy; Lou F M H De Leij; Dick Hoekstra; Grietje Molema
In vivo characteristics of cationic liposomes as delivery vectors for gene therapy.
Pharmaceutical research 2002;19(11):1599-605.
2002: Nicoletta Kahya; Douwe A Wiersma; Bert Poolman; Dick Hoekstra
Spatial organization of bacteriorhodopsin in model membranes. Light-induced mobility changes.
The Journal of biological chemistry 2002;277(42):39304-11.
2002: Tounsia Aït Slimane; Dick Hoekstra
Sphingolipid trafficking and protein sorting in epithelial cells.
FEBS letters 2002;529(1):54-9.
2002: Inge S Zuhorn; Dick Hoekstra
On the mechanism of cationic amphiphile-mediated transfection. To fuse or not to fuse: is that the question?
The Journal of membrane biology 2002;189(3):167-79.
2002: Inge S Zuhorn; Volker Oberle; Willy H Visser; Jan B F N Engberts; Udo Bakowsky; Evgeny Polushkin; Dick Hoekstra
Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency.
Biophysical journal 2002;83(4):2096-108.
2002: Fuxin Shi; Luc Wasungu; Anita Nomden; Marc Stuart; Evgeny Polushkin; Jan B F N Engberts; Dick Hoekstra
Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid-mediated delivery of oligonucleotides; role of lipid exchangeability and non-lamellar transitions.
The Biochemical journal 2002;366(Pt 1):333-41.
2002: Eve-Isabelle Pécheur; Isabelle Martin; Olaf Maier; Udo Bakowsky; Jean-Marie Ruysschaert; Dick Hoekstra
Phospholipid species act as modulators in p97/p47-mediated fusion of Golgi membranes.
Biochemistry 2002;41(31):9813-23.
2002: Nicole M Kühl; Jacques De Keyser; Hans De Vries; Dick Hoekstra
Insulin-like growth factor binding proteins-1 and -2 differentially inhibit rat oligodendrocyte precursor cell survival and differentiation in vitro.
Journal of neuroscience research 2002;69(2):207-16.
2002: Olaf Maier; Volker Oberle; Dick Hoekstra
Fluorescent lipid probes: some properties and applications (a review).
Chemistry and physics of lipids 2002;116(1-2):3-18.
2002: Inge S Zuhorn; Ruby Kalicharan; Dick Hoekstra
Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis.
The Journal of biological chemistry 2002;277(20):18021-8.
2002: Inge S Zuhorn; Willy H Visser; Udo Bakowsky; Jan B F N Engberts; Dick Hoekstra
Interference of serum with lipoplex-cell interaction: modulation of intracellular processing.
Biochimica et biophysica acta 2002;1560(1-2):25-36.
2002: Dick Hoekstra; Isabelle Martin; Nicoletta Kahya; Jean-Marie Ruysschaert; Eve-Isabelle Pécheur
On the mechanism of protein-induced membrane fusion: from model to biological membranes.
Cellular & molecular biology letters 2002;7(2):231-2.
2002: Eve-Isabelle Pécheur; Dick Hoekstra
Peptide-induced fusion of liposomes.
Methods in molecular biology (Clifton, N.J.) 2002;199():31-48.
2001: Jarmila Smisterová; Anno Wagenaar; Marc Stuart; Evgeny Polushkin; Gerrit ten Brinke; Ron Hulst; Jan B F N Engberts; Dick Hoekstra
Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery.
The Journal of biological chemistry 2001;276(50):47615-22.
2001: Nicoletta Kahya; Eve-Isabelle Pécheur; WP de Boeij; Douwe A Wiersma; Dick Hoekstra
Reconstitution of membrane proteins into giant unilamellar vesicles via peptide-induced fusion.
Biophysical journal 2001;81(3):1464-74.
2001: Fuxin Shi; A Nomden; Volker Oberle; Jan B F N Engberts; Dick Hoekstra
Efficient cationic lipid-mediated delivery of antisense oligonucleotides into eukaryotic cells: down-regulation of the corticotropin-releasing factor receptor.
Nucleic acids research 2001;29(10):2079-87.
2001: Sandrine A L Audouy; Dick Hoekstra
Cationic lipid-mediated transfection in vitro and in vivo (review).
Molecular membrane biology 2001;18(2):129-43.
2001: Olaf Maier; T Aït Slimane; Dick Hoekstra
Membrane domains and polarized trafficking of sphingolipids.
Seminars in cell & developmental biology 2001;12(2):149-61.
2000: Eve-Isabelle Pécheur; Olaf Maier; Dick Hoekstra
On the mechanism of intracellular membrane fusion: in search of the genuine fusion factor.
Bioscience reports 2000;20(6):613-31.
2000: Sandrine A L Audouy; Grietje Molema; Lou de Leij; Dick Hoekstra
Serum as a modulator of lipoplex-mediated gene transfection: dependence of amphiphile, cell type and complex stability.
The journal of gene medicine 2000;2(6):465-76.
2000: Volker Oberle; Udo Bakowsky; Inge S Zuhorn; Dick Hoekstra
Lipoplex formation under equilibrium conditions reveals a three-step mechanism.
Biophysical journal 2000;79(3):1447-54.
2000: Dick Hoekstra; Sven C D van IJzendoorn
Lipid trafficking and sorting: how cholesterol is filling gaps.
Current opinion in cell biology 2000;12(4):496-502.
2000: Sven C D van IJzendoorn; Olaf Maier; Johanna M van der Wouden; Dick Hoekstra
The subapical compartment and its role in intracellular trafficking and cell polarity.
Journal of cellular physiology 2000;184(2):151-60.
2000: Hans De Vries; Dick Hoekstra
On the biogenesis of the myelin sheath: cognate polarized trafficking pathways in oligodendrocytes.
Glycoconjugate journal 2000;17(3 -4):181-90.
2000: W Baron; B Metz; R Bansal; Dick Hoekstra; Hans De Vries
PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathways.
Molecular and cellular neurosciences 2000;15(3):314-29.
2000: Sven C D van IJzendoorn; Dick Hoekstra
Polarized sphingolipid transport from the subapical compartment changes during cell polarity development.
Molecular biology of the cell 2000;11(3):1093-101.
2000: Eve-Isabelle Pécheur; Isabelle Martin; A Bienvenüe; Jean-Marie Ruysschaert; Dick Hoekstra
Protein-induced fusion can be modulated by target membrane lipids through a structural switch at the level of the fusion peptide.
The Journal of biological chemistry 2000;275(6):3936-42.
2000: W Baron; Jørgen de Jonge; Hans De Vries; Dick Hoekstra
Perturbation of myelination by activation of distinct signaling pathways: an in vitro study in a myelinating culture derived from fetal rat brain.
Journal of neuroscience research 2000;59(1):74-85.
1999: Robert Jan Veldman; Hannie Sietsma; Karin Klappe; Dick Hoekstra; Jan Willem Kok
Inhibition of P-glycoprotein activity and chemosensitization of multidrug-resistant ovarian carcinoma 2780AD cells by hexanoylglucosylceramide.
Biochemical and biophysical research communications 1999;266(2):492-6.
1999: W Baron; E J de Vries; Hans De Vries; Dick Hoekstra
Protein kinase C prevents oligodendrocyte differentiation: modulation of actin cytoskeleton and cognate polarized membrane traffic.
Journal of neurobiology 1999;41(3):385-98.
1999: Sven C D van IJzendoorn; Dick Hoekstra
Polarized sphingolipid transport from the subapical compartment: evidence for distinct sphingolipid domains.
Molecular biology of the cell 1999;10(10):3449-61.
1999: Dick Hoekstra; MM Zegers; Sven C D van IJzendoorn
Membrane flow, lipid sorting and cell polarity in HepG2 cells: role of a subapical compartment.
Biochemical Society transactions 1999;27(4):422-8.
1999: Eve-Isabelle Pécheur; J Sainte-Marie; A Bienvenüe; Dick Hoekstra
Lipid headgroup spacing and peptide penetration, but not peptide oligomerization, modulate peptide-induced fusion.
Biochemistry 1999;38(1):364-73.
1999: EB van Leeuwen; Anneke Y van der Veen; Dick Hoekstra; Jan B F N Engberts; M R Halie; Jan van der Meer; Marcel H J Ruiters
Transfection of small numbers of human endothelial cells by electroporation and synthetic amphiphiles.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1999;17(1):9-14.
1999: Eve-Isabelle Pécheur; J Sainte-Marie; A Bienven e; Dick Hoekstra
Peptides and membrane fusion: towards an understanding of the molecular mechanism of protein-induced fusion.
The Journal of membrane biology 1999;167(1):1-17.
1998: MM Zegers; Dick Hoekstra
Mechanisms and functional features of polarized membrane traffic in epithelial and hepatic cells.
The Biochemical journal 1998;336 ( Pt 2)():257-69.
1998: T Babia; Robert Jan Veldman; Dick Hoekstra; Jan Willem Kok
Modulation of carcinoembryonic antigen release by glucosylceramide--implications for HT29 cell differentiation.
European journal of biochemistry / FEBS 1998;258(1):233-42.
1998: Sven C D van IJzendoorn; Dick Hoekstra
(Glyco)sphingolipids are sorted in sub-apical compartments in HepG2 cells: a role for non-Golgi-related intracellular sites in the polarized distribution of (glyco)sphingolipids.
The Journal of cell biology 1998;142(3):683-96.
1998: Jan Willem Kok; T Babia; Karin Klappe; Gustavo Egea; Dick Hoekstra
Ceramide transport from endoplasmic reticulum to Golgi apparatus is not vesicle-mediated.
The Biochemical journal 1998;333 ( Pt 3)():779-86.
1998: Jan Willem Kok; T Babia; Catalin M Filipeanu; Adriaan Nelemans; Gustavo Egea; Dick Hoekstra
PDMP blocks brefeldin A-induced retrograde membrane transport from golgi to ER: evidence for involvement of calcium homeostasis and dissociation from sphingolipid metabolism.
The Journal of cell biology 1998;142(1):25-38.
1998: MM Zegers; K J Zaal; Sven C D van IJzendoorn; Karin Klappe; Dick Hoekstra
Actin filaments and microtubules are involved in different membrane traffic pathways that transport sphingolipids to the apical surface of polarized HepG2 cells.
Molecular biology of the cell 1998;9(7):1939-49.
1998: Robert Jan Veldman; Karin Klappe; Dick Hoekstra; Jan Willem Kok
Interferon-gamma-induced differentiation and apoptosis of HT29 cells: dissociation of (glucosyl)ceramide signaling.
Biochemical and biophysical research communications 1998;247(3):802-8.
1998: Robert Jan Veldman; Karin Klappe; Dick Hoekstra; Jan Willem Kok
Metabolism and apoptotic properties of elevated ceramide in HT29rev cells.
The Biochemical journal 1998;331 ( Pt 2)():563-9.
1998: MM Zegers; K J Zaal; Dick Hoekstra
Functional involvement of proteins, interacting with sphingolipids, in sphingolipid transport to the canalicular membrane in the human hepatocytic cell line, HepG2?
Hepatology (Baltimore, Md.) 1998;27(4):1089-97.
1998: Hans De Vries; C Schrage; Dick Hoekstra
An apical-type trafficking pathway is present in cultured oligodendrocytes but the sphingolipid-enriched myelin membrane is the target of a basolateral-type pathway.
Molecular biology of the cell 1998;9(3):599-609.
1998: E I Pecheur; Isabelle Martin; Jean-Marie Ruysschaert; A Bienvenue; Dick Hoekstra
Membrane fusion induced by 11-mer anionic and cationic peptides: a structure-function study.
Biochemistry 1998;37(8):2361-71.
1998: W Baron; Jørgen de Jonge; Hans De Vries; Dick Hoekstra
Regulation of oligodendrocyte differentiation: protein kinase C activation prevents differentiation of O2A progenitor cells toward oligodendrocytes.
Glia 1998;22(2):121-9.
1998: M E van der Haar; H W Visser; Hans De Vries; Dick Hoekstra
Transport of proteolipid protein to the plasma membrane does not depend on glycosphingolipid cotransport in oligodendrocyte cultures.
Journal of neuroscience research 1998;51(3):371-81.
1997: MM Zegers; Jan Willem Kok; Dick Hoekstra
Use of photoactivatable sphingolipid analogues to monitor lipid transport in mammalian cells.
The Biochemical journal 1997;328 ( Pt 2)():489-98.
1997: Michel Vidal; Paul Mangeat; Dick Hoekstra
Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation.
Journal of cell science 1997;110 ( Pt 16)():1867-77.
1997: MM Zegers; Dick Hoekstra
Sphingolipid transport to the apical plasma membrane domain in human hepatoma cells is controlled by PKC and PKA activity: a correlation with cell polarity in HepG2 cells.
The Journal of cell biology 1997;138(2):307-21.
1997: E G J M Arts; J G Wijchman; S Jager; Dick Hoekstra
Protein involvement in the fusion between the equatorial segment of acrosome-reacted human spermatozoa and liposomes.
The Biochemical journal 1997;325 ( Pt 1)():191-8.
1997: Sven C D van IJzendoorn; MM Zegers; Jan Willem Kok; Dick Hoekstra
Segregation of glucosylceramide and sphingomyelin occurs in the apical to basolateral transcytotic route in HepG2 cells.
The Journal of cell biology 1997;137(2):347-57.
1997: Eve-Isabelle Pécheur; Dick Hoekstra; J Sainte-Marie; Laurence Maurin; A Bienvenüe; J R Philippot
Membrane anchorage brings about fusogenic properties in a short synthetic peptide.
Biochemistry 1997;36(13):3773-81.
1997: Hans De Vries; Jørgen de Jonge; C Schrage; M E van der Haar; Dick Hoekstra
Differential and cell development-dependent localization of myelin mRNAs in oligodendrocytes.
Journal of neuroscience research 1997;47(5):479-88.
1997: I van der Woude; Anno Wagenaar; A A Meekel; M B ter Beest; Marcel H J Ruiters; Jan B F N Engberts; Dick Hoekstra
Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1160-5.
1995: Jan B F N Engberts; Dick Hoekstra
Vesicle-forming synthetic amphiphiles.
Biochimica et biophysica acta 1995;1241(3):323-40.
1995: I van der Woude; H W Visser; M B ter Beest; A Wagenaar; Marcel H J Ruiters; Jan B F N Engberts; Dick Hoekstra
Parameters influencing the introduction of plasmid DNA into cells by the use of synthetic amphiphiles as a carrier system.
Biochimica et biophysica acta 1995;1240(1):34-40.
1995: Jan Willem Kok; T Babia; Karin Klappe; Dick Hoekstra
Fluorescent, short-chain C6-NBD-sphingomyelin, but not C6-NBD-glucosylceramide, is subject to extensive degradation in the plasma membrane: implications for signal transduction related to cell differentiation.
The Biochemical journal 1995;309 ( Pt 3)():905-12.
1995: Michel Vidal; Dick Hoekstra
In vitro fusion of reticulocyte endocytic vesicles with liposomes.
The Journal of biological chemistry 1995;270(30):17823-9.
1994: E G Arts; S Jager; Dick Hoekstra
Evidence for the existence of lipid-diffusion barriers in the equatorial segment of human spermatozoa.
The Biochemical journal 1994;304 ( Pt 1)():211-8.
1994: M B ter Beest; K Hoekstra; A Sein; Dick Hoekstra
Reconstitution of proteolipid protein: some properties and its role in interlamellar attachment.
The Biochemical journal 1994;300 ( Pt 2)():545-52.
1994: T Babia; Jan Willem Kok; M van der Haar; R Kalicharan; Dick Hoekstra
Transport of biosynthetic sphingolipids from Golgi to plasma membrane in HT29 cells: involvement of different carrier vesicle populations.
European journal of cell biology 1994;63(2):172-81.
1994: K J Zaal; Jan Willem Kok; Raija Sormunen; Sinikka Eskelinen; Dick Hoekstra
Intracellular sites involved in the biogenesis of bile canaliculi in hepatic cells.
European journal of cell biology 1994;63(1):10-9.
1993: Dick Hoekstra; R Buist-Arkema; Karin Klappe; C P Reutelingsperger
Interaction of annexins with membranes: the N-terminus as a governing parameter as revealed with a chimeric annexin.
Biochemistry 1993;32(51):14194-202.
1993: E G Arts; J Kuiken; S Jager; Dick Hoekstra
Fusion of artificial membranes with mammalian spermatozoa. Specific involvement of the equatorial segment after acrosome reaction.
European journal of biochemistry / FEBS 1993;217(3):1001-9.
1993: Hans De Vries; C Schrage; K Hoekstra; Jan Willem Kok; M E van der Haar; Dharamdajal Kalicharan; R S Liem; J C V M Copray; Dick Hoekstra
Outstations of the Golgi complex are present in the processes of cultured rat oligodendrocytes.
Journal of neuroscience research 1993;36(3):336-43.
1993: T Babia; Jan Willem Kok; C Hulstaert; Henk de Weerd; Dick Hoekstra
Differential metabolism and trafficking of sphingolipids in differentiated versus undifferentiated HT29 cells.
International journal of cancer. Journal international du cancer 1993;54(5):839-45.
1993: Eveline van der Veer; D Van der Weide; H S Heijmans; Dick Hoekstra
Translocation of fluorescent ether phospholipid, but not its diacyl counterpart, after insertion in plasma membranes of control and plasmalogen-deficient fibroblasts.
Biochimica et biophysica acta 1993;1146(2):294-300.
1993: M B ter Beest; Dick Hoekstra
Interaction of myelin basic protein with artificial membranes. Parameters governing binding, aggregation and dissociation.
European journal of biochemistry / FEBS 1993;211(3):689-96.
1993: Dick Hoekstra; Karin Klappe
Fluorescence assays to monitor fusion of enveloped viruses.
Methods in enzymology 1993;220():261-76.
1993: Dick Hoekstra; N Düzgüneş
Lipid mixing assays to determine fusion in liposome systems.
Methods in enzymology 1993;220():15-32.
1992: Dick Hoekstra; Jan Willem Kok
Trafficking of glycosphingolipids in eukaryotic cells; sorting and recycling of lipids.
Biochimica et biophysica acta 1992;1113(3-4):277-94.
1992: Jan Willem Kok; K Hoekstra; Sinikka Eskelinen; Dick Hoekstra
Recycling pathways of glucosylceramide in BHK cells: distinct involvement of early and late endosomes.
Journal of cell science 1992;103 ( Pt 4)():1139-52.
1992: T A Fonteijn; Jan B F N Engberts; Shlomo Nir; Dick Hoekstra
Asymmetric fusion between synthetic di-n-dodecylphosphate vesicles and virus membranes.
Biochimica et biophysica acta 1992;1110(2):185-92.
1992: Henkjan J Verkade; K J Zaal; J T Derksen; roel vonk; Dick Hoekstra; Folkert Kuipers; Gerrit L Scherphof
Processing of the phospholipid analogue phosphatidyl(N-sulphorhodamine B sulphonyl)ethanolamine by rat hepatocytes in vitro and in vivo.
The Biochemical journal 1992;284 ( Pt 1)():259-65.
1992: J Seppen; João Ramalho-Santos; A P de Carvalho; M ter Beest; Jan Willem Kok; Maria C Pedroso de Lima; Dick Hoekstra
Interaction of clathrin with large unilamellar phospholipid vesicles at neutral pH. Lipid dependence and protein penetration.
Biochimica et biophysica acta 1992;1106(1):209-15.
1991: Maria C Pedroso De Lima; Shlomo Nir; Diana L Flasher; Karin Klappe; Dick Hoekstra; N Düzgüneş
Fusion of Sendai virus with human HL-60 and CEM cells: different kinetics of fusion for two isolates.
Biochimica et biophysica acta 1991;1070(2):446-54.
1991: Sinikka Eskelinen; Jan Willem Kok; Raija Sormunen; Dick Hoekstra
Coated endosomal vesicles: sorting and recycling compartment for transferrin in BHK cells.
European journal of cell biology 1991;56(2):210-22.
1991: Jan Willem Kok; T Babia; Dick Hoekstra
Sorting of sphingolipids in the endocytic pathway of HT29 cells.
The Journal of cell biology 1991;114(2):231-9.
1991: T A Fonteijn; Jan B F N Engberts; Dick Hoekstra
Asymmetric fusion between phospholipid vesicles and vesicles formed from synthetic di(n-alkyl)phosphates.
Biochemistry 1991;30(21):5319-24.
1990: J Willem; M ter Beest; Gerrit L Scherphof; Dick Hoekstra
A non-exchangeable fluorescent phospholipid analog as a membrane traffic marker of the endocytic pathway.
European journal of cell biology 1990;53(1):173-84.
1990: Dick Hoekstra
Fluorescence assays to monitor membrane fusion: potential application in biliary lipid secretion and vesicle interactions.
Hepatology (Baltimore, Md.) 1990;12(3 Pt 2):61S-66S.
1990: Dick Hoekstra
Membrane fusion of enveloped viruses: especially a matter of proteins.
Journal of bioenergetics and biomembranes 1990;22(2):121-55.
1989: Jan Willem Kok; Sinikka Eskelinen; K Hoekstra; Dick Hoekstra
Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9896-900.
1989: H J Marvin; M B ter Beest; Dick Hoekstra; Bernard Witholt
Fusion of small unilamellar vesicles with viable EDTA-treated Escherichia coli cells.
Journal of bacteriology 1989;171(10):5268-75.
1989: Dick Hoekstra; Jan Willem Kok
Entry mechanisms of enveloped viruses. Implications for fusion of intracellular membranes.
Bioscience reports 1989;9(3):273-305.
1989: Dick Hoekstra; Karin Klappe; H Hoff; Shlomo Nir
Mechanism of fusion of Sendai virus: role of hydrophobic interactions and mobility constraints of viral membrane proteins. Effects of polyethylene glycol.
The Journal of biological chemistry 1989;264(12):6786-92.
1988: L A Rupert; Jan B F N Engberts; Dick Hoekstra
Effect of poly(ethylene glycol) on the Ca2+-induced fusion of didodecyl phosphate vesicles.
Biochemistry 1988;27(21):8232-9.
1987: L A Rupert; JF van Breemen; E F van Bruggen; Jan B F N Engberts; Dick Hoekstra
Calcium-induced fusion of didodecylphosphate vesicles: the lamellar to hexagonal II (HII) phase transition.
The Journal of membrane biology 1987;95(3):255-63.
1986: Shlomo Nir; Karin Klappe; Dick Hoekstra
Mass action analysis of kinetics and extent of fusion between Sendai virus and phospholipid vesicles.
Biochemistry 1986;25(25):8261-6.
1986: Karin Klappe; J Wilschut; Shlomo Nir; Dick Hoekstra
Parameters affecting fusion between Sendai virus and liposomes. Role of viral proteins, liposome composition, and pH.
Biochemistry 1986;25(25):8252-60.
1986: Shlomo Nir; Karin Klappe; Dick Hoekstra
Kinetics and extent of fusion between Sendai virus and erythrocyte ghosts: application of a mass action kinetic model.
Biochemistry 1986;25(8):2155-61.
1985: A J Driessen; Dick Hoekstra; Gerrit L Scherphof; R D Kalicharan; Jan Wilschut
Low pH-induced fusion of liposomes with membrane vesicles derived from Bacillus subtilis.
The Journal of biological chemistry 1985;260(19):10880-7.
1985: Dick Hoekstra; Karin Klappe; T de Boer; J Wilschut
Characterization of the fusogenic properties of Sendai virus: kinetics of fusion with erythrocyte membranes.
Biochemistry 1985;24(18):4739-45.
1984: Dick Hoekstra; T de Boer; Karin Klappe; J Wilschut
Fluorescence method for measuring the kinetics of fusion between biological membranes.
Biochemistry 1984;23(24):5675-81.