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Petter Höglund

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Michal Sternberg-Simon; Björn Onfelt; Yishai Pickman; Petter Brodin; Petter Höglund; Klas Kärre; Karl-Johan Malmberg; Ramit Mehr
Natural killer cell inhibitory receptor expression in humans and mice: a closer look.
Åsa Ingvar; Rino Bellocco; Pia Fernberg; Petter Höglund; Bernt Lindelöf; Gunnar Tufveson; Karin Ekström Smedby; Johanna Adami
No association between infections, HLA type and other transplant-related factors and risk of cutaneous squamous cell carcinoma in solid organ transplant recipients.
Petter Brodin; Klas Kärre; Tadepally Lakshmikanth; Petter Höglund
Skewing of the NK cell repertoire by MHC class I via quantitatively controlled enrichment and contraction of specific Ly49 subsets.

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All Publications

2013: Michal Sternberg-Simon; Björn Onfelt; Yishai Pickman; Petter Brodin; Petter Höglund; Klas Kärre; Karl-Johan Malmberg; Ramit Mehr
Natural killer cell inhibitory receptor expression in humans and mice: a closer look.
Frontiers in immunology 2013;4():65.
2012: Åsa Ingvar; Rino Bellocco; Pia Fernberg; Petter Höglund; Bernt Lindelöf; Gunnar Tufveson; Karin Ekström Smedby; Johanna Adami
No association between infections, HLA type and other transplant-related factors and risk of cutaneous squamous cell carcinoma in solid organ transplant recipients.
Acta dermato-venereologica 2012;92(6):609-14.
2012: Petter Brodin; Klas Kärre; Tadepally Lakshmikanth; Petter Höglund
Skewing of the NK cell repertoire by MHC class I via quantitatively controlled enrichment and contraction of specific Ly49 subsets.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(5):2218-26.
2011: Asya Kaplan; Refael Kohen; Karsten Köhler; Shulamit Kotzer; Catarina R Almeida; Daniel M Davis; Gilad Halpert; Petter Höglund; Mali Salmon-Divon; Ramit Mehr
Simulations of the NK cell immune synapse reveal that activation thresholds can be established by inhibitory receptors acting locally.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(2):760-73.
2010: Petter Höglund; Petter Brodin
Current perspectives of natural killer cell education by MHC class I molecules.
Nature reviews. Immunology 2010;10(10):724-34.
2010: Emma Lindh; Eleftheria Rosmaraki; Louise Berg; Hanna Brauner; Mikael C I Karlsson; Leena Peltonen; Petter Höglund; Ola Winqvist
AIRE deficiency leads to impaired iNKT cell development.
Journal of autoimmunity 2010;34(1):66-72.
2010: Petter Brodin; Tadepally Lakshmikanth; Ramit Mehr; MH Johansson; Adil Doganay Duru; Adnane Achour; Mali Salmon-Divon; Klas Kärre; Petter Höglund; Sofia Johansson
Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice.
PloS one 2010;5(10):.
2009: Petter Brodin; Klas Kärre; Petter Höglund
NK cell education: not an on-off switch but a tunable rheostat.
Trends in immunology 2009;30(4):143-9.
2009: Sofia Johansson; Mali Salmon-Divon; MH Johansson; Yishai Pickman; Petter Brodin; Klas Kärre; Ramit Mehr; Petter Höglund
Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice.
PloS one 2009;4(6):e6046.
2008: Petter Brodin; Petter Höglund
Beyond licensing and disarming: a quantitative view on NK-cell education.
European journal of immunology 2008;38(11):2934-7.
2008: Håkan T L Hall; Hanna Sjölin; Hanna Brauner; Elena Tomasello; Marc Dalod; Eric Vivier; Petter Höglund
Increased diabetes development and decreased function of CD4+CD25+ Treg in the absence of a functional DAP12 adaptor protein.
European journal of immunology 2008;38(11):3191-9.
2008: Jelena Petrovic Berglund; Jelena Petrovc Berglund; Maria Encarnita Mariotti-Ferrandiz; Eleftheria Rosmaraki; Håkan Hall; Pierre-André Cazenave; Adrien Six; Petter Höglund
TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation.
Molecular immunology 2008;45(11):3059-64.
2006: Hanna Sjölin; Scott H Robbins; Gilles Bessou; Asa S Hidmark; Elena Tomasello; Maria Johansson; Håkan Hall; Férose Charifi; Gunilla B Karlsson Hedestam; Christine A Biron; Klas Kärre; Petter Höglund; Eric Vivier; Marc Dalod
DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):2908-16.
2006: Petter Höglund
Induced peripheral regulatory T cells: the family grows larger.
European journal of immunology 2006;36(2):264-6.
2006: Petter Höglund
DNA damage and tumor surveillance: one trigger for two pathways.
Science's STKE : signal transduction knowledge environment 2006;2006(317):pe2.
2005: Sofia Johansson; Louise Berg; Håkan Hall; Petter Höglund
NK cells: elusive players in autoimmunity.
Trends in immunology 2005;26(11):613-8.
2005: Sofia Johansson; Maria Johansson; Eleftheria Rosmaraki; Gustaf Vahlne; Ramit Mehr; Mali Salmon-Divon; François Lemonnier; Klas Kärre; Petter Höglund
Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules.
The Journal of experimental medicine 2005;201(7):1145-55.
2005: Mali Salmon-Divon; Petter Höglund; Maria H Johansson; Sofia Johansson; Ramit Mehr
Computational modeling of human natural killer cell development suggests a selection process regulating coexpression of KIR with CD94/NKG2A.
Molecular immunology 2005;42(4):397-403.
2004: Håkan T L Hall; Jelena Petrovic; Petter Höglund
Reduced antigen concentration and costimulatory blockade increase IFN-gamma secretion in naive CD8+ T cells.
European journal of immunology 2004;34(11):3091-101.
2004: Jelena Petrovic; H Hall; Ramit Mehr; Rickard Glas; Petter Höglund
Inhibition of the proteasome reduces transfer-induced diabetes in nonobese diabetic mice.
Scandinavian journal of immunology 2004;60(1-2):134-42.
2004: Linda Oberg; Sofia Johansson; Jakob Michaëlsson; Elena Tomasello; Eric Vivier; Klas Kärre; Petter Höglund
Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo - role of KARAP/DAP12-dependent and -independent pathways.
European journal of immunology 2004;34(6):1646-53.
2004: MH Johansson; Petter Höglund
Low number of H-2Dd-negative haematopoietic cells in mixed bone marrow chimeras convey in vivo tolerance to H-2Dd-negative cells but fail to prevent resistance to H-2Dd-negative leukaemia.
Scandinavian journal of immunology 2004;59(1):71-8.
2004: Sofia Johansson; Håkan Hall; Jens Björklund; Petter Höglund
Broadly impaired NK cell function in non-obese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro.
International immunology 2004;16(1):1-11.
2003: Petter Höglund; Klas Kärre; Georg Klein
The uterine cervix--a new member of the family of immunologically exceptional sites?
Cancer immunity 2003;3():6.
2003: Mali Salmon-Divon; Petter Höglund; Ramit Mehr
Models for natural killer cell repertoire formation.
Clinical & developmental immunology 2003;10(2-4):183-92.
2003: Mali Salmon-Divon; Petter Höglund; Ramit Mehr
Generation of the natural killer cell repertoire: the sequential vs. the two-step selection model.
Bulletin of mathematical biology 2003;65(2):199-218.
2001: A Sjöström; M Eriksson; Cristina Cerboni; MH Johansson; charles sentman; Klas Kärre; Petter Höglund
Acquisition of external major histocompatibility complex class I molecules by natural killer cells expressing inhibitory Ly49 receptors.
The Journal of experimental medicine 2001;194(10):1519-30.
2000: MH Johansson; Charles J Bieberich; A Kâse-Sjöström; T Yoshioka; E Höglund; Barbara Christy; G Scangos; Klas Kärre; G Jay; Petter Höglund
Differential effects on T cell and NK cell development by tissue-specific expression of H-2D(d) transgene.
European journal of immunology 2000;30(2):525-33.
1999: J Lindberg; A Martín-Fontecha; Petter Höglund
Natural killing of MHC class I(-) lymphoblasts by NK cells from long-term bone marrow culture requires effector cell expression of Ly49 receptors.
International immunology 1999;11(8):1239-46.
1998: MH Johansson; E Höglund; Mary C Nakamura; James C Ryan; Petter Höglund
Alpha1/alpha2 domains of H-2D(d), but not H-2L(d), induce "missing self" reactivity in vivo--no effect of H-2L(d) on protection against NK cells expressing the inhibitory receptor Ly49G2.
European journal of immunology 1998;28(12):4198-206.
1998: A Kåse; MH Johansson; MY Olsson-Alheim; Klas Kärre; Petter Höglund
External and internal calibration of the MHC class I-specific receptor Ly49A on murine natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6133-8.
1998: Petter Höglund; Rickard Glas; C Ménard; A Kåse; MH Johansson; L Franksson; F Lemmonier; Klas Kärre
Beta2-microglobulin-deficient NK cells show increased sensitivity to MHC class I-mediated inhibition, but self tolerance does not depend upon target cell expression of H-2Kb and Db heavy chains.
European journal of immunology 1998;28(1):370-8.
1997: MH Johansson; Charles J Bieberich; G Jay; Klas Kärre; Petter Höglund
Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene.
The Journal of experimental medicine 1997;186(3):353-64.
1997: Petter Höglund; Jonas Sundbäck; MY Olsson-Alheim; M Johansson; M Salcedo; Claes Ohlén; Hans-Gustaf Ljunggren; charles sentman; Klas Kärre
Host MHC class I gene control of NK-cell specificity in the mouse.
Immunological reviews 1997;155():11-28.
1997: Petter Höglund; MY Olsson-Alheim; M Johansson; Klas Kärre; charles sentman
Lack of F1 anti-parental resistance in H-2b/d F1 hybrids devoid of beta2-microglobulin.
European journal of immunology 1997;27(1):342-5.
1995: M Salcedo; Petter Höglund; Hans-Gustaf Ljunggren
Natural killer cell interaction with murine allogeneic MHC class I molecules.
Transplantation 1995;60(3):281-6.
1995: C Ohlén; Petter Höglund; charles sentman; Ennio Carbone; Hans-Gustaf Ljunggren; Beverly H Koller; Klas Kärre
Inhibition of natural killer cell-mediated bone marrow graft rejection by allogeneic major histocompatibility complex class I, but not class II molecules.
European journal of immunology 1995;25(5):1286-91.
1995: Rickard Glas; M Waldenström; Petter Höglund; George Klein; Klas Kärre; Hans-Gustaf Ljunggren
Rejection of tumors in mice with severe combined immunodeficiency syndrome determined by the major histocompatibility complex. Class I expression on the graft.
Cancer research 1995;55(9):1911-6.
1994: charles sentman; M Y Olsson; M Salcedo; Petter Höglund; U Lendahl; K Käre
H-2 allele-specific protection from NK cell lysis in vitro for lymphoblasts but not tumor targets. Protection mediated by alpha 1/alpha 2 domains.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5482-90.
1994: Rickard Glas; C Ohlén; Petter Höglund; Klas Kärre
The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I.
The Journal of experimental medicine 1994;179(2):661-72.
1993: Petter Höglund; M Waldenström; Klas Kärre
Role of major histocompatibility complex class I alpha 1/alpha 2 domain polymorphism and in vivo expression pattern in tumor resistance: studies with transgenic mice and lymphoma cell transfectants.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(3):175-81.
1992: Rickard Glas; L Franksson; C Ohlén; Petter Höglund; Beverly H Koller; Hans-Gustaf Ljunggren; Klas Kärre
Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11381-5.
1992: G Stuber; Susanne Modrow; Petter Höglund; L Franksson; J Elvin; Hans Wolf; Klas Kärre; George Klein
Assessment of major histocompatibility complex class I interaction with Epstein-Barr virus and human immunodeficiency virus peptides by elevation of membrane H-2 and HLA in peptide loading-deficient cells.
European journal of immunology 1992;22(10):2697-703.
1991: Petter Höglund; C Ohlén; Ennio Carbone; L Franksson; Hans-Gustaf Ljunggren; A Latour; Beverly H Koller; Klas Kärre
Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10332-6.
1991: Fumie Aosai; C Ohlen; Hans-Gustaf Ljunggren; Petter Höglund; L Franksson; H Ploegh; A Townsend; Klas Kärre; Hans J Stauss
Different types of allospecific CTL clones identified by their ability to recognize peptide loading-defective target cells.
European journal of immunology 1991;21(11):2767-74.
1991: Petter Höglund; Rickard Glas; C Ohlén; Hans-Gustaf Ljunggren; Klas Kärre
Alteration of the natural killer repertoire in H-2 transgenic mice: specificity of rapid lymphoma cell clearance determined by the H-2 phenotype of the target.
The Journal of experimental medicine 1991;174(2):327-34.
1991: Hans-Gustaf Ljunggren; C Ohlén; Petter Höglund; L Franksson; Klas Kärre
The RMA-S lymphoma mutant; consequences of a peptide loading defect on immunological recognition and graft rejection.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1991;6():38-44.
1990: Hans-Gustaf Ljunggren; N J Stam; C Ohlén; Jacques Neefjes; Petter Höglund; M T Heemels; J Bastin; Schumacher Ton; A Townsend; Klas Kärre
Empty MHC class I molecules come out in the cold.
Nature 1990;346(6283):476-80.
1990: Petter Höglund; Hans-Gustaf Ljunggren; Klas Kärre; G Jay
Role of major histocompatibility complex class-I molecules in tumor rejection. New insights from studies with synthetic peptides and transgenic mice.
Immunologic research 1990;9(4):298-313.
1989: C Ohlén; G Kling; Petter Höglund; M Hansson; G Scangos; Charles J Bieberich; G Jay; Klas Kärre
Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice.
Science (New York, N.Y.) 1989;246(4930):666-8.
1988: Petter Höglund; Hans-Gustaf Ljunggren; C Ohlén; Lars Ahrlund-Richter; G Scangos; Charles J Bieberich; G Jay; George Klein; Klas Kärre
Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice.
The Journal of experimental medicine 1988;168(4):1469-74.
1988: T Yamasaki; George Klein; Hans-Gustaf Ljunggren; Petter Höglund; C Ohlén; M G Petersson; Klas Kärre
Effects of dimethyl sulfoxide treatment on H-2 expression and susceptibility to NK- or cytotoxic T-lymphocyte-mediated lysis of the YAC-1 lymphoma and its beta 2-microglobulin-deficient variant.
Journal of the National Cancer Institute 1988;80(4):263-9.
1988: Hans-Gustaf Ljunggren; C Ohlén; Petter Höglund; T Yamasaki; George Klein; Klas Kärre
Afferent and efferent cellular interactions in natural resistance directed against MHC class I deficient tumor grafts.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(2):671-8.