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Carsten Hoffmann

Research Profile

Procedures

Chemicals & Drugs

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Physiology

Signal Transduction

Anatomy

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Protein Binding

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Veronika Hlavackova; Carsten Hoffmann; Julia Bätz; Jaroslav Blahos; Daniela Frankova; Jean-Philippe Pin; Laurent Prezeau; Ulrike Zabel; Martin J Lohse
Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.
Carsten Hoffmann; Catherine H Berlot; Moritz Bünemann; Peter Hein; Susanne Nuber; Christiane Winkler; Ulrike Zabel; Nicole Ziegler; Martin J Lohse
Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells.
Jan-Hendrik Spille; Alexander Zürn; Carsten Hoffmann; Martin J Lohse; Gregory S Harms
Rotational diffusion of the α(2a) adrenergic receptor revealed by FlAsH labeling in living cells.

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All Publications

2012: Veronika Hlavackova; Carsten Hoffmann; Julia Bätz; Jaroslav Blahos; Daniela Frankova; Jean-Philippe Pin; Laurent Prezeau; Ulrike Zabel; Martin J Lohse
Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.
Science signaling 2012;5(237):ra59.
2012: Carsten Hoffmann; Catherine H Berlot; Moritz Bünemann; Peter Hein; Susanne Nuber; Christiane Winkler; Ulrike Zabel; Nicole Ziegler; Martin J Lohse
Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells.
Molecular pharmacology 2012;82(2):236-45.
2011: Jan-Hendrik Spille; Alexander Zürn; Carsten Hoffmann; Martin J Lohse; Gregory S Harms
Rotational diffusion of the α(2a) adrenergic receptor revealed by FlAsH labeling in living cells.
Biophysical journal 2011;100(4):1139-48.
2011: Nicole Ziegler; Julia Bätz; Ulrike Zabel; Martin J Lohse; Carsten Hoffmann
FRET-based sensors for the human M1-, M3-, and M5-acetylcholine receptors.
Bioorganic & medicinal chemistry 2011;19(3):1048-54.
2010: Carsten Hoffmann
G protein-coupled receptor activation: amino acid movements caught infra-red-handed.
Chembiochem : a European journal of chemical biology 2010;11(16):2247-9.
2010: Carsten Hoffmann; Guido Gaietta; Alexander Zürn; Stephen R Adams; Sonia Terrillon; Mark H Ellisman; Roger Y Tsien; Martin J Lohse
Fluorescent labeling of tetracysteine-tagged proteins in intact cells.
Nature protocols 2010;5(10):1666-77.
2010: Alexander Zürn; Christoph Klenk; Ulrike Zabel; Susanne Reiner; Martin J Lohse; Carsten Hoffmann
Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores.
Bioconjugate chemistry 2010;21(5):853-9.
2010: Monika Maier-Peuschel; Nadine Frölich; Christian Dees; Leif G Hommers; Carsten Hoffmann; Viacheslav O Nikolaev; Martin J Lohse
A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation.
The Journal of biological chemistry 2010;285(12):8793-800.
2009: Susanne Reiner; Nicole Ziegler; Catherine Leon; Kristina Lorenz; Kathrin von Hayn; Christian Gachet; Martin J Lohse; Carsten Hoffmann
beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites.
Molecular pharmacology 2009;76(6):1162-71.
2008: Martin J Lohse; Viacheslav O Nikolaev; Peter Hein; Carsten Hoffmann; Jean-Pierre Vilardaga; Moritz Bünemann
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors.
Trends in pharmacological sciences 2008;29(3):159-65.
2008: Martin J Lohse; Peter Hein; Carsten Hoffmann; Viacheslav O Nikolaev; Jean-Pierre Vilardaga; Moritz Bünemann
Kinetics of G-protein-coupled receptor signals in intact cells.
British journal of pharmacology 2008;153 Suppl 1():S125-32.
2008: Carsten Hoffmann; A Zürn; Moritz Bünemann; Martin J Lohse
Conformational changes in G-protein-coupled receptors-the quest for functionally selective conformations is open.
British journal of pharmacology 2008;153 Suppl 1():S358-66.
2007: Yvonne Selz; Ingo Braasch; Carsten Hoffmann; Cornelia Schmidt; Christina Schultheis; Manfred Schartl; Jean-Nicolas Volff
Evolution of melanocortin receptors in teleost fish: the melanocortin type 1 receptor.
Gene 2007;401(1-2):114-22.
2007: Martin J Lohse; Moritz Bünemann; Carsten Hoffmann; Jean-Pierre Vilardaga; Viacheslav O Nikolaev
Monitoring receptor signaling by intramolecular FRET.
Current opinion in pharmacology 2007;7(5):547-53.
2007: Martin J Lohse; Carsten Hoffmann; Viacheslav O Nikolaev; Jean-Pierre Vilardaga; Moritz Bünemann
Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells.
Advances in protein chemistry 2007;74():167-88.
2006: Peter Hein; Francesca Rochais; Carsten Hoffmann; Sandra Dorsch; Viacheslav O Nikolaev; Stefan Engelhardt; Catherine H Berlot; Martin J Lohse; Moritz Bünemann
Gs activation is time-limiting in initiating receptor-mediated signaling.
The Journal of biological chemistry 2006;281(44):33345-51.
2006: Viacheslav O Nikolaev; Carsten Hoffmann; Moritz Bünemann; Martin J Lohse; Jean-Pierre Vilardaga
Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer.
The Journal of biological chemistry 2006;281(34):24506-11.
2006: Björn Behr; Carsten Hoffmann; Gianluca Ottolina; Karl-Norbert Klotz
Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
The Journal of biological chemistry 2006;281(26):18120-5.
2005: Peter Hein; Monika Frank; Carsten Hoffmann; Martin J Lohse; Moritz Bünemann
Dynamics of receptor/G protein coupling in living cells.
The EMBO journal 2005;24(23):4106-14.
2005: Carsten Hoffmann; Guido Gaietta; Moritz Bünemann; Stephen R Adams; Silke Oberdorff-Maass; Björn Behr; Jean-Pierre Vilardaga; Roger Y Tsien; Mark H Ellisman; Martin J Lohse
A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells.
Nature methods 2005;2(3):171-6.