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Heinz Höfler

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Keller Gisela; Geist Birgit; Slotta-Huspenina Julia; Langer Rupert; Nagl Florian; Fend Falko; Höfler Heinz; Perren Aurel
Novel multiple, monoallelic KRAS mutations at codon 12 and 13.
Aubele Michaela; Vidojkovic Sanja; Braselmann Herbert; Ritterswürden Dominique; Auer Gert; Atkinson Mike J; Tapio Soile; Höfler Heinz; Rauser Sandra; Bartlett John M S
Overexpression of PTK6 (breast tumor kinase) protein--a prognostic factor for long-term breast cancer survival--is not due to gene amplification.
Schulz Daniela M; Böllner Claudia; Thomas Gerry; Atkinson Mike; Esposito Irene; Höfler Heinz; Aubele Michaela
Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry.

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All Publications

2009: Keller Gisela; Geist Birgit; Slotta-Huspenina Julia; Langer Rupert; Nagl Florian; Fend Falko; Höfler Heinz; Perren Aurel
Novel multiple, monoallelic KRAS mutations at codon 12 and 13.
International journal of cancer. Journal international du cancer 2009;125(11):2744-5.
2009: Aubele Michaela; Vidojkovic Sanja; Braselmann Herbert; Ritterswürden Dominique; Auer Gert; Atkinson Mike J; Tapio Soile; Höfler Heinz; Rauser Sandra; Bartlett John M S
Overexpression of PTK6 (breast tumor kinase) protein--a prognostic factor for long-term breast cancer survival--is not due to gene amplification.
Virchows Archiv : an international journal of pathology 2009;455(2):117-23.
2009: Schulz Daniela M; Böllner Claudia; Thomas Gerry; Atkinson Mike; Esposito Irene; Höfler Heinz; Aubele Michaela
Identification of differentially expressed proteins in triple-negative breast carcinomas using DIGE and mass spectrometry.
Journal of proteome research 2009;8(7):3430-8.
2009: Kojc Nika; Zidar Nina; Gale Nina; Poljak Mario; Fujs Komlos Kristina; Cardesa Antonio; Höfler Heinz; Becker Karl-Friedrich
Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck.
Virchows Archiv : an international journal of pathology 2009;454(5):549-55.
2009: Wiech Thorsten; Nikolopoulos Elisabeth; Weis Roland; Langer Rupert; Bartholomé Kilian; Timmer Jens; Walch Axel K; Höfler Heinz; Werner Martin
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays.
Laboratory investigation; a journal of technical methods and pathology 2009;89(4):385-97.
2009: Herrmann Ken; Walch Axel; Balluff Benjamin; Tänzer Marc; Höfler Heinz; Krause Bernd J; Schwaiger Markus; Friess Helmut; Schmid Roland M; Ebert Matthias P A
Proteomic and metabolic prediction of response to therapy in gastrointestinal cancers.
Nature clinical practice. Gastroenterology & hepatology 2009;6(3):170-83.
2009: Brücher Björn L D M; Keller Gisela; Werner Martin; Müller Ulrike; Lassmann Silke; Cabras Antonello Domenico; Fend Falko; Busch Raymonde; Stein Hubert; Allescher Hans-Dieter; Molls Michael; Siewert J Rüdiger; Höfler Heinz; Specht Katja
Using Q-RT-PCR to measure cyclin D1, TS, TP, DPD, and Her-2/neu as predictors for response, survival, and recurrence in patients with esophageal squamous cell carcinoma following radiochemotherapy.
International journal of colorectal disease 2009;24(1):69-77.
2009: Voland Petra; Besig Sophie; Rad Roland; Braun Thomas; Baur Dorothee M; Perren Aurel; Langer Rupert; Höfler Heinz; Prinz Christian
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Neuroendocrinology 2009;89(1):66-78.
2008: Lorenzen S; Brücher B; Zimmermann F; Geinitz H; Riera J; Schuster T; Roethling N; Höfler H; Ott K; Peschel C; Siewert J R; Molls M; Lordick F
Neoadjuvant continuous infusion of weekly 5-fluorouracil and escalating doses of oxaliplatin plus concurrent radiation in locally advanced oesophageal squamous cell carcinoma: results of a phase I/II trial.
British journal of cancer 2008;99(7):1020-6.
2008: Zidar Nina; Gale Nina; Kojc Nika; Volavsek Metka; Cardesa Antonio; Alos Llucia; Höfler Heinz; Blechschmidt Kareen; Becker Karl-Friedrich
Cadherin-catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck.
Virchows Archiv : an international journal of pathology 2008;453(3):267-74.
2008: Walch Axel; Rauser Sandra; Deininger Sören-Oliver; Höfler Heinz
MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology.
Histochemistry and cell biology 2008;130(3):421-34.
2008: Ott Katja; Lordick Florian; Becker Karen; Ulm Kurt; Siewert JörgRüdiger; Höfler Heinz; Keller Gisela
Glutathione-S-transferase P1, T1 and M1 genetic polymorphisms in neoadjuvant-treated locally advanced gastric cancer: GSTM1-present genotype is associated with better prognosis in completely resected patients.
International journal of colorectal disease 2008;23(8):773-82.
2008: Bamba Masamichi; Sugihara Hiroyuki; Becker Karl-Friedrich; Becker Ingrid; Höfler Heinz; Hattori Takanori
A case of multiple diffuse gastric carcinoma with regional expression of mutant E-cadherin.
Virchows Archiv : an international journal of pathology 2008;452(5):581-3.
2008: Walch Axel; Seidl Stefan; Hermannstädter Christine; Rauser Sandra; Deplazes Joëlle; Langer Rupert; von Weyhern Claus Hann; Sarbia Mario; Busch Raymonde; Feith Marcus; Gillen Sonja; Höfler Heinz; Luber Birgit
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(5):544-52.
2008: Bremm Anja; Walch Axel; Fuchs Margit; Mages Jörg; Duyster Justus; Keller Gisela; Hermannstädter Christine; Becker Karl-Friedrich; Rauser Sandra; Langer Rupert; von Weyhern Claus Hann; Höfler Heinz; Luber Birgit
Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations.
Cancer research 2008;68(3):707-14.
2008: Blechschmidt K; Sassen S; Schmalfeldt B; Schuster T; Höfler H; Becker K-F
The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients.
British journal of cancer 2008;98(2):489-95.
2008: Fuchs Margit; Hermannstädter Christine; Hutzler Peter; Häcker Georg; Haller Ferdinand; Höfler Heinz; Luber Birgit
Deletion of exon 8 increases cisplatin-induced E-cadherin cleavage.
Experimental cell research 2008;314(1):153-63.
2008: Hipp Susanne; Walch Axel; Schuster Tibor; Höfler Heinz; Becker Karl-Friedrich
Precise measurement of the E-cadherin repressor Snail in formalin-fixed endometrial carcinoma using protein lysate microarrays.
Clinical & experimental metastasis 2008;25(6):679-83.
2007: Blechschmidt Kareen; Kremmer Elisabeth; Hollweck Regina; Mylonas Ioannis; Höfler Heinz; Kremer Marcus; Becker Karl-Friedrich
The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2007;16(4):222-8.
2007: Rauser Sandra; Weis Roland; Braselmann Herbert; Feith Marcus; Stein Hubert J; Langer Rupert; Hutzler Peter; Hausmann Michael; Lassmann Silke; Siewert Jörg Rüdiger; Höfler Heinz; Werner Martin; Walch Axel
Significance of HER2 low-level copy gain in Barrett's cancer: implications for fluorescence in situ hybridization testing in tissues.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(17):5115-23.
2007: Langer Rupert; Specht Katja; Becker Karen; Ewald Philipp; Ott Katja; Lordick Florian; Siewert Jörg-Rüdiger; Höfler Heinz
Comparison of pretherapeutic and posttherapeutic expression levels of chemotherapy-associated genes in adenocarcinomas of the esophagus treated by 5-fluorouracil- and cisplatin-based neoadjuvant chemotherapy.
American journal of clinical pathology 2007;128(2):191-7.
2007: Pellegata Natalia S; Quintanilla-Martinez Leticia; Keller Gisela; Liyanarachchi Sandya; Höfler Heinz; Atkinson Michael J; Fend Falko
Human pheochromocytomas show reduced p27Kip1 expression that is not associated with somatic gene mutations and rarely with deletions.
Virchows Archiv : an international journal of pathology 2007;451(1):37-46.
2007: Gamboa-Dominguez Armando; Seidl Stefan; Reyes-Gutierrez Edgardo; Hermannstädter Christine; Quintanilla-Martinez Leticia; Busch Raymonde; Höfler Heinz; Fend Falko; Luber Birgit
Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer.
Journal of clinical pathology 2007;60(7):756-61.
2007: Becker K-F; Schott C; Hipp S; Metzger V; Porschewski P; Beck R; Nährig J; Becker I; Höfler H
Quantitative protein analysis from formalin-fixed tissues: implications for translational clinical research and nanoscale molecular diagnosis.
The Journal of pathology 2007;211(3):370-8.
2007: Wiese Anja H; Auer Johannes; Lassmann Silke; Nährig Jörg; Rosenberg Robert; Höfler Heinz; Rüger Rüdiger; Werner Martin
Identification of gene signatures for invasive colorectal tumor cells.
Cancer detection and prevention 2007;31(4):282-95.
2007: Höfler Heinz; Langer Rupert; Ott Katja; Keller Gisela
Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2007;176():33-6.
2007: Becker K-F; Rosivatz E; Blechschmidt K; Kremmer E; Sarbia M; Höfler H
Analysis of the E-cadherin repressor Snail in primary human cancers.
Cells, tissues, organs 2007;185(1-3):204-12.
2007: Kunder Sandra; Calzada-Wack Julia; Hölzlwimmer Gabriele; Müller Jacqueline; Kloss Claudia; Howat Will; Schmidt Jörg; Höfler Heinz; Warren Madhuri; Quintanilla-Martinez Leticia
A comprehensive antibody panel for immunohistochemical analysis of formalin-fixed, paraffin-embedded hematopoietic neoplasms of mice: analysis of mouse specific and human antibodies cross-reactive with murine tissue.
Toxicologic pathology 2007;35(3):366-75.
2006: Ott Katja; Vogelsang Holger; Marton Noemi; Becker Karen; Lordick Florian; Kobl Michael; Schuhmacher Christoph; Novotny Alexander; Mueller James; Fink Ulrich; Ulm Kurt; Siewert Jörg Rüdiger; Höfler Heinz; Keller Gisela
The thymidylate synthase tandem repeat promoter polymorphism: A predictor for tumor-related survival in neoadjuvant treated locally advanced gastric cancer.
International journal of cancer. Journal international du cancer 2006;119(12):2885-94.
2006: Pellegata Natalia S; Quintanilla-Martinez Leticia; Siggelkow Heide; Samson Elenore; Bink Karin; Höfler Heinz; Fend Falko; Graw Jochen; Atkinson Michael J
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(42):15558-63.
2006: Reiter Rudolf; Gais Peter; Jütting Uta; Steuer-Vogt Miriam K; Pickhard Anja; Bink Karin; Rauser Sandra; Lassmann Silke; Höfler Heinz; Werner Martin; Walch Axel
Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5136-41.
2006: Nährig J; Höfler H; Heywang-Köbrunner S H; Prat N; Hölzel D; Wünsch P H; Lebeau A
[Experiences of the Bavarian mammography screening program]
Der Pathologe 2006;27(5):387-91.
2006: Fargnoli Maria Concetta; Altobelli Emma; Keller Gisela; Chimenti Sergio; Höfler Heinz; Peris Ketty
Contribution of melanocortin-1 receptor gene variants to sporadic cutaneous melanoma risk in a population in central Italy: a case-control study.
Melanoma research 2006;16(2):175-82.
2006: Lassmann Silke; Hennig Michael; Rosenberg Robert; Nährig Jörg; Schreglmann Joachim; Krause Friedemann; Poignee-Heger Manuela; Nekarda Hjalmar; Höfler Heinz; Werner Martin
Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-up.
International journal of colorectal disease 2006;21(3):238-47.
2006: Rosivatz Erika; Becker Karl-Friedrich; Kremmer Elisabeth; Schott Christina; Blechschmidt Kareen; Höfler Heinz; Sarbia Mario
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract.
Virchows Archiv : an international journal of pathology 2006;448(3):277-87.
2006: Höfler H
[Role of pathology: tumour banks, quality of tissue and more?]
Verhandlungen der Deutschen Gesellschaft für Pathologie 2006;90():46-51.
2005: Langer Rupert; Specht Katja; Becker Karen; Ewald Philipp; Bekesch Melitta; Sarbia Mario; Busch Raymonde; Feith Marcus; Stein Hubert J; Siewert Jörg-Rüdiger; Höfler Heinz
Association of pretherapeutic expression of chemotherapy-related genes with response to neoadjuvant chemotherapy in Barrett carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7462-9.
2005: Biedermann Karin; Vogelsang Holger; Becker Ingrid; Plaschke Susanne; Siewert Jörg Rüdiger; Höfler Heinz; Keller Gisela
Desmoglein 2 is expressed abnormally rather than mutated in familial and sporadic gastric cancer.
The Journal of pathology 2005;207(2):199-206.
2005: Keller Gisela; Höfler Heinz; Becker Karl-Friedrich
Molecular medicine of gastric adenocarcinomas.
Expert reviews in molecular medicine 2005;7(17):1-13.
2005: Fuchs Margit; Hermannstädter Christine; Specht Katja; Knyazev Pjotr; Ullrich Axel; Rosivatz Erika; Busch Raymonde; Hutzler Peter; Höfler Heinz; Luber Birgit
Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3.
Journal of cellular physiology 2005;202(3):805-13.
2005: Schulz Stephan; Cabras Antonello Domenico; Kremer Marcus; Weirich Gregor; Miethke Thomas; Bösmüller Hans-Christian; Höfler Heinz; Werner Martin; Fend Falko
Species identification of mycobacteria in paraffin-embedded tissues: frequent detection of nontuberculous mycobacteria.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(2):274-82.
2005: Gamboa-Dominguez Armando; Dominguez-Fonseca Claudia; Chavarri-Guerra Yanin; Vargas Roberto; Reyes-Gutierrez Edgardo; Green Dan; Quintanilla-Martinez Leticia; Luber Birgit; Busch Raymonde; Becker Karl-Friedrich; Becker Ingrid; Höfler Heinz; Fend Falko
E-cadherin expression in sporadic gastric cancer from Mexico: exon 8 and 9 deletions are infrequent events associated with poor survival.
Human pathology 2005;36(1):29-35.
2004: Walch Axel; Specht Katja; Braselmann Herbert; Stein Hubert; Siewert Jörg Rüdiger; Hopt Ulrich; Höfler Heinz; Werner Martin
Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinoma.
International journal of cancer. Journal international du cancer 2004;112(5):747-53.
2004: Fuchs Margit; Hutzler Peter; Handschuh Gabriele; Hermannstädter Christine; Brunner Ingrid; Höfler Heinz; Luber Birgit
Dynamics of cell adhesion and motility in living cells is altered by a single amino acid change in E-cadherin fused to enhanced green fluorescent protein.
Cell motility and the cytoskeleton 2004;59(1):50-61.
2004: Rosivatz Erika; Becker Ingrid; Bamba Masamichi; Schott Christina; Diebold Joachim; Mayr Doris; Höfler Heinz; Becker Karl-Friedrich
Neoexpression of N-cadherin in E-cadherin positive colon cancers.
International journal of cancer. Journal international du cancer 2004;111(5):711-9.
2004: Sarbia Mario; Becker Karl Friedrich; Höfler Heinz
Pathology of upper gastrointestinal malignancies.
Seminars in oncology 2004;31(4):465-75.
2004: Albrecht Bettina; Hausmann Michael; Zitzelsberger Horst; Stein Hubert; Siewert Jörg Rüdiger; Hopt Ulrich; Langer Rupert; Höfler Heinz; Werner Martin; Walch Axel
Array-based comparative genomic hybridization for the detection of DNA sequence copy number changes in Barrett's adenocarcinoma.
The Journal of pathology 2004;203(3):780-8.
2004: Keller G; Vogelsang H; Becker I; Plaschke S; Ott K; Suriano G; Mateus A R; Seruca R; Biedermann K; Huntsman D; Döring C; Holinski-Feder E; Neutzling A; Siewert J R; Höfler H
Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients.
Journal of medical genetics 2004;41(6):e89.
2004: Gamboa-Dominguez Armando; Dominguez-Fonseca Claudia; Quintanilla-Martinez Leticia; Reyes-Gutierrez Edgardo; Green Dan; Angeles-Angeles Arturo; Busch Raymonde; Hermannstädter Christine; Nährig Jörg; Becker Karl-Friedrich; Becker Ingrid; Höfler Heinz; Fend Falko; Luber Birgit
Epidermal growth factor receptor expression correlates with poor survival in gastric adenocarcinoma from Mexican patients: a multivariate analysis using a standardized immunohistochemical detection system.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(5):579-87.
2004: Lassmann S; Bauer M; Rosenberg R; Nekarda H; Soong R; Rüger R; Höfler H; Werner M
Identification of occult tumor cells in node negative lymph nodes of colorectal cancer patients by cytokeratin 20 gene and protein expression.
International journal of colorectal disease 2004;19(2):87-94.
2004: Langer R; Specht K; Becker K; Ewald P; Sarbia M; Busch R; Feith M; Stein H J; Siewert J R; Höfler H
[Prediction of response to neoadjuvant chemotherapy in Barrett's carcinoma by quantitative gene expression analysis]
Verhandlungen der Deutschen Gesellschaft für Pathologie 2004;88():207-13.
2004: Fricke Elena; Hermannstädter Christine; Keller Gisela; Fuchs Margit; Brunner Ingrid; Busch Raymonde; Höfler Heinz; Becker Karl-Friedrich; Luber Birgit
Effect of wild-type and mutant E-cadherin on cell proliferation and responsiveness to the chemotherapeutic agents cisplatin, etoposide, and 5-fluorouracil.
Oncology 2004;66(2):150-9.
2003: Kremer Marcus; Quintanilla-Martinez Leticia; Fuchs Margit; Gamboa-Dominguez Armando; Haye Sieglinde; Kalthoff Holger; Rosivatz Erika; Hermannstädter Christine; Busch Raymonde; Höfler Heinz; Luber Birgit
Influence of tumor-associated E-cadherin mutations on tumorigenicity and metastasis.
Carcinogenesis 2003;24(12):1879-86.
2003: Becker Karen; Mueller James D; Schulmacher Christoph; Ott Katja; Fink Ulrich; Busch Raymonde; Böttcher Knut; Siewert J Rüdiger; Höfler Heinz
Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy.
Cancer 2003;98(7):1521-30.
2003: Stein H J; von Rahden B H A; Höfler H; Siewert J R
[Carcinoma of the oesophagogastric junction and Barrett's esophagus: an almost clear oncologic model?]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2003;74(8):703-8.
2003: Hapke Sandra; Kessler Horst; Luber Birgit; Benge Anke; Hutzler Peter; Höfler Heinz; Schmitt Manfred; Reuning Ute
Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/Vitronectin interaction.
Biological chemistry 2003;384(7):1073-83.
2003: Nährig Jörg M; Richter Thomas; Kuhn Walther; Avril Norbert; Flatau Birgit; Kowolik Jurgen; Höfler Heinz; Werner Martin
Intraoperative examination of sentinel lymph nodes by ultrarapid immunohistochemistry.
The breast journal 2003;9(4):277-81.
2003: Fargnoli Maria Concetta; Chimenti Sergio; Keller Gisela; Höfler Heinz; Peris Ketty
Identification of four novel melanocortin 1 receptor (MC1R) gene variants in a Mediterranean population.
Human mutation 2003;21(6):655.
2003: Ott Katja; Vogelsang Holger; Mueller James; Becker Karen; Müller Martina; Fink Ulrich; Siewert Jörg Rüdiger; Höfler Heinz; Keller Gisela
Chromosomal instability rather than p53 mutation is associated with response to neoadjuvant cisplatin-based chemotherapy in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2307-15.
2003: Quintanilla-Martinez Leticia; Kremer Marcus; Specht Katja; Calzada-Wack Julia; Nathrath Michaela; Schaich Robert; Höfler Heinz; Fend Falko
Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat 3 activation and cyclin D1 dysregulation are mutually exclusive events.
The American journal of pathology 2003;162(5):1449-61.
2003: Zemzoum Iris; Kates Ronald E; Ross Jeffrey S; Dettmar Peer; Dutta Moshumi; Henrichs Cordula; Yurdseven Suna; Höfler Heinz; Kiechle Marion; Schmitt Manfred; Harbeck Nadia
Invasion factors uPA/PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(6):1022-8.
2003: Weirich Gregor; Nährig Jörg; Treiber Uwe; Hartmann Carmen; Hartung Rudolf; Höfler Heinz; Fend Falko
Immunohistochemical assessment of a testicular tumor in a 63-year-old patient: proposal for an integrated clinicopathologic approach.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2003;11(1):96-100.
2003: Fricke Elena; Keller Gisela; Becker Ingrid; Rosivatz Erika; Schott Christina; Plaschke Susanne; Rudelius Martina; Hermannstädter Christine; Busch Raymonde; Höfler Heinz; Becker Karl-Friedrich; Luber Birgit
Relationship between E-cadherin gene mutation and p53 gene mutation, p53 accumulation, Bcl-2 expression and Ki-67 staining in diffuse-type gastric carcinoma.
International journal of cancer. Journal international du cancer 2003;104(1):60-5.
2003: Morelli Luca; Pusiol Teresa; Piscioli Francesco; Höfler Heinz; Weirich Gregor; Werner Martin; Cabras Antonello Domenico
Herpesvirus 8-associated penile Kaposi's sarcoma in an HIV-negative patient: first report of a solitary lesion.
The American Journal of dermatopathology 2003;25(1):28-31.
2003: Höfler H; Becker K F; Keller G
[Molecular carcinogenesis of the upper gastrointestinal tract]
Verhandlungen der Deutschen Gesellschaft für Pathologie 2003;87():123-9.
2003: Höfler Heinz; Specht Katja; Becker Karl-Friedrich
Molecular analysis of gene expression in tumor pathology.
Advances in experimental medicine and biology 2003;532():19-26.
2002: Rosivatz Erika; Becker Ingrid; Specht Katja; Fricke Elena; Luber Birgit; Busch Raymonde; Höfler Heinz; Becker Karl-Friedrich
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.
The American journal of pathology 2002;161(5):1881-91.
2002: Lassmann Silke; Bauer Markus; Soong Richie; Schreglmann Joachim; Tabiti Karim; Nährig Jörg; Rüger Rüdiger; Höfler Heinz; Werner Martin
Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity.
The Journal of pathology 2002;198(2):198-206.
2002: Specht Katja; Kremer Marcus; Müller Ulrike; Dirnhofer Stephan; Rosemann Michael; Höfler Heinz; Quintanilla-Martinez Leticia; Fend Falko
Identification of cyclin D1 mRNA overexpression in B-cell neoplasias by real-time reverse transcription-PCR of microdissected paraffin sections.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2902-11.
2002: Weirich Gregor; Cabras Antonello D; Serra Stefano; Coni Pier P; Nurchi Anna M; Faa Gavino; Höfler Heinz
Rapid identification of Wilson's disease carriers by denaturing high-performance liquid chromatography.
Preventive medicine 2002;35(3):278-84.
2002: Becker K; Höfler H
[Pathology of appendicitis]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2002;73(8):777-81.
2002: Becker Karl-Friedrich; Kremmer Elisabeth; Eulitz Manfred; Schulz Stephan; Mages Jörg; Handschuh Gabriele; Wheelock Margaret J; Cleton-Jansen Anne-Marie; Höfler Heinz; Becker Ingrid
Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies.
The Journal of pathology 2002;197(5):567-74.
2002: Nathrath Michaela H; Kuosaite Virginija; Rosemann Michael; Kremer Marcus; Poremba Christopher; Wakana Shigeharu; Yanagi Masayuki; Nathrath Walter B J; Höfler Heinz; Imai Kenji; Atkinson Michael J
Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.
Oncogene 2002;21(38):5975-80.
2002: Nathrath M; Kremer M; Letzel H; Remberger K; Höfler H; Ulle T
[Expression of genes of potential importance in the response to chemotherapy in osteosarcoma patients]
Klinische Pädiatrie 2002;214(4):230-5.
2002: Rüdiger Thomas; Höfler H; Kreipe H-H; Nizze H; Pfeifer U; Stein H; Dallenbach F E; Fischer H-P; Mengel M; von Wasielewski R; Müller-Hermelink H K
Quality assurance in immunohistochemistry: results of an interlaboratory trial involving 172 pathologists.
The American journal of surgical pathology 2002;26(7):873-82.
2002: Fritz Andreas; Walch Axel; Piotrowska Kamilla; Rosemann Michael; Schäffer Ekkehard; Weber Karin; Timper Andreas; Wildner Gerhild; Graw Jochen; Höfler Heinz; Atkinson Michael J
Recessive transmission of a multiple endocrine neoplasia syndrome in the rat.
Cancer research 2002;62(11):3048-51.
2002: Fuchs Margit; Hutzler Peter; Brunner Ingrid; Schlegel Jürgen; Mages Jörg; Reuning Ute; Hapke Sandra; Duyster Justus; Hirohashi Setsuo; Genda Takuya; Sakamoto Michiie; Uberall Florian; Höfler Heinz; Becker Karl-Friedrich; Luber Birgit
Motility enhancement by tumor-derived mutant E-cadherin is sensitive to treatment with epidermal growth factor receptor and phosphatidylinositol 3-kinase inhibitors.
Experimental cell research 2002;276(2):129-41.
2002: Werner M; Cabras A D; Höfler H
[Molecular pathologic diagnosis in solid tumors. What is clinically relevant?]
Der Pathologe 2002;23(3):170-3.
2002: Cabras Antonello Domenico; Weirich Gregor; Fend Falko; Nährig Jörg; Bordi Cesare; Höfler Heinz; Werner Martin
Oligoclonality of a "composite" gastric diffuse large B-cell lymphoma with areas of marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type.
Virchows Archiv : an international journal of pathology 2002;440(2):209-14.
2002: Bange Johannes; Prechtl Dieter; Cheburkin Yuri; Specht Katja; Harbeck Nadia; Schmitt Manfred; Knyazeva Tatjana; Müller Susanne; Gärtner Silvia; Sures Irmi; Wang Hongyang; Imyanitov Evgeny; Häring Hans-Ulrich; Knayzev Pjotr; Iacobelli Stefano; Höfler Heinz; Ullrich Axel
Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.
Cancer research 2002;62(3):840-7.
2002: Aubele Michaela; Auer Gert; Braselmann Herbert; Nährig Jörg; Zitzelsberger Horst; Quintanilla-Martinez Leticia; Smida Jan; Walch Axel; Höfler Heinz; Werner Martin
Chromosomal imbalances are associated with metastasis-free survival in breast cancer patients.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2002;24(2-3):77-87.
2002: Aubele Michaela; Werner Martin; Höfler Heinz
Genetic alterations in presumptive precursor lesions of breast carcinomas.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2002;24(2-3):69-76.
2001: Keller G; Hartmann A; Mueller J; Höfler H
Denaturing high pressure liquid chromatography (DHPLC) for the analysis of somatic p53 mutations.
Laboratory investigation; a journal of technical methods and pathology 2001;81(12):1735-7.
2001: Handschuh G; Luber B; Hutzler P; Höfler H; Becker K F
Single amino acid substitutions in conserved extracellular domains of E-cadherin differ in their functional consequences.
Journal of molecular biology 2001;314(3):445-54.
2001: Walch A; Bink K; Hutzler P; Böwering K; Letsiou I; Zitzelsberger H; Braselmann H; Stein H; Höfler H; Werner M
Sequential multilocus fluorescence in situ hybridization can detect complex patterns of increased gene dosage at the single cell level in tissue sections.
Laboratory investigation; a journal of technical methods and pathology 2001;81(10):1457-9.
2001: Harbeck N; Alt U; Berger U; Krüger A; Thomssen C; Jänicke F; Höfler H; Kates R E; Schmitt M
Prognostic impact of proteolytic factors (urokinase-type plasminogen activator, plasminogen activator inhibitor 1, and cathepsins B, D, and L) in primary breast cancer reflects effects of adjuvant systemic therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2757-64.
2001: Cabras A D; Candidus S; Fend F; Kremer M; Schulz S; Bordi C; Weirich G; Höfler H; Werner M
Biclonality of gastric lymphomas.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):961-7.
2001: Walch A; Specht K; Bink K; Zitzelsberger H; Braselmann H; Bauer M; Aubele M; Stein H; Siewert J R; Höfler H; Werner M
Her-2/neu gene amplification, elevated mRNA expression, and protein overexpression in the metaplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus.
Laboratory investigation; a journal of technical methods and pathology 2001;81(6):791-801.
2001: Bink K; Walch A; Feuchtinger A; Eisenmann H; Hutzler P; Höfler H; Werner M
TO-PRO-3 is an optimal fluorescent dye for nuclear counterstaining in dual-colour FISH on paraffin sections.
Histochemistry and cell biology 2001;115(4):293-9.
2001: Walch A; Specht K; Smida J; Aubele M; Zitzelsberger H; Höfler H; Werner M
Tissue microdissection techniques in quantitative genome and gene expression analyses.
Histochemistry and cell biology 2001;115(4):269-76.
2001: Chalmers I J; Aubele M; Hartmann E; Braungart E; Werner M; Höfler H; Atkinson M J
Mapping the chromosome 16 cadherin gene cluster to a minimal deleted region in ductal breast cancer.
Cancer genetics and cytogenetics 2001;126(1):39-44.
2001: Werner M; Becker K F; Keller G; Höfler H
Gastric adenocarcinoma: pathomorphology and molecular pathology.
Journal of cancer research and clinical oncology 2001;127(4):207-16.
2001: Kremer M; Sandherr M; Geist B; Cabras A D; Höfler H; Fend F
Epstein-Barr virus-negative Hodgkin's lymphoma after mycosis fungoides: molecular evidence for distinct clonal origin.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(2):91-7.
2001: Prechtel D; Harbeck N; Berger U; Höfler H; Werenskiold A K
Clinical relevance of T1-S, an oncogene-inducible, secreted glycoprotein of the immunoglobulin superfamily, in node-negative breast cancer.
Laboratory investigation; a journal of technical methods and pathology 2001;81(2):159-65.
2001: Specht K; Richter T; Müller U; Walch A; Werner M; Höfler H
Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue.
The American journal of pathology 2001;158(2):419-29.
2001: Zitzelsberger H; Engert D; Walch A; Kulka U; Aubele M; Höfler H; Bauchinger M; Werner M
Chromosomal changes during development and progression of prostate adenocarcinomas.
British journal of cancer 2001;84(2):202-8.
2001: Höfler H
[Organization and contents of future research in pathology]
Verhandlungen der Deutschen Gesellschaft für Pathologie 2001;85():37-43.
2001: Walch A; Bink K; Hutzler P; Zitzelsberger H; Braselmann H; Aubele M; Höfler H; Werner M
[Oncogene amplification and genetic heterogeneity in the metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus]
Verhandlungen der Deutschen Gesellschaft für Pathologie 2001;85():257-63.
2001: Braungart E; Hartman E; Bechler K; Höfler H; Atkinson M J
The intracellular domain of cadherin-11 is not required for the induction of cell aggregation, adhesion or gap-junction formation.
Cell communication & adhesion 2001;8(1):15-27.
2000: Mueller J; Brebeck B; Schmalfeldt B; Kuhn W; Graeff H; Höfler H
Stromelysin-3 expression in invasive ovarian carcinomas and tumours of low malignant potential.
Virchows Archiv : an international journal of pathology 2000;437(6):618-24.
2000: Yanagi M; Keller G; Mueller J; Walch A; Werner M; Stein H J; Siewert J R; Höfler H
Comparison of loss of heterozygosity and microsatellite instability in adenocarcinomas of the distal esophagus and proximal stomach.
Virchows Archiv : an international journal of pathology 2000;437(6):605-10.
2000: Grundei T; Vogelsang H; Ott K; Mueller J; Scholz M; Becker K; Fink U; Siewert J R; Höfler H; Keller G
Loss of heterozygosity and microsatellite instability as predictive markers for neoadjuvant treatment in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4782-8.
2000: Walch A; Bink K; Hutzler P; Höfler H; Werner M
HER-2/neu gene amplification by FISH predicts poor survival in Barrett's esophagus-associated adenocarcinoma.
Human pathology 2000;31(10):1332-4.
2000: Cabras A D; Kremer M; Schulz S; Werner M; Hummel M; Komminoth P; Höfler G; Höfler H
Quality assessment in diagnostic molecular pathology: experience from a German-Austrian-Swiss multicenter trial.
Virchows Archiv : an international journal of pathology 2000;437(1):46-51.
2000: Walch A K; Zitzelsberger H F; Bink K; Hutzler P; Bruch J; Braselmann H; Aubele M M; Mueller J; Stein H; Siewert J R; Höfler H; Werner M
Molecular genetic changes in metastatic primary Barrett's adenocarcinoma and related lymph node metastases: comparison with nonmetastatic Barrett's adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2000;13(7):814-24.
2000: Schulz S; Becker K F; Braungart E; Reichmuth C; Klamt B; Becker I; Atkinson M; Gessler M; Höfler H
Molecular analysis of E-cadherin and cadherin-11 in Wilms' tumours.
The Journal of pathology 2000;191(2):162-9.
2000: Nährig J; Richter T; Kowolik J; Kuhn W; Avril N; Höfler H; Werner M
Comparison of different histopathological methods for the examination of sentinel lymph nodes in breast cancer.
Anticancer research 2000;20(3B):2209-12.
2000: Luber B; Candidus S; Handschuh G; Mentele E; Hutzler P; Feller S; Voss J; Höfler H; Becker K F
Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate.
Cell adhesion and communication 2000;7(5):391-408.
2000: Cummings M C; Aubele M; Mattis A; Purdie D; Hutzler P; Höfler H; Werner M
Increasing chromosome 1 copy number parallels histological progression in breast carcinogenesis.
British journal of cancer 2000;82(6):1204-10.
2000: Werenskiold A K; Prechtel D; Harbeck N; Höfler H
Tumor-associated overexpression of the soluble T1-S receptor in lymph node-negative breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2000;9(1):26-34.
2000: Aubele M M; Cummings M C; Mattis A E; Zitzelsberger H F; Walch A K; Kremer M; Höfler H; Werner M
Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2000;9(1):14-9.
2000: Walch A K; Zitzelsberger H F; Bruch J; Keller G; Angermeier D; Aubele M M; Mueller J; Stein H; Braselmann H; Siewert J R; Höfler H; Werner M
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence.
The American journal of pathology 2000;156(2):555-66.
2000: Walch A; Komminoth P; Hutzler P; Aubele M; Höfler H; Werner M
Microdissection of tissue sections: application to the molecular genetic characterisation of premalignant lesions.
Pathobiology : journal of immunopathology, molecular and cellular biology 2000;68(1):9-17.
2000: Aubele M; Mattis A; Zitzelsberger H; Walch A; Kremer M; Welzl G; Höfler H; Werner M
Extensive ductal carcinoma In situ with small foci of invasive ductal carcinoma: evidence of genetic resemblance by CGH.
International journal of cancer. Journal international du cancer 2000;85(1):82-6.
2000: Schuhmacher C; Becker K; Dittler H J; Höfler H; Siewert J R; Stein H J
Fibrovascular esophageal polyp as a diagnostic challenge.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2000;13(4):324-7.
2000: Walch A; Bink K; Gais P; Stangl S; Hutzler P; Aubele M; Mueller J; Höfler H; Werner M
Evaluation of c-erbB-2 overexpression and Her-2/neu gene copy number heterogeneity in Barrett's adenocarcinoma.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 2000;20(1):25-32.
1999: Becker K F; Kremmer E; Eulitz M; Becker I; Handschuh G; Schuhmacher C; Müller W; Gabbert H E; Ochiai A; Hirohashi S; Höfler H
Analysis of E-cadherin in diffuse-type gastric cancer using a mutation-specific monoclonal antibody.
The American journal of pathology 1999;155(6):1803-9.
1999: Werner M; Mattis A; Aubele M; Cummings M; Zitzelsberger H; Hutzler P; Höfler H
20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast.
Virchows Archiv : an international journal of pathology 1999;435(5):469-72.
1999: D'Adda T; Candidus S; Denk H; Bordi C; Höfler H
Gastric neuroendocrine neoplasms: tumour clonality and malignancy-associated large X-chromosomal deletions.
The Journal of pathology 1999;189(3):394-401.
1999: Keller G; Vogelsang H; Becker I; Hutter J; Ott K; Candidus S; Grundei T; Becker K F; Mueller J; Siewert J R; Höfler H
Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation.
The American journal of pathology 1999;155(2):337-42.
1999: Handschuh G; Candidus S; Luber B; Reich U; Schott C; Oswald S; Becke H; Hutzler P; Birchmeier W; Höfler H; Becker K F
Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility.
Oncogene 1999;18(30):4301-12.
1999: Schuhmacher C; Becker K F; Reich U; Schenk U; Mueller J; Siewert J R; Höfler H
Rapid detection of mutated E-cadherin in peritoneal lavage specimens from patients with diffuse-type gastric carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1999;8(2):66-70.
1999: Schuhmacher C; Becker I; Oswald S; Atkinson M J; Nekarda H; Becker K F; Mueller J; Siewert J R; Höfler H
Loss of immunohistochemical E-cadherin expression in colon cancer is not due to structural gene alterations.
Virchows Archiv : an international journal of pathology 1999;434(6):489-95.
1999: Harbeck N; Dettmar P; Thomssen C; Berger U; Ulm K; Kates R; Höfler H; Jänicke F; Graeff H; Schmitt M
Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers: 6-year median follow-up.
British journal of cancer 1999;80(3-4):419-26.
1999: Werenskiold A K; Schmidt J; Rupp B; Gössner W; Höfler H
Suppression of T1-receptor expression by antisense RNA abrogates differentiation of osteogenic osteosarcoma cells.
Laboratory investigation; a journal of technical methods and pathology 1999;79(5):529-36.
1999: Braungart E; Schumacher C; Hartmann E; Nekarda H; Becker K F; Höfler H; Atkinson M J
Functional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancer.
The Journal of pathology 1999;187(5):530-4.
1999: Aubele M; Mattis A; Zitzelsberger H; Walch A; Kremer M; Hutzler P; Höfler H; Werner M
Intratumoral heterogeneity in breast carcinoma revealed by laser-microdissection and comparative genomic hybridization.
Cancer genetics and cytogenetics 1999;110(2):94-102.
1999: Werner M; Mueller J; Walch A; Höfler H
The molecular pathology of Barrett's esophagus.
Histology and histopathology 1999;14(2):553-9.
1999: Kuhn W; Schmalfeldt B; Reuning U; Pache L; Berger U; Ulm K; Harbeck N; Späthe K; Dettmar P; Höfler H; Jänicke F; Schmitt M; Graeff H
Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc.
British journal of cancer 1999;79(11-12):1746-51.
1999: Becker K; Fumagalli U; Mueller J D; Fink U; Siewert J R; Höfler H
Neoadjuvant chemotherapy for patients with locally advanced gastric carcinoma: effect on tumor cell microinvolvement of regional lymph nodes.
Cancer 1999;85(7):1484-9.
1999: Harbeck N; Thomssen C; Berger U; Ulm K; Kates R E; Höfler H; Jänicke F; Graeff H; Schmitt M
Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse.
Breast cancer research and treatment 1999;54(2):147-57.
1999: Markus M A; Reichmuth C; Atkinson M J; Reich U; Hoffmann I; Balling R; Anderer U; Höfler H
Cadherin-11 is highly expressed in rhabdomyosarcomas and during differentiation of myoblasts in vitro.
The Journal of pathology 1999;187(2):164-72.
1999: Becker I; Becker K F; Kremmer E; Eulitz M; Handschuh G; Höfler H
[Novel mutation-specific monoclonal E-cadherin antibodies make possible allele differentiation at the protein level in tumors]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():233-9.
1999: Höfler H
[Diffuse stomach carcinoma: from H&E diagnosis and molecular pathology to specific therapy]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():148-54.
1999: Mueller J; Mueller E; Keller G; Bethke B; Stolte M; Höfler H
[Are there differences between ex adenoma and de novo colorectal carcinomas?]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():139-47.
1999: Jütting U; Gais P; Rodenacker K; Böhm J; Koch S; Präuer H W; Höfler H
Diagnosis and prognosis of neuroendocrine tumours of the lung by means of high resolution image analysis.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1999;18(2):109-19.
1999: Becker K F; Reich U; Schott C; Becker I; Berx G; van Roy F; Höfler H
Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online.
Human mutation 1999;13(2):171.
1998: Aubele M; Zitzelsberger H; Schenck U; Walch A; Höfler H; Werner M
Distinct cytogenetic alterations in squamous intraepithelial lesions of the cervix revealed by laser-assisted microdissection and comparative genomic hybridization.
Cancer 1998;84(6):375-9.
1998: Mueller J D; Haegle N; Keller G; Mueller E; Saretzky G; Bethke B; Stolte M; Höfler H
Loss of heterozygosity and microsatellite instability in de novo versus ex-adenoma carcinomas of the colorectum.
The American journal of pathology 1998;153(6):1977-84.
1998: Mueller J D; Heider K H; Oberhuber G; Mueller E; Bethke B; Stolte M; Höfler H
Comparison of CD44 expression in early colorectal carcinomas of the de novo and ex adenoma types.
Virchows Archiv : an international journal of pathology 1998;433(5):407-14.
1998: Zitzelsberger H; Kulka U; Lehmann L; Walch A; Smida J; Aubele M; Lörch T; Höfler H; Bauchinger M; Werner M
Genetic heterogeneity in a prostatic carcinoma and associated prostatic intraepithelial neoplasia as demonstrated by combined use of laser-microdissection, degenerate oligonucleotide primed PCR and comparative genomic hybridization.
Virchows Archiv : an international journal of pathology 1998;433(4):297-304.
1998: Walch A K; Zitzelsberger H F; Aubele M M; Mattis A E; Bauchinger M; Candidus S; Präuer H W; Werner M; Höfler H
Typical and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization.
The American journal of pathology 1998;153(4):1089-98.
1998: Weirich G; Sandherr M; Fellbaum C; Richter T; Schmidt L; Kinjerski T; Dietzfelbinger H; Rastetter J; Höfler H
Molecular evidence of bone marrow involvement in advanced case ot Tgammadelta lymphoma with secondary myelofibrosis.
Human pathology 1998;29(7):761-5.
1998: Harbeck N; Dettmar P; Thomssen C; Henselmann B; Kuhn W; Ulm K; Jänicke F; Höfler H; Graeff H; Schmitt M
Prognostic impact of tumor biological factors on survival in node-negative breast cancer.
Anticancer research 1998;18(3C):2187-97.
1998: Thomssen C; Oppelt P; Jänicke F; Ulm K; Harbeck N; Höfler H; Kuhn W; Graeff H; Schmitt M
Identification of low-risk node-negative breast cancer patients by tumor biological factors PAI-1 and cathepsin L.
Anticancer research 1998;18(3C):2173-80.
1998: Keller G; Rudelius M; Vogelsang H; Grimm V; Wilhelm M G; Mueller J; Siewert J R; Höfler H
Microsatellite instability and loss of heterozygosity in gastric carcinoma in comparison to family history.
The American journal of pathology 1998;152(5):1281-9.
1998: Prechtel D; Werenskiold A K; Prechtel K; Keller G; Höfler H
Frequent loss of heterozygosity at chromosome 13q12-13 with BRCA2 markers in sporadic male breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1998;7(1):57-62.
1998: Hillemanns M; Päsold S; Böttcher K; Höfler H
[Prognostic factors of gastrointestinal stromal tumors of the stomach]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1998;82():261-6.
1997: Siewert J R; Fink U; Sendler A; Becker K; Böttcher K; Feldmann H J; Höfler H; Mueller J; Molls M; Nekarda H; Roder J D; Stein H J
Gastric Cancer.
Current problems in surgery 1997;34(11):835-939.
1997: Roehrl M H; Becker K F; Becker I; Höfler H
Efficiency of single-cell polymerase chain reaction from stained histologic slides and integrity of DNA in archival tissue.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1997;6(5):292-7.
1997: Becker I; Becker K F; Röhrl M H; Höfler H
Laser-assisted preparation of single cells from stained histological slides for gene analysis.
Histochemistry and cell biology 1997;108(4-5):447-51.
1997: Mueller J D; Pütz B; Höfler H
Self-sustained sequence replication (3SR): an alternative to PCR.
Histochemistry and cell biology 1997;108(4-5):431-7.
1997: Bumm R; Feussner H; Bartels H; Stein H; Dittler H J; Höfler H; Siewert J R
Radical transhiatal esophagectomy with two-field lymphadenectomy and endodissection for distal esophageal adenocarcinoma.
World journal of surgery 1997;21(8):822-31.
1997: Weirich G; Schneider P; Fellbaum C; Brauch H; Nathrath W; Scholz M; Präuer H; Höfler H
p53 alterations in thymic epithelial tumours.
Virchows Archiv : an international journal of pathology 1997;431(1):17-23.
1997: Schmitt M; Harbeck N; Thomssen C; Wilhelm O; Magdolen V; Reuning U; Ulm K; Höfler H; Jänicke F; Graeff H
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy.
Thrombosis and haemostasis 1997;78(1):285-96.
1997: Kestlmeier R; Busch R; Fellbaum C; Boettcher K; Reich U; Siewert J R; Höfler H
[Incidence and prognostic significance of epithelioid cell reactions and microcarcinoses in regional lymph nodes in stomach carcinoma]
Der Pathologe 1997;18(2):124-30.
1997: Mueller J; Mueller E; Arras E; Bethke B; Stolte M; Höfler H
Stromelysin-3 expression in early (pT1) carcinomas and pseudoinvasive lesions of the colorectum.
Virchows Archiv : an international journal of pathology 1997;430(3):213-9.
1997: D'Alessandro I; Zitzelsberger H; Hutzler P; Lehmann L; Braselmann H; Chimenti S; Höfler H
Numerical aberrations of chromosome 7 detected in 15 microns paraffin-embedded tissue sections of primary cutaneous melanomas by fluorescence in situ hybridization and confocal laser scanning microscopy.
Journal of cutaneous pathology 1997;24(2):70-5.
1997: Höfler H; Stier A; Schusdziarra V; Siewert J R
[Classification of neuroendocrine tumors of the gastrointestinal tract and pancreas and its therapeutic relevance]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1997;68(2):107-15.
1997: Böhm J; Fellbaum C; Bautz W; Präuer H W; Höfler H
Pulmonary nodule caused by an alveolar adenoma of the lung.
Virchows Archiv : an international journal of pathology 1997;430(2):181-4.
1997: Aubele M; Zitzelsberger H; Szücs S; Werner M; Braselmann H; Hutzler P; Rodenacker K; Lehmann L; Minkus G; Höfler H
Comparative FISH analysis of numerical chromosome 7 abnormalities in 5-micron and 15-micron paraffin-embedded tissue sections from prostatic carcinoma.
Histochemistry and cell biology 1997;107(2):121-6.
1997: Höfler H
[Neuroendocrine tumors of the lung]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1997;81():118-24.
1997: Schmitt M; Thomssen C; Ulm K; Seiderer A; Harbeck N; Höfler H; Jänicke F; Graeff H
Time-varying prognostic impact of tumour biological factors urokinase (uPA), PAI-1 and steroid hormone receptor status in primary breast cancer.
British journal of cancer 1997;76(3):306-11.
1997: Dettmar P; Harbeck N; Thomssen C; Pache L; Ziffer P; Fizi K; Jänicke F; Nathrath W; Schmitt M; Graeff H; Höfler H
Prognostic impact of proliferation-associated factors MIB1 (Ki-67) and S-phase in node-negative breast cancer.
British journal of cancer 1997;75(10):1525-33.
1996: Becker I; Becker K F; Röhrl M H; Minkus G; Schütze K; Höfler H
Single-cell mutation analysis of tumors from stained histologic slides.
Laboratory investigation; a journal of technical methods and pathology 1996;75(6):801-7.
1996: Reichmuth C; Markus M A; Hillemanns M; Atkinson M J; Unni K K; Saretzki G; Höfler H
The diagnostic potential of the chromosome translocation t(2;13) in rhabdomyosarcoma: a Pcr study of fresh-frozen and paraffin-embedded tumour samples.
The Journal of pathology 1996;180(1):50-7.
1996: Glavac D; Neumann H P; Wittke C; Jaenig H; Masek O; Streicher T; Pausch F; Engelhardt D; Plate K H; Höfler H; Chen F; Zbar B; Brauch H
Mutations in the VHL tumor suppressor gene and associated lesions in families with von Hippel-Lindau disease from central Europe.
Human genetics 1996;98(3):271-80.
1996: Aubele M; Auer G; Höfler H
Analysis of DNA and morphometry in breast carcinoma.
Histochemistry and cell biology 1996;106(2):241-5.
1996: Zitzelsberger H; Szücs S; Robens E; Weier H U; Höfler H; Bauchinger M
Combined cytogenetic and molecular genetic analyses of fifty-nine untreated human prostate carcinomas.
Cancer genetics and cytogenetics 1996;90(1):37-44.
1996: Becker K F; Reich U; Handschuh G; Dalke C; Höfler H
Non-radioactive protein truncation test (nrPTT) for rapid detection of gene mutations.
Trends in genetics : TIG 1996;12(7):250.
1996: Wagner S N; Atkinson M J; Thanner S; Schmitt M; Wilhelm O; Rotter M; Höfler H
Type-1 plasminogen activator inhibitor in human renal cell carcinoma.
The Journal of pathology 1996;179(1):95-9.
1996: Böhm J; Koch S; Gais P; Jütting U; Präuer H W; Höfler H
Prognostic value of MIB-1 in neuroendocrine tumours of the lung.
The Journal of pathology 1996;178(4):402-9.
1996: Niedermeyer H P; Peris K; Höfler H
Pilomatrix carcinoma with multiple visceral metastases. Report of a case.
Cancer 1996;77(7):1311-4.
1996: Wagner S N; Atkinson M J; Wagner C; Höfler H; Schmitt M; Wilhelm O
Sites of urokinase-type plasminogen activator expression and distribution of its receptor in the normal human kidney.
Histochemistry and cell biology 1996;105(1):53-60.
1996: Candidus S; Bischoff P; Becker K F; Höfler H
No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas.
Cancer research 1996;56(1):49-52.
1995: Becker K F; Reich U; Schott C; Höfler H
Single nucleotide polymorphisms in the human E-cadherin gene.
Human genetics 1995;96(6):739-40.
1995: Hölscher A H; Bollschweiler E; Bumm R; Bartels H; Höfler H; Siewert J R
Prognostic factors of resected adenocarcinoma of the esophagus.
Surgery 1995;118(5):845-55.
1995: Peris K; Keller G; Chimenti S; Amantea A; Kerl H; Höfler H
Microsatellite instability and loss of heterozygosity in melanoma.
The Journal of investigative dermatology 1995;105(4):625-8.
1995: Höfler H; Pütz B; Mueller J D; Neubert W; Sutter G; Gais P
In situ amplification of measles virus RNA by the self-sustained sequence replication reaction.
Laboratory investigation; a journal of technical methods and pathology 1995;73(4):577-85.
1995: Keller G; Rotter M; Vogelsang H; Bischoff P; Becker K F; Mueller J; Brauch H; Siewert J R; Höfler H
Microsatellite instability in adenocarcinomas of the upper gastrointestinal tract. Relation to clinicopathological data and family history.
The American journal of pathology 1995;147(3):593-600.
1995: Schmalfeldt B; Kuhn W; Reuning U; Pache L; Dettmar P; Schmitt M; Jänicke F; Höfler H; Graeff H
Primary tumor and metastasis in ovarian cancer differ in their content of urokinase-type plasminogen activator, its receptor, and inhibitors types 1 and 2.
Cancer research 1995;55(18):3958-63.
1995: Wagner S N; Wagner C; Höfler H; Atkinson M J; Goos M
Expression cloning of the cDNA encoding a melanoma-associated Ag recognized by mAb HMB-45. Identification as melanocyte-specific Pmel 17 cDNA.
Laboratory investigation; a journal of technical methods and pathology 1995;73(2):229-35.
1995: Sendler A; Dittler H J; Feussner H; Nekarda H; Bollschweiler E; Fink U; Helmberger H; Höfler H; Siewert J R
Preoperative staging of gastric cancer as precondition for multimodal treatment.
World journal of surgery 1995;19(4):501-8.
1995: Wagner S N; Atkinson M J; Thanner S; Wagner C; Schmitt M; Wilhelm O; Rotter M; Höfler H
Modulation of urokinase and urokinase receptor gene expression in human renal cell carcinoma.
The American journal of pathology 1995;147(1):183-92.
1995: Brauch H; Kishida T; Glavac D; Chen F; Pausch F; Höfler H; Latif F; Lerman M I; Zbar B; Neumann H P
Von Hippel-Lindau (VHL) disease with pheochromocytoma in the Black Forest region of Germany: evidence for a founder effect.
Human genetics 1995;95(5):551-6.
1995: Wagner S N; Ockenfels H M; Wagner C; Höfler H; Goos M
Ras gene mutations: a rare event in nonmetastatic primary malignant melanoma.
The Journal of investigative dermatology 1995;104(5):868-71.
1995: Weirich G; Funk A; Hoepner I; Heider U; Noll S; Pütz B; Fellbaum C; Höfler H
PCR-based assays for the detection of monoclonality in non-Hodgkin's lymphoma: application to formalin-fixed, paraffin-embedded tissue and decalcified bone marrow samples.
Journal of molecular medicine (Berlin, Germany) 1995;73(5):235-41.
1995: Siewert J R; Sendler A; Dittler H J; Fink U; Höfler H
Staging gastrointestinal cancer as a precondition for multimodal treatment.
World journal of surgery 1995;19(2):168-77.
1994: Szücs S; Zitzelsberger H; Breul J; Bauchinger M; Höfler H
Two-phase short-term culture method for cytogenetic investigations from human prostate carcinoma.
The Prostate 1994;25(5):225-35.
1994: Becker K F; Atkinson M J; Reich U; Becker I; Nekarda H; Siewert J R; Höfler H
E-cadherin gene mutations provide clues to diffuse type gastric carcinomas.
Cancer research 1994;54(14):3845-52.
1994: Zitzelsberger H; Szücs S; Weier H U; Lehmann L; Braselmann H; Enders S; Schilling A; Breul J; Höfler H; Bauchinger M
Numerical abnormalities of chromosome 7 in human prostate cancer detected by fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with centromere-specific DNA probes.
The Journal of pathology 1994;172(4):325-35.
1994: Höfler H
[Prognostic factors in pancreatic cancer]
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1994;65(4):253-7.
1994: Heinzmann U; Höfler H
Detection of epidermal growth factor receptor by scanning electron microscopy.
Histochemistry 1994;101(2):127-34.
1994: Funk A; Rudel J; Fellbaum C; Höfler H
[Specific in situ labeling of apoptosis shows different rates of programmed cell death in non-Hodgkin lymphomas]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():318-20.
1994: Peris K; Niedermeyer H; Cerroni L; Radaskiewicz T; Chimenti S; Höfler H
Detection of Epstein-Barr virus genome in primary cutaneous T and B cell lymphomas and pseudolymphomas.
Archives of dermatological research 1994;286(7):364-8.
1994: Kunth K; Höfler H; Atkinson M J
[Quantification of messenger RNA expression in tumors: which standard should be used for best RNA normalization?]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():226-30.
1994: Höfler H; Mueller J
In situ hybridization in pathology.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():124-35.
1993: Lohmann D R; Fesseler B; Pütz B; Reich U; Böhm J; Präuer H; Wünsch P H; Höfler H
Infrequent mutations of the p53 gene in pulmonary carcinoid tumors.
Cancer research 1993;53(23):5797-801.
1993: Becker K F; Atkinson M J; Reich U; Huang H H; Nekarda H; Siewert J R; Höfler H
Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas.
Human molecular genetics 1993;2(6):803-4.
1993: Lohmann D; Pütz B; Reich U; Böhm J; Präuer H; Höfler H
Mutational spectrum of the p53 gene in human small-cell lung cancer and relationship to clinicopathological data.
The American journal of pathology 1993;142(3):907-15.
1993: Lohmann D; Ruhri C; Schmitt M; Graeff H; Höfler H
Accumulation of p53 protein as an indicator for p53 gene mutation in breast cancer. Occurrence of false-positives and false-negatives.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1993;2(1):36-41.
1993: Böhm J; Kacic V; Gais P; Präuer H W; Höfler H
Prognostic value of nucleolar organizer regions in neuroendocrine tumours of the lung.
Histochemistry 1993;99(1):85-90.
1993: Jänicke F; Schmitt M; Pache L; Ulm K; Harbeck N; Höfler H; Graeff H
Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer.
Breast cancer research and treatment 1993;24(3):195-208.
1993: Lohmann D R; Funk A; Niedermeyer H P; Häupel S; Höfler H
Identification of p53 gene mutations in gastrointestinal and pancreatic carcinoids by nonradioisotopic SSCA.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;64(5):293-6.
1993: Harbeck N; Schüren E; Yamamoto N; Pache L; Schmitt M; Jänicke F; Dettmar P; Höfler H; Graeff H
[DNA flow cytometric analysis in primary breast cancer. S-phase and ploidy status as prognostic factors and their correlation to tumor-associated proteolytic factors]
Gynäkologisch-geburtshilfliche Rundschau 1993;33 Suppl 1():303-4.
1993: Harbeck N; Schüren E; Yamamoto N; Schmitt M; Höfler H; Graeff H
[Development of a technique for isolation of intact tumor cells from fresh breast or ovarian cancer tissue. Use in analysis of tumor-associated proteolytic factors]
Gynäkologisch-geburtshilfliche Rundschau 1993;33 Suppl 1():277-9.
1993: Wagner S N; Müller R; Boehm J; Pütz B; Wünsch P H; Höfler H
Neuroendocrine neoplasms of the lung are not associated with point mutations at codon 12 of the Ki-ras gene.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;63(5):325-9.
1993: Szücs S; Zitzelsberger H; Roter M; Bauchinger M; Höfler H
[Cytogenetic investigations in primary prostate carcinomas]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1993;77():138-41.
1992: Rotter M; Block T; Busch R; Thanner S; Höfler H
Expression of HER-2/neu in renal-cell carcinoma. Correlation with histologic subtypes and differentiation.
International journal of cancer. Journal international du cancer 1992;52(2):213-7.
1992: Wagner S N; Ruhri C; Kunth K; Holecek B U; Goos M; Höfler H; Atkinson M J
Expression of stromelysin 3 in the stromal elements of human basal cell carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1992;1(3):200-5.
1992: Lohmann D; Horsthemke B; Gillessen-Kaesbach G; Stefani F H; Höfler H
Detection of small RB1 gene deletions in retinoblastoma by multiplex PCR and high-resolution gel electrophoresis.
Human genetics 1992;89(1):49-53.
1992: Strauss P G; Mitreiter K; Zitzelsberger H; Luz A; Schmidt J; Erfle V; Höfler H
Elevated p53 RNA expression correlates with incomplete osteogenic differentiation of radiation-induced murine osteosarcomas.
International journal of cancer. Journal international du cancer 1992;50(2):252-8.
1992: Wirnsberger G H; Becker H; Ziervogel K; Höfler H
Diagnostic immunohistochemistry of neuroblastic tumors.
The American journal of surgical pathology 1992;16(1):49-57.
1992: Heinzmann U; Höfler H
EGF-receptor immunolabeling as shown by LM and SEM.
Progress in histochemistry and cytochemistry 1992;26(1-4):88-94.
1992: Fellbaum C; Radaszkiewicz T; Ruhri C; Pütz B; Lehmacher W; Höfler H
c-myc mRNA expression in non-Hodgkin's lymphomas.
Virchows Archiv. B, Cell pathology including molecular pathology 1992;62(1):61-8.
1992: Rohde D; Niedermeyer H; Fellbaum C; Hansmann M L; Busch R; Lauder I; Höfler H; Fischer R
[Nodular paragranuloma and Epstein-Barr virus: frequency of EBV DNA and clinical relevance]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1992;76():177-80.
1992: Niedermeyer H; Fellbaum C; Hansmann M L; Kraus I; Alavaikko M J; Busch R; Pütz B; Fischer R; Höfler H
[Influence of Epstein-Barr virus genome on patient survival in Hodgkin's disease]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1992;76():173-6.
1991: Böhm J; Röder-Weber M; Höfler H; Kolben M
Bilateral stromal Leydig cell tumour of the ovary. Case report and literature review.
Pathology, research and practice 1991;187(2-3):348-52; discussion 352-3.
1991: Peris K; Cerroni L; Chimenti S; Soyer H P; Kerl H; Höfler H
Proto-oncogene expression in dermal naevi and melanomas.
Archives of dermatological research 1991;283(8):500-5.
1990: Kolben M; Jänicke F; Böhm J; Röder-Weber M; Graeff H; Höfler H
[Androgenization in postmenopause in rare ovarian tumors--2 case reports]
Geburtshilfe und Frauenheilkunde 1990;50(8):650-2.
1990: Pfragner R; Höfler H; Behmel A; Ingolic E; Walser V
Establishment and characterization of continuous cell line MTC-SK derived from a human medullary thyroid carcinoma.
Cancer research 1990;50(13):4160-6.
1990: Pagani A; Papotti M; Höfler H; Weiler R; Winkler H; Bussolati G
Chromogranin A and B gene expression in carcinomas of the breast. Correlation of immunocytochemical, immunoblot, and hybridization analyses.
The American journal of pathology 1990;136(2):319-27.
1990: Becker H; Wirnsberger G; Ziervogel K; Höfler H
Immunohistochemical markers in (ganglio)neuroblastomas.
Acta histochemica. Supplementband 1990;38():107-14.
1990: Klimpfinger M; Zisser G; Ruhri C; Pütz B; Steindorfer P; Höfler H
Expression of c-myc and c-fos mRNA in colorectal carcinoma in man.
Virchows Archiv. B, Cell pathology including molecular pathology 1990;59(3):165-71.
1990: Höfler H
[Oncogenes and oncogene products--possibilities and significance of their detection]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():319-27.
1989: Höfler H; Wolfe H J
mRNA detection by in situ hybridization with radioactive probes.
Acta histochemica. Supplementband 1989;37():79-82.
1988: Höfler H; Wirnsberger G; Pütz B; Ruhri C
Histochemical demonstration of lectin binding sites in neuroendocrine tumors.
Acta histochemica. Supplementband 1988;36():273-6.
1988: Höfler H; Ruhri C; Pütz B; Wirnsberger G; Hauser H
Oncogene expression in endocrine pancreatic tumors.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;55(6):355-61.
1988: Klimpfinger M; Ruhri C; Pütz B; Pfragner R; Wirnsberger G; Höfler H
Oncogene expression in a medullary thyroid carcinoma.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;54(4):256-9.
1987: Höfler H; Ruhri C; Pütz B; Wirnsberger G
[Oncogene expression in endocrine pancreatic tumors]
Verhandlungen der Deutschen Gesellschaft für Pathologie 1987;71():306-10.
1987: Höfler H; Pütz B; Ruhri C; Wirnsberger G; Klimpfinger M; Smolle J
Simultaneous localization of calcitonin mRNA and peptide in a medullary thyroid carcinoma.
Virchows Archiv. B, Cell pathology including molecular pathology 1987;54(3):144-51.

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