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Frans Hogervorst

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Setareh Moghadasi; N Hofland; Frans B L Hogervorst; Maaike P G Vreeswijk; Juul Wijnen; Joyce N Wouts; Christi J van Asperen
Variants of uncertain significance in BRCA1 and BRCA2 assessment of in silico analysis and a proposal for communication in genetic counselling.
Yael Laitman; Lesley McGuffog; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Kenneth Offit; Susan Peock; Paolo Peterlongo; Paolo Radice; Johanna Rantala; Rita K Schmutzler; Olga M Sinilnikova; Barbara Wappenschmidt; Ido Wolf; Antonis C Antoniou; Adalgeir Arason; Maria Adelaide Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Fergus Couch; Douglas F Easton; Patricia Ganz; Andrew K Godwin; Sue Healey; Frans B L Hogervorst; Claudine Isaacs; Tomas Kirchhoff; Karoline B Kuchenbaecker; Eitan Friedman
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Simon A Joosse; Kim I M Brandwijk; Peter Devilee; Frans B L Hogervorst; Senno Verhoef; Jelle Wesseling; petra nederlof
Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH.

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2013: Setareh Moghadasi; N Hofland; Frans B L Hogervorst; Maaike P G Vreeswijk; Juul Wijnen; Joyce N Wouts; Christi J van Asperen
Variants of uncertain significance in BRCA1 and BRCA2 assessment of in silico analysis and a proposal for communication in genetic counselling.
Journal of medical genetics 2013;50(2):74-9.
2012: Yael Laitman; Lesley McGuffog; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Kenneth Offit; Susan Peock; Paolo Peterlongo; Paolo Radice; Johanna Rantala; Rita K Schmutzler; Olga M Sinilnikova; Barbara Wappenschmidt; Ido Wolf; Antonis C Antoniou; Adalgeir Arason; Maria Adelaide Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Fergus Couch; Douglas F Easton; Patricia Ganz; Andrew K Godwin; Sue Healey; Frans B L Hogervorst; Claudine Isaacs; Tomas Kirchhoff; Karoline B Kuchenbaecker; Eitan Friedman
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2012;132(3):1119-26.
2012: Simon A Joosse; Kim I M Brandwijk; Peter Devilee; Frans B L Hogervorst; Senno Verhoef; Jelle Wesseling; petra nederlof
Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH.
Breast cancer research and treatment 2012;132(2):379-89.
2012: Amanda B Spurdle; Dominique Stoppa-Lyonnet; Sean V Tavtigian; Barbara Wappenschmidt; Fergus J. Couch; Andrew Devereau; David E Goldgar; Sue Healey; Frans B L Hogervorst; Alvaro N A Monteiro; Katherine L Nathanson; Paolo Radice
ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes.
Human mutation 2012;33(1):2-7.
2011: Muriel A Adank; Johan J P Gille; Frans B L Hogervorst; Marianne A Jonker; Irma Kluijt; Hanne Meijers-Heijboer; Wolter J Mooi; Rogier A Oldenburg; Marjanka K Schmidt; Ans M W van den Ouweland; Aad W van der Vaart; Saskia E van Mil; Quinten Waisfisz
CHEK2*1100delC homozygosity is associated with a high breast cancer risk in women.
Journal of medical genetics 2011;48(12):860-3.
2011: M A Didraga; Frans B L Hogervorst; Nicoline Hoogerbrugge; S A Joosse; M J L Ligtenberg; Rogier A Oldenburg; E H van Beers; Senno Verhoef; Lodewyk F A Wessels; K I M Brandwijk; Peter Devilee; petra nederlof
A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of genetically related patients.
Breast cancer research and treatment 2011;130(2):425-36.
2011: Marijke R Wevers; Margreet G E M Ausems; Senno Verhoef; Eveline M A Bleiker; Daniela E E Hahn; Frans B L Hogervorst; Rob B van der Luijt; Heiddis B Valdimarsdottir; Richard van Hillegersberg; Emiel J T H Rutgers; Neil K Aaronson
Behavioral and psychosocial effects of rapid genetic counseling and testing in newly diagnosed breast cancer patients: design of a multicenter randomized clinical trial.
BMC cancer 2011;11():6.
2010: Nic Waddell; Jeremy Arnold; Sibylle Cocciardi; Leonard da Silva; Anna Marsh; Joan Riley; Cameron N Johnstone; Mohammed Orloff; Guillaume Assie; Charis Eng; Lynne Reid; Patricia Keith; Max Yan; Stephen Fox; Peter Devilee; Andrew K Godwin; Frans B L Hogervorst; Fergus J. Couch; Sean M Grimmond; James M Flanagan; Kumkum Khanna; Peter T Simpson; Sunil R Lakhani; Georgia Chenevix-Trench
Subtypes of familial breast tumours revealed by expression and copy number profiling.
Breast cancer research and treatment 2010;123(3):661-77.
2010: Marielle W G Ruijs; Senno Verhoef; Matti A Rookus; Roelof Pruntel; Annemarie H Van Der Hout; Frans B L Hogervorst; Irma Kluijt; Rolf Sijmons; Cora M Aalfs; Anja Wagner; Margreet G E M Ausems; Nicoline Hoogerbrugge; Christi J van Asperen; Encarna B Gomez Garcia; Hanne Meijers-Heijboer; Leo P Ten Kate; Fred H Menko; Laura J van 't Veer
TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.
Journal of medical genetics 2010;47(6):421-8.
2010: Els van Riel; Margreet G E M Ausems; Frans B L Hogervorst; Irma Kluijt; Marielle E van Gijn; Jeanne van Echtelt; Karen Scheidel-Jacobse; Eric Fam Hennekam; Rein P Stulp; Yvonne J Vos; G Johan A Offerhaus; Fred H Menko; Johan Jp Gille
A novel pathogenic MLH1 missense mutation, c.112A > C, p.Asn38His, in six families with Lynch syndrome.
Hereditary cancer in clinical practice 2010;8(1):7.
2009: Simon A Joosse; Erik H van Beers; Ivon H G Tielen; Hugo Horlings; Johannes L Peterse; Nicoline Hoogerbrugge; M J L Ligtenberg; Lodewyk F A Wessels; Priscilla Axwijk; Senno Verhoef; Frans B L Hogervorst; petra nederlof
Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH.
Breast cancer research and treatment 2009;116(3):479-89.
2008: Amanda B Spurdle; Fergus J. Couch; Frans B L Hogervorst; Paolo Radice; Olga M Sinilnikova
Prediction and assessment of splicing alterations: implications for clinical testing.
Human mutation 2008;29(11):1304-13.
2008: Robert M W Hofstra; Amanda B Spurdle; Diana Eccles; William D Foulkes; Niels De Wind; Nicoline Hoogerbrugge; Frans B L Hogervorst
Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance.
Human mutation 2008;29(11):1292-303.
2008: Sharon E Plon; Diana M Eccles; Douglas Easton; William D Foulkes; Maurizio Genuardi; Marc S Greenblatt; Frans B L Hogervorst; Nicoline Hoogerbrugge; Amanda B Spurdle; Sean V Tavtigian
Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results.
Human mutation 2008;29(11):1282-91.
2008: Annegien Broeks; Linde M Braaf; Angelina Huseinovic; Marjanka K Schmidt; Nicola S Russell; Flora E van Leeuwen; Frans B L Hogervorst; Laura J van 't Veer
The spectrum of ATM missense variants and their contribution to contralateral breast cancer.
Breast cancer research and treatment 2008;107(2):243-8.
2007: Marjanka K Schmidt; Scarlett Reincke; Annegien Broeks; Linde M Braaf; Frans B L Hogervorst; R A E M Tollenaar; Nichola Johnson; Olivia Fletcher; Julian Peto; Johanna Tommiska; Carl Blomqvist; Heli Nevanlinna; Catherine S Healey; Alison M Dunning; Paul D P Pharoah; Douglas F Easton; Thilo Dörk; Laura J van't Veer
Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.
Cancer research 2007;67(19):9584-90.
2007: Annegien Broeks; Linde M Braaf; Angelina Huseinovic; Anke Nooijen; Jos H M Urbanus; Frans B L Hogervorst; Marjanka K Schmidt; Jan G M Klijn; Nicola S Russell; Flora E van Leeuwen; Laura J van 't Veer
Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study.
Breast cancer research : BCR 2007;9(2):R26.
2006: Annemarie H Van Der Hout; Ans M W van den Ouweland; Rob B van der Luijt; Hans J P Gille; Daniëlle Bodmer; Hennie T Brüggenwirth; Inge M Mulder; Pieter van der Vlies; Peter Elfferich; Maarten Huisman; Annelies M ten Berge; Joan Kromosoeto; Rumo P M Jansen; Patrick H A van Zon; Thyrsa Vriesman; Neeltje J W Arts; Majella Boutmy-de Lange; Jan C Oosterwijk; Hanne Meijers-Heijboer; Margreet G E M Ausems; Nicoline Hoogerbrugge; Senno Verhoef; D J J Halley; Yvonne J Vos; Frans B L Hogervorst; M J L Ligtenberg; Robert M W Hofstra
A DGGE system for comprehensive mutation screening of BRCA1 and BRCA2: application in a Dutch cancer clinic setting.
Human mutation 2006;27(7):654-66.
2006: Lili Li; Susan McVety; Rami Younan; Ping Liang; Desirée Du Sart; Philip H Gordon; Pierre Hutter; Frans B L Hogervorst; George Chong; William D Foulkes
Distinct patterns of germ-line deletions in MLH1 and MSH2: the implication of Alu repetitive element in the genetic etiology of Lynch syndrome (HNPCC).
Human mutation 2006;27(4):388.
2006: Renée C Niessen; Rolf Sijmons; Jianghua Ou; Sandra G M Olthof; Jan Osinga; M J L Ligtenberg; Frans B L Hogervorst; Janneke Weiss; Carli Tops; Frederik J Hes; Geertruida H de Bock; Charles H C M Buys; Jan H Kleibeuker; Robert M W Hofstra
MUTYH and the mismatch repair system: partners in crime?
Human genetics 2006;119(1-2):206-11.
2006: erik van beers; S A Joosse; M J L Ligtenberg; R Fles; Frans B L Hogervorst; Senno Verhoef; petra nederlof
A multiplex PCR predictor for aCGH success of FFPE samples.
British journal of cancer 2006;94(2):333-7.
2006: Teresa M Rudkin; Nancy Hamel; Maria Galvez; Frans B L Hogervorst; Johan J P Gille; Pål Møller; Jaran Apold; William D Foulkes
The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations.
BMC medical genetics 2006;7():15.
2005: Christi J van Asperen; Richard Brohet; E Johanna Meijers-Heijboer; Nicoline Hoogerbrugge; Senno Verhoef; H F A Vasen; Margreet G E M Ausems; Fred H Menko; E B Gomez Garcia; Jan G M Klijn; Frans B L Hogervorst; Johannes C van Houwelingen; Laura J van't Veer; Matti A Rookus; Flora E van Leeuwen
Cancer risks in BRCA2 families: estimates for sites other than breast and ovary.
Journal of medical genetics 2005;42(9):711-9.
2005: erik van beers; Tibor van Welsem; Lodewyk F A Wessels; Yunlei Li; Rogier A Oldenburg; Peter Devilee; Cees J Cornelisse; Senno Verhoef; Frans B L Hogervorst; Laura J van't Veer; petra nederlof
Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.
Cancer research 2005;65(3):822-7.
2003: Frans B L Hogervorst; petra nederlof; Johan J P Gille; Cathal J McElgunn; Maartje Grippeling; Roelof Pruntel; Rein Regnerus; Tibor van Welsem; Rosalina Spaendonk; Fred H Menko; Irma Kluijt; Charlotte Dommering; Senno Verhoef; Jan P Schouten; Laura J van't Veer; Gerard Pals
Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method.
Cancer research 2003;63(7):1449-53.
2002: Johan J P Gille; Frans B L Hogervorst; Gerard Pals; Juul Wijnen; R J van Schooten; Charlotte Dommering; Gerrit A Meijer; Mikael E Craanen; petra nederlof; Daphne de Jong; Cathal J McElgunn; Jan P Schouten; Fred H Menko
Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach.
British journal of cancer 2002;87(8):892-7.
1999: M J L Ligtenberg; Frans B L Hogervorst; H W Willems; PJ Arts; G Brink; S Hageman; E A Bosgoed; E van der Looij; Matti A Rookus; Peter Devilee; E M Vos; G Wigbout; P M Struycken; Fred H Menko; E J Th Rutgers; Lies Hoefsloot; E C Mariman; Han G Brunner; Laura J van 't Veer
Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2.
British journal of cancer 1999;79(9-10):1475-8.
1997: A Petrij-Bosch; T Peelen; Marcel van Vliet; Ronald van Eijk; R Olmer; M Drüsedau; Frans B L Hogervorst; S Hageman; PJ Arts; M J L Ligtenberg; Hanne Meijers-Heijboer; Jan G M Klijn; H F A Vasen; Cees J Cornelisse; Laura J van 't Veer; Egbert Bakker; Gert-Jan B van Ommen; Peter Devilee
BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients.
Nature genetics 1997;17(3):341-5.
1997: T Peelen; Marcel van Vliet; A Petrij-Bosch; R Mieremet; C Szabo; Ans M W van den Ouweland; Frans B L Hogervorst; Richard Brohet; M J L Ligtenberg; E Teugels; Rob B van der Luijt; Annemarie H Van Der Hout; Johan J P Gille; Gerard Pals; Inge Jedema; R Olmer; Inge van Leeuwen; B Newman; M Plandsoen; M van der Est; G Brink; S Hageman; PJ Arts; M M Bakker; Peter Devilee
A high proportion of novel mutations in BRCA1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families.
American journal of human genetics 1997;60(5):1041-9.
1996: P A Roest; M Bout; A C van der Tuijn; I B Ginjaar; Egbert Bakker; Frans B L Hogervorst; Gert-Jan B van Ommen; Johan T den Dunnen
Splicing mutations in DMD/BMD detected by RT-PCR/PTT: detection of a 19AA insertion in the cysteine rich domain of dystrophin compatible with BMD.
Journal of medical genetics 1996;33(11):935-9.
1996: G O Delwel; Frans B L Hogervorst; Arnoud Sonnenberg
Cleavage of the alpha6A subunit is essential for activation of the alpha6Abeta1 integrin by phorbol 12-myristate 13-acetate.
The Journal of biological chemistry 1996;271(13):7293-6.
1995: Frans B L Hogervorst; R S Cornelis; M Bout; Marcel van Vliet; Jan C Oosterwijk; R Olmer; B Bakker; J G Klijn; H F A Vasen; H Meijers-Heijboer
Rapid detection of BRCA1 mutations by the protein truncation test.
Nature genetics 1995;10(2):208-12.
1995: J C Heikoop; Frans B L Hogervorst; E J Meershoek; P M Grootscholten; Johan T den Dunnen; Gert-Jan B van Ommen
Expression of the human Dp 71 (apo-dystrophin-1) gene from a 760-kb DMD-YAC transferred to mouse cells.
European journal of human genetics : EJHG 1995;3(3):168-79.
1994: CM Niessen; Frans B L Hogervorst; L H Jaspars; Annemieke A de Melker; G O Delwel; E H Hulsman; Ingrid Kuikman; Arnoud Sonnenberg
The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin.
Experimental cell research 1994;211(2):360-7.
1994: G O Delwel; Annemieke A de Melker; Frans B L Hogervorst; L H Jaspars; D L Fles; Ingrid Kuikman; A Lindblom; M Paulsson; R Timpl; Arnoud Sonnenberg
Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms.
Molecular biology of the cell 1994;5(2):203-15.
1993: G O Delwel; Frans B L Hogervorst; Ingrid Kuikman; M Paulsson; R Timpl; Arnoud Sonnenberg
Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin.
The Journal of biological chemistry 1993;268(34):25865-75.
1993: Frans B L Hogervorst; Ingrid Kuikman; E Noteboom; Arnoud Sonnenberg
The role of phosphorylation in activation of the alpha 6A beta 1 laminin receptor.
The Journal of biological chemistry 1993;268(25):18427-30.
1993: B P Hierck; Sólveig Thorsteinsdóttir; CM Niessen; E Freund; L V Iperen; A Feyen; Frans B L Hogervorst; Robert E Poelmann; C L Mummery; Arnoud Sonnenberg
Variants of the alpha 6 beta 1 laminin receptor in early murine development: distribution, molecular cloning and chromosomal localization of the mouse integrin alpha 6 subunit.
Cell adhesion and communication 1993;1(1):33-53.
1993: Frans B L Hogervorst; L G Admiraal; CM Niessen; Ingrid Kuikman; Hans Janssen; H Daams; Arnoud Sonnenberg
Biochemical characterization and tissue distribution of the A and B variants of the integrin alpha 6 subunit.
The Journal of cell biology 1993;121(1):179-91.
1991: Frans B L Hogervorst; Ingrid Kuikman; A G van Kessel; Arnoud Sonnenberg
Molecular cloning of the human alpha 6 integrin subunit. Alternative splicing of alpha 6 mRNA and chromosomal localization of the alpha 6 and beta 4 genes.
European journal of biochemistry / FEBS 1991;199(2):425-33.
1991: Yvette van Kooyk; P Weder; Frans B L Hogervorst; Arthur J Verhoeven; Gijs A van Seventer; Anje A Te Velde; Jannie Borst; G D Keizer; Carl G Figdor
Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion.
The Journal of cell biology 1991;112(2):345-54.
1990: Frans B L Hogervorst; Ingrid Kuikman; A E von dem Borne; Arnoud Sonnenberg
Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain.
The EMBO journal 1990;9(3):765-70.
1989: Steven T Pals; Frans B L Hogervorst; G D Keizer; T Thepen; E Horst; Carl Figdor
Identification of a widely distributed 90-kDa glycoprotein that is homologous to the Hermes-1 human lymphocyte homing receptor.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(3):851-7.
1988: Arnoud Sonnenberg; Frans B L Hogervorst; A Osterop; F E Veltman
Identification and characterization of a novel antigen complex on mouse mammary tumor cells using a monoclonal antibody against platelet glycoprotein Ic.
The Journal of biological chemistry 1988;263(28):14030-8.
1987: Arnoud Sonnenberg; Hans Janssen; Frans B L Hogervorst; Jero Calafat; J Hilgers
A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody.
The Journal of biological chemistry 1987;262(21):10376-83.