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TC Hohman

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TOP 3
TC Hohman; Mary A Cotter; Norman E Cameron
ATP-sensitive K(+) channel effects on nerve function, Na(+), K(+) ATPase, and glutathione in diabetic rats.
JP Glover; JL Jacot; MD Basso; TC Hohman; W Gerald Robison
Retinal capillary dilation: early diabetic-like retinopathy in the galactose-fed rat model.
S B Singh; M S Malamas; TC Hohman; Ramaswamy Nilakantan; Deborah A Carper; D Kitchen
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.

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All Publications

2000: TC Hohman; Mary A Cotter; Norman E Cameron
ATP-sensitive K(+) channel effects on nerve function, Na(+), K(+) ATPase, and glutathione in diabetic rats.
European journal of pharmacology 2000;397(2-3):335-41.
2000: JP Glover; JL Jacot; MD Basso; TC Hohman; W Gerald Robison
Retinal capillary dilation: early diabetic-like retinopathy in the galactose-fed rat model.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2000;16(2):167-72.
2000: S B Singh; M S Malamas; TC Hohman; Ramaswamy Nilakantan; Deborah A Carper; D Kitchen
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.
Journal of medicinal chemistry 2000;43(6):1062-70.
1999: Norman E Cameron; Mary A Cotter; Alison M Jack; MD Basso; TC Hohman
Protein kinase C effects on nerve function, perfusion, Na(+), K(+)-ATPase activity and glutathione content in diabetic rats.
Diabetologia 1999;42(9):1120-30.
1998: TC Hohman; Ossama El-Kabbani; M S Malamas; K Lai; T Putilina; MH McGowan; Y Q Wane; Deborah A Carper
Probing the inhibitor-binding site of aldose reductase with site-directed mutagenesis.
European journal of biochemistry / FEBS 1998;256(2):310-6.
1998: W Gerald Robison; JL Jacot; JP Glover; MD Basso; TC Hohman
Diabetic-like retinopathy: early and late intervention therapies in galactose-fed rats.
Investigative ophthalmology & visual science 1998;39(10):1933-41.
1998: Denis Raccah; Thierry C Coste; Norman E Cameron; D Dufayet; Philippe Vague; TC Hohman
Effect of the aldose reductase inhibitor tolrestat on nerve conduction velocity, Na/K ATPase activity, and polyols in red blood cells, sciatic nerve, kidney cortex, and kidney medulla of diabetic rats.
Journal of diabetes and its complications 1998;12(3):154-62.
1998: Mary A Cotter; Norman E Cameron; TC Hohman
Correction of nerve conduction and endoneurial blood flow deficits by the aldose reductase inhibitor, tolrestat, in diabetic rats.
Journal of the peripheral nervous system : JPNS 1998;3(3):217-23.
1997: Norman E Cameron; Mary A Cotter; M Basso; TC Hohman
Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats.
Diabetologia 1997;40(3):271-81.
1996: W G Robinson; N M Laver; JL Jacot; JP Glover; M D Basso; P Blouin; TC Hohman
Diabetic-like retinopathy ameliorated with the aldose reductase inhibitor WAY-121,509.
Investigative ophthalmology & visual science 1996;37(6):1149-56.
1996: Norman E Cameron; Mary A Cotter; TC Hohman
Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats.
Diabetologia 1996;39(2):172-82.
1996: Norman E Cameron; Mary A Cotter; K C Dines; TC Hohman
Reversal of defective peripheral nerve conduction velocity, nutritive endoneurial blood flow, and oxygenation by a novel aldose reductase inhibitor, WAY-121,509, in streptozotocin-induced diabetic rats.
Journal of diabetes and its complications 1996;10(1):43-53.
1996: D Dvornik; TC Hohman; M D Basso
Aminoguanidine does not inhibit aldose reductase activity in galactose-fed rats.
Journal of diabetes and its complications 1996;10(1):23-30.
1995: Deborah A Carper; TC Hohman; S E Old
Residues affecting the catalysis and inhibition of rat lens aldose reductase.
Biochimica et biophysica acta 1995;1246(1):67-73.
1995: S E Old; Deborah A Carper; TC Hohman
Na,K-ATPase response to osmotic stress in primary dog lens epithelial cells.
Investigative ophthalmology & visual science 1995;36(1):88-94.
1994: M Kamijo; M Basso; P V Cherian; TC Hohman; Anders A F Sima
Galactosemia produces ARI-preventable nodal changes similar to those of diabetic neuropathy.
Diabetes research and clinical practice 1994;25(2):117-29.
1994: M S Malamas; TC Hohman
N-substituted spirosuccinimide, spiropyridazine, spiroazetidine, and acetic acid aldose reductase inhibitors derived from isoquinoline-1,3-diones. 2.
Journal of medicinal chemistry 1994;37(13):2059-70.
1994: M S Malamas; TC Hohman; J Millen
Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1.
Journal of medicinal chemistry 1994;37(13):2043-58.
1993: Anders A F Sima; Douglas A Greene; M B Brown; TC Hohman; D Hicks; G J Graepel; W J Bochenek; M Beg; B Gonen
Effect of hyperglycemia and the aldose reductase inhibitor tolrestat on sural nerve biochemistry and morphometry in advanced diabetic peripheral polyneuropathy. The Tolrestat Study Group.
Journal of diabetes and its complications 1993;7(3):157-69.
1992: Jay Wrobel; A Dietrich; S A Woolson; J Millen; M McCaleb; M C Harrison; TC Hohman; Janet Sredy; D Sullivan
Novel spirosuccinimides with incorporated isoindolone and benzisothiazole 1,1-dioxide moieties as aldose reductase inhibitors and antihyperglycemic agents.
Journal of medicinal chemistry 1992;35(24):4613-27.
1992: S Dasgupta; TC Hohman; Deborah A Carper
Hypertonic stress induces alpha B-crystallin expression.
Experimental eye research 1992;54(3):461-70.
1991: MICHAEL MCCALEB; M L McKean; TC Hohman; N Laver; W Gerald Robison
Intervention with the aldose reductase inhibitor, tolrestat, in renal and retinal lesions of streptozotocin-diabetic rats.
Diabetologia 1991;34(10):695-701.
1991: TC Hohman; Deborah A Carper; S Dasgupta; M Kaneko
Osmotic stress induces aldose reductase in glomerular endothelial cells.
Advances in experimental medicine and biology 1991;284():139-52.
1990: Deborah A Carper; M Kaneko; H Stark; TC Hohman
Increase in aldose reductase mRNA in dog lens epithelial cells under hypertonic conditions.
Experimental eye research 1990;50(6):743-9.
1990: M Kaneko; Deborah A Carper; C Nishimura; J Millen; M Bock; TC Hohman
Induction of aldose reductase expression in rat kidney mesangial cells and Chinese hamster ovary cells under hypertonic conditions.
Experimental cell research 1990;188(1):135-40.
1989: W Gerald Robison; M Nagata; N Laver; TC Hohman; J H Kinoshita
Diabetic-like retinopathy in rats prevented with an aldose reductase inhibitor.
Investigative ophthalmology & visual science 1989;30(11):2285-92.
1989: M Nagata; TC Hohman; C Nishimura; C M Drea; C Oliver; W Gerald Robison
Polyol and vacuole formation in cultured canine lens epithelial cells.
Experimental eye research 1989;48(5):667-77.
1989: TC Hohman; C Nishimura; W Gerald Robison
Aldose reductase and polyol in cultured pericytes of human retinal capillaries.
Experimental eye research 1989;48(1):55-60.
1988: C Nishimura; C Graham; TC Hohman; M Nagata; W Gerald Robison; Deborah A Carper
Characterization of mRNA and genes for aldose reductase in rat.
Biochemical and biophysical research communications 1988;153(3):1051-9.
1987: Paul Russell; S O Meakin; TC Hohman; Lap-Chee Tsui; M L Breitman
Relationship between proteins encoded by three human gamma-crystallin genes and distinct polypeptides in the eye lens.
Molecular and cellular biology 1987;7(9):3320-3.