FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Michael Hoffmann

Research Profile

Living Beings

Physiology

Chemicals & Drugs

Anatomy

Procedures

Flow Cytometry

Co-author Network

Publications

TOP 3
Christian Gille; Bärbel Spring; Lena J Tewes; Jürgen Löffler; Guenther E Dannecker; Michael K Hoffmann; Martin Eichner; Christian F Poets; Thorsten W Orlikowsky
Diminished response to interleukin-10 and reduced antibody-dependent cellular cytotoxicity of cord blood monocyte-derived macrophages.
Thorsten W Orlikowsky; Guenther E Dannecker; Bärbel Spring; Martin Eichner; Michael K Hoffmann; Christian F Poets
Effect of dexamethasone on B7 regulation and T cell activation in neonates and adults.
Juergen Foell; Belkis I Diez-Mendiondo; Oliver H Diez; Ursula Holzer; Peter Ruck; Abhijit S Bapat; Michael K Hoffmann; Robert S Mittler; Guenther E Dannecker
Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Michael Hoffmann (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2006: Christian Gille; Bärbel Spring; Lena J Tewes; Jürgen Löffler; Guenther E Dannecker; Michael K Hoffmann; Martin Eichner; Christian F Poets; Thorsten W Orlikowsky
Diminished response to interleukin-10 and reduced antibody-dependent cellular cytotoxicity of cord blood monocyte-derived macrophages.
Pediatric research 2006;60(2):152-7.
2005: Thorsten W Orlikowsky; Guenther E Dannecker; Bärbel Spring; Martin Eichner; Michael K Hoffmann; Christian F Poets
Effect of dexamethasone on B7 regulation and T cell activation in neonates and adults.
Pediatric research 2005;57(5 Pt 1):656-61.
2004: Juergen Foell; Belkis I Diez-Mendiondo; Oliver H Diez; Ursula Holzer; Peter Ruck; Abhijit S Bapat; Michael K Hoffmann; Robert S Mittler; Guenther E Dannecker
Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance.
Immunology 2004;113(1):89-98.
2003: Juergen Foell; Simona Strahotin; Shawn P O'Neil; Megan McCausland; Carolyn Suwyn; Michael Haber; Praveen N Chander; Abhijit S Bapat; Joy (Xiao-Jie) Yan; Nicholas Chiorazzi; Michael K Hoffmann; Robert S Mittler
CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice.
The Journal of clinical investigation 2003;111(10):1505-18.
2003: Thorsten W Orlikowsky; Bärbel Spring; Guenther E Dannecker; Dietrich Niethammer; Christian F Poets; Michael K Hoffmann
Expression and regulation of B7 family molecules on macrophages (MPhi) in preterm and term neonatal cord blood and peripheral blood of adults.
Cytometry. Part B, Clinical cytometry 2003;53(1):40-7.
2003: Juergen Foell; Megan McCausland; Jennifer Burch; Nicholas Corriazzi; Joy (Xiao-Jie) Yan; Carolyn Suwyn; Shawn P O'Neil; Michael K Hoffmann; Robert S Mittler
CD137-mediated T cell co-stimulation terminates existing autoimmune disease in SLE-prone NZB/NZW F1 mice.
Annals of the New York Academy of Sciences 2003;987():230-5.
2001: Thorsten W Orlikowsky; zhi-qin wang; A Dudhane; Guenther E Dannecker; Dietrich Niethammer; Gary P Wormser; Michael K Hoffmann; Harold W Horowitz
Dexamethasone inhibits CD4 T cell deletion mediated by macrophages from human immunodeficiency virus-infected persons.
The Journal of infectious diseases 2001;184(10):1328-30.
2001: zhi-qin wang; Abhijit S Bapat; RJ Rayanade; A S Dagtas; Michael K Hoffmann
Interleukin-10 induces macrophage apoptosis and expression of CD16 (FcgammaRIII) whose engagement blocks the cell death programme and facilitates differentiation.
Immunology 2001;102(3):331-7.
1999: Robert S Mittler; T S Bailey; K Klussman; MD TrailSmith; Michael K Hoffmann
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy.
The Journal of experimental medicine 1999;190(10):1535-40.
1999: Z q Wang; Harold W Horowitz; Thorsten W Orlikowsky; B I Hahn; V Trejo; Abhijit S Bapat; Robert S Mittler; RJ Rayanade; S Y Yang; Michael K Hoffmann
Polyspecific self-reactive antibodies in individuals infected with human immunodeficiency virus facilitate T cell deletion and inhibit costimulatory accessory cell function.
The Journal of infectious diseases 1999;180(4):1072-9.
1999: zhi-qin wang; Abhijit S Bapat; V Trejo; Thorsten W Orlikowsky; Robert S Mittler; Michael K Hoffmann
MHC class I molecules on CD4 T cells regulate receptor-mediated activation signals.
Cellular immunology 1999;193(1):108-14.
1999: Thorsten W Orlikowsky; Guenther E Dannecker; Z Wang; H Horowitz; Dietrich Niethammer; Michael K Hoffmann
Activation or destruction of T cells via macrophages.
Pathobiology : journal of immunopathology, molecular and cellular biology 1999;67(5-6):298-301.
1999: M Chun; Michael K Hoffmann
Plasmin-depletion therapy. A new approach to overcoming tumor cell drug resistance.
Annals of the New York Academy of Sciences 1999;886():240-2.
1998: Thorsten W Orlikowsky; Z Wang; A Dudhane; Robert S Mittler; V Trejo; Guenther E Dannecker; Dietrich Niethammer; Michael K Hoffmann
Elevated major histocompatibility complex class I expression protects T cells from antibody- and macrophage-mediated deletion.
Immunology 1998;95(3):437-42.
1998: zhi-qin wang; Thorsten W Orlikowsky; A Dudhane; V Trejo; Michael K Hoffmann
Macrophages may activate or destroy T cells with which they form antigen- or coreceptor-mediated cellular conjugates.
Cellular immunology 1998;189(1):74-82.
1998: zhi-qin wang; Harold W Horowitz; Thorsten W Orlikowsky; A Dudhane; A Weinstein; Michael K Hoffmann
Lymphocyte-reactive autoantibodies in human immunodeficiency virus type 1-infected persons facilitate the deletion of CD8 T cells by macrophages.
The Journal of infectious diseases 1998;178(2):404-12.
1998: zhi-qin wang; Thorsten W Orlikowsky; A Dudhane; V Trejo; Guenther E Dannecker; B Pernis; Michael K Hoffmann
Staphylococcal enterotoxin B-induced T-cell anergy is mediated by regulatory T cells.
Immunology 1998;94(3):331-9.
1998: Jasmin Kümmerle-Deschner; Michael K Hoffmann; Dietrich Niethammer; Guenther E Dannecker
Pediatric rheumatology: autoimmune mechanisms and therapeutic strategies.
Immunology today 1998;19(6):250-3.
1997: Thorsten W Orlikowsky; zhi-qin wang; A Dudhane; Harold W Horowitz; G Riethmuller; Michael K Hoffmann
Cytotoxic monocytes in the blood of HIV type 1-infected subjects destroy targeted T cells in a CD95-dependent fashion.
AIDS research and human retroviruses 1997;13(11):953-60.
1997: T Orlikowsky; T Olikowsky; zhi-qin wang; A Dudhane; Harold W Horowitz; B Conti; Michael K Hoffmann
Two distinct pathways of human macrophage differentiation are mediated by interferon-gamma and interleukin-10.
Immunology 1997;91(1):104-8.
1996: A Dudhane; zhi-qin wang; Thorsten W Orlikowsky; Amita Gupta; G P Wormser; Harold W Horowitz; P Kufer; Michael K Hoffmann
AIDS patient monocytes target CD4 T cells for cellular conjugate formation and deletion through the membrane expression of HIV-1 envelope molecules.
AIDS research and human retroviruses 1996;12(10):893-9.
1996: A Dudhane; B Conti; Thorsten W Orlikowsky; zhi-qin wang; N Mangla; Amita Gupta; G P Wormser; Michael K Hoffmann
Monocytes in HIV type 1-infected individuals lose expression of costimulatory B7 molecules and acquire cytotoxic activity.
AIDS research and human retroviruses 1996;12(10):885-92.
1996: H Schultz; A Geiselhart; G Sappler; Dietrich Niethammer; Michael K Hoffmann; Guenther E Dannecker
The superantigen Staphylococcus enterotoxin B induces a strong and accelerated secondary T-cell response rather than anergy.
Immunology 1996;87(1):49-54.
1996: Ulrich Mahlknecht; M Herter; Michael K Hoffmann; Dietrich Niethammer; Guenther E Dannecker
The toxic shock syndrome toxin-1 induces anergy in human T cells in vivo.
Human immunology 1996;45(1):42-5.
1995: zhi-qin wang; A Dudhane; Thorsten W Orlikowsky; Michael K Hoffmann
T cell antigen receptor engagement abrogates CD4-mediated T cell deletion in vivo.
International immunology 1995;7(2):207-11.
1994: zhi-qin wang; Thorsten W Orlikowsky; A Dudhane; Robert S Mittler; M Blum; Elizabeth Lacy; G Riethmüller; Michael K Hoffmann
Deletion of T lymphocytes in human CD4 transgenic mice induced by HIV-gp120 and gp120-specific antibodies from AIDS patients.
European journal of immunology 1994;24(7):1553-7.
1994: zhi-qin wang; A Dudhane; Thorsten W Orlikowsky; K Clarke; X Li; Zbigniew Darzynkiewicz; Michael K Hoffmann
CD4 engagement induces Fas antigen-dependent apoptosis of T cells in vivo.
European journal of immunology 1994;24(7):1549-52.
1994: Guenther E Dannecker; Ulrich Mahlknecht; H Schultz; Michael K Hoffmann; Dietrich Niethammer
Activation of human T cells by the superantigen Staphylococcus enterotoxin B: analysis on a cellular level.
Immunobiology 1994;190(1-2):116-26.
1993: Salaheddine Mécheri; Guenther E Dannecker; D Dennig; P Poncet; Michael K Hoffmann
Anti-histone autoantibodies react specifically with the B cell surface.
Molecular immunology 1993;30(6):549-57.
1993: Guenther E Dannecker; H Schultz; S Mecheri; G Sappler; K Clarke; Dietrich Niethammer; Michael K Hoffmann
Characterization of anergy to the superantigen Staphylococcus enterotoxin B.
Immunodeficiency 1993;4(1-4):137-9.
1993: Guenther E Dannecker; S Mecheri; M Heuser; J Ihle; Michael K Hoffmann; Dietrich Niethammer
Differential expression of T cell receptor variable beta genes on CD4+ and CD8+ T cells: influence by sex linked genes?
Immunobiology 1993;187(1-2):17-23.
1992: Guenther E Dannecker; S Mecheri; K Clarke; A Dudhane; zhi-qin wang; Michael K Hoffmann
A stimulatory Mls-1 superantigen is destroyed by ultraviolet light while other Mtv-7 antigens remain intact. Significance for Mls-1 unresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(11):3463-7.
1992: Michael K Hoffmann; Guenther E Dannecker; S Mecheri
Regulation of T cell function by Mtv-7 gene products.
Seminars in immunology 1992;4(5):337-51.
1992: Guenther E Dannecker; S Mecheri; Michael K Hoffmann
In vivo presentation of Mls-1 antigen by T and B lymphocytes.
Immunobiology 1992;185(1):20-7.
1991: S Mecheri; Guenther E Dannecker; D Dennig; Michael K Hoffmann
B cells control the aggregability of CD4 on T cells through continuous physical interactions.
Immunology 1991;74(4):606-12.
1991: Guenther E Dannecker; S Mecheri; Michael K Hoffmann
Induction of neonatal tolerance to the Mls-1a self-super-antigen. Time kinetics and MHC restriction.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(9):2833-8.
1991: Guenther E Dannecker; S Mecheri; L Staiano-Coico; Michael K Hoffmann
A characteristic Mls-1a response precedes Mls-1a anergy in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2083-7.
1990: S Mecheri; Guenther E Dannecker; D Dennig; Michael K Hoffmann
Immunogenic peptides require an undisturbed phospholipid cell membrane environment and must be amphipathic to immobilize Ia on B cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(4):1369-74.
1990: S Mecheri; Michael Edidin; Guenther E Dannecker; Robert S Mittler; Michael K Hoffmann
Immunogenic Ia-binding peptides immobilize the Ia molecule and facilitate its aggregation on the B cell membrane. Control by the M1s-1 gene.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(4):1361-8.
1989: Robert S Mittler; Michael K Hoffmann
Synergism between HIV gp120 and gp120-specific antibody in blocking human T cell activation.
Science (New York, N.Y.) 1989;245(4924):1380-2.
1988: U Hämmerling; M Toulon; M Chun; S Palfree; Michael K Hoffmann
Bidirectionality of mixed lymphocyte stimulation (Mls) response. Effects of Mlsb stimulator cells on Mlsa helper cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(8):2543-8.
1988: Michael K Hoffmann; M Chun; D Dennig; U Hämmerling
Mls and the helper T-cell repertoire: II. Does the Mls gene product influence the formation of the T-cell repertoire? Studies with Mls tolerance.
Journal of immunogenetics 1988;15(1-3):175-81.
1988: U Hämmerling; M Toulon; R G Palfree; Michael K Hoffmann
Mls and the helper T-cell repertoire. I. Mls as a regulator of T-helper cell activation.
Journal of immunogenetics 1988;15(1-3):169-74.
1988: Michael K Hoffmann
The requirement for high intracellular cyclic adenosine monophosphate concentrations distinguishes two pathways of B cell activation induced with lymphokines and antibody to immunoglobulin.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(2):580-2.
1987: Robert S Mittler; R S Greenfield; B Z Schacter; N F Richard; Michael K Hoffmann
Antibodies to the common leukocyte antigen (T200) inhibit an early phase in the activation of resting human B cells.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(10):3159-66.
1987: Michael K Hoffmann; K M Gilbert; J A Hirst; M Scheid
An essential role for interleukin 1 and a dual function for interleukin 2 in the immune response of murine B lymphocytes to sheep erythrocytes.
The Journal of molecular and cellular immunology : JMCI 1987;3(1):29-36.
1987: M Chun; Michael K Hoffmann
Intracellular cAMP regulates the cytotoxicity of recombinant tumor necrosis factor for L cells in vitro.
Lymphokine research 1987;6(3):161-7.
1987: Michael K Hoffmann
An alternate B cell activation mechanism mediated by macrophages through the release of cyclo-oxygenase pathway products and interleukin 1.
Lymphokine research 1987;6(4):299-308.
1986: Michael K Hoffmann; M Chun; J A Hirst
Conditional requirement for accessory cells in the response of T cells to Con A.
Lymphokine research 1986;5(1):1-9.
1985: M Chun; M Krim; A Granelli-Piperno; J A Hirst; Michael K Hoffmann
Enhancement of cytotoxic activity of natural killer cells by interleukin 2, and antagonism between interleukin 2 and adenosine cyclic monophosphate.
Scandinavian journal of immunology 1985;22(4):375-81.
1985: K M Gilbert; Michael K Hoffmann
cAMP is an essential signal in the induction of antibody production by B cells but inhibits helper function of T cells.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(3):2084-9.
1984: Michael K Hoffmann; S B Mizel; J A Hirst
IL 1 requirement for B cell activation revealed by use of adult serum.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(5):2566-8.
1982: Michael K Hoffmann; S Pollack; Susan E Krown; Robert S Mittler
Deletion of active human suppressor T lymphocytes from peripheral blood by Sephadex G-10 filtration.
Journal of immunological methods 1982;55(3):327-36.
1982: K M Gilbert; Michael K Hoffmann
Lymphokine-induced suppressor B cells.
Immunology 1982;46(3):545-53.
1982: M Chun; Michael K Hoffmann
Modulation of interferon-induced NK cells by interleukin 2 and cAMP.
Lymphokine research 1982;1(4):91-8.
1981: M Chun; Gabriel Fernandes; Michael K Hoffmann
Mechanism of NK cell activation: relationship between Qa5+ NK cells and lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1981;126(1):331-4.