FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Nikki Holbrook

Research Profile

Living Beings

Rats

Chemicals & Drugs

Physiology

Concepts & Ideas

Molecular Sequence Data

Disorders

Oxidative Stress

Anatomy

Co-author Network

Publications

TOP 3
Wanli Smith; Darrell D Norton; Myriam Gorospe; Haibing Jiang; Shino Nemoto; Nikki J Holbrook; TOREN FINKEL; John W Kusiak
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Stefan M Schieke; Claudia von Montfort; Darius P Buchczyk; Andreas Timmer; Susanne Grether-Beck; Jean Krutmann; Nikki J Holbrook; Lars-Oliver Klotz
Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides.
Li Ji; Nikki J Holbrook
Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Nikki Holbrook (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2005: Wanli Smith; Darrell D Norton; Myriam Gorospe; Haibing Jiang; Shino Nemoto; Nikki J Holbrook; TOREN FINKEL; John W Kusiak
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
The Journal of cell biology 2005;169(2):331-9.
2004: Stefan M Schieke; Claudia von Montfort; Darius P Buchczyk; Andreas Timmer; Susanne Grether-Beck; Jean Krutmann; Nikki J Holbrook; Lars-Oliver Klotz
Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides.
Free radical research 2004;38(7):729-37.
2004: Li Ji; Nikki J Holbrook
Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress.
Experimental gerontology 2004;39(5):735-44.
2003: Li Ji; Nikki J Holbrook
Common mechanisms for declines in oxidative stress tolerance and proliferation with aging.
Free radical biology & medicine 2003;35(3):292-9.
2003: Shizuo Ikeyama; Xian-Tao Wang; Li Ji; Andrej Podlutsky; Jennifer L Martindale; Gertrude Kokkonen; Rika van Huizen; Myriam Gorospe; Nikki J Holbrook
Expression of the pro-apoptotic gene gadd153/chop is elevated in liver with aging and sensitizes cells to oxidant injury.
The Journal of biological chemistry 2003;278(19):16726-31.
2003: Rika van Huizen; Jennifer L Martindale; Myriam Gorospe; Nikki J Holbrook
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling.
The Journal of biological chemistry 2003;278(18):15558-64.
2003: Shizuo Ikeyama; Gertrude Kokkonen; Jennifer L Martindale; Xian-Tao Wang; Myriam Gorospe; Nikki J Holbrook
Effects of aging and calorie restriction of Fischer 344 rats on hepatocellular response to proliferative signals.
Experimental gerontology 2003;38(4):431-9.
2003: Sonsoles Shack; Xian-Tao Wang; Gertrude Kokkonen; Myriam Gorospe; Dan Longo; Nikki J Holbrook
Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity.
Molecular and cellular biology 2003;23(7):2407-14.
2002: Ollivier Milhavet; Jennifer L Martindale; Simonetta Camandola; Sic L Chan; Devin S Gary; Aiwu Cheng; Nikki J Holbrook; Mark P Mattson
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.
Journal of neurochemistry 2002;83(3):673-81.
2002: Nikki J Holbrook; Shizuo Ikeyama
Age-related decline in cellular response to oxidative stress: links to growth factor signaling pathways with common defects.
Biochemical pharmacology 2002;64(5-6):999-1005.
2002: Jennifer L Martindale; Nikki J Holbrook
Cellular response to oxidative stress: signaling for suicide and survival.
Journal of cellular physiology 2002;192(1):1-15.
2002: Olga Potapova; Sergey V Anisimov; Myriam Gorospe; Ryan H Dougherty; William A Gaarde; Kenneth R Boheler; Nikki J Holbrook
Targets of c-Jun NH(2)-terminal kinase 2-mediated tumor growth regulation revealed by serial analysis of gene expression.
Cancer research 2002;62(11):3257-63.
2002: Shizuo Ikeyama; Gertrude Kokkonen; Sonsoles Shack; Xian-Tao Wang; Nikki J Holbrook
Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(1):114-6.
2001: Wengong Wang; Xiaoling Yang; V J Cristofalo; Nikki J Holbrook; Myriam Gorospe
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence.
Molecular and cellular biology 2001;21(17):5889-98.
2001: Olga Potapova; S Basu; Dan Mercola; Nikki J Holbrook
Protective role for c-Jun in the cellular response to DNA damage.
The Journal of biological chemistry 2001;276(30):28546-53.
2001: Xian-Tao Wang; KD McCullough; X J Wang; G Carpenter; Nikki J Holbrook
Oxidative stress-induced phospholipase C-gamma 1 activation enhances cell survival.
The Journal of biological chemistry 2001;276(30):28364-71.
2001: T Buschmann; Olga Potapova; Anat Bar-Shira; Vladimir N Ivanov; Serge Y Fuchs; Scott Henderson; VA Fried; T Minamoto; Dania Alarcon-Vargas; Matthew R Pincus; William A Gaarde; Nikki J Holbrook; Yosef Shiloh; Ze'ev Ronai
Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.
Molecular and cellular biology 2001;21(8):2743-54.
2001: KD McCullough; Jennifer L Martindale; Lars-Oliver Klotz; T Y Aw; Nikki J Holbrook
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state.
Molecular and cellular biology 2001;21(4):1249-59.
2001: Lars-Oliver Klotz; Nikki J Holbrook; Helmut Sies
UVA and singlet oxygen as inducers of cutaneous signaling events.
Current problems in dermatology 2001;29():95-113.
2000: Xiantao Wang; Jennifer L Martindale; Nikki J Holbrook
Requirement for ERK activation in cisplatin-induced apoptosis.
The Journal of biological chemistry 2000;275(50):39435-43.
2000: E D Arrington; M Craig Caldwell; T Kumaravel; Althaf Lohani; A Joshi; Michele K Evans; H T Chen; A Nussenzweig; Nikki J Holbrook; Myriam Gorospe
Enhanced sensitivity and long-term G2 arrest in hydrogen peroxide-treated Ku80-null cells are unrelated to DNA repair defects.
Free radical biology & medicine 2000;29(11):1166-76.
2000: Lars-Oliver Klotz; Stefan M Schieke; Helmut Sies; Nikki J Holbrook
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.
The Biochemical journal 2000;352 Pt 1():219-25.
2000: S Lin; Wengong Wang; Gerald M Wilson; Xiaoling Yang; Gary Brewer; Nikki J Holbrook; Myriam Gorospe
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.
Molecular and cellular biology 2000;20(21):7903-13.
2000: Olga Potapova; Myriam Gorospe; Frédéric Bost; Nicholas Dean; William A Gaarde; Dan Mercola; Nikki J Holbrook
c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells.
The Journal of biological chemistry 2000;275(32):24767-75.
2000: Yanping Huang; Dorothy Hutter; Yusen Liu; Xiantao Wang; MS Sheikh; A M Chan; Nikki J Holbrook
Transforming growth factor-beta 1 suppresses serum deprivation-induced death of A549 cells through differential effects on c-Jun and JNK activities.
The Journal of biological chemistry 2000;275(24):18234-42.
2000: Xiantao Wang; KD McCullough; T F Franke; Nikki J Holbrook
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival.
The Journal of biological chemistry 2000;275(19):14624-31.
2000: Dorothy Hutter; Y Yo; W Chen; Pinghu Liu; Nikki J Holbrook; George S Roth; Yusen Liu
Age-related decline in Ras/ERK mitogen-activated protein kinase cascade is linked to a reduced association between Shc and EGF receptor.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(3):B125-34.
2000: Olga Potapova; Myriam Gorospe; R H Dougherty; Nicholas Dean; William A Gaarde; Nikki J Holbrook
Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner.
Molecular and cellular biology 2000;20(5):1713-22.
2000: Wengong Wang; Henry Furneaux; H Cheng; M Craig Caldwell; Dorothy Hutter; Yusen Liu; Nikki J Holbrook; Myriam Gorospe
HuR regulates p21 mRNA stabilization by UV light.
Molecular and cellular biology 2000;20(3):760-9.
1999: Sonsoles Shack; Myriam Gorospe; TW Fawcett; W R Hudgins; Nikki J Holbrook
Activation of the cholesterol pathway and Ras maturation in response to stress.
Oncogene 1999;18(44):6021-8.
1999: MS Sheikh; Yanping Huang; E A Fernandez-Salas; Wafik S El-Deiry; H Friess; Sally A Amundson; Jing Yin; Meltzer Stephen J.; Nikki J Holbrook; Albert J Fornace
The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract.
Oncogene 1999;18(28):4153-9.
1999: Yanping Huang; MS Sheikh; Albert J Fornace; Nikki J Holbrook
Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells.
Oncogene 1999;18(23):3431-9.
1999: TW Fawcett; Jennifer L Martindale; KZ Guyton; Tsonwin Hai; Nikki J Holbrook
Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response.
The Biochemical journal 1999;339 ( Pt 1)():135-41.
1999: Myriam Gorospe; J M Egan; Berton Zbar; M Lerman; Laura Geil; Igor Kuzmin; Nikki J Holbrook
Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells.
Molecular and cellular biology 1999;19(2):1289-300.
1999: Myriam Gorospe; X Wang; Nikki J Holbrook
Functional role of p21 during the cellular response to stress.
Gene expression 1999;7(4-6):377-85.
1998: W Chen; Jennifer L Martindale; Nikki J Holbrook; Yusen Liu
Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.
Molecular and cellular biology 1998;18(9):5178-88.
1998: KZ Guyton; Myriam Gorospe; Xiantao Wang; YD Mock; Gertrude Kokkonen; Yusen Liu; George S Roth; Nikki J Holbrook
Age-related changes in activation of mitogen-activated protein kinase cascades by oxidative stress.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(1):23-7.
1998: Xiantao Wang; Jennifer L Martindale; Yusen Liu; Nikki J Holbrook
The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival.
The Biochemical journal 1998;333 ( Pt 2)():291-300.
1998: Yusen Liu; Myriam Gorospe; Gertrude Kokkonen; Marvin O Boluyt; A Younes; YD Mock; Xiantao Wang; George S Roth; Nikki J Holbrook
Impairments in both p70 S6 kinase and extracellular signal-regulated kinase signaling pathways contribute to the decline in proliferative capacity of aged hepatocytes.
Experimental cell research 1998;240(1):40-8.
1998: Myriam Gorospe; X Wang; Nikki J Holbrook
p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system.
Molecular and cellular biology 1998;18(3):1400-7.
1998: D P Madio; Peter van Gelderen; D DesPres; A W Olson; Jacco A de Zwart; TW Fawcett; Nikki J Holbrook; M Mandel; Chrit T W Moonen
On the feasibility of MRI-guided focused ultrasound for local induction of gene expression.
Journal of magnetic resonance imaging : JMRI 1998;8(1):101-4.
1997: X Wang; Myriam Gorospe; Yanping Huang; Nikki J Holbrook
p27Kip1 overexpression causes apoptotic death of mammalian cells.
Oncogene 1997;15(24):2991-7.
1997: Curt D Wolfgang; B P Chen; Jennifer L Martindale; Nikki J Holbrook; Tsonwin Hai
gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.
Molecular and cellular biology 1997;17(11):6700-7.
1997: Q Xu; TW Fawcett; Myriam Gorospe; KZ Guyton; Yusen Liu; Nikki J Holbrook
Induction of mitogen-activated protein kinase phosphatase-1 during acute hypertension.
Hypertension 1997;30(1 Pt 1):106-11.
1997: TW Fawcett; Q Xu; Nikki J Holbrook
Potentiation of heat stress-induced hsp70 expression in vivo by aspirin.
Cell stress & chaperones 1997;2(2):104-9.
1997: Myriam Gorospe; corrado cirielli; Xiao-Jing Wang; P Seth; M C Capogrossi; Nikki J Holbrook
p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells.
Oncogene 1997;14(8):929-35.
1996: Myriam Gorospe; Sonsoles Shack; K Z Guyton; D Samid; Nikki J Holbrook
Up-regulation and functional role of p21Waf1/Cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(12):1609-15.
1996: Myriam Gorospe; Xiantao Wang; K Z Guyton; Nikki J Holbrook
Protective role of p21(Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells.
Molecular and cellular biology 1996;16(12):6654-60.
1996: H B Eastman; TW Fawcett; Robert Udelsman; Nikki J Holbrook
Effects of perturbations of the hypothalamic-pituitary-adrenal axis on the acute phase response: altered C/EBP and acute phase response gene expression in lipopolysaccharide-treated rats.
Shock (Augusta, Ga.) 1996;6(4):286-92.
1996: K Z Guyton; Myriam Gorospe; Thomas W Kensler; Nikki J Holbrook
Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion.
Cancer research 1996;56(15):3480-5.
1996: Q Xu; TW Fawcett; Robert Udelsman; Nikki J Holbrook
Activation of heat shock transcription factor 1 in rat aorta in response to high blood pressure.
Hypertension 1996;28(1):53-7.
1996: TW Fawcett; H B Eastman; Jennifer L Martindale; Nikki J Holbrook
Physical and functional association between GADD153 and CCAAT/enhancer-binding protein beta during cellular stress.
The Journal of biological chemistry 1996;271(24):14285-9.
1996: K Z Guyton; Q Xu; Nikki J Holbrook
Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element.
The Biochemical journal 1996;314 ( Pt 2)():547-54.
1996: Myriam Gorospe; Yusen Liu; Q Xu; Francis J Chrest; Nikki J Holbrook
Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2.
Molecular and cellular biology 1996;16(3):762-70.
1996: K Z Guyton; Yusen Liu; Myriam Gorospe; Q Xu; Nikki J Holbrook
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury.
The Journal of biological chemistry 1996;271(8):4138-42.
1996: Yusen Liu; K Z Guyton; Myriam Gorospe; Q Xu; Gertrude Kokkonen; Y D Mock; G S Roth; Nikki J Holbrook
Age-related decline in mitogen-activated protein kinase activity in epidermal growth factor-stimulated rat hepatocytes.
The Journal of biological chemistry 1996;271(7):3604-7.
1996: Myriam Gorospe; Nikki J Holbrook
Role of p21 in prostaglandin A2-mediated cellular arrest and death.
Cancer research 1996;56(3):475-9.
1996: Q Xu; Yusen Liu; Myriam Gorospe; Robert Udelsman; Nikki J Holbrook
Acute hypertension activates mitogen-activated protein kinases in arterial wall.
The Journal of clinical investigation 1996;97(2):508-14.
1996: Yusen Liu; K Z Guyton; Myriam Gorospe; Q Xu; J C Lee; Nikki J Holbrook
Differential activation of ERK, JNK/SAPK and P38/CSBP/RK map kinase family members during the cellular response to arsenite.
Free radical biology & medicine 1996;21(6):771-81.
1996: K Z Guyton; D R Spitz; Nikki J Holbrook
Expression of stress response genes GADD153, c-jun, and heme oxygenase-1 in H2O2- and O2-resistant fibroblasts.
Free radical biology & medicine 1996;20(5):735-41.
1996: Q Xu; L Ganju; TW Fawcett; Nikki J Holbrook
Vasopressin-induced heat shock protein expression in renal tubular cells.
Laboratory investigation; a journal of technical methods and pathology 1996;74(1):178-87.
1996: Yusen Liu; Jennifer L Martindale; Myriam Gorospe; Nikki J Holbrook
Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway.
Cancer research 1996;56(1):31-5.
1995: Q Xu; D G Li; Nikki J Holbrook; Robert Udelsman
Acute hypertension induces heat-shock protein 70 gene expression in rat aorta.
Circulation 1995;92(5):1223-9.
1995: Augustine M K Choi; Robert J Pignolo; Colette ApRhys; Vincent J Cristofalo; Nikki J Holbrook
Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: reduced AP-1 activation and collagenase gene expression.
Journal of cellular physiology 1995;164(1):65-73.
1995: Robert Udelsman; D G Li; C A Stagg; Nikki J Holbrook
Aortic crosstransplantation between young and old rats: effect upon the heat shock protein 70 stress response.
The journals of gerontology. Series A, Biological sciences and medical sciences 1995;50(4):B187-92.
1995: Augustine M K Choi; S Sylvester; Leo E Otterbein; Nikki J Holbrook
Molecular responses to hyperoxia in vivo: relationship to increased tolerance in aged rats.
American journal of respiratory cell and molecular biology 1995;13(1):74-82.
1995: S L Sylvester; Colette ApRhys; J D Luethy-Martindale; Nikki J Holbrook
Induction of GADD153, a CCAAT/enhancer-binding protein (C/EBP)-related gene, during the acute phase response in rats. Evidence for the involvement of C/EBPs in regulating its expression.
The Journal of biological chemistry 1995;270(24):14842.
1994: Augustine M K Choi; R W Tucker; S G Carlson; G Weigand; Nikki J Holbrook
Calcium mediates expression of stress-response genes in prostaglandin A2-induced growth arrest.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(13):1048-54.
1994: S L Sylvester; Colette ApRhys; J D Luethy-Martindale; Nikki J Holbrook
Induction of GADD153, a CCAAT/enhancer-binding protein (C/EBP)-related gene, during the acute phase response in rats. Evidence for the involvement of C/EBPs in regulating its expression.
The Journal of biological chemistry 1994;269(31):20119-25.
1994: Robert Udelsman; M J Blake; C A Stagg; Nikki J Holbrook
Endocrine control of stress-induced heat shock protein 70 expression in vivo.
Surgery 1994;115(5):611-6.
1994: J D Luethy; Nikki J Holbrook
The pathway regulating GADD153 induction in response to DNA damage is independent of protein kinase C and tyrosine kinases.
Cancer research 1994;54(7 Suppl):1902s-1906s.
1993: S G Carlson; TW Fawcett; J D Bartlett; Michel Bernier; Nikki J Holbrook
Regulation of the C/EBP-related gene gadd153 by glucose deprivation.
Molecular and cellular biology 1993;13(8):4736-44.
1993: Robert Udelsman; M J Blake; C A Stagg; D G Li; D J Putney; Nikki J Holbrook
Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response.
The Journal of clinical investigation 1993;91(2):465-73.
1992: J D Bartlett; J D Luethy; S G Carlson; STEVEN SOLLOTT; Nikki J Holbrook
Calcium ionophore A23187 induces expression of the growth arrest and DNA damage inducible CCAAT/enhancer-binding protein (C/EBP)-related gene, gadd153. Ca2+ increases transcriptional activity and mRNA stability.
The Journal of biological chemistry 1992;267(28):20465-70.
1992: J S Park; J D Luethy; M G Wang; J Fargnoli; Albert J Fornace; O W McBride; Nikki J Holbrook
Isolation, characterization and chromosomal localization of the human GADD153 gene.
Gene 1992;116(2):259-67.
1992: Nikki J Holbrook; S G Carlson; Augustine M K Choi; J Fargnoli
Induction of HSP70 gene expression by the antiproliferative prostaglandin PGA2: a growth-dependent response mediated by activation of heat shock transcription factor.
Molecular and cellular biology 1992;12(4):1528-34.
1992: Augustine M K Choi; J Fargnoli; S G Carlson; Nikki J Holbrook
Cell growth inhibition by prostaglandin A2 results in elevated expression of gadd153 mRNA.
Experimental cell research 1992;199(1):85-9.
1992: J D Luethy; Nikki J Holbrook
Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage.
Cancer research 1992;52(1):5-10.
1991: Robert Udelsman; M J Blake; Nikki J Holbrook
Molecular response to surgical stress: specific and simultaneous heat shock protein induction in the adrenal cortex, aorta, and vena cava.
Surgery 1991;110(6):1125-31.
1991: M J Blake; Robert Udelsman; G J Feulner; D D Norton; Nikki J Holbrook
Stress-induced heat shock protein 70 expression in adrenal cortex: an adrenocorticotropic hormone-sensitive, age-dependent response.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9873-7.
1991: M J Blake; J Fargnoli; D Gershon; Nikki J Holbrook
Concomitant decline in heat-induced hyperthermia and HSP70 mRNA expression in aged rats.
The American journal of physiology 1991;260(4 Pt 2):R663-7.
1991: L O'Neill; Nikki J Holbrook; J Fargnoli; Edward G Lakatta
Progressive changes from young adult age to senescence in mRNA for rat cardiac myosin heavy chain genes.
Cardioscience 1991;2(1):1-5.
1990: J D Luethy; J Fargnoli; J S Park; Albert J Fornace; Nikki J Holbrook
Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA.
The Journal of biological chemistry 1990;265(27):16521-6.
1990: M J Blake; D Gershon; J Fargnoli; Nikki J Holbrook
Discordant expression of heat shock protein mRNAs in tissues of heat-stressed rats.
The Journal of biological chemistry 1990;265(25):15275-9.
1990: M J Blake; T S Nowak; Nikki J Holbrook
In vivo hyperthermia induces expression of HSP70 mRNA in brain regions controlling the neuroendocrine response to stress.
Brain research. Molecular brain research 1990;8(1):89-92.
1990: J Fargnoli; T Kunisada; Albert J Fornace; E L Schneider; Nikki J Holbrook
Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):846-50.
1989: R K Chopra; Nikki J Holbrook; D C Powers; M T McCoy; W H Adler; J E Nagel
Interleukin 2, interleukin 2 receptor, and interferon-gamma synthesis and mRNA expression in phorbol myristate acetate and calcium ionophore A23187-stimulated T cells from elderly humans.
Clinical immunology and immunopathology 1989;53(2 Pt 1):297-308.
1989: Albert J Fornace; Daniel W Nebert; M Christine Hollander; J D Luethy; M Papathanasiou; J Fargnoli; Nikki J Holbrook
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.
Molecular and cellular biology 1989;9(10):4196-203.
1989: Nikki J Holbrook; R K Chopra; M T McCoy; J E Nagel; D C Powers; W H Adler; E L Schneider
Expression of interleukin 2 and the interleukin 2 receptor in aging rats.
Cellular immunology 1989;120(1):1-9.
1989: J P Quinn; M Takimoto; Michael Iadarola; Nikki J Holbrook; David Levens
Distinct factors bind the AP-1 consensus sites in gibbon ape leukemia virus and simian virus 40 enhancers.
Journal of virology 1989;63(4):1737-42.
1988: J E Nagel; R K Chopra; Francis J Chrest; M T McCoy; E L Schneider; Nikki J Holbrook; W H Adler
Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors.
The Journal of clinical investigation 1988;81(4):1096-102.
1987: J P Quinn; Nikki J Holbrook; David Levens
Binding of a cellular protein to the gibbon ape leukemia virus enhancer.
Molecular and cellular biology 1987;7(8):2735-44.
1987: R K Chopra; J E Nagel; Francis J Chrest; W M Boto; R S Pyle; B Dorsey; M McCoy; Nikki J Holbrook; W H Adler
Regulation of interleukin 2 and interleukin 2 receptor gene expression in human T cells: I. Effect of Ca2+-ionophore on phorbol myristate acetate co-stimulated cells.
Clinical and experimental immunology 1987;69(2):433-40.