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René Hoet

Research Profile

Chemicals & Drugs

Anatomy

B-Lymphocytes

Disorders

Lupus Erythematosus, Systemic

Genes & Molecular Sequences

Concepts & Ideas

Physiology

Antibody Specificity

Co-author Network

Publications

TOP 3
Ruud M T de Wildt; René M A Hoet
The recovery of immunoglobulin sequences from single human B cells by clonal expansion.
Will Roeffen; Jos M H Raats; Karina Teelen; René M A Hoet; Wijnand Eling; Walther J van Venrooij; Robert W Sauerwein
Recombinant human antibodies specific for the Pfs48/45 protein of the malaria parasite Plasmodium falciparum.
SN Seal; René M A Hoet; Jos M H Raats; Marko Z Radic
Analysis of autoimmune bone marrow by antibody-phage display: somatic mutations and third complementarity-determining region arginines in anti-DNA gamma and kappa V genes.

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All Publications

2002: Ruud M T de Wildt; René M A Hoet
The recovery of immunoglobulin sequences from single human B cells by clonal expansion.
Methods in molecular biology (Clifton, N.J.) 2002;178():121-31.
2001: Will Roeffen; Jos M H Raats; Karina Teelen; René M A Hoet; Wijnand Eling; Walther J van Venrooij; Robert W Sauerwein
Recombinant human antibodies specific for the Pfs48/45 protein of the malaria parasite Plasmodium falciparum.
The Journal of biological chemistry 2001;276(23):19807-11.
2000: SN Seal; René M A Hoet; Jos M H Raats; Marko Z Radic
Analysis of autoimmune bone marrow by antibody-phage display: somatic mutations and third complementarity-determining region arginines in anti-DNA gamma and kappa V genes.
Arthritis and rheumatism 2000;43(9):2132-8.
2000: Ruud M T de Wildt; Ian M Tomlinson; Walther J van Venrooij; Greg Winter; René M A Hoet
Comparable heavy and light chain pairings in normal and systemic lupus erythematosus IgG(+) B cells.
European journal of immunology 2000;30(1):254-61.
1999: Ruud M T de Wildt; Walther J van Venrooij; Greg Winter; René M A Hoet; Ian M Tomlinson
Somatic insertions and deletions shape the human antibody repertoire.
Journal of molecular biology 1999;294(3):701-10.
1999: René M A Hoet; Martijn Pieffers; M H Stassen; Jos M H Raats; Ruud M T de Wildt; Ger J M Pruijn; F Van Den Hoogen; Walther J van Venrooij
The importance of the light chain for the epitope specificity of human anti-U1 small nuclear RNA autoantibodies present in systemic lupus erythematosus patients.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3304-12.
1999: Ruud M T de Wildt; René M A Hoet; Walther J van Venrooij; Ian M Tomlinson; Greg Winter
Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire.
Journal of molecular biology 1999;285(3):895-901.
1998: René M A Hoet; Jos M H Raats; Ruud M T de Wildt; H Dumortier; S Muller; F Van Den Hoogen; Walther J van Venrooij
Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage.
Molecular immunology 1998;35(16):1045-55.
1998: SW Teunissen; M H Stassen; Ger J M Pruijn; Walther J van Venrooij; René M A Hoet
Characterization of an anti-RNA recombinant autoantibody fragment (scFv) isolated from a phage display library and detailed analysis of its binding site on U1 snRNA.
RNA (New York, N.Y.) 1998;4(9):1124-33.
1998: P M Willems; René M A Hoet; E L Huys; Jos M H Raats; E J B M Mensink; Reinier A P Raymakers
Specific detection of myeloma plasma cells using anti-idiotypic single chain antibody fragments selected from a phage display library.
Leukemia 1998;12(8):1295-302.
1998: Toin H van Kuppevelt; Michel A B A Dennissen; Walther J van Venrooij; René M A Hoet; Jacques H Veerkamp
Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney.
The Journal of biological chemistry 1998;273(21):12960-6.
1997: Ruud M T de Wildt; P G Steenbakkers; A H Pennings; F H J van den Hoogen; Walther J van Venrooij; René M A Hoet
A new method for the analysis and production of monoclonal antibody fragments originating from single human B cells.
Journal of immunological methods 1997;207(1):61-7.
1997: Ruud M T de Wildt; R Ruytenbeek; Walther J van Venrooij; René M A Hoet
Heavy chain CDR3 optimization of a germline encoded recombinant antibody fragment predisposed to bind the U1A protein.
Protein engineering 1997;10(7):835-41.
1997: Ruud M T de Wildt; F H J van den Hoogen; Walther J van Venrooij; René M A Hoet
Isolation and characterization of single anti-U1A-specific B cells from autoimmune patients.
Annals of the New York Academy of Sciences 1997;815():440-2.
1996: Ruud M T de Wildt; R Finnern; Willem H Ouwehand; A D Griffiths; Walther J van Venrooij; René M A Hoet
Characterization of human variable domain antibody fragments against the U1 RNA-associated A protein, selected from a synthetic and patient-derived combinatorial V gene library.
European journal of immunology 1996;26(3):629-39.
1993: René M A Hoet; B Kastner; R Lührmann; Walther J van Venrooij
Purification and characterization of human autoantibodies directed to specific regions on U1RNA; recognition of native U1RNP complexes.
Nucleic acids research 1993;21(22):5130-6.
1993: T E Feltkamp; J M Berthelot; A M Boerbooms; H G Geertzen; René M A Hoet; Filip De Keyser; Walther J van Venrooij; Gust Verbruggen; E M Veys; P Youinou
Interlaboratory variability of the antiperinuclear factor (APF) test for rheumatoid arthritis.
Clinical and experimental rheumatology 1993;11(1):57-9.
1992: René M A Hoet; P De Weerd; J K Gunnewiek; I Koornneef; Walther J van Venrooij
Epitope regions on U1 small nuclear RNA recognized by anti-U1RNA-specific autoantibodies.
The Journal of clinical investigation 1992;90(5):1753-62.
1992: René M A Hoet; I Koornneef; D J de Rooij; L B A Van De Putte; Walther J van Venrooij
Changes in anti-U1 RNA antibody levels correlate with disease activity in patients with systemic lupus erythematosus overlap syndrome.
Arthritis and rheumatism 1992;35(10):1202-10.
1992: René M A Hoet; Walther J van Venrooij
B-cell epitopes of RNA autoantigens.
Molecular biology reports 1992;16(3):199-205.
1991: René M A Hoet; A M Boerbooms; M Arends; D J Ruiter; Walther J van Venrooij
Antiperinuclear factor, a marker autoantibody for rheumatoid arthritis: colocalisation of the perinuclear factor and profilaggrin.
Annals of the rheumatic diseases 1991;50(9):611-8.
1991: René M A Hoet; Ralph A C A Voorsmit; Walther J van Venrooij
The perinuclear factor, a rheumatoid arthritis-specific autoantigen, is not present in keratohyalin granules of cultured buccal mucosa cells.
Clinical and experimental immunology 1991;84(1):59-65.
1990: Walther J van Venrooij; René M A Hoet; J Castrop; B Hageman; Iain W Mattaj; L B A Van De Putte
Anti-(U1) small nuclear RNA antibodies in anti-small nuclear ribonucleoprotein sera from patients with connective tissue diseases.
The Journal of clinical investigation 1990;86(6):2154-60.
1988: E C Rietveld; René M A Hoet; F Seutter-Berlage; J M Van Rossum
Percutaneous absorption of 14C-labelled 2-chlorobenzaldehyde in rats. Metabolism and toxicokinetics.
European journal of drug metabolism and pharmacokinetics 1988;13(4):231-40.