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Patrick Hoffmann

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Matthias Friedrich; Melanie Fuergut; Patrick Hoffmann; Roman Kischel; Patrick A Baeuerle; Christian Brandl; Petra Deegen; Ricarda Finnern; Ralf Lutterbuese; Peter Mueller; Benno Rattel; Doris Rau; Tobias Raum; Joachim Schuhmacher; Jerry W Slootstra; Markus Voelkel; Dieter Zopf; Peter Kufer
Regression of human prostate cancer xenografts in mice by AMG 212/BAY2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens.
Ralf Lutterbuese; Tobias Raum; Roman Kischel; Patrick Hoffmann; Susanne Mangold; Benno Rattel; Matthias Friedrich; Oliver Thomas; Grit Lorenczewski; Doris Rau; Evelyne Schaller; Ines Herrmann; Andreas Wolf; Thomas Urbig; Patrick A Baeuerle; Peter Kufer
T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells.
Jutta Steigerwald; Tobias Raum; Stefan Pflanz; Ronny Cierpka; Susanne Mangold; Doris Rau; Patrick Hoffmann; Majk Kvesic; Christina Zube; Stefanie Linnerbauer; John Lumsden; Mirnaalini Sriskandarajah; Peter Kufer; Patrick A Baeuerle; Jörg Volkland
Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cells.

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All Publications

2012: Matthias Friedrich; Melanie Fuergut; Patrick Hoffmann; Roman Kischel; Patrick A Baeuerle; Christian Brandl; Petra Deegen; Ricarda Finnern; Ralf Lutterbuese; Peter Mueller; Benno Rattel; Doris Rau; Tobias Raum; Joachim Schuhmacher; Jerry W Slootstra; Markus Voelkel; Dieter Zopf; Peter Kufer
Regression of human prostate cancer xenografts in mice by AMG 212/BAY2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens.
Molecular cancer therapeutics 2012;11(12):2664-73.
2010: Ralf Lutterbuese; Tobias Raum; Roman Kischel; Patrick Hoffmann; Susanne Mangold; Benno Rattel; Matthias Friedrich; Oliver Thomas; Grit Lorenczewski; Doris Rau; Evelyne Schaller; Ines Herrmann; Andreas Wolf; Thomas Urbig; Patrick A Baeuerle; Peter Kufer
T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(28):12605-10.
2009: Jutta Steigerwald; Tobias Raum; Stefan Pflanz; Ronny Cierpka; Susanne Mangold; Doris Rau; Patrick Hoffmann; Majk Kvesic; Christina Zube; Stefanie Linnerbauer; John Lumsden; Mirnaalini Sriskandarajah; Peter Kufer; Patrick A Baeuerle; Jörg Volkland
Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cells.
mAbs 2009;1(2):115-27.
2009: Cornelia Haas; Eva Krinner; Klaus Brischwein; Patrick Hoffmann; Ralf Lutterbüse; Bernd Schlereth; Peter Kufer; Patrick A Baeuerle
Mode of cytotoxic action of T cell-engaging BiTE antibody MT110.
Immunobiology 2009;214(6):441-53.
2007: Michael Mølhøj; Sandrine Crommer; Klaus Brischwein; Doris Rau; Mirnaalini Sriskandarajah; Patrick Hoffmann; Peter Kufer; Robert Hofmeister; Patrick A Baeuerle
CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis.
Molecular immunology 2007;44(8):1935-43.
2007: Jörg Volkland; John Lumsden; Michael Mølhøj; Tobias Raum; Susanne Hausmann; Sandra Wissing; Monika Wissinger; Patrick Hoffmann; Mirnaalini Sriskandarajah; Majk Kvesic; Patrick A Baeuerle; Stefan Pflanz
A humanized monoclonal antibody against interleukin-2 that can inactivate the cytokine/receptor complex.
Molecular immunology 2007;44(7):1743-53.
2006: Eva-Maria Krinner; julia hepp; Patrick Hoffmann; Sandra Bruckmaier; Laetitia Petersen; Silke Petsch; Larissa Parr; Ioana Schuster; Susanne Mangold; Grit Lorenczewski; Petra Lutterbüse; Stefan Buziol; Inessa Hochheim; Jörg Volkland; Michael Mølhøj; Mirnaalini Sriskandarajah; Markus Strasser; Christian Itin; Andreas Wolf; Amartya Basu; Karen Yang; David Filpula; Poul Sørensen; Peter Kufer; Patrick A Baeuerle; Tobias Raum
A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration.
Protein engineering, design & selection : PEDS 2006;19(10):461-70.
2005: Patrick Hoffmann; Robert Hofmeister; Klaus Brischwein; Christian Brandl; Sandrine Crommer; Ralf C Bargou; Christian Itin; Nadja Prang; Patrick A Baeuerle
Serial killing of tumor cells by cytotoxic T cells redirected with a CD19-/CD3-bispecific single-chain antibody construct.
International journal of cancer. Journal international du cancer 2005;115(1):98-104.
2002: Torsten Dreier; Grit Lorenczewski; Christian Brandl; Patrick Hoffmann; Uwe Syring; Frank Hanakam; Peter Kufer; Gert Riethmuller; Ralf C Bargou; Patrick A Baeuerle
Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody.
International journal of cancer. Journal international du cancer 2002;100(6):690-7.