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Heinz Höfler

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Marcus Bettstetter; Enken Drecoll; Marcus Feith; Annette Feuchtinger; Heinz Höfler; Gisela Keller; Julia Slotta-Huspenina; Axel Walch; Sabina Berezowska; Rupert Langer
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Cédrik Schöne; Heinz Höfler; Axel Walch
MALDI imaging mass spectrometry in cancer research: combining proteomic profiling and histological evaluation.
Daniel Reim; Tibor Schuster; Jens Siveke; Fabian Vogl; Florian Bassermann; Karen Becker; Helmut Friess; Heinz Höfler; Rupert Langer; Martin Loos; Alexander R Novotny; Christoph Schuhmacher
Prognostic implications of the seventh edition of the international union against cancer classification for patients with gastric cancer: the Western experience of patients treated in a single-center European institution.

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2013: Marcus Bettstetter; Enken Drecoll; Marcus Feith; Annette Feuchtinger; Heinz Höfler; Gisela Keller; Julia Slotta-Huspenina; Axel Walch; Sabina Berezowska; Rupert Langer
Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome.
Human pathology 2013;44(5):829-36.
2013: Cédrik Schöne; Heinz Höfler; Axel Walch
MALDI imaging mass spectrometry in cancer research: combining proteomic profiling and histological evaluation.
Clinical biochemistry 2013;46(6):539-45.
2013: Daniel Reim; Tibor Schuster; Jens Siveke; Fabian Vogl; Florian Bassermann; Karen Becker; Helmut Friess; Heinz Höfler; Rupert Langer; Martin Loos; Alexander R Novotny; Christoph Schuhmacher
Prognostic implications of the seventh edition of the international union against cancer classification for patients with gastric cancer: the Western experience of patients treated in a single-center European institution.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(2):263-71.
2012: Stefanie Avril; Ellen Hahn; Steffen Hauptmann; Heinz Höfler; Cornelia Höss; Marion Kiechle; Katja Specht; Barbara Schmalfeldt
Histopathologic features of ovarian borderline tumors are not predictive of clinical outcome.
Gynecologic oncology 2012;127(3):516-24.
2012: Mareike Elsner; Marcus Feith; Annette Feuchtinger; Heinz Höfler; Gerhard Jung; Uta Jütting; Bernhard Küster; Rupert Langer; Giuseppina Maccarrone; Stefan Maier; Stephan Meding; Martin Nipp; Sandra Rauser; Hakan Sarioglu; Cédrik Schöne; Marius Ueffing; Michaela Aichler; Benjamin Balluff; Horst Zitzelsberger; Axel Walch
MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma.
Journal of proteomics 2012;75(15):4693-704.
2012: Julia Kneissl; Thomas Lorber; Ingo Drexler; Alexander Hapfelmeier; Stefan Heindl; Heinz Höfler; Gisela Keller; Simone Keller; Birgit Luber
Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines.
International journal of oncology 2012;41(2):733-44.
2012: Mithu Raychaudhuri; Tibor Schuster; Ulrike Schwarz-Boeger; Holger Bronger; Theresa Buchner; Heinz Höfler; Katharina Malinowsky; Stefanie Avril
Intratumoral heterogeneity of microRNA expression in breast cancer.
The Journal of molecular diagnostics : JMD 2012;14(4):376-84.
2012: Karina Bauer; Enken Drecoll; Heinz Höfler; Ulrich Nitsche; Robert Rosenberg; Julia Slotta-Huspenina; Claus Hann von Weyhern; Rupert Langer
High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer.
Cellular oncology (Dordrecht) 2012;35(3):197-205.
2012: Katharina Malinowsky; Heiko Mannsperger; Christian Schmidt; Tibor Schuster; Axel Walch; Claudia Wolff; Daniela Berg; Holger Bronger; Heinz Höfler; Ulrike Korf; Karl-Friedrich Becker
uPA and PAI-1-Related Signaling Pathways Differ between Primary Breast Cancers and Lymph Node Metastases.
Translational oncology 2012;5(2):98-104.
2012: Michaela Aichler; Detlef K Bartsch; Markus Brielmeier; Sara Chiblak; Patricia Da Silva-Buttkus; Anna Dürr; Heinz Höfler; Günter Klöppel; Peter Langer; Pawel K Mazur; Karin Müller-Decker; Christopher Seiler; Jens Siveke; Monica Tost; Irene Esposito
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.
The Journal of pathology 2012;226(5):723-34.
2012: Natalie Ludyga; Soile Tapio; Omid Azimzadeh; Sonja Englert; Barbara Grünwald; Heinz Höfler; Michaela Aubele
Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses.
Virchows Archiv : an international journal of pathology 2012;460(2):131-40.
2012: Lukas Bauer; Karen Becker; Alexander Hapfelmeier; Heinz Höfler; Rupert Langer; Alexander Novotny; Katja Ott; Gisela Keller
Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: a NOTCH2, GSK3B and β-catenin gene signature predicts survival.
PloS one 2012;7(9):e44566.
2012: Julia Slotta-Huspenina; Axel Walch; Claudia Wolff; Katharina Malinowsky; Karina Bauer; Lukas Bauer; Karl-Friedrich Becker; Daniela Berg; Marcus Bettstetter; Enken Drecoll; Marcus Feith; Heinz Höfler; Rupert Langer
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.
PloS one 2012;7(7):e41420.
2012: Katharina Malinowsky; Mithu Raychaudhuri; Sabrina Thulke; Claudia Wolff; Karl-Friedrich Becker; Theresa Buchner; Heinz Höfler; Stefanie Avril
Common protein biomarkers assessed by reverse phase protein arrays show considerable intratumoral heterogeneity in breast cancer tissues.
PloS one 2012;7(7):e40285.
2012: Daniela Berg; Holger Bronger; Heinz Höfler; Katharina Malinowsky; Tibor Schuster; Kai Tran; Axel Walch; Claudia Wolff; Karl-Friedrich Becker
Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR.
Journal of cellular physiology 2012;227(1):204-12.
2011: Benjamin Balluff; Herbert Braselmann; Matthias P Ebert; Mareike Elsner; Annette Feuchtinger; Heinz Höfler; Uta Jütting; Giuseppina Maccarrone; Stephan Meding; Alexander Novotny; Sandra Rauser; Hakan Sarioglu; Roland M Schmid; Cedrik Schöne; Christoph Schuhmacher; Marius Ueffing; Horst Zitzelsberger; Axel Walch
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer.
The American journal of pathology 2011;179(6):2720-9.
2011: Benjamin Balluff; Heinz Höfler; Cedrik Schöne; Axel Walch
MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications.
Histochemistry and cell biology 2011;136(3):227-44.
2011: Kathrin Mutze; Alexander R Novotny; Katja Ott; Felix Schumacher; Karen Becker; Alexander Hapfelmeier; Heinz Höfler; Rupert Langer; Gisela Keller
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
European journal of cancer (Oxford, England : 1990) 2011;47(12):1817-25.
2011: Rupert Langer; Jörg Nährig; Sandra Rauser; Marcus Feith; Annette Feuchtinger; Helmut Friess; Heinz Höfler; Axel Walch
Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(7):908-16.
2011: Natalie Ludyga; Nataša Anastasov; Iria Gonzalez-Vasconcellos; Manuela Ram; Heinz Höfler; Michaela Aubele
Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer.
Molecular bioSystems 2011;7(5):1603-12.
2011: Rupert Langer; Karen Becker; Marcus Feith; Helmut Friess; Heinz Höfler; Gisela Keller
Genetic aberrations in primary esophageal melanomas: molecular analysis of c-KIT, PDGFR, KRAS, NRAS and BRAF in a series of 10 cases.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(4):495-501.
2011: Igor Paron; Madhavi Shamarla; Julia Vörös; Sonja Berchtold; Mert Erkan; Heinz Höfler; Irene Esposito
Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway.
PloS one 2011;6(6):e21684.
2011: Claudia Wolff; Katharina Malinowsky; Daniela Berg; Kerstin Schragner; Tibor Schuster; Axel Walch; Holger Bronger; Heinz Höfler; Karl-Friedrich Becker
Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis.
The Journal of pathology 2011;223(1):54-63.
2010: Benjamin Balluff; Mareike Elsner; Andreas Kowarsch; Sandra Rauser; Stephan Meding; Christoph Schuhmacher; Marcus Feith; Ken Herrmann; Christoph Röcken; Roland M Schmid; Heinz Höfler; Axel Walch; Matthias P A Ebert
Classification of HER2/neu status in gastric cancer using a breast-cancer derived proteome classifier.
Journal of proteome research 2010;9(12):6317-22.
2010: Sandra Rauser; Sören-Oliver Deininger; Detlev Suckau; Heinz Höfler; Axel Walch
Approaching MALDI molecular imaging for clinical proteomic research: current state and fields of application.
Expert review of proteomics 2010;7(6):927-41.
2010: Susanne Hipp; Daniela Berg; Bilge Ergin; Tibor Schuster; Alexander Hapfelmeier; Axel Walch; Stefanie Avril; Barbara Schmalfeldt; Heinz Höfler; Karl-Friedrich Becker
Interaction of Snail and p38 mitogen-activated protein kinase results in shorter overall survival of ovarian cancer patients.
Virchows Archiv : an international journal of pathology 2010;457(6):705-13.
2010: Kathrin Mutze; Rupert Langer; Karen Becker; Katja Ott; Alexander R Novotny; Birgit Luber; Alexander Hapfelmeier; Martin Göttlicher; Heinz Höfler; Gisela Keller
Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer.
Annals of surgical oncology 2010;17(12):3336-43.
2010: Rupert Langer; Kathrin Mutze; Karen Becker; Marcus Feith; Katja Ott; Heinz Höfler; Gisela Keller
Expression of class I histone deacetylases (HDAC1 and HDAC2) in oesophageal adenocarcinomas: an immunohistochemical study.
Journal of clinical pathology 2010;63(11):994-8.
2010: Sara Molatore; Sandya Liyanarachchi; Martin Irmler; Aurel Perren; Massimo Mannelli; Tonino Ercolino; Felix Beuschlein; Barbara Jarzab; Jan Wloch; Jacek Ziaja; Saida Zoubaa; Frauke Neff; Johannes Beckers; Heinz Höfler; Michael J Atkinson; Natalia S Pellegata
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(43):18493-8.
2010: Karl-Friedrich Becker; D Berg; K Malinowsky; C Wolff; B Ergin; S Meding; Axel Walch; Heinz Höfler
[Update on protein analysis of fixed tissues].
Der Pathologe 2010;31 Suppl 2():263-7.
2010: D Berg; H Bronger; Axel Walch; Heinz Höfler; Karl-Friedrich Becker
[Analysis of signalling pathways in formalin-fixed breast cancer tissues].
Der Pathologe 2010;31 Suppl 2():296-9.
2010: Michaela Aubele; M Spears; N Ludyga; Herbert Braselmann; A Feuchtinger; K J Taylor; K Lindner; G Auer; K Stering; Heinz Höfler; M Schmitt; John M S Bartlett
In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues.
British journal of cancer 2010;103(5):663-7.
2010: Sandra Rauser; Rupert Langer; Sebastian Tschernitz; Peter Gais; Uta Jütting; Marcus Feith; Heinz Höfler; Axel Walch
High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma.
BMC cancer 2010;10():608.
2010: Sara Molatore; Eva Kiermaier; Christian B Jung; Misu Lee; Elke Pulz; Heinz Höfler; Michael J Atkinson; Natalia S Pellegata
Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.
Molecular cancer 2010;9():116.
2009: Gertraud Stocker; Katja Ott; Nils Henningsen; Karen Becker; Alexander Hapfelmeier; Florian Lordick; Stefan Hois; Susanne Plaschke; Heinz Höfler; Gisela Keller
CyclinD1 and interleukin-1 receptor antagonist polymorphisms are associated with prognosis in neoadjuvant-treated gastric carcinoma.
European journal of cancer (Oxford, England : 1990) 2009;45(18):3326-35.
2009: Gisela Keller; Birgit Geist; Julia Slotta-Huspenina; Rupert Langer; Florian Nagl; Falko Fend; Heinz Höfler; Aurel Perren
Novel multiple, monoallelic KRAS mutations at codon 12 and 13.
International journal of cancer. Journal international du cancer 2009;125(11):2744-5.
2009: Susanne Hipp; Axel Walch; Tibor Schuster; Sascha Losko; Holger Laux; T Bolton; Heinz Höfler; Karl-Friedrich Becker
Activation of epidermal growth factor receptor results in snail protein but not mRNA overexpression in endometrial cancer.
Journal of cellular and molecular medicine 2009;13(9B):3858-67.
2009: Michaela Aubele; Sanja Vidojkovic; Herbert Braselmann; Dominique Ritterswürden; Gert Auer; Mike J Atkinson; Soile Tapio; Heinz Höfler; Sandra Rauser; John M S Bartlett
Overexpression of PTK6 (breast tumor kinase) protein--a prognostic factor for long-term breast cancer survival--is not due to gene amplification.
Virchows Archiv : an international journal of pathology 2009;455(2):117-23.
2009: Daniela M Schulz; Claudia Böllner; Gerry Thomas; Mike Atkinson; Irene Esposito; Heinz Höfler; Michaela Aubele
Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry.
Journal of proteome research 2009;8(7):3430-8.
2009: Nika Kojc; Nina Zidar; Nina Gale; Mario Poljak; Kristina Fujs Komlos; Antonio Cardesa; Heinz Höfler; Karl-Friedrich Becker
Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck.
Virchows Archiv : an international journal of pathology 2009;454(5):549-55.
2009: Thorsten Wiech; Elisabeth Nikolopoulos; Roland Weis; Rupert Langer; Kilian Bartholomé; Jens Timmer; Axel Walch; Heinz Höfler; Martin Werner
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays.
Laboratory investigation; a journal of technical methods and pathology 2009;89(4):385-97.
2009: Ken Herrmann; Axel Walch; Benjamin Balluff; Marc Tänzer; Heinz Höfler; Bernd J Krause; Markus Schwaiger; Helmut Friess; Roland M Schmid; Matthias P A Ebert
Proteomic and metabolic prediction of response to therapy in gastrointestinal cancers.
Nature clinical practice. Gastroenterology & hepatology 2009;6(3):170-83.
2009: Petra Voland; Sophie Besig; Roland Rad; Thomas Braun; Dorothee M Baur; Aurel Perren; Rupert Langer; Heinz Höfler; Christian Prinz
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Neuroendocrinology 2009;89(1):66-78.
2009: Björn L.D.M. Brücher; Gisela Keller; Martin Werner; Ulrike Müller; Silke Lassmann; Antonello Domenico Cabras; Falko Fend; Raymonde Busch; Hubert Stein; Hans-Dieter Allescher; Michael Molls; J Rüdiger Siewert; Heinz Höfler; Katja Specht
Using Q-RT-PCR to measure cyclin D1, TS, TP, DPD, and Her-2/neu as predictors for response, survival, and recurrence in patients with esophageal squamous cell carcinoma following radiochemotherapy.
International journal of colorectal disease 2009;24(1):69-77.
2008: Sylvie Lorenzen; Björn L.D.M. Brücher; Frank B Zimmermann; Hans Geinitz; J Riera; T Schuster; N Roethling; Heinz Höfler; Katja Ott; Christian Peschel; Jörg Rüdiger Siewert; Michael Molls; Florian Lordick
Neoadjuvant continuous infusion of weekly 5-fluorouracil and escalating doses of oxaliplatin plus concurrent radiation in locally advanced oesophageal squamous cell carcinoma: results of a phase I/II trial.
British journal of cancer 2008;99(7):1020-6.
2008: Nina Zidar; Nina Gale; Nika Kojc; Metka Volavsek; Antonio Cardesa; Llucia Alos; Heinz Höfler; Kareen Blechschmidt; Karl-Friedrich Becker
Cadherin-catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck.
Virchows Archiv : an international journal of pathology 2008;453(3):267-74.
2008: Axel Walch; Sandra Rauser; Sören-Oliver Deininger; Heinz Höfler
MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology.
Histochemistry and cell biology 2008;130(3):421-34.
2008: Katja Ott; Florian Lordick; Karen Becker; Kurt Ulm; JörgRüdiger Siewert; Heinz Höfler; Gisela Keller
Glutathione-S-transferase P1, T1 and M1 genetic polymorphisms in neoadjuvant-treated locally advanced gastric cancer: GSTM1-present genotype is associated with better prognosis in completely resected patients.
International journal of colorectal disease 2008;23(8):773-82.
2008: Karl-Friedrich Becker; Christina Schott; Ingrid Becker; Heinz Höfler
Guided protein extraction from formalin-fixed tissues for quantitative multiplex analysis avoids detrimental effects of histological stains.
Proteomics. Clinical applications 2008;2(5):737-43.
2008: Masamichi Bamba; Hiroyuki Sugihara; Karl-Friedrich Becker; Ingrid Becker; Heinz Höfler; Takanori Hattori
A case of multiple diffuse gastric carcinoma with regional expression of mutant E-cadherin.
Virchows Archiv : an international journal of pathology 2008;452(5):581-3.
2008: Axel Walch; Stefan Seidl; Christine Hermannstädter; Sandra Rauser; Joëlle Deplazes; Rupert Langer; Claus Hann von Weyhern; Mario Sarbia; Raymonde Busch; Marcus Feith; Sonja Gillen; Heinz Höfler; Birgit Luber
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(5):544-52.
2008: Anja Bremm; Axel Walch; Margit Fuchs; Jörg Mages; Justus Duyster; Gisela Keller; Christine Hermannstädter; Karl-Friedrich Becker; Sandra Rauser; Rupert Langer; Claus Hann von Weyhern; Heinz Höfler; Birgit Luber
Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations.
Cancer research 2008;68(3):707-14.
2008: Kareen Blechschmidt; Stefanie Sassen; Barbara Schmalfeldt; T Schuster; Heinz Höfler; Karl-Friedrich Becker
The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients.
British journal of cancer 2008;98(2):489-95.
2008: Susanne Hipp; Axel Walch; Tibor Schuster; Heinz Höfler; Karl-Friedrich Becker
Precise measurement of the E-cadherin repressor Snail in formalin-fixed endometrial carcinoma using protein lysate microarrays.
Clinical & experimental metastasis 2008;25(6):679-83.
2008: Margit Fuchs; Christine Hermannstädter; Peter Hutzler; Georg Häcker; Ferdinand Haller; Heinz Höfler; Birgit Luber
Deletion of exon 8 increases cisplatin-induced E-cadherin cleavage.
Experimental cell research 2008;314(1):153-63.
2007: Kareen Blechschmidt; Elisabeth Kremmer; Regina Hollweck; Ioannis Mylonas; Heinz Höfler; Marcus Kremer; Karl-Friedrich Becker
The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2007;16(4):222-8.
2007: Sandra Rauser; Roland Weis; Herbert Braselmann; Marcus Feith; Hubert J Stein; Rupert Langer; Peter Hutzler; Michael Hausmann; Silke Lassmann; Jörg Rüdiger Siewert; Heinz Höfler; Martin Werner; Axel Walch
Significance of HER2 low-level copy gain in Barrett's cancer: implications for fluorescence in situ hybridization testing in tissues.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(17):5115-23.
2007: Rupert Langer; Katja Specht; Karen Becker; Philipp Ewald; Katja Ott; Florian Lordick; Jörg Rüdiger Siewert; Heinz Höfler
Comparison of pretherapeutic and posttherapeutic expression levels of chemotherapy-associated genes in adenocarcinomas of the esophagus treated by 5-fluorouracil- and cisplatin-based neoadjuvant chemotherapy.
American journal of clinical pathology 2007;128(2):191-7.
2007: Natalia S Pellegata; Leticia Quintanilla-Martinez; Gisela Keller; Sandya Liyanarachchi; Heinz Höfler; Michael J Atkinson; Falko Fend
Human pheochromocytomas show reduced p27Kip1 expression that is not associated with somatic gene mutations and rarely with deletions.
Virchows Archiv : an international journal of pathology 2007;451(1):37-46.
2007: Armando Gamboa-Dominguez; Stefan Seidl; Edgardo Reyes-Gutierrez; Christine Hermannstädter; Leticia Quintanilla-Martinez; Raymonde Busch; Heinz Höfler; Falko Fend; Birgit Luber
Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer.
Journal of clinical pathology 2007;60(7):756-61.
2007: Sandra Kunder; Julia Calzada-Wack; Gabriele Hölzlwimmer; Jacqueline Müller; Claudia Kloss; Will Howat; Jörg Schmidt; Heinz Höfler; Madhuri Warren; Leticia Quintanilla-Martinez
A comprehensive antibody panel for immunohistochemical analysis of formalin-fixed, paraffin-embedded hematopoietic neoplasms of mice: analysis of mouse specific and human antibodies cross-reactive with murine tissue.
Toxicologic pathology 2007;35(3):366-75.
2007: Karl-Friedrich Becker; Christina Schott; S Hipp; V Metzger; P Porschewski; R Beck; Jörg Nährig; Ingrid Becker; Heinz Höfler
Quantitative protein analysis from formalin-fixed tissues: implications for translational clinical research and nanoscale molecular diagnosis.
The Journal of pathology 2007;211(3):370-8.
2007: Anja H Wiese; Johannes Auer; Silke Lassmann; Jörg Nährig; Robert Rosenberg; Heinz Höfler; Rüdiger Rüger; Martin Werner
Identification of gene signatures for invasive colorectal tumor cells.
Cancer detection and prevention 2007;31(4):282-95.
2007: Heinz Höfler; Rupert Langer; Katja Ott; Gisela Keller
Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2007;176():33-6.
2007: Karl-Friedrich Becker; Erika Rosivatz; Kareen Blechschmidt; Elisabeth Kremmer; Mario Sarbia; Heinz Höfler
Analysis of the E-cadherin repressor Snail in primary human cancers.
Cells, tissues, organs 2007;185(1-3):204-12.
2006: Katja Ott; Holger Vogelsang; Noemi Marton; Karen Becker; Florian Lordick; Michael Kobl; Christoph Schuhmacher; Alexander R Novotny; James Mueller; Ulrich Fink; Kurt Ulm; Jörg Rüdiger Siewert; Heinz Höfler; Gisela Keller
The thymidylate synthase tandem repeat promoter polymorphism: A predictor for tumor-related survival in neoadjuvant treated locally advanced gastric cancer.
International journal of cancer. Journal international du cancer 2006;119(12):2885-94.
2006: Natalia S Pellegata; Leticia Quintanilla-Martinez; Heide Siggelkow; Elenore Samson; Karin Bink; Heinz Höfler; Falko Fend; Jochen Graw; Michael J Atkinson
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15558-63.
2006: Rudolf Reiter; Peter Gais; Uta Jütting; Miriam K Steuer-Vogt; Anja Pickhard; Karin Bink; Sandra Rauser; Silke Lassmann; Heinz Höfler; Martin Werner; Axel Walch
Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5136-41.
2006: Jörg Nährig; Heinz Höfler; Sylvia H Heywang-Köbrunner; N Prat; D Hölzel; P H Wünsch; A Lebeau
[Experiences of the Bavarian mammography screening program].
Der Pathologe 2006;27(5):387-91.
2006: Maria Concetta Fargnoli; Emma Altobelli; Gisela Keller; Sergio Chimenti; Heinz Höfler; Ketty Peris
Contribution of melanocortin-1 receptor gene variants to sporadic cutaneous melanoma risk in a population in central Italy: a case-control study.
Melanoma research 2006;16(2):175-82.
2006: Silke Lassmann; Michael Hennig; Robert Rosenberg; Jörg Nährig; Joachim Schreglmann; Friedemann Krause; Manuela Poignee-Heger; Hjalmar Nekarda; Heinz Höfler; Martin Werner
Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-up.
International journal of colorectal disease 2006;21(3):238-47.
2006: Erika Rosivatz; Karl-Friedrich Becker; Elisabeth Kremmer; Christina Schott; Kareen Blechschmidt; Heinz Höfler; Mario Sarbia
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract.
Virchows Archiv : an international journal of pathology 2006;448(3):277-87.
2006: Heinz Höfler
[Role of pathology: tumour banks, quality of tissue and more?].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2006;90():46-51.
2005: Rupert Langer; Katja Specht; Karen Becker; Philipp Ewald; Melitta Bekesch; Mario Sarbia; Raymonde Busch; Marcus Feith; Hubert J Stein; Jörg Rüdiger Siewert; Heinz Höfler
Association of pretherapeutic expression of chemotherapy-related genes with response to neoadjuvant chemotherapy in Barrett carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7462-9.
2005: Karin Biedermann; Holger Vogelsang; Ingrid Becker; Susanne Plaschke; Jörg Rüdiger Siewert; Heinz Höfler; Gisela Keller
Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancer.
The Journal of pathology 2005;207(2):199-206.
2005: Gisela Keller; Heinz Höfler; Karl-Friedrich Becker
Molecular medicine of gastric adenocarcinomas.
Expert reviews in molecular medicine 2005;7(17):1-13.
2005: Margit Fuchs; Christine Hermannstädter; Katja Specht; Pjotr Knyazev; Axel Ullrich; Erika Rosivatz; Raymonde Busch; Peter Hutzler; Heinz Höfler; Birgit Luber
Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3.
Journal of cellular physiology 2005;202(3):805-13.
2005: Stephan Schulz; Antonello Domenico Cabras; Marcus Kremer; Gregor Weirich; Thomas Miethke; Hans-Christian Bösmüller; Heinz Höfler; Martin Werner; Falko Fend
Species identification of mycobacteria in paraffin-embedded tissues: frequent detection of nontuberculous mycobacteria.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(2):274-82.
2005: Armando Gamboa-Dominguez; Claudia Dominguez-Fonseca; Yanin Chavarri-Guerra; Roberto Vargas; Edgardo Reyes-Gutierrez; Dan Green; Leticia Quintanilla-Martinez; Birgit Luber; Raymonde Busch; Karl-Friedrich Becker; Ingrid Becker; Heinz Höfler; Falko Fend
E-cadherin expression in sporadic gastric cancer from Mexico: exon 8 and 9 deletions are infrequent events associated with poor survival.
Human pathology 2005;36(1):29-35.
2004: Axel Walch; Katja Specht; Herbert Braselmann; Hubert Stein; Jörg Rüdiger Siewert; Ulrich T Hopt; Heinz Höfler; Martin Werner
Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinoma.
International journal of cancer. Journal international du cancer 2004;112(5):747-53.
2004: Erika Rosivatz; Ingrid Becker; Masamichi Bamba; Christina Schott; Joachim Diebold; Doris Mayr; Heinz Höfler; Karl-Friedrich Becker
Neoexpression of N-cadherin in E-cadherin positive colon cancers.
International journal of cancer. Journal international du cancer 2004;111(5):711-9.
2004: Margit Fuchs; Peter Hutzler; Gabriele Handschuh; Christine Hermannstädter; Ingrid Brunner; Heinz Höfler; Birgit Luber
Dynamics of cell adhesion and motility in living cells is altered by a single amino acid change in E-cadherin fused to enhanced green fluorescent protein.
Cell motility and the cytoskeleton 2004;59(1):50-61.
2004: Mario Sarbia; Karl Friedrich Becker; Heinz Höfler
Pathology of upper gastrointestinal malignancies.
Seminars in oncology 2004;31(4):465-75.
2004: Bettina Albrecht; Michael Hausmann; Horst Zitzelsberger; Hubert Stein; Jörg Rüdiger Siewert; Ulrich T Hopt; Rupert Langer; Heinz Höfler; Martin Werner; Axel Walch
Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes in Barrett's adenocarcinoma.
The Journal of pathology 2004;203(3):780-8.
2004: Gisela Keller; H Vogelsang; Ingrid Becker; Susanne Plaschke; K Ott; Gianpaolo Suriano; Ana Rita Mateus; Raquel Seruca; K Biedermann; David Huntsman; C Döring; E Holinski-Feder; A Neutzling; Jörg Rüdiger Siewert; Heinz Höfler
Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients.
Journal of medical genetics 2004;41(6):e89.
2004: Armando Gamboa-Dominguez; Claudia Dominguez-Fonseca; Leticia Quintanilla-Martinez; Edgardo Reyes-Gutierrez; Dan Green; Arturo Angeles-Angeles; Raymonde Busch; Christine Hermannstädter; Jörg Nährig; Karl-Friedrich Becker; Ingrid Becker; Heinz Höfler; Falko Fend; Birgit Luber
Epidermal growth factor receptor expression correlates with poor survival in gastric adenocarcinoma from Mexican patients: a multivariate analysis using a standardized immunohistochemical detection system.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(5):579-87.
2004: Silke Lassmann; M Bauer; Robert Rosenberg; Hjalmar Nekarda; Richie Soong; Rüdiger Rüger; Heinz Höfler; Martin Werner
Identification of occult tumor cells in node negative lymph nodes of colorectal cancer patients by cytokeratin 20 gene and protein expression.
International journal of colorectal disease 2004;19(2):87-94.
2004: Rupert Langer; Katja Specht; Karen Becker; Philipp Ewald; Mario Sarbia; R Busch; Marcus Feith; H J Stein; Jörg Rüdiger Siewert; Heinz Höfler
[Prediction of response to neoadjuvant chemotherapy in Barrett's carcinoma by quantitative gene expression analysis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2004;88():207-13.
2004: Elena Fricke; Christine Hermannstädter; Gisela Keller; Margit Fuchs; Ingrid Brunner; Raymonde Busch; Heinz Höfler; Karl-Friedrich Becker; Birgit Luber
Effect of wild-type and mutant E-cadherin on cell proliferation and responsiveness to the chemotherapeutic agents cisplatin, etoposide, and 5-fluorouracil.
Oncology 2004;66(2):150-9.
2003: Marcus Kremer; Leticia Quintanilla-Martinez; Margit Fuchs; Armando Gamboa-Dominguez; Sieglinde Haye; Holger Kalthoff; Erika Rosivatz; Christine Hermannstädter; Raymonde Busch; Heinz Höfler; Birgit Luber
Influence of tumor-associated E-cadherin mutations on tumorigenicity and metastasis.
Carcinogenesis 2003;24(12):1879-86.
2003: Karen Becker; James D Mueller; Christoph Schulmacher; Katja Ott; Ulrich Fink; Raymonde Busch; Knut Böttcher; J Rüdiger Siewert; Heinz Höfler
Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy.
Cancer 2003;98(7):1521-30.
2003: Hubert J Stein; Burkhard H A von Rahden; Heinz Höfler; Jörg Rüdiger Siewert
[Carcinoma of the oesophagogastric junction and Barrett's esophagus: an almost clear oncologic model?].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2003;74(8):703-8.
2003: Sandra Hapke; Horst Kessler; Birgit Luber; Anke Benge; Peter Hutzler; Heinz Höfler; Manfred Schmitt; Ute Reuning
Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/Vitronectin interaction.
Biological chemistry 2003;384(7):1073-83.
2003: Jörg Nährig; Thomas Richter; Walther Kuhn; Norbert Avril; Birgit Flatau; Jurgen Kowolik; Heinz Höfler; Martin Werner
Intraoperative examination of sentinel lymph nodes by ultrarapid immunohistochemistry.
The breast journal 2003;9(4):277-81.
2003: Maria Concetta Fargnoli; Sergio Chimenti; Gisela Keller; Heinz Höfler; Ketty Peris
Identification of four novel melanocortin 1 receptor (MC1R) gene variants in a Mediterranean population.
Human mutation 2003;21(6):655.
2003: Katja Ott; Holger Vogelsang; James Mueller; Karen Becker; Martina Müller; Ulrich Fink; Jörg Rüdiger Siewert; Heinz Höfler; Gisela Keller
Chromosomal instability rather than p53 mutation is associated with response to neoadjuvant cisplatin-based chemotherapy in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2307-15.
2003: Leticia Quintanilla-Martinez; Marcus Kremer; Katja Specht; Julia Calzada-Wack; Michaela Nathrath; Robert Schaich; Heinz Höfler; Falko Fend
Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat 3 activation and cyclin D1 dysregulation are mutually exclusive events.
The American journal of pathology 2003;162(5):1449-61.
2003: Iris Zemzoum; Ronald Kates; Jeffrey S Ross; Peer Dettmar; Moshumi Dutta; Cordula Henrichs; Suna Yurdseven; Heinz Höfler; Marion Kiechle; Manfred Schmitt; Nadia Harbeck
Invasion factors uPA/PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(6):1022-8.
2003: Elena Fricke; Gisela Keller; Ingrid Becker; Erika Rosivatz; Christina Schott; Susanne Plaschke; Martina Rudelius; Christine Hermannstädter; Raymonde Busch; Heinz Höfler; Karl-Friedrich Becker; Birgit Luber
Relationship between E-cadherin gene mutation and p53 gene mutation, p53 accumulation, Bcl-2 expression and Ki-67 staining in diffuse-type gastric carcinoma.
International journal of cancer. Journal international du cancer 2003;104(1):60-5.
2003: Gregor Weirich; Jörg Nährig; Uwe Treiber; Carmen Hartmann; Rudolf Hartung; Heinz Höfler; Falko Fend
Immunohistochemical assessment of a testicular tumor in a 63-year-old patient: proposal for an integrated clinicopathologic approach.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2003;11(1):96-100.
2003: Luca Morelli; Teresa Pusiol; Francesco Piscioli; Heinz Höfler; Gregor Weirich; Martin Werner; Antonello Domenico Cabras
Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient: first report of a solitary lesion.
The American Journal of dermatopathology 2003;25(1):28-31.
2003: Heinz Höfler; Karl-Friedrich Becker; G Keller
[Molecular carcinogenesis of the upper gastrointestinal tract].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2003;87():123-9.
2003: Heinz Höfler; Katja Specht; Karl-Friedrich Becker
Molecular analysis of gene expression in tumor pathology.
Advances in experimental medicine and biology 2003;532():19-26.
2002: Erika Rosivatz; Ingrid Becker; Katja Specht; Elena Fricke; Birgit Luber; Raymonde Busch; Heinz Höfler; Karl-Friedrich Becker
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.
The American journal of pathology 2002;161(5):1881-91.
2002: Silke Lassmann; Markus Bauer; Richie Soong; Joachim Schreglmann; Karim Tabiti; Jörg Nährig; Rüdiger Rüger; Heinz Höfler; Martin Werner
Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity.
The Journal of pathology 2002;198(2):198-206.
2002: Katja Specht; Marcus Kremer; Ulrike Müller; Stephan Dirnhofer; Michael Rosemann; Heinz Höfler; Leticia Quintanilla-Martinez; Falko Fend
Identification of cyclin D1 mRNA overexpression in B-cell neoplasias by real-time reverse transcription-PCR of microdissected paraffin sections.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2902-11.
2002: Gregor Weirich; Antonello D Cabras; Stefano Serra; Pierpaolo Coni; Anna M Nurchi; Gavino Faa; Heinz Höfler
Rapid identification of Wilson's disease carriers by denaturing high-performance liquid chromatography.
Preventive medicine 2002;35(3):278-84.
2002: Michaela Nathrath; Virginija Kuosaite; Michael Rosemann; Marcus Kremer; Christopher Poremba; Shigeharu Wakana; Masayuki Yanagi; Walter B J Nathrath; Heinz Höfler; Kenji Imai; Michael J Atkinson
Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.
Oncogene 2002;21(38):5975-80.
2002: K Becker; Heinz Höfler
[Pathology of appendicitis].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2002;73(8):777-81.
2002: Karl-Friedrich Becker; Elisabeth Kremmer; Manfred Eulitz; Stephan Schulz; Jörg Mages; Gabriele Handschuh; Margaret J Wheelock; Anne-Marie Cleton-Jansen; Heinz Höfler; Ingrid Becker
Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies.
The Journal of pathology 2002;197(5):567-74.
2002: Michaela Nathrath; Marcus Kremer; H Letzel; K Remberger; Heinz Höfler; T Ulle
[Expression of genes of potential importance in the response to chemotherapy in osteosarcoma patients].
Klinische Pädiatrie 2002;214(4):230-5.
2002: Thomas Rüdiger; Heinz Höfler; Hans H Kreipe; H Nizze; Ulrich Pfeifer; H Stein; F E Dallenbach; Hans-Peter Fischer; M Mengel; Reinhard von Wasielewski; H K Müller-Hermelink
Quality assurance in immunohistochemistry: results of an interlaboratory trial involving 172 pathologists.
The American journal of surgical pathology 2002;26(7):873-82.
2002: Margit Fuchs; Peter Hutzler; Ingrid Brunner; Jürgen Schlegel; Jörg Mages; Ute Reuning; Sandra Hapke; Justus Duyster; Setsuo Hirohashi; Takuya Genda; Michiie Sakamoto; Florian Uberall; Heinz Höfler; Karl-Friedrich Becker; Birgit Luber
Motility enhancement by tumor-derived mutant E-cadherin is sensitive to treatment with epidermal growth factor receptor and phosphatidylinositol 3-kinase inhibitors.
Experimental cell research 2002;276(2):129-41.
2002: Andreas Fritz; Axel Walch; Kamilla Piotrowska; Michael Rosemann; Ekkehard Schäffer; Karin Weber; Andreas Timper; Gerhild Wildner; Jochen Graw; Heinz Höfler; Michael J Atkinson
Recessive transmission of a multiple endocrine neoplasia syndrome in the rat.
Cancer research 2002;62(11):3048-51.
2002: M Werner; A D Cabras; Heinz Höfler
[Molecular pathologic diagnosis in solid tumors. What is clinically relevant?].
Der Pathologe 2002;23(3):170-3.
2002: Antonello Domenico Cabras; Gregor Weirich; Falko Fend; Jörg Nährig; Cesare Bordi; Heinz Höfler; Martin Werner
Oligoclonality of a "composite" gastric diffuse large B-cell lymphoma with areas of marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type.
Virchows Archiv : an international journal of pathology 2002;440(2):209-14.
2002: Johannes Bange; Dieter Prechtl; Yuri Cheburkin; Katja Specht; Nadia Harbeck; Manfred Schmitt; Tatjana Knyazeva; Susanne Müller; Silvia Gärtner; Irmi Sures; Hongyang Wang; Evgeny Imyanitov; Hans-Ulrich Häring; Pjotr Knayzev; Stefano Iacobelli; Heinz Höfler; Axel Ullrich
Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.
Cancer research 2002;62(3):840-7.
2002: Michaela Aubele; Gert Auer; Herbert Braselmann; Jörg Nährig; Horst Zitzelsberger; Leticia Quintanilla-Martinez; Jan Smida; Axel Walch; Heinz Höfler; Martin Werner
Chromosomal imbalances are associated with metastasis-free survival in breast cancer patients.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2002;24(2-3):77-87.
2002: Michaela Aubele; Martin Werner; Heinz Höfler
Genetic alterations in presumptive precursor lesions of breast carcinomas.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2002;24(2-3):69-76.
2001: G Keller; A Hartmann; J Mueller; Heinz Höfler
Denaturing high pressure liquid chromatography (DHPLC) for the analysis of somatic p53 mutations.
Laboratory investigation; a journal of technical methods and pathology 2001;81(12):1735-7.
2001: Gabriele Handschuh; Birgit Luber; Peter Hutzler; Heinz Höfler; Karl-Friedrich Becker
Single amino acid substitutions in conserved extracellular domains of E-cadherin differ in their functional consequences.
Journal of molecular biology 2001;314(3):445-54.
2001: Axel Walch; Karin Bink; Peter Hutzler; K Böwering; I Letsiou; Horst Zitzelsberger; Herbert Braselmann; Hubert Stein; Heinz Höfler; Martin Werner
Sequential multilocus fluorescence in situ hybridization can detect complex patterns of increased gene dosage at the single cell level in tissue sections.
Laboratory investigation; a journal of technical methods and pathology 2001;81(10):1457-9.
2001: Nadia Harbeck; U Alt; U Berger; Achim Krüger; Christoph Thomssen; Fritz Jänicke; Heinz Höfler; Ronald Kates; Manfred Schmitt
Prognostic impact of proteolytic factors (urokinase-type plasminogen activator, plasminogen activator inhibitor 1, and cathepsins B, D, and L) in primary breast cancer reflects effects of adjuvant systemic therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2757-64.
2001: Antonello Domenico Cabras; S Candidus; Falko Fend; Marcus Kremer; S Schulz; Cesare Bordi; Gregor Weirich; Heinz Höfler; Martin Werner
Biclonality of gastric lymphomas.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):961-7.
2001: Axel Walch; Katja Specht; Karin Bink; Horst Zitzelsberger; Herbert Braselmann; M Bauer; Michaela Aubele; Hubert Stein; Jörg Rüdiger Siewert; Heinz Höfler; Martin Werner
Her-2/neu gene amplification, elevated mRNA expression, and protein overexpression in the metaplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus.
Laboratory investigation; a journal of technical methods and pathology 2001;81(6):791-801.
2001: Karin Bink; Axel Walch; A Feuchtinger; H Eisenmann; Peter Hutzler; Heinz Höfler; Martin Werner
TO-PRO-3 is an optimal fluorescent dye for nuclear counterstaining in dual-colour FISH on paraffin sections.
Histochemistry and cell biology 2001;115(4):293-9.
2001: Axel Walch; Katja Specht; Jan Smida; Michaela Aubele; Horst Zitzelsberger; Heinz Höfler; Martin Werner
Tissue microdissection techniques in quantitative genome and gene expression analyses.
Histochemistry and cell biology 2001;115(4):269-76.
2001: I J Chalmers; Michaela Aubele; E Hartmann; E Braungart; Martin Werner; Heinz Höfler; Michael J Atkinson
Mapping the chromosome 16 cadherin gene cluster to a minimal deleted region in ductal breast cancer.
Cancer genetics and cytogenetics 2001;126(1):39-44.
2001: M Werner; K F Becker; G Keller; Heinz Höfler
Gastric adenocarcinoma: pathomorphology and molecular pathology.
Journal of cancer research and clinical oncology 2001;127(4):207-16.
2001: Marcus Kremer; M Sandherr; B Geist; Antonello Domenico Cabras; Heinz Höfler; Falko Fend
Epstein-Barr virus-negative Hodgkin's lymphoma after mycosis fungoides: molecular evidence for distinct clonal origin.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(2):91-7.
2001: Dieter Prechtel; Nadia Harbeck; U Berger; Heinz Höfler; AK Werenskiold
Clinical relevance of T1-S, an oncogene-inducible, secreted glycoprotein of the immunoglobulin superfamily, in node-negative breast cancer.
Laboratory investigation; a journal of technical methods and pathology 2001;81(2):159-65.
2001: Katja Specht; Thomas Richter; Ulrike Müller; Axel Walch; Martin Werner; Heinz Höfler
Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue.
The American journal of pathology 2001;158(2):419-29.
2001: Heinz Höfler
[Organization and contents of future research in pathology].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2001;85():37-43.
2001: Axel Walch; Karin Bink; Peter Hutzler; Horst Zitzelsberger; Herbert Braselmann; Michaela Aubele; Heinz Höfler; Martin Werner
[Oncogene amplification and genetic heterogeneity in the metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2001;85():257-63.
2001: E Braungart; E Hartman; K Bechler; Heinz Höfler; Michael J Atkinson
The intracellular domain of cadherin-11 is not required for the induction of cell aggregation, adhesion or gap-junction formation.
Cell communication & adhesion 2001;8(1):15-27.
2001: Horst Zitzelsberger; D Engert; Axel Walch; U Kulka; Michaela Aubele; Heinz Höfler; M Bauchinger; Martin Werner
Chromosomal changes during development and progression of prostate adenocarcinomas.
British journal of cancer 2001;84(2):202-8.
2000: J Mueller; B Brebeck; Barbara Schmalfeldt; W Kuhn; Henner Graeff; Heinz Höfler
Stromelysin-3 expression in invasive ovarian carcinomas and tumours of low malignant potential.
Virchows Archiv : an international journal of pathology 2000;437(6):618-24.
2000: M Yanagi; G Keller; J Mueller; A Walch; M Werner; Hubert J Stein; Jörg Rüdiger Siewert; Heinz Höfler
Comparison of loss of heterozygosity and microsatellite instability in adenocarcinomas of the distal esophagus and proximal stomach.
Virchows Archiv : an international journal of pathology 2000;437(6):605-10.
2000: T Grundei; H Vogelsang; Katja Ott; J Mueller; M Scholz; Karen Becker; Ulrich Fink; Jörg Rüdiger Siewert; Heinz Höfler; G Keller
Loss of heterozygosity and microsatellite instability as predictive markers for neoadjuvant treatment in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4782-8.
2000: Axel Walch; Karin Bink; Peter Hutzler; Heinz Höfler; Martin Werner
HER-2/neu gene amplification by FISH predicts poor survival in Barrett's esophagus-associated adenocarcinoma.
Human pathology 2000;31(10):1332-4.
2000: A D Cabras; M Kremer; S Schulz; M Werner; M Hummel; P Komminoth; Gerald Hoefler; Heinz Höfler
Quality assessment in diagnostic molecular pathology: experience from a German-Austrian-Swiss multicenter trial.
Virchows Archiv : an international journal of pathology 2000;437(1):46-51.
2000: Axel Walch; Horst Zitzelsberger; Karin Bink; Peter Hutzler; J Bruch; Herbert Braselmann; Michaela Aubele; J Mueller; Hubert Stein; Jörg Rüdiger Siewert; Heinz Höfler; Martin Werner
Molecular genetic changes in metastatic primary Barrett's adenocarcinoma and related lymph node metastases: comparison with nonmetastatic Barrett's adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(7):814-24.
2000: S Schulz; Karl-Friedrich Becker; E Braungart; C Reichmuth; Barbara Klamt; Ingrid Becker; M Atkinson; Manfred Gessler; Heinz Höfler
Molecular analysis of E-cadherin and cadherin-11 in Wilms' tumours.
The Journal of pathology 2000;191(2):162-9.
2000: Jörg Nährig; Thomas Richter; Jurgen Kowolik; Walther Kuhn; Norbert Avril; Heinz Höfler; Martin Werner
Comparison of different histopathological methods for the examination of sentinel lymph nodes in breast cancer.
Anticancer research 2000;20(3B):2209-12.
2000: Birgit Luber; S Candidus; Gabriele Handschuh; E Mentele; Peter Hutzler; S Feller; J Voss; Heinz Höfler; Karl-Friedrich Becker
Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate.
Cell adhesion and communication 2000;7(5):391-408.
2000: Margaret C Cummings; Michaela Aubele; AE Mattis; David Purdie; Peter Hutzler; Heinz Höfler; Martin Werner
Increasing chromosome 1 copy number parallels histological progression in breast carcinogenesis.
British journal of cancer 2000;82(6):1204-10.
2000: AK Werenskiold; Dieter Prechtel; Nadia Harbeck; Heinz Höfler
Tumor-associated overexpression of the soluble T1-S receptor in lymph node-negative breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2000;9(1):26-34.
2000: Michaela Aubele; M C Cummings; AE Mattis; Horst Zitzelsberger; Axel Walch; Marcus Kremer; Heinz Höfler; Martin Werner
Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2000;9(1):14-9.
2000: Axel Walch; Horst Zitzelsberger; J Bruch; G Keller; D Angermeier; Michaela Aubele; J Mueller; Hubert Stein; Herbert Braselmann; Jörg Rüdiger Siewert; Heinz Höfler; Martin Werner
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence.
The American journal of pathology 2000;156(2):555-66.
2000: Christoph Schuhmacher; Karen Becker; Hans-Joachim Dittler; Heinz Höfler; Jörg Rüdiger Siewert; Hubert J Stein
Fibrovascular esophageal polyp as a diagnostic challenge.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2000;13(4):324-7.
2000: Axel Walch; Karin Bink; Peter Gais; S Stangl; Peter Hutzler; Michaela Aubele; J Mueller; Heinz Höfler; Martin Werner
Evaluation of c-erbB-2 overexpression and Her-2/neu gene copy number heterogeneity in Barrett's adenocarcinoma.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2000;20(1):25-32.
2000: Axel Walch; P Komminoth; Peter Hutzler; Michaela Aubele; Heinz Höfler; Martin Werner
Microdissection of tissue sections: application to the molecular genetic characterisation of premalignant lesions.
Pathobiology : journal of immunopathology, molecular and cellular biology 2000;68(1):9-17.
2000: Michaela Aubele; AE Mattis; Horst Zitzelsberger; Axel Walch; Marcus Kremer; Gerhard Welzl; Heinz Höfler; Martin Werner
Extensive ductal carcinoma In situ with small foci of invasive ductal carcinoma: evidence of genetic resemblance by CGH.
International journal of cancer. Journal international du cancer 2000;85(1):82-6.
1999: Karl-Friedrich Becker; Elisabeth Kremmer; Manfred Eulitz; Ingrid Becker; Gabriele Handschuh; Christoph Schuhmacher; W Müller; H E Gabbert; A Ochiai; S Hirohashi; Heinz Höfler
Analysis of E-cadherin in diffuse-type gastric cancer using a mutation-specific monoclonal antibody.
The American journal of pathology 1999;155(6):1803-9.
1999: Martin Werner; AE Mattis; Michaela Aubele; M Cummings; Horst Zitzelsberger; Peter Hutzler; Heinz Höfler
20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast.
Virchows Archiv : an international journal of pathology 1999;435(5):469-72.
1999: T D'Adda; S Candidus; H Denk; Cesare Bordi; Heinz Höfler
Gastric neuroendocrine neoplasms: tumour clonality and malignancy-associated large X-chromosomal deletions.
The Journal of pathology 1999;189(3):394-401.
1999: G Keller; H Vogelsang; Ingrid Becker; J Hutter; K Ott; S Candidus; T Grundei; Karl-Friedrich Becker; J Mueller; J R Siewert; Heinz Höfler
Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation.
The American journal of pathology 1999;155(2):337-42.
1999: Gabriele Handschuh; S Candidus; Birgit Luber; Uli Reich; Christina Schott; S Oswald; H Becke; Peter Hutzler; W Birchmeier; Heinz Höfler; Karl-Friedrich Becker
Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility.
Oncogene 1999;18(30):4301-12.
1999: Christoph Schuhmacher; Karl-Friedrich Becker; Uli Reich; U Schenk; J Mueller; Jörg Rüdiger Siewert; Heinz Höfler
Rapid detection of mutated E-cadherin in peritoneal lavage specimens from patients with diffuse-type gastric carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1999;8(2):66-70.
1999: Christoph Schuhmacher; I Becker; S Oswald; Michael J Atkinson; H Nekarda; Karl-Friedrich Becker; J Mueller; Jörg Rüdiger Siewert; Heinz Höfler
Loss of immunohistochemical E-cadherin expression in colon cancer is not due to structural gene alterations.
Virchows Archiv : an international journal of pathology 1999;434(6):489-95.
1999: Nadia Harbeck; P Dettmar; Christoph Thomssen; U Berger; Kurt Ulm; Ronald Kates; Heinz Höfler; Fritz Jänicke; Henner Graeff; Manfred Schmitt
Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers: 6-year median follow-up.
British journal of cancer 1999;80(3-4):419-26.
1999: AK Werenskiold; J Schmidt; B Rupp; W Gössner; Heinz Höfler
Suppression of T1-receptor expression by antisense RNA abrogates differentiation of osteogenic osteosarcoma cells.
Laboratory investigation; a journal of technical methods and pathology 1999;79(5):529-36.
1999: Michaela Aubele; AE Mattis; Horst Zitzelsberger; Axel Walch; Marcus Kremer; Peter Hutzler; Heinz Höfler; Martin Werner
Intratumoral heterogeneity in breast carcinoma revealed by laser-microdissection and comparative genomic hybridization.
Cancer genetics and cytogenetics 1999;110(2):94-102.
1999: E Braungart; C Schumacher; E Hartmann; H Nekarda; Karl-Friedrich Becker; Heinz Höfler; Michael J Atkinson
Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer.
The Journal of pathology 1999;187(5):530-4.
1999: Martin Werner; J Mueller; Axel Walch; Heinz Höfler
The molecular pathology of Barrett's esophagus.
Histology and histopathology 1999;14(2):553-9.
1999: W Kuhn; Barbara Schmalfeldt; Ute Reuning; L Pache; U Berger; Kurt Ulm; Nadia Harbeck; K Späthe; P Dettmar; Heinz Höfler; Fritz Jänicke; Manfred Schmitt; Henner Graeff
Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc.
British journal of cancer 1999;79(11-12):1746-51.
1999: Karen Becker; U Fumagalli; James D Mueller; Ulrich Fink; Jörg Rüdiger Siewert; Heinz Höfler
Neoadjuvant chemotherapy for patients with locally advanced gastric carcinoma: effect on tumor cell microinvolvement of regional lymph nodes.
Cancer 1999;85(7):1484-9.
1999: Nadia Harbeck; Christoph Thomssen; U Berger; Kurt Ulm; Ronald Kates; Heinz Höfler; Fritz Jänicke; Henner Graeff; Manfred Schmitt
Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse.
Breast cancer research and treatment 1999;54(2):147-57.
1999: Ingrid Becker; Karl-Friedrich Becker; Elisabeth Kremmer; Manfred Eulitz; Gabriele Handschuh; Heinz Höfler
[Novel mutation-specific monoclonal E-cadherin antibodies make possible allele differentiation at the protein level in tumors].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():233-9.
1999: Heinz Höfler
[Diffuse stomach carcinoma: from H&E diagnosis and molecular pathology to specific therapy].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():148-54.
1999: J Mueller; E Mueller; G Keller; Birgit Bethke; Manfred Stolte; Heinz Höfler
[Are there differences between ex adenoma and de novo colorectal carcinomas?].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():139-47.
1999: Uta Jütting; Peter Gais; Karsten Rodenacker; J Böhm; S Koch; HW Präuer; Heinz Höfler
Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high resolution image analysis.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1999;18(2):109-19.
1999: M A Markus; C Reichmuth; Michael J Atkinson; U Reich; I Hoffmann; Rudi Balling; U Anderer; Heinz Höfler
Cadherin-11 is highly expressed in rhabdomyosarcomas and during differentiation of myoblasts in vitro.
The Journal of pathology 1999;187(2):164-72.
1999: Karl-Friedrich Becker; Uli Reich; Christina Schott; Ingrid Becker; Geert Berx; F van Roy; Heinz Höfler
Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online.
Human mutation 1999;13(2):171.
1998: Michaela Aubele; Horst Zitzelsberger; U Schenck; Axel Walch; Heinz Höfler; Martin Werner
Distinct cytogenetic alterations in squamous intraepithelial lesions of the cervix revealed by laser-assisted microdissection and comparative genomic hybridization.
Cancer 1998;84(6):375-9.
1998: James D Mueller; N Haegle; G Keller; E Mueller; G Saretzky; Birgit Bethke; Manfred Stolte; Heinz Höfler
Loss of heterozygosity and microsatellite instability in de novo versus ex-adenoma carcinomas of the colorectum.
The American journal of pathology 1998;153(6):1977-84.
1998: James D Mueller; Karl-Heinz Heider; Georg Oberhuber; E Mueller; Birgit Bethke; Manfred Stolte; Heinz Höfler
Comparison of CD44 expression in early colorectal carcinomas of the de novo and ex adenoma types.
Virchows Archiv : an international journal of pathology 1998;433(5):407-14.
1998: Horst Zitzelsberger; U Kulka; L Lehmann; Axel Walch; Jan Smida; Michaela Aubele; T Lörch; Heinz Höfler; M Bauchinger; Martin Werner
Genetic heterogeneity in a prostatic carcinoma and associated prostatic intraepithelial neoplasia as demonstrated by combined use of laser-microdissection, degenerate oligonucleotide primed PCR and comparative genomic hybridization.
Virchows Archiv : an international journal of pathology 1998;433(4):297-304.
1998: Axel Walch; Horst Zitzelsberger; Michaela Aubele; AE Mattis; M Bauchinger; S Candidus; HW Präuer; Martin Werner; Heinz Höfler
Typical and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization.
The American journal of pathology 1998;153(4):1089-98.
1998: Gregor Weirich; M Sandherr; C Fellbaum; T Richter; L Schmidt; T Kinjerski; H Dietzfelbinger; J Rastetter; Heinz Höfler
Molecular evidence of bone marrow involvement in advanced case ot Tgammadelta lymphoma with secondary myelofibrosis.
Human pathology 1998;29(7):761-5.
1998: Nadia Harbeck; P Dettmar; Christoph Thomssen; B Henselmann; W Kuhn; Kurt Ulm; Fritz Jänicke; Heinz Höfler; Henner Graeff; Manfred Schmitt
Prognostic impact of tumor biological factors on survival in node-negative breast cancer.
Anticancer research 1998;18(3C):2187-97.
1998: Christoph Thomssen; P Oppelt; Fritz Jänicke; Kurt Ulm; Nadia Harbeck; Heinz Höfler; W Kuhn; Henner Graeff; Manfred Schmitt
Identification of low-risk node-negative breast cancer patients by tumor biological factors PAI-1 and cathepsin L.
Anticancer research 1998;18(3C):2173-80.
1998: G Keller; M Rudelius; H Vogelsang; V Grimm; M G Wilhelm; J Mueller; J R Siewert; Heinz Höfler
Microsatellite instability and loss of heterozygosity in gastric carcinoma in comparison to family history.
The American journal of pathology 1998;152(5):1281-9.
1998: Dieter Prechtel; AK Werenskiold; K Prechtel; G Keller; Heinz Höfler
Frequent loss of heterozygosity at chromosome 13q12-13 with BRCA2 markers in sporadic male breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1998;7(1):57-62.
1998: M Hillemanns; S Päsold; K Böttcher; Heinz Höfler
[Prognostic factors of gastrointestinal stromal tumors of the stomach].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1998;82():261-6.
1997: Jörg Rüdiger Siewert; Ulrich Fink; Andreas Sendler; K Becker; Knut Böttcher; H J Feldmann; Heinz Höfler; J Mueller; M Molls; H Nekarda; Jürgen D Roder; Hubert J Stein
Gastric Cancer.
Current problems in surgery 1997;34(11):835-939.
1997: M H Roehrl; Karl-Friedrich Becker; I Becker; Heinz Höfler
Efficiency of single-cell polymerase chain reaction from stained histologic slides and integrity of DNA in archival tissue.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1997;6(5):292-7.
1997: I Becker; K F Becker; M H Röhrl; Heinz Höfler
Laser-assisted preparation of single cells from stained histological slides for gene analysis.
Histochemistry and cell biology 1997;108(4-5):447-51.
1997: J D Mueller; B Pütz; Heinz Höfler
Self-sustained sequence replication (3SR): an alternative to PCR.
Histochemistry and cell biology 1997;108(4-5):431-7.
1997: R Bumm; Hubertus Feussner; H Bartels; H Stein; H J Dittler; Heinz Höfler; Jörg Rüdiger Siewert
Radical transhiatal esophagectomy with two-field lymphadenectomy and endodissection for distal esophageal adenocarcinoma.
World journal of surgery 1997;21(8):822-31.
1997: Gregor Weirich; P Schneider; C Fellbaum; Hiltrud Brauch; W Nathrath; M Scholz; HW Präuer; Heinz Höfler
p53 alterations in thymic epithelial tumours.
Virchows Archiv : an international journal of pathology 1997;431(1):17-23.
1997: Manfred Schmitt; Nadia Harbeck; Christoph Thomssen; Olaf G Wilhelm; Viktor Magdolen; Ute Reuning; Kurt Ulm; Heinz Höfler; Fritz Jänicke; Henner Graeff
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy.
Thrombosis and haemostasis 1997;78(1):285-96.
1997: R Kestlmeier; R Busch; C Fellbaum; K Boettcher; U Reich; J R Siewert; Heinz Höfler
[Incidence and prognostic significance of epithelioid cell reactions and microcarcinoses in regional lymph nodes in stomach carcinoma].
Der Pathologe 1997;18(2):124-30.
1997: J Mueller; E Mueller; E Arras; Birgit Bethke; Manfred Stolte; Heinz Höfler
Stromelysin-3 expression in early (pT1) carcinomas and pseudoinvasive lesions of the colorectum.
Virchows Archiv : an international journal of pathology 1997;430(3):213-9.
1997: I D'Alessandro; Horst Zitzelsberger; Peter Hutzler; L Lehmann; Herbert Braselmann; Sergio Chimenti; Heinz Höfler
Numerical aberrations of chromosome 7 detected in 15 microns paraffin-embedded tissue sections of primary cutaneous melanomas by fluorescence in situ hybridization and confocal laser scanning microscopy.
Journal of cutaneous pathology 1997;24(2):70-5.
1997: Heinz Höfler; A Stier; V Schusdziarra; J R Siewert
[Classification of neuroendocrine tumors of the gastrointestinal tract and pancreas and its therapeutic relevance].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1997;68(2):107-15.
1997: J Böhm; C Fellbaum; Werner Bautz; HW Präuer; Heinz Höfler
Pulmonary nodule caused by an alveolar adenoma of the lung.
Virchows Archiv : an international journal of pathology 1997;430(2):181-4.
1997: Michaela Aubele; Horst Zitzelsberger; S Szücs; Martin Werner; Herbert Braselmann; Peter Hutzler; Karsten Rodenacker; L Lehmann; G Minkus; Heinz Höfler
Comparative FISH analysis of numerical chromosome 7 abnormalities in 5-micron and 15-micron paraffin-embedded tissue sections from prostatic carcinoma.
Histochemistry and cell biology 1997;107(2):121-6.
1997: Heinz Höfler
[Neuroendocrine tumors of the lung].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1997;81():118-24.
1997: Manfred Schmitt; Christoph Thomssen; Kurt Ulm; A Seiderer; Nadia Harbeck; Heinz Höfler; Fritz Jänicke; Henner Graeff
Time-varying prognostic impact of tumour biological factors urokinase (uPA), PAI-1 and steroid hormone receptor status in primary breast cancer.
British journal of cancer 1997;76(3):306-11.
1997: P Dettmar; Nadia Harbeck; Christoph Thomssen; L Pache; P Ziffer; K Fizi; Fritz Jänicke; WB Nathrath; Manfred Schmitt; Henner Graeff; Heinz Höfler
Prognostic impact of proliferation-associated factors MIB1 (Ki-67) and S-phase in node-negative breast cancer.
British journal of cancer 1997;75(10):1525-33.
1996: Ingrid Becker; Karl-Friedrich Becker; M H Röhrl; G Minkus; K Schütze; Heinz Höfler
Single-cell mutation analysis of tumors from stained histologic slides.
Laboratory investigation; a journal of technical methods and pathology 1996;75(6):801-7.
1996: C Reichmuth; M A Markus; M Hillemanns; Michael J Atkinson; K K Unni; G Saretzki; Heinz Höfler
The diagnostic potential of the chromosome translocation t(2;13) in rhabdomyosarcoma: a Pcr study of fresh-frozen and paraffin-embedded tumour samples.
The Journal of pathology 1996;180(1):50-7.
1996: D Glavac; Hartmut P H Neumann; C Wittke; H Jaenig; O Masek; T Streicher; F Pausch; D Engelhardt; K H Plate; Heinz Höfler; F Chen; B Zbar; H Brauch
Mutations in the VHL tumor suppressor gene and associated lesions in families with von Hippel-Lindau disease from central Europe.
Human genetics 1996;98(3):271-80.
1996: Michaela Aubele; G Auer; Heinz Höfler
Analysis of DNA and morphometry in breast carcinoma.
Histochemistry and cell biology 1996;106(2):241-5.
1996: Horst Zitzelsberger; S Szücs; E Robens; Heinz-Ulrich G Weier; Heinz Höfler; M Bauchinger
Combined cytogenetic and molecular genetic analyses of fifty-nine untreated human prostate carcinomas.
Cancer genetics and cytogenetics 1996;90(1):37-44.
1996: Karl-Friedrich Becker; Uli Reich; Gabriele Handschuh; C Dalke; Heinz Höfler
Non-radioactive protein truncation test (nrPTT) for rapid detection of gene mutations.
Trends in genetics : TIG 1996;12(7):250.
1996: Stephan N Wagner; Michael J Atkinson; S Thanner; Manfred Schmitt; O Wilhelm; M Rotter; Heinz Höfler
Type-1 plasminogen activator inhibitor in human renal cell carcinoma.
The Journal of pathology 1996;179(1):95-9.
1996: J Böhm; S Koch; Peter Gais; Uta Jütting; HW Präuer; Heinz Höfler
Prognostic value of MIB-1 in neuroendocrine tumours of the lung.
The Journal of pathology 1996;178(4):402-9.
1996: H P Niedermeyer; K Peris; Heinz Höfler
Pilomatrix carcinoma with multiple visceral metastases. Report of a case.
Cancer 1996;77(7):1311-4.
1996: Stephan N Wagner; Michael J Atkinson; C Wagner; Heinz Höfler; Manfred Schmitt; O Wilhelm
Sites of urokinase-type plasminogen activator expression and distribution of its receptor in the normal human kidney.
Histochemistry and cell biology 1996;105(1):53-60.
1996: S Candidus; P Bischoff; Karl-Friedrich Becker; Heinz Höfler
No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas.
Cancer research 1996;56(1):49-52.
1995: Karl-Friedrich Becker; Uli Reich; Christina Schott; Heinz Höfler
Single nucleotide polymorphisms in the human E-cadherin gene.
Human genetics 1995;96(6):739-40.
1995: Arnulf H Hölscher; Elfriede Bollschweiler; R Bumm; H Bartels; Heinz Höfler; Jörg Rüdiger Siewert
Prognostic factors of resected adenocarcinoma of the esophagus.
Surgery 1995;118(5):845-55.
1995: Ketty Peris; G Keller; Sergio Chimenti; A Amantea; Helmut Kerl; Heinz Höfler
Microsatellite instability and loss of heterozygosity in melanoma.
The Journal of investigative dermatology 1995;105(4):625-8.
1995: Heinz Höfler; B Pütz; J D Mueller; W Neubert; G Sutter; Peter Gais
In situ amplification of measles virus RNA by the self-sustained sequence replication reaction.
Laboratory investigation; a journal of technical methods and pathology 1995;73(4):577-85.
1995: Barbara Schmalfeldt; W Kuhn; Ute Reuning; L Pache; P Dettmar; Manfred Schmitt; Fritz Jänicke; Heinz Höfler; Henner Graeff
Primary tumor and metastasis in ovarian cancer differ in their content of urokinase-type plasminogen activator, its receptor, and inhibitors types 1 and 2.
Cancer research 1995;55(18):3958-63.
1995: G Keller; M Rotter; H Vogelsang; P Bischoff; Karl-Friedrich Becker; J Mueller; H Brauch; J R Siewert; Heinz Höfler
Microsatellite instability in adenocarcinomas of the upper gastrointestinal tract. Relation to clinicopathological data and family history.
The American journal of pathology 1995;147(3):593-600.
1995: Stephan N Wagner; C Wagner; Heinz Höfler; M J Atkinson; M Goos
Expression cloning of the cDNA encoding a melanoma-associated Ag recognized by mAb HMB-45. Identification as melanocyte-specific Pmel 17 cDNA.
Laboratory investigation; a journal of technical methods and pathology 1995;73(2):229-35.
1995: Andreas Sendler; H J Dittler; Hubertus Feussner; H Nekarda; Elfriede Bollschweiler; Ulrich Fink; Hermann Helmberger; Heinz Höfler; Jörg Rüdiger Siewert
Preoperative staging of gastric cancer as precondition for multimodal treatment.
World journal of surgery 1995;19(4):501-8.
1995: Stephan N Wagner; Michael J Atkinson; S Thanner; C Wagner; Manfred Schmitt; O Wilhelm; M Rotter; Heinz Höfler
Modulation of urokinase and urokinase receptor gene expression in human renal cell carcinoma.
The American journal of pathology 1995;147(1):183-92.
1995: H Brauch; T Kishida; D Glavac; F Chen; F Pausch; Heinz Höfler; F Latif; M I Lerman; B Zbar; Hartmut P H Neumann
Von Hippel-Lindau (VHL) disease with pheochromocytoma in the Black Forest region of Germany: evidence for a founder effect.
Human genetics 1995;95(5):551-6.
1995: Stephan N Wagner; H M Ockenfels; C Wagner; Heinz Höfler; M Goos
Ras gene mutations: a rare event in nonmetastatic primary malignant melanoma.
The Journal of investigative dermatology 1995;104(5):868-71.
1995: Gregor Weirich; A Funk; I Hoepner; U Heider; S Noll; B Pütz; C Fellbaum; Heinz Höfler
PCR-based assays for the detection of monoclonality in non-Hodgkin's lymphoma: application to formalin-fixed, paraffin-embedded tissue and decalcified bone marrow samples.
Journal of molecular medicine (Berlin, Germany) 1995;73(5):235-41.
1995: Jörg Rüdiger Siewert; Andreas Sendler; H J Dittler; Ulrich Fink; Heinz Höfler
Staging gastrointestinal cancer as a precondition for multimodal treatment.
World journal of surgery 1995;19(2):168-77.
1994: S Szücs; Horst Zitzelsberger; J Breul; M Bauchinger; Heinz Höfler
Two-phase short-term culture method for cytogenetic investigations from human prostate carcinoma.
The Prostate 1994;25(5):225-35.
1994: Karl-Friedrich Becker; M J Atkinson; Uli Reich; I Becker; H Nekarda; Jörg Rüdiger Siewert; Heinz Höfler
E-cadherin gene mutations provide clues to diffuse type gastric carcinomas.
Cancer research 1994;54(14):3845-52.
1994: Horst Zitzelsberger; S Szücs; Heinz-Ulrich G Weier; L Lehmann; Herbert Braselmann; S Enders; A Schilling; J Breul; Heinz Höfler; M Bauchinger
Numerical abnormalities of chromosome 7 in human prostate cancer detected by fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with centromere-specific DNA probes.
The Journal of pathology 1994;172(4):325-35.
1994: Heinz Höfler
[Prognostic factors in pancreatic cancer].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1994;65(4):253-7.
1994: U Heinzmann; Heinz Höfler
Detection of epidermal growth factor receptor by scanning electron microscopy.
Histochemistry 1994;101(2):127-34.
1994: A Funk; J Rudel; C Fellbaum; Heinz Höfler
[Specific in situ labeling of apoptosis shows different rates of programmed cell death in non-Hodgkin lymphomas].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():318-20.
1994: Ketty Peris; H Niedermeyer; L Cerroni; T Radaskiewicz; Sergio Chimenti; Heinz Höfler
Detection of Epstein-Barr virus genome in primary cutaneous T and B cell lymphomas and pseudolymphomas.
Archives of dermatological research 1994;286(7):364-8.
1994: K Kunth; Heinz Höfler; M J Atkinson
[Quantification of messenger RNA expression in tumors: which standard should be used for best RNA normalization?].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():226-30.
1994: Heinz Höfler; J Mueller
In situ hybridization in pathology.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():124-35.
1993: Dietmar R Lohmann; B Fesseler; B Pütz; U Reich; J Böhm; HW Präuer; P H Wünsch; Heinz Höfler
Infrequent mutations of the p53 gene in pulmonary carcinoid tumors.
Cancer research 1993;53(23):5797-801.
1993: Karl-Friedrich Becker; Michael J Atkinson; Uli Reich; H H Huang; H Nekarda; J R Siewert; Heinz Höfler
Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas.
Human molecular genetics 1993;2(6):803-4.
1993: D Lohmann; B Pütz; U Reich; J Böhm; HW Präuer; Heinz Höfler
Mutational spectrum of the p53 gene in human small-cell lung cancer and relationship to clinicopathological data.
The American journal of pathology 1993;142(3):907-15.
1993: D Lohmann; C Ruhri; M Schmitt; H Graeff; Heinz Höfler
Accumulation of p53 protein as an indicator for p53 gene mutation in breast cancer. Occurrence of false-positives and false-negatives.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1993;2(1):36-41.
1993: Fritz Jänicke; M Schmitt; L Pache; Kurt Ulm; Nadia Harbeck; Heinz Höfler; Henner Graeff
Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer.
Breast cancer research and treatment 1993;24(3):195-208.
1993: J Böhm; V Kacic; Peter Gais; HW Präuer; Heinz Höfler
Prognostic value of nucleolar organizer regions in neuroendocrine tumours of the lung.
Histochemistry 1993;99(1):85-90.
1993: Dietmar R Lohmann; A Funk; H P Niedermeyer; S Häupel; Heinz Höfler
Identification of p53 gene mutations in gastrointestinal and pancreatic carcinoids by nonradioisotopic SSCA.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;64(5):293-6.
1993: Nadia Harbeck; E Schüren; N Yamamoto; L Pache; Manfred Schmitt; Fritz Jänicke; P Dettmar; Heinz Höfler; Henner Graeff
[DNA flow cytometric analysis in primary breast cancer. S-phase and ploidy status as prognostic factors and their correlation to tumor-associated proteolytic factors].
Gynäkologisch-geburtshilfliche Rundschau 1993;33 Suppl 1():303-4.
1993: Nadia Harbeck; E Schüren; N Yamamoto; Manfred Schmitt; Heinz Höfler; Henner Graeff
[Development of a technique for isolation of intact tumor cells from fresh breast or ovarian cancer tissue. Use in analysis of tumor-associated proteolytic factors].
Gynäkologisch-geburtshilfliche Rundschau 1993;33 Suppl 1():277-9.
1993: Stephan N Wagner; R Müller; J Boehm; B Pütz; P H Wünsch; Heinz Höfler
Neuroendocrine neoplasms of the lung are not associated with point mutations at codon 12 of the Ki-ras gene.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;63(5):325-9.
1993: S Szücs; Horst Zitzelsberger; M Roter; M Bauchinger; Heinz Höfler
[Cytogenetic investigations in primary prostate carcinomas].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1993;77():138-41.
1992: M Rotter; T Block; R Busch; S Thanner; Heinz Höfler
Expression of HER-2/neu in renal-cell carcinoma. Correlation with histologic subtypes and differentiation.
International journal of cancer. Journal international du cancer 1992;52(2):213-7.
1992: Stephan N Wagner; C Ruhri; K Kunth; B U Holecek; M Goos; Heinz Höfler; Michael J Atkinson
Expression of stromelysin 3 in the stromal elements of human basal cell carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1992;1(3):200-5.
1992: D Lohmann; B Horsthemke; Gabriele Gillessen-Kaesbach; F H Stefani; Heinz Höfler
Detection of small RB1 gene deletions in retinoblastoma by multiplex PCR and high-resolution gel electrophoresis.
Human genetics 1992;89(1):49-53.
1992: P G Strauss; K Mitreiter; Horst Zitzelsberger; A Luz; Jörg Schmidt; Volker Erfle; Heinz Höfler
Elevated p53 RNA expression correlates with incomplete osteogenic differentiation of radiation-induced murine osteosarcomas.
International journal of cancer. Journal international du cancer 1992;50(2):252-8.
1992: Gernot Wirnsberger; H Becker; K Ziervogel; Heinz Höfler
Diagnostic immunohistochemistry of neuroblastic tumors.
The American journal of surgical pathology 1992;16(1):49-57.
1992: U Heinzmann; Heinz Höfler
EGF-receptor immunolabeling as shown by LM and SEM.
Progress in histochemistry and cytochemistry 1992;26(1-4):88-94.
1992: C Fellbaum; T Radaszkiewicz; C Ruhri; B Pütz; W Lehmacher; Heinz Höfler
c-myc mRNA expression in non-Hodgkin's lymphomas.
Virchows Archiv. B, Cell pathology including molecular pathology 1992;62(1):61-8.
1992: D Rohde; H Niedermeyer; C Fellbaum; Martin-Leo Hansmann; Raymonde Busch; I Lauder; Heinz Höfler; R Fischer
[Nodular paragranuloma and Epstein-Barr virus: frequency of EBV DNA and clinical relevance].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1992;76():177-80.
1992: H Niedermeyer; C Fellbaum; Martin-Leo Hansmann; I Kraus; M J Alavaikko; Raymonde Busch; B Pütz; R Fischer; Heinz Höfler
[Influence of Epstein-Barr virus genome on patient survival in Hodgkin's disease].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1992;76():173-6.
1991: J Böhm; M Röder-Weber; Heinz Höfler; M Kolben
Bilateral stromal Leydig cell tumour of the ovary. Case report and literature review.
Pathology, research and practice 1991;187(2-3):348-52; discussion 352-3.
1991: Ketty Peris; L Cerroni; Sergio Chimenti; Hans Peter Soyer; Helmut Kerl; Heinz Höfler
Proto-oncogene expression in dermal naevi and melanomas.
Archives of dermatological research 1991;283(8):500-5.
1990: M Kolben; Fritz Jänicke; J Böhm; M Röder-Weber; H Graeff; Heinz Höfler
[Androgenization in postmenopause in rare ovarian tumors--2 case reports].
Geburtshilfe und Frauenheilkunde 1990;50(8):650-2.
1990: Roswitha Pfragner; Heinz Höfler; Annemarie Behmel; E Ingolic; V Walser
Establishment and characterization of continuous cell line MTC-SK derived from a human medullary thyroid carcinoma.
Cancer research 1990;50(13):4160-6.
1990: A Pagani; M Papotti; Heinz Höfler; R Weiler; H Winkler; G Bussolati
Chromogranin A and B gene expression in carcinomas of the breast. Correlation of immunocytochemical, immunoblot, and hybridization analyses.
The American journal of pathology 1990;136(2):319-27.
1990: H Becker; Gernot Wirnsberger; K Ziervogel; Heinz Höfler
Immunohistochemical markers in (ganglio)neuroblastomas.
Acta histochemica. Supplementband 1990;38():107-14.
1990: M Klimpfinger; G Zisser; C Ruhri; B Pütz; Peter Steindorfer; Heinz Höfler
Expression of c-myc and c-fos mRNA in colorectal carcinoma in man.
Virchows Archiv. B, Cell pathology including molecular pathology 1990;59(3):165-71.
1990: Heinz Höfler
[Oncogenes and oncogene products--possibilities and significance of their detection].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():319-27.
1989: Heinz Höfler; H J Wolfe
mRNA detection by in situ hybridization with radioactive probes.
Acta histochemica. Supplementband 1989;37():79-82.
1988: Heinz Höfler; Gernot Wirnsberger; B Pütz; C Ruhri
Histochemical demonstration of lectin binding sites in neuroendocrine tumors.
Acta histochemica. Supplementband 1988;36():273-6.
1988: Heinz Höfler; C Ruhri; B Pütz; Gernot Wirnsberger; H Hauser
Oncogene expression in endocrine pancreatic tumors.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;55(6):355-61.
1988: M Klimpfinger; C Ruhri; B Pütz; Roswitha Pfragner; Gernot Wirnsberger; Heinz Höfler
Oncogene expression in a medullary thyroid carcinoma.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;54(4):256-9.
1987: Heinz Höfler; C Ruhri; B Pütz; Gernot Wirnsberger
[Oncogene expression in endocrine pancreatic tumors].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1987;71():306-10.
1987: Heinz Höfler; B Pütz; C Ruhri; Gernot Wirnsberger; M Klimpfinger; J Smolle
Simultaneous localization of calcitonin mRNA and peptide in a medullary thyroid carcinoma.
Virchows Archiv. B, Cell pathology including molecular pathology 1987;54(3):144-51.