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Maureane Hoffman

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All Publications

2012: Maureane Hoffman; Dougald M Monroe
Low intensity laser therapy speeds wound healing in hemophilia by enhancing platelet procoagulant activity.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2012;20(5):770-7.
2012: Dougald M Monroe; Maureane Hoffman
The clotting system - a major player in wound healing.
Haemophilia : the official journal of the World Federation of Hemophilia 2012;18 Suppl 5():11-6.
2012: Maureane Hoffman
Hemostatic properties of the FVIIa analog NN1731.
Thrombosis research 2012;129 Suppl 2():S49-50.
2011: Maureane Hoffman
Hypothesis: hyperhomocysteinemia is an indicator of oxidant stress.
Medical hypotheses 2011;77(6):1088-93.
2011: Derrick L Sauls; Maria Warren; Maureane Hoffman
Homocysteinylated fibrinogen forms disulfide-linked complexes with albumin.
Thrombosis research 2011;127(6):576-81.
2011: Kelly L West; Cory Adamson; Maureane Hoffman
Prophylactic correction of the international normalized ratio in neurosurgery: a brief review of a brief literature.
Journal of neurosurgery 2011;114(1):9-18.
2010: Maureane Hoffman; Dougald M Monroe
Inflammation does not predispose to bleeding in hemophilia.
Journal of thrombosis and haemostasis : JTH 2010;8(11):2583-5.
2010: Maureane Hoffman; Dougald M Monroe
Wound healing in haemophilia--breaking the vicious cycle.
Haemophilia : the official journal of the World Federation of Hemophilia 2010;16 Suppl 3():13-8.
2010: Maureane Hoffman; Dougald M Monroe
Platelet binding and activity of recombinant factor VIIa.
Thrombosis research 2010;125 Suppl 1():S16-8.
2010: Dougald M Monroe; Nigel Mackman; Maureane Hoffman
Wound healing in hemophilia B mice and low tissue factor mice.
Thrombosis research 2010;125 Suppl 1():S74-7.
2009: Shahid M Nimjee; Sabah Oney; Volovyk Zoya; Kristin M Bompiani; Steve B Long; Maureane Hoffman; Bruce A Sullenger
Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin.
RNA (New York, N.Y.) 2009;15(12):2105-11.
2009: Volovyk Zoya; Dougald M Monroe; YiWei Qi; Richard Becker; Maureane Hoffman
A rationally designed heparin, M118, has anticoagulant activity similar to unfractionated heparin and different from Lovenox in a cell-based model of thrombin generation.
Journal of thrombosis and thrombolysis 2009;28(2):132-9.
2009: Maureane Hoffman; Dougald M Monroe
Tissue factor in brain is not saturated with factor VIIa: implications for factor VIIa dosing in intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 2009;40(8):2882-4.
2009: Maureane Hoffman; S Pradhan; Dougald M Monroe
Celecoxib does not delay cutaneous wound healing in haemophilia B mice.
Haemophilia : the official journal of the World Federation of Hemophilia 2009;15(2):615-6.
2009: Dougald M Monroe; Maureane Hoffman
The coagulation cascade in cirrhosis.
Clinics in liver disease 2009;13(1):1-9.
2009: Dougald M Monroe; Maureane Hoffman
Dysregulation of hemostasis by cancer.
Cancer treatment and research 2009;148():3-15.
2008: Maureane Hoffman
FVIIa: you've come a long way, baby!
Blood 2008;112(8):3002-3.
2008: Maureane Hoffman
Alterations of fibrinogen structure in human disease.
Cardiovascular & hematological agents in medicinal chemistry 2008;6(3):206-11.
2008: Anna G McDonald; Katie Yang; Harold R Roberts; Dougald M Monroe; Maureane Hoffman
Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia.
Blood 2008;111(4):2046-8.
2008: Maureane Hoffman
Some things I thought I knew about tissue factor that turn out to be wrong.
Thrombosis research 2008;122 Suppl 1():S73-7.
2007: A McDonald; Maureane Hoffman; Ulla Hedner; Harold R Roberts; Dougald M Monroe
Restoring hemostatic thrombin generation at the time of cutaneous wounding does not normalize healing in hemophilia B.
Journal of thrombosis and haemostasis : JTH 2007;5(8):1577-83.
2007: Dougald M Monroe; Maureane Hoffman; Harold R Roberts
Fathers of modern coagulation.
Thrombosis and haemostasis 2007;98(1):3-5.
2007: Maureane Hoffman; C M Colina; A G McDonald; Gowthami M Arepally; L Pedersen; Dougald M Monroe
Tissue factor around dermal vessels has bound factor VII in the absence of injury.
Journal of thrombosis and haemostasis : JTH 2007;5(7):1403-8.
2007: Derrick L Sauls; Akpene E Banini; L C Boyd; Maureane Hoffman
Elevated prothrombin level and shortened clotting times in subjects with type 2 diabetes.
Journal of thrombosis and haemostasis : JTH 2007;5(3):638-9.
2007: Maureane Hoffman; Dougald M Monroe
Coagulation 2006: a modern view of hemostasis.
Hematology/oncology clinics of North America 2007;21(1):1-11.
2007: Derrick L Sauls; Erin K Arnold; Charles W Bell; Jonathan C Allen; Maureane Hoffman
Pro-thrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia.
Thrombosis research 2007;120(1):117-26.
2006: Maureane Hoffman; Anna Harger; Angela Lenkowski; Ulla Hedner; Harold R Roberts; Dougald M Monroe
Cutaneous wound healing is impaired in hemophilia B.
Blood 2006;108(9):3053-60.
2006: Stephen H Caldwell; Maureane Hoffman; Ton Lisman; B Gail Macik; Patrick G Northup; K Rajender Reddy; Armando Tripodi; Arun J Sanyal
Coagulation disorders and hemostasis in liver disease: pathophysiology and critical assessment of current management.
Hepatology (Baltimore, Md.) 2006;44(4):1039-46.
2006: Geoffrey A Allen; Maureane Hoffman; Harold R Roberts; Dougald M Monroe
Manipulation of prothrombin concentration improves response to high-dose factor VIIa in a cell-based model of haemophilia.
British journal of haematology 2006;134(3):314-9.
2006: Harold R Roberts; Maureane Hoffman; Dougald M Monroe
A cell-based model of thrombin generation.
Seminars in thrombosis and hemostasis 2006;32 Suppl 1():32-8.
2006: Derrick L Sauls; Evelyn Lockhart; Maria Esteban Warren; Angela Lenkowski; Susan E Wilhelm; Maureane Hoffman
Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.
Biochemistry 2006;45(8):2480-7.
2006: Dougald M Monroe; Maureane Hoffman
What does it take to make the perfect clot?
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):41-8.
2005: Alisa S Wolberg; Geoffrey A Allen; Dougald M Monroe; Ulla Hedner; Harold R Roberts; Maureane Hoffman
High dose factor VIIa improves clot structure and stability in a model of haemophilia B.
British journal of haematology 2005;131(5):645-55.
2005: Laura N Glasscock; Sophie M Réhault; Christopher W Gregory; Scott T Cooper; Tracy P Jackson; Maureane Hoffman; Frank Church
Protein C inhibitor (plasminogen activator inhibitor-3) expression in the CWR22 prostate cancer xenograft.
Experimental and molecular pathology 2005;79(1):23-32.
2005: Maureane Hoffman
Excess factor VIII and hypercoagulability.
The Journal of the American Board of Family Practice / American Board of Family Practice 2005;18(4):328; author reply 328.
2005: Christine Luise Kempton; Maureane Hoffman; Harold R Roberts; Dougald M Monroe
Platelet heterogeneity: variation in coagulation complexes on platelet subpopulations.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):861-6.
2005: Maureane Hoffman
One more way that mice and men are different.
Journal of thrombosis and haemostasis : JTH 2005;3(3):448-9.
2004: Maureane Hoffman
The cellular basis of traumatic bleeding.
Military medicine 2004;169(12 Suppl):5-7, 4.
2004: Alisa S Wolberg; Zhi Hong Meng; Dougald M Monroe; Maureane Hoffman
A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function.
The Journal of trauma 2004;56(6):1221-8.
2004: Geoffrey A Allen; Alisa S Wolberg; J A Oliver; Maureane Hoffman; Harold R Roberts; Dougald M Monroe
Impact of procoagulant concentration on rate, peak and total thrombin generation in a model system.
Journal of thrombosis and haemostasis : JTH 2004;2(3):402-13.
2004: Derrick L Sauls; Leon C Boyd; Jonathan C Allen; Maureane Hoffman
Differences in the metabolic response to exogenous homocysteine in juvenile and adult rabbits.
The Journal of nutritional biochemistry 2004;15(2):96-102.
2004: Harold R Roberts; Dougald M Monroe; Maureane Hoffman
Safety profile of recombinant factor VIIa.
Seminars in hematology 2004;41(1 Suppl 1):101-8.
2003: Maureane Hoffman
Laboratory monitoring of high-dose factor VIIa therapy.
Annals of internal medicine 2003;139(9):791.
2003: Zhi Hong Meng; Alisa S Wolberg; Dougald M Monroe; Maureane Hoffman
The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients.
The Journal of trauma 2003;55(5):886-91.
2003: Maureane Hoffman; Kim L M Loh; Virginia K Bond; Diane Palmieri; Julie L Ryan; Frank Church
Localization of heparin cofactor II in injured human skin: a potential role in wound healing.
Experimental and molecular pathology 2003;75(2):109-18.
2003: Maureane Hoffman
A cell-based model of coagulation and the role of factor VIIa.
Blood reviews 2003;17 Suppl 1():S1-5.
2003: Maureane Hoffman
Remodeling the blood coagulation cascade.
Journal of thrombosis and thrombolysis 2003;16(1-2):17-20.
2003: Alex Veldman; Maureane Hoffman; Silke Ehrenforth
New insights into the coagulation system and implications for new therapeutic options with recombinant factor VIIa.
Current medicinal chemistry 2003;10(10):797-811.
2003: Alisa S Wolberg; Dougald M Monroe; Harold R Roberts; Maureane Hoffman
Elevated prothrombin results in clots with an altered fiber structure: a possible mechanism of the increased thrombotic risk.
Blood 2003;101(8):3008-13.
2003: Maureane Hoffman; Dougald M Monroe
The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis.
Disease-a-month : DM 2003;49(1):14-21.
2002: Geoffrey A Allen; Maureane Hoffman; Harold R Roberts; Dougald M Monroe
Recombinant activated factor VII: its mechanism of action and role in the control of hemorrhage.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2002;49(10):S7-14.
2002: Dougald M Monroe; Maureane Hoffman; Harold R Roberts
Platelets and thrombin generation.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(9):1381-9.
2002: Alisa S Wolberg; Don A Gabriel; Maureane Hoffman
Analyzing fibrin clot structure using a microplate reader.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2002;13(6):533-9.
2002: Dougald M Monroe; Maureane Hoffman
Coagulation factor interaction with platelets.
Thrombosis and haemostasis 2002;88(2):179.
2002: Julie A Oliver; Dougald M Monroe; Frank Church; Harold R Roberts; Maureane Hoffman
Activated protein C cleaves factor Va more efficiently on endothelium than on platelet surfaces.
Blood 2002;100(2):539-46.
2002: Maureane Hoffman; Douglas M Monroe; Harold R Roberts
Platelet-dependent action of high-dose factor VIIa.
Blood 2002;100(1):364-5; author reply 365.
2002: Tong Gui; Hui-Feng Lin; Da-Yun Jin; Maureane Hoffman; David L Straight; Harold R Roberts; Darrel W Stafford
Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo.
Blood 2002;100(1):153-8.
2001: R White; Christopher P Rusconi; Elizabeth Scardino; Alisa S Wolberg; J Lawson; Maureane Hoffman; Bruce A Sullenger
Generation of species cross-reactive aptamers using "toggle" SELEX.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(6):567-73.
2001: Maureane Hoffman; Dougald M Monroe
The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis.
Seminars in hematology 2001;38(4 Suppl 12):6-9.
2001: Marianne Kjalke; Mirella Ezban; Dougald M Monroe; Maureane Hoffman; Harold R Roberts; Ulla Hedner
High-dose factor VIIa increases initial thrombin generation and mediates faster platelet activation in thrombocytopenia-like conditions in a cell-based model system.
British journal of haematology 2001;114(1):114-20.
2000: Alisa S Wolberg; R H Kon; Dougald M Monroe; Maureane Hoffman
Coagulation factor XI is a contaminant in intravenous immunoglobulin preparations.
American journal of hematology 2000;65(1):30-4.
2000: Alisa S Wolberg; R H Kon; Dougald M Monroe; Mirella Ezban; Harold R Roberts; Maureane Hoffman
Deencryption of cellular tissue factor is independent of its cytoplasmic domain.
Biochemical and biophysical research communications 2000;272(2):332-6.
2000: Geoffrey A Allen; Dougald M Monroe; Harold R Roberts; Maureane Hoffman
The effect of factor X level on thrombin generation and the procoagulant effect of activated factor VII in a cell-based model of coagulation.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2000;11 Suppl 1():S3-7.
2000: Dougald M Monroe; Maureane Hoffman; Geoffrey A Allen; Harold R Roberts
The factor VII-platelet interplay: effectiveness of recombinant factor VIIa in the treatment of bleeding in severe thrombocytopathia.
Seminars in thrombosis and hemostasis 2000;26(4):373-7.
1998: Dennis W Thomas; Roslyn B Mannon; PJ Mannon; Anne M Latour; J A Oliver; Maureane Hoffman; Oliver Smithies; Beverly H Koller; Thomas M Coffman
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
The Journal of clinical investigation 1998;102(11):1994-2001.
1998: Marianne Kjalke; Dougald M Monroe; Maureane Hoffman; JA Oliver; Mirella Ezban; Harold R Roberts
Active site-inactivated factors VIIa, Xa, and IXa inhibit individual steps in a cell-based model of tissue factor-initiated coagulation.
Thrombosis and haemostasis 1998;80(4):578-84.
1998: Harold R Roberts; Dougald M Monroe; JA Oliver; Jen-Yea Chang; Maureane Hoffman
Newer concepts of blood coagulation.
Haemophilia : the official journal of the World Federation of Hemophilia 1998;4(4):331-4.
1998: Marianne Kjalke; Dougald M Monroe; Maureane Hoffman; JA Oliver; Mirella Ezban; Ulla Hedner; Harold R Roberts
The effects of activated factor VII in a cell-based model for tissue factor-initiated coagulation.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1998;9 Suppl 1():S21-5.
1997: Marianne Kjalke; JA Oliver; Dougald M Monroe; Maureane Hoffman; Mirella Ezban; Ulla Hedner; Harold R Roberts
The effect of active site-inhibited factor VIIa on tissue factor-initiated coagulation using platelets before and after aspirin administration.
Thrombosis and haemostasis 1997;78(4):1202-8.
1996: Dougald M Monroe; Maureane Hoffman; Harold R Roberts
Transmission of a procoagulant signal from tissue factor-bearing cell to platelets.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(4):459-64.
1994: Dougald M Monroe; Harold R Roberts; Maureane Hoffman
Platelet procoagulant complex assembly in a tissue factor-initiated system.
British journal of haematology 1994;88(2):364-71.
1993: Maureane Hoffman; Dougald M Monroe; Harold R Roberts
Platelet activation in patients with thrombotic thrombocytopenic purpura.
American journal of hematology 1993;42(2):182-5.