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Sebastian Hoffmann

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Toxicology

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TOP 3
Nina Hasiwa; Astrid Hochadel; Sebastian Hoffmann; Felix E Rivera-Mariani; Christoph Rockel; Stefanie Schindler; Ingo Spreitzer; Sandra Stoppelkamp; Kranthi Vysyaraju; Peter Bruegger; Mardas Daneshian; Stefan Fennrich; Thomas Hartung
Evidence for the detection of non-endotoxin pyrogens by the whole blood monocyte activation test.
Philippe Vanparys; Marilyn Aardema; Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.
Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman; Marilyn Aardema; Philippe Vanparys
ECVAM prevalidation study on in vitro cell transformation assays: general outline and conclusions of the study.

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All Publications

2013: Nina Hasiwa; Astrid Hochadel; Sebastian Hoffmann; Felix E Rivera-Mariani; Christoph Rockel; Stefanie Schindler; Ingo Spreitzer; Sandra Stoppelkamp; Kranthi Vysyaraju; Peter Bruegger; Mardas Daneshian; Stefan Fennrich; Thomas Hartung
Evidence for the detection of non-endotoxin pyrogens by the whole blood monocyte activation test.
ALTEX 2013;30(2):169-208.
2012: Philippe Vanparys; Marilyn Aardema; Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.
Mutation research 2012;744(1):111-6.
2012: Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman; Marilyn Aardema; Philippe Vanparys
ECVAM prevalidation study on in vitro cell transformation assays: general outline and conclusions of the study.
Mutation research 2012;744(1):12-9.
2008: Sebastian Hoffmann; Ana Gallegos Saliner; Grace Patlewicz; Chantra Eskes; Valerie Zuang; Andrew P Worth
A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals.
Toxicology letters 2008;180(1):9-20.
2008: Raffaella Corvi; Silvio Albertini; Thomas Hartung; Sebastian Hoffmann; Daniela Maurici; Stefan Pfuhler; Jan van Benthem; Philippe Vanparys
ECVAM retrospective validation of in vitro micronucleus test (MNT).
Mutagenesis 2008;23(4):271-83.
2007: Chantra Eskes; Thomas Cole; Sebastian Hoffmann; Andrew P Worth; Amanda Cockshott; Ingrid Gerner; Valérie Zuang
The ECVAM international validation study on in vitro tests for acute skin irritation: selection of test chemicals.
Alternatives to laboratory animals : ATLA 2007;35(6):603-19.
2007: Horst Spielmann; Sebastian Hoffmann; Manfred Liebsch; Philip A Botham; Julia Fentem; Chantra Eskes; Roland ROGUET; José Cotovio; Thomas Cole; Andrew P Worth; Jon R Heylings; Penny Jones; Catherine Robles; Helena Kandarova; Armin O Gamer; Marina Remmele; rodger curren; Hans Raabe; Amanda Cockshott; Ingrid Gerner; Valérie Zuang
The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test.
Alternatives to laboratory animals : ATLA 2007;35(6):559-601.
2007: Susanne Bremer; Cristian Pellizzer; Sebastian Hoffmann; T Seidle; Thomas Hartung
The development of new concepts for assessing reproductive toxicity applicable to large scale toxicological programmes.
Current pharmaceutical design 2007;13(29):3047-58.
2006: Michael Balls; Patric Amcoff; Susanne Bremer; Silvia Casati; Sandra Coecke; Richard H Clothier; Robert Combes; Raffaella Corvi; rodger curren; Chantra Eskes; Julia Fentem; Laura Gribaldo; Marlies Halder; Thomas Hartung; Sebastian Hoffmann; Leonard Schectman; Laurie Scott; Horst Spielmann; William S Stokes; Raymond R Tice; Drew Wagner; Valérie Zuang
The principles of weight of evidence validation of test methods and testing strategies. The report and recommendations of ECVAM workshop 58.
Alternatives to laboratory animals : ATLA 2006;34(6):603-20.
2006: Stefanie Schindler; Ingo Spreitzer; Bettina Löschner; Sebastian Hoffmann; Kilian Hennes; Marlies Halder; Peter Brügger; Esther Frey; Thomas Hartung; Thomas Montag
International validation of pyrogen tests based on cryopreserved human primary blood cells.
Journal of immunological methods 2006;316(1-2):42-51.
2005: Sebastian Hoffmann; Anja Peterbauer; Stefanie Schindler; Stefan Fennrich; Stephen Poole; Yogesh Mistry; Thomas Montag-Lessing; Ingo Spreitzer; Bettina Löschner; Mirjam van Aalderen; Rogier Bos; Martin Gommer; Ria Nibbeling; Gabriele Werner-Felmayer; Petra Loitzl; Thomas W Jungi; Marija Brcic; Peter Brügger; Esther Frey; Gerard Bowe; Juan Casado; Sandra Coecke; Jan de Lange; Bente Mogster; Lisbeth M Naess; Ingeborg S Aaberge; Albrecht Wendel; Thomas Hartung
International validation of novel pyrogen tests based on human monocytoid cells.
Journal of immunological methods 2005;298(1-2):161-73.
2004: Thomas Hartung; Susanne Bremer; Silvia Casati; Sandra Coecke; Raffaella Corvi; Salvador Fortaner; Laura Gribaldo; Marlies Halder; Sebastian Hoffmann; Annett Janusch Roi; Pilar Prieto; Enrico Sabbioni; Laurie Scott; Andrew P Worth; Valérie Zuang
A modular approach to the ECVAM principles on test validity.
Alternatives to laboratory animals : ATLA 2004;32(5):467-72.
2003: Sonja Von Aulock; Nicolas W J Schröder; Katja Gueinzius; Stephanie Traub; Sebastian Hoffmann; Kathrin Graf; Stefanie Dimmeler; Thomas Hartung; Ralf R Schumann; Corinna Hermann
Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood.
The Journal of infectious diseases 2003;188(6):938-43.
2002: Ingrid Langezaal; Sebastian Hoffmann; Thomas Hartung; Sandra Coecke
Evaluation and prevalidation of an immunotoxicity test based on human whole-blood cytokine release.
Alternatives to laboratory animals : ATLA 2002;30(6):581-95.