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Julianne Holleran

Research Profile

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Tumor Cells, Cultured

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Publications

TOP 3
Anastasios Stathis; Sebastien J Hotte; Eric X Chen; Hal Hirte; Amit M Oza; Patricia Moretto; Sheila Webster; Anne Laughlin; Lee-Anne Stayner; Shauna McGill; Lisa Wang; Wen-jiang Zhang; Igor Espinoza-Delgado; Julianne L Holleran; Merrill J Egorin; Lillian L Siu
Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas.
Jan H Beumer; Julie L Eiseman; Judith A Gilbert; Julianne L Holleran; Archibong E Yellow-Duke; Dana M Clausen; David Z D'Argenio; Matthew M Ames; Pamela A Hershberger; Robert A Parise; Lihua Bai; Joseph M Covey; Merrill J Egorin
Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice.
Julianne L Holleran; Robert A Parise; Archibong E Yellow-Duke; Merrill J Egorin; Julie L Eiseman; Joseph M Covey; Jan H Beumer
Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776.

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All Publications

2011: Anastasios Stathis; Sebastien J Hotte; Eric X Chen; Hal Hirte; Amit M Oza; Patricia Moretto; Sheila Webster; Anne Laughlin; Lee-Anne Stayner; Shauna McGill; Lisa Wang; Wen-jiang Zhang; Igor Espinoza-Delgado; Julianne L Holleran; Merrill J Egorin; Lillian L Siu
Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1582-90.
2011: Jan H Beumer; Julie L Eiseman; Judith A Gilbert; Julianne L Holleran; Archibong E Yellow-Duke; Dana M Clausen; David Z D'Argenio; Matthew M Ames; Pamela A Hershberger; Robert A Parise; Lihua Bai; Joseph M Covey; Merrill J Egorin
Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice.
Cancer chemotherapy and pharmacology 2011;67(2):421-30.
2010: Julianne L Holleran; Robert A Parise; Archibong E Yellow-Duke; Merrill J Egorin; Julie L Eiseman; Joseph M Covey; Jan H Beumer
Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776.
Journal of pharmaceutical and biomedical analysis 2010;52(5):714-20.
2010: Marwan G Fakih; Gerald Fetterly; Merrill J Egorin; Josephia R Muindi; Igor Espinoza-Delgado; James Zwiebel; Alan Litwin; Julianne L Holleran; Kangsheng Wang; Robert B Diasio
A phase I, pharmacokinetic, and pharmacodynamic study of two schedules of vorinostat in combination with 5-fluorouracil and leucovorin in patients with refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(14):3786-94.
2010: Tapan M Kadia; Hui Yang; Alessandra Ferrajoli; Sirisha Maddipotti; Claudia Schroeder; Timothy L Madden; Julianne L Holleran; Merrill J Egorin; Farhad Ravandi; Deborah A Thomas; Willie Newsome; Blanca Sanchez-Gonzalez; James Zwiebel; Igor Espinoza-Delgado; Hagop M Kantarjian; Guillermo Garcia-Manero
A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia.
British journal of haematology 2010;150(1):72-82.
2010: Ramesh K Ramanathan; Merrill J Egorin; Charles Erlichman; Scot C Remick; Suresh S Ramalingam; Cynthia Naret; Julianne L Holleran; Cynthia J Teneyck; S Percy Ivy; Chandra P Belani
Phase I pharmacokinetic and pharmacodynamic study of 17-dimethylaminoethylamino-17-demethoxygeldanamycin, an inhibitor of heat-shock protein 90, in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(9):1520-6.
2010: Heidi Colville; Ryan Dzadony; Rebecca Kemp; Stephen Stewart; Herbert J Zeh; David L Bartlett; Julianne L Holleran; Kevin Schombert; Juliann E Kosovec; Merrill J Egorin; Jan H Beumer
In vitro circuit stability of 5-fluorouracil and oxaliplatin in support of hyperthermic isolated hepatic perfusion.
The Journal of extra-corporeal technology 2010;42(1):75-9.
2009: Courtney M Tate; Melissa L Fishel; Julianne L Holleran; Merrill J Egorin; David G Skalnik
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity.
DNA repair 2009;8(12):1411-23.
2009: Ashraf Badros; Angelika Burger; Sunita Philip; Ruben Niesvizky; Sarah S Kolla; Olga Goloubeva; Carolynn Harris; James Zwiebel; John J Wright; Igor Espinoza-Delgado; Maria R Baer; Julianne L Holleran; Merrill J Egorin; Steven Grant
Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(16):5250-7.
2009: Marwan G Fakih; Lakshmi Pendyala; Gerald Fetterly; Karoli Toth; James A Zwiebel; Igor Espinoza-Delgado; Alan Litwin; Youcef M Rustum; Mary Ellen Ross; Julianne L Holleran; Merrill J Egorin
A phase I, pharmacokinetic and pharmacodynamic study on vorinostat in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with refractory colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(9):3189-95.
2009: Herbert J Zeh; Charles K Brown; Matthew P Holtzman; Merrill J Egorin; Julianne L Holleran; Douglas M Potter; David L Bartlett
A phase I study of hyperthermic isolated hepatic perfusion with oxaliplatin in the treatment of unresectable liver metastases from colorectal cancer.
Annals of surgical oncology 2009;16(2):385-94.
2008: Cara A Rabik; Melissa L Fishel; Julianne L Holleran; Kristen Kasza; Mark R Kelley; Merrill J Egorin; M Eileen Dolan
Enhancement of cisplatin [cis-diammine dichloroplatinum (II)] cytotoxicity by O6-benzylguanine involves endoplasmic reticulum stress.
The Journal of pharmacology and experimental therapeutics 2008;327(2):442-52.
2008: Robert A Parise; Jan H Beumer; Cyrous O Kangani; Julianne L Holleran; Julie L Eiseman; Nicola F Smith; Joseph M Covey; Susan P Perrine; Merrill J Egorin
Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;862(1-2):168-74.
2006: Jan H Beumer; Julie L Eiseman; Robert A Parise; Erin Joseph; Julianne L Holleran; Joseph M Covey; Merrill J Egorin
Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7483-91.
2006: Robert A Parise; Julianne L Holleran; Jan H Beumer; Sakkaraiappan Ramalingam; Merrill J Egorin
A liquid chromatography-electrospray ionization tandem mass spectrometric assay for quantitation of the histone deacetylase inhibitor, vorinostat (suberoylanilide hydroxamicacid, SAHA), and its metabolites in human serum.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;840(2):108-15.
2005: Elizabeth R Glaze; Amy L Lambert; Adaline C Smith; John G Page; William D Johnson; David L McCormick; Alan P Brown; Barry S Levine; Joseph M Covey; Merrill J Egorin; Julie L Eiseman; Julianne L Holleran; Edward A Sausville; Joseph E Tomaszewski
Preclinical toxicity of a geldanamycin analog, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG), in rats and dogs: potential clinical relevance.
Cancer chemotherapy and pharmacology 2005;56(6):637-47.
2005: Julianne L Holleran; Robert A Parise; Erin Joseph; Julie L Eiseman; Joseph M Covey; Elizabeth R Glaze; Aleksander V. Lyubimov; Ya-Fei Chen; David Z D'Argenio; Merrill J Egorin
Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3862-8.
2004: Julianne L Holleran; Julien Fourcade; Merrill J Egorin; Julie L Eiseman; Robert A Parise; Steven M Musser; Kevin D White; Joseph M Covey; Gerald L Forrest; Su-Shu Pan
In vitro metabolism of the phosphatidylinositol 3-kinase inhibitor, wortmannin, by carbonyl reductase.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(5):490-6.
2003: Julianne L Holleran; Merrill J Egorin; Eleanor G Zuhowski; Robert A Parise; Steven M Musser; Su-Shu Pan
Use of high-performance liquid chromatography to characterize the rapid decomposition of wortmannin in tissue culture media.
Analytical biochemistry 2003;323(1):19-25.
2003: Lloyd A Culp; Wen-Chang Lin; Nanette Kleinman; Julianne L Holleran; Carson J Miller
Tumor-specific metastasis to lung using reporter gene-tagged tumor cells.
Methods in molecular medicine 2003;74():507-24.
2002: Julianne L Holleran; Carson J Miller; Nancy L Edgehouse; Theresa P Pretlow; Lloyd A Culp
Differential experimental micrometastasis to lung, liver, and bone with lacZ-tagged CWR22R prostate carcinoma cells.
Clinical & experimental metastasis 2002;19(1):17-24.
2001: Lloyd A Culp; Julianne L Holleran; Carson J Miller
Tracking prostate carcinoma micrometastasis to multiple organs using histochemical marker genes and novel cell systems.
Histology and histopathology 2001;16(3):945-53.
2000: Julianne L Holleran; Carson J Miller; Lloyd A Culp
Tracking micrometastasis to multiple organs with lacZ-tagged CWR22R prostate carcinoma cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(5):643-51.
1998: Lloyd A Culp; Wen-Chang Lin; Nanette Kleinman; N M Campero; Carson J Miller; Julianne L Holleran
Tumor progression, micrometastasis, and genetic instability tracked with histochemical marker genes.
Progress in histochemistry and cytochemistry 1998;33(3-4):XI-XV, 329-48.