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Lena Holm

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Cecilia Jädert; Jon O Lundberg; Sara Massena; Joel Petersson; David Ahl; Liza Grapensparr; Lena Holm; Mia Phillipson
Decreased leukocyte recruitment by inorganic nitrate and nitrite in microvascular inflammation and NSAID-induced intestinal injury.
Johan Dicksved; Lena Holm; Joel Petersson; Mia Phillipson; Sara Rang; Olof Schreiber; Ben Willing; Stefan Roos
Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction.
Lena Holm; Mia Phillipson
Assessment of mucus thickness and production in situ.

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All Publications

2012: Cecilia Jädert; Jon O Lundberg; Sara Massena; Joel Petersson; David Ahl; Liza Grapensparr; Lena Holm; Mia Phillipson
Decreased leukocyte recruitment by inorganic nitrate and nitrite in microvascular inflammation and NSAID-induced intestinal injury.
Free radical biology & medicine 2012;52(3):683-92.
2012: Johan Dicksved; Lena Holm; Joel Petersson; Mia Phillipson; Sara Rang; Olof Schreiber; Ben Willing; Stefan Roos
Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction.
PloS one 2012;7(9):e46399.
2012: Lena Holm; Mia Phillipson
Assessment of mucus thickness and production in situ.
Methods in molecular biology (Clifton, N.J.) 2012;842():217-27.
2011: R Kalmendal; K Elwinger; Lena Holm; Ragnar Tauson
High-fibre sunflower cake affects small intestinal digestion and health in broiler chickens.
British poultry science 2011;52(1):86-96.
2011: Joel Petersson; O Schreiber; Gunnar Hansson; Sandra J Gendler; Anna Velcich; Jon O Lundberg; S Roos; Lena Holm; Mia Phillipson
Importance and regulation of the colonic mucus barrier in a mouse model of colitis.
American journal of physiology. Gastrointestinal and liver physiology 2011;300(2):G327-33.
2010: L Jönsson; Lena Holm
Effects of toxic and non-toxic blue mussel meal on health and product quality of laying hens.
Journal of animal physiology and animal nutrition 2010;94(3):405-12.
2010: Malin E V Johansson; Jenny K Gustafsson; Karolina E Sjöberg; Joel Petersson; Lena Holm; Henrik Sjövall; Gunnar C Hansson
Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model.
PloS one 2010;5(8):e12238.
2009: Joel Petersson; Mattias Carlström; Olof Schreiber; Mia Phillipson; Gustaf Christoffersson; Annika Jägare; Stefan Roos; Emmelie A Jansson; A Erik G Persson; Jon O Lundberg; Lena Holm
Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash.
Free radical biology & medicine 2009;46(8):1068-75.
2009: Irina Gyllenhammar; Lena Holm; Rosita Eklund; Cecilia Berg
Reproductive toxicity in Xenopus tropicalis after developmental exposure to environmental concentrations of ethynylestradiol.
Aquatic toxicology (Amsterdam, Netherlands) 2009;91(2):171-8.
2009: Johanna Henriksnäs; Christer Atuma; Mia Phillipson; Stellan Sandler; Lars Engstrand; Lena Holm
Acute effects of Helicobacter pylori extracts on gastric mucosal blood flow in the mouse.
World journal of gastroenterology : WJG 2009;15(2):219-25.
2008: Mia Phillipson; Malin E V Johansson; Johanna Henriksnäs; Joel Petersson; Sandra J Gendler; Stellan Sandler; A Erik G Persson; Gunnar Hansson; Lena Holm
The gastric mucus layers: constituents and regulation of accumulation.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(4):G806-12.
2008: Malin E V Johansson; Mia Phillipson; Joel Petersson; Anna Velcich; Lena Holm; Gunnar Hansson
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15064-9.
2008: Emmelie A Jansson; Liyue Huang; Ronny Malkey; Mirco Govoni; Carina Nihlén; Annika Olsson; Margareta Stensdotter; Joel Petersson; Lena Holm; Eddie Weitzberg; Jon O Lundberg
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis.
Nature chemical biology 2008;4(7):411-7.
2007: Joel Petersson; Olof Schreiber; Andreas Steege; Andreas Patzak; Anna Hellsten; Mia Phillipson; Lena Holm
eNOS involved in colitis-induced mucosal blood flow increase.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(6):G1281-7.
2007: Joel Petersson; Mia Phillipson; Eva Jansson; Andreas Patzak; Jon O Lundberg; Lena Holm
Dietary nitrate increases gastric mucosal blood flow and mucosal defense.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(3):G718-24.
2007: Eva Jansson; Joel Petersson; Claudia Reinders; Tanja Sobko; Håkan Björne; Mia Phillipson; Eddie Weitzberg; Lena Holm; Jon O Lundberg
Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate.
Free radical biology & medicine 2007;42(4):510-8.
2006: Lena Holm; Alexandra Blomqvist; Ingvar Brandt; Björn Brunström; Yvonne Ridderstråle; Cecilia Berg
Embryonic exposure to o,p'-DDT causes eggshell thinning and altered shell gland carbonic anhydrase expression in the domestic hen.
Environmental toxicology and chemistry / SETAC 2006;25(10):2787-93.
2006: Johanna Henriksnäs; Mia Phillipson; Martin Storm; Lars Engstrand; Manoocher Soleimani; Lena Holm
Impaired mucus-bicarbonate barrier in Helicobacter pylori-infected mice.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(3):G396-403.
2006: Alexandra Blomqvist; Cecilia Berg; Lena Holm; Ingvar Brandt; Yvonne Ridderstråle; Björn Brunström
Defective reproductive organ morphology and function in domestic rooster embryonically exposed to o,p'-DDT or ethynylestradiol.
Biology of reproduction 2006;74(3):481-6.
2005: M A Perry; Mia Phillipson; Lena Holm
Transmural gradient of leukocyte-endothelial interaction in the rat gastrointestinal tract.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(5):G852-9.
2005: Jie Xu; Johanna Henriksnäs; Sharon Barone; David Witte; Gary E Shull; John G Forte; Lena Holm; Manoocher Soleimani
SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+.
American journal of physiology. Cell physiology 2005;289(2):C493-505.
2005: Johanna Henriksnäs; Mia Phillipson; Joel Petersson; Lars Engstrand; Lena Holm
An in vivo model for gastric physiological and pathophysiological studies in the mouse.
Acta physiologica Scandinavica 2005;184(2):151-9.
2004: Cecilia Berg; Alexandra Blomqvist; Lena Holm; Ingvar Brandt; Björn Brunström; Yvonne Ridderstråle
Embryonic exposure to oestrogen causes eggshell thinning and altered shell gland carbonic anhydrase expression in the domestic hen.
Reproduction (Cambridge, England) 2004;128(4):455-61.
2004: Elisabeth Ekstedt; Lena Holm; Yvonne Ridderstråle
Carbonic anhydrase in mouse testis and epididymis; transfer of isozyme IV to spermatozoa during passage.
Journal of molecular histology 2004;35(2):167-73.
2004: HåKan Björne H; Joel Petersson; Mia Phillipson; Eddie Weitzberg; Lena Holm; Jon O Lundberg
Nitrite in saliva increases gastric mucosal blood flow and mucus thickness.
The Journal of clinical investigation 2004;113(1):106-14.
2003: Mia Phillipson; Johanna Henriksnäs; Maria Holstad; Stellan Sandler; Lena Holm
Inducible nitric oxide synthase is involved in acid-induced gastric hyperemia in rats and mice.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(1):G154-62.
2003: Krister Halldin; Lena Holm; Yvonne Ridderstråle; Björn Brunström
Reproductive impairment in Japanese quail (Coturnix japonica) after in ovo exposure to o,p'-DDT.
Archives of toxicology 2003;77(2):116-22.
2002: Lena Holm; Mia Phillipson; M A Perry
NO-flurbiprofen maintains duodenal blood flow, enhances mucus secretion contributing to lower mucosal injury.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(5):G1090-7.
2002: S Larsdotter; Lena Holm; Kristina Dahlborn; Anna Jansson; M Josefsson; Yvonne Ridderstråle
Carbonic anhydrase activity and sweat gland morphology in trained and untrained Standardbred trotters.
Equine veterinary journal. Supplement 2002;(34):560-3.
2002: Mia Phillipson; Christer Atuma; Johanna Henriksnäs; Lena Holm
The importance of mucus layers and bicarbonate transport in preservation of gastric juxtamucosal pH.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(2):G211-9.
2002: Lena Holm; Yvonne Ridderstråle
Development of sperm storage tubules in the quail during sexual maturation.
The Journal of experimental zoology 2002;292(2):200-5.
2001: Lena Holm; Cecilia Berg; Björn Brunström; Yvonne Ridderstråle; Ingvar Brandt
Disrupted carbonic anhydrase distribution in the avian shell gland following in ovo exposure to estrogen.
Archives of toxicology 2001;75(6):362-8.
2001: Christer Atuma; Vicki Strugala; Adrian Allen; Lena Holm
The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(5):G922-9.
2001: Cecilia Berg; Lena Holm; Ingvar Brandt; Björn Brunström
Anatomical and histological changes in the oviducts of Japanese quail, Coturnix japonica, after embryonic exposure to ethynyloestradiol.
Reproduction (Cambridge, England) 2001;121(1):155-65.
2001: I Synnerstad; M Johansson; Olof Nylander; Lena Holm
Intraluminal acid and gastric mucosal integrity: the importance of blood-borne bicarbonate.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(1):G121-9.
2000: M Johansson; I Synnerstad; Lena Holm
Acid transport through channels in the mucous layer of rat stomach.
Gastroenterology 2000;119(5):1297-304.
2000: Lena Holm; SD Ruziwa; Vibeke Dantzer; Yvonne Ridderstråle
Carbonic anhydrase in the utero-vaginal junction of immature and mature ostriches.
British poultry science 2000;41(2):244-9.
2000: Lena Holm; Hans Ekwall; G J Wishart; Yvonne Ridderstråle
Localization of calcium and zinc in the sperm storage tubules of chicken, quail and turkey using X-ray microanalysis.
Journal of reproduction and fertility 2000;118(2):331-6.
2000: Yvonne Ridderstråle; Per J Wistrand; Lena Holm; ND Carter
Use of carbonic anhydrase II-deficient mice in uncovering the cellular location of membrane-associated isoforms.
EXS 2000;(90):143-55.
1999: Christer Atuma; Lars Engstrand; Lena Holm
Helicobacter pylori extracts reduce gastric mucosal blood flow by a nitric oxide-independent but mast cell- and platelet-activating factor receptor-dependent pathway in rats.
Scandinavian journal of gastroenterology 1999;34(12):1183-9.
1999: Kristina Dahlborn; Anna Jansson; S Nyman; K Morgan; Lena Holm; Yvonne Ridderstråle
Sweat production and localisation of carbonic anhydrase in the equine sweat gland during exercise at two ambient temperatures.
Equine veterinary journal. Supplement 1999;(30):398-403.
1998: Christer Atuma; Lars Engstrand; Lena Holm
Extracts of Helicobacter pylori reduce gastric mucosal blood flow through a VacA- and CagA-independent pathway in rats.
Scandinavian journal of gastroenterology 1998;33(12):1256-61.
1998: Lena Holm; G J Wishart
The effect of pH on the motility of spermatozoa from chicken, turkey and quail.
Animal reproduction science 1998;54(1):45-54.
1998: Lena Holm; Yvonne Ridderstråle
Localization of carbonic anhydrase in the sperm-storing regions of the turkey and quail oviduct.
The Histochemical journal 1998;30(7):481-8.
1998: I Synnerstad; Lena Holm
Prostaglandin E2 and aggressive factors increase the gland luminal pressure in the rat gastric mucosa in vivo.
Gastroenterology 1998;114(6):1276-86.
1998: I Synnerstad; E Ekblad; F Sundler; Lena Holm
Gastric mucosal smooth muscles may explain oscillations in glandular pressure: role of vasoactive intestinal peptide.
Gastroenterology 1998;114(2):284-94.
1997: I Synnerstad; A Erik G Persson; Lena Holm
Effect of inhibition of pentagastrin-stimulated acid secretion on gastric mucosal gland luminal pressure.
Acta physiologica Scandinavica 1997;160(1):103-11.
1997: I Synnerstad; Lena Holm
Omeprazole induces high intraglandular pressure in the rat gastric mucosa.
Gastroenterology 1997;112(4):1221-30.
1996: Lena Holm; Yvonne Ridderstråle; P G Knutsson
Localisation of carbonic anhydrase in the sperm storing regions of the domestic hen oviduct.
Acta anatomica 1996;156(4):253-60.
1995: M Sababi; E Nilsson; Lena Holm
Mucus and alkali secretion in the rat duodenum: effects of indomethacin, N omega-nitro-L-arginine, and luminal acid.
Gastroenterology 1995;109(5):1526-34.
1995: M Sababi; Lena Holm
Villus tip microcirculation in the rat duodenum.
Acta physiologica Scandinavica 1995;154(2):221-33.
1994: C Schade; Gunnar Flemström; Lena Holm
Hydrogen ion concentration in the mucus layer on top of acid-stimulated and -inhibited rat gastric mucosa.
Gastroenterology 1994;107(1):180-8.
1994: Olof Nylander; Lena Holm; Erik Wilander; A Hällgren
Exposure of the duodenum to high concentrations of hydrochloric acid. Effects on mucosal permeability, alkaline secretion, and blood flow.
Scandinavian journal of gastroenterology 1994;29(5):437-44.
1994: Lena Holm; A Jägare
Histamine is not involved in pentagastrin-induced gastric mucosal vasodilation in the rat.
The American journal of physiology 1994;266(1 Pt 1):G55-61.
1993: Olof Nylander; A Hällgren; Lena Holm
Duodenal mucosal alkaline secretion, permeability, and blood flow.
The American journal of physiology 1993;265(6 Pt 1):G1029-38.
1993: Lena Holm; A Jägare
Influence of tactile stimulation of the rat gastric mucosa on blood flow and acid output.
The American journal of physiology 1993;265(2 Pt 1):G303-9.
1993: Olof Nylander; Erik Wilander; G M Larson; Lena Holm
Vasoactive intestinal polypeptide reduces hydrochloric acid-induced duodenal mucosal permeability.
The American journal of physiology 1993;264(2 Pt 1):G272-9.
1992: Lena Holm; J Agren; A Erik G Persson
Stimulation of acid secretion increases the gastric gland luminal pressure in the rat.
Gastroenterology 1992;103(6):1797-803.
1992: P Morsing; Arne Stenberg; Daniel Casellas; A Mimran; C Müller-Suur; C Thorup; Lena Holm; A Erik G Persson
Renal interstitial pressure and tubuloglomerular feedback control in rats during infusion of atrial natriuretic peptide (ANP).
Acta physiologica Scandinavica 1992;146(3):393-8.
1992: Lena Holm; A Jägare
Role of prostaglandins in regulation of gastric mucosal blood flow and acid secretion.
The American journal of physiology 1992;263(4 Pt 1):G446-51.
1990: C Jönson; Lena Holm; Thomas B. Jansson; Lars Fändriks
Effects of hypovolemia on blood flow, arterial [HCO3-], and HCO3- output in the rat duodenum.
The American journal of physiology 1990;259(2 Pt 1):G179-83.
1990: Lena Holm; Gunnar Flemström; Olof Nylander
Duodenal alkaline secretion in rabbits: influence of artificial ventilation.
Acta physiologica Scandinavica 1990;138(4):471-8.
1990: Lena Holm; P Morsing; Daniel Casellas; A Erik G Persson
Resetting of the pressure range for blood flow autoregulation in the rat kidney.
Acta physiologica Scandinavica 1990;138(3):395-401.
1990: Lena Holm; Gunnar Flemström
Microscopy of acid transport at the gastric surface in vivo.
Journal of internal medicine. Supplement 1990;732():91-5.
1990: SO Granstam; C Jönson; Lars Fändriks; Lena Holm; Gunnar Flemström
Effects of cigarette smoke and nicotine on duodenal bicarbonate secretion in the rabbit and the rat.
Journal of clinical gastroenterology 1990;12 Suppl 1():S19-24.
1988: Lena Holm; M A Perry
Role of blood flow in gastric acid secretion.
The American journal of physiology 1988;254(3 Pt 1):G281-93.
1988: Lena Holm
Gastric mucosal blood flow and mucosal protection.
Journal of clinical gastroenterology 1988;10 Suppl 1():S114-9.